CN103055115A - 一种治疗婴儿湿疹的中成药 - Google Patents
一种治疗婴儿湿疹的中成药 Download PDFInfo
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Abstract
本发明提供一种治疗婴儿湿疹的中成药，其以重量份计，包含以下组分：荆芥5-7，防风5-7，牛蒡子5-7，蝉衣5-7，苦参5-7，知母5-7，黄柏5-7，苍术5-7，木通5-7，甘草2-4。相比于现有技术，本发明的中成药针对婴儿湿疹内在病邪，辨症施治，疗效快，成本低，且无毒副作用，效果显著，兼治标本。
Description
一种治疗婴儿湿疹的中成药
技术领域
[0001] 本发明涉及一种中成药，更具体地说，涉及一种治疗婴儿湿疹的中成药。
背景技术
[0002] 婴儿湿疹是一种变态反应性皮肤疾病，多发生在出生后I〜3月，大都为肥胖婴儿，常在I〜2岁即能自愈。其致敏原主要为蛋白质，如牛奶、鸡蛋等，此外药物、花粉、细菌、病毒、日光等也可导致本病发生。本病中医称“胎敛疮”、“奶癣”等。针对婴儿湿疹，西医常采用抗组织胺类药物、皮质类固醇激素、抗生素等进行治疗，但不能根治，且长期应用后有依赖性和各种不良反应。
发明内容
[0003] 本发明的目的是提供一种治疗婴儿湿疹的中成药，其针对婴儿湿疹内在病邪，辨症施治，针对性强，疗效快，成本低，且无毒副作用，能达起到很好的防治效果。
[0004] 为了实现上述的目的，本发明采用以下技术方案：一种治疗婴儿湿疹的中成药，以重量份计，包含以下组分：荆芥5-7，防风5-7，牛蒡子5-7，蝉衣5-7，苦参5_7，知母5_7，黄柏5-7，苍术5-7，木通5-7，甘草2-4。
[0005] 本发明中药物的机理分析：
荆芥：辛，微温。归肺、肝经。解表散风，透疹，消疮，止血。用于感冒，麻疹透发不畅，便血、崩漏、鼻衄。《滇南本草》: 治跌打损伤，并敷毒疮。治吐血。荆芥穗，上清头目诸风，止头痛，明目，解肺、肝、咽喉热痛，消肿，除诸毒，发散疮痈。治便血，止女子暴崩，消风热，通肺气鼻鸾塞闭。
[0006] 防风：味辛、甘，性微温。归膀胱、肝、脾经。祛风解表，胜湿止痛，止痉定搐。《本经》：主大风头眩痛，恶风，风邪，目盲无所见，风行周身，骨节疼痹，烦满。
[0007] 牛蒡子：味辛；苦；性寒。归肺；胃经。疏散风热；宣肺透疹；利咽散结；解毒消肿。用于风热咳嗽，咽喉肿痛，斑疹不透，风疹瘙痒，疮疡肿毒。《本草求真》:牛蒡子，今人止言解毒，凡遇疮疡痈肿、痘疹等症，无不用此投治，然犹未绎其义。
[0008] 蝉衣：味甘；咸；性凉。归肺；肝经。宣散风热；透疹利咽；退翳明目；祛风止痉。用于风热感冒，咽喉肿痛，咳嗽音哑，风疹瘙痒，目赤翳障，惊痫抽搐，破伤风。《纲目》:蝶，主疗皆一切风热证，古人用身，后人用蜕。大抵治脏府经络，当用蝉身；治皮肤疮疡风执，当用蝉蜕。
[0009] 苦参：味苦；性寒。归肝；肾；大肠；小肠经；膀胱；心经。清热燥湿；祛风杀虫。用于湿热泻痢，肠风便血，黄疸，小便不利，水肿，带下，阴痒，疥癣，麻风，皮肤瘙痒，湿毒疮疡。《药性论》：治热毒风，皮肌烦燥生疮，赤癞眉脱，主除大热嗜睡，治腹中冷痛，中恶腹痛，除体闷，治心腹积聚。
[0010] 知母：苦、甘，寒。归肺、胃、肾经。清热泻火，生津润燥。用于温热病邪热亢盛，壮热、烦渴、脉洪大等肺胃实热证。《日华子本草》：通小肠，消痰止嗽，润心肺，补虚乏，安心止惊悸。
[0011] 黄柏：苦；寒。归肾；膀胱经。清热燥湿；泻火解毒。用于湿热痢疾、泄泻、黄疸，梦遗、淋浊、带下，骨蒸劳热，口舌生疮，目赤肿痛，痈疽疮毒，皮肤湿疹。《药品化义》：黄柏，味苦入骨，是以降火能自顶至踵，沦肤彻髓，无不周到，专泻肾与膀胱之火。
[0012] 苍术：味辛；苦；性温。归脾；胃；肝经。燥湿健脾；祛风湿；明目。用于湿困脾胃，倦怠嗜卧，胞痞腹胀，食欲不振，哎吐泄泻，痰饮，湿肿，表证夹湿，头身重痛，痹证温性，肢节酸痛重着，痿襞，夜盲。《本草纲目》：治湿痰留饮，或挟瘀血成窠囊，及脾湿下流，浊浙带下，滑泻肠风。
[0013] 木通：苦、微寒。入心经、小肠经、膀胱经。清心火，利小便，通经下乳。用于胸中烦热,喉痹咽痛,尿赤,五淋,水肿,周身挛痛,经闭乳少。《药性论》:主治五淋,利小便,开关格，治人多睡，主水肿浮大，除烦热。
[0014] 甘草：性平，味甘，归十二经。补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。
[0015] 针对湿热内盛所致的婴儿湿疹症状，中医认为患儿素体血热,复感风热之邪,或内湿化热，搏结于肌肤，故见皮肤潮红，红色丘疹、水疱等。看红苔黄，脉滑数，均为湿热内盛之象。
[0016] 方中之选者，清热利湿，祛风止痒。荆芥解表散风，防风祛风解表，牛蒡子疏散风热，蝉衣宣散风热，苦参清热燥湿，知母清热泻火，黄柏泻火解毒，苍术燥湿健脾，木通清心火，甘草清热解毒。全方共奏，清热利湿，祛风止痒，平衡机体阴阳。针对湿热内盛所致的婴儿湿疹症状，辨症施治，疗效快，成本低，疗效确切，防治效果显著，兼治标本。
[0017] 本发明的中药剂型 可以采用片剂、颗粒剂、丸剂、胶囊剂、溶液剂、口服液、口含片、颗粒剂、冲剂、散剂、混悬剂、粉剂。优选地，可以采用溶液剂、颗粒剂、丸剂和胶囊剂。
[0018] 使用效果
对30名婴儿湿疹患者（30-60周龄）使用本发明的治疗婴儿湿疹的中成药，持续治疗I个疗程（10天)，其中13例完全治愈，指标恢复正常；15例症状缓解；无效2例，总体有效率达93. 3%,且无复发。
[0019]实例：
患者1:许某，男性，40周龄，皮肤潮红，额头现红色丘疹，干后结痂，眼周发红，舌质红，舌苔薄黄腻，脉滑数。诊断为婴儿湿疹，服用本发明的中成药I周，皮肤基本恢复正常，继续用药3日，症状完全消失，至今2个月无复发。
[0020] 患者2 :劳某，女性，33周龄，在脸部、耳后、四肢区侧、胸部、手部出现了对称的红块，发痒，哭闹，舌质红，舌苔薄黄腻。经诊断为婴儿湿疹，后服用本发明的中成药2周，上述症状全部消失，至今3个月未见发作。
[0021] 患者3 :袁某，女性，50周龄，皮肤潮红，长水疱，水疱破后流出粘液，干后结痂，舌质红，舌苔薄黄腻，脉滑数。诊断为婴儿湿疹，后来使用本发明的中成药进行治疗，4天后，症状好转，继续用药6天，上述症状均消失，至今无复发。
[0022] 患者4:叶某，男性，37周龄，脖子下面、胳膊底下、屁股下面出现很多湿疹，很痒，影响晚上睡眠。使用本发明的中成药进行治疗，I周后症状稳定并好转，继续用药3日，症状消失，无复发。具体实施方式
[0023] 为了更好地理解本发明，下面通过实施例来描述本发明。
[0024] 实施例1
一种治疗婴儿湿疹的中成药，以重量份计，包含以下组分：荆芥5，防风5，牛蒡子5，蝉衣5，苦参5，知母5，黄柏5，苍术5，木通5，甘草2。
[0025] 其制备方法为：
以重量份计，取荆芥5，防风5，牛蒡子5，蝉衣5，苦参5，知母5，黄柏5，苍术5，木通5，甘草2 ;将上述中药洗净，去杂质，放入容器加水没过药材浸泡，30分钟后，大火煎煮至沸腾，然后文火慢熬I小时；将药汁滤出，分袋包装，一袋200ml，早晚各服一袋。
[0026] 实施例2
一种治疗婴儿湿疹的中成药，以重量份计，包含以下组分：荆芥7，防风7，牛蒡子7，蝉衣7，苦参7，知母7，黄柏7，苍术7，木通7，甘草4。
[0027] 其制备方法为：
以重量份计，取荆芥7，防风7，牛蒡子7，蝉衣7，苦参7，知母7，黄柏7，苍术7，木通7，甘草4 ;洗净，干燥，将上述药材 混合，每公斤加入大约IOL水，文火煎0. 5-1小时，大火煎1-2小时；取煎液过150目筛，后用浓缩器浓缩至相对密度1. 10-1. 20的清膏，取2/3清膏在120°C下喷雾干燥，得清膏粉末，将粉末与剩余1/3清膏混合，制粒；颗粒分装机分装，即得颗粒剂。
[0028] 实施例3
一种治疗婴儿湿疹的中成药，以重量份计，包含以下组分：荆芥6，防风6，牛蒡子6，蝉衣6，苦参6，知母6，黄柏6，苍术6，木通6，甘草3。
[0029] 其制备方法为：
以重量份计,取荆芥6,防风6,牛蒡子6,蝶衣6,苦参6,知母6,黄柏6,苍术6,木通6,甘草3 ;洗净，干燥，将上述药材混合，用粉碎机粉碎为150-180目细粉，加入适当蜂蜜混合，制丸机制丸，低温干燥，分装，即得丸剂。
[0030] 实施例4
一种治疗婴儿湿疹的中成药，以重量份计，包含以下组分：荆芥6，防风6，牛蒡子6，蝉衣6，苦参6，知母6，黄柏6，苍术6，木通6，甘草3。
[0031] 其制备方法为：
以重量份计,取荆芥6,防风6,牛蒡子6,蝶衣6,苦参6,知母6,黄柏6,苍术6,木通6,甘草3 ;洗净，干燥，将上述药材混合，每公斤加入大约IOL水，文火煎0. 5-1小时，大火煎1-2小时；取煎液过150目筛，后用浓缩器浓缩至相对密度1. 10-1. 20的清膏，取2/3清膏在120°C下喷雾干燥，得清膏粉末，将粉末与剩余1/3清膏混合，制粒；将颗粒用胶囊填充剂制成0. 4g/粒胶囊。
Claims (4)
1. 一种治疗婴儿湿疹的中成药，其特征在于，以重量份计，包含以下组分：荆芥5-7，防风5-7，牛蒡子5-7，蝉衣5-7，苦参5-7，知母5_7，黄柏5_7，苍术5_7，木通5_7，甘草2_4。
2.根据权利要求1所述的中成药，其特征在于，以重量份计，优选包含以下组分：荆芥6，防风6,牛蒡子6,蝶衣6,苦参6,知母6,黄柏6,苍术6,木通6,甘草3。
3.根据权利要求1所述的中成药，其特征在于，所述中成药采用片剂、颗粒剂、丸剂、胶囊剂、溶液剂、口服液、口含片、颗粒剂、冲剂、散剂、混悬剂、粉剂。
4.根据权利要求1所述的中成药，其特征在于，所述中成药优选采用溶液剂、颗粒剂、丸剂和胶囊剂。
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| CN104524345A (zh) * | 2015-01-26 | 2015-04-22 | 何丹 | 一种治疗小儿湿疹的中药 |
| CN106176525A (zh) * | 2016-08-10 | 2016-12-07 | 湖北灵参中药科技有限公司 | 一种中草药植物沐浴露 |
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| 朱大年，等: "《一百天学中医儿科》", 31 October 2001, 上海科学技术出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104524345A (zh) * | 2015-01-26 | 2015-04-22 | 何丹 | 一种治疗小儿湿疹的中药 |
| CN106176525A (zh) * | 2016-08-10 | 2016-12-07 | 湖北灵参中药科技有限公司 | 一种中草药植物沐浴露 |
| CN106176525B (zh) * | 2016-08-10 | 2019-03-01 | 湖北灵参中药科技有限公司 | 一种中草药植物沐浴露 |
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