CN103040065B - Apple vinegar beverage for treating and preventing hiccups and preparation method thereof - Google Patents

Apple vinegar beverage for treating and preventing hiccups and preparation method thereof Download PDF

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CN103040065B
CN103040065B CN201310025877.1A CN201310025877A CN103040065B CN 103040065 B CN103040065 B CN 103040065B CN 201310025877 A CN201310025877 A CN 201310025877A CN 103040065 B CN103040065 B CN 103040065B
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apple
vinegar beverage
apple vinegar
hiccups
content
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CN103040065A (en
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刘子放
张友胜
吴继军
温靖
李升锋
唐道邦
张岩
刘军
马永轩
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GUANGDONG BOSUN HEALTH FOOD RESEARCH DEVELOPMENT CENTER
Sericulture and Agri Food Research Institute GAAS
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GUANGDONG BOSUN HEALTH FOOD RESEARCH DEVELOPMENT CENTER
Sericulture and Agri Food Research Institute GAAS
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Abstract

The invention belongs to the field of beverage preparation, and discloses an apple vinegar beverage for treating and preventing hiccups and a preparation method of the apple vinegar beverage. The apple vinegar beverage is prepared from pure water, raw apple vinegar, fresh apple juice, vine tea extracts, dried tangerine or orange peel essential oil, clove essential oil, mulberry honey, litchi honey, white sugar, aspartame, a citric acid, caramel pigments and potassium sorbate. The apple vinegar beverage disclosed by the invention is reasonable in formula, and fully utilizes the respective characteristics of various raw materials, and through the reasonable combination of raw materials, the apple vinegar beverage plays a comprehensive curative role; through experimental verification, the apple vinegar beverage has an extremely obvious curative effect on hiccup treatment, thereby achieving the purpose of treating both symptoms and root causes; and the apple vinegar beverage is simple in processing and manufacturing, and easy to take, and the apple vinegar beverage provides an ideal food for treating and preventing hiccups.

Description

Apple vinegar beverage that a kind for the treatment of and prevention are had the hiccups and preparation method thereof
Technical field
The invention belongs to drink formula field, apple vinegar beverage that particularly a kind for the treatment of and prevention are had the hiccups and preparation method thereof.
Background technology
Having the hiccups is hiccup, refers to gas superinverse from stomach, between larynx, again and again utters a word, and sound is anxious and very brief, and making us to be independently the illness of feature, is common phenomenon on a physiology.Have the hiccups and cause because diaphragmatic spasm shrinks.It shrinks at every turn reposefully, and our lung just sucks without a break; Because it is to be controlled by brain respiratory center, diaphram can be movable regularly, and our breathing can completely independently operate, and we do not need often remembering how to breathe yet.While having the hiccups, the contraction that diaphragm flesh be can't help, air is by rapid inspiration lung, and narrow suddenly in the crack among two vocal cords, thereby cause the strange sound.
The reason of having the hiccups has multiple, and the general state of an illness is not heavy, can disappear voluntarily.But also the sustainable long period of some case, become intractable and have the hiccups.This class current doctor trained in Western medicine of having the hiccups cannot accurately judge the concrete cause of disease clinically, also without good methods for the treatment of, therefore mainly adopts clinically Chinese traditional treatment method.Doctor trained in Western medicine thinks due to due to diaphragmatic spasm, and can be divided into coldness in the stomach, stomach Qi upward reversal, the resistance of circulation of vital energy in the wrong direction phlegm, YANG deficiency of the spleen and stomach, deficiency of stomach-Yin etc. during Chinese medical discrimination.Intractable is had the hiccups and is mostly occurred at mid-aged population, can adopt looser medical treatment of tcm prescription belch.
Research discovery, hiccup can be controlled particularly spreading out of or afferent nerve of diaphram of respiratory muscle by stimulating, and medullary substance maincenter etc. causes.Also have at present a lot of folkd therapies can cure hiccup, these methods be all based on principle of uniformity, and when in blood, carbon dioxide is assembled, hiccup just can stop.While holding the breath, in blood, gas concentration lwevel just can increase, and therefore available this principle is prevented hiccup.To a paper bag internal respiration, also can improve the level of carbon dioxide in blood.Fast drinking-water, swallow rusk or trash ice fast, can stimulate the vagus nerve that is sent and arranged stomach by brain, thereby hiccup is stopped.Also can carry out vagus nerve stimulation by the method for tractive tongue or the eyelid that gently rubs one's eyes gently.These methods are effective to most of hiccup patients.Additive method also comprises gastric lavage, electro photoluminescence nervus phrenicus, with little bougienage oesophagus etc., sucks containing 5%CO 2oxygen also can be effective, opponent's postoperative patient particularly, to diaphram pleurisy patient, using tight lower breast to drag can be helpful.The drug therapy of continuation hiccup is comprised to hyoscine, amphetamine, prochlorperazine, chlorpromazine, phenobarbital or anesthetic etc.10~20 milligrams of metoclopramides, oral, every day 2~4 times, may be effectively to some patient, then the success rate of drug therapy is still difficult to determine.To bothersome intractable patient, available following methods treatment on probation: 1, a small amount of 0.5% procaine is done nervus phrenicus sealing, should note avoiding respiration inhibition and pneumothorax; 2,10 milligrams of sublingual administrations of nifepine, if still hiccup is more than in half an hour, can chases after and take 10 milligrams.But repeat administration should be over 100 milligrams in 24 hours; 3, important on the one hand, acupuncture and moxibustion therapy on the one hand, comprises type Treated with Point-injection Therapy and acupoint medicinal injection treatment; 4, diaphragm pacing treatment intractable hiccup.But drug therapy meeting produces certain toxic and side effect, and cannot effect a radical cure persistent ailment, fall flat, in the urgent need to a kind of method simple and evident in efficacy.
Summary of the invention
In order to solve above-mentioned the deficiencies in the prior art part, the apple vinegar beverage that provides a kind for the treatment of and prevention to have the hiccups is provided primary and foremost purpose of the present invention.
Another object of the present invention is to provide the preparation method of above-mentioned apple vinegar beverage.
Object of the present invention realizes by following technical proposals: the apple vinegar beverage that a kind for the treatment of and prevention are had the hiccups, and this apple vinegar beverage is made by following raw material by mass percentage:
Figure BDA00002765799800021
Figure BDA00002765799800031
Above-mentioned apple vinegar beverage is more preferably by following raw material by mass percentage and makes:
Figure BDA00002765799800041
Total acid in the former vinegar of described apple is counted mass percent 10.0~10.5% with malic acid, folate content >=120 μ gDFE/1000ml, biotin content >=90.0 μ g/1000ml, content of choline >=190.0mg/1000ml, vitamin A content >=600 μ gRE/1000ml, content of vitamin E >=12.00mg α-TE/1000ml, cobalamin content >=2.00 μ g/1000ml, Nicotinic Acid Content >=10.00mg/1000ml;
In described Maoyanmei tea extract, the mass content of dibydro myricetrin monomer component is 40~48%, and the mass content of myricetin monomer component is 4~4.2%;
Mass content >=70% of eugenol in described clove oil;
In described dried orange peel essential oil, the mass content of D-citrene is 10%, and the mass content of beta-myrcene is 5~6%;
1-DNJ (DNJ) mass content >=0.5% in described sorosis honey;
Lichee polysaccharide mass content >=10% in described lichee honey.
Described white sugar, Aspartame, citric acid, caramel colorant and potassium sorbate are delicatessen food level.
The former vinegar of described apple is to adopt Shandong product Fuji apple to carry out secondary fermentation to prepare, and during fermentation, fermentation temperature is controlled at 16~17 ℃; Described fresh apple juice is to adopt Shandong product Fuji apple to adopt to squeeze the juice to prepare with filter method.
Described Maoyanmei tea extract is to prepare according to the following steps: adopting the Maoyanmei tea of Zhangjiajie, Hunan self-sow (is vine tea, ampelopsis grossedentata), adopt after drying water extraction method or ethanol extraction method to obtain Maoyanmei tea extract, more spray-dried method obtain Maoyanmei tea extract;
Described dried orange peel essential oil prepares according to the following steps: adopt storage period to surpass the Guangdong four meeting dried orange peels of 5 years, dry, pulverize, obtain dried orange peel dry powder; Dried orange peel dry powder is adopted to steam distillation distillation, and gained fraction extracted with diethyl ether, is extracted liquid; Extract is dried with anhydrous sodium sulfate, then reduced pressure concentration, reclaim ether, obtain dried orange peel essential oil;
Described clove oil prepares according to the following steps: cloves is dried, pulverized, obtain dry clove powder; Dry clove powder is adopted to steam distillation distillation, and gained fraction extracted with diethyl ether, is extracted liquid; Extract is dried with anhydrous sodium sulfate, then reduced pressure concentration, reclaim ether, obtain clove oil.
Described sorosis honey is that sorosis honey is produced in Guangdong; Described lichee honey is that lichee honey is produced in Guangdong.
The preparation method of the apple vinegar beverage that above-mentioned treatment and prevention are had the hiccups, comprise following operating procedure: by said ratio, take the former vinegar of apple, fresh apple juice, Maoyanmei tea extract, dried orange peel essential oil, clove oil, sorosis honey, lichee honey, white sugar, Aspartame, citric acid, caramel colorant and potassium sorbate and be placed in blend tank, add pure water to dissolve, mix, then ultrahigh-temperature instant Biocidal treatment method (UHT) carries out sterilization, canned, must to treat and prevent to have the hiccups apple vinegar beverage.
Described ultrahigh-temperature instant Biocidal treatment method is sterilizing 3~5s under 115~120 ℃ of conditions of temperature.
Principle of the present invention is:
The former vinegar of apple: the smell of fruits is very sweet is sour-sweet soft, clearly good to eat, move one deeply, be rich in aspartic acid, serine, the aminoacid ingredient of the needed by human body such as tryptophan, and 10 several mineral materials such as phosphorus, iron, zinc, pectin, vitamin, mineral matter and ferment, a large amount of vitamin antioxidants, wherein VC content 10 times more than of apples especially.The present invention requires total acid content, folate content, biotin content, content of choline, vitamin A content, content of vitamin E, cobalamin content, the Nicotinic Acid Content in the former vinegar of apple to require the level that reaches certain, its objective is in order to impel each composition to play synergy, while stoping human body to be subject to suddenly overheated or pungent stimulation, CO in body inner blood 2unexpected acute variation and cause hiccup.
Maoyanmei tea extract: the Mao Yan certain kind of berries is the strange generation jewellery in pure natural wild plant, the treasure-house of Compendium of Materia Medica has been enriched in its appearance, through national Duo Jia authoritative institution, identify, 17 seed amino acids and 14 kinds of trace elements containing needed by human, containing thick protein 12.8~13.8%, general flavone content 7.5~8.3%, minimum 6%, by the Ministry of Public Health, issue health food certificate approval general flavone content >=6%, its contained flavones can be got rid of the harmful acid of human body and eliminate and ketoboidies, remove the blood dirt in blood, regulate blood fat, reduce blood pressure, softening vessel effect is remarkable, the flavones energy sterilization anti-inflammatory containing, clearing heat and detoxicating, analgesia detumescence, blood fat-reducing blood pressure-decreasing, cough-relieving wets one's whistle, regulate and improve body immunity, to Staphylococcus aureus, first, beta streptococcus, Diplococcus pneumopniae, Bacillus influenzaes etc. have the very strong ability of killing.The object that the present invention uses this raw material and requires the content ratio of dibydro myricetrin and myricetin wherein to reach certain limit is in order to stop human body diaphragmatic spasm to shrink as far as possible, to cause hiccup.
The object of dried orange peel essential oil compatibility clove oil is to utilize it collaborative intestines and stomach are carried out to gentleness stimulate, and promotes the secretion of digestive juice, gets rid of pneumatosis in intestinal tube, strengthens the effectiveness of gas under its fragrant stomach invigorating and wind dispelling, simultaneously can be excited myocardium, and make blood vessel produce slight contraction.
Lichee honey: honey of lychee flowers picks up from the nectar of lichee pistil, breath is full of fragrance, taste is sweet, micro-band litchi tart flavour, existing honey clear and rich, but because added the distinctive composition of various honeybees oneself during Mel, therefore scorching without lichee, but it is special promotes the production of body fluid, beneficial blood, regulate the flow of vital energy, effect honey of lychee flowers bowl spares emergency, can five viscera settling.Through modern medicine study, prove, in honey of lychee flowers, distinctive active component is lichee polysaccharide, to promoting, digests and assimilates, and improves a poor appetite, and calming soporific improves human immunological competence.
Sorosis honey be by bee release in mulberry tree garden and the honey obtaining, wherein the distinctive composition of existing common honey oneself, has again distinctive active component 1-DNJ (DNJ) in mulberry tree; 1-DNJ is a kind of alkaloid, has the multiple pharmacologically actives such as hypoglycemic, antitumor and antiviral.
The relative prior art of the present invention, have following advantage and beneficial effect: (1) the present invention fill a prescription rationally, take full advantage of the characteristic that each raw material possesses separately, rationally assembly makes its performance comprehensive therapeutic effect, very obvious to the result for the treatment of of having the hiccups through experimental verification, reached the object for the treatment of both principal and secondary aspect of disease; (2) processing and fabricating is simple, and taking convenience provides a kind of desirable food for preventing and treating to have the hiccups.
The specific embodiment
Below in conjunction with embodiment, the present invention is described in further detail, but embodiments of the present invention are not limited to this.
Each raw material sources that following examples are used are as follows:
1, the former vinegar of apple is to adopt Shandong product Fuji apple to carry out secondary fermentation to prepare, and during fermentation, fermentation temperature is controlled at 16~17 ℃; Total acid in the former vinegar of this apple is counted mass percent 10.0~10.5% with malic acid, folate content >=120 μ gDFE/1000ml, biotin content >=90.0 μ g/1000ml, content of choline >=190.0mg/1000ml, vitamin A content >=600 μ gRE/1000ml, content of vitamin E >=12.00mg α-TE/1000ml, cobalamin content >=2.00 μ g/1000ml, Nicotinic Acid Content >=10.00mg/1000ml.
2, fresh apple juice is that the product Fuji apple employing of employing Shandong is squeezed the juice and filter method prepares.
3, Maoyanmei tea extract is to prepare according to the following steps: adopting the Maoyanmei tea of Zhangjiajie, Hunan self-sow (is vine tea, ampelopsis grossedentata), adopt after drying water extraction method or ethanol extraction method to obtain Maoyanmei tea extract, more spray-dried method obtain Maoyanmei tea extract; In this Maoyanmei tea extract, the mass content of dibydro myricetrin monomer component is 40~48%, and the mass content of myricetin monomer component is 4~4.2%.
4, dried orange peel essential oil prepares according to the following steps: adopt storage period to surpass the Guangdong four meeting dried orange peels of 5 years, dry, pulverize, obtain dried orange peel dry powder; Dried orange peel dry powder is adopted to steam distillation distillation, and gained fraction extracted with diethyl ether, is extracted liquid; Extract is dried with anhydrous sodium sulfate, then reduced pressure concentration, reclaim ether, obtain dried orange peel essential oil; In this dried orange peel essential oil, the mass content of D-citrene is 10%, and the mass content of beta-myrcene is 5~6%.
5, clove oil prepares according to the following steps: cloves is dried, pulverized, obtain dry clove powder; Dry clove powder is adopted to steam distillation distillation, and gained fraction extracted with diethyl ether, is extracted liquid; Extract is dried with anhydrous sodium sulfate, then reduced pressure concentration, reclaim ether, obtain clove oil; Mass content >=70% of eugenol in this clove oil.
6, described sorosis honey is that " Bao Sheng garden board " sorosis honey, wherein mass content >=0.5% of 1-DNJ (DNJ) are produced in Guangdong; Described lichee honey is that " Bao Sheng garden board " lichee honey, wherein mass content >=10% of lichee polysaccharide is produced in Guangdong.
Embodiment 1:
Take the former vinegar of apple of mass percent 5.350%, the fresh apple juice of mass percent 9.100%, the Maoyanmei tea extract of mass percent 0.100%, the dried orange peel essential oil of mass percent 0.075%, the clove oil of mass percent 0.175%, the sorosis honey of mass percent 0.225%, the lichee honey of mass percent 0.325%, the white sugar of mass percent 4.500%, the Aspartame of mass percent 0.025%, the citric acid of mass percent 0.130%, the potassium sorbate of the caramel colorant of mass percent 0.120% and mass percent 0.020% is placed in blend tank, add the pure water of mass percent 79.855% to dissolve, mix, then adopt ultrahigh-temperature instant Biocidal treatment method (UHT) sterilization 5s under 115 ℃ of conditions of temperature, canned, obtain the apple vinegar beverage that the present invention's treatment and prevention are had the hiccups.
Embodiment 2
Take the former vinegar of apple of mass percent 5.391%, the fresh apple juice of mass percent 9%, the Maoyanmei tea extract of mass percent 0.1%, the dried orange peel essential oil of mass percent 0.074%, the clove oil of mass percent 0.170%, the sorosis honey of mass percent 0.220%, the lichee honey of mass percent 0.320%, the white sugar of mass percent 4.45%, the Aspartame of mass percent 0.020%, the citric acid of mass percent 0.120%, the potassium sorbate of the caramel colorant of mass percent 0.115% and mass percent 0.02% is placed in blend tank, add the pure water of mass percent 80% to dissolve, mix, then adopt ultrahigh-temperature instant Biocidal treatment method (UHT) sterilization 3s under 120 ℃ of conditions of temperature, canned, obtain the apple vinegar beverage that the present invention's treatment and prevention are had the hiccups.
Embodiment 3
Take the former vinegar of apple of mass percent 5%, the fresh apple juice of mass percent 9.2%, the Maoyanmei tea extract of mass percent 0.12%, the dried orange peel essential oil of mass percent 0.076%, the clove oil of mass percent 0.180%, the sorosis honey of mass percent 0.230%, the lichee honey of mass percent 0.330%, the white sugar of mass percent 4.55%, the Aspartame of mass percent 0.030%, the citric acid of mass percent 0.140%, the potassium sorbate of the caramel colorant of mass percent 0.125% and mass percent 0.025% is placed in blend tank, add the pure water of mass percent 79.994% to dissolve, mix, then adopt ultrahigh-temperature instant Biocidal treatment method (UHT) sterilization 4s under 118 ℃ of conditions of temperature, canned, obtain the apple vinegar beverage that the present invention's treatment and prevention are had the hiccups.
Embodiment 4
Take the former vinegar of apple of mass percent 5.5%, the fresh apple juice of mass percent 9.015%, the Maoyanmei tea extract of mass percent 0.11%, the dried orange peel essential oil of mass percent 0.075%, the clove oil of mass percent 0.170%, the sorosis honey of mass percent 0.225%, the lichee honey of mass percent 0.330%, the white sugar of mass percent 4.50%, the Aspartame of mass percent 0.020%, the citric acid of mass percent 0.120%, the potassium sorbate of the caramel colorant of mass percent 0.115% and mass percent 0.02% is placed in blend tank, add the pure water of mass percent 79.8% to dissolve, mix, then adopt ultrahigh-temperature instant Biocidal treatment method (UHT) sterilization 5s under 116 ℃ of conditions of temperature, canned, obtain the apple vinegar beverage that the present invention's treatment and prevention are had the hiccups.
Embodiment 5
With the apple vinegar beverage that embodiment 1 gained treatment and prevention are had the hiccups, treat 50 routine hiccup patients, take each 250ml every day 3 times; Wherein, man's 30 examples, female's 20 examples, 20~60 years old age, 1~3 day hiccup duration, result: effective (taking hiccup in 3 days disappears, stop treating rear without recurrence) 10 examples (20%), effectively (take hiccup hour in 3 days, but send out again subsequently, treatment is still effective again) 35 examples (70%), invalid (taking hiccup in 3 days does not alleviate and do not disappear) 5 examples (10%).
Embodiment 6
With the apple vinegar beverage that embodiment 2 gained treatments and prevention are had the hiccups, treat 30 routine hiccup patients, take each 200ml every day 5 times; Wherein, man's 18 examples, female's 12 examples, 18~60 years old age, 1~3 day hiccup duration, result: effective (taking hiccup in 3 days disappears, stop treating rear without recurrence) 9 examples (30%), effectively (take hiccup hour in 3 days, but send out again subsequently, treatment is still effective again) 17 examples (56.7%), invalid (taking hiccup in 3 days does not alleviate and do not disappear) 4 examples (13.3%).
Above-described embodiment is preferably embodiment of the present invention; but embodiments of the present invention are not restricted to the described embodiments; other any do not deviate from change, the modification done under Spirit Essence of the present invention and principle, substitutes, combination, simplify; all should be equivalent substitute mode, within being included in protection scope of the present invention.

Claims (8)

1. the apple vinegar beverage that treatment and prevention are had the hiccups, is characterized in that: this apple vinegar beverage is made by following raw material by mass percentage:
Figure FDA0000452334730000011
Total acid in the former vinegar of described apple is counted mass percent 10.0~10.5% with malic acid, folate content >=120 μ gDFE/1000ml, biotin content >=90.0 μ g/1000ml, content of choline >=190.0mg/1000ml, vitamin A content >=600 μ gRE/1000ml, content of vitamin E >=12.00mg α-TE/1000ml, cobalamin content >=2.00 μ g/1000ml, Nicotinic Acid Content >=10.00mg/1000ml;
In described Maoyanmei tea extract, the mass content of dibydro myricetrin monomer component is 40~48%, and the mass content of myricetin monomer component is 4~4.2%.
2. the apple vinegar beverage that a kind for the treatment of according to claim 1 and prevention are had the hiccups, is characterized in that: this apple vinegar beverage is made by following raw material by mass percentage:
Figure FDA0000452334730000021
3. the apple vinegar beverage that a kind for the treatment of according to claim 1 and prevention are had the hiccups, is characterized in that:
Mass content >=70% of eugenol in described clove oil;
In described dried orange peel essential oil, the mass content of D-citrene is 10%, and the mass content of beta-myrcene is 5~6%;
1-DNJ (DNJ) mass content >=0.5% in described sorosis honey;
Lichee polysaccharide mass content >=10% in described lichee honey.
4. the apple vinegar beverage that a kind for the treatment of according to claim 1 and prevention are had the hiccups, is characterized in that: the former vinegar of described apple is to adopt Shandong product Fuji apple to carry out secondary fermentation to prepare, and during fermentation, fermentation temperature is controlled at 16~17 ℃; Described fresh apple juice is to adopt Shandong product Fuji apple to adopt to squeeze the juice to prepare with filter method.
5. the apple vinegar beverage that a kind for the treatment of according to claim 1 and prevention are had the hiccups, it is characterized in that: described Maoyanmei tea extract is to prepare according to the following steps: the Maoyanmei tea that adopts Zhangjiajie, Hunan self-sow, adopt after drying water extraction method or ethanol extraction method to obtain Maoyanmei tea extract, more spray-dried method obtain Maoyanmei tea extract;
Described dried orange peel essential oil is to prepare according to the following steps: adopt storage period to surpass the Guangdong four meeting dried orange peels of 5 years, dry, pulverize, obtain dried orange peel dry powder; Dried orange peel dry powder is adopted to steam distillation distillation, and gained fraction extracted with diethyl ether, is extracted liquid; Extract is dried with anhydrous sodium sulfate, then reduced pressure concentration, reclaim ether, obtain dried orange peel essential oil;
Described clove oil is to prepare according to the following steps: cloves is dried, pulverized, obtain dry clove powder; Dry clove powder is adopted to steam distillation distillation, and gained fraction extracted with diethyl ether, is extracted liquid; Extract is dried with anhydrous sodium sulfate, then reduced pressure concentration, reclaim ether, obtain clove oil.
6. the apple vinegar beverage that a kind for the treatment of according to claim 1 and prevention are had the hiccups, is characterized in that: described sorosis honey is that sorosis honey is produced in Guangdong; Described lichee honey is that lichee honey is produced in Guangdong.
7. the preparation method of the apple vinegar beverage that a kind for the treatment of according to claim 1 and prevention are had the hiccups, it is characterized in that comprising following operating procedure: by said ratio, take the former vinegar of apple, fresh apple juice, Maoyanmei tea extract, dried orange peel essential oil, clove oil, sorosis honey, lichee honey, white sugar, Aspartame, citric acid, caramel colorant and potassium sorbate and be placed in blend tank, add pure water to dissolve, mix, then ultrahigh-temperature instant Biocidal treatment method carries out sterilization, canned, must to treat and prevent to have the hiccups apple vinegar beverage.
8. preparation method according to claim 7, is characterized in that: described ultrahigh-temperature instant Biocidal treatment method is sterilizing 3~5s under 115~120 ℃ of conditions of temperature.
CN201310025877.1A 2013-01-23 2013-01-23 Apple vinegar beverage for treating and preventing hiccups and preparation method thereof Expired - Fee Related CN103040065B (en)

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