CN102939006A - 杂环砜基代谢型谷氨酸受体第4亚型(mglur4)变构增效剂，组合物，以及用以治疗神经性障碍的方法 - Google Patents

杂环砜基代谢型谷氨酸受体第4亚型(mglur4)变构增效剂，组合物，以及用以治疗神经性障碍的方法 Download PDF

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CN102939006A
CN102939006A CN201180029055XA CN201180029055A CN102939006A CN 102939006 A CN102939006 A CN 102939006A CN 201180029055X A CN201180029055X A CN 201180029055XA CN 201180029055 A CN201180029055 A CN 201180029055A CN 102939006 A CN102939006 A CN 102939006A
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P·J·康那
C·W·林斯利
C·R·霍普金斯
C·D·韦乌尔
C·M·尼斯温德
R·D·高格廖蒂
张耀延
J·M·萨洛维奇
D·W·恩格尔斯
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Vanderbilt University
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201180029055XA 2010-05-12 2011-05-12 杂环砜基代谢型谷氨酸受体第4亚型(mglur4)变构增效剂，组合物，以及用以治疗神经性障碍的方法 Pending CN102939006A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33392610P 2010-05-12 2010-05-12
US61/333,926 2010-05-12
PCT/US2011/036308 WO2011143466A1 (en) 2010-05-12 2011-05-12 Heterocyclic sulfone mglur4 allosteric potentiators, compositions, and methods of treating neurological dysfunction

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CN102939006A true CN102939006A (zh) 2013-02-20

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US (1) US9192603B2 (https=)
EP (1) EP2568809A4 (https=)
JP (1) JP2013526544A (https=)
KR (1) KR20130079429A (https=)
CN (1) CN102939006A (https=)
AU (1) AU2011252974A1 (https=)
BR (1) BR112012028894A2 (https=)
CA (1) CA2798514A1 (https=)
IL (1) IL222854A0 (https=)
MX (1) MX2012013031A (https=)
RU (1) RU2012154447A (https=)
SG (1) SG185414A1 (https=)
WO (1) WO2011143466A1 (https=)

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