CN102949667A - Health-care product tablet for treating gastritis and preparation method thereof - Google Patents
Health-care product tablet for treating gastritis and preparation method thereof Download PDFInfo
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- CN102949667A CN102949667A CN 201210454970 CN201210454970A CN102949667A CN 102949667 A CN102949667 A CN 102949667A CN 201210454970 CN201210454970 CN 201210454970 CN 201210454970 A CN201210454970 A CN 201210454970A CN 102949667 A CN102949667 A CN 102949667A
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Abstract
The invention discloses a health-care product tablet for treating gastritis and a preparation method of the heal-care product tablet. The heal-care product tablet contains the following raw material medicinal components in parts by weight: 30 parts of radix pseudostellariae, 12 parts of radix astragali, 12 parts of rhiizoma dioscoreae, 12 parts of dendrobium, 12 parts of hyacinth bean, 30 parts of fructus hordei germinatus, 12 parts of radix salviae miltiorrhizae, 30 parts of cortex albiziae, 5 parts of glycyrrhiza and 3 parts of radix curcumae. The relative tablet in the invention has the effects of tonifying the spleen and nourishing the stomach and tonifying yin and activating collaterals, and is used for treating the symptoms such as atrophic gastritis and chronic superficial gastritis. A traditional Chinese medicinal composition of the tablet has the advantages of being fast to absorb, high in bioavailability, rapid in speed of reaching the effective blood concentration, accurate in qualification and stable in quality, free from dependency and the like, and conventional equipment can finish the production of the health-care product tablet.
Description
Technical field
The invention belongs to field of health care products, relate to a kind of troche of health products, particularly a kind of troche of health products that is used for the treatment of gastritis and preparation method thereof for the treatment of gastritis.
Background technology
Chronic atrophic gastritis also claims atrophic gastritis.Refer to the intrinsic body of gland atrophy of mucosa that causes after gastric mucosa surface suffers damage repeatedly, even disappear the common pathological change that thickens of muscular layer of mucosa.Because body of gland atrophy or disappearance, gastric mucosa has attenuation in various degree, and often with intestinal epithelial metaplasia, inflammatory reaction and atypical hyperplasia.This disease is one of digestive system common disease, and in China's population, the sickness rate of chronic gastritis is very high, and wherein atrophic gastritis accounts for 13.8% of the number examined.The many mistake by chronic superficial gastritis of chronic atrophic gastritis controlled or wrong treatment is transformed, and the minority atrophic gastritis can develop into gastric cancer.
Chronic atrophic gastritis is take protracted inflammation, long-term dyspepsia as feature.Main manifestations is abdominal distention, and then abdominal distention is more obvious for polyphagia a little, tastelessness, and gastral cavilty section dull pain is uncomfortable, and is tired, becomes thin poor appetite, anemia etc., the category of genus Chinese medicine " feeling of fullness ", " gastric abscess " etc.The pathogenic factor of chronic atrophic gastritis is illustrated so far not yet fully, it is generally acknowledged the associated that affects with immune factor, bile reflux, biological factor, medicine factor and relevant disease, the traditional Chinese medical science thinks and disorder of emotion, eating and drinking without temperance that weakness of the spleen and stomach, congenital defect etc. are relevant.In the treatment of primary disease, doctor trained in Western medicine all without the oral drugs of specially good effect, can be set about treatment from theory of Chinese medical science at present, uses the preparation of function of spleen and stomach regulating; The intestines and stomach modulators for treatment atrophic gastritis effect is fine, mainly is by the treatment viewpoint of the traditional Chinese medical science from integral body, treats according to the principle of determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.In recent years, the report of Chinese medicine chronic atrophic gastritis is a lot of. good folk prescription proved recipe is also arranged much, to improving subjective symptoms, promoting that the sick body rehabilitation is very helpful.The chronic atrophic gastritis course of disease is longer, makes slow progress, and often occurs the complication such as gastrorrhagia, gastric ulcer, anemia, gastric cancer in its pathological process, should cause medical personnel and patient's attention.At present, the existing treatment in market and prevention atrophic gastritis, a lot of products of chronic superficial gastritis are cured the symptoms, not the disease, and it is long to reach the effective blood drug concentration time, easily forms dependency, and toxic and side effects is large, and dosage is large.And product part of the present invention has taken above shortcoming, have absorb fast, bioavailability is high, reach that effective blood drug concentration speed is fast, no dependence, quantitatively accurately, the advantage such as steady quality.
Summary of the invention
The purpose of this invention is to provide a kind of troche of health products that is used for the treatment of gastritis and preparation method thereof, it has strengthening the spleen and nourishing the stomach, and the effect that tonifying YIN is active is used for atrophic gastritis, the diseases such as chronic superficial gastritis.
Technical scheme of the present invention is: design a kind of troche of health products that is used for the treatment of gastritis, it is characterized in that composition and weight proportion thereof that it contains crude drug are: 30 parts of Radix Pseudostellariaes, 12 parts of the Radixs Astragali, 12 parts of Rhizoma dioscoreaes, 12 parts of Herba Dendrobiis, 12 parts in Seem Lablab Album, 30 parts in Fructus Hordei Germinatus, 12 parts of Radix Salviae Miltiorrhizaes, 30 parts of Cortex Albiziaes, 5 parts in Radix Glycyrrhizae, 3 parts of Radix Curcumaes.
Described a kind of preparation method that is used for the treatment of the troche of health products of gastritis, it may further comprise the steps:
1) by following weight ratio weighting raw materials: 30 parts of Radix Pseudostellariaes, 12 parts of the Radixs Astragali, 12 parts of Rhizoma dioscoreaes, 12 parts of Herba Dendrobiis, 12 parts in Seem Lablab Album, 30 parts in Fructus Hordei Germinatus, 12 parts of Radix Salviae Miltiorrhizaes, 30 parts of Cortex Albiziaes, 5 parts in Radix Glycyrrhizae, 3 parts of Radix Curcumaes;
2) get above-mentioned ten flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, filtration is concentrated into relative density 1.10-1.20, temperature and is 80 ℃ thick paste, and spray drying is for subsequent use;
3) with step 2) with 32 parts of starch, 25 parts in dextrin, 5 parts of sucrose, mixing adds 85% ethanol.Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;
4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;
5) inner packing;
6) outer package, product inspection, warehouse-in.
Advantage of the present invention is: the Chinese medicinal tablet that contains among the present invention has strengthening the spleen and nourishing the stomach, and the effect that tonifying YIN is active is used for atrophic gastritis, the diseases such as chronic superficial gastritis.Wherein the monarch drug Radix Pseudostellariae is used for the lack of appetite asthenia of deficiency-weakness of spleen-QI, deficiency of stomach-Yin in the prescription.Energy strengthening the spleen gas, nourishing stomach-YIN.The Radix Astragali can significantly increase the total white blood cells in the blood, promotes phagocytic function and the sterilizing ability of neutrophilic granulocyte and macrophage.The administration of Astragalus membranaceus mouse stomach can obviously strengthen the activity of spleen NK cell, and this process and inducement interferon occur simultaneously.Astragalus polysaccharides also can stimulate the propagation of NK cell, and makes cyton become large.Rhizoma dioscoreae spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Herba Dendrobii is excitation to the Cavia porcellus intestinal tube that exsomatizes, and HERBA DENDROBII then is obvious inhibitory action; Extractum is excitation to rabbit intestinal tube low dose, and heavy dose is inhibitory action.The Fructus Hordei Germinatus food stagnation does not disappear, abdominal distention, and insufficiency of the spleen lack of appetite, newborn antiperspirant smoulders, distending pain of the breast, women's ablactation.The administration of Cortex Albiziae antiallergic Cortex Albiziae decoct rat oral gavage can suppress its peritoneum mast cell degranulation, and in vitro tests also has similar effect.The Cortex Albiziae decoct can obviously suppress antigen (horse serum) to sensitization process and the antibody production process of rat.Its effective ingredient seemingly is a heat-resisting water-soluble substances.Health product of the present invention have absorb fast, bioavailability is high, reach that effective blood drug concentration speed is fast, no dependence, quantitatively accurately, the advantage such as steady quality.
The specific embodiment
The invention will be further described below in conjunction with specific embodiment, but not as limitation of the present invention.The part that is not described in detail in the present embodiment is to adopt prior art, and industry standard or known approaches.
Embodiment 1
Described Chinese medicine preparation adopts following steps to make:
1) by following weight ratio weighting raw materials: 30 parts of Radix Pseudostellariaes, 12 parts of the Radixs Astragali, 12 parts of Rhizoma dioscoreaes, 12 parts of Herba Dendrobiis, 12 parts in Seem Lablab Album, 30 parts in Fructus Hordei Germinatus, 12 parts of Radix Salviae Miltiorrhizaes, 30 parts of Cortex Albiziaes, 5 parts in Radix Glycyrrhizae, 3 parts of Radix Curcumaes;
2) get above-mentioned ten the flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, the filtration, be concentrated into relative density 1.10-1.20(80 ℃) thick paste, spray drying, for subsequent use;
3) with step 2) with 32 parts of starch, 25 parts in dextrin, 5 parts of sucrose, mixing adds 85% ethanol.Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;
4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;
5) inner packing;
6) outer package, product inspection, warehouse-in.
The below is this Chinese medicine composition tablet (hereinafter to be referred as embodiment 1) the treatment atrophic gastritis that is used for the treatment of the troche of health products preparation of gastritis of the present invention, the clinical observation of chronic superficial gastritis
1 data and method
1.1 physical data
Select atrophic gastritis person 80 examples receive treatment voluntarily, male's 50 examples wherein, women's 30 examples, age 29-68 year, average 43.6 years old.Be divided at random treatment group 1, treatment group 2, treatment group 3, matched group, every group of 20 examples; Each organizes patient age symptom formation without significant difference, and disease time is the longest 5 years, the shortest January.Has comparability (P〉0.05).
1.2 Therapeutic Method
The treatment group Primary Care is consistent, and matched group is not taken medicine.The treatment group 1 usefulness embodiment of the invention 1, every day three times, one time 2,30 is a course for the treatment of.Treatment group 2 is used SANJIU WEITAI, and Nanfang Pharmaceutical Factory produces, one time 1 bag, 2 times on the one; Treatment group 3 gastritis recovering capsule, Tonghua letter is washed in a pan luxuriant Pharmaceutical production, every day 1 time, one time 8.
2 results
2.1 curative effect determinate standard
Cure: the main clinic symptoms such as epigastrium pain discomfort, acid regurgitation, belch, poor appetite disappear, and endoscopy gastric mucosa activeness pathological changes disappears or cicatrization is arranged, and bile reflux disappears, and Hp turns out cloudy; Produce effects: main clinic symptoms is significantly improved, and the endoscopy gastric mucosal lesions dwindles and surpasses 1/2, and bile reflux reduces, and obviously reduces before Hp treats or turns out cloudy; Invalid: main clinic symptoms is effectively alleviated, and endoscopy mucosa pathological changes dwindles 1/2 or not do not change even enlarge, and bile reflux is effectively improved, before Hp treats without significant change or increase the weight of.
2.2 therapeutic outcome
| Cure | Produce effects | Invalid | Effective percentage | |
| Contrast | 20 | 0 | ||
| Treatment group 1 | 11 | 8 | 1 | 95% |
| Treatment group 2 | 9 | 9 | 2 | 90% |
| Treatment group 3 | 8 | 9 | 3 | 85% |
3 discuss
Chronic gastritis (chronicgastritis) refers to chronic inflammatory disease or the atrophic lesion of the gastric mucosa that different pathogeny causes." gastric abscess " " stomach painful abdominal mass " " feeling of fullness " category that belongs to the traditional Chinese medical science.The sick position of stomachache has substantial connection at stomach with liver, spleen.Spleen is relevant with the stomach the exterior and the interior, altogether main lifting, so gastropathy relates in spleen more, the splenopathy also can reach stomach.Liver and stomach are the relations that wooden soil is taken advantage of gram, and irritability stasis certainly will restrain spleen and violate stomach, causes the mechanism of qi retardance, stomach-QI being unable to descend normally and be pain.Stomachache because of, i.e. so-called " stagnation of QI and blood may bring about pain ".The regulating the stomach to normalize QI pain relieving is the fundamentum for the treatment of gastropathy.Adopt Chinese medicine to import administration, invigorating the spleen and benefiting QI, heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling reach the healing purpose.And then illustrate that embodiment 1 affiliated prescription is reliably effective in this invention.
Claims (2)
1. troche of health products that is used for the treatment of gastritis is characterized in that composition and weight proportion thereof that it contains crude drug are: 30 parts of Radix Pseudostellariaes, 12 parts of the Radixs Astragali, 12 parts of Rhizoma dioscoreaes, 12 parts of Herba Dendrobiis, 12 parts in Seem Lablab Album, 30 parts in Fructus Hordei Germinatus, 12 parts of Radix Salviae Miltiorrhizaes, 30 parts of Cortex Albiziaes, 5 parts in Radix Glycyrrhizae, 3 parts of Radix Curcumaes.
2. a kind of preparation method that is used for the treatment of the troche of health products of gastritis according to claim 1, it may further comprise the steps:
1) by following weight ratio weighting raw materials: 30 parts of Radix Pseudostellariaes, 12 parts of the Radixs Astragali, 12 parts of Rhizoma dioscoreaes, 12 parts of Herba Dendrobiis, 12 parts in Seem Lablab Album, 30 parts in Fructus Hordei Germinatus, 12 parts of Radix Salviae Miltiorrhizaes, 30 parts of Cortex Albiziaes, 5 parts in Radix Glycyrrhizae, 3 parts of Radix Curcumaes;
2) get above-mentioned ten flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, filtration is concentrated into relative density 1.10-1.20, temperature and is 80 ℃ thick paste, and spray drying is for subsequent use;
3) with step 2) with 32 parts of starch, 25 parts in dextrin, 5 parts of sucrose, mixing adds 85% ethanol; Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;
4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;
5) inner packing;
6) outer package, product inspection, warehouse-in.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210454970 CN102949667A (en) | 2012-11-14 | 2012-11-14 | Health-care product tablet for treating gastritis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210454970 CN102949667A (en) | 2012-11-14 | 2012-11-14 | Health-care product tablet for treating gastritis and preparation method thereof |
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| CN102949667A true CN102949667A (en) | 2013-03-06 |
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| CN 201210454970 Withdrawn CN102949667A (en) | 2012-11-14 | 2012-11-14 | Health-care product tablet for treating gastritis and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877480A (en) * | 2014-03-04 | 2014-06-25 | 辽宁省中医药研究院 | Medicine for treating chronic gastritis and gastric mobility disorder and preparation method thereof |
| CN105477561A (en) * | 2016-01-11 | 2016-04-13 | 何婷婷 | Healthy beverage based on rhizoma dioscoreae |
-
2012
- 2012-11-14 CN CN 201210454970 patent/CN102949667A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103877480A (en) * | 2014-03-04 | 2014-06-25 | 辽宁省中医药研究院 | Medicine for treating chronic gastritis and gastric mobility disorder and preparation method thereof |
| CN103877480B (en) * | 2014-03-04 | 2017-06-23 | 辽宁省中医药研究院 | A kind of medicine for treating chronic gastritis and gastric motility disorder and preparation method thereof |
| CN105477561A (en) * | 2016-01-11 | 2016-04-13 | 何婷婷 | Healthy beverage based on rhizoma dioscoreae |
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Application publication date: 20130306 |