CN110339312A - One kind is for treating dermopathic external drug - Google Patents
One kind is for treating dermopathic external drug Download PDFInfo
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- CN110339312A CN110339312A CN201910770942.0A CN201910770942A CN110339312A CN 110339312 A CN110339312 A CN 110339312A CN 201910770942 A CN201910770942 A CN 201910770942A CN 110339312 A CN110339312 A CN 110339312A
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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Abstract
It is the present invention relates to drug field, in particular to a kind of for treating the field of dermopathic external drug；The present invention provides a kind of for treating dermopathic external drug, in parts by weight, be made of following raw materials: 12~18 parts of scutellaria, 10~15 parts of rhizoma atractylodis, 4~6 parts of semen coicis, 6~8 parts of Poria cocos, 6~9 parts of gentianae macrophyllae, 5~12 parts of semen plantaginis, 4~6 parts of radix achyranthis bidentatae, 10~12 parts of safflower, 10~12 parts of monkshood, 6~8 parts of the root of Chinese clematis, 5~8 parts of folium artemisiae argyi, 3~6 parts of pawpaw, 3~6 parts of Radix Glycyrrhizae, remaining is auxiliary material.The present invention active ingredients from traditional Chinese medicinal is extracted after in affected part hot compress, significant in efficacy, solving Western medicine mostly is analgesia and anti-inflammatory drugs respite pain, cannot treat dermopathic problem from the root.
Description
Technical field
It is the present invention relates to drug field, in particular to a kind of for treating the field of dermopathic external drug.
Background technique
Skin disease is common disease and frequently-occurring disease, and difficult disease is more, causes considerable distress to patient.Dermopathic clinical symptoms
In, show as primary lesion has macula, blood stasis, blister, tumour, suppurative, fungoid damage etc.；Show as secondary lesion
Have the scales of skin that peel off, dipping, erosion, ulcer, scar and moss etc..
Eczema as it is a kind of as caused by various internal and external factors, refractory and common allergic skin disease easy to recur it
One, with the raising and the accelerating rhythm of life of economic level, its disease incidence and consultation rate increase year by year in recent years.
The drug for the treatment of skin disease (such as eczema) used in the prior art, though there is certain curative effect in clinical application,
Every kind of drug specific aim is very strong, when diagnosing not clear enough, drug is selected to have great difficulty.And the dermatological department medicine listed at present
In object, much all contain hormone, be discontinued and send out, it is difficult to reach the dermopathic purpose of radical cure.
Summary of the invention
In order to solve the above problems existing in the present technology, the present invention provides one kind for treating dermopathic externally applied drug
Object.The technical scheme adopted by the invention is as follows:
One kind is used to treat dermopathic external drug, in parts by weight, is made of following raw materials:
10~15 parts of tribulus terrestris, 10~15 parts of Cortex Phellodendri, 10~15 parts of kuh-seng, 15~20 parts of purslane, 15~20 parts of Fructus Forsythiae,
15~20 parts of semen coicis of stir-fry, 10~15 parts of Poria cocos, 10~15 parts of rhizoma atractylodis macrocephalae, 15~20 parts of oldenlandia diffusa, 10~15 parts of rhizoma alismatis,
10~15 parts of coloured malt, 6~10 parts of Radix Glycyrrhizae, other auxiliary materials.
It is described to be used to treat dermopathic external drug, in parts by weight, it is made of following raw materials:
12 parts of tribulus terrestris, 12 parts of Cortex Phellodendri, 12 parts of kuh-seng, 16 parts of purslane, 16 parts of Fructus Forsythiae, 16 parts of semen coicis are fried, Poria cocos 12
Part, 12 parts of rhizoma atractylodis macrocephalae, 16 parts of oldenlandia diffusa, 12 parts of rhizoma alismatis, 12 parts of coloured malt, 8 parts of Radix Glycyrrhizae, other auxiliary materials.
Preferably, other described auxiliary materials are gelling agent, wetting agent, pH adjusting agent.
Preferably, the gelling agent is one or both of carbomer and cellulose derivative.
Preferably, the wetting agent is one of poly yamanashi esters, phospholipid and poloxamer or a variety of.
Preferably, the pH adjusting agent is triethanolamine.
It is a further object to provide a kind of for treating the preparation method of dermopathic external drug, the system
Preparation Method are as follows:
S1. it crushes after being separately dried tribulus terrestris, Fructus Forsythiae, oldenlandia diffusa, is extracted respectively with water after crushing, extracted
After take supernatant, tribulus terrestris extraction, forsythia suspense extraction, herba hedyotis diffusae extract are obtained after supernatant is concentrated；
S2. ethyl alcohol is separately added into after crushing Cortex Phellodendri, kuh-seng, rhizoma alismatis and Radix Glycyrrhizae to extract, and is filtered after extraction, by filtrate
It is phellodendron extract, shrubby sophora extract, Alisma extract and licorice after vacuum concentration；
S3. supercritical carbon dioxide extraction method is respectively adopted after crushing purslane, Poria cocos to extract, collects separating still
In extract, be purslane extract and tuckahoe extracts；
S4. semen coicis, coloured malt, rhizoma atractylodis macrocephalae will be fried to be extracted with water respectively, extracting solution is crossed into silica gel respectively after extraction
Column collects efflux, obtains frying Semen Coicis extract, Fructus Hordei Germinatus (parched) extract and Rhizoma Atractylodis Macrocephalae (parched) extract after concentration；
S5. each medicinal substances extract for weighing step S1~S4 preparation by weight, is dissolved in ethanol solution, sequentially adds gel
Agent, wetting agent adjust pH=5~7 with pH adjusting agent, are uniformly mixed, as treating dermopathic external drug.
Preferably, the mass fraction that ethanol solution is added is 75%, the additional amount of the ethanol solution is 100~
200mL。
Preferably, the gelling agent additional amount is 5~7g, and the wetting agent additional amount is 6~10g.
The drug application method are as follows: be used to treat dermopathic external drug by prepared by the present invention and be directly applied to suffer from
Place, massage is until absorb.Three times a day, a month as a course for the treatment of.
The present invention provides one kind for treating dermopathic external drug, and beneficial effect compared with the prior art is:
1. tribulus terrestris dispelling wind and arresting itching in formula used in the present invention, purslane is clearing heat and detoxicating, and Fructus Forsythiae is clearing heat and detoxicating, and all medicines are all
Based on clearing heat and detoxicating；Cortex Phellodendri heat-clearing and damp-drying drug, kuh-seng heat-clearing and damp-drying drug, desinsection diuresis, the two is closed and eliminating dampness is minister；Assistant is with invigorating the spleen benefit
Water subsides, rhizoma atractylodis macrocephalae invigorating the spleen for eliminating dampness, and making gas row, then aqueous pushes effectively, and oldenlandia diffusa is clearing heat and detoxicating, dampness removing is treating stranguria, and rhizoma alismatis is seeped
Wet Li Shui expels the heat-evil, and the two goes out damp and hot heresy with urine；Make with coloured malt stomach function regulating, Radix Glycyrrhizae coordinating the drug actions of a prescription.Quan Fangzhi is with invigorating the spleen benefit
Wet poison, dispelling wind and arresting itching are method, so that heresy is dispelled without hurting just, righting is without staying bandit.The latent square medication of tutor is also to embody " wind, wet, hot "
Heresy is the guidance of the interpretation of the cause, onset and process of an illness.
2. the external drug that the present invention uses is prepared by natural Chinese medicinal herb extraction, to the curative effect pole of skin disease eczema
It is good, and have no drug resistance, it is used according to illustration method, can fundamentally treat skin disease, make no longer to recur.
Specific embodiment
In order to which technical characteristic of the invention, purpose and beneficial effect are more clearly understood, now to of the present invention
Content carry out it is described further below.
Tribulus terrestris: bitter, pungent, flat.Return liver warp.Calming the liver is soothing the liver, dispelling pathogenic wind for improving eyesight, and relieve heat is antipruritic.Clinically it is used for liver-yang hyperactivity
Have a dizzy spell；The chest side of body of stagnation of liver qi not relax, cream close it is obstructed；Wind-heat cataract；Rubella itch.
Cortex Phellodendri has the effects of antibacterial, anti-eczema and cutitis, anti-oxidant, immunosupress, antiulcer.
Purslane has anti-inflammatory, analgesia, antibacterial, reducing blood lipid, hypoglycemic, antitumor, anti-oxidant, anti-aging, enhancing immune
Effect.
Fructus Forsythiae have antibacterial, it is antiviral, anti-inflammatory, adjust immune, resisting stress, antipyretic effect.
Osthole is one of principle active component of common cnidium fruit P.E, can inhibit passive cutaneous anaphylaxis,
And it wheezes to global tissue amine and has protective effect.
Radix Glycyrrhizae significantly inhibits Acute and chronic inflammation caused by a variety of proinflammatory agents, can inhibit the inflammation later period
Granulation tissue hyperplasia.
Poria cocos water extract, alkali carries object and alcohol extract can promote the phagocytic index and phagocytic percentage of macrophage, Fu
Siberian cocklebur polysaccharide has inhibiting effect to acute and chronic inflammation reaction.
Rhizoma alismatis: it is sweet, it trembles with fear.Li Shui, excreting dampness expel the heat-evil.Control difficult urination, edema swelling, vomiting, dysentery, phlegm retention, tinea pedis, leaching
Disease, hematuria.Qi-restoratives damages the exhaustion or lesion of the five internal organs, removes the five internal organs feeling of fullness, plays negative gas, and stopping leak essence quenches one's thirst, drenches drip, cuts off the water by bladder, three cokes.Kuh-seng
Semen coicis: slightly sweet flavor.The effect of invigorating the spleen, tonifying lung, heat-clearing, dampness removing.Except muscles and bones perverse trend is meciless, sharp stomach, consumer edema.
Control diarrhea, arthritis with fixed pain caused by dampness, muscle arteries and veins contraction, joint stuffiness, oedema, tinea pedis, consumptive lung disease, pulmonary abscess, acute appendicitis, stranguria with turbid discharge, leukorrhea.
Malt: promoting the circulation of qi helps digestion, spleen benefiting and stimulating the appetite, moves back newborn dissipate-swelling.For dyspepsia, abdominal distention, spleen eating less, newborn sweat is strongly fragrant
Product, swollen breasts, weaning women, Fructus Hordei Germinatus strengthening the spleen and stomach promote lactation.
Rhizoma Atractylodis Macrocephalae: bitter, sweet, warm.Returns spleen, stomach meridian.Air making-up and spleen enlivening, eliminate dampness and have diuretic effect, hidroschesis, miscarriage prevention.It is clinically used for deficiency of spleen-QI and stomach-QI
Anorexia and loose stool, fatigue and weakness；Edema due to deficiency of the spleen, phlegm retention；Exterior deficiency spontaneous perspiration；The threatened abortion of deficiency of the spleen causing weakness of QI.
In order to make it easy to understand, being carried out in detail to the present invention for treating dermopathic external drug below by specific embodiment
Thin description.It is important to note that specific embodiment is merely to explanation, it is clear that those skilled in the art can basis
Illustrate herein, carrying out various amendments or change, these modifications and variations to the present invention will also be included within the scope of the application.
Embodiment 1
One kind is used to treat dermopathic external drug, in parts by weight, is made of following raw materials:
12 parts of tribulus terrestris, 12 parts of Cortex Phellodendri, 12 parts of kuh-seng, 16 parts of purslane, 16 parts of Fructus Forsythiae, 16 parts of semen coicis are fried, Poria cocos 12
Part, 12 parts of rhizoma atractylodis macrocephalae, 16 parts of oldenlandia diffusa, 12 parts of rhizoma alismatis, 12 parts of coloured malt, 8 parts of Radix Glycyrrhizae, other auxiliary materials.
Other described auxiliary materials are carbomer, poly yamanashi esters, triethanolamine.
The preparation method comprises the following steps:
S1. it crushes after being separately dried tribulus terrestris, Fructus Forsythiae, oldenlandia diffusa, is extracted respectively with water after crushing, extracted
After take supernatant, tribulus terrestris extraction, forsythia suspense extraction, herba hedyotis diffusae extract are obtained after supernatant is concentrated；
S2. ethyl alcohol is separately added into after crushing Cortex Phellodendri, kuh-seng, rhizoma alismatis and Radix Glycyrrhizae to extract, and is filtered after extraction, by filtrate
It is phellodendron extract, shrubby sophora extract, Alisma extract and licorice after vacuum concentration；
S3. supercritical carbon dioxide extraction method is respectively adopted after crushing purslane, Poria cocos to extract, collects separating still
In extract, be purslane extract and tuckahoe extracts；
S4. semen coicis, coloured malt, rhizoma atractylodis macrocephalae will be fried to be extracted with water respectively, extracting solution is crossed into silica gel respectively after extraction
Column collects efflux, obtains frying Semen Coicis extract, Fructus Hordei Germinatus (parched) extract and Rhizoma Atractylodis Macrocephalae (parched) extract after concentration；
S5. each medicinal substances extract for weighing step S1~S4 preparation by weight is dissolved in the second that 150mL mass fraction is 75%
In alcoholic solution, 6g gelling agent, 8g wetting agent are sequentially added, pH=5~7 is adjusted with pH adjusting agent, is uniformly mixed, as controlling
Treat dermopathic external drug.
The drug application method are as follows: be used to treat dermopathic external drug by prepared by the present invention and be directly applied to suffer from
Place, massage is until absorb.Three times a day, a month as a course for the treatment of.
Embodiment 2
One kind is used to treat dermopathic external drug, in parts by weight, is made of following raw materials:
10 parts of tribulus terrestris, 10 parts of Cortex Phellodendri, 10 parts of kuh-seng, 15 parts of purslane, 15 parts of Fructus Forsythiae, 15 parts of semen coicis are fried, Poria cocos 10
Part, 10 parts of rhizoma atractylodis macrocephalae, 15 parts of oldenlandia diffusa, 10 parts of rhizoma alismatis, 10 parts of coloured malt, 6 parts of Radix Glycyrrhizae, other auxiliary materials.
The auxiliary material is cellulose derivative, phospholipid and triethanolamine.
The preparation method comprises the following steps:
S1. it crushes after being separately dried tribulus terrestris, Fructus Forsythiae, oldenlandia diffusa, is extracted respectively with water after crushing, extracted
After take supernatant, tribulus terrestris extraction, forsythia suspense extraction, herba hedyotis diffusae extract are obtained after supernatant is concentrated；
S2. ethyl alcohol is separately added into after crushing Cortex Phellodendri, kuh-seng, rhizoma alismatis and Radix Glycyrrhizae to extract, and is filtered after extraction, by filtrate
It is phellodendron extract, shrubby sophora extract, Alisma extract and licorice after vacuum concentration；
S3. supercritical carbon dioxide extraction method is respectively adopted after crushing purslane, Poria cocos to extract, collects separating still
In extract, be purslane extract and tuckahoe extracts；
S4. semen coicis, coloured malt, rhizoma atractylodis macrocephalae will be fried to be extracted with water respectively, extracting solution is crossed into silica gel respectively after extraction
Column collects efflux, obtains frying Semen Coicis extract, Fructus Hordei Germinatus (parched) extract and Rhizoma Atractylodis Macrocephalae (parched) extract after concentration；
S5. each medicinal substances extract for weighing step S1~S4 preparation by weight is dissolved in the second that 100mL mass fraction is 75%
In alcoholic solution, 5g gelling agent, 6g wetting agent are sequentially added, pH=5~7 is adjusted with pH adjusting agent, is uniformly mixed, as controlling
Treat dermopathic external drug.
The drug application method are as follows: be used to treat dermopathic external drug by prepared by the present invention and be directly applied to suffer from
Place, massage is until absorb.Three times a day, a month as a course for the treatment of.
Embodiment 3
One kind is used to treat dermopathic external drug, in parts by weight, is made of following raw materials:
15 parts of tribulus terrestris, 15 parts of Cortex Phellodendri, 15 parts of kuh-seng, 20 parts of purslane, 20 parts of Fructus Forsythiae, 20 parts of semen coicis are fried, Poria cocos 15
Part, 15 parts of rhizoma atractylodis macrocephalae, 20 parts of oldenlandia diffusa, 15 parts of rhizoma alismatis, 15 parts of coloured malt, 10 parts of Radix Glycyrrhizae, other auxiliary materials.
The auxiliary material is carbomer, poloxamer and triethanolamine.
The preparation method comprises the following steps:
S1. it crushes after being separately dried tribulus terrestris, Fructus Forsythiae, oldenlandia diffusa, is extracted respectively with water after crushing, extracted
After take supernatant, tribulus terrestris extraction, forsythia suspense extraction, herba hedyotis diffusae extract are obtained after supernatant is concentrated；
S2. ethyl alcohol is separately added into after crushing Cortex Phellodendri, kuh-seng, rhizoma alismatis and Radix Glycyrrhizae to extract, and is filtered after extraction, by filtrate
It is phellodendron extract, shrubby sophora extract, Alisma extract and licorice after vacuum concentration；
S3. supercritical carbon dioxide extraction method is respectively adopted after crushing purslane, Poria cocos to extract, collects separating still
In extract, be purslane extract and tuckahoe extracts；
S4. semen coicis, coloured malt, rhizoma atractylodis macrocephalae will be fried to be extracted with water respectively, extracting solution is crossed into silica gel respectively after extraction
Column collects efflux, obtains frying Semen Coicis extract, Fructus Hordei Germinatus (parched) extract and Rhizoma Atractylodis Macrocephalae (parched) extract after concentration；
S5. each medicinal substances extract for weighing step S1~S4 preparation by weight is dissolved in the second that 200mL mass fraction is 75%
In alcoholic solution, 7g gelling agent, 10g wetting agent are sequentially added, pH=5~7 is adjusted with pH adjusting agent, is uniformly mixed, is as used for
Treat dermopathic external drug.
The drug application method are as follows: be used to treat dermopathic external drug by prepared by the present invention and be directly applied to suffer from
Place, massage is until absorb.Three times a day, a month as a course for the treatment of.
For the contents of the present invention that illustrate being more clear, the present invention has carried out clinical trial, specific as follows:
One, clinical criteria
It is formulated referring to " People's Republic of China's traditional Chinese medicine industry standard and TCM Dermatology disease Standardization of diagnosis and curative effect "
Diagnostic criteria are as follows:
Morbidity is anxious, and skin lesion flush is scorching hot, and itch is without stopping, sepage stream juice.With restlessness and thirst, stool is dry, urinates short red.Tongue nature
Red, yellow tongue fur or yellow greasy, slippery or string are sliding.
Two, patient source
The selection major voluntary Patients with 300 Cases of outpatient service skin disease of this city, men and women each 150.Age 18-65 years old, course of disease 2-16
Year.
Three, administrated method:
It is used to treat dermopathic external drug by prepared by the present invention and is directly applied to affected part, massage is until absorb.Daily
Three times, a month as a course for the treatment of, and three courses for the treatment of are used continuously.
Points for attention: during 1. medications, giving up alcohol, and avoids the beverages such as strong tea, coffee.
It rests 2. more, pays attention to striking a proper balance between work and rest.
3. drinking more water, eat light food more.
Four, criterion of therapeutical effect:
1, effective: itch once in a while, when not medication, do not influence work and study.Erythema or dark red spot color are in pale red, are higher by
Skin is unobvious；Papule or phlysis color are micro- red, are distributed sparse, no phlysis；Rotten to the corn mild degree (dotted to be dispersed in)；Body fluid seeps
Mild degree out (dotted to be dispersed in, need to carefully see just can find out).
2, effectively: moderate itch (paroxysmal itch, when it is light when weight, influence sleep and live, need medication)；Moderate skin lesion
(erythema or dark red spot color are dark red, slightly higher skin out)；Papule or phlysis degree are that (color is light red, and distribution is slightly close, can for moderate
See papulo-vesicle)；Rotten to the corn degree moderate (point sheet, partially merge into each other)；Body fluid oozes out moderate (relatively more, easy drenched health
Paper).
3, invalid: severe itch (seriously affects sleep operation and study)；(color is scarlet, hence it is evident that is higher by skin for severe skin lesion
Skin)；Papule or phlysis degree are severe (color is redder, and distribution is closeer, and sporadically appear phlysis)；Rotten to the corn degree severe is (clearly
Sheet it is rotten to the corn)；Body fluid exudation is more, is in droplet shape.
4, occur dermatological conditions again after treating.
Obvious effective rate (%)=effective number/patient populations × 100%；
Efficient (%)=(effective number+efficiently individual quantity)/patient populations × 100%；
Recurrence rate (%)=recurrence number/patient populations × 100%.
Five, clinical treatment outcome:
It is counted and is calculated according to above-mentioned curative effect determinate standard, treatment results are as shown in table 1:
Curative effect of 1 present invention of table to dermatosis patient
| Number | Gender | It is effective | Effectively | In vain | Recurrence | Obvious effective rate | It is efficient | Recurrence rate |
| 150 | Male | 110 | 34 | 4 | 2 | 75% | 97% | 0.01% |
| 150 | Female | 101 | 45 | 3 | 1 | 68% | 98% | 0.01% |
As shown in Table 1, after patient has used three courses for the treatment of of drug of the invention according to administrated method, male's obvious effective rate reaches
75%, for women obvious effective rate up to 68%, men and women's obvious effective rate has difference related with men and women's constitution difference；In addition, no matter men and women, have
Efficiency has reached 97% or more, illustrates that drug of the invention is apparent for the curative effect of dermatosis patient；And recurrence rate only has
0.01%, illustrate that drug of the invention can eradicate skin disease.
Six, typical case
Patient 1: Wei, male, 38 years old, is diagnosed as eczema, administrated method according to the invention smears affected part, a course for the treatment of
Afterwards, symptom disappears and fully recovers, and does not recur in three months after drug withdrawal.
Patient 2: Zheng, male, and 21 years old.It is diagnosed as nettle rash, administrated method according to the invention is smeared, after one month, disease
Shape is substantially reduced, only remains some traces, continues to smear two weeks, and recovery from illness is not recurred in three months after drug withdrawal.
Patient 3: Xian, female, 44 years old, are diagnosed as piebald moss, have before and treated using Western medicine, although it is quick however
It recurs repeatedly, after smearing a course for the treatment of on time with drug of the invention later, symptom mitigates, after two courses for the treatment of, substantially fully recover,
It is not recurred after being discontinued 1 year.
Finally, it should be noted that the invention is not limited in any way for above embodiments.Those skilled in the art are come
It says, on the basis of the present invention, some modification and improvement can be made to it.Therefore, it is all without departing from theon the basis of the spirit of the present invention
Done it is any modify or improve, fall within the scope of the claimed invention within.
Claims (9)
1. one kind is for treating dermopathic external drug, which is characterized in that in parts by weight, be made of following raw materials:
10~15 parts of tribulus terrestris, 10~15 parts of Cortex Phellodendri, 10~15 parts of kuh-seng, 15~20 parts of purslane, 15~20 parts of Fructus Forsythiae, fry the heart of a lotus seed
15~20 parts of the seed of jog's tears, 10~15 parts of Poria cocos, 10~15 parts of rhizoma atractylodis macrocephalae, 15~20 parts of oldenlandia diffusa, 10~15 parts of rhizoma alismatis, fry wheat
10~15 parts of bud, 6~10 parts of Radix Glycyrrhizae, other auxiliary materials.
2. according to claim 1 for treating dermopathic external drug, which is characterized in that in parts by weight,
It is made of following raw materials:
12 parts of tribulus terrestris, 12 parts of Cortex Phellodendri, 12 parts of kuh-seng, 16 parts of purslane, 16 parts of Fructus Forsythiae, 16 parts of semen coicis is fried, 12 parts of Poria cocos, is fried
12 parts of Rhizoma Atractylodis Macrocephalae, 16 parts of oldenlandia diffusa, 12 parts of rhizoma alismatis, 12 parts of coloured malt, 8 parts of Radix Glycyrrhizae, other auxiliary materials.
3. according to claim 1 for treating dermopathic external drug, which is characterized in that other described auxiliary materials are solidifying
Jelly, wetting agent, pH adjusting agent.
4. according to claim 3 for treating dermopathic external drug, which is characterized in that the gelling agent is card wave
One or both of nurse and cellulose derivative.
5. according to claim 3 for treating dermopathic external drug, which is characterized in that the wetting agent is poly- mountain
One of pear ester class, phospholipid and poloxamer are a variety of.
6. according to claim 3 for treating dermopathic external drug, which is characterized in that the pH adjusting agent is three
Ethanol amine.
7. any preparation method for being used to treat dermopathic external drug, feature exist according to claim 1~6
In including the following steps:
S1. it is extracted after crushing tribulus terrestris, Fructus Forsythiae, oldenlandia diffusa with water, is filtered after extraction, supernatant is concentrated in vacuo
After obtain tribulus terrestris extraction, forsythia suspense extraction, herba hedyotis diffusae extract；
S2. ethyl alcohol is separately added into after crushing Cortex Phellodendri, kuh-seng, rhizoma alismatis and Radix Glycyrrhizae to extract, and is filtered after extraction, by filter vacuum
Phellodendron extract, shrubby sophora extract, Alisma extract and licorice are obtained after concentration；
S3. supercritical carbon dioxide extraction method is respectively adopted after crushing purslane, Poria cocos to extract, collects in separating still
Extract obtains purslane extract and tuckahoe extracts；
S4. semen coicis, coloured malt, rhizoma atractylodis macrocephalae will be fried to be extracted with water respectively, extracting solution is crossed into silicagel column respectively after extraction, is received
Collect efflux, obtains frying Semen Coicis extract, Fructus Hordei Germinatus (parched) extract and Rhizoma Atractylodis Macrocephalae (parched) extract after concentration；
S5. weigh by weight step S1~S4 preparation each medicinal substances extract, be dissolved in ethanol solution, sequentially add gelling agent,
Wetting agent adjusts pH=5~7 with pH adjusting agent, is uniformly mixed, can be obtained for treating dermopathic external drug.
8. according to claim 7 for treating the preparation method of dermopathic external drug, which is characterized in that described to add
The mass fraction for entering ethanol solution is 75%, and the additional amount of the ethanol solution is 100~200mL.
9. according to claim 7 for treating the preparation method of dermopathic external drug, which is characterized in that described solidifying
Jelly additional amount is 5~7g, and the wetting agent additional amount is 6~10g.
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