CN102908470A - Chinese materia medica preparation for tonifying Yang and preparation method thereof - Google Patents
Chinese materia medica preparation for tonifying Yang and preparation method thereof Download PDFInfo
- Publication number
- CN102908470A CN102908470A CN2012104532728A CN201210453272A CN102908470A CN 102908470 A CN102908470 A CN 102908470A CN 2012104532728 A CN2012104532728 A CN 2012104532728A CN 201210453272 A CN201210453272 A CN 201210453272A CN 102908470 A CN102908470 A CN 102908470A
- Authority
- CN
- China
- Prior art keywords
- radix
- gets
- ethanol
- liquid
- chinese medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 63
- 239000002398 materia medica Substances 0.000 title abstract description 8
- 239000003814 drug Substances 0.000 claims abstract description 93
- 235000008434 ginseng Nutrition 0.000 claims abstract description 31
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims abstract description 30
- 235000003140 Panax quinquefolius Nutrition 0.000 claims abstract description 30
- 241000005787 Cistanche Species 0.000 claims abstract description 27
- 239000002775 capsule Substances 0.000 claims abstract description 14
- 238000004519 manufacturing process Methods 0.000 claims abstract description 13
- 239000000463 material Substances 0.000 claims abstract description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 132
- 239000007788 liquid Substances 0.000 claims description 85
- 238000010438 heat treatment Methods 0.000 claims description 36
- 239000008280 blood Substances 0.000 claims description 33
- 210000004369 blood Anatomy 0.000 claims description 27
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 26
- 238000011282 treatment Methods 0.000 claims description 26
- 239000000706 filtrate Substances 0.000 claims description 24
- 235000014101 wine Nutrition 0.000 claims description 24
- 239000009636 Huang Qi Substances 0.000 claims description 23
- 238000002156 mixing Methods 0.000 claims description 22
- 239000000047 product Substances 0.000 claims description 18
- 239000008187 granular material Substances 0.000 claims description 17
- 239000000843 powder Substances 0.000 claims description 16
- 229940079593 drug Drugs 0.000 claims description 13
- 238000001816 cooling Methods 0.000 claims description 12
- 238000012856 packing Methods 0.000 claims description 12
- 238000001556 precipitation Methods 0.000 claims description 12
- 238000011084 recovery Methods 0.000 claims description 12
- 238000004064 recycling Methods 0.000 claims description 12
- 239000003643 water by type Substances 0.000 claims description 12
- 239000000284 extract Substances 0.000 claims description 11
- -1 spray drying Substances 0.000 claims description 10
- 239000012141 concentrate Substances 0.000 claims description 9
- 235000008504 concentrate Nutrition 0.000 claims description 9
- 239000013067 intermediate product Substances 0.000 claims description 9
- 239000003826 tablet Substances 0.000 claims description 9
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- 239000000203 mixture Substances 0.000 claims description 7
- 206010036596 premature ejaculation Diseases 0.000 claims description 7
- 239000006071 cream Substances 0.000 claims description 6
- 239000002552 dosage form Substances 0.000 claims description 6
- 239000002994 raw material Substances 0.000 claims description 6
- 238000001694 spray drying Methods 0.000 claims description 6
- 230000009471 action Effects 0.000 claims description 5
- 239000003098 androgen Substances 0.000 claims description 4
- 239000000919 ceramic Substances 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 4
- 230000037361 pathway Effects 0.000 claims description 4
- 230000002792 vascular Effects 0.000 claims description 4
- 206010024419 Libido decreased Diseases 0.000 claims description 3
- 230000001476 alcoholic effect Effects 0.000 claims description 3
- 239000005030 aluminium foil Substances 0.000 claims description 3
- 239000002245 particle Substances 0.000 claims description 3
- 230000001954 sterilising effect Effects 0.000 claims description 3
- 238000004659 sterilization and disinfection Methods 0.000 claims description 3
- 239000006188 syrup Substances 0.000 claims description 3
- 235000020357 syrup Nutrition 0.000 claims description 3
- 241000208340 Araliaceae Species 0.000 claims 6
- 241000668709 Dipterocarpus costatus Species 0.000 claims 5
- 210000003734 kidney Anatomy 0.000 abstract description 49
- 230000000694 effects Effects 0.000 abstract description 35
- 201000001881 impotence Diseases 0.000 abstract description 28
- 208000010228 Erectile Dysfunction Diseases 0.000 abstract description 25
- 230000001737 promoting effect Effects 0.000 abstract description 14
- 230000036299 sexual function Effects 0.000 abstract description 12
- 238000010792 warming Methods 0.000 abstract description 12
- 210000004204 blood vessel Anatomy 0.000 abstract description 6
- 240000004274 Sarcandra glabra Species 0.000 abstract description 3
- 230000036039 immunity Effects 0.000 abstract description 3
- 230000006872 improvement Effects 0.000 abstract description 3
- 241000123589 Dipsacus Species 0.000 abstract description 2
- 241001289529 Fallopia multiflora Species 0.000 abstract description 2
- 230000005284 excitation Effects 0.000 abstract description 2
- 241000382455 Angelica sinensis Species 0.000 abstract 1
- 241000045403 Astragalus propinquus Species 0.000 abstract 1
- 241000208689 Eucommia ulmoides Species 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 244000197580 Poria cocos Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 235000017276 Salvia Nutrition 0.000 abstract 1
- 240000007164 Salvia officinalis Species 0.000 abstract 1
- 235000006533 astragalus Nutrition 0.000 abstract 1
- 230000002567 autonomic effect Effects 0.000 abstract 1
- 229940100688 oral solution Drugs 0.000 abstract 1
- 240000004371 Panax ginseng Species 0.000 description 24
- 210000000988 bone and bone Anatomy 0.000 description 22
- 210000003205 muscle Anatomy 0.000 description 22
- 238000005728 strengthening Methods 0.000 description 21
- 210000004185 liver Anatomy 0.000 description 19
- 235000009508 confectionery Nutrition 0.000 description 15
- 208000002193 Pain Diseases 0.000 description 14
- 230000007812 deficiency Effects 0.000 description 14
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 14
- 201000010099 disease Diseases 0.000 description 12
- 230000017531 blood circulation Effects 0.000 description 11
- 230000006870 function Effects 0.000 description 11
- 210000000952 spleen Anatomy 0.000 description 11
- 210000003899 penis Anatomy 0.000 description 10
- 239000000243 solution Substances 0.000 description 10
- 208000006820 Arthralgia Diseases 0.000 description 9
- 239000000796 flavoring agent Substances 0.000 description 9
- 235000019634 flavors Nutrition 0.000 description 9
- 238000000034 method Methods 0.000 description 9
- 235000013339 cereals Nutrition 0.000 description 8
- 210000004209 hair Anatomy 0.000 description 8
- 230000001568 sexual effect Effects 0.000 description 8
- 206010027514 Metrorrhagia Diseases 0.000 description 7
- 230000008901 benefit Effects 0.000 description 7
- 238000013461 design Methods 0.000 description 7
- 231100000614 poison Toxicity 0.000 description 7
- 230000001105 regulatory effect Effects 0.000 description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 6
- 230000012010 growth Effects 0.000 description 6
- 239000006187 pill Substances 0.000 description 6
- 208000012201 sexual and gender identity disease Diseases 0.000 description 6
- 208000015891 sexual disease Diseases 0.000 description 6
- 210000001550 testis Anatomy 0.000 description 6
- 206010021118 Hypotonia Diseases 0.000 description 5
- 208000004880 Polyuria Diseases 0.000 description 5
- 208000033809 Suppuration Diseases 0.000 description 5
- 208000006673 asthma Diseases 0.000 description 5
- 230000035619 diuresis Effects 0.000 description 5
- 230000035622 drinking Effects 0.000 description 5
- 230000003203 everyday effect Effects 0.000 description 5
- 208000017561 flaccidity Diseases 0.000 description 5
- 210000000936 intestine Anatomy 0.000 description 5
- 210000000582 semen Anatomy 0.000 description 5
- 206010010774 Constipation Diseases 0.000 description 4
- 241000196324 Embryophyta Species 0.000 description 4
- 201000001880 Sexual dysfunction Diseases 0.000 description 4
- 208000031975 Yang Deficiency Diseases 0.000 description 4
- 206010016256 fatigue Diseases 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 210000004072 lung Anatomy 0.000 description 4
- 239000002574 poison Substances 0.000 description 4
- 230000003014 reinforcing effect Effects 0.000 description 4
- 231100000872 sexual dysfunction Toxicity 0.000 description 4
- 208000011580 syndromic disease Diseases 0.000 description 4
- 230000001225 therapeutic effect Effects 0.000 description 4
- 244000025254 Cannabis sativa Species 0.000 description 3
- 206010007247 Carbuncle Diseases 0.000 description 3
- 244000241463 Cullen corylifolium Species 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 206010020772 Hypertension Diseases 0.000 description 3
- 206010046543 Urinary incontinence Diseases 0.000 description 3
- 230000003712 anti-aging effect Effects 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 208000014674 injury Diseases 0.000 description 3
- 210000003127 knee Anatomy 0.000 description 3
- 210000002414 leg Anatomy 0.000 description 3
- 201000007227 lymph node tuberculosis Diseases 0.000 description 3
- 230000005906 menstruation Effects 0.000 description 3
- 230000007096 poisonous effect Effects 0.000 description 3
- 229930182490 saponin Natural products 0.000 description 3
- 235000017709 saponins Nutrition 0.000 description 3
- 201000000736 Amenorrhea Diseases 0.000 description 2
- 206010001928 Amenorrhoea Diseases 0.000 description 2
- 241000282465 Canis Species 0.000 description 2
- 244000293323 Cosmos caudatus Species 0.000 description 2
- 235000005956 Cosmos caudatus Nutrition 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 208000005171 Dysmenorrhea Diseases 0.000 description 2
- 206010013935 Dysmenorrhoea Diseases 0.000 description 2
- 241000628997 Flos Species 0.000 description 2
- 206010020880 Hypertrophy Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 206010057672 Male sexual dysfunction Diseases 0.000 description 2
- 208000019255 Menstrual disease Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 206010059013 Nocturnal emission Diseases 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 235000008331 Pinus X rigitaeda Nutrition 0.000 description 2
- 235000011613 Pinus brutia Nutrition 0.000 description 2
- 241000018646 Pinus brutia Species 0.000 description 2
- 208000001431 Psychomotor Agitation Diseases 0.000 description 2
- 206010038743 Restlessness Diseases 0.000 description 2
- 208000025747 Rheumatic disease Diseases 0.000 description 2
- 244000061456 Solanum tuberosum Species 0.000 description 2
- 235000002595 Solanum tuberosum Nutrition 0.000 description 2
- 208000005718 Stomach Neoplasms Diseases 0.000 description 2
- 208000009205 Tinnitus Diseases 0.000 description 2
- 208000027418 Wounds and injury Diseases 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 238000009825 accumulation Methods 0.000 description 2
- 231100000540 amenorrhea Toxicity 0.000 description 2
- 230000001093 anti-cancer Effects 0.000 description 2
- 230000002605 anti-dotal effect Effects 0.000 description 2
- 230000000259 anti-tumor effect Effects 0.000 description 2
- 206010003549 asthenia Diseases 0.000 description 2
- 210000000467 autonomic pathway Anatomy 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 229940126678 chinese medicines Drugs 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 230000000916 dilatatory effect Effects 0.000 description 2
- 230000001856 erectile effect Effects 0.000 description 2
- 210000003414 extremity Anatomy 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 206010017758 gastric cancer Diseases 0.000 description 2
- 229930182470 glycoside Natural products 0.000 description 2
- 238000005469 granulation Methods 0.000 description 2
- 230000003179 granulation Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 241000411851 herbal medicine Species 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 208000000509 infertility Diseases 0.000 description 2
- 230000036512 infertility Effects 0.000 description 2
- 208000021267 infertility disease Diseases 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 210000000629 knee joint Anatomy 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 230000007774 longterm Effects 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 230000002175 menstrual effect Effects 0.000 description 2
- 230000027939 micturition Effects 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 230000003119 painkilling effect Effects 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 210000003516 pericardium Anatomy 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 210000002826 placenta Anatomy 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- AQHHHDLHHXJYJD-UHFFFAOYSA-N propranolol Chemical compound C1=CC=C2C(OCC(O)CNC(C)C)=CC=CC2=C1 AQHHHDLHHXJYJD-UHFFFAOYSA-N 0.000 description 2
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 2
- 230000000552 rheumatic effect Effects 0.000 description 2
- 150000007949 saponins Chemical class 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 201000011549 stomach cancer Diseases 0.000 description 2
- 235000019640 taste Nutrition 0.000 description 2
- 231100000886 tinnitus Toxicity 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 230000017423 tissue regeneration Effects 0.000 description 2
- 230000008736 traumatic injury Effects 0.000 description 2
- 210000003462 vein Anatomy 0.000 description 2
- 239000000341 volatile oil Substances 0.000 description 2
- 238000003809 water extraction Methods 0.000 description 2
- GZCWLCBFPRFLKL-UHFFFAOYSA-N 1-prop-2-ynoxypropan-2-ol Chemical compound CC(O)COCC#C GZCWLCBFPRFLKL-UHFFFAOYSA-N 0.000 description 1
- MCSXGCZMEPXKIW-UHFFFAOYSA-N 3-hydroxy-4-[(4-methyl-2-nitrophenyl)diazenyl]-N-(3-nitrophenyl)naphthalene-2-carboxamide Chemical compound Cc1ccc(N=Nc2c(O)c(cc3ccccc23)C(=O)Nc2cccc(c2)[N+]([O-])=O)c(c1)[N+]([O-])=O MCSXGCZMEPXKIW-UHFFFAOYSA-N 0.000 description 1
- 241001538365 Accipiter nisus Species 0.000 description 1
- 102000013563 Acid Phosphatase Human genes 0.000 description 1
- 108010051457 Acid Phosphatase Proteins 0.000 description 1
- 229910000838 Al alloy Inorganic materials 0.000 description 1
- 241000213006 Angelica dahurica Species 0.000 description 1
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 240000002022 Anthriscus cerefolium Species 0.000 description 1
- 235000007258 Anthriscus cerefolium Nutrition 0.000 description 1
- 206010003011 Appendicitis Diseases 0.000 description 1
- 241000331777 Arisaema balansae Species 0.000 description 1
- 208000004429 Bacillary Dysentery Diseases 0.000 description 1
- 201000009030 Carcinoma Diseases 0.000 description 1
- 241001070941 Castanea Species 0.000 description 1
- 235000014036 Castanea Nutrition 0.000 description 1
- 206010007882 Cellulitis Diseases 0.000 description 1
- 208000017667 Chronic Disease Diseases 0.000 description 1
- 241000336291 Cistanche deserticola Species 0.000 description 1
- 241000756943 Codonopsis Species 0.000 description 1
- 206010010356 Congenital anomaly Diseases 0.000 description 1
- 244000084791 Curculigo orchioides Species 0.000 description 1
- 206010057315 Daydreaming Diseases 0.000 description 1
- 206010012455 Dermatitis exfoliative Diseases 0.000 description 1
- 241000123586 Dipsacaceae Species 0.000 description 1
- 108010001394 Disaccharidases Proteins 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000008967 Enuresis Diseases 0.000 description 1
- 241000208688 Eucommia Species 0.000 description 1
- 241000208686 Eucommiaceae Species 0.000 description 1
- 241000201295 Euphrasia Species 0.000 description 1
- 241000220485 Fabaceae Species 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 239000009083 Fructus psoraleae extract Substances 0.000 description 1
- 241001149422 Ganoderma applanatum Species 0.000 description 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 description 1
- VYAALAFRWREWLA-BVTMAQQCSA-N Geniposidic acid Natural products CCC1=CC[C@H]2[C@@H]1[C@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)OC=C2C(=O)O VYAALAFRWREWLA-BVTMAQQCSA-N 0.000 description 1
- ZJDOESGVOWAULF-UHFFFAOYSA-N Geniposidinsaeure Natural products OC1C(O)C(O)C(CO)OC1OC1C2C(CO)=CCC2C(C(O)=O)=CO1 ZJDOESGVOWAULF-UHFFFAOYSA-N 0.000 description 1
- 229920002683 Glycosaminoglycan Polymers 0.000 description 1
- 208000000616 Hemoptysis Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061245 Internal injury Diseases 0.000 description 1
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 1
- 241000207923 Lamiaceae Species 0.000 description 1
- 206010024238 Leptospirosis Diseases 0.000 description 1
- 208000028018 Lymphocytic leukaemia Diseases 0.000 description 1
- 244000131360 Morinda citrifolia Species 0.000 description 1
- 235000008898 Morinda citrifolia Nutrition 0.000 description 1
- 235000008248 Morinda citrifolia var citrifolia Nutrition 0.000 description 1
- 240000000249 Morus alba Species 0.000 description 1
- 235000008708 Morus alba Nutrition 0.000 description 1
- 101000804765 Mus musculus Lymphotactin Proteins 0.000 description 1
- 208000002454 Nasopharyngeal Carcinoma Diseases 0.000 description 1
- 206010061306 Nasopharyngeal cancer Diseases 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 241000123069 Ocyurus chrysurus Species 0.000 description 1
- 241000233855 Orchidaceae Species 0.000 description 1
- 235000002789 Panax ginseng Nutrition 0.000 description 1
- 244000046052 Phaseolus vulgaris Species 0.000 description 1
- 235000010627 Phaseolus vulgaris Nutrition 0.000 description 1
- 241000237636 Pheretima Species 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 241000219050 Polygonaceae Species 0.000 description 1
- 241000205407 Polygonum Species 0.000 description 1
- 201000004681 Psoriasis Diseases 0.000 description 1
- 235000010842 Sarcandra glabra Nutrition 0.000 description 1
- BZPMXJKRKXDRID-UOIKKKDVSA-N Scandoside Natural products OC[C@H]1O[C@@H](O[C@H]2CC=C([C@@H]3[C@@H](O)C=C(CO)[C@H]23)C(=O)O)[C@H](O)[C@@H](O)[C@@H]1O BZPMXJKRKXDRID-UOIKKKDVSA-N 0.000 description 1
- 241000576755 Sclerotia Species 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010041497 Spermatorrhoea Diseases 0.000 description 1
- 244000269722 Thea sinensis Species 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000012886 Vertigo Diseases 0.000 description 1
- 206010047642 Vitiligo Diseases 0.000 description 1
- 241001619444 Wolfiporia cocos Species 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000000118 anti-neoplastic effect Effects 0.000 description 1
- 239000002220 antihypertensive agent Substances 0.000 description 1
- 229940127088 antihypertensive drug Drugs 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000002026 chloroform extract Substances 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000004087 circulation Effects 0.000 description 1
- 230000009194 climbing Effects 0.000 description 1
- 230000015271 coagulation Effects 0.000 description 1
- 238000005345 coagulation Methods 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000002934 diuretic Substances 0.000 description 1
- 230000001882 diuretic effect Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 235000015177 dried meat Nutrition 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 238000002481 ethanol extraction Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000035558 fertility Effects 0.000 description 1
- 230000001605 fetal effect Effects 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000003517 fume Substances 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000004392 genitalia Anatomy 0.000 description 1
- 229930182494 ginsenoside Natural products 0.000 description 1
- 229940089161 ginsenoside Drugs 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 150000002338 glycosides Chemical class 0.000 description 1
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 235000021552 granulated sugar Nutrition 0.000 description 1
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 description 1
- 244000237330 gutta percha tree Species 0.000 description 1
- 230000037308 hair color Effects 0.000 description 1
- 230000003779 hair growth Effects 0.000 description 1
- 230000003760 hair shine Effects 0.000 description 1
- 235000013402 health food Nutrition 0.000 description 1
- 206010073071 hepatocellular carcinoma Diseases 0.000 description 1
- 206010019847 hepatosplenomegaly Diseases 0.000 description 1
- 210000001320 hippocampus Anatomy 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000001077 hypotensive effect Effects 0.000 description 1
- 239000003018 immunosuppressive agent Substances 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 231100000535 infertility Toxicity 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 235000021374 legumes Nutrition 0.000 description 1
- 208000032839 leukemia Diseases 0.000 description 1
- 201000005630 leukorrhea Diseases 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 208000003747 lymphoid leukemia Diseases 0.000 description 1
- 206010025482 malaise Diseases 0.000 description 1
- 239000012567 medical material Substances 0.000 description 1
- 206010027175 memory impairment Diseases 0.000 description 1
- 210000004914 menses Anatomy 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 230000036651 mood Effects 0.000 description 1
- 238000010137 moulding (plastic) Methods 0.000 description 1
- 201000011216 nasopharynx carcinoma Diseases 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 230000001379 nervous effect Effects 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 235000017524 noni Nutrition 0.000 description 1
- 231100000862 numbness Toxicity 0.000 description 1
- 230000027758 ovulation cycle Effects 0.000 description 1
- 230000003647 oxidation Effects 0.000 description 1
- 238000007254 oxidation reaction Methods 0.000 description 1
- 230000001734 parasympathetic effect Effects 0.000 description 1
- 230000032696 parturition Effects 0.000 description 1
- 210000005164 penile vein Anatomy 0.000 description 1
- RLLPVAHGXHCWKJ-UHFFFAOYSA-N permethrin Chemical compound CC1(C)C(C=C(Cl)Cl)C1C(=O)OCC1=CC=CC(OC=2C=CC=CC=2)=C1 RLLPVAHGXHCWKJ-UHFFFAOYSA-N 0.000 description 1
- 229930015704 phenylpropanoid Natural products 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000003389 potentiating effect Effects 0.000 description 1
- 238000003825 pressing Methods 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000007639 printing Methods 0.000 description 1
- 229960003712 propranolol Drugs 0.000 description 1
- 238000010298 pulverizing process Methods 0.000 description 1
- 230000001047 pyretic effect Effects 0.000 description 1
- 230000036647 reaction Effects 0.000 description 1
- 230000033458 reproduction Effects 0.000 description 1
- 210000004994 reproductive system Anatomy 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000002441 reversible effect Effects 0.000 description 1
- 230000033764 rhythmic process Effects 0.000 description 1
- 235000019991 rice wine Nutrition 0.000 description 1
- 239000012266 salt solution Substances 0.000 description 1
- 201000005113 shigellosis Diseases 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 208000019116 sleep disease Diseases 0.000 description 1
- 208000020685 sleep-wake disease Diseases 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 230000021595 spermatogenesis Effects 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 208000006379 syphilis Diseases 0.000 description 1
- KOWMJRJXZMEZLD-UHFFFAOYSA-N syringaresinol Chemical compound COC1=C(O)C(OC)=CC(C2C3C(C(OC3)C=3C=C(OC)C(O)=C(OC)C=3)CO2)=C1 KOWMJRJXZMEZLD-UHFFFAOYSA-N 0.000 description 1
- LVUPFEOCDSHRBL-UHFFFAOYSA-N syringaresinol Natural products COc1cccc(OC)c1C2OCC3C2COC3c4c(OC)cccc4OC LVUPFEOCDSHRBL-UHFFFAOYSA-N 0.000 description 1
- 230000009967 tasteless effect Effects 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 239000004577 thatch Substances 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 206010046901 vaginal discharge Diseases 0.000 description 1
- 231100000889 vertigo Toxicity 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a Chinese materia medica preparation for tonifying Yang. The Chinese materia medica preparation is characterized by being prepared by the following traditional Chinese medicine materials of glabrous sarcandra herb, radix morindae officinalis, teasel root, fructus psoraleae, astragalus mongholicus, polygonum multiflorum, angelica sinensis, eucommia ulmoides, rhizoma curculiginis, ginseng, poria cocos, the root of red-rooted salvia and cistanche to form an oral solution, a granula, a capsule, a tablet or medicinal liquor. The Chinese materia medica preparation is simple in formula, simple and convenient in production, convenient to take by patients and obvious in curative effect, has effects of expanding blood vessels, warming and invigorating kidney yang, dredging the channel and promoting autonomic nervous excitation, and has good effects on treating kidney lose and erectile dysfunction, building body, improving immunity of a human body and promoting sexual function improvement.
Description
Technical field
The present invention relates to a kind of health product, particularly Chinese medicine preparation of a kind of tonifying YANG take Chinese medicine as raw material and preparation method thereof.
Background technology
Man's erection disturbance (erectile dysfuction, ED) claim again sexual impotence.It is lower to have referred to that libido and sexual excitation stimulate, and penis anorthosis or erection are not hard, and can not keep erects has sexual intercourse.It is common clinically male sexual disorder, and sickness rate is about man crowd's 10%.
Erection is a kind of psychosomatic activity, is the synergistic synthesis result of several different systems (blood vessel, endocrine and nerve).Organic disease causes the diseases such as hyposexuality, seminal emission, premature ejaculation, sexual impotence, penis vessel leakage.
1, Chinese patent, application number: 02139615.9 applying date: 2002.09.13 title: a kind of the kidney invigorating Yang-invigorating pill for the treatment of sexual impotence and preparation method thereof application (patent right) people: Tan Cuiyu address: invention (design) people: the Tan Cuiyu of Hunan Province's Chaling County institute of traditional Chinese medicine; Tan Yang; Liu Chaoqun; The Liu Ruyi summary, a kind of medicine and preparation method for the treatment of sexual impotence, be characterized in being prepared into pill by Cornu Cervi Pantotrichum, Herba Epimedii, Herba Cistanches, Radix Ginseng, Fructus Corni, Pheretima medicine and Chinese medicine runny plaste (dry levigation), its Chinese medicine runny plaste is to adopt nine kinds to have that kidney-nourishing and anti-senile is old, the QI invigorating that nourishes blood, and the medical material of the functions such as bitterness consolidating YIN and promoting diuresis with drugs of tasteless flavour boils concentrated forming.This kidney invigorating Yang-invigorating pill, giving consideration to both the incidental and fundamental, it is rapid, evident in efficacy to have a pharmacological reaction, not only can tonifying YANG play flaccidity, and have soothing liver-QI strong muscle, brain-tonifying and kidney-nourishing and anti-aging effects.
2, Chinese patent, application number: 03108058.8 applying date: 2003.05.21 title: a kind of Chinese medicine with tonifying YANG kidney benefiting functions and preparation method thereof application (patent right) people: Beilin Pharmaceutical Co., Ltd., Xi'an address: No. 75 inventions of Dongguan, Xian City, Shanxi Province Long Qu fort (design) people: Huang Xiaohua; Fu Bin; The Zhao Tong summary, a kind of Chinese medicine with tonifying YANG kidney benefiting functions and preparation method thereof.Motherland's medical science is thought " the kidney being the origin of congenital constitution, and taste are the foundation of acquired constitution ", and kidney and partes corporis humani have close contact, and the vital essence prosperity and decline of kidney is directly connected to the healthy and old and feeble of reproduction, growth, growth and human body.Herba Epimedii in this prescription, kidney invigorating and YANG supporting is the wet medicine of mending the gate of vitality, and the merit of yang-strengthening qi-benefiting and physique-strengthening is arranged; Testis et Pentis Canis, Hippocampus warming and recuperating the kidney-YANG play kidney invigorating and YANG supporting altogether, and controlling nocturnal emission with astringent drugs is given birth to the effect of marrow.It has the tonifying YANG kidney tonifying, and strongly invigorating QI and blood adds the smart marrow of giving birth to, and keeps fit the function of brain-strengthening, is used for the treatment of geromorphism, sexual hypofunction, waist and leg ache, fatigue and weak, insomnia forgetfulness, the Chinese medicine of the diseases such as absentminded.
3, Chinese patent, application number: the 93111165.X applying date: 1993.05.25 title: Antisenile health-care medicine and production method application (patent right) people: Zhang Yanxing address: the Shenyang City, Liaoning Province Shenhe District is No. 1 invention in Building 4, Unit 4, No. 3 building, residential quarter (design) people: Zhang Yanxing summary in Yian city, street, a kind of Antisenile health-care medicine and production method, prescription adopts Margarita and Radix Ginseng, Placenta Hominis, the group such as Herba Epimedii medicine, elder generation's bionic extraction pearl essence, again group's medicine is carried out water extraction, be mixed with the modulation of Margarita finishing water and with group's medicament extracting solution.Its advantage is: without animal genital and western medicine composition, the natural Chinese medicines material is made, human body is had no side effect, and the treatability hormone sexual disorder that goes down and cause not only, and other disease that can cause sexual dysfunction played the subsidy therapeutical effect.Thereby men and women, old and young all can take, and YIN nourishing and YANG strengthening fills blood, and adds marrow, and the peace internal organs are anti-ageing anticancer, building body, and it is remarkable to strengthen men and women's sexual function effect, is the desirable health care medicine of middle-aged and elderly people.
4, Chinese patent, application number: 93101612.6 applyings date: 1993.02.18 title: the Chinese prescription of yang invigorating functions, preparation and preparation technology's application (patent right) people thereof: Huanan Pharmaceutics Factory, Shilong Town, Guangdong Prov. address: Shilong Town, Dongguan City, Guangdong Province No. 18 inventions in industry main road (design) people: Yuan Ruiguang summary, a kind of Chinese prescription with yang invigorating functions, preparation " strong that sun " and preparation method thereof, prescription is combined by ten Chinese medicine of the five flavours, can be processed into oral liquid, capsule, tablet, electuary, pill, fluid extract and other peroral dosage form.Through water or ethanol extraction, or be ground into powder and further be processed into preparation.This prescription is a kind of safely and effectively Chinese prescription that improves and treat male sexual disorder.
5, Chinese patent, application number: 91110960.9 applyings date: 1991.11.29 title: a kind of manufacture method application (patent right) people of warming the kidney to invigorate YANG Chinese patent medicine: Liaoning Huanren Chinese Pharmaceutical Factory, address: Chaoyang street, Huan Renxian Huan Ren town, Liaoning Province invention (design) people: Zhao Shuqin; Wang Shijie; Wang Zhongren, summary, a kind of manufacture method of medical drugs is particularly about a kind of manufacture method of warming the kidney to invigorate YANG Chinese patent medicine.The method is made take 12 flavors such as Chinese medicine Cornu Cervi Degelatinatum, Bombycis mori, Herba Epimedii, Semen Cuscutae, Herba Pyrolae, Semen Allii Tuberosi, Herba Ephedrae, Poria, Radix Glycyrrhizae, Radix Rehmanniae Preparata, Testis et Pentis Canis, Testis Et penis Equi as Raw material processing, manufacturing process is simple, product price is cheap, drug effect is remarkable, non-stimulated to human body, have no side effect, be the treatment because of comparatively desirable Chinese patent medicines of the diseases such as sexual hypofunction such as the caused sexual impotence of suffering from a deficiency of the kidney.
6, Chinese patent, application number: 00123469.2 applying date: 2000.08.18 title: a kind of Chinese medicine preparation for the treatment of male sexual dysfunction and preparation method thereof application (patent right) people: Jiao is location, Haiti more: Xi Hu village, Shahe City, Hebei province invention (design) people: Jiao Genghai has made a summary this disclosure of the Invention a kind of Chinese medicine preparation for the treatment of male sexual dysfunction, it is with Radix Ginseng, Fructus Lycii, Radix Angelicae Sinensis, Rhizoma Dioscoreae, Cornu Cervi Pantotrichum, Placenta Hominis, the 25 flavor Chinese medicines such as Testudinis Cornu Cervi are raw material, different qualities according to every flavor Chinese medicine, formulated pill after the pretreatment differently respectively, the party's prescription is rigorous, compatibility is reasonable, can reach promoting blood circulation to remove obstruction in the collateral, nourishing the liver and kidney, the nourishing YIN tonifying YANG, strong waist knee joint, resisting fatigue, the effect of clear knowledge.Be used for the treatment of disease and the instant effects such as sexual impotence, premature ejaculation, sexual disorder and lassitude, sore waist and aching in the waist and the back, cure rate is high, safe without toxic side effect, and manufacture method is unique, easy.
7, Chinese patent, application number: 99101130.9 applyings date: 1999.01.08 title: application at Chinese medicine Yujingling of the treatment of sexual dysfunction disease and preparation method thereof (patent right) people: Huanghai Sea howl address: county town, Yihuang, Jiangxi Province is to invention (design) people of No. 2 Yihuang County, river road out-patient department of institute of traditional Chinese medicine: the Huanghai Sea is maked a whistling sound and is made a summary, Chinese medicine Yujingling of a kind of the treatment of sexual dysfunction disease and preparation method thereof, this Yujingling is by the Chinese crude drug Herba Epimedii, fly Bombycis mori, Semen Cuscutae, Herba Cistanches, Actinolitum, Ootheca Mantidis, Radix Achyranthis Bidentatae, Fructus Rubi, Testis et penis callorhini, large Fructus Jujubae forms, the mixing after pulverizing respectively of above-mentioned Chinese crude drug namely gets the powder-type medicine, it can make tablet by traditional pharmaceutical technology as required, pill, the medicine of the dosage forms such as capsule also can be used as the allotment of health food.Go macroscopic view for reproductive system illness pathogeny this Yujingling centered by the rehabilitation sexual dysfunction, protect liquid as the basis take spermatogenesis, plays flaccidity as main body take tonifying YANG, to activate libido as prerequisite, finally reaches the purpose of fertility.Clinical use, cure rate are 91.2%, and effective percentage is 5.4%, and inefficiency is 3.4%, and total effective rate is 96.6%.
From above-mentioned document, it is each has something to recommend him to see from clinical effectiveness.But the treatment that present bright stem blood vessel leakage causes obstacle does not also have better way at present except performing the operation.Research and develop a kind of penis vessel is leaked therapeutical effect and the excited parasympathetic nervous effect of energy are arranged, promote sexual function to recover and have the effect of blood vessel dilating, warming and recuperating the kidney-YANG, dredging the meridian, the excitement of promotion autonomic nerve, to treatment deficiency of the kidney, sexual impotence, improve the body and culature and improve body immunity, promote the Chinese medicine preparation of improvement of sexual function effect to be necessary.
Summary of the invention
The object of the present invention is to provide a kind of prescription simple, produce easy, patient's taking convenience, evident in efficacy, effect with blood vessel dilating, warming and recuperating the kidney-YANG, dredging the meridian, the excitement of promotion autonomic nerve is to treatment deficiency of the kidney, sexual impotence, the Chinese medicine preparation and preparation method thereof that improves the body and culature and improve body immunity, promote a kind of tonifying YANG of improvement of sexual function.
The present invention is achieved in that
The Chinese medicine preparation of tonifying YANG of the present invention is to be made by the raw material of Chinese medicine of following parts by weight:
Herba Pileae Scriptae 10-30;
Bar halberd 10-30;
Radix Dipsaci 10-30;
Fructus Psoraleae 10-30;
Radix Astragali 10-30;
Radix Polygoni Multiflori 10-30;
Radix Angelicae Sinensis 5-10;
Cortex Eucommiae 10-30;
Rhizoma Curculiginis 10-30;
Radix Ginseng 5-20;
Poria 10-30;
Radix Salviae Miltiorrhizae 10-30;
Herba Cistanches 10-30.
The present invention is by Herba Pileae Scriptae, the bar halberd, Radix Dipsaci, Fructus Psoraleae, the Radix Astragali, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Cortex Eucommiae, Rhizoma Curculiginis, Radix Ginseng, Poria, Radix Salviae Miltiorrhizae and Herba Cistanches form, have strong vim and vigour, bone and muscle strengthening, method rheumatism, kidney-yang nourishing, invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, continuous folding is hindered, end metrorrhagia, helping inspiration to relieve asthma, warming spleen and stopping diarrha, benefiting essence-blood, bone and muscle strengthening, blood fat reducing, defying age, enrich blood, invigorate blood circulation, regulating menstruation, pain relieving, intestine moistening, invigorating QI to consolidate the body surface resistance, the diuresis poison holding, evacuation of pus, the effect of expelling pus and promoting granulation, control the sexual impotence cold sperm; urinary incontinence; metrorrhagia; trusted subordinate's cold type of pain; cold arthralgia of loins and legs; carbuncle; scrofula; the effect of yang deficiency cold diarrhea, thereby reach the purpose of tonifying YANG.
Each medicine active ingredient of the Chinese medicine preparation Chinese medicine formula of above-described tonifying YANG is analyzed:
Herba Pileae Scriptae: [another name] Herba Pileae Scriptae, Herba Pileae Scriptae, synthetism lotus, Herba Sarcandrae, synthetism is blue.[Latin]
Herba SarcandraeHerba Pileae Scriptae (English) Glabrous Sarcandra Herb is the Herb of gold chestnut orchid Herba Pileae Scriptae Sarcandra glabra (Thunb.) Nakai.Be born in gully, the dark and damp ground of trench woods, be distributed in East China, Central-South, southwestern.Summer, autumn excavate, and remove impurity, dry.Slightly warm in nature, bitter in the mouth, suffering.Anti-inflammation, dispelling wind and removing obstruction in the collateral, blood circulation promoting and dispersing pathogen accumulation.Be used for pneumonia, appendicitis, cellulitis, rheumatic arthralgia, traumatic injury, tumor.
Bar halberd: [another name] Radix Morindae Officinalis, bar halberd, Ba Jitian, halberd sky, Radix Morindae Officinalis, cat intestinal muscle, rabbit intestinal; [English] Medicinal Indianmulberry Root [Latin]
Radix Morindae OfficinalisBar halberd genus rubia section climbing plant, Radix Morindae Officinalis acrid in the mouth, sweet, slightly warm in nature; Return liver, kidney channel; The body profit is mended and double faling apart; Special effect with strong vim and vigour, bone and muscle strengthening, method rheumatism, kidney-yang nourishing.Cure mainly (effect): impotence due to deficiency of the kidney; The seminal emission premature ejaculation; Few abdomen cold type of pain; Incontinence of urine; Cold womb is infertile; Anemofrigid-damp arthralgia; Soreness of the waist and knees; Rheumatism limb gas.1. kidney yang deficiency, the sexual impotence erectile problem, the emission and spermatorrhea person, can with the compatibilities such as Herba Cistanches, Radix Aconiti Lateralis Preparata, Fructus Psoraleae, with the reinforcing the kindey to control nocturnal emission tonifying YANG.2. deficiency of the liver and kindey, the soft person of muscles and bones flaccidity, can with the compatibilities such as Herba Cistanches, the Cortex Eucommiae, Semen Cuscutae, grass solution, with warming the liver kidney, strengthening bone and muscle.
Radix Dipsaci: [another name] Radix Dipsaci, imperial bean, genus folding, synthetism, south grass, Rhizoma seu Herba Elatostematis stewardii, drum hammer grass, shaven head, river Radix Raphani root, horse Ji, black crow head, little Radix Dipsaci, chervil.The root of Dipsacaceae herbaceos perennial Radix Dipsaci is because energy " synthetism of continuous folding " is gained the name.For.English name: Himalayan Teasel Root, Latin medicine name:
Radix Dipsaci Asperoidis[meridian distribution of property and flavor] bitter in the mouth; Hot; Slightly warm in nature.Return liver; Kidney channel.[effect] invigorating the liver and kidney; Bone and muscle strengthening; Blood circulation regulating; Continuous folding is hindered; End metrorrhagia.Be used for aching pain in waist and back; The podomere flaccidity syndrome and arthralgia syndrome; Fall pounce on wound, decrease muscle folding bone, red, metrorrhagia is leaked in fetal movement, seminal emission, leukorrhagia, carbuncle skin ulcer are swollen.Prepared RADIX DIPSACI with yellow rice wine is multiplex in rheumatic arthralgia, injury from falling down.Prepared RADIX DIPSACI with salt solution is multiplex in soreness of the waist and knees." the southern regions of the Yunnan Province book on Chinese herbal medicine ": " meridians decide in tonifying liver, bone and muscle strengthening, end in the warp (muscles and bones) and ache, and are antiabortive, control the married woman leucorrhea, tissue regeneration promoting blood, and removing blood stasis with potent drugs blood, the stillborn fetus that falls, the cough-relieving hemoptysis of coughing is controlled red white turbid urine.”
Fructus Psoraleae: [another name] be the son of Semen Allii Tuberosi, the solid fat of mother-in-law, Fructus Psoraleae, benefit bone sparrow hawk, FRUCTUS PSORALEAE, Hu Fructus Psoraleae, Ji Guzi, FRUCTUS PSORALEAE bone fat, Fructus Psoraleae, event fat, event recklessly, is the fruit of legumes psoraleae.[Chinese phonetic alphabet]: bu gu zhi [English name]: Malaytea Scurfpea Fruit, Fruit of Malaytea Scurfpea[latin name]
Psoralea corylifolia L. [meridian distribution of property and flavor] acrid in the mouth; Bitter; Fructus Psoraleae warm in nature (5) kidney; Pericardium; Spleen; Stomach; Lung meridian [effect] reinforcing the kidney and supporting YANG; Helping inspiration to relieve asthma; Warming spleen and stopping diarrha.Main insufficiency of kidney-YANG; Below element deficiency and cold; Chills and pain of the waist and kness; Impotence and seminal emission; Frequent micturition; The enuresis; Failure of the kidney in receiving QI; Dyspnea due to deficiency is more than; Asthenia of both the spleen and kidney; The stool chronic diarrhea; The outer vitiligo that is used for; Speckle is bald; Psoriasis.
The Radix Astragali: [another name] Radix Astragali, Radix Astragali, only mulberry, another name for Sichuan Province fat, hundred, hundred medicines, [latin name] Leguminosae invigorating QI to consolidate the body surface resistance, diuresis poison holding, QI invigorating invigorating middle warmer.The Radix Astragali is leguminous plant, and it is the Chinese medicine of commonly using simply.Its main pharmacological is " benefiting QI for strengthening the superficies ", can " diuretic ", and also can " promoting pus discharge and tissue regeneration strengthening ".Has invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, the effect of expelling pus and promoting granulation.
Radix Polygoni Multiflori: [another name] Radix Polygoni Multiflori, CHISHOU crow, ferrum sliding weight of steelyard, red interior slake Caulis Polygoni Multiflori, Latin name: Polygonum multiflorum Thunb.[English name] RADIX POLYGONI MULTIFLORI, section's name: Polygonaceae Polygonaceae, Polygonum, perennial herb is without hair.Radix Polygoni Multiflori Preparata is present unique traditional key medicine with anti-aging effects that is proved to be, and property is bitter, sweet, puckery, warm, returns liver, the heart, kidney channel to have invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening, blood fat reducing, antidotal effect.Be used for blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, weakness due to chronic disease, hyperlipidemia.
Radix Angelicae Sinensis: the English Chinese Angelica of phonetic Danggui Latin
Radix Angelicae SinensisPerennial herb, Herb have special fragrance; The dried Shennong's Herbal of returning of different name, horse hair Radix Angelicae Sinensis Collective Notes to the Canon of Materia medica, Radix Angelicae Sinensis, horse hair are returned Compendium of Material Medica, and cloud is returned (Yunnan), western Radix Angelicae Sinensis, Min Radix Angelicae Sinensis (Gan Shi).Radix Angelicae Sinensis is sweet, hot, temperature.Return liver, the heart, spleen channel, effect is enriched blood, and invigorates blood circulation regulating menstruation, pain relieving, intestine moistening.Be used for heart-liver blood deficiency, shallow complexion, dizzy cardiopalmus etc.; Be used for blood deficiency or blood deficiency and have the menoxenia that the stasis of blood stagnates, dysmenorrhea, the diseases such as amenorrhea concurrently; Be used for blood deficiency, stasis and have cold coagulation concurrently, and traumatic injury, the pain card of wind-damp numbness; Be used for ulcer sores; Be used for the constipation of blood deficiency dryness of the intestine.
The Cortex Eucommiae: be the dry bark of the Eucommiaceae plant Cortex Eucommiae (Eucommia ulmoides Oliver), [nature and flavor] Gan Weixin, temperature.1. " herbal classic ": " acrid in the mouth is flat." 2. " not Lu ": " be sweet, and temperature is nontoxic." 3. " property of medicine opinion ": " bitter in the mouth." 4. hot, flat, nontoxic, regulate the flow of vital energy and enrich blood.5. Pharmacopoeia of the People's Republic of China version in 2010 is one one: " sweet, temperature.Return liver, kidney channel." extract and the decoct of eucommia bark have lasting hypotensive effect to animal.Modern pharmacology experimental results show that the Cortex Eucommiae has anticancer effect with pressing down cancer, and its effective ingredient is relevant with its contained lignanoid, Phenylpropanoid Glycosides and iridoid.According to report, the contained Geniposidic acid methyl ester of the Cortex Eucommiae has antineoplastic action.The contained syringaresinol disaccharidase glycosides of the Cortex Eucommiae has active preferably in Lymphocytic leukemia P388 (Ps) system, and concentration 12.5 mg/kg can control the T/C value) 〉=126.Isolated the general flavone from the Folium Eucommiae chloroform extract such as Okada is a kind of immunosuppressive substance of the T of interference lymphocyte function, and human nasopharyngeal carcinoma (KB) and mouse lymphotactin leukemia (P388) are all had growth inhibitory activity.
Rhizoma Curculiginis (Curculigo orchioides Gaertn.), begin to be stated from " Haiyao Bencao, Oversea Materia Medica ", its leaf is like thatch, and root stock takes the smart marrow of mending of benefit for a long time, increases spirit, so the title of Rhizoma Curculiginis is arranged, [another name] brown (Sichuan, Guizhou), Rhizoma Curculiginis (Sichuan), mountain Radix Codonopsis (Fujian), Radix Scorzonerae Albicaulis (Yunnan), Radix Glehniae (Hainan).The rhizome of amrallid Rhizoma Curculiginis is the Chinese medicine Rhizoma Curculiginis that Pharmacopoeia of the People's Republic of China version First in 2005 records, [meridian distribution of property and flavor] suffering, and temperature, poisonous.1. " Haiyao Bencao, Oversea Materia Medica ": sweet in the mouth, little preventing, slightly poisonous.2. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": warm in nature, acrid in the mouth is little salty.3. " detailed outline): hot in nature.Enter kidney, Liver Channel.[effect] the kidney warming sun, strengthening bone and muscle.Control the sexual impotence cold sperm, urinary incontinence, metrorrhagia, trusted subordinate's cold type of pain, cold arthralgia of loins and legs, carbuncle, scrofula, yang deficiency cold diarrhea.Sexual impotence is smart cold, and the waist knee joint is air-cooled, the diseases such as muscles and bones flaccidity syndrome and arthralgia syndrome.The Rhizoma Curculiginis ball is arranged in the ancient prescription, can strengthening bone and muscle, benefit spirit, make eye bright, black beard and hair." the SHENGCAO property of medicine is standby to be wanted ": the kidney invigorating, nebulousurine is controlled in pain relieving, the reason phlegm-fire, pot is carnivorous.Ten steam nine shines, and hides with granulated sugar, and morning, tea sent, and can strengthen spirit, black beard and hair.Have the effect of reinforcing the kidney and supporting YANG, benefiting essence-blood, bone and muscle strengthening and promoting the circulation of blood detumescence, be mainly used in the diseases such as insufficiency of kidney-YANG, impotence and seminal emission, chronic consumptive disease internal injury and bones and muscles pain.
Radix Ginseng: Latin plant name:
Panax ginseng C. A. Mey, sweet, the little hardship of property, tepor, strongly invigorating primordial QI, invigorating the spleen to benefit the lung; According to the literature, the multiple Saponin, ginseng polysaccharide and the ginseng essential oil that contain in the Radix Ginseng have antitumor action.The ginsenoside can make cancerous cell break up, induce and reverse and be non-cancerous cell.Stem and leaf of Radix Ginseng total saponins can suppress the speed of growth and the splitting ability of Human Gastric Cancer Cells In Vitro, increases the former content of endocellular sugar, reduces mucopolysaccharide and activity of acid phosphatase in the cell, plays certain obstruction Growth of Gastric and the effect of propagation.Flos Ginseng, leaf glycol group Saponin also have certain antitumor action external.Radix Ginseng aerial parts volatile oil composition can make the gastric cancer of In vitro culture and hepatoma carcinoma cell number reduce, growth is suppressed, dead cancerous cell number increases.
Poria: [another name] beautiful spirit, Poria, Wan Linggui, Fu Tu, Fu Tu (" herbal classic "), Poria (" Records of the Historian "), Fu Ling (" extensively refined "), Fu Ling, volt Tu (Tang Materia Medica), pine fat (" account pearl "), lie prostrate tire (" Youyangzazu ") deep red morning, Poria (" Yunnan Hai Yu weigh will "), Fu rabbit (" detailed outline "), pine potato, Masson Pine potato, Song Ling (" Guangxi Chinese medicinal herbal ").Be the dry sclerotia of intending shelf fungus section fungus Poria, often colonize on the pinaster root, shape such as Rhizoma Dioscoreae esculentae, spherical, crust light brown or pitchy, inner pink colour or white are called Poria or Poria after making with extra care.[Latin formal name used at school] Wolfiporia cocos[nature,taste and action] Rhizoma Smilacis Glabrae sweet in the mouth, light, property is flat.Heat clearing away is arranged, dehumidifying, detoxifcation, the function in sharp joint.[curing mainly usage] is used for joint aches, urinary tract infection, and leucorrhea, damp and hot sore, syphilis, erythroderma, acute bacillary dysentery, scrofula, and be used for the treatment of leptospirosis.
Radix Salviae Miltiorrhizae: [another name] blood is taken root, Radix Salviae Miltiorrhizae, Herba Wedeliae Wallichii, Arisaema balansae Engl. [English name] Dan one ShenRoot[Latin]
Radix Salviae Miltiorrhizae, be the dicotyledon Labiatae, dry root and rhizome, function cures mainly: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire.Be used for that menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection are swollen and ache, hepatosplenomegaly, angina pectoris.
Herba Cistanches: [Latin]
Cistanche deserticola Ma[another name] golden Radix Crotalariae szemoensis, rue greatly, dried meat floss Rong, black commandant, vertical Rong, horse foot, Ma Zhi, Herba Cistanches, very little ruing, Herba Cistanches sweet in the mouth, salty, warm in nature, return kidney, large intestine channel, matter profit meat is thick, calmly with fall; Has kidney-replenishing, benefiting essence-blood, the effect of loosening bowel to relieve constipation; Cure mainly kidney yang deficiency, essence and blood loss, sexual impotence, seminal emission, chills and pain of the waist and kness, tinnitus order flower, foul leukorrhea, frequent micturition, delay of menstrual cycle, metrorrhagia, sterility and infertility, dryness of the intestine constipation.
By the conventional formulation technique of relevant dosage form, add appropriate amount of auxiliary materials and make corresponding dosage form, but above-mentioned Chinese medicine preparation can also be made the dosage form of oral liquid, granule, capsule, tablet or other pharmacy.
The Chinese medicine preparation of above-described tonifying YANG also can be made medicated wine.
The Chinese medicine preparation of above-described tonifying YANG is tentatively on probation in the project of clinical hair growth promoting hair color, and reflection is good, without obvious toxic-side effects.
The Chinese medicine preparation of above-described tonifying YANG is not enough and lack or block its action pathway, hyposexuality, premature ejaculation, seminal emission and adeagus vascular blood and leak application in the medicine at the treatment androgen.
Above-mentioned each component is made the preparation method of the Chinese medicine preparation of tonifying YANG of the present invention:
1, the preparation method of oral liquid:
(1) gets by weight ratio Herba Pileae Scriptae, bar halberd, Radix Dipsaci, Fructus Psoraleae, the Radix Astragali, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Cortex Eucommiae, Rhizoma Curculiginis, Radix Ginseng, Poria, Radix Salviae Miltiorrhizae and Herba Cistanches, add 5-8 times of weight decocting and boil twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid, add an amount of syrup, mixing, fill, sterilization gets the finished product oral liquid, product called after of the present invention: emerging positive oral liquid.
2, the preparation method of granule:
(1) gets by weight ratio Herba Pileae Scriptae, bar halberd, Radix Dipsaci, Fructus Psoraleae, the Radix Astragali, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Cortex Eucommiae, Rhizoma Curculiginis, Radix Ginseng, Poria, Radix Salviae Miltiorrhizae and Herba Cistanches, add 5-8 times of water gaging and decoct twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid and concentrate, powder F gets dry extract;
(6) get intermediate products dried cream powder F and appropriate amount of auxiliary materials mixing, granulate, drying, packing gets the finished particle agent, product called after of the present invention: emerging positive granule.
3, the preparation method of capsule:
(1) gets by weight ratio Herba Pileae Scriptae, bar halberd, Radix Dipsaci, Fructus Psoraleae, the Radix Astragali, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Cortex Eucommiae, Rhizoma Curculiginis, Radix Ginseng, Poria, Radix Salviae Miltiorrhizae and Herba Cistanches, add 5-8 times of weight decocting and boil twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid and concentrate, spray drying, powder F gets dry extract;
(6) get intermediate products F and appropriate amount of auxiliary materials mixing, granulate, encapsulated, In Aluminium Foil Packing, packing gets the finished capsule product agent, product called after of the present invention: emerging positive capsule.
4, the preparation method of tablet:
(1) gets by weight ratio Herba Pileae Scriptae, bar halberd, Radix Dipsaci, Fructus Psoraleae, the Radix Astragali, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Cortex Eucommiae, Rhizoma Curculiginis, Radix Ginseng, Poria, Radix Salviae Miltiorrhizae and Herba Cistanches, add 5-8 times of weight decocting and boil twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid and concentrate, spray drying, powder F gets dry extract;
(6) get intermediate products dried cream powder F and mix with an amount of auxiliary grain, granulate, tabletting, packing gets finished tablet, emerging positive agent.
5, the preparation process of medicated wine is as follows:
(1) gets by weight ratio Herba Pileae Scriptae, bar halberd, Radix Dipsaci, Fructus Psoraleae, the Radix Astragali, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Cortex Eucommiae, Rhizoma Curculiginis, Radix Ginseng, Poria, Radix Salviae Miltiorrhizae and Herba Cistanches, be cut into the thin slice that thickness is the 1-2 millimeter;
(2) the grain brew wine with the 30-50% alcoholic strength of volumetric concentration is put in ceramic pot or the vial;
(3) medicine of thinly slicing is steeped in the grain brew wine; Per 100 gram medicines are with grain brew wine 0.6-1.5 liter.
(4) medicated wine is placed room temperature or cellar preserve more than 3 months, obtain product.
Note, should not use the metallic articles such as aluminium alloy, ashbury metal or ironware.The drinking vessel that uses should have lid, with pollutions such as the volatilization that prevents wine and dusts.Ceramic vessel has protection against the tide, anti-dry, lucifuge, guarantor's gas, and is difficult for and the advantages such as medicine generation chemical reaction, and profile is simple and unsophisticated attractive in appearance, has cultural features.But poorer than glass aspect impermeable.The glass drinking vessel is economic, obtains easily, is family's self-control medicated wine container commonly used.But glass has the characteristics that absorb heat, and transparent printing opacity, causes easily the unstable of effective ingredient in the medicated wine, the impact storage.It is good generally should selecting the dark glass drinking vessel.After medicated wine completes, should in time bottle or contain altar, drinking vessel is suitable for reading will to be sealed, and fume is leaked, and prevents that air from contacting with medicated wine, in order to avoid oxidation of drug and pollution.The medicated wine of sealing bottleneck should be placed on the place of shady and cool drying and lucifuge.When taking, with drink with falling, after immediately with bottleneck or the sealing of altar mouth.
Prescription Herba Pileae Scriptae of the present invention: slightly warm in nature, bitter in the mouth, suffering, anti-inflammation, dispelling wind and removing obstruction in the collateral, blood circulation promoting and dispersing pathogen accumulation; Bar halberd: acrid in the mouth, sweet, slightly warm in nature; Return liver, kidney channel; The body profit is mended and double faling apart; Special effect with strong vim and vigour, bone and muscle strengthening, method rheumatism, kidney-yang nourishing; Radix Dipsaci: bitter in the mouth, suffering, slightly warm in nature, return liver, kidney channel, invigorating the liver and kidney, bone and muscle strengthening, blood circulation regulating, continuous folding to hinder, end metrorrhagia; Fructus Psoraleae: acrid in the mouth; Bitter; Fructus Psoraleae warm in nature (5) kidney; Pericardium; Spleen; Stomach; Lung meridian has reinforcing the kidney and supporting YANG; Helping inspiration to relieve asthma; Warming spleen and stopping diarrha; The Radix Astragali: have invigorating QI to consolidate the body surface resistance, diuresis poison holding, QI invigorating invigorating middle warmer; Radix Polygoni Multiflori: property is bitter, sweet, puckery, warm, returns liver, the heart, kidney channel to have invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening, blood fat reducing, antidotal effect; Radix Angelicae Sinensis is sweet, hot, and temperature is returned liver, the heart, spleen channel, and effect is enriched blood, and invigorates blood circulation regulating menstruation, pain relieving, intestine moistening; The Cortex Eucommiae: Gan Weixin, temperature is regulated the flow of vital energy and is enriched blood; Rhizoma Curculiginis: suffering, temperature, poisonous, have the kidney warming sun, strengthening bone and muscle; Radix Ginseng: sweet, the little hardship of property, tepor, strongly invigorating primordial QI, invigorating the spleen to benefit the lung; Poria: sweet in the mouth, light, property is flat.Heat clearing away is arranged, dehumidifying, detoxifcation, the function in sharp joint; Radix Salviae Miltiorrhizae: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, relieving restlessness clears away heart-fire; Herba Cistanches: sweet in the mouth, salty, warm in nature, return kidney, large intestine channel, matter profit meat is thick, and is calm and fall; Has kidney-replenishing, benefiting essence-blood, the effect of loosening bowel to relieve constipation.More than all medicines join five through science and have and promote the testis tissue hypertrophy, not enough and lack or block its action pathway therapeutical effect effect to androgen, be used for the restorative functional treatments of kidney yang virtual loss such as sexual impotence, premature ejaculation, seminal emission.
The instructions of taking of product of the present invention:
Oral liquid, every day 2 to 3 times, each 10ml; Capsule, every day 2 to 3 times, 2 of every days; Granule, every day 2 to 3 times, each 1 bag, every bag 7 gram; Tablet, every day 2 to 3 times, each 2 to 3, every 0.3 gram.Medicated wine, each 50-100 milliliter, every day 1-2 time.
The invention has the beneficial effects as follows:
1, the present invention is that pure Chinese medicine is raw material, through scientific composition, makes with extra care and forms drink without any side effects.Organic disease there is significant curative effect, can reaches the treating both the principal and secondary aspects of a disease effect.
2, have obvious promotion testis tissue hypertrophy, not enough and lack or block its action pathway therapeutical effect to androgen; Be used for the restorative functions of kidney yang virtual loss such as sexual impotence, premature ejaculation, seminal emission.
3, cause sexual impotence because suffering from the treatment of vascular hypertension long-term taking propranolol, have obvious sexual function and recover.
4, the present invention fills a prescription simply, produce easy, patient's taking convenience, evident in efficacy.
The specific embodiment
Embodiment 1:
The preparation method of oral liquid:
(1) gets by weight ratio Herba Pileae Scriptae 10, bar halberd 10, Radix Dipsaci 10, Fructus Psoraleae 10, the Radix Astragali 10, Radix Polygoni Multiflori 10, Radix Angelicae Sinensis 5, the Cortex Eucommiae 10, Rhizoma Curculiginis 10, Radix Ginseng 5, Poria 10, Radix Salviae Miltiorrhizae 10 and Herba Cistanches 10, adding 5-8 times of water gaging decocts twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid, add an amount of syrup, mixing, fill, sterilization gets the finished product oral liquid, product called after of the present invention: emerging positive oral liquid.
Embodiment 2:
The preparation method of granule:
(1) gets by weight ratio Herba Pileae Scriptae 15, bar halberd 15, Radix Dipsaci 15, Fructus Psoraleae 15, the Radix Astragali 15, Radix Polygoni Multiflori 15, Radix Angelicae Sinensis 7, the Cortex Eucommiae 15, Rhizoma Curculiginis 15, Radix Ginseng 10, Poria 15, Radix Salviae Miltiorrhizae 15 and Herba Cistanches 15, adding 5-8 times of water gaging decocts twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid and concentrate, powder F gets dry extract;
(6) get intermediate products dried cream powder F and appropriate amount of auxiliary materials mixing, granulate, drying, packing gets the finished particle agent, product called after of the present invention: emerging positive granule.
Embodiment 3:
The preparation method of capsule:
(1) gets by weight ratio Herba Pileae Scriptae 20, bar halberd 20, Radix Dipsaci 20, Fructus Psoraleae 20, the Radix Astragali 20, Radix Polygoni Multiflori 20, Radix Angelicae Sinensis 8, the Cortex Eucommiae 20, Rhizoma Curculiginis 20, Radix Ginseng 15, Poria 20, Radix Salviae Miltiorrhizae 20 and Herba Cistanches 20, adding 5-8 times of water gaging decocts twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid and concentrate, spray drying, powder F gets dry extract;
(6) get intermediate products F and appropriate amount of auxiliary materials mixing, granulate, encapsulated, In Aluminium Foil Packing, packing gets the finished capsule product agent, product called after of the present invention: emerging positive capsule.
Embodiment 4:
The preparation method of tablet:
(1) gets by weight ratio Herba Pileae Scriptae 30, bar halberd 30, Radix Dipsaci 30, Fructus Psoraleae 30, the Radix Astragali 30, Radix Polygoni Multiflori 30, Radix Angelicae Sinensis 10, the Cortex Eucommiae 30, Rhizoma Curculiginis 30, Radix Ginseng 20, Poria 30, Radix Salviae Miltiorrhizae 30 and Herba Cistanches 30, adding 5-8 times of water gaging decocts twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid and concentrate, spray drying, powder F gets dry extract;
(6) get intermediate products dried cream powder F and mix with an amount of auxiliary grain, granulate, tabletting, packing gets finished tablet, emerging positive agent.
Embodiment 5:
The preparation process of medicated wine is as follows:
(1) gets by weight ratio Herba Pileae Scriptae 25, bar halberd 25, Radix Dipsaci 25, Fructus Psoraleae 25, the Radix Astragali 25, Radix Polygoni Multiflori 25, Radix Angelicae Sinensis 10, the Cortex Eucommiae 25, Rhizoma Curculiginis 25, Radix Ginseng 15, Poria 25, Radix Salviae Miltiorrhizae 20 and Herba Cistanches 20, be cut into the thin slice that thickness is the 1-2 millimeter;
(2) the grain brew wine with the 30-50% alcoholic strength of volumetric concentration is put in ceramic pot or the vial;
(3) medicine of thinly slicing is steeped in the grain brew wine; Per 100 gram medicines are with grain brew wine 1-1.5 liter.
(4) medicated wine is placed room temperature or cellar preserve more than 3 months, obtain product.
Application Example
Case 1:
Mr. Jia, 32 years old, pit hole village, good farmland, Luchuan County town expanded the grand peasant of team.Married, and can not have sexual intercourse because of sexual impotence after marriage in 1994.Divorce in 1996 oneself is seen the ground large hospital diagnosis and treatment such as Guangzhou, Chengdu afterwards, and is all invalid.The beginning of this year, there is blood vessel to leak at the Andriatrics Dept. inspection of Chengdu medical university, confirmation cavernous body of penis.But treat at the end, and do cavernosography the Guangxi District workers' hospital April in this year, confirms that bright stem spongy body left foot vein leaks.By taking emerging positive drink, 1 course for the treatment of, penis begins that erection is arranged, and continues later on to take medicine, and the erection effect strengthens day by day, and through taking medicine 45 days, erection is close to normal.
Case 2:
Mr. Liu, 28 years old, that grand secondary school teachers of Nanning suburb.Found day by day anorthosis of the original penis that erects in 1998.The end of the year 1999, intending examining in certain hospital is penile vein blood leakage property sexual impotence, and does the deep dorsal vein of penis ligation.Postoperative once slightly can erect in one month, but all can not surpass 90 degree, and was rear because of financial difficulties, fail to continue to take medicine, rear penis does not actively rise again gradually, freely takes emerging positive drink after 20 days afterwards, bright stem can erect again, and also in continuing to take medicine, existing oneself recovers normal now.
Case 3:
Mr. Huang, 62 years old, the retired cadre of Nanning City telecommunication bureau was because suffering from vascular hypertension, long-term taking antihypertensive drug.And causing sexual impotence 4 years, spirit is very worried, affects goodwill as between spouses.Once sought medical advice everywhere and take medicine, market treatment sexual impotence medicine on sale is all taken, and is all invalid.After take upon somebody's introduction emerging positive drink, erection is 6 minutes after 2 courses for the treatment of, continues to take 2 courses for the treatment of afterwards, sexual function recovers normally fully, thereupon also blood pressure lowering of hypertension.
Case 4:
Mr. Wen, 60 years old, certain epidemic prevention station associate chief physician, sleep disorder 12 years adds that work and study are nervous.Sexual function is extremely descended, can't have sexual intercourse, depression, through taking emerging positive drink after 2 courses for the treatment of, it is normal that sleep recovers, and energetic, it is normal that sexual function also recovers.
Case 5:
Mr. Fang, 35 years old, the workman of the green too plastic molding and processing plant in Nanning, an existing son, rear because of asthenia of renal yang, damage of kidney-YIN, deficiency of both the heart and spleen, fear of cold, and suffer from asthma, sexual disorder, sexual impotence 5 years.Seek medical advice everywhere and take medicine.Treatment sexual impotence medicine has all been taken in the city, but all invalid, after take 2 courses for the treatment of of emerging positive drink.Body constitution strengthens, and is radiant with vigour, energetic, and asthma disappears, and it is normal that sexual function recovers fully.
Case 6:
Mr. Huang, 76 years old, the retired cadre of Nanning City Construction Bank, remarried, the man and wife is too large because of the age gap distance, and Mr. Huang is conscious unable to do what one wishes, can't have sexual intercourse.After take upon somebody's introduction emerging positive drink after 20 days, begin to take effect, continue to take medicine, sexual function improves gradually, pleases oneself.
Case 7:
Mr. Du, 45 years old, the cadre of Nanning City hospital.Because drinking for a long time, add that rhythm of life is nervous, fatigue.Sexual disorder occurs, sexual impotence 8 months is taken emerging positive drink after 20 days by introduction, has recovered in the past sexual life.
Case 8:
Mr. Mo, 30 years old, the Tiandeng County peasant can not marry because of sexual impotence, mood is very worried, through take one the course for the treatment of sexual function recover fully normally, given birth to a son after the marriage.
Claims (9)
1. the Chinese medicine preparation of a tonifying YANG, it is characterized in that: this Chinese medicine preparation is to be made by the raw material of Chinese medicine of following parts by weight:
Herba Pileae Scriptae 10-30; Bar halberd 10-30;
Radix Dipsaci 10-30; Fructus Psoraleae 10-30;
Radix Astragali 10-30; Radix Polygoni Multiflori 10-30;
Radix Angelicae Sinensis 5-10; Cortex Eucommiae 10-30;
Rhizoma Curculiginis 10-30; Radix Ginseng 5-20;
Poria 10-30; Radix Salviae Miltiorrhizae 10-30;
Herba Cistanches 10-30.
2. the Chinese medicine preparation of tonifying YANG according to claim 1 is characterized in that: but the Chinese medicine preparation of described tonifying YANG is the dosage form of oral liquid, granule, capsule, tablet or other pharmacy.
3. the Chinese medicine preparation of tonifying YANG according to claim 1, it is characterized in that: the Chinese medicine preparation of described tonifying YANG is medicated wine.
According to claim 1 with the production method of the Chinese medicine preparation of 2 described tonifying YANGs, it is characterized in that: the preparation process of described oral liquid is as follows:
(1) gets by weight ratio Herba Pileae Scriptae, bar halberd, Radix Dipsaci, Fructus Psoraleae, the Radix Astragali, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Cortex Eucommiae, Rhizoma Curculiginis, Radix Ginseng, Poria, Radix Salviae Miltiorrhizae and Herba Cistanches, add 5-8 times of weight decocting and boil twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid, add an amount of syrup, mixing, fill, sterilization gets the finished product oral liquid.
According to claim 1 with the production method of the Chinese medicine preparation of 2 described tonifying YANGs, it is characterized in that: the preparation process of described granule is as follows:
(1) gets by weight ratio Herba Pileae Scriptae, bar halberd, Radix Dipsaci, Fructus Psoraleae, the Radix Astragali, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Cortex Eucommiae, Rhizoma Curculiginis, Radix Ginseng, Poria, Radix Salviae Miltiorrhizae and Herba Cistanches, add 5-8 times of weight decocting and boil twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid and concentrate, powder F gets dry extract;
(6) get intermediate products dried cream powder F and appropriate amount of auxiliary materials mixing, granulate, drying, packing gets the finished particle agent.
According to claim 1 with the production method of the Chinese medicine preparation of 2 described tonifying YANGs, it is characterized in that: the preparation process of described capsule is as follows:
(1) gets by weight ratio Herba Pileae Scriptae, bar halberd, Radix Dipsaci, Fructus Psoraleae, the Radix Astragali, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Cortex Eucommiae, Rhizoma Curculiginis, Radix Ginseng, Poria, Radix Salviae Miltiorrhizae and Herba Cistanches, add 5-8 times of weight decocting and boil twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid and concentrate, spray drying, powder F gets dry extract;
(6) get intermediate products F and appropriate amount of auxiliary materials mixing, granulate, encapsulated, In Aluminium Foil Packing, packing gets the finished capsule product agent.
According to claim 1 with the production method of the Chinese medicine preparation of 2 described tonifying YANGs, it is characterized in that: the preparation process of described tablet is as follows:
(1) gets by weight ratio Herba Pileae Scriptae, bar halberd, Radix Dipsaci, Fructus Psoraleae, the Radix Astragali, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Cortex Eucommiae, Rhizoma Curculiginis, Radix Ginseng, Poria, Radix Salviae Miltiorrhizae and Herba Cistanches, add 5-8 times of weight decocting and boil twice, each 1-2 hour, merge into A liquid;
(2) with above medicinal liquid A liquid, heating is concentrated, gets concentrated solution B;
(3) after the B cooling, add the 75-95% ethanol waters of 3 times of amount volumetric concentrations, mixing in 4 ℃ to 8 ℃ refrigerators or the icebox, left standstill 16-24 hour, filtered, and went precipitation;
(4) filtrate recycling ethanol is placed on above-mentioned filtrate in the alcohol recovering device, heating recovery ethanol, and the medicinal liquid behind the Recycled ethanol, heating is concentrated, and the residual a small amount of ethanol that volatilizees gets medicinal liquid C;
(5) get C liquid and concentrate, spray drying, powder F gets dry extract;
(6) get intermediate products dried cream powder F and mix with an amount of auxiliary grain, granulate, tabletting, packing gets finished tablet.
According to claim 1 with the production method of the Chinese medicine preparation of 3 described tonifying YANGs, it is characterized in that: the preparation process of described medicated wine is as follows:
(1) gets by weight ratio Herba Pileae Scriptae, bar halberd, Radix Dipsaci, Fructus Psoraleae, the Radix Astragali, Radix Polygoni Multiflori, Radix Angelicae Sinensis, the Cortex Eucommiae, Rhizoma Curculiginis, Radix Ginseng, Poria, Radix Salviae Miltiorrhizae and Herba Cistanches, be cut into the thin slice that thickness is the 1-2 millimeter;
(2) the grain brew wine with the 30-50% alcoholic strength of volumetric concentration is put in ceramic pot or the vial;
(3) medicine of thinly slicing is steeped in the grain brew wine; Per 100 gram medicines are with grain brew wine 0.6-1.5 liter;
(4) medicated wine is placed room temperature or cellar preserve more than 3 months, obtain product.
9. the purposes of the Chinese medicine preparation of tonifying YANG claimed in claim 1 is characterized in that: this Chinese medicine preparation is not enough and lack or block its action pathway, hyposexuality, premature ejaculation, seminal emission and adeagus vascular blood and leak application in the medicine at preparation treatment androgen.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210453272.8A CN102908470B (en) | 2012-11-13 | 2012-11-13 | Chinese materia medica preparation for tonifying Yang and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210453272.8A CN102908470B (en) | 2012-11-13 | 2012-11-13 | Chinese materia medica preparation for tonifying Yang and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102908470A true CN102908470A (en) | 2013-02-06 |
| CN102908470B CN102908470B (en) | 2014-09-24 |
Family
ID=47607203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210453272.8A Expired - Fee Related CN102908470B (en) | 2012-11-13 | 2012-11-13 | Chinese materia medica preparation for tonifying Yang and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102908470B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110522844A (en) * | 2019-07-12 | 2019-12-03 | 王宝建 | A kind of Chinese medicine preparation and preparation method thereof for treating impotence |
| TWI693939B (en) * | 2018-08-15 | 2020-05-21 | 大陸商通化特立杰爾醫藥技術推廣服務有限公司 | Composition for invigorating kidney and strengthening yang, preparation method and application thereof |
| CN112603988A (en) * | 2021-01-14 | 2021-04-06 | 无锡中大影像科技有限公司 | Liver and kidney capsule |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660404A (en) * | 2005-01-19 | 2005-08-31 | 雷小平 | Health product of preserving health, invigorating the kidney and supporting yang for male |
-
2012
- 2012-11-13 CN CN201210453272.8A patent/CN102908470B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1660404A (en) * | 2005-01-19 | 2005-08-31 | 雷小平 | Health product of preserving health, invigorating the kidney and supporting yang for male |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI693939B (en) * | 2018-08-15 | 2020-05-21 | 大陸商通化特立杰爾醫藥技術推廣服務有限公司 | Composition for invigorating kidney and strengthening yang, preparation method and application thereof |
| CN110522844A (en) * | 2019-07-12 | 2019-12-03 | 王宝建 | A kind of Chinese medicine preparation and preparation method thereof for treating impotence |
| CN112603988A (en) * | 2021-01-14 | 2021-04-06 | 无锡中大影像科技有限公司 | Liver and kidney capsule |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102908470B (en) | 2014-09-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103169881B (en) | Chinese medicament health product for supplementing female hormone for women during menopause and preparation method thereof | |
| CN104645186A (en) | Traditional Chinese medicine composition for strengthening physique and improving immunity and preparation method thereof | |
| CN101579471B (en) | Medicine for curing diabetes | |
| CN101912551B (en) | Miscarriage-prevention Chinese medicinal composition | |
| CN102908470B (en) | Chinese materia medica preparation for tonifying Yang and preparation method thereof | |
| CN105641466A (en) | Traditional Chinese medicine composition for invigorating kidney and strengthening yang and preparing method thereof | |
| CN115779064B (en) | Radix astragali strengthening square, preparation and application thereof | |
| CN104043077A (en) | Traditional Chinese medicine composition for tonifying qi and nourishing blood | |
| CN106215118A (en) | Antineoplastic health preparation and preparation method thereof | |
| CN105395842A (en) | Traditional Chinese medicine composition for treating diabetes and oral preparation and preparation method thereof | |
| CN104258300A (en) | Traditional Chinese medicine preparation for treating apoplexy sequela due to vital energy deficiency and blood stasis and preparation method of traditional Chinese medicine preparation | |
| CN104857271A (en) | Traditional Chinese medicine decoction piece combination preparation enhancing body immunity, preparation method therefor and combination package | |
| CN102091254B (en) | Traditional Chinese medicine composition for relieving swelling after cosmetic surgery and preparation method thereof | |
| CN104983899A (en) | Traditional Chinese medicine composition for treating female deficiency of qi and blood | |
| CN104689067A (en) | Traditional Chinese medicine composition for treating sexual precocity and application thereof | |
| CN104258224A (en) | Schisandra chinensis oral solution for treating lung-and-kidney yin-deficiency type chronic bronchitis and preparation method thereof | |
| CN104352705A (en) | Drug composition for treating lobular hyperplasia of mammary glands and preparation method thereof | |
| CN103417836B (en) | Chinese medicine composition for the treatment of tumor and preparation method thereof | |
| CN102225148B (en) | Health care wine for strengthening physique and male sexual functions | |
| CN105944036A (en) | Traditional Chinese medicine composition for adjuvant therapy for depression | |
| CN105664143A (en) | Medicinal composition with body building and yang strengthening functions and preparation method thereof | |
| CN105663383A (en) | Traditional Chinese medicine composition with body building and yang strengthening functions | |
| CN105250903A (en) | Traditional Chinese medicine physiotherapeutic liquid for treating numbness of limbs and preparation method of traditional Chinese medicine physiotherapeutic liquid | |
| CN111821385A (en) | Health-preserving health wine | |
| CN112891505A (en) | Spleen-tonifying and kidney-tonifying composition, preparation method and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP02 | Change in the address of a patent holder |
Address after: 546100 No.137, Chengbei Road, Wuxuan Town, Wuxuan County, Laibin City, Guangxi Zhuang Autonomous Region Patentee after: Li Jianmin Address before: 532300, 272, Minsheng street, Peach Town, Chongzuo, the Guangxi Zhuang Autonomous Region, Xinxian County Patentee before: Li Jianmin |
|
| CP02 | Change in the address of a patent holder | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140924 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |