CN102949644A - Health-care product tablet for treating emphysema, relieving asthma and treating chronic bronchitis and preparation thereof - Google Patents

Abstract

The invention discloses a health-care product tablet for treating emphysema, relieving asthma and treating chronic bronchitis. The health-care product tablet comprises the following raw medicine ingredients by weight part: 30 parts of humulus scandens, 30 parts of codonopsis pilosula, 15 parts of tuckahoe, 5 parts of radix stemonae, 10 parts of radix asteris, 10 parts of semen raphani, 10 parts of semen brassicae and 30 parts of folium microcotis. The tablet related to the invention has the effects of reinforcing earth to generate metal, reducing Qi and expelling phlegm and is applied to the diseases such as the emphysema, the paracmasis of asthma and the chronic bronchitis. The traditional Chinese medicine combination of the health-care product tablet has the advantages of quick absorption, high biological availability, high effective blood concentration speed, independency, accurate quantification, stable quality, and the like. A conventional device can be used for finishing the production.

Description

Troche of health products and the preparation for the treatment of emphysema, Stable asthma, chronic bronchitis

Technical field

The invention belongs to field of health care products, relate to the troche of health products, particularly a kind of troche of health products and preparation that is used for the treatment of emphysema, Stable asthma, chronic bronchitis of a kind for the treatment of emphysema, Stable asthma, chronic bronchitis.

Background technology

Emphysema refer to the air flue elasticity attenuation of terminal bronchiole far-end (alveolar bronchiole, alveolar duct, alveolar sac and alveolar), the pathological state that excessive expansion, inflation and lung volume increase or destroy with airway walls simultaneously.By its pathogenic factor emphysema following several types is arranged: aging-lung emphysema, compensatory emphysema, interstitial emphysema, kitchen range emphysema, other intermittent emphysema, obstructive emphysema.

Chronic bronchitis (chronic bronchitis) is because infection or non-infective agent cause the chronic nonspecific inflammation of trachea, bronchial mucosa and surrounding tissue thereof.Its pathological characteristic is that bronchus body of gland hypertrophy, mucous secretion increase.Clinically have continuously more than 2 years, whenever continue the symptoms such as cough, expectoration or asthma more than three months.Early symptom is slight, and how in the winter time outbreak is alleviated after the spring is warm; Late period, inflammation increased the weight of, and symptom exists all the year round, regardless of season.Progression of disease again can concurrent obstructive emphysema, pulmonary heart disease, has a strong impact on work and healthy.

Primary disease is a common frdquently encountered disease, and according to the China whole nation seventies more than 6,000 ten thousand people's generaI investigation, prevalence is 3.82%.With age, prevalence increases progressively, and the prevalence more than 50 years old is up to 15% or more.Primary disease is popular to have substantial connection with smoking, area and environmental health etc.Smoker's prevalence is far above the non-smoker.The cold prevalence of boreal climate is higher than south.Industrial and mineral area atmospheric pollution is serious, and prevalence is higher than general city.The cause of disease is not yet fully clear, may be the long-term interactional result of many factors; Generally the cause of disease is divided into two aspects of exopathogenic factor and endogenous cause of ill.At present, the existing treatment emphysema in market, the catabasis of asthma, a lot of products of chronic bronchitis are cured the symptoms, not the disease, and it is long to reach the effective blood drug concentration time, easily forms dependency, and toxic and side effects is large, and dosage is large.And product of the present invention has overcome above shortcoming, have absorb fast, bioavailability is high, reach that effective blood drug concentration speed is fast, no dependence, quantitatively accurately, the advantage such as steady quality.

Summary of the invention

The purpose of this invention is to provide a kind of emphysema that are used for the treatment of, the catabasis of asthma, troche of health products of chronic bronchitis and preparation method thereof, it has building up the spleen to supplement the lung, and the effect of sending down the abnormal ascending QI expectorant is used for emphysema, the catabasis of asthma, the diseases such as chronic bronchitis.

Technical scheme of the present invention is: design a kind of emphysema that are used for the treatment of, the catabasis of asthma, the troche of health products of chronic bronchitis is characterized in that composition and weight proportion thereof that it contains crude drug are: 30 parts of Herba Ipomoeae Cairicaes, 30 parts of Radix Codonopsis, 15 parts in Poria, 5 parts of the Radixs Stemonae, 10 parts of Radix Asteriss, 10 parts of Semen Raphanis, 10 parts of Semen Sinapis Albaes, 30 parts of Folium Microcoris paniculataes.

Above-mentioned a kind of emphysema that are used for the treatment of, the catabasis of asthma, the preparation method of the troche of health products of chronic bronchitis, it may further comprise the steps:

1) by following weight ratio weighting raw materials: 30 parts of Herba Ipomoeae Cairicaes, 30 parts of Radix Codonopsis, 15 parts in Poria, 5 parts of the Radixs Stemonae, 10 parts of Radix Asteriss, 10 parts of Semen Raphanis, 10 parts of Semen Sinapis Albaes, 30 parts of Folium Microcoris paniculataes;

2) get above-mentioned eight flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, filtration is concentrated into relative density 1.10-1.20, temperature and is 80 ℃ thick paste, and spray drying is for subsequent use;

3) with step 2) with 32 parts of starch, 25 parts in dextrin, 5 parts of sucrose, mixing adds 85% ethanol.Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;

4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;

5) inner packing;

6) outer package, product inspection, warehouse-in.

Advantage of the present invention is: the Chinese medicinal tablet that contains among the present invention has building up the spleen to supplement the lung, and the effect of sending down the abnormal ascending QI expectorant is used for emphysema, the catabasis of asthma, the diseases such as chronic bronchitis.Monarch drug Herba Ipomoeae Cairicae heat-clearing and toxic substances removing in the prescription wherein, promoting blood circulation to remove blood stasis, diuresis.Be used for laryngopharynx swelling and pain, furuncle and phyma, carbuncle, furuncle, dysentery, hematuria, nebulousurine, traumatic injury, venom.Radix Codonopsis has invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.Be used for deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, the dyspnea due to deficiency cough, interior-heat is quenched one's thirst etc." Bencao Congxin " record: " invigorating the spleen and replenishing QI and taste, relieving thirst and restlessness.A little less than the middle feeble QI, mend in order to transfer, very smooth and proper.”。The Poria slightly sweet flavor is flat, enters the heart, lung, spleen channel.Has eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, the effect of mind tranquilizing and the heart calming.Radix Achyranthis Bidentatae cures mainly nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing.Be used for new chronic cough and cough pulmonary tuberculosis cough, pertussis; Outer head louse, body louse, enterobiasis, the pudendum Pruritus of being used for.Honey Radix Stemonae nourishing the lung to arrest cough.Be used for deficiency of YIN chronic cough.Radix Asteris nourishing the lung to keep the adverse QI downward, stopping coughing and removing phlegm.Be used for that abundant expectoration is breathed with cough, new chronic cough is coughed, the chronic cough hemoptysis.Semen Raphani enters spleen, stomach, lung meridian, can help digestion except swollen, and effect is remarkable, and the title of " rush wall fall wall " is arranged.Can be used for being used for the treatment of retention of food and drink, abdominal distention, constipation, stagnant dysentery, expectorant stops up and breathes with cough etc.Semen Sinapis Albae is used for cold-phlegm breathes with cough, distending pain in the chest and hypochondrium, the expectorant meridians that stagnate, joint numbness, pain, phlegm-damp oozing in the body, carbuncle of yin nature toxic swelling.The Folium Microcoris paniculatae heat clearing away disappears stagnant, and the dampness removing jaundice eliminating reduces phlegm.Be mainly used in flu, heatstroke, inappetence, dyspepsia, the abdominal pain of damp and hot dyspepsia, lack of appetite is had loose bowels, jaundice due to damp-heat.

Health product of the present invention have absorb fast, bioavailability is high, reach that effective blood drug concentration speed is fast, no dependence, quantitatively accurately, the advantage such as steady quality.

The specific embodiment

The invention will be further described below in conjunction with specific embodiment, but not as limitation of the present invention.The part that is not described in detail in the present embodiment is to adopt prior art, and industry standard or known approaches.

Embodiment 1

Described Chinese medicine preparation adopts following steps to make:

1) by following weight ratio weighting raw materials: 30 parts of Herba Ipomoeae Cairicaes, 30 parts of Radix Codonopsis, 15 parts in Poria, 5 parts of the Radixs Stemonae, 10 parts of Radix Asteriss, 10 parts of Semen Raphanis, 10 parts of Semen Sinapis Albaes, 30 parts of Folium Microcoris paniculataes;

2) get above-mentioned eight the flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, the filtration, be concentrated into relative density 1.10-1.20(80 ℃) thick paste, spray drying, for subsequent use;

3) with step 2) with 32 parts of starch, 25 parts in dextrin, 5 parts of sucrose, mixing adds 85% ethanol.Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;

4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;

5) inner packing;

6) outer package, product inspection, warehouse-in.

The below is this emphysema that are used for the treatment of of the present invention, the catabasis of asthma, and Chinese medicine composition tablet (hereinafter to be referred as embodiment 1) the treatment emphysema of the troche of health products preparation of chronic bronchitis, the catabasis of asthma, the clinical observation of chronic bronchitis:

1 data and method

1.1 physical data

Chronic bronchitis patient 200 examples that selection is received treatment voluntarily, male 103 examples, women 97 examples, 41-72 years old ages, average 48 years old, course of disease 2-18.The patient is prolonged and repeated cough, expectoration, asthma, infection all, show effect every year at least March, and continue more than 2 years or 2 years, and eliminating heart and lung diseases, be that its clinical symptoms, sign inspection all meet the chronic bronchitis diagnostic criteria, be not in the mood for, the complication such as liver, kidney, hemopoietic system, can be diagnosed as chronic bronchitis.Be divided at random treatment group 1, treatment group 2, treatment group 3, matched group, every group of 50 examples; Each is organized the patient age symptom and consists of without significant difference.Has comparability (P〉0.05).

1.2 Therapeutic Method

The treatment group Primary Care is consistent, and matched group is not taken medicine.The treatment group 1 usefulness embodiment of the invention 1, every day three times, one time 1,30 is a course for the treatment of.Treatment group 2 is used cefalexin, each 0.25g, every day 4 times; Treatment group 3 salbutamol sheet, each 2, every day 3 times.

2 results

2.1 curative effect determinate standard

Recovery from illness: symptom, sign inspection and x-ray rabat have all recovered normally, and the expectorant bacterium is cultivated negative; Produce effects: symptom, sign inspection recover normal, and the expectorant bacterium is cultivated and turns out cloudy x-ray rabat inflammatory lesion basic absorption; Progressive: sings and symptoms alleviates to some extent, and x-ray rabat inflammatory lesion partially absorbs; Invalid: the state of an illness is without obviously improving or increasing the weight of to some extent.

2.2 therapeutic outcome

?	Cure	Produce effects	Progressive	Invalid	Effective percentage
						Contrast	?	?	?	50	0
Treatment group 1	16	14	14	6	88%
						Treatment group 2	12	10	20	8	84%
Treatment group 3	10	7	24	9	82%

3 discuss

Chinese medicine is thought, it is relevant with important organ functional disorders such as liver, kidney, lung, spleens that chronic bronchitis merges emphysema. and the exopathogen such as wind and cold are to cause acute episode of chronic bronchitis or add one of key factor again, therefore the principle that Chinese traditional treatment should disease is mainly strengthening the body resistance, and strengthening spleen, tonifying kidney, to regulate the body deficiency and excess unbalance.Adopt Chinese medicine to import administration, the righting tonify deficiency, the cough-relieving that uncharms reaches the healing purpose.And then illustrate that embodiment 1 affiliated prescription is reliably effective in this invention.

Claims (2)

1. the troche of health products for the treatment of emphysema, Stable asthma, chronic bronchitis is characterized in that composition and weight proportion thereof that it contains crude drug are: 30 parts of Herba Ipomoeae Cairicaes, 30 parts of Radix Codonopsis, 15 parts in Poria, 5 parts of the Radixs Stemonae, 10 parts of Radix Asteriss, 10 parts of Semen Raphanis, 10 parts of Semen Sinapis Albaes, 30 parts of Folium Microcoris paniculataes.

2. treatment emphysema, the catabasis of asthma, the preparation method of the troche of health products of chronic bronchitis, it may further comprise the steps:

1) by following weight ratio weighting raw materials: 30 parts of Herba Ipomoeae Cairicaes, 30 parts of Radix Codonopsis, 15 parts in Poria, 5 parts of the Radixs Stemonae, 10 parts of Radix Asteriss, 10 parts of Semen Raphanis, 10 parts of Semen Sinapis Albaes, 30 parts of Folium Microcoris paniculataes;

2) get above-mentioned eight flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, filtration is concentrated into relative density 1.10-1.20, temperature and is 80 ℃ thick paste, and spray drying is for subsequent use;

3) with step 2) with 32 parts of starch, 25 parts in dextrin, 5 parts of sucrose, mixing adds 85% ethanol; Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;

4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;

5) inner packing;

6) outer package, product inspection, warehouse-in.