CN103007158A - Traditional Chinese medicine for treating gastric cancer and preparation method of medicine - Google Patents

Traditional Chinese medicine for treating gastric cancer and preparation method of medicine Download PDF

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Publication number
CN103007158A
CN103007158A CN2012105825105A CN201210582510A CN103007158A CN 103007158 A CN103007158 A CN 103007158A CN 2012105825105 A CN2012105825105 A CN 2012105825105A CN 201210582510 A CN201210582510 A CN 201210582510A CN 103007158 A CN103007158 A CN 103007158A
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gastric cancer
chinese medicine
herba
fructus
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CN103007158B (en
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柳尧花
王丽华
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TONGYITANG PHARMACEUTICAL Co.,Ltd.
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柳尧花
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Abstract

The invention relates to a traditional Chinese medicine for treating a gastric cancer and a preparation method of the medicine, which belong to the technical field of traditional Chinese medicines. The traditional Chinese medicine for treating the gastric cancer comprises the following raw materials in parts by weight: 15-20 parts of vietnamese sophora root, 8-15 parts of houttuynia cordata, 5-10 parts of uniflower swisscentaury root, 10-18 parts of Chinese mosla herb, 8-16 parts of mangnolia officinalis, 5-10 parts of white hyacinth bean, 10-20 parts of silkworm excrement, 8-18 of purslane, 6-15 parts of malt, 10-18 parts of mume flower, 6-15 parts of yellow water lily, 8-15 parts of folium isatidis, 5-15 parts of evodia rutaecarpa, 8-12 parts of cubeb, 6-10 parts of galangal and 5-10 parts of rhizoma kaempferiae. The traditional Chinese medicine for treating the gastric cancer has the advantages of being capable of clearing away heat and toxic materials, strengthening spleen and stomach and warning spleen and stomach for dispelling cold, being reasonable in compatibility of medicines so as to bring out the best of the medicines, and being capable of enhancing the immunity of the organism, alleviating clinical symptoms, inhibiting the transfer and diffusion of cancer cells, reducing toxicity and enhancing efficacy, so that the life quality of patients is improved, and the life of the patients is prolonged.

Description

A kind of Chinese medicine for the treatment of gastric cancer and preparation method thereof
 
Technical field
The present invention relates to Chinese medicine for the treatment of gastric cancer and preparation method thereof, belong to technical field of Chinese medicines.
Background technology
Gastric cancer originates from the mucomembranous epithelial cell on the top layer of coat of the stomach, can betide each position (the gastric antrum pylorus district at most, take second place in the cardia district at the bottom of the stomach, body of stomach is less slightly) of stomach, can invade different depth and the range of coat of the stomach.Cancer is confined in the mucosa or the submucosal early gastric cancer that is called, and invades the flesh layer with dark or transfer to stomach and be called advanced gastric carcinoma with the exterior domain person.Naked eyes or gastroscopic observation gastric cancer have variform, as show shallow type, mass-type, ulcer type, infiltrative type, ulcerocancer (for the chronic gastric ulcer canceration).Microscope amplifying observation cancerous cell has polytype (histologic classification), such as adenocarcinoma (account for about 90%, comprise papillary adenocarcinoma, tubular adenocarcinoma, mucinous adenocarcinoma, signet-ring cell carcinoma), adenosquamous carcinoma, squamous cell carcinoma, undifferentiated carcinoma, carcinoid.The molecular structure of trickleer cancerous cell inside also has a lot of differences, and therefore, though all be called gastric cancer, even naked eyes are identical with microscopically finding type, individual character still has very big-difference, does not know the gastric cancer how many individual character uniquenesses are arranged actually at present.The annual new gastric cancer more than 100 ten thousand in the whole world, China accounts for 42%, and dead about 800,000, China accounts for 35%, is one of the highest country of incidence gastric cancer rate and mortality rate, and M ﹠ M all is that the world average level twice is many.2007, in front 10 cancers of China, (1) incidence gastric cancer rate was second, and mortality rate is the 3rd; (2) men and women's of M ﹠ M ratio is 2 to 1; (3) sickness rate in rural area is that 1.6 times of the city, the mortality rate in rural area are 1.9 times of city; (4) death/incidence rate (be equivalent to ill after the risk of dying of illness) is the 8th.The sickness rate of gastric cancer significantly raises along with the increase at age, and the peak age of morbidity is at 50 years old~80 years old, but presents year by year rejuvenation trend, and 19~35 years old patient's ratio rises to current 3.3% from 1.7% over 40 years in the gastric cancer.Generally all adopt operative therapy, chemotherapy, pharmacotherapy etc., but the said method effect is all very not obvious, but also with a lot of complication, is difficult for being accepted by the patient.
Summary of the invention
The object of the invention is to solve the weak point that above-mentioned prior art exists, thus provide a kind of curative effect obviously, have no side effect, can delay the Chinese medicine and preparation method thereof that PD speed prolongs the treatment gastric cancer in patient's life-span.
The present invention is achieved by the following technical solutions:
A kind of Chinese medicine for the treatment of gastric cancer, its special character are to be comprised of following raw material by weight ratio: Radix Sophorae Tonkinensis 15-20 part, Herba Houttuyniae 8-15 part, Radix Rhapontici 5-10 part, Herba Moslae 10-18 part, Cortex Magnoliae Officinalis 8-16 part, Semen Lablab Album 5-10 part, silkworm excrement 10-20 part, Herba Portulacae 8-18 part, Fructus Hordei Germinatus 6-15 part, FLOS MUME 10-18 part, duckweed meet careless 6-15 part, Folium Isatidis 8-15 part, Fructus Evodiae 5-15 part, Fructus Litseae 8-12 part, Rhizoma Alpiniae Officinarum 6-10 part, Rhizoma Kaempferiae 5-10 part;
The Chinese medicine of described treatment gastric cancer is comprised of following raw material by weight ratio: Radix Sophorae Tonkinensis 18-20 part, Herba Houttuyniae 10-15 part, Radix Rhapontici 8-10 part, Herba Moslae 12-18 part, Cortex Magnoliae Officinalis 8-14 part, Semen Lablab Album 8-10 part, silkworm excrement 15-20 part, Herba Portulacae 10-18 part, Fructus Hordei Germinatus 8-15 part, FLOS MUME 15-18 part, duckweed meet careless 8-15 part, Folium Isatidis 12-15 part, Fructus Evodiae 5-10 part, Fructus Litseae 10-12 part, Rhizoma Alpiniae Officinarum 8-10 part, Rhizoma Kaempferiae 6-10 part;
The Chinese medicine of described treatment gastric cancer is comprised of the raw material of following by weight optimal proportion: 20 parts of Radix Sophorae Tonkinensiss, 10 parts of Herba Houttuyniae, 8 parts of Radix Rhapontici, 12 parts of Herba Moslaes, 10 parts of Cortex Magnoliae Officinalis, 6 parts of Semen Lablab Albums, 12 parts of silkworm excrements, 15 parts of Herba Portulacaes, 12 parts in Fructus Hordei Germinatus, 15 parts of FLOS MUME, duckweed meet 8 parts of grass, 9 parts of Folium Isatidiss, 8 parts of Fructus Evodiaes, 10 parts of Fructus Litseae, 8 parts of Rhizoma Alpiniae Officinarums, 6 parts of Rhizoma Kaempferiaes;
A kind of preparation method for the treatment of the Chinese medicine of gastric cancer, its special character is may further comprise the steps:
(1) each raw material of Chinese medicine is taken by weighing by weight, soaked 2 hours;
(2) decoct to boiling with high heat first, used again slow fire boiling 2 hours;
(3) filter, take out medicinal residues;
(4) last medicinal residues are decocted with water 2 hours again, taking liquid is taken.
The effect of each Chinese medicinal components:
Radix Sophorae Tonkinensis: hardship, cold, relieve inflammation or internal heat detoxifcation;
Herba Houttuyniae: acrid in the mouth, tepor, heat-clearing and toxic substances removing;
Radix Rhapontici: bitter in the mouth is salty, heat-clearing and toxic substances removing, and Shujin is promoted blood circulation;
Herba Moslae: acrid-sweet flavor, warm in nature, relieving the exterior syndrome by diaphoresis, removing dampness for regulating stomach;
Cortex Magnoliae Officinalis: hardship, suffering, the circulation of qi promoting removing food stagnancy, dampness is except full;
Semen Lablab Album: sweet, tepor, spleen reinforcing and in;
Silkworm excrement: Gan Wen, dampness is dispeled the wind, regulating the function of the stomach to resolve the turbidity;
Herba Portulacae: cold in nature, sweet in the mouth acid, heat-clearing and toxic substances removing, diuretic damp eliminating;
Fructus Hordei Germinatus: sweet, flat, promote qi circulation digestion promoting, spleen benefiting and stimulating the appetite;
FLOS MUME: sour and astringent, flat, soothing liver-QI, stomach function regulating;
Duckweed meets grass: regulating the function of the stomach to resolve the turbidity;
Folium Isatidis: bitter in the mouth, cold, heat-clearing and toxic substances removing;
Fructus Evodiae: acrid in the mouth, temperature, warming the middle warmer and descending qi;
Fructus Litseae: acrid in the mouth, warm in nature, warming spleen and stomach for dispelling cold, promoting the circulation of QI to relieve pain;
Rhizoma Alpiniae Officinarum: suffering, heat, warming stomach for dispelling cold, pain relieving helps digestion;
Rhizoma Kaempferiae: suffering, temperature, the circulation of qi promoting warming middle-JIAO, pain relieving helps digestion.
The present invention treats the Chinese medicine of gastric cancer, can heat-clearing and toxic substances removing, invigorating the spleen and regulating the stomach, warming spleen and stomach for dispelling cold, and compatibility is reasonable, brings out the best in each other, enhancing human body immunity power is improved clinical symptoms, has suppressed transfer and the diffusion of cancerous cell, attenuation synergistic has improved Quality of Life, has prolonged patient's life-span.
The specific embodiment
Below provide the specific embodiment of the present invention, be used for formation of the present invention is described in further detail.
Embodiment 1
The Chinese medicine of present embodiment treatment gastric cancer, be comprised of following raw material by weight ratio: 15 parts of Radix Sophorae Tonkinensiss, 8 parts of Herba Houttuyniae, 5 parts of Radix Rhapontici, 10 parts of Herba Moslaes, 8 parts of Cortex Magnoliae Officinalis, 5 parts of Semen Lablab Albums, 10 parts of silkworm excrements, 8 parts of Herba Portulacaes, 6 parts in Fructus Hordei Germinatus, 10 parts of FLOS MUME, duckweed meet 6 parts of grass, 8 parts of Folium Isatidiss, 5 parts of Fructus Evodiaes, 8 parts of Fructus Litseae, 6 parts of Rhizoma Alpiniae Officinarums, 5 parts of Rhizoma Kaempferiaes.
Embodiment 2
The Chinese medicine of present embodiment treatment gastric cancer, be comprised of following raw material by weight ratio: 20 parts of Radix Sophorae Tonkinensiss, 15 parts of Herba Houttuyniae, 10 parts of Radix Rhapontici, 18 parts of Herba Moslaes, 16 parts of Cortex Magnoliae Officinalis, 10 parts of Semen Lablab Albums, 20 parts of silkworm excrements, 18 parts of Herba Portulacaes, 15 parts in Fructus Hordei Germinatus, 18 parts of FLOS MUME, duckweed meet 15 parts of grass, 15 parts of Folium Isatidiss, 15 parts of Fructus Evodiaes, 12 parts of Fructus Litseae, 10 parts of Rhizoma Alpiniae Officinarums, 10 parts of Rhizoma Kaempferiaes.
Embodiment 3
The Chinese medicine of present embodiment treatment gastric cancer, be comprised of following raw material by weight ratio: 18 parts of Radix Sophorae Tonkinensiss, 12 parts of Herba Houttuyniae, 8 parts of Radix Rhapontici, 14 parts of Herba Moslaes, 14 parts of Cortex Magnoliae Officinalis, 6 parts of Semen Lablab Albums, 15 parts of silkworm excrements, 14 parts of Herba Portulacaes, 10 parts in Fructus Hordei Germinatus, 14 parts of FLOS MUME, duckweed meet 8 parts of grass, 12 parts of Folium Isatidiss, 10 parts of Fructus Evodiaes, 10 parts of Fructus Litseae, 8 parts of Rhizoma Alpiniae Officinarums, 8 parts of Rhizoma Kaempferiaes.
Embodiment 4
The Chinese medicine of present embodiment treatment gastric cancer, be comprised of the raw material of following by weight optimal proportion: 20 parts of Radix Sophorae Tonkinensiss, 10 parts of Herba Houttuyniae, 8 parts of Radix Rhapontici, 12 parts of Herba Moslaes, 10 parts of Cortex Magnoliae Officinalis, 6 parts of Semen Lablab Albums, 12 parts of silkworm excrements, 15 parts of Herba Portulacaes, 12 parts in Fructus Hordei Germinatus, 15 parts of FLOS MUME, duckweed meet 8 parts of grass, 9 parts of Folium Isatidiss, 8 parts of Fructus Evodiaes, 10 parts of Fructus Litseae, 8 parts of Rhizoma Alpiniae Officinarums, 6 parts of Rhizoma Kaempferiaes;
The preparation method of the Chinese medicine of above-mentioned treatment gastric cancer may further comprise the steps:
(1) each raw material of Chinese medicine is taken by weighing by weight, soaked 2 hours;
(2) decoct to boiling with high heat first, used again slow fire boiling 2 hours;
(3) filter, take out medicinal residues;
(4) last medicinal residues are decocted with water 2 hours again, taking liquid is taken.
Test example:
Test patient totally 178 examples, male's 96 examples wherein, women's 82 examples all suffer from gastric cancer.
Criterion of therapeutical effect:
Produce effects: after 4 course of therapy, patient's gastrointestinal function recovers, and appetite is normal, and body constitution is recovered;
Take a turn for the better: patient's sx↓, gastrointestinal function takes a turn for the better, and it is normal that body constitution is recovered substantially;
Invalid: treatment is rear without any effect;
It below is therapeutic effect
The case sum Produce effects example number Routine number takes a turn for the better Invalid routine number Total effective rate
178 126 47 5 97.19%

Claims (4)

1. Chinese medicine for the treatment of gastric cancer, it is characterized in that being comprised of following raw material by weight ratio: Radix Sophorae Tonkinensis 15-20 part, Herba Houttuyniae 8-15 part, Radix Rhapontici 5-10 part, Herba Moslae 10-18 part, Cortex Magnoliae Officinalis 8-16 part, Semen Lablab Album 5-10 part, silkworm excrement 10-20 part, Herba Portulacae 8-18 part, Fructus Hordei Germinatus 6-15 part, FLOS MUME 10-18 part, duckweed meet careless 6-15 part, Folium Isatidis 8-15 part, Fructus Evodiae 5-15 part, Fructus Litseae 8-12 part, Rhizoma Alpiniae Officinarum 6-10 part, Rhizoma Kaempferiae 5-10 part.
2. described a kind of Chinese medicine for the treatment of gastric cancer according to claim 1, it is characterized in that being comprised of following raw material by weight ratio: Radix Sophorae Tonkinensis 18-20 part, Herba Houttuyniae 10-15 part, Radix Rhapontici 8-10 part, Herba Moslae 12-18 part, Cortex Magnoliae Officinalis 8-14 part, Semen Lablab Album 8-10 part, silkworm excrement 15-20 part, Herba Portulacae 10-18 part, Fructus Hordei Germinatus 8-15 part, FLOS MUME 15-18 part, duckweed meet careless 8-15 part, Folium Isatidis 12-15 part, Fructus Evodiae 5-10 part, Fructus Litseae 10-12 part, Rhizoma Alpiniae Officinarum 8-10 part, Rhizoma Kaempferiae 6-10 part.
3. described a kind of Chinese medicine for the treatment of gastric cancer according to claim 1, it is characterized in that being comprised of the raw material of following by weight optimal proportion: 20 parts of Radix Sophorae Tonkinensiss, 10 parts of Herba Houttuyniae, 8 parts of Radix Rhapontici, 12 parts of Herba Moslaes, 10 parts of Cortex Magnoliae Officinalis, 6 parts of Semen Lablab Albums, 12 parts of silkworm excrements, 15 parts of Herba Portulacaes, 12 parts in Fructus Hordei Germinatus, 15 parts of FLOS MUME, duckweed meet 8 parts of grass, 9 parts of Folium Isatidiss, 8 parts of Fructus Evodiaes, 10 parts of Fructus Litseae, 8 parts of Rhizoma Alpiniae Officinarums, 6 parts of Rhizoma Kaempferiaes.
4. described a kind of preparation method for the treatment of the Chinese medicine of gastric cancer according to claim 1-3 is characterized in that may further comprise the steps:
(1) each raw material of Chinese medicine is taken by weighing by weight, soaked 2 hours;
(2) decoct to boiling with high heat first, used again slow fire boiling 2 hours;
(3) filter, take out medicinal residues;
(4) last medicinal residues are decocted with water 2 hours again, taking liquid is taken.
CN201210582510.5A 2012-12-28 2012-12-28 Traditional Chinese medicine for treating gastric cancer and preparation method of medicine Active CN103007158B (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550633A (en) * 2013-11-20 2014-02-05 孙晶晶 Traditional Chinese medicine for treating stomach cancer of disharmony between liver and stomach type and preparation method thereof
CN105963552A (en) * 2016-05-11 2016-09-28 德施普科技发展温州有限公司 Traditional Chinese medicine composition for treating early gastric cancer with matching of argon knife and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101757566A (en) * 2010-04-07 2010-06-30 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composition for treating colon cancer and preparation method thereof
CN101757598A (en) * 2009-11-05 2010-06-30 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composition for treating advanced malignant liver tumor symptoms and preparation method thereof
CN101757567A (en) * 2010-04-07 2010-06-30 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composition for treating rectal cancer and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101757598A (en) * 2009-11-05 2010-06-30 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composition for treating advanced malignant liver tumor symptoms and preparation method thereof
CN101757566A (en) * 2010-04-07 2010-06-30 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composition for treating colon cancer and preparation method thereof
CN101757567A (en) * 2010-04-07 2010-06-30 泰一和浦(北京)中医药研究院有限公司 Traditional Chinese medicine composition for treating rectal cancer and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
叶丽红等: "周仲瑛教授的肿瘤观", 《中国中医药信息杂志》 *
苏丽等: "膏方治疗恶性肿瘤探赜", 《辽宁中医杂志》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103550633A (en) * 2013-11-20 2014-02-05 孙晶晶 Traditional Chinese medicine for treating stomach cancer of disharmony between liver and stomach type and preparation method thereof
CN103550633B (en) * 2013-11-20 2015-07-29 郝燕琴 A kind ofly treat Chinese medicine of liver-stomach disharmony type gastric cancer and preparation method thereof
CN105963552A (en) * 2016-05-11 2016-09-28 德施普科技发展温州有限公司 Traditional Chinese medicine composition for treating early gastric cancer with matching of argon knife and preparation method thereof

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