CN104324243A - Traditional Chinese medicine preparation for treating female menopause insomnia - Google Patents

Traditional Chinese medicine preparation for treating female menopause insomnia Download PDF

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CN104324243A
CN104324243A CN201410700510.XA CN201410700510A CN104324243A CN 104324243 A CN104324243 A CN 104324243A CN 201410700510 A CN201410700510 A CN 201410700510A CN 104324243 A CN104324243 A CN 104324243A
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poria
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陈富强
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    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating female menopause insomnia. The traditional Chinese medicine preparation is prepared from the following medicinal materials in parts by weight: 15 parts of codonopsis pilosula, 15 parts of bighead atractylodes rhizome, 10 parts of albizia flower, 12 parts of Radix Ophiopogonis, 15 parts of spina date seed, 30 parts of tuber fleeceflower stem, 15 parts of camel fat, 9 parts of Semen Nigellae, 12 parts of rhizoma anemarrhenae, 9 parts of Poria cocos, 9 parts of poria with hostwood, 9 parts of liquorice, 6 parts of pine leaf, 7 parts of Satyrium nepalensis, 8 parts of Rubia Linn and 5 parts of Arabian jasmine flower distillate. The clinical experiment proves that proper medicinal materials and ratios thereof are selected, and the traditional Chinese medicine preparation has the effects of reinforcing qi and nourishing blood, tonifying spleen and nourishing heart, soothing liver-qi stagnation and regulating Yin-Yang, is extremely high in cure rate of treating the female menopause insomnia, is safe and does not have any toxic or side effect.

Description

A kind of Chinese medicine preparation for the treatment of Women’s climacteric insomnia
Technical field
The present invention relates to a kind of Chinese medicine preparation, be specifically related to a kind of Chinese medicine preparation for the treatment of Women’s climacteric insomnia.
Background technology
Insomnia refer to have difficulty in going to sleep, sleep after the illness of easily waking up or lying awake all night, the traditional Chinese medical science claims " being insomnia ".The insomnia of western medical treatment Women’s climacteric adopts calm class medicine and the anxiolytic drugs such as stable usually.Because many patients worry that this type of medicine life-time service easily produces drug dependence, therefore wishing can the effective tcm methods treatment of application safety.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine preparation for the treatment of Women’s climacteric insomnia, it selects medical material compatibility suitable, meet Chinese medicine and modern medicine study theory, there is effect of benefiting QI and nourishing blood, invigorating spleen and nourishing heart, dispersing the stagnated live-QI to relieve the stagnation of QI, regulating YIN and YANG, the high and safe without toxic side effect for the treatment of Women’s climacteric insomnia cure rate.
In order to achieve the above object, the present invention is by the following technical solutions: a kind of Chinese medicine preparation for the treatment of Women’s climacteric insomnia, is prepared from by the medical material of following weight proportion: Radix Codonopsis 14 ~ 16 parts, the Rhizoma Atractylodis Macrocephalae 14 ~ 16 parts, Flos Albiziae 9 ~ 11 parts, Radix Ophiopogonis 11 ~ 13 parts, Semen Ziziphi Spinosae 14 ~ 16 parts, Caulis Polygoni Multiflori 28 ~ 32 parts, Adeps Cameli 14 ~ 16 parts, Semen Nigellae 8 ~ 10 parts, the Rhizoma Anemarrhenae 11 ~ 13 parts, 8 ~ 10 parts, Poria, Poria cum Radix Pini 8 ~ 10 parts, 8 ~ 10 parts, Radix Glycyrrhizae, illawarra mountain pine must 5 ~ 7 parts, long apart from blue 6 ~ 8 parts of bird foot, Rubiayunnanensis (Franch.) Dlels 7 ~ 9 parts, Liquor Flos Jasmini Sambac Distillata 0 ~ 6 part.
As preferably, be prepared from by the medical material of following weight proportion: Radix Codonopsis 14 ~ 16 parts, the Rhizoma Atractylodis Macrocephalae 14 ~ 16 parts, Flos Albiziae 9 ~ 11 parts, Radix Ophiopogonis 11 ~ 13 parts, Semen Ziziphi Spinosae 14 ~ 16 parts, Caulis Polygoni Multiflori 28 ~ 32 parts, Adeps Cameli 14 ~ 16 parts, Semen Nigellae 8 ~ 10 parts, the Rhizoma Anemarrhenae 11 ~ 13 parts, 8 ~ 10 parts, Poria, Poria cum Radix Pini 8 ~ 10 parts, 8 ~ 10 parts, Radix Glycyrrhizae, illawarra mountain pine palpus 5 ~ 7 parts, long distance bird foot blue 6 ~ 8 parts, Rubiayunnanensis (Franch.) Dlels 7 ~ 9 parts.
As preferably, be prepared from by the medical material of following weight proportion: Radix Codonopsis 14 ~ 16 parts, the Rhizoma Atractylodis Macrocephalae 14 ~ 16 parts, Flos Albiziae 9 ~ 11 parts, Radix Ophiopogonis 11 ~ 13 parts, Semen Ziziphi Spinosae 14 ~ 16 parts, Caulis Polygoni Multiflori 28 ~ 32 parts, Adeps Cameli 14 ~ 16 parts, Semen Nigellae 8 ~ 10 parts, the Rhizoma Anemarrhenae 11 ~ 13 parts, 8 ~ 10 parts, Poria, Poria cum Radix Pini 8 ~ 10 parts, 8 ~ 10 parts, Radix Glycyrrhizae, illawarra mountain pine palpus 5 ~ 7 parts, long blue 6 ~ 8 parts of distance bird foot, Rubiayunnanensis (Franch.) Dlels 7 ~ 9 parts, Liquor Flos Jasmini Sambac Distillata 4 ~ 6 parts.
As preferably, be prepared from by the medical material of following weight proportion: Radix Codonopsis 15 ~ 16 parts, the Rhizoma Atractylodis Macrocephalae 15 ~ 16 parts, Flos Albiziae 10 ~ 11 parts, Radix Ophiopogonis 12 ~ 13 parts, Semen Ziziphi Spinosae 15 ~ 16 parts, Caulis Polygoni Multiflori 30 ~ 32 parts, Adeps Cameli 15 ~ 16 parts, Semen Nigellae 9 ~ 10 parts, the Rhizoma Anemarrhenae 12 ~ 13 parts, 9 ~ 10 parts, Poria, Poria cum Radix Pini 9 ~ 10 parts, 9 ~ 10 parts, Radix Glycyrrhizae, illawarra mountain pine palpus 6 ~ 7 parts, long blue 7 ~ 8 parts of distance bird foot, Rubiayunnanensis (Franch.) Dlels 8 ~ 9 parts, Liquor Flos Jasmini Sambac Distillata 5 ~ 6 parts.
As preferably, be prepared from by the medical material of following weight proportion: Radix Codonopsis 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Flos Albiziae 10 parts, Radix Ophiopogonis 12 parts, Semen Ziziphi Spinosae 15 parts, Caulis Polygoni Multiflori 30 parts, Adeps Cameli 15 parts, Semen Nigellae 9 parts, the Rhizoma Anemarrhenae 12 parts, 9 parts, Poria, Poria cum Radix Pini 9 parts, 9 parts, Radix Glycyrrhizae, illawarra mountain pine palpus 6 parts, long blue 7 parts of distance bird foot, Rubiayunnanensis (Franch.) Dlels 8 parts, Liquor Flos Jasmini Sambac Distillata 5 parts.
A kind of preparation method for the treatment of the Chinese medicine preparation of Women’s climacteric insomnia, comprise the steps: that Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Flos Albiziae, Radix Ophiopogonis, Semen Ziziphi Spinosae, Caulis Polygoni Multiflori, Semen Nigellae, the Rhizoma Anemarrhenae, Poria, Poria cum Radix Pini, Radix Glycyrrhizae, illawarra mountain pine palpus, long distance bird foot orchid, Rubiayunnanensis (Franch.) Dlels are put into container by (1), add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) Adeps Cameli, Liquor Flos Jasmini Sambac Distillata are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of Women’s climacteric of the present invention insomnia.
The pharmacology analysis of each Chinese medicinal ingredients of the present invention is as follows:
Radix Codonopsis [nature and flavor] is sweet, flat.[return through] returns spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.
The Rhizoma Atractylodis Macrocephalae [nature and flavor] is bitter, sweet, temperature.[return through] returns spleen, stomach warp.[function cures mainly] invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, loose stool of having loose bowels, frequent fetal movement.
Flos Albiziae [source] this product is the dry inflorescence of leguminous plant Herba Albiziae.[nature and flavor] are sweet, flat.[return through] GUIXIN, Liver Channel.[function cures mainly] resolving stagnation for tranquilization.For irritability, melancholy insomnia.
Radix Ophiopogonis [source] this product is the dried root of liliaceous plant Radix Ophiopogonis (dwarf lilyturf).[nature and flavor] are sweet, and micro-hardship, is slightly cold.[return through] GUIXIN, lung, stomach warp.[function cures mainly] YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire.For dryness of the lung dry cough.Chronic consumptive disease is coughed, and Tianjin wound is thirsty, vexed insomnia, and interior-heat is quenched one's thirst, dryness of the intestine constipation; Pharyngeal diphtheria.
Semen Ziziphi Spinosae [source] this product is the dry mature seed of Rhamnaceae plant Ziziphi Spinosae.[nature and flavor] are sweet, sour, flat.[return through] returns liver, gallbladder, heart channel.[function cures mainly] tonifying liver, mind calming, arresting sweating, promotes the production of body fluid.For restlessness of asrhenia type and insomnia, palpitation with fear dreaminess, the empty hyperhidrosis of body, Tianjin wound is thirsty.
The rattan that Caulis Polygoni Multiflori [source] is polygonum multiflorum thunb or leaf bine stem.[nature and flavor] sweet micro-hardship, flat.[function cures mainly] nourishes heart, and calms the nerves, and dredging collateral dispels the wind.Control insomnia, impairment caused by overstrain, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.
The dry mature seed that Semen Nigellae [source] is ranunculaceae plant Semen Nigellae.[nature and flavor] sweet in the mouth, pungent, warm in nature.[function cures mainly] conditioning stomach-fire, aid digestion, teeth consolidating.Cure mainly dyspepsia, hepatalgia, liver function fails.
The dry rhizome of the Rhizoma Anemarrhenae [source] the liliaceous plant Rhizoma Anemarrhenae.[function cures mainly] clearing away heat-fire, promotes the production of body fluid and moisturizes.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Poria [nature and flavor] is sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
In the middle of Poria cum Radix Pini [source] poria cocos sclerotium, (Poria) entertains the part of Radix Pini massonianae or fine core person.Be cut into thin square more, solid.[nature and flavor] are sweet, flat.[function cures mainly] mind tranquilizing and the heart calming.Be applicable to the disease such as severe palpitation, insomnia forgetfulness.
Illawarra mountain pine palpus [source] medical material Ji Yuan: be the needle of pinaceae plant Pinus armandi Franch-P. Komavovii Lavl., Pinus taiwanesis, Pinus massoniana Lamb, Pollen pini thunbergii, Pinus tabuliformis, pinus yunnanensis faranch, Pinus koraiensis etc.[nature and flavor] are bitter; Warm in nature.[return through] heart; Spleen channel.[function cures mainly] dispeiling pathogenic wind and removing dampness; Killing parasites for relieving itching; Blood-promoting and mind-easing.Main air wets flaccidity syndrome and arthralgia syndrome; Foot gas; Eczema; Tinea; Rubella pruritus; Traumatic injury; Neurasthenia; Chronic nephritis; Hypertension.Preventing encephalitis, influenza.
Long long blue apart from bird foot apart from blue [source] the orchid family of bird foot, be used as medicine with tuber.[function cures mainly] the kidney invigorating is nourished heart.Cure mainly stomachache of suffering from a deficiency of the kidney, chronic nephritis, face foot edema.
Rubiayunnanensis (Franch.) Dlels [source] Rubiaceae Rubiayunnanensis (Franch.) Dlels, with all herbal medicine.[nature and flavor] are sweet, flat.[function cures mainly] is enriched blood and is invigorated blood circulation, expelling wind and removing dampness, softening the hard mass removing mass.Cure mainly anemia, traumatic injury, chronic gastritis, lipoma, menoxenia.
Adeps Cameli [source] is the glue juice fat in cameloid two-humped camel hunch.[nature and flavor] sweet in the mouth; Warm in nature.[return through] heart; Liver Channel.[function cures mainly] tonify deficiency is moisturized; Expelling wind and activating blood circulation; Subduing swelling and detoxicating.Main body asthenia is weary; Numbness of the skin skin pruritus; Muscles contraction is anxious; Sore swollen toxin; Anal fistula.
The distillate that Liquor Flos Jasmini Sambac Distillata [source] is the flower of Oleaceae plants jasmine.[nature and flavor] are light; Warm in nature.[return through] spleen channel.[function cures mainly] be amusing ward off dirty; Regulate the flow of vital energy; To improve looks damp flesh.The gas that main chest and diaphragm is old; And skin of can moistening.
Radix Glycyrrhizae [nature and flavor] is sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention has effect of benefiting QI and nourishing blood, invigorating spleen and nourishing heart, dispersing the stagnated live-QI to relieve the stagnation of QI, regulating YIN and YANG, the high and safe without toxic side effect for the treatment of Women’s climacteric insomnia cure rate.In side, Radix Codonopsis used, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae air making-up and spleen enlivening are with hemopoietic; Semen Ziziphi Spinosae, Caulis Polygoni Multiflori tranquilizing by nourishing the heart; Poria, Poria cum Radix Pini are reduced phlegm mind calming, calm the nerves to help Semen Ziziphi Spinosae; Radix Ophiopogonis, Rhizoma Anemarrhenae YIN nourishing and the production of body fluid promoting; Semen Ziziphi Spinosae joins Flos Albiziae energy tranquilizing by nourishing the heart, Cure for insomnia, and the sweet convergence the heart-yin of Semen Ziziphi Spinosae acid, the heart-yin must be received, and the mind rather obtains, and Herba Albiziae sweetness and bitterness can separate stagnation of liver-QI, and stagnation of liver-QI obtains Shu Ze and is without fear of an attack from the rear.Again with Semen Nigellae, illawarra mountain pine must, long, Rubiayunnanensis (Franch.) Dlels blue apart from bird foot help benefit mutually, moisturize with Adeps Cameli tonify deficiency more thereafter, Liquor Flos Jasmini Sambac Distillata is amusing and wards off dirty, all medicines share, and the yin nourishing that fills blood is with mind calming god, and spleen invigorating is as a means of change source, therefore Be very effective.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Take: Radix Codonopsis 15 grams, the Rhizoma Atractylodis Macrocephalae 15 grams, Flos Albiziae 10 grams, Radix Ophiopogonis 12 grams, Semen Ziziphi Spinosae 15 grams, Caulis Polygoni Multiflori 30 grams, Adeps Cameli 15 grams, Semen Nigellae 9 grams, the Rhizoma Anemarrhenae 12 grams, 9 grams, Poria, Poria cum Radix Pini 9 grams, 9 grams, Radix Glycyrrhizae, illawarra mountain pine palpus 6 grams, long apart from blue 7 grams of bird foot, Rubiayunnanensis (Franch.) Dlels 8 grams, Liquor Flos Jasmini Sambac Distillata 5 grams, be prepared by following processing step: (1) is by Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Flos Albiziae, Radix Ophiopogonis, Semen Ziziphi Spinosae, Caulis Polygoni Multiflori, Semen Nigellae, the Rhizoma Anemarrhenae, Poria, Poria cum Radix Pini, Radix Glycyrrhizae, illawarra mountain pine must, long blue apart from bird foot, Rubiayunnanensis (Franch.) Dlels puts into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract, again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract, finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract, merge three extracting solution, filter, obtain filtrate for subsequent use, (2) Adeps Cameli, Liquor Flos Jasmini Sambac Distillata are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use, (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of Women’s climacteric of the present invention insomnia.
Usage and dosage: oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 2 weeks, be 1 course for the treatment of, take 2 courses for the treatment of continuously.
Embodiment 2
Take: Radix Codonopsis 14 grams, the Rhizoma Atractylodis Macrocephalae 14 grams, Flos Albiziae 9 grams, Radix Ophiopogonis 11 grams, Semen Ziziphi Spinosae 14 grams, Caulis Polygoni Multiflori 28 grams, Adeps Cameli 14 grams, Semen Nigellae 8 grams, the Rhizoma Anemarrhenae 11 grams, 8 grams, Poria, Poria cum Radix Pini 8 grams, 8 grams, Radix Glycyrrhizae, illawarra mountain pine palpus 5 grams, long distance bird foot blue 6 grams, Rubiayunnanensis (Franch.) Dlels 7 grams.
The Chinese medicine preparation preparation method of the present embodiment is identical with embodiment 1.
Embodiment 3
Take: Radix Codonopsis 16 grams, the Rhizoma Atractylodis Macrocephalae 16 grams, Flos Albiziae 11 grams, Radix Ophiopogonis 13 grams, Semen Ziziphi Spinosae 16 grams, Caulis Polygoni Multiflori 32 grams, Adeps Cameli 16 grams, Semen Nigellae 10 grams, the Rhizoma Anemarrhenae 13 grams, 10 grams, Poria, Poria cum Radix Pini 10 grams, 10 grams, Radix Glycyrrhizae, illawarra mountain pine palpus 7 grams, long blue 8 grams of distance bird foot, Rubiayunnanensis (Franch.) Dlels 9 grams, Liquor Flos Jasmini Sambac Distillata 6 grams.
The Chinese medicine preparation preparation method of the present embodiment is identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of Women’s climacteric insomnia, select the routine clinical observation of Women’s climacteric insomniac 108 of diagnosis and treatment since 2010.All cases all meets the diagnostic criteria of female climacteric syndrome, and meets the diagnostic criteria of insomnia.The insomnia that eliminating physical disease or mental disorder symptom cause, had not taken the medicine such as ALprazolanic, clonazepam before all cases are medical.Patient is divided into treatment group and matched group two groups at random, treatment group 54 example, matched group 54 example.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes the Chinese medicinal capsule preparation obtained by the embodiment of the present invention 1, oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 2 weeks, be 1 course for the treatment of, take 2 courses for the treatment of continuously.
Matched group takes Medulla Junci decoct, oral, every day 2 times, each 1 time sooner or later, each 2, warm water delivery service after meal; Within 2 weeks, be 1 course for the treatment of, take 2 courses for the treatment of continuously.
3, efficacy determination:
(1) cure: sleep is normal, the length of one's sleep more than 6h, simultaneous phenomenon disappears.
(2) take a turn for the better: total sleep time extends more than 2h, but less than 6h, simultaneous phenomenon improves.
(3) do not heal: before sleeping as taking medicine, or extend the length of one's sleep less than 2h, symptom is without improvement.
4, result:
Select in the treatment group of the embodiment of the present invention 1 Chinese medicinal capsule, cure 41 examples, take a turn for the better 10 examples, and do not heal 3 examples, cure rate 75.9%, total effective rate 94.4%.
Cure 15 examples in matched group, take a turn for the better 24 examples, and do not heal 14 examples, cure rate 27.7%, total effective rate 72.2%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Obviously, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.

Claims (6)

1. treat the Chinese medicine preparation of Women’s climacteric insomnia for one kind, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Codonopsis 14 ~ 16 parts, the Rhizoma Atractylodis Macrocephalae 14 ~ 16 parts, Flos Albiziae 9 ~ 11 parts, Radix Ophiopogonis 11 ~ 13 parts, Semen Ziziphi Spinosae 14 ~ 16 parts, Caulis Polygoni Multiflori 28 ~ 32 parts, Adeps Cameli 14 ~ 16 parts, Semen Nigellae 8 ~ 10 parts, the Rhizoma Anemarrhenae 11 ~ 13 parts, 8 ~ 10 parts, Poria, Poria cum Radix Pini 8 ~ 10 parts, 8 ~ 10 parts, Radix Glycyrrhizae, illawarra mountain pine palpus 5 ~ 7 parts, long blue 6 ~ 8 parts of distance bird foot, Rubiayunnanensis (Franch.) Dlels 7 ~ 9 parts, Liquor Flos Jasmini Sambac Distillata 0 ~ 6 part.
2. a kind of Chinese medicine preparation for the treatment of Women’s climacteric insomnia according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Codonopsis 14 ~ 16 parts, the Rhizoma Atractylodis Macrocephalae 14 ~ 16 parts, Flos Albiziae 9 ~ 11 parts, Radix Ophiopogonis 11 ~ 13 parts, Semen Ziziphi Spinosae 14 ~ 16 parts, Caulis Polygoni Multiflori 28 ~ 32 parts, Adeps Cameli 14 ~ 16 parts, Semen Nigellae 8 ~ 10 parts, the Rhizoma Anemarrhenae 11 ~ 13 parts, 8 ~ 10 parts, Poria, Poria cum Radix Pini 8 ~ 10 parts, 8 ~ 10 parts, Radix Glycyrrhizae, illawarra mountain pine palpus 5 ~ 7 parts, long distance bird foot blue 6 ~ 8 parts, Rubiayunnanensis (Franch.) Dlels 7 ~ 9 parts.
3. a kind of Chinese medicine preparation for the treatment of Women’s climacteric insomnia according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Codonopsis 14 ~ 16 parts, the Rhizoma Atractylodis Macrocephalae 14 ~ 16 parts, Flos Albiziae 9 ~ 11 parts, Radix Ophiopogonis 11 ~ 13 parts, Semen Ziziphi Spinosae 14 ~ 16 parts, Caulis Polygoni Multiflori 28 ~ 32 parts, Adeps Cameli 14 ~ 16 parts, Semen Nigellae 8 ~ 10 parts, the Rhizoma Anemarrhenae 11 ~ 13 parts, 8 ~ 10 parts, Poria, Poria cum Radix Pini 8 ~ 10 parts, 8 ~ 10 parts, Radix Glycyrrhizae, illawarra mountain pine palpus 5 ~ 7 parts, long blue 6 ~ 8 parts of distance bird foot, Rubiayunnanensis (Franch.) Dlels 7 ~ 9 parts, Liquor Flos Jasmini Sambac Distillata 4 ~ 6 parts.
4. a kind of Chinese medicine preparation for the treatment of Women’s climacteric insomnia according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Codonopsis 15 ~ 16 parts, the Rhizoma Atractylodis Macrocephalae 15 ~ 16 parts, Flos Albiziae 10 ~ 11 parts, Radix Ophiopogonis 12 ~ 13 parts, Semen Ziziphi Spinosae 15 ~ 16 parts, Caulis Polygoni Multiflori 30 ~ 32 parts, Adeps Cameli 15 ~ 16 parts, Semen Nigellae 9 ~ 10 parts, the Rhizoma Anemarrhenae 12 ~ 13 parts, 9 ~ 10 parts, Poria, Poria cum Radix Pini 9 ~ 10 parts, 9 ~ 10 parts, Radix Glycyrrhizae, illawarra mountain pine palpus 6 ~ 7 parts, long blue 7 ~ 8 parts of distance bird foot, Rubiayunnanensis (Franch.) Dlels 8 ~ 9 parts, Liquor Flos Jasmini Sambac Distillata 5 ~ 6 parts.
5. a kind of Chinese medicine preparation for the treatment of Women’s climacteric insomnia according to claim 1, it is characterized in that, be prepared from by the medical material of following weight proportion: Radix Codonopsis 15 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Flos Albiziae 10 parts, Radix Ophiopogonis 12 parts, Semen Ziziphi Spinosae 15 parts, Caulis Polygoni Multiflori 30 parts, Adeps Cameli 15 parts, Semen Nigellae 9 parts, the Rhizoma Anemarrhenae 12 parts, 9 parts, Poria, Poria cum Radix Pini 9 parts, 9 parts, Radix Glycyrrhizae, illawarra mountain pine palpus 6 parts, long blue 7 parts of distance bird foot, Rubiayunnanensis (Franch.) Dlels 8 parts, Liquor Flos Jasmini Sambac Distillata 5 parts.
6. treat the preparation method of the Chinese medicine preparation of Women’s climacteric insomnia for one kind, it is characterized in that, comprise the steps: that Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Flos Albiziae, Radix Ophiopogonis, Semen Ziziphi Spinosae, Caulis Polygoni Multiflori, Semen Nigellae, the Rhizoma Anemarrhenae, Poria, Poria cum Radix Pini, Radix Glycyrrhizae, illawarra mountain pine palpus, long distance bird foot orchid, Rubiayunnanensis (Franch.) Dlels are put into container by (1), add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use;
(2) Adeps Cameli, Liquor Flos Jasmini Sambac Distillata are put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use;
(3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of Women’s climacteric of the present invention insomnia.
CN201410700510.XA 2014-11-28 2014-11-28 Traditional Chinese medicine preparation for treating female menopause insomnia Pending CN104324243A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104771524A (en) * 2015-04-22 2015-07-15 秦文官 Traditional Chinese medicine composition for treating neurasthenia and preparation method of traditional Chinese medicine composition
CN104799616A (en) * 2015-05-07 2015-07-29 东莞温思帝寝具科技有限公司 Traditional Chinese medicine mattress for enhancing health and promoting sleep

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004123667A (en) * 2002-10-07 2004-04-22 Hiroyuki Yoshimura Composition containing kale as active ingredient
CN1994423A (en) * 2006-12-24 2007-07-11 江国潮 Orally administered Chinese medicine for treating insomnia caused by deficiency of bladder-qi

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004123667A (en) * 2002-10-07 2004-04-22 Hiroyuki Yoshimura Composition containing kale as active ingredient
CN1994423A (en) * 2006-12-24 2007-07-11 江国潮 Orally administered Chinese medicine for treating insomnia caused by deficiency of bladder-qi

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
李清媛等: "酸枣仁汤加减治疗更年期失眠症疗效观察", 《中国实用医药》 *
马云枝等: "从气血论治失眠经验初探", 《中医研究》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104771524A (en) * 2015-04-22 2015-07-15 秦文官 Traditional Chinese medicine composition for treating neurasthenia and preparation method of traditional Chinese medicine composition
CN104799616A (en) * 2015-05-07 2015-07-29 东莞温思帝寝具科技有限公司 Traditional Chinese medicine mattress for enhancing health and promoting sleep

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Application publication date: 20150204