CN102961644A - Traditional Chinese medicine composition for treating hypomenorrhea - Google Patents
Traditional Chinese medicine composition for treating hypomenorrhea Download PDFInfo
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- CN102961644A CN102961644A CN2012104538616A CN201210453861A CN102961644A CN 102961644 A CN102961644 A CN 102961644A CN 2012104538616 A CN2012104538616 A CN 2012104538616A CN 201210453861 A CN201210453861 A CN 201210453861A CN 102961644 A CN102961644 A CN 102961644A
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Abstract
The invention discloses a traditional Chinese medicine composition for treating hypomenorrhea. The traditional Chinese medicine composition consists of the following traditional Chinese medicine raw materials in parts by weight: 15 parts of cuscuta chinensis, 15 parts of barbary wolfberry fruit, 9 parts of mistletoe, 15 parts of himalayan teasel root, 12 parts of eucommia ulmoides, 15 parts of prepared fleece flower root, 12 parts of Chinese yam, 10 parts of codonopsis pilosula, 15 parts of semen coicis, 12 parts of rehmannia glutinosa, 12 parts of Chinese angelica, 9 parts of white paeony root, 12 parts of rhizoma cyperi, 12 parts of radix bupleuri, 9 parts of red paeony root, 20 parts of salvia miltiorrhiza, 15 parts of caulis spatholobi, 15 parts of achyranthes bidentata amd 6 parts of prepared liquorice root. The traditional Chinese medicine has the basic effects of tonifying the kidney and replenishing essence and has the effects of relieving liver for smooth Qi and promoting blood circulation to remove blood stasis; and modern pharmacological studies prove that the reproductive axis of hypothalamus-hypophysis-ovary-uterus can be adjusted through the medicine, ovulation and luteal development are promoted, the ovary microcirculation is improved, and the medicine has the obvious effect of treating hypomenorrhea.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition for the treatment of hypomenorrhea.
Background technology
The menstrual cycle normal, through measuring obvious minimizing, even drop is namely clean; Or menstrual period shortened less than two days, also lack the person through amount, all be called " hypomenorrhea ".Hypomenorrhea is normal with delayed menstrual cycle and see that often the companion body heavily increases.Hypomenorrhea betides adolescence and the child-bearing period person can develop into amenorrhea, betides the climacteric person and then often enters menopause.Western medicine mainly is complementing estrogen, or female, progestogen cycle therapy, but cures the symptoms, not the disease, and symptom still occurs repeatedly after the drug withdrawal, and the long-term taking side effect is obvious.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of hypomenorrhea.
Its technical solution is:
A kind of Chinese medicine composition for the treatment of hypomenorrhea, its raw material of Chinese medicine by the following weight parts proportioning forms: 15 parts of Semen Cuscutae, 15 parts of Fructus Lycii, 9 parts of parasitisms, 15 parts of Radix Dipsacis, 12 parts of the Cortexs Eucommiae, 15 parts of Radix Polygoni Multiflori Preparata, 12 parts of Rhizoma Dioscoreaes, 10 parts of Radix Codonopsis, 15 parts of Semen Coiciss, 12 parts in Radix Rehmanniae Preparata, 12 parts of Radix Angelicae Sinensis, 9 parts of the Radix Paeoniae Albas, 12 parts of Rhizoma Cyperis, 12 parts of Radix Bupleuri, 9 parts of Radix Paeoniae Rubra, 20 parts of Radix Salviae Miltiorrhizaes, 15 parts of Caulis Spatholobis, 15 parts of Radix Achyranthis Bidentataes, 6 parts of Radix Glycyrrhizae Preparatas.
Above-mentioned Chinese medicine composition can be prepared into the multiple dosage forms such as decoction, pill, granule, capsule or tablet.Preparation method can be by the conventional production method of Chinese medicine preparation in the pharmaceutical field.
Preparation method such as decoction is as follows: the raw material of Chinese medicine of above-mentioned weight portion is put into drug-decocting appliance, add the clean water that meets drinking water standard, amount of water is to surpass liquid level 2～3cm as degree; Enter to fry in shallow oil and front above-mentioned raw material of Chinese medicine is soaked half an hour, make it fully moistening, fully fried in order to medicine juice; Then (suddenly) fire of useing force boils, and uses literary composition (little) fire instead again and decocts.Stop when decocting about 15 minutes, remove medicinal residues, get decoction.
Above-mentioned decoction further can be concentrated through high temperature for another example and to get thick paste, and then pill is made in the oven dry pulverizing.
Usage and dosage: begin to take medicine after menstruation is clean, oral each 10-20g, every day 3 times, withdraw menstrual period, and a menstrual cycle was 1 course for the treatment of.Serve on 3-5 the course for the treatment of.
Pharmacology of the present invention and beneficial effect are as follows:
The Chinese traditional treatment hypomenorrhea is generally started with from the kidney invigorating, and Fu Qing master's cloud " goes out all kidneys through water ", and kidney qi all plays important regulating action for menstruation through amount, cycle, and kidney qi is filled Sheng Caineng makes essence and blood abundance, sea of blood spill-over, normal through measuring.The treatment hypomenorrhea is sick, and Kidney-Nourishing is even more important.The present invention takes into account depressed liver-energy dispersing and QI regulating, blood circulation promoting and blood stasis dispelling take enriching kidney essence as basic side's medicine, and modern pharmacological research proves, we's medicine scalable hypothalamic-pituitary-ovarian-uterus Reproductive Axis, ovulation rate and corpus luteum are grown, and improve simultaneously the ovary microcirculation, and treatment hypomenorrhea effect is remarkable.
Analysis on TCM prescriptions: Semen Cuscutae acrid in the mouth, sweet in the side, temperature, nontoxic, enter the heart, liver, kidney three warps, the QI invigorating reinforcing YIN-essence, nourishing marrow and benefitting semen, the Fructus Lycii sweet in the mouth, property is flat, returns liver, kidney channel, the energy nourishing the liver and kidney, replenishing vital essence to improve eyesight, both equal nourishing the liver and kidney, beneficial essence are filled out marrow, are monarch drug altogether.Parasitism, Radix Dipsaci, Cortex Eucommiae invigorating the liver and kidney, bone and muscle strengthening, Radix Polygoni Multiflori Preparata, Radix Rehmanniae Preparata enrich and benefit essence and blood, the nourishing the liver of reinforcing the kidney, the auxiliary monarch drug of upper four flavors is strengthened the effect of enriching kidney essence, is ministerial drug altogether.Adjuvant drug: Chinese Angelica blood replonishing is invigorated blood circulation, the Radix Paeoniae Alba is nourished blood yin fluid astringing, and with the Radix Rehmanniae Preparata compatibility, get the meaning of SIWU TANG with blood-supplementing blood-nourishing; Rhizoma Dioscoreae spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the Radix Codonopsis replenishing QI to invigorate the spleen, Semen Coicis spleen invigorating eliminating dampness by diuresis, the three trains the benefit the foundation of acquired constitution, so that the essence and blood source is sufficient; Radix Bupleuri, Rhizoma Cyperi dispersing the stagnated live-QI to relieve the stagnation of QI, regulating QI to promote menstruation, on the one hand restriction medicine-feeding is bored with the power that nourish blood with the back on the other hand, the blood circulation promoting medicine compatibility can be strengthened nourshing blood and promoting blood circulation in case too grow; Radix Paeoniae Rubra, Radix Salviae Miltiorrhizae removing heat from blood and promoting blood circulation, the warm property of restriction monarch-minister drug, Radix Achyranthis Bidentatae, Caulis Spatholobi promoting blood circulation to restore menstrual flow are adjuvant drug altogether; The Radix Glycyrrhizae Preparata coordinating the actions of various ingredients in a prescription is for making medicine.The top compatibility is played enriching kidney essence, depressed liver-energy dispersing and QI regulating, the merit of promoting blood circulation to restore menstrual flow altogether.
Be elaborated below by the therapeutic effect of clinical data to this medicine:
1. physical data:
Whole 260 routine patients are divided into 2 groups at random.Matched group 128 examples, 22～38 years old age, average (30.31 ± 3.53) year; Body weight 44～68kg, average (54.67 ± 6.33) kg; Menstrual cycle 25～42 days, average (30.58 ± 3.62) sky; Treatment group 132 examples, 24～39 years old age, average (31.07 ± 4.00) year; Body weight 43～65kg, average (52.99 ± 7.03) kg; Menstrual cycle 26～40 days, average (31.23 ± 4.62) sky; Two groups of data compare there was no significant difference (P＞0.05), have comparability.
2. Therapeutic Method:
(1) matched group: adopt the artificial cycle therapy, menstruation rose on the 5th, and oral premarin 1.25mg serve on 25 every day 1 time, takes medicine last 5 days, added and used progesterone injection, 20mg, 1 intramuscular injection every day, simultaneously drug withdrawal.
(2) treatment group: oral Chinese medicine top decoction, begin to take medicine after menstruation is clean, every day, potion divided sooner or later twice decoction being taken warmly, and withdraw menstrual period, and a menstrual cycle was 1 course for the treatment of.Serve on 3-5 the course for the treatment of.
3. curative effect determinate standard:
(1) cures: recover normal through amount, keep more than 3 months;
(2) take a turn for the better: recover normal through the amount showed increased or through amount, but can not keep more than 3 months;
(3) invalid: menstrual cycle, unchanged through measuring.
4. result
Table 1
As can be seen from Table 1, traditional Chinese medicine composition for treating hypomenorrhea total effective rate of the present invention is 86.36%, the matched group total effective rate is 71.88%, treatment group obviously is better than matched group, and the cure rate for the treatment of group also is significantly improved than matched group, and two groups of comparing differences have significance (P＜0.05).
The specific embodiment
A kind of Chinese medicine composition for the treatment of hypomenorrhea, its raw material of Chinese medicine by the following weight parts proportioning forms: Semen Cuscutae 15 grams, Fructus Lycii 15 grams, parasitic 9 grams, Radix Dipsaci 15 grams, the Cortex Eucommiae 12 grams, Radix Polygoni Multiflori Preparata 15 grams, Rhizoma Dioscoreae 12 grams, Radix Codonopsis 10 grams, Semen Coicis 15 grams, Radix Rehmanniae Preparata 12 grams, Radix Angelicae Sinensis 12 grams, the Radix Paeoniae Alba 9 grams, Rhizoma Cyperi 12 grams, Radix Bupleuri 12 grams, Radix Paeoniae Rubra 9 grams, Radix Salviae Miltiorrhizae 20 grams, Caulis Spatholobi 15 grams, Radix Achyranthis Bidentatae 15 grams, Radix Glycyrrhizae Preparata 6 grams.
Chinese medicine composition can be prepared into the multiple dosage forms such as decoction, pill, granule, capsule or tablet.Preparation method can be by the conventional production method of Chinese medicine preparation in the pharmaceutical field.
Claims (1)
1. a Chinese medicine composition for the treatment of hypomenorrhea is characterized in that it is comprised of the raw material of Chinese medicine of following weight parts proportioning: 15 parts of Semen Cuscutae, 15 parts of Fructus Lycii, 9 parts of parasitisms, 15 parts of Radix Dipsacis, 12 parts of the Cortexs Eucommiae, 15 parts of Radix Polygoni Multiflori Preparata, 12 parts of Rhizoma Dioscoreaes, 10 parts of Radix Codonopsis, 15 parts of Semen Coiciss, 12 parts in Radix Rehmanniae Preparata, 12 parts of Radix Angelicae Sinensis, 9 parts of the Radix Paeoniae Albas, 12 parts of Rhizoma Cyperis, 12 parts of Radix Bupleuri, 9 parts of Radix Paeoniae Rubra, 20 parts of Radix Salviae Miltiorrhizaes, 15 parts of Caulis Spatholobis, 15 parts of Radix Achyranthis Bidentataes, 6 parts of Radix Glycyrrhizae Preparatas.
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| CN201210453861.6A CN102961644B (en) | 2012-11-13 | 2012-11-13 | Traditional Chinese medicine composition for treating hypomenorrhea |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103721237A (en) * | 2014-01-09 | 2014-04-16 | 孙胜波 | Traditional Chinese medicine composition for treating hypomenorrhea |
| CN104491622A (en) * | 2014-12-24 | 2015-04-08 | 周连才 | Pharmaceutical composition for treating delayed menstrual cycle |
| CN105343413A (en) * | 2015-12-14 | 2016-02-24 | 青岛麦瑞特医药技术有限公司 | Medicine preparation for treating liver stagnation and qi stagnation type hypomenorrhea |
| CN105362682A (en) * | 2015-11-25 | 2016-03-02 | 张立 | External-use medicine for treating hypomenorrhea |
| CN105362698A (en) * | 2015-12-18 | 2016-03-02 | 陈远征 | Medicine preparation for treating scanty menstruation after artificial abortion operation |
| CN105412466A (en) * | 2016-01-11 | 2016-03-23 | 青岛辰达生物科技有限公司 | Pharmaceutic preparation for treating endometrial impairment type hypomenorrhea |
| CN105434879A (en) * | 2015-12-28 | 2016-03-30 | 刘树芹 | Pharmaceutical preparation for hypomenorrhea caused by intrauterine adhesion |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1336219A (en) * | 2001-08-21 | 2002-02-20 | 徐凤玉 | Gynopathy treating traditional Chinese medicine |
| CN101732683A (en) * | 2009-12-25 | 2010-06-16 | 卢速江 | Chinese medicinal preparation for treating facial chloasma and preparation method thereof |
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2012
- 2012-11-13 CN CN201210453861.6A patent/CN102961644B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1336219A (en) * | 2001-08-21 | 2002-02-20 | 徐凤玉 | Gynopathy treating traditional Chinese medicine |
| CN101732683A (en) * | 2009-12-25 | 2010-06-16 | 卢速江 | Chinese medicinal preparation for treating facial chloasma and preparation method thereof |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103721237A (en) * | 2014-01-09 | 2014-04-16 | 孙胜波 | Traditional Chinese medicine composition for treating hypomenorrhea |
| CN104491622A (en) * | 2014-12-24 | 2015-04-08 | 周连才 | Pharmaceutical composition for treating delayed menstrual cycle |
| CN105362682A (en) * | 2015-11-25 | 2016-03-02 | 张立 | External-use medicine for treating hypomenorrhea |
| CN105343413A (en) * | 2015-12-14 | 2016-02-24 | 青岛麦瑞特医药技术有限公司 | Medicine preparation for treating liver stagnation and qi stagnation type hypomenorrhea |
| CN105362698A (en) * | 2015-12-18 | 2016-03-02 | 陈远征 | Medicine preparation for treating scanty menstruation after artificial abortion operation |
| CN105434879A (en) * | 2015-12-28 | 2016-03-30 | 刘树芹 | Pharmaceutical preparation for hypomenorrhea caused by intrauterine adhesion |
| CN105412466A (en) * | 2016-01-11 | 2016-03-23 | 青岛辰达生物科技有限公司 | Pharmaceutic preparation for treating endometrial impairment type hypomenorrhea |
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Inventor after: Chen Weiai Inventor after: Liu Xiaoyan Inventor after: Yuan Yuan Inventor before: Chen Weiai Inventor before: Liu Xiaoyan |
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Free format text: CORRECT: INVENTOR; FROM: CHEN WEIAI LIU XIAOYAN TO: CHEN WEIAI LIU XIAOYAN YUAN YUAN |
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