CN102973785B - Traditional Chinese medicine for treatment of diabetic cardiomyopathy - Google Patents
Traditional Chinese medicine for treatment of diabetic cardiomyopathy Download PDFInfo
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- CN102973785B CN102973785B CN201210440779.XA CN201210440779A CN102973785B CN 102973785 B CN102973785 B CN 102973785B CN 201210440779 A CN201210440779 A CN 201210440779A CN 102973785 B CN102973785 B CN 102973785B
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Abstract
The present invention discloses a traditional Chinese medicine for treatment of diabetic cardiomyopathy, including the following raw materials by weight: 12-15 parts of angelica sinensis, 8-9 parts of pseudo-ginseng, 7-8 parts of radix scrophulariae, 12-13 parts of honeysuckle, 11-15 parts of blackend swallowwort root, 12-18 parts of lucid ganoderma, 12-15 parts of semen lepidii, 8-10 parts of cortex mori, 6-8 parts of lignum dalbergiae odoriferae, 8-12 parts of rhizoma corydalis, 15-20 parts of codonopsis pilosula, 10-15 parts of licorice, 10-15 parts of radix ophiopogonis, and 20-30 parts of lodestone. The present invention takes natural Chinese medicines as raw materials, and makes use of the combined action of each medicine for treatment of coronary atherosclerotic heart disease. The medicine has no toxic side effects on human bodies, and is inexpensive and effective.
Description
Technical field
The present invention relates to a kind of Chinese medicine, relate in particular to a kind of Chinese medicine for the treatment of diabetic cardiopathy.
Background technology
Diabetic cardiopathy is the modal a kind of complication of diabetes, also be the one of the main reasons that diabetics is lethal, the diabetic cardiopathy of broad sense comprises coronary atherosclerotic heart disease, diabetic cardiomyopathy and diabetic heart autonomic neuropathy etc.The main clinical manifestation of diabetic cardiopathy has: the symptom such as tachycardia painless myocardial infarction, orthostatic hypotension, sudden death, arrhythmia during rest.
At present, the method of effectively not curing completely for the treatment of diabetic cardiopathy, topmost Therapeutic Method is that the long-acting Western medicine such as losartan or atenolol of taking maintain the state of an illness, Long-term taking medicine, and can not cure the state of an illness, patient is subject to the torment that disease is brought for a long time, and long-term taking Western medicine is larger to health side effect.
The traditional Chinese medical science is mainly being taked following several respects aspect treatment diabetic cardiopathy: (1) tonification class decoction for the treatment: atherosclerosis has weakened body resistance one side at differential diagnosis in tcm, righting is a main rule for the treatment of, wherein according to different internal organs location, select different therapy and formulas, as spleen reinforcing, the kidney invigorating, warming YANG etc.(2) blood-activating stasis-removing kind decoction for the treatment: blood circulation promoting and blood stasis dispelling is subject to people's attention very early, has done a large amount of research in this respect, and has disclosed related mechanism in conjunction with modern pharmacology research.Mainly contain lipid and invade profit; Platelet aggregation and thrombosis; Inflammatory reaction; The aspects such as vascular smooth muscle cell proliferation.(3) the dehumidifying class decoction for the treatment coronary heart disease of eliminating the phlegm: causing atherosclerotic principal element is Hyperlipemia, lipid metabolism imbalance.And hyperlipemia belongs to according to clinical manifestation that Chinese medicine expectorant is turbid, expectorant stasis of blood category.Pharmacological research shows, Huatan Formula medicine is reducing serum total cholesterol, low density lipoprotein, LDL and have remarkable effect aspect the formation of lipotropism speckle.
But no matter the traditional Chinese medical science or doctor trained in Western medicine, all do not have extraordinary effect for treatment diabetic cardiopathy, therefore requires further study.
Summary of the invention
The shortcoming existing in order to overcome above-mentioned prior art, the invention provides a kind of Chinese medicine for the treatment of diabetic cardiopathy, and this traditional Chinese medicine composition for treating diabetic cardiopathy determined curative effect is difficult for recurrence.
A kind of technical scheme for the treatment of the Chinese medicine of diabetic cardiopathy disclosed by the invention is, crude drug by following weight parts is made: 6～18 parts of Radix Angelicae Sinensis, 3～9 parts of Radix Notoginseng, 6～8 parts of Radix Scrophulariaes, 12～15 parts of Flos Loniceraes, 5～15 parts of Radix Cynanchi Atratis, 6～18 parts of Ganodermas, 10～15 parts of Semen Lepidii (Semen Descurainiae)s, 8～10 parts of Cortex Mori, 6～8 parts of Lignum Dalbergiae Odoriferaes, 8～12 parts of Rhizoma Corydalis, 15～20 parts of Radix Codonopsis, 1～20 part, Radix Glycyrrhizae, 5～20 parts of Radix Ophiopogonis, 10～30 parts of Magnetitums.
The invention also discloses a kind of Chinese medicine for the treatment of diabetic cardiopathy, crude drug by following weight parts is made: 12～15 parts of Radix Angelicae Sinensis, 8～9 parts of Radix Notoginseng, 7～8 parts of Radix Scrophulariaes, 12～13 parts of Flos Loniceraes, 11～15 parts of Radix Cynanchi Atratis, 12～18 parts of Ganodermas, 12～15 parts of Semen Lepidii (Semen Descurainiae)s, 8～10 parts of Cortex Mori, 6～8 parts of Lignum Dalbergiae Odoriferaes, 8～12 parts of Rhizoma Corydalis, 15～20 parts of Radix Codonopsis, 10～15 parts, Radix Glycyrrhizae, 10～15 parts of Radix Ophiopogonis, 20～30 parts of Magnetitums.
Collocation method: be decocted in water for oral dose, every day, potion, took at twice 30 days is a course for the treatment of.
The pharmacological action of each taste Chinese medicine:
Heart-nourishing Chinese angelica root is calmed the nerves, enhancing human body immunity power; Make blood clean, no longer sticky.
Radix Notoginseng nourshing blood and promoting blood circulation, blood-activating analgetic, the prosperous hemapodium of gas, tissue regeneration promoting blood and blood stasis removing blood, softening arteria coronaria blood vessel, reduces stasis blocking, makes blood supply of cardiac muscle full.
Radix Scrophulariae cures mainly epidemic febrile disease and nutrient blood, fever of the body, excessive thirst, crimson tongue, send out speckle, hectic fever due to YIN-deficiency chronic cough, fidgets due to deficiency not awake, Tianjin hinder constipation, order puckery dim-sighted, throat larynx swells and ache, scrofula sucutaneous nodule, skin sore.
Flos Lonicerae heat-clearing and toxic substances removing, wind-heat dissipating.
Radix Cynanchi Atrati heat clearing away, diuresis, the moon that nourishes heart, grows conception vessel.
Ganoderma the body resistance strengthening and constitution consolidating, benefiting QI and nourishing blood, makes blood clean and is rich in mobility, and this is the basis of improving blood supply of cardiac muscle.
Semen Lepidii (Semen Descurainiae) is stopped up lung for sputum, dyspnea and cough with excessive sputum, and fullness and distention in the chest and hypochondrium, must not put down sleepingly, and ascites pleural fluid is swollen, dysuria, pulmonary heart disease edema.
Cortex Mori is for dyspnea and cough due to lung-heat, edema distension oliguria, appearance skin edema.
Lignum Dalbergiae Odoriferae promoting flow of QI and blood, pain relieving, hemostasis, for epigastric pain, hypochondriac pain due to stagnation of liverQI, thoracic obstruction twinge, injury from falling down, traumatic hemorrhage.
Rhizoma Corydalis is invigorated blood circulation, promoting the circulation of QI, pain relieving.For the breast side of body, epigastric pain, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Radix Codonopsis has invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting, and for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst.
Radix Glycyrrhizae has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, and expelling phlegm for arresting cough, relieving spasm to stop pain, the effect of coordinating the actions of various ingredients in a prescription, for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire, for dryness of the lung dry cough, chronic consumptive disease cough, Tianjin wound is thirsty, vexed insomnia, interior-heat is quenched one's thirst, dryness of the intestine constipation, pharyngeal diphtheria; YIN nourishing and the production of body fluid promoting, nourishing the lung to arrest cough, for few thirsty, the dry cough spitting of blood in Tianjin of lung-stomach yin deficiency; The diseases such as the palpitation and being susceptible to fright of insufficiency of heart-YIN and calentura later stage consumption of body fluid by heat.
Magnetitum has suppressing the hyperactive liver and subsiding YANG; Calm the nerves relieving convulsion; Hearing-improing and eyesight improving; The effect of helping inspiration to relieve asthma.
The specific embodiment
With specific embodiment and clinical case, technical scheme of the present invention and curative effect are described below, but protection scope of the present invention is not limited to this:
The invention discloses a kind of Chinese medicine for the treatment of diabetic cardiopathy, crude drug by following weight parts is made: 6～18 parts of Radix Angelicae Sinensis, 3～9 parts of Radix Notoginseng, 6～8 parts of Radix Scrophulariaes, 12～15 parts of Flos Loniceraes, 5～15 parts of Radix Cynanchi Atratis, 6～18 parts of Ganodermas, 10～15 parts of Semen Lepidii (Semen Descurainiae)s, 8～10 parts of Cortex Mori, 6～8 parts of Lignum Dalbergiae Odoriferaes, 8～12 parts of Rhizoma Corydalis, 15～20 parts of Radix Codonopsis, 1～20 part, Radix Glycyrrhizae, 5～20 parts of Radix Ophiopogonis, 10～30 parts of Magnetitums.
Because diabetic cardiopathy comprises coronary atherosclerotic heart disease, diabetic cardiomyopathy and diabetic heart autonomic neuropathy etc., for different diseases, through long theoretical research and clinical practice, the present invention adjusts Chinese medicine formula, to adapt to different diseases.
Embodiment 1:
A kind of Chinese medicine for the treatment of coronary atherosclerotic heart disease, crude drug by following weight parts is made: 6～10 parts of Radix Angelicae Sinensis, 3～5 parts of Radix Notoginseng, 6～8 parts of Radix Scrophulariaes, 12～15 parts of Flos Loniceraes, 5～9 parts of Radix Cynanchi Atratis, 14～18 parts of Ganodermas, 10～13 parts of Semen Lepidii (Semen Descurainiae)s, 8～10 parts of Cortex Mori, 6～8 parts of Lignum Dalbergiae Odoriferaes, 10～12 parts of Rhizoma Corydalis, 15～20 parts of Radix Codonopsis, 5～20 parts, Radix Glycyrrhizae, 15～20 parts of Radix Ophiopogonis, 20～25 parts of Magnetitums.
Embodiment 2:
A kind of Chinese medicine for the treatment of diabetic cardiopathy, crude drug by following weight parts is made: 12～15 parts of Radix Angelicae Sinensis, 8～9 parts of Radix Notoginseng, 7～8 parts of Radix Scrophulariaes, 12～13 parts of Flos Loniceraes, 11～15 parts of Radix Cynanchi Atratis, 12～18 parts of Ganodermas, 12～15 parts of Semen Lepidii (Semen Descurainiae)s, 8～10 parts of Cortex Mori, 6～8 parts of Lignum Dalbergiae Odoriferaes, 8～12 parts of Rhizoma Corydalis, 15～20 parts of Radix Codonopsis, 10～15 parts, Radix Glycyrrhizae, 10～15 parts of Radix Ophiopogonis, 20～30 parts of Magnetitums.
Embodiment 3:
A kind of Chinese medicine for the treatment of diabetic heart autonomic neuropathy, crude drug by following weight parts is made: 15～18 parts of Radix Angelicae Sinensis, 6～9 parts of Radix Notoginseng, 6～8 parts of Radix Scrophulariaes, 14～15 parts of Flos Loniceraes, 10～14 parts of Radix Cynanchi Atratis, 6～9 parts of Ganodermas, 10～15 parts of Semen Lepidii (Semen Descurainiae)s, 8～10 parts of Cortex Mori, 6～8 parts of Lignum Dalbergiae Odoriferaes, 8～10 parts of Rhizoma Corydalis, 15～18 parts of Radix Codonopsis, 1～10 part, Radix Glycyrrhizae, 5～20 parts of Radix Ophiopogonis, 10～20 parts of Magnetitums.
The invention has the beneficial effects as follows: the present invention be take natural Chinese medicine as raw material, utilize the comprehensive function treatment diabetic cardiopathy of each taste medicine, human body is had no side effect, and cheap, determined curative effect.
1, clinical data: observe altogether 50 routine diabetic cardiopathy patients, male patient's 30 examples wherein, female patient's 20 examples; Coronary atherosclerotic heart disease 35 examples wherein, diabetic cardiomyopathy 8 examples, diabetic heart autonomic neuropathy 7 examples.Age 45-70 year, 59 years old mean age.
2, efficacy assessment standard:
(1) effective, by treating rear body constitution, strengthen, with it energetically, feeling of oppression and pain in the chest, palpitation and uneasiness, the heart beating disease such as overrun obviously alleviates, and the visible blood supply of cardiac muscle of electrocardiogram improves;
(2) effective, by treating rear body constitution, strengthen, with it energetically, feeling of oppression and pain in the chest, palpitation and uneasiness, the heart beating disease such as overrun alleviates to some extent;
(3) invalid, after treatment, symptom is unchanged.
3, Therapeutic Method: treatment group is taken medicine of the present invention, and every day is oral meal at twice 30 days was 1 course for the treatment of.
4, therapeutic outcome: at clinical this medicament of use, the 50 routine diabetic cardiopathy patients that take medicine, took medicine after two courses for the treatment of, and symptom is alleviated to some extent, takes medicine after 4 courses for the treatment of, and symptom is obviously improved.In the routine patient of clinical experiment 50, effective 38 examples, effective 10 examples, invalid 2 examples, total effective rate is 96%.
Application actual case:
Case one: Lee, man, 65 years old.Suffer from 8 years of diabetic cardiopathy, often, with uncomfortable in chest, the phenomenon of breathing hard, sometimes occur angina pectoris or pareordia sense of discomfort, the long-term taking multi-medicament state of an illness is all without being clearly better, start after being introduced to take medicine of the present invention, take medicine after 1 course for the treatment of, uncomfortable in chest, the symptoms such as phenomenon of breathing hard are clearly better, and take medicine after 2 months, the visible blood supply of cardiac muscle of electrocardiogram also obviously improves on inspection, the state of an illness is basicly stable, after 1 year, follows up a case by regular visits to, and the state of an illness is without recurrence.
Case two: Wang, female, 58 years old.Suffer from 5 years of diabetic cardiopathy, body constitution obviously dies down than before, and health is weak, often occurs feeling of oppression and pain in the chest, palpitation and uneasiness, the heart beating phenomenon such as overrun, take medicine of the present invention after 15 days, health has clear improvement than before, and feeling of oppression and pain in the chest, palpitation and uneasiness, the heart beating symptom such as overrun alleviates to some extent, takes medicine after 2 courses for the treatment of, health energetically, feeling of oppression and pain in the chest, palpitation and uneasiness, the heart beating symptom such as overrun disappears substantially, and drug withdrawal was followed up a case by regular visits to after 1 year, and the state of an illness is without recurrence.
Case three: gold certain, man, 56 years old.Suffer from 5 years of diabetic cardiopathy, often, with uncomfortable in chest, the phenomenon of breathing hard, sometimes occur angina pectoris, the long-term taking multi-medicament state of an illness is all without being clearly better, start after being introduced to take medicine of the present invention, take medicine after 1 course for the treatment of, uncomfortable in chest, the symptoms such as phenomenon of breathing hard are clearly better, and take medicine after 2 courses for the treatment of, the state of an illness is basicly stable, symptom disappears substantially, and drug withdrawal was followed up a case by regular visits to after 1 year, and the state of an illness is without recurrence.
Certainly; the present invention also can have other various embodiments; in the situation that not deviating from spirit of the present invention and essence thereof; those of ordinary skill in the art are when making according to the present invention various corresponding changes and distortion, but these corresponding changes and distortion all should belong to the protection domain of the appended claim of the present invention.
Claims (1)
1. a Chinese medicine for the treatment of diabetic cardiopathy, it is characterized in that, by the crude drug of following weight parts, made: 12～15 parts of Radix Angelicae Sinensis, 8～9 parts of Radix Notoginseng, 7～8 parts of Radix Scrophulariaes, 12～13 parts of Flos Loniceraes, 11～15 parts of Radix Cynanchi Atratis, 12～18 parts of Ganodermas, 12～15 parts of Semen Lepidii (Semen Descurainiae)s, 8～10 parts of Cortex Mori, 6～8 parts of Lignum Dalbergiae Odoriferaes, 8～12 parts of Rhizoma Corydalis, 15～20 parts of Radix Codonopsis, 10～15 parts, Radix Glycyrrhizae, 10～15 parts of Radix Ophiopogonis, 20～30 parts of Magnetitums.
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| CN105497344A (en) * | 2014-11-05 | 2016-04-20 | 汪兴东 | Traditional Chinese medicine for treating diabetic cardiomyopathy |
| CN104522493A (en) * | 2014-12-14 | 2015-04-22 | 周亮 | Health porridge for treating coronary atherosclerosis and preparation method of health porridge |
| CN108126101A (en) * | 2018-03-05 | 2018-06-08 | 中国人民解放军第四军医大学 | It is a kind of to be used to treat pharmaceutical preparation of diabetic cardiomyopathy and preparation method thereof |
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| CN102172378A (en) * | 2010-12-20 | 2011-09-07 | 北京绿源求证科技发展有限责任公司 | Traditional Chinese medicine for treating diabetic coronary heart disease |
| CN102274447B (en) * | 2011-08-27 | 2013-01-02 | 赵国辉 | Medicinal composition for treating diabetes |
| CN102389494A (en) * | 2011-09-03 | 2012-03-28 | 北京绿源求证科技发展有限责任公司 | Chinese medicine for treating diabetic heart diseases |
| CN102389502A (en) * | 2011-09-27 | 2012-03-28 | 北京绿源求证科技发展有限责任公司 | Chinese medicine for treating diabetic peripheral neuropathy |
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Effective date of registration: 20170724 Address after: 213300 Liyang City, Jiangsu Province Li Cheng Zhen Dong Street No. 182 Patentee after: Liyang Technology Development Center Address before: 213300, 168, Zhao Zhuang Road, Liyang Economic Development Zone, Changzhou, Jiangsu, Liyang Patentee before: Tianmuhu Health Product Co., Ltd., Liyang |