CN102895551B - Traditional Chinese medicine for treating chronic renal failure - Google Patents
Traditional Chinese medicine for treating chronic renal failure Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating chronic renal failure. The traditional Chinese medicine is prepared from the following medicinal materials in parts by weight: 10 parts of rhizoma polygonati odorati, 8 parts of polygonum multiflorum, 14 parts of white paeony root, 5 parts of morinda officinalis, 6 parts of semen cuscutae chinensis, 8 parts of eucommia ulmoides, 3 parts of cornu cervi pantotrichum, 12 parts of dried orange peel, 9 parts of root of Chinese thorowax, 8 parts of dangshen, 12 parts of radix astragali, 14 parts of dioscorea opposita, 15 parts of honey, 8 parts of rhizoma imperatae, 10 parts of polygonatum sibiricum, 10 parts of honeysuckle and 14 parts of cicada slough. Clinical experiments show that the traditional Chinese medicine can safely and effectively treat chronic renal failure.
Description
Technical field
The present invention relates to a kind of Chinese medicine, be specifically related to a kind of Chinese medicine for the treatment of chronic renal failure.
Background technology
Chronic renal failure (chronic renal failure, CRF) refer to that various nephropathys cause the gradual irreversibility of above-mentioned three large functions of kidney to go down, until the clinical syndrome that the series of symptoms that afunction occurs and metabolism disorder form is called for short chronic kidney hypofunction.Enter 21 century, chronic renal failure has become in the world wide one of the serious threat human health large public hazards after cardiovascular and cerebrovascular disease, tumor and diabetes.Chronic kidney hypofunction can be divided into following four-stage: the compensatory phase of (1) renal function; (2) renal function loses the compensatory phase; (3) renal failure stage (preuremic stage); (4) Uremic.
Still lack at present the effective medicine of generally recognized as safe for chronic renal failure.
The present Research of the related medical material of Chinese medicine of the present invention is as follows:
Rhizoma Polygonati Odorati [source] is the Liliaceae herbaceos perennial.Rhizome is horizontal walks meat yellow-white, the most fibrous roots of close life.Dry, or after steaming thoroughly, rub to translucent, dry, cut sheet or section usefulness.[function cures mainly] nourishing YIN and moistening the lung; Nourishing the stomach to promote the production of body fluid.Cough caused by dryness; Chronic cough; The dry throat and mouth of the cloudy liquid consumption of calentura wound; Interior-heat is quenched one's thirst; Deficiency of YIN diseases caused by exogenous pathogenic factor; Dizzy dizzy; Muscle arteries and veins spasm and pain.
Radix Polygoni Multiflori [source] is the perennial winding of Polygonaceae liana.Root is elongated, the loose tuber of terminal one-tenth, and the appearance bronzing is to crineous.But the tuber of plant, rattan and leaf be hyoscine all.[function cures mainly] detoxifcation, loosening bowel to relieve constipation, eliminating carbuncle; Enrich and benefit essence and blood, black beard and hair, bone and muscle strengthening, invigorating the liver and kidney.Promote hemopoietic function, strengthen immunologic function.
The Radix Paeoniae Alba [source] is the root of dicotyledon medicine ranunculaceae plant Radix Paeoniae (cultigen).The Peony Root of planting 3～4 years is removed rhizome and fibrous root, cleans, and scrapes off rough bark, enters in the boiling water and slightly boils, and the Chinese herbaceous peony root is felt like jelly, and pulls out and dries.[function cures mainly] nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.Control the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
Radix Morindae Officinalis [source] is the dry root of dicotyledon Rubiaceae (Rubiaceae) Radix Morindae Officinalis (Morinda officinalis How.).[function cures mainly] cures mainly that impotence and seminal emission, cold womb are infertile, menoxenia, few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity are soft.
The seed of Semen Cuscutae [source] dicotyledon scammonia section plant Semen Cuscutae, southern Semen Cuscutae, cuscuta japonica Choisy etc.[function cures mainly] has the effect of the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, solid tire stopping leak.
The dry bark of the Cortex Eucommiae [source] the Eucommiaceae plant Cortex Eucommiae (Eucommia ulmoides Oliver) is Chinese famous and precious tonic herb.[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, blood pressure lowering, many effects such as antiabortive.
When the tender angle of Cornu Cervi Pantotrichum [source] stag did not grow up to os osseum, the band fine hair contained blood, is called Cornu Cervi Pantotrichum.[function cures mainly] returns kidney, Liver Channel.Marrow is mended in invigorating kidney-YANG, and bone and muscle strengthening transfers punching to appoint, the holder sore.Cure mainly suffer from a deficiency of the kidney, dizzy, deaf, the diseases such as order is dark, sexual impotence, spermatorrhea, cold womb are infertile, weakness and emaciation, Mental fatigue, fear of cold, spinal column cold type of pain, muscles and bones flaccidity are soft, bleeding not during menses, carbuncle of yin nature is not held back and prolonged illness is deficient.
The mature peel of Pericarpium Citri Reticulatae [source] rutaceae orange and variety thereof.[function cures mainly] appetizing of regulating the flow of vital energy, drying dampness to eliminate phlegm is controlled the spleen-stomach disease.
Radix Bupleuri [source] another name: Asia puecon recklessly, smoke clearind deficient heat Chinese medicine.[function cures mainly] expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.
Radix Codonopsis [source] Chinese medicine Radix Codonopsis is that campanulaceae herbaceos perennial [function cures mainly] has invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.Enhancing immunity, blood vessel dilating, blood pressure lowering, improve microcirculation, strengthen the effects such as hemopoietic function
The Radix Astragali [source] is the root of leguminous plant Radix Astagali or Radix Astragali.Remove fibrous root and root head, dry, section is given birth to and is used or processed with honey usefulness.[function cures mainly] has the enhancing human body immunity function, protects the liver, diuresis, defying age, anti-stress, blood pressure lowering and antibacterial action more widely.
Rhizoma Dioscoreae [source] herbaceos perennial, stem is overgrow, and often is with purple, and tuber is cylindrical, and leaf is to life, and is avette or oval, flower milky, dioecism.Starch-containing and the protein of tuber.[function cures mainly] spleen reinforcing nourishing the stomach, the lung benefiting that promotes the production of body fluid, the kidney invigorating arresting seminal emission.Be used for insufficiency of the spleen lack of appetite, incessant chronic diarrhea, the deficiency of the lung is breathed with cough, emission due to deficiency of the kidney, leukorrhagia, frequent micturition, deficiency-heat is quenched one's thirst.
The honey of Mel [source] nectar brew in Nidus Vespae that what to be the insecticide Apis adopt from the spending of flowering plant.[function cures mainly] improves the composition of blood, promotes heart and brain and vascular function, regains one's strength of body, and allaying tiredness builds up one's resistance to disease.
Rhizoma Imperatae [source] grass perennial herb Herba Imperatae (formal name used at school: rhizome Imperata cylindrica).Two seasons of spring and autumn excavate.Dry.Remove fibrous root and membranous sheath, cutting is given birth to and is used or parch to black usefulness.[function cures mainly] removing heat from blood, hemostasis, heat clearing away, diuresis.Control the calentura excessive thirst.
Rhizoma Polygonati [source] has another name called Rhizoma Polygonati Cirrhifolii, Caput Gallus domesticus ginseng.The dry rhizome of liliaceous plant Yunnan Rhizoma Polygonati, Rhizoma Polygonati or Polygonatum cyrtonema Hua.Be used as medicine with rhizome.[function cures mainly] has boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney benefiting functions.Be used for the treatment of weakness of the spleen and stomach, fatigue and asthenia, xerostomia lack of appetite, deficiency of the lung cough caused by dryness, asthenia of essence and blood, the interior-heat disease such as quench one's thirst.
Flos Lonicerae [source] is Caprifoliaceae woodbine Radix Ophiopogonis and congener dry flower or the first flower of opening of band.The property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach.[source] antiinflammatory and analgesic, booster immunization function, blood fat reducing, antiendotoxin, resisting pathogenic microbes.
Exuviae shell when the nymph of Periostracum Cicadae [source] cicada Cryptotympana atrata Fabr. Cryptotympana pustulata Fabricius sprouts wings.The surface yellowish-brown, translucent, glossy.[function cures mainly] dispelling wind-heat, rash sore-throat relieving, removing nebula to improve visual acuity, expelling wind and relieving convulsion.Sore-throat relieving, rash, nebula removing, spasmolytic.Be used for anemopyretic cold, pharyngalgia, hoarseness, measles without adequate eruption, rubella pruritus, conjunctival congestion cataracta, convulsion with spasms, tetanus.
Summary of the invention
The present invention aims to provide a kind of Chinese medicine for the treatment of chronic renal failure, by selecting suitable medical material and proportioning thereof, reaches the purpose of safe and effective healing chronic renal failure.
In order to achieve the above object, the present invention is by the following technical solutions:
A kind of Chinese medicine for the treatment of chronic renal failure, it is characterized in that, be prepared from by the medical material of following weight proportion: 10 parts of Rhizoma Polygonati Odorati, 8 parts of Radix Polygoni Multiflori, 14 parts of the Radix Paeoniae Albas, 5 parts of Radix Morindae Officinaliss, 6 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 3 parts in Cornu Cervi Pantotrichum, 12 parts of Pericarpium Citri Reticulataes, 9 parts of Radix Bupleuri, 8 parts of Radix Codonopsis, 12 parts of the Radixs Astragali, 14 parts of Rhizoma Dioscoreaes, 15 parts of Mel, 8 parts of Rhizoma Imperataes, 10 parts of Rhizoma Polygonatis, 10 parts of Flos Loniceraes, 14 parts of Periostracum Cicadaes.
Below in conjunction with clinical experiment data declaration beneficial effect of the present invention:
1, physical data
The inventor collects the out-patient of 80 routine chronic renal failures in June, 2010-2011 altogether between year JIUYUE, age 12-47 year, course of disease 0.5-7.Be divided at random: treatment group 50 examples, blank group 30 examples.The data there was no significant differences such as two groups of ages, the state of an illness have comparability.
2, test method
2.1 the capsule that the oral the present invention for the treatment of group makes according to specific embodiment 1, sooner or later respectively once.30 days courses for the treatment of.
2.2 blank group oral placebo capsule, sooner or later respectively once.30 days courses for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterion of therapeutical effect
Recovery from illness: clinical symptoms all disappears, and the test chamber inspection is normal.Take a turn for the better: clinical symptom relief, the state of an illness is controlled, and lab testing improves or is normal.Invalid: clinical symptoms is without being clearly better or increasing the weight of.
3.2 treatment statistical result sees Table 1.
Table 1 liang group curative effect relatively
| Group | n | Recovery from illness | Take a turn for the better | Invalid | Total effective rate (%) |
| Treatment group | 50 | 10（20%） | 34（68%) | 6（12%) | 88% |
| Blank group | 30 | 0 | 5（16.7%） | 25（83.3%） | 16.7% |
As seen, the medicine that makes of the present invention can safe and effectively be controlled chronic renal failure.
The specific embodiment
In order to understand better and to implement the present invention, further specify the present invention below in conjunction with specific embodiment.
Specific embodiment 1
Take by weighing: Rhizoma Polygonati Odorati 10 grams, Radix Polygoni Multiflori 8 grams, the Radix Paeoniae Alba 14 grams, Radix Morindae Officinalis 5 grams, Semen Cuscutae 6 grams, the Cortex Eucommiae 8 grams, Cornu Cervi Pantotrichum 3 grams, Pericarpium Citri Reticulatae 12 grams, Radix Bupleuri 9 grams, Radix Codonopsis 8 grams, the Radix Astragali 12 grams, Rhizoma Dioscoreae 14 grams, Mel 15 grams, Rhizoma Imperatae 8 grams, Rhizoma Polygonati 10 grams, Flos Lonicerae 10 grams, Periostracum Cicadae 14 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, drying incapsulates shell, namely gets the capsule that meets 1 day consumption of normal adult.
Be used for the treatment of chronic renal failure.Oral, every bu is taken for twice sooner or later.
Specific embodiment 2
Take by weighing: Rhizoma Polygonati Odorati 10 grams, Radix Polygoni Multiflori 8 grams, the Radix Paeoniae Alba 14 grams, Radix Morindae Officinalis 5 grams, Semen Cuscutae 6 grams, the Cortex Eucommiae 8 grams, Cornu Cervi Pantotrichum 3 grams, Pericarpium Citri Reticulatae 12 grams, Radix Bupleuri 9 grams, Radix Codonopsis 8 grams, the Radix Astragali 12 grams, Rhizoma Dioscoreae 14 grams, Mel 15 grams, Rhizoma Imperatae 8 grams, Rhizoma Polygonati 10 grams, Flos Lonicerae 10 grams, Periostracum Cicadae 14 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, drying, concentrated, drying is pulverized, and namely gets the powder that meets 1 day consumption of normal adult.
Be used for the treatment of chronic renal failure.Oral, every bu is taken for twice sooner or later.
Specific embodiment 3
Take by weighing: Rhizoma Polygonati Odorati 10 grams, Radix Polygoni Multiflori 8 grams, the Radix Paeoniae Alba 14 grams, Radix Morindae Officinalis 5 grams, Semen Cuscutae 6 grams, the Cortex Eucommiae 8 grams, Cornu Cervi Pantotrichum 3 grams, Pericarpium Citri Reticulatae 12 grams, Radix Bupleuri 9 grams, Radix Codonopsis 8 grams, the Radix Astragali 12 grams, Rhizoma Dioscoreae 14 grams, Mel 15 grams, Rhizoma Imperatae 8 grams, Rhizoma Polygonati 10 grams, Flos Lonicerae 10 grams, Periostracum Cicadae 14 grams, add 8 times of water gagings, decocted 1.5 hours, and filtered; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, drying, drying adds an amount of dextrin and correctives again, granulates according to this area common process, and packing can make the granule that meets 1 day consumption of normal adult.
Be used for the treatment of chronic renal failure.Oral, every bu is taken for twice sooner or later.
Claims (1)
1. Chinese medicine for the treatment of chronic renal failure, it is characterized in that, be prepared from by the medical material of following weight proportion: 10 parts of Rhizoma Polygonati Odorati, 8 parts of Radix Polygoni Multiflori, 14 parts of the Radix Paeoniae Albas, 5 parts of Radix Morindae Officinaliss, 6 parts of Semen Cuscutae, 8 parts of the Cortexs Eucommiae, 3 parts in Cornu Cervi Pantotrichum, 12 parts of Pericarpium Citri Reticulataes, 9 parts of Radix Bupleuri, 8 parts of Radix Codonopsis, 12 parts of the Radixs Astragali, 14 parts of Rhizoma Dioscoreaes, 15 parts of Mel, 8 parts of Rhizoma Imperataes, 10 parts of Rhizoma Polygonatis, 10 parts of Flos Loniceraes, 14 parts of Periostracum Cicadaes.
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Effective date of registration: 20141215 Address after: 225500 No. 1 Su Zhong Road, Jiangyan District, Jiangsu, Taizhou Patentee after: JIANGSU SUZHONG PHARMACEUTICAL GROUP Co.,Ltd. Address before: 205, building 25, Shandong Institute of Business and Technology, 191 Binhai Middle Road, Laishan District, Shandong, Yantai 264005 Patentee before: Li Kai |
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Address after: No.1 Suzhong Road, Jiangyan District, Taizhou City, Jiangsu Province 225500 Patentee after: Suzhong Pharmaceutical Group Co.,Ltd. Address before: No.1 Suzhong Road, Jiangyan District, Taizhou City, Jiangsu Province 225500 Patentee before: JIANGSU SUZHONG PHARMACEUTICAL GROUP Co.,Ltd. |
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