CN102895425A - Bentonite-containing woundplaster - Google Patents

Bentonite-containing woundplaster Download PDF

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Publication number
CN102895425A
CN102895425A CN2012103269006A CN201210326900A CN102895425A CN 102895425 A CN102895425 A CN 102895425A CN 2012103269006 A CN2012103269006 A CN 2012103269006A CN 201210326900 A CN201210326900 A CN 201210326900A CN 102895425 A CN102895425 A CN 102895425A
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China
Prior art keywords
bentonite
adhesive bandage
woundplaster
wound
1000000ths
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CN2012103269006A
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CN102895425B (en
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俞铁民
张有连
张怀滨
姜建
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CHANG'AN RENHENG CHEMICAL Co Ltd
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CHANG'AN RENHENG CHEMICAL Co Ltd
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Abstract

The present invention relates to a bentonite-containing woundplaster, which is characterized in that an inner layer nonwoven gauze attached to a woundplaster is dipped with an agent on the basis of the general woundplaster, and the agent comprises bentonite. The woundplaster has a good blood clotting effect. The agent surface of the woundplaster is pasted on a skin trauma position, the bentonite in the woundplaster contacts blood to form a gel, and the gel can oppressively prevent the blood from further outflow so as to quickly stop bleeding. In addition, the bentonite can absorb bacteria in the wound so as to prevent bacterial propagation and wound infection, and the formed gel can be used as a protection layer for the wound surface and the surrounding so as to prevent external bacteria invasion.

Description

A kind ofly contain bentonitic adhesive bandage
Technical field
The invention belongs to field of medical products, particularly a kind ofly contain bentonitic adhesive bandage, have rapid blood coagulation and can prevent the wound infection effect.
Background technology
Existing adhesive bandage is mainly by a microscler adhesive plaster, and the centre is accompanied by the sliver formation that a fritter soaked the bactericidal antiphlogistic medicine, plays the isolation wound, is a kind of surgical medicine the most frequently used during people live.Adhesive bandage of the prior art cements wound easily.And if wound infects, adhesive bandage also might be formed with the environment that is beneficial to bacterial growth, causes the wound repeated infection, is difficult for healing.
Summary of the invention
In order to solve defects of the prior art, the invention provides and a kind ofly contain bentonitic adhesive bandage, but rapid blood coagulation and hemostasis, and can prevent wound infection.
A kind ofly contain bentonitic adhesive bandage, it is characterized in that, on the basis of general adhesive bandage, be attached on the internal layer nonwoven gauze of adhesive bandage and be impregnated with medicament, described medicament comprises bentonite.
Bentonitic Main Ingredients and Appearance is Montmorillonitum, is a kind of layered clay mineral matter that is comprised of two-layer silicon-oxy tetrahedron therebetween one deck alumina octahedral.In the forming process of bentonite ore, the silicon of part or aluminum are usually substituted by calcium at a low price or magnesium, have formed defective in bentonitic structure.After bentonite was met water, these fault locations moistened spreading easily by water intrusion, and bentonitic laminated structure is opened.Therefore, the bentonitic surface area that compares is very large, can reach 1000m 2/ g.And the bentonite absorption property is very good.
Adhesive bandage of the present invention has extraordinary Blood clotting.The medicament face of adhesive bandage is affixed on the skin trauma place, after the bentonite in the adhesive bandage runs into blood, can forms gel, can be repressive the further outflow of ground resistance hemostasis, thereby quick-acting haemostatic powder.On the other hand, bentonite can also adsorb the antibacterial in the wound, stops the breeding of antibacterial, prevents wound infection, and formed gel is in wound surface and can be used as protective layer all around, stops extraneous bacterial invasion.
In the present invention, bentonite can separately as the medicament of adhesive bandage, also can be used as medicament with other medicines.
Further, described medicament is comprised of bentonite, ingredient, water and glycerol, and its parts by weight are respectively: bentonite 50-80 part, ingredient 10-30 part, water 20-30 part, glycerol 10-20 part.
Further, described ingredient is one or more in Radix Scutellariae, Galla Chinensis or the Pollen Typhae.
Lead amount is less than 5/1000000ths in the described bentonite, and the content of cadmium is less than 3/1000000ths, and the content of arsenic is less than 2/1000000ths, and Hg content is less than 2/1000000ths, and the content of copper is less than 20/1000000ths.
Bentonite has blood coagulation, antibiotic effect, and absorption blood forms gel, plays the hemostasis effect; And the absorption antibacterial, prevent bacterial reproduction.Radix Scutellariae has antibiotic effect, and is inhibited to bacillus pyocyaneus, staphylococcus, Hemolytic streptococcus (α, β) etc.Galla Chinensis has the effect of hemostatic and antibacterial, and staphylococcus aureus, streptococcus are had obviously antibacterial, bactericidal action.Pollen Typhae has hemostasis, blood stasis dispelling, the effect such as treating stranguria.
Bentonite is mixed with Radix Scutellariae, Galla Chinensis or Pollen Typhae powder dispersion liquid, the dispersion liquid that bentonite can the adsorptive liquid shape, the control sustained release, make adhesive bandage to protect the wound effect more effectively lasting, promote wound healing.
Adhesive bandage of the present invention can prepare by the following method: with the bentonite aqueous dispersion, Radix Scutellariae, Galla Chinensis or Pollen Typhae disperse with glycerol, two kinds of dispersion liquid mix homogeneously, as impregnation liquid.After the medical non-woven gauze flooded in impregnation liquid, according to the production technology processing of general adhesive bandage.
The present invention utilizes bentonitic high absorption property, and separately as the adhesive bandage medicament, or the other medicines in adhesive bandage cooperate as medicament, all can obtain good effect with bentonite.Bentonite mainly plays three aspects: in adhesive bandage:
1, after the bentonite in the adhesive bandage runs into blood, can form gel, can be repressive the further outflow of ground resistance hemostasis, thereby quick-acting haemostatic powder.
2, bentonite can adsorb the antibacterial in the wound, stops the breeding of antibacterial, prevents wound infection; Formed gel is in wound surface and can be used as protective layer all around, stops extraneous bacterial invasion.
3, other medicament of all right adsorptive liquid shape of bentonite slowly discharges, and it is more lasting effective to make protecting of adhesive bandage create effect, promotes wound healing.
With the bentonitic adhesive bandage of interpolation of the present invention with do not add bentonitic common adhesive bandage and carry out clinical application effect relatively.Each 80 people of set of applications and matched group, but by aspect determine effects such as haemostatic effect, infection conditions, healing times.The result is as shown in the table.
Figure 422177DEST_PATH_IMAGE001
As can be seen from the above table, add bentonitic adhesive bandage from haemostatic effect, infection conditions, healing time aspect, obviously be better than not adding bentonitic common adhesive bandage.
Adhesive bandage of the present invention can be used for general skin injury wound, also can be used for the general wound.
The specific embodiment
Embodiment 1
50 parts bentonite is with 20 parts aqueous dispersion, as impregnation liquid.After getting medical gauze dipping, be cut into lamellar.Be pasted on the adhesive plaster, according to the production technology processing of general adhesive bandage.
Embodiment 2
80 parts bentonite is with 30 parts aqueous dispersion, as impregnation liquid.After getting medical gauze dipping, be pasted on the adhesive plaster after being cut into lamellar, according to the production technology processing of general adhesive bandage.
Embodiment 3
60 parts bentonite disperses with 20 parts water and 15 parts glycerol, makes impregnation liquid.Get and be pasted on the gauze after being cut into lamellar behind the medical gauze dipping, according to the production technology processing of general adhesive bandage.
Embodiment 4
50 parts bentonite is with 30 parts aqueous dispersion.5 parts Radix Scutellariae powder and and 5 parts Pollen Typhae, with 10 parts glycerol dispersion.With bentonite dispersion liquid and medicine dispersion liquid mix homogeneously, as impregnation liquid.Get medical gauze dipping, be pasted on the adhesive plaster after being cut into lamellar, according to the production technology processing of general adhesive bandage.
Embodiment 5
80 parts bentonite disperses with 20 parts water and 10 parts glycerol.10 parts Radix Scutellariae powder and and 20 parts Galla Chinensis, with 10 parts glycerol dispersion.Bentonite dispersion liquid and medicine dispersion liquid respectively with medical gauze dipping, are pasted on the adhesive plaster after being cut into lamellar.Flooded the gauze of bentonite dispersion liquid near the one side of adhesive plaster.

Claims (4)

1. one kind contains bentonitic adhesive bandage, it is characterized in that, on the basis of general adhesive bandage, is attached on the internal layer nonwoven gauze of adhesive bandage and is impregnated with medicament, and described medicament comprises bentonite.
2. adhesive bandage as claimed in claim 1 is characterized in that, described medicament is comprised of bentonite, ingredient, water and glycerol, and its parts by weight are respectively: bentonite 50-80 part, ingredient 10-30 part, water 20-30 part, glycerol 10-20 part.
3. adhesive bandage as claimed in claim 2 is characterized in that, described ingredient is one or more in Radix Scutellariae, Galla Chinensis or the Pollen Typhae.
4. adhesive bandage as claimed in claim 1 is characterized in that, lead amount is less than 5/1000000ths in the described bentonite, the content of cadmium is less than 3/1000000ths, the content of arsenic is less than 2/1000000ths, and Hg content is less than 2/1000000ths, and the content of copper is less than 20/1000000ths.
CN201210326900.6A 2012-09-06 2012-09-06 Bentonite-containing woundplaster Active CN102895425B (en)

Priority Applications (1)

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Application Number Priority Date Filing Date Title
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104000887A (en) * 2014-06-23 2014-08-27 青岛大学 Chinese herbal medicine dispensation for antibiosis of hands and skin
CN107050499A (en) * 2017-03-08 2017-08-18 安徽省伟业净化设备有限公司 One kind contains diatomaceous adhesive bandage
CN112516195A (en) * 2019-08-30 2021-03-19 西南交通大学 Anti-staphylococcus aureus and drug-resistant strain traditional Chinese medicine composition thereof, and preparation method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101450077A (en) * 2009-01-06 2009-06-10 浙江大学 Preparation method of external natural aluminosilicate emergency life-saving hemostatic
CN101683372A (en) * 2008-09-26 2010-03-31 天津市中宝制药有限公司 Chinese medicine patch with anti-inflammation and delactation functions and method for producing the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101683372A (en) * 2008-09-26 2010-03-31 天津市中宝制药有限公司 Chinese medicine patch with anti-inflammation and delactation functions and method for producing the same
CN101450077A (en) * 2009-01-06 2009-06-10 浙江大学 Preparation method of external natural aluminosilicate emergency life-saving hemostatic

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104000887A (en) * 2014-06-23 2014-08-27 青岛大学 Chinese herbal medicine dispensation for antibiosis of hands and skin
CN104000887B (en) * 2014-06-23 2016-01-20 青岛大学 A kind of herbal composite for hands, antibacterial skin
CN107050499A (en) * 2017-03-08 2017-08-18 安徽省伟业净化设备有限公司 One kind contains diatomaceous adhesive bandage
CN112516195A (en) * 2019-08-30 2021-03-19 西南交通大学 Anti-staphylococcus aureus and drug-resistant strain traditional Chinese medicine composition thereof, and preparation method and application thereof
CN112516195B (en) * 2019-08-30 2022-05-24 西南交通大学 Anti-staphylococcus aureus and drug-resistant strain traditional Chinese medicine composition thereof, and preparation method and application thereof

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Inventor after: Yu Tieming

Inventor after: Zhang Youlian

Inventor after: Zhang Huaibin

Inventor after: Jiang Jian

Inventor before: Yu Tiemin

Inventor before: Zhang Youlian

Inventor before: Zhang Huaibin

Inventor before: Jiang Jian

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Free format text: CORRECT: INVENTOR; FROM: YU TIEMIN ZHANG YOULIAN ZHANG HUAIBIN JIANG JIAN TO: YU TIEMING ZHANG YOULIAN ZHANG HUAIBIN JIANG JIAN