Apple vinegar beverage that a kind for the treatment of and prevention are had the hiccups and preparation method thereof
Technical field
The invention belongs to the drink formula field, particularly a kind for the treatment of and prevention apple vinegar beverage of having the hiccups and preparation method thereof.
Background technology
Having the hiccups is hiccup, refers to gas superinverse from stomach, again and again utters a word between larynx, and sound is anxious and very brief, make us independently being the illness of feature, and be common phenomenon on the physiology.Have the hiccups and cause because diaphragmatic spasm shrinks.It shrinks at every turn reposefully, and our lung just sucks without a break; Because it is by the control of brain respiratory center, diaphram can be movable regularly, and our breathing can fully independently operate, and we are also often remembering how to breathe when not required.When having the hiccups, the contraction that diaphragm flesh be can't help, air is by in the rapid inspiration lung, and narrow suddenly in the crack among two vocal cords, thereby cause the strange sound.
The reason of having the hiccups has multiple, and the general state of an illness is not heavy, can disappear voluntarily.But also the sustainable long period of some case, become intractable and have the hiccups.This class present doctor trained in Western medicine of having the hiccups can't accurately be judged the concrete cause of disease clinically, also without good methods for the treatment of, therefore mainly adopts clinically the Chinese traditional treatment method.Doctor trained in Western medicine thinks because due to the diaphragmatic spasm, and can be divided into coldness in the stomach, stomach Qi upward reversal, the resistance of circulation of vital energy in the wrong direction phlegm, YANG deficiency of the spleen and stomach, deficiency of stomach-Yin etc. during Chinese medical discrimination.Intractable is had the hiccups and is mostly occurred at mid-aged population, can adopt looser medical treatment of tcm prescription belch.
Research finds that hiccup can be by stimulating particularly spreading out of or afferent nerve of diaphram of control respiratory muscle, and medullary substance maincenter etc. causes.Also have at present a lot of folkd therapies can cure hiccup, these methods all be based on principle of uniformity, and namely when carbon dioxide in the blood was assembled, hiccup just can stop.When holding the breath, gas concentration lwevel just can increase in the blood, and therefore available this principle is prevented hiccup.To a paper bag internal respiration, also can improve the level of carbon dioxide in the blood.Fast drinking-water, fast swallow rusk or trash ice can stimulate the vagus nerve that is sent and arranged stomach by brain, thereby hiccup is stopped.Also can come vagus nerve stimulation with the method for tractive tongue or the eyelid that gently rubs one's eyes gently.These methods are effective to most of hiccup patients.Additive method also comprises gastric lavage, electro photoluminescence nervus phrenicus, with little bougienage oesophagus etc., sucks and contains 5%CO
2Oxygen also can be effective, adversary's postoperative patient particularly, to diaphram pleurisy patient, using tight lower breast to drag can be helpful.Drug therapy to the continuation hiccup comprises hyoscine, amphetamine, prochlorperazine, chlorpromazine, phenobarbital or anesthetic etc.10~20 milligrams of metoclopramides, oral, every day 2~4 times, may be effectively to some patient, then the success rate of drug therapy still is difficult to determine.To bothersome intractable patient, the treatment on probation of available following methods: 1, a small amount of 0.5% procaine is done the nervus phrenicus sealing, should note avoiding respiration inhibition and pneumothorax; 2,10 milligrams of sublingual administrations of nifepine if still hiccup is more than in half an hour, can chases after and take 10 milligrams.But repeat administration should be above 100 milligrams in 24 hours; 3, important on the one hand, on the one hand acupuncture and moxibustion therapy comprises the treatment of type Treated with Point-injection Therapy and acupoint medicinal injection; 4, diaphragm pacing treatment intractable hiccup.But the drug therapy meeting produces certain toxic and side effect, and can't effect a radical cure persistent ailment, falls flat, in the urgent need to a kind of method simple and evident in efficacy.
Summary of the invention
In order to solve above-mentioned the deficiencies in the prior art part, primary and foremost purpose of the present invention is to provide a kind of apple vinegar beverage for the treatment of and preventing to have the hiccups.
Another object of the present invention is to provide the preparation method of above-mentioned apple vinegar beverage.
Purpose of the present invention realizes by following technical proposals: the apple vinegar beverage that a kind for the treatment of and prevention are had the hiccups, and this apple vinegar beverage is made by following raw material by mass percentage:
Above-mentioned apple vinegar beverage is more preferably by following raw material by mass percentage and makes:
Total acid in the former vinegar of described apple is counted mass percent 10.0~10.5% with malic acid, folate content 〉=120 μ gDFE/1000ml, biotin content 〉=90.0 μ g/1000ml, content of choline 〉=190.0mg/1000ml, vitamin A content 〉=600 μ gRE/1000ml, content of vitamin E 〉=12.00mg α-TE/1000ml, cobalamin content 〉=2.00 μ g/1000ml, Nicotinic Acid Content 〉=10.00mg/1000ml;
The mass content of dibydro myricetrin monomer component is 40~48% in the described Maoyanmei tea extract, and the mass content of myricetin monomer component is 4~4.2%;
The mass content of eugenol 〉=70% in the described clove oil;
The mass content of D-citrene is 10% in the described dried orange peel essential oil, and the mass content of beta-myrcene is 5~6%;
1-DNJ (DNJ) mass content 〉=0.5% in the described sorosis honey;
Lichee polysaccharide mass content 〉=10% in the described lichee honey.
Described white sugar, Aspartame, citric acid, caramel colorant and potassium sorbate are the delicatessen food level.
The former vinegar of described apple is to adopt Shandong product Fuji apple to carry out secondary fermentation to prepare, and fermentation temperature is controlled at 16~17 ℃ during fermentation; Described fresh apple juice is to adopt Shandong product Fuji apple to adopt to squeeze the juice to prepare with filter method.
Described Maoyanmei tea extract is to prepare according to the following steps: adopting the Maoyanmei tea of Hunan Zhangjiajie self-sow (is vine tea, ampelopsis grossedentata), adopt after drying water extraction method or ethanol extraction method to obtain the Maoyanmei tea extract, spray-dried method obtains the Maoyanmei tea extract again;
Described dried orange peel essential oil prepares according to the following steps: adopt storage period to surpass the Guangdong four meeting dried orange peels in 5 years, oven dry, pulverizing obtain dried orange peel dry powder; Dried orange peel dry powder is adopted the steam distillation distillation, and gained fraction extracted with diethyl ether is extracted liquid; Extract is carried out drying with anhydrous sodium sulfate, and reduced pressure concentration reclaims ether again, obtains the dried orange peel essential oil;
Described clove oil prepares according to the following steps: with cloves oven dry, pulverizing, obtain dry clove powder; Dry clove powder is adopted the steam distillation distillation, and gained fraction extracted with diethyl ether is extracted liquid; Extract is carried out drying with anhydrous sodium sulfate, and reduced pressure concentration reclaims ether again, obtains clove oil.
Described sorosis honey is that sorosis honey is produced in Guangdong; Described lichee honey is that lichee honey is produced in Guangdong.
The preparation method of the apple vinegar beverage that above-mentioned treatment and prevention are had the hiccups, comprise following operating procedure: take by weighing the former vinegar of apple, fresh apple juice, Maoyanmei tea extract, dried orange peel essential oil, clove oil, sorosis honey, lichee honey, white sugar, Aspartame, citric acid, caramel colorant and potassium sorbate by said ratio and place blend tank, adding pure water dissolves, mixes, then ultrahigh-temperature instant Biocidal treatment method (UHT) carries out sterilization, canned, namely get the apple vinegar beverage that treatment and prevention are had the hiccups.
Described ultrahigh-temperature instant Biocidal treatment method is the 3~5s that sterilizes under 115~120 ℃ of conditions of temperature.
Principle of the present invention is:
The former vinegar of apple: the smell of fruits is very sweet, sour-sweet soft, clearly good to eat, move one deeply, be rich in aspartic acid, serine, the aminoacid ingredient of the needed by human body such as tryptophan, and 10 several mineral materials such as phosphorus, iron, zinc, pectin, vitamin, mineral matter and ferment, a large amount of vitamin antioxidants, wherein VC content 10 times more than of apples especially.The present invention requires total acid content, folate content, biotin content, content of choline, vitamin A content, content of vitamin E, cobalamin content, the Nicotinic Acid Content in the former vinegar of apple to require the level that reaches certain, its objective is in order to impel each composition to play synergy, stop human body to be subject to suddenly overheated or pungent when stimulating, CO in the body inner blood
2Unexpected acute variation and cause hiccup.
The Maoyanmei tea extract: the Mao Yan certain kind of berries is the strange generation jewellery in the pure natural wild plant, the treasure-house of Compendium of Materia Medica has been enriched in its appearance, identify through many authoritative mechanisms of country, 17 seed amino acids and 14 kinds of trace elements of containing needed by human, contain thick protein 12.8~13.8%, general flavone content 7.5~8.3%, minimum 6%, issue health food certificate approval general flavone content 〉=6% by the Ministry of Public Health, its contained flavones can be got rid of human body harmful's acid and eliminate and ketoboidies, remove the blood dirt in the blood, regulate blood fat, reduce blood pressure, softening vessel effect is remarkable, the flavones energy sterilization anti-inflammatory that contains, clearing heat and detoxicating, the analgesia detumescence, blood fat-reducing blood pressure-decreasing, cough-relieving wets one's whistle, regulate and improve body immunity, to Staphylococcus aureus, first, beta streptococcus, Diplococcus pneumopniae, Bacillus influenzaes etc. have the very strong ability of killing.The purpose that the present invention uses this raw material and requires the content ratio of dibydro myricetrin and myricetin wherein to reach certain limit is to cause hiccup in order to stop the human body diaphragmatic spasm to shrink as far as possible.
The purpose of dried orange peel essential oil compatibility clove oil is to utilize it collaborative intestines and stomach are carried out gentleness stimulate, and promotes the secretion of digestive juice, gets rid of pneumatosis in the intestinal tube, strengthens the effectiveness of its fragrant stomach invigorating and the wind dispelling therapeutic method to keep the adverse qi flowing downward, simultaneously can excited cardiac muscle, make the slight contraction of blood vessel generation.
Lichee honey: honey of lychee flowers picks up from the nectar of lichee pistil, breath is full of fragrance, flavor is sweet, little band litchi tart flavour, existing honey clear and rich is but because added the distinctive composition of various honeybees oneself during Mel, so scorching without lichee, but it is special promotes the production of body fluid, beneficial blood, regulate the flow of vital energy, effect honey of lychee flowers bowl spares emergency, can five viscera settling.Prove that through modern medicine study distinctive active component is lichee polysaccharide in the honey of lychee flowers, digest and assimilate promoting that improve a poor appetite, calming soporific improves the human immunological competence.
Sorosis honey be with bee release in the mulberry tree garden and the honey that obtains, wherein the distinctive composition of existing common honey oneself has again distinctive active component 1-DNJ (DNJ) in the mulberry tree; 1-DNJ is a kind of alkaloid, has the multiple pharmacologically actives such as hypoglycemic, antitumor and antiviral.
The relative prior art of the present invention, have following advantage and beneficial effect: (1) the present invention fill a prescription rationally, takes full advantage of the characteristic that each raw material possesses separately, and rationally assembly makes its performance comprehensive therapeutic effect, very obvious to the result for the treatment of of having the hiccups through experimental verification, reached the purpose for the treatment of both principal and secondary aspect of disease; (2) processing and fabricating is simple, and taking convenience provides a kind of desirable food for preventing and treating to have the hiccups.
The specific embodiment
The present invention is described in further detail below in conjunction with embodiment, but embodiments of the present invention are not limited to this.
Employed each raw material sources of following examples are as follows:
1, the former vinegar of apple is to adopt Shandong product Fuji apple to carry out secondary fermentation to prepare, and fermentation temperature is controlled at 16~17 ℃ during fermentation; Total acid in the former vinegar of this apple is counted mass percent 10.0~10.5% with malic acid, folate content 〉=120 μ gDFE/1000ml, biotin content 〉=90.0 μ g/1000ml, content of choline 〉=190.0mg/1000ml, vitamin A content 〉=600 μ gRE/1000ml, content of vitamin E 〉=12.00mg α-TE/1000ml, cobalamin content 〉=2.00 μ g/1000ml, Nicotinic Acid Content 〉=10.00mg/1000ml.
2, fresh apple juice is that the product Fuji apple employing of employing Shandong is squeezed the juice and filter method prepares.
3, the Maoyanmei tea extract is to prepare according to the following steps: adopting the Maoyanmei tea of Hunan Zhangjiajie self-sow (is vine tea, ampelopsis grossedentata), adopt after drying water extraction method or ethanol extraction method to obtain the Maoyanmei tea extract, spray-dried method obtains the Maoyanmei tea extract again; The mass content of dibydro myricetrin monomer component is 40~48% in this Maoyanmei tea extract, and the mass content of myricetin monomer component is 4~4.2%.
4, the dried orange peel essential oil prepares according to the following steps: adopt storage period to surpass the Guangdong four meeting dried orange peels in 5 years, oven dry, pulverizing obtain dried orange peel dry powder; Dried orange peel dry powder is adopted the steam distillation distillation, and gained fraction extracted with diethyl ether is extracted liquid; Extract is carried out drying with anhydrous sodium sulfate, and reduced pressure concentration reclaims ether again, obtains the dried orange peel essential oil; The mass content of D-citrene is 10% in this dried orange peel essential oil, and the mass content of beta-myrcene is 5~6%.
5, clove oil prepares according to the following steps: with cloves oven dry, pulverizing, obtain dry clove powder; Dry clove powder is adopted the steam distillation distillation, and gained fraction extracted with diethyl ether is extracted liquid; Extract is carried out drying with anhydrous sodium sulfate, and reduced pressure concentration reclaims ether again, obtains clove oil; The mass content of eugenol 〉=70% in this clove oil.
6, described sorosis honey is that " the precious garden board of giving birth to " sorosis honey, the wherein mass content of 1-DNJ (DNJ) 〉=0.5% is produced in Guangdong; Described lichee honey is that " the precious garden board of giving birth to " lichee honey, the wherein mass content of lichee polysaccharide 〉=10% is produced in Guangdong.
Embodiment 1:
Take by weighing the former vinegar of apple of mass percent 5.350%, the fresh apple juice of mass percent 9.100%, the Maoyanmei tea extract of mass percent 0.100%, the dried orange peel essential oil of mass percent 0.075%, the clove oil of mass percent 0.175%, the sorosis honey of mass percent 0.225%, the lichee honey of mass percent 0.325%, the white sugar of mass percent 4.500%, the Aspartame of mass percent 0.025%, the citric acid of mass percent 0.130%, the potassium sorbate of the caramel colorant of mass percent 0.120% and mass percent 0.020% places blend tank, the pure water that adds mass percent 79.855% dissolves, mix, then adopt ultrahigh-temperature instant Biocidal treatment method (UHT) sterilization 5s under 115 ℃ of conditions of temperature, canned, namely get the apple vinegar beverage that the present invention's treatment and prevention are had the hiccups.
Embodiment 2
Take by weighing the former vinegar of apple of mass percent 5.391%, the fresh apple juice of mass percent 9%, the Maoyanmei tea extract of mass percent 0.1%, the dried orange peel essential oil of mass percent 0.074%, the clove oil of mass percent 0.170%, the sorosis honey of mass percent 0.220%, the lichee honey of mass percent 0.320%, the white sugar of mass percent 4.45%, the Aspartame of mass percent 0.020%, the citric acid of mass percent 0.120%, the potassium sorbate of the caramel colorant of mass percent 0.115% and mass percent 0.02% places blend tank, the pure water that adds mass percent 80% dissolves, mix, then adopt ultrahigh-temperature instant Biocidal treatment method (UHT) sterilization 3s under 120 ℃ of conditions of temperature, canned, namely get the apple vinegar beverage that the present invention's treatment and prevention are had the hiccups.
Embodiment 3
Take by weighing the former vinegar of apple of mass percent 5%, the fresh apple juice of mass percent 9.2%, the Maoyanmei tea extract of mass percent 0.12%, the dried orange peel essential oil of mass percent 0.076%, the clove oil of mass percent 0.180%, the sorosis honey of mass percent 0.230%, the lichee honey of mass percent 0.330%, the white sugar of mass percent 4.55%, the Aspartame of mass percent 0.030%, the citric acid of mass percent 0.140%, the potassium sorbate of the caramel colorant of mass percent 0.125% and mass percent 0.025% places blend tank, the pure water that adds mass percent 79.994% dissolves, mix, then adopt ultrahigh-temperature instant Biocidal treatment method (UHT) sterilization 4s under 118 ℃ of conditions of temperature, canned, namely get the apple vinegar beverage that the present invention's treatment and prevention are had the hiccups.
Embodiment 4
Take by weighing the former vinegar of apple of mass percent 5.5%, the fresh apple juice of mass percent 9.015%, the Maoyanmei tea extract of mass percent 0.11%, the dried orange peel essential oil of mass percent 0.075%, the clove oil of mass percent 0.170%, the sorosis honey of mass percent 0.225%, the lichee honey of mass percent 0.330%, the white sugar of mass percent 4.50%, the Aspartame of mass percent 0.020%, the citric acid of mass percent 0.120%, the potassium sorbate of the caramel colorant of mass percent 0.115% and mass percent 0.02% places blend tank, the pure water that adds mass percent 79.8% dissolves, mix, then adopt ultrahigh-temperature instant Biocidal treatment method (UHT) sterilization 5s under 116 ℃ of conditions of temperature, canned, namely get the apple vinegar beverage that the present invention's treatment and prevention are had the hiccups.
Embodiment 5
Treat 50 routine hiccup patients with the apple vinegar beverage that the treatment of embodiment 1 gained and prevention are had the hiccups, take every day 3 times, each 250ml; Wherein, man's 30 examples, woman's 20 examples, 20~60 years old age, 1~3 day hiccup duration, the result: (take hiccup in 3 days namely disappears produce effects, stop to treat rear without recurrence) 10 examples (20%), effectively (take hiccup in 3 days hour, but send out again subsequently, retreatment is still effective) 35 examples (70%), invalid (take hiccup in 3 days do not alleviate do not disappear) 5 examples (10%).
Embodiment 6
Treat 30 routine hiccup patients with the apple vinegar beverage that the treatment of embodiment 2 gained and prevention are had the hiccups, take every day 5 times, each 200ml; Wherein, man's 18 examples, woman's 12 examples, 18~60 years old age, 1~3 day hiccup duration, the result: (take hiccup in 3 days namely disappears produce effects, stop to treat rear without recurrence) 9 examples (30%), effectively (take hiccup in 3 days hour, but send out again subsequently, retreatment is still effective) 17 examples (56.7%), invalid (take hiccup in 3 days do not alleviate do not disappear) 4 examples (13.3%).
Above-described embodiment is the better embodiment of the present invention; but embodiments of the present invention are not restricted to the described embodiments; other any do not deviate from change, the modification done under Spirit Essence of the present invention and the principle, substitutes, combination, simplify; all should be the substitute mode of equivalence, be included within protection scope of the present invention.