CN102949513A - Traditional Chinese medical health protection product for alleviating anxiety neurosis and preparation method thereof - Google Patents
Traditional Chinese medical health protection product for alleviating anxiety neurosis and preparation method thereof Download PDFInfo
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- CN102949513A CN102949513A CN 201210455193 CN201210455193A CN102949513A CN 102949513 A CN102949513 A CN 102949513A CN 201210455193 CN201210455193 CN 201210455193 CN 201210455193 A CN201210455193 A CN 201210455193A CN 102949513 A CN102949513 A CN 102949513A
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- anxiety neurosis
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Abstract
The invention discloses a traditional Chinese medical health protection product for alleviating anxiety neurosis and a preparation method thereof. The traditional Chinese medical health protection product comprises the following raw materials by weight: 10g of radix bupleuri, 6g of coptis chinensis, 10g of plumula nelumbinis, 20g of poria cocos, 10g of polygata tenuifolia, 10g of radix rehmanniae, 10g of cortex moutan radicis, 10g of radix paeoniae rubra, 10g of fried fructus aurantii, 30g of forged magnet, 30g of caulis polygoni multiflori, and 10g of radix paeoniae alba. The health protection product has the effects of clearing heat, relieving restlessness, and alleviating fluster and irritation, and is mainly applied for remedying anxiety neurosis. The traditional Chinese medical composition has the advantages of high biological availability, a fast speed of reaching effective blood concentration, non-dependency, accurate quantification, stable quality and the like, and the production can be finished via ordinary equipment.
Description
Technical field
The invention belongs to field of health care products, relate to a kind of Chinese medicine health care product of alleviating anxiety neurosis for the treatment of, particularly a kind of Chinese medicine health care product for alleviating anxiety neurosis and preparation method thereof.
Background technology
Anxiety is modal a kind of emotional state, such as having taken an examination soon, if you feel not review yourself, will nervously worry anxiety that Here it is.At this moment, usually can make the best use of time to review and take an examination, actively do the thing of energy anxiety reduction.This anxiety is a kind of protective response, is also referred to as the physiological anxiety.When the order of severity of anxiety and objective event or situation obviously are not inconsistent, when perhaps the persistent period is long, just become the pathologic anxiety, be called anxiety symptom, meet the dependent diagnostic standard, will be diagnosed as anxiety neurosis, be also referred to as anxiety disorder.Why can get anxiety neurosis? the cause of disease is still not clear at present.Studies show that anxiety neurosis and inherited genetic factors, characteristics of personality, adverse events, stressors, physical disease etc. all have relation, these factors can cause body nerve-endocrine system to get muddled, neurotransmitter is unbalance, thereby causes the appearance of the symptoms such as anxiety.Anxiety patient often has 5-HT (5-hydroxy tryptamine), NE(norepinephrine) etc. various neurotransmitters unbalance, and antianxiety drugs can make unbalance neurotransmitter trend normal, thereby anxiety symptom is disappeared, it is normal that emotion is recovered.At present, a lot of products of the existing treatment in market and pre-anxiety neurosis are cured the symptoms, not the disease, and it is long to reach the effective blood drug concentration time, and toxic and side effects is large, and dosage is large.And product of the present invention has overcome above shortcoming, have absorb fast, bioavailability is high, reach that effective blood drug concentration speed is fast, no dependence, quantitatively accurately, the advantage such as steady quality.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine health care product for alleviating anxiety neurosis and preparation method thereof, but its clearing heat and relieving fidgetness is alleviated nervous irritated.
Technical scheme of the present invention is: design a kind of Chinese medicine health care product for alleviating anxiety neurosis, it is characterized in that composition and weight proportion thereof that it contains crude drug are: Radix Bupleuri 10g, Rhizoma Coptidis 6g, Plumula Nelumbinis 10g, Poria 20g, Radix Polygalae 10g, Radix Rehmanniae 10g, Cortex Moutan 10g, Radix Paeoniae Rubra 10g, Fructus Aurantii (parched) 10g, Magnetitum (calcined) 30g, Caulis Polygoni Multiflori 30g, Radix Paeoniae Alba 10g.
Its preparation method of described a kind of Chinese medicine health care product for alleviating anxiety neurosis, it may further comprise the steps:
1) by following weight ratio weighting raw materials: Radix Bupleuri 10g, Rhizoma Coptidis 6g, Plumula Nelumbinis 10g, Poria 20g, Radix Polygalae 10g, Radix Rehmanniae 10g, Cortex Moutan 10g, Radix Paeoniae Rubra 10g, Fructus Aurantii (parched) 10g, Magnetitum (calcined) 30g, Caulis Polygoni Multiflori 30g, Radix Paeoniae Alba 10g;
2) get above-mentioned 12 flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, filtration is concentrated into relative density 1.10-1.20, temperature and is 80 ℃ thick paste, and spray drying is for subsequent use;
3) with step 2) and starch 32g, dextrin 25g, sucrose 5g, mixing adds 85% ethanol.Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;
4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;
5) inner packing;
6) outer package, product inspection, warehouse-in.
Advantage of the present invention is: the health product among the present invention have clearing heat and relieving fidgetness, alleviate nervous irritated effect.Wherein monarch drug Radix Bupleuri is clearind deficient heat Chinese medicine in the prescription, is used for cold, fever, alternate attack of chill and fever, malaria, stagnation of QI due to depression of the liver, sternal rib pain.The Rhizoma Coptidis heat clearing and damp drying, eliminating fire and detoxication.Be used for damp and hot feeling of fullness, the vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood is told nosebleed.Plumula Nelumbinis have clear away heart-fire reduce phlegm and internal heat, arresting seminal emission, the effect such as stop blooding, quench the thirst.Poria is used for the diseases such as irritability, cardiopalmus, insomnia.The Magnetitum (calcined) master is dizzy; The order flower; Deaf; Tinnitus; Palpitation with fear; Insomnia, the dyspnea of suffering from a deficiency of the kidney.Health product of the present invention have absorb fast, bioavailability is high, reach that effective blood drug concentration speed is fast, no dependence, quantitatively accurately, the advantage such as steady quality.
The specific embodiment
The invention will be further described below in conjunction with specific embodiment, but not as limitation of the present invention.The part that is not described in detail in the present embodiment is to adopt prior art, and industry standard or known approaches.
Embodiment 1
Described Chinese medicine preparation adopts following steps to make:
1) by following weight ratio weighting raw materials: Radix Bupleuri 10g, Rhizoma Coptidis 6g, Plumula Nelumbinis 10g, Poria 20g, Radix Polygalae 10g, Radix Rehmanniae 10g, Cortex Moutan 10g, Radix Paeoniae Rubra 10g, Fructus Aurantii (parched) 10g, Magnetitum (calcined) 30g, Caulis Polygoni Multiflori 30g, Radix Paeoniae Alba 10g;
2) get above-mentioned 12 the flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, the filtration, be concentrated into relative density 1.10-1.20(80 ℃) thick paste, spray drying, for subsequent use;
3) with step 2) and starch 32g, dextrin 25g, sucrose 5g, mixing adds 85% ethanol.Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;
4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;
5) inner packing;
6) outer package, product inspection, warehouse-in.
The below is the clinical observation of Chinese medicine composition tablet (hereinafter to be referred as embodiment 1) the treatment anxiety neurosis of this Chinese medicine health care product preparation for alleviating anxiety neurosis of the present invention:
1 data and method
1.1 physical data
Anxiety patient 120 examples of selecting outpatient service to receive treatment voluntarily, male's 60 examples, women's 60 examples,, age 18-65 year, male or female, the course of disease〉and 4 weeks, do not use antianxiety drugs or psychotropic drugs in 2 weeks.Be divided at random treatment group 1, treatment group 2, treatment group 3, and matched group, every group of 30 examples; Each is organized the patient age symptom and consists of without significant difference.Has comparability (P〉0.05).
1.2 Therapeutic Method
The treatment group Primary Care is consistent, and matched group is not taken medicine.The treatment group 1 usefulness embodiment of the invention 1, every day three times, one time 3,30d is a course for the treatment of.The each l sheet for the treatment of group 2 usefulness deanxit (Denmark spirit northern drugmaker), every day 2 times is oral; Treatment group 3 usefulness chlordiazepoxides (Yongning, Jinan pharmaceutical manufacturing), each 5mg, every day 3 times.
2 results
2.1 curative effect determinate standard
Clinical cure: clinical symptoms disappears substantially, and emotion is normal, does not affect working and learning, with examining 2 months without recurring: produce effects; Symptom and sign disappear substantially, only under a few cases mild are arranged, and do not affect work and life: take a turn for the better; Sx↓, sign improve, but recurrence is arranged, and be influential to people's work of living: invalid; Symptom and sign is without obviously improving or increasing the weight of.
2.2 therapeutic outcome
| Cure | Produce effects | Take a turn for the better | Invalid | Effective percentage | |
| Contrast | ? | ? | ? | 30 | 0 |
| Treatment group 1 | 15 | 8 | 4 | 3 | 90% |
| Treatment group 2 | 12 | 8 | 6 | 4 | 87% |
| Treatment group 3 | 10 | 6 | 9 | 5 | 83% |
3 discuss
The traditional Chinese medical science is thought, blood stored in the liver is regulated blood volume, is shaoyang within yin, and the property happiness reaches, and main catharsis is concerning the activity of whole body mechanism of qi.In addition, liver storing soul, and soul is relevant with the adjusting of spiritual emotion.As " the function threshold " of human body, liver has the every function effect of the body of mediation, makes it not too with too late.So it is dirty that treatment should be paid attention to kidney liver two, relieves inflammation or internal heat as fundamentum so that nourishing kidney is soothing the liver.Adopt pure Chinese medicine composition depressed liver-energy dispersing and QI regulating, warming kidney for dispelling cold, clearing away heat-fire reaches the healing purpose.And then illustrate that embodiment 1 affiliated prescription is reliably effective in this invention.
Claims (2)
1. Chinese medicine health care product of be used for alleviating anxiety neurosis is characterized in that composition and weight proportion thereof that it contains crude drug are: Radix Bupleuri 10g, Rhizoma Coptidis 6g, Plumula Nelumbinis 10g, Poria 20g, Radix Polygalae 10g, Radix Rehmanniae 10g, Cortex Moutan 10g, Radix Paeoniae Rubra 10g, Fructus Aurantii (parched) 10g, Magnetitum (calcined) 30g, Caulis Polygoni Multiflori 30g, Radix Paeoniae Alba 10g.
2. its preparation method of a kind of Chinese medicine health care product for alleviating anxiety neurosis according to claim 1, it may further comprise the steps:
1) by following weight ratio weighting raw materials: Radix Bupleuri 10g, Rhizoma Coptidis 6g, Plumula Nelumbinis 10g, Poria 20g, Radix Polygalae 10g, Radix Rehmanniae 10g, Cortex Moutan 10g, Radix Paeoniae Rubra 10g, Fructus Aurantii (parched) 10g, Magnetitum (calcined) 30g, Caulis Polygoni Multiflori 30g, Radix Paeoniae Alba 10g;
2) get above-mentioned 12 flavor medical materials, add 8 times of water gagings, decocts 3 times, each one hour, merging filtrate, filtration is concentrated into relative density 1.10-1.20, temperature and is 80 ℃ thick paste, and spray drying is for subsequent use;
3) with step 2) and starch 32g, dextrin 25g, sucrose 5g, mixing adds 85% ethanol; Soft material processed, 24 mesh sieves are granulated, and are 60 ℃ of forced air dryings, for subsequent use;
4) step 3) is added an amount of Pulvis Talci, Ying Zhi Suan Magnesium, mixing, tabletting, coating;
5) inner packing;
6) outer package, product inspection, warehouse-in.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201210455193 CN102949513A (en) | 2012-11-14 | 2012-11-14 | Traditional Chinese medical health protection product for alleviating anxiety neurosis and preparation method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 201210455193 CN102949513A (en) | 2012-11-14 | 2012-11-14 | Traditional Chinese medical health protection product for alleviating anxiety neurosis and preparation method thereof |
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| CN102949513A true CN102949513A (en) | 2013-03-06 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103861005A (en) * | 2014-03-26 | 2014-06-18 | 胡向仟 | Traditional Chinese medicine composition with anti-anxiety effect |
| CN106727982A (en) * | 2017-02-21 | 2017-05-31 | 上海世道健康科技有限公司 | It is a kind of to treat Chinese medicine composition of anxiety disorder and preparation method thereof |
-
2012
- 2012-11-14 CN CN 201210455193 patent/CN102949513A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103861005A (en) * | 2014-03-26 | 2014-06-18 | 胡向仟 | Traditional Chinese medicine composition with anti-anxiety effect |
| CN103861005B (en) * | 2014-03-26 | 2016-03-30 | 胡向仟 | A kind of Chinese medicine composition with angst resistance effect |
| CN106727982A (en) * | 2017-02-21 | 2017-05-31 | 上海世道健康科技有限公司 | It is a kind of to treat Chinese medicine composition of anxiety disorder and preparation method thereof |
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| PB01 | Publication | ||
| C04 | Withdrawal of patent application after publication (patent law 2001) | ||
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Application publication date: 20130306 |