CN102872267A - Traditional Chinese medicine composition for resisting fatigue and tonifying kidney, and preparation method thereof - Google Patents
Traditional Chinese medicine composition for resisting fatigue and tonifying kidney, and preparation method thereof Download PDFInfo
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- CN102872267A CN102872267A CN2012103879030A CN201210387903A CN102872267A CN 102872267 A CN102872267 A CN 102872267A CN 2012103879030 A CN2012103879030 A CN 2012103879030A CN 201210387903 A CN201210387903 A CN 201210387903A CN 102872267 A CN102872267 A CN 102872267A
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Abstract
The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for resisting fatigue and tonifying kidney, and a preparation method thereof. The traditional Chinese medicine composition for resisting fatigue and tonifying kidney is prepared from the raw materials in parts by weight: 90-110 parts of cistanche, 90-110 parts of semen cuscutae, 70-80 parts of barbary wolfberry fruits, 25-35 parts of red ginseng, 25-35 parts of hippocampus and 5-15 parts of starch. The invention also provides the preparation method of the traditional Chinese medicine composition, and a clinical preparation of the traditional Chinese medicine composition. The traditional Chinese medicine composition has the functions of tonifying kidney, tonifying qi and nourishing blood, and can be a health care product used for diseases such as fatigue, soreness and weakness of waist and knees, dizziness, and the like.
Description
Technical field
The present invention relates to tcm field, relate to specifically a kind of Chinese medicine composition with resisting fatigue, kidney tonifying functions and preparation method thereof.
Background technology
Kidney belongs to the part of urinary system, and in Chinese medicine, kidney belongs to one of the five internal organs.The kidney being the origin of congenital constitution, is the congenital basic of human life, concerning human existence procreation.The kidney qi profit and loss except reaction kidney and relevant tissue health thereof whether, also represent vitality and be prosperous be a little less than.So-calledly in the disease of the suffering from a deficiency of the kidney performance suffer from a deficiency of the kidney, deficiency of the kidney, contained the qi-blood circulating of kidney and kidney channel, or function produces related organ-tissue with kidney, such as the problems such as urinary system, reproductive system of being correlated with, kidney alleged on part concept and the doctor trained in Western medicine anatomy is different.
Kidney is hidden first acquired essence, and kidney essense turns to kidney qi, wherein to body have warm, excite, excited, evaporate, seal actor such as hiding and restrict YIN-cold and be referred to as kidney yang, also be called Yuanyang, kidney-Yang, kidney-yang; To body have moist, quiet, being shaped and suppressing excessively the actor such as sun heat is referred to as kidney yin, also is called Kidney-Yin, Kidney-Yin, true water.Kidney yang can promote that the metabolism of human body is gasification, and the change of promotion essence and blood, body fluid is given birth to and made it to be converted into energy, and the process of the various physiological activities of human body is accelerated, and heat production increases, and is in high spirits; Kidney yin then suppresses or the excessive metabolic processes of reducing human, making essence and blood body fluid be converted into energy reduces, the process of the various physiological activities of human body slows down, heat production reduces relatively, and make poly-shaping of gas and be essence and blood body fluid, spirit also is tending towards keeping the two in quiet opposes each other and yet also complement each other, and common the adjusting controlled the function activity of human body and the metabolic process of essence and blood body fluid.In addition, because the quickening of modern life rhythm causes health to be overdrawed for a long time, make the running of health over loading ground, thereby cause kidney to lack taking a tonic or nourishing food to build up one's health and cross presenility, thereby the symptom of all discomforts occurs.
The traditional Chinese medical science thinks that suffer from a deficiency of the kidney minute deficiency of the kidney yin and insufficiency of kidney-YANG will be done different diagnosis and treatment according to different symptoms.Suffering from a deficiency of the kidney mostly is long-term accumulation and becomes disease, can't nourish because of the medicine of large benefits of using anxious for success, and the kidney invigorating and YANG supporting medicine of perhaps failing to understand with composition, and should slowly nurse one's health.The yang deficiency symptom: soreness of waist and knee joint, or back cold type of pain, aversion to cold and cold limbs, especially with lower limb for very; The vertigo, lethargy, pale complexion or dark; The fat tongue of light red tongue is white, deep and weak pulse; The easy impotence and premature ejaculation of male, the easy infertility of women; Or the stool chronic diarrhea is more than, aqueous-grainy diarrhea, Diarrhoea; Or edema, waist is following for very, by depression do not play abdominal part distending pain very then, cardiopalmus cough with asthma.Deficiency of YIN symptom: soreness of the waist and knees, two skelasthenia, vertigo and tinnitus, alopecia tooth pine, the night sweat insomnia, somniloquy is ground one's teeth in sleep, xerostomia, yellowish urine is hard and dry, the easy act of man's postcoital protrusion or sexual impotence, premature ejaculation, seminal emission, women's infrequent menstruation amenorrhea, or see metrorrhagia, emaciated physique, hectic fever night sweat, dysphoria with feverish sensation in the chest palms and soles, dry pharynx flushed cheeks, the yellow urine dry stool, red tongue with a little fluid, thready and rapid pulse.The kidney being the origin of congenital constitution, and cloudy essence in the kidney is total source of the cloudy liquid of the whole body.Deficiency of YIN-essence can cause various diseases, such as dizziness and tinnitus, and soreness of the waist and knees, osteopyrexia and fever, quench one's thirst (diabetes) etc.
Treat the symptom of suffering from a deficiency of the kidney, need to according to different symptom medical treatments, control take the kidney invigorating as main.Improve health, except strengthening physical exercise, also can take traditional Chinese patent medicine to nurse one's health, such as the Dihuang Wan series prescription of the kidney invigorating.Although yet the Dihuang Wan flavour of a drug are simple, effect is unstable.
Summary of the invention
In view of this, the object of the invention provides the Chinese medicine composition with resisting fatigue, kidney tonifying functions of a kind of definite effect, stable effect.
For realizing purpose of the present invention, the present invention adopts following technical scheme:
The Chinese medicine composition of a kind of resisting fatigue, kidney tonifying functions, made by following weight portion raw material:
70 ~ 80 parts of 90 ~ 110 parts of Fructus Lycii of 90 ~ 110 parts of Semen Cuscutae of Herba Cistanches
25 ~ 35 parts of 25 ~ 35 portions of Hippocampus of Radix Ginseng Rubra.
Chinese medicine composition of the present invention selects the Chinese medicine of the five flavours materials such as Herba Cistanches, Semen Cuscutae, Fructus Lycii, Radix Ginseng Rubra and Hippocampus to make.
Wherein, Herba Cistanches has another name called dried meat floss Rong, black commandant, is the fleshy stem of orobanchaceae plant cistanche or Herba Cistanches, fan's Herba Cistanches etc.Herba Cistanches sweet in the mouth, salty, warm in nature, return kidney channel, large intestine channel, have the effects such as kidney-replenishing, benefiting essence-blood, intestine moistening road, sexual impotence, seminal emission, nebulousurine, the frequent micturition heeltap, lumbago flaccidity of the lower limbs, the tinnitus order that is used for the treatment of kidney yang deficiency, asthenia of essence and blood spent, the diseases such as phase, infertility, dryness of the intestine constipation are spread out in menstruation.
Semen Cuscutae has another name called Herba cuscutae reality, SEMEN CUSCUTAE, imperial palpus, is the mature seed of convolvulus cuscuta plant.Semen Cuscutae acrid in the mouth, sweet, property is put down, return the liver,kidney,spleen warp, have the effects such as the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, solid tire stopping leak, be used for the treatment of soreness of waist and knee joint, seminal emission, sexual impotence, premature ejaculation, sterile, quench one's thirst, stranguria with turbid discharge, the enuresis, blurred vision tinnitus, frequent fetal movement, the disease such as miscarry, have loose bowels.
Fructus Lycii has another name called Fructus Lycii, Gou Qizi, sweet in the mouth, and property is flat, returns liver, kidney, lung meridian, has nourishing the liver, and the effects such as nourishing kidney, lung moistening are used for the treatment of caused by liver and kidney deficiency, have a dizzy spell, the diseases such as visual one clear, soreness of the waist and knees, the expensive essence of sexual impotence, cough due to consumptive disease, the taking fluids profusely of quenching one's thirst.
Radix Ginseng Rubra is the dry root of cultivation product (practise and claim Radix Ginseng Sativus) after steaming of Araliaceae Radix Ginseng PanaxginsengC.A.Mey..Radix Ginseng Rubra sweet in the mouth, little hardship, warm in nature, return spleen, lung, heart channel, have strongly invigorating primordial QI, answer the effects such as arteries and veins takes off admittedly, nourishing qi to stop, be used for the treatment of the diseases such as weak body and prostration, cold extremities faint pulse, QI failing to control blood, metrostaxis, heart failure, cardiogenic shock.
Hippocampus has another name called water horse, tilefiss, the dragon fish of beginning, and sweet in the mouth, salty is warm in nature, returns liver, kidney channel.Hippocampus has the effects such as kidney invigorating and YANG supporting, mass dissipating and swelling eliminating, is used for the treatment of the diseases such as impotence due to deficiency of the kidney, cold womb are infertile, the enuresis, dyspnea due to deficiency, lumps in the chest and abdomen, traumatic injury, carbuncle pyogenic infections from tumour or sore.
As preferably, Chinese medicine composition of the present invention, made by following weight portion raw material:
80 parts of 100 parts of Fructus Lycii of 100 parts of Semen Cuscutae of Herba Cistanches
0 part of 30 parts of hippocampus 3 of Radix Ginseng Rubra.
The present invention also provides the preparation method of described Chinese medicine composition, comprising:
Step 1: get 90 ~ 110 weight portion Herba Cistanches, 90 ~ 110 weight portion Semen Cuscutae and 70 ~ 80 weight portion Fructus Lycii and decoct with water rear filtration, filtrate is concentrated into the thick paste shape, is dried and crushed into fine powder for subsequent use;
Step 2: getting 25 ~ 35 weight portion Radix Ginseng Rubra and 25 ~ 35 weight portion Hippocampus, to be ground into fine powder for subsequent use;
Step 3: get sieve respectively rear mix homogeneously and get final product of step 1 gained fine powder and step 2 gained fine powder.
As preferably, the described extracting in water of preparation method step 1 of the present invention is that the decocting that adds 6-8 times of weight boils 2 ~ 3 times, each 1.5 ~ 2.5 hours, and merge extractive liquid.
As preferably, described the sieving of preparation method step 2 of the present invention is to cross 60 mesh sieves.
The present invention also provides the Chinese medicine composition of above-mentioned preparation method preparation.
The present invention also provides the clinical preparation of described Chinese medicine composition.Required various pharmaceutically conventional adjuvants when those skilled in the art can add the preparation different dosage form with Chinese medicine composition of the present invention according to different patients' demand, such as disintegrating agent, lubricant, emulsifying agent, binding agent etc., with conventional method of Chinese medicinal, make common dosage forms such as capsule, tablet, pill, granule, oral liquid etc. through the direct or indirect adding acceptable adjuvant pharmaceutically of routine processing.
Preferably, the clinical preparation of Chinese medicine composition of the present invention is capsule, and compliance is good, and is with strong points, is conducive to the patient and absorbs.
The invention provides a kind of capsule with resisting fatigue, kidney tonifying functions, with the described Chinese medicine composition of 340 weight portions and 10 weight portion starch mixings, add ethanol and do the wetting agent granulation, fill out capsule, and get final product.
The present invention is through clinical observation on the therapeutic effect, suffer from a deficiency of the kidney in 120 examples, in the fatiguability user, after taking continuously 15 days with Chinese medicinal composition capsules agent of the present invention, 103 examples that obviously spirit takes a turn for the better, the situation of suffering from a deficiency of the kidney is greatly improved, 15 examples that spirit takes a turn for the better, the situation of suffering from a deficiency of the kidney alleviates to some extent, total effective rate is 98.3%, invalid 2 examples, and inefficiency accounts for 1.7%.
The invention provides the Chinese medicine composition with resisting fatigue, kidney tonifying functions of a kind of determined curative effect, stable effect, modern pharmacology research and clinical trial show, Chinese medicine composition of the present invention has the effect of the kidney invigorating and essence nourishing, nourishing liver and replenishing blood, the kidney invigorating effect is remarkable, do not rebound, having no side effect, is the good recipe of resisting fatigue and treatment deficiency of the kidney, can be widely used in because the clinical treatment of the diseases such as the fatiguability that causes of suffering from a deficiency of the kidney, the vertigo, impotence and premature ejaculation, infertility.
The specific embodiment
The embodiment of the invention discloses a kind of have resisting fatigue, kidney tonifying functions Chinese medicine composition and preparation method thereof.Those skilled in the art can use for reference this paper content, suitably improve technological parameter and realize.Special needs to be pointed out is, all similarly replace and change apparent to those skilled in the art, and they all are deemed to be included in the present invention.Product of the present invention and method are described by preferred embodiment, the related personnel obviously can be within not breaking away from content of the present invention, spirit and scope to product as herein described with method is changed or suitably change and combination, realize and use the technology of the present invention.
In order further to understand the present invention, the present invention is described in detail below in conjunction with embodiment.
Embodiment 1: the Chinese medicine composition with kidney tonifying functions of the present invention
Described Chinese medicine composition is to be made by the crude drug of following weight:
Herba Cistanches 90g Semen Cuscutae 110g Fructus Lycii 70g
Radix Ginseng Rubra 35g Hippocampus 25g
Preparation method is that the decocting of getting the Herba Cistanches of described weight, Semen Cuscutae, 6 times of weight of Fructus Lycii adding boils 2 times, each 2 hours, merge extractive liquid, filtered, filtrate is concentrated into the thick paste shape, crosses 60 mesh sieve mix homogeneously after pulverizing with Radix Ginseng Rubra, Hippocampus after the dried filtrate and get final product.
Embodiment 2: the Chinese medicine composition with kidney tonifying functions of the present invention
Described Chinese medicine composition is to be made by the crude drug of following weight:
Herba Cistanches 110g Semen Cuscutae 90g Fructus Lycii 80g
Radix Ginseng Rubra 25g hippocampus 3 5g
Preparation method is that the decocting of getting the Herba Cistanches of described weight, Semen Cuscutae, 8 times of weight of Fructus Lycii adding boils 2 times, and each 2.5 hours, merge extractive liquid, filtered, and filtrate is concentrated into the thick paste shape, is dried and crushed into fine powder for subsequent use; What other got described weight is ground into fine powder with Radix Ginseng Rubra, Hippocampus, crosses respectively behind 60 mesh sieves mix homogeneously with the fine powder of gained before and get final product.
Embodiment 3: the Chinese medicine composition with kidney tonifying functions of the present invention
Described Chinese medicine composition is to be made by the crude drug of following weight:
Herba Cistanches 100g Semen Cuscutae 100g Fructus Lycii 80g
Radix Ginseng Rubra 30g hippocampus 3 0g
Preparation method is that the decocting of getting the Herba Cistanches of described weight, Semen Cuscutae, 6 times of weight of Fructus Lycii adding boils 3 times, and each 1.5 hours, merge extractive liquid, filtered, and filtrate is concentrated into the thick paste shape, is dried and crushed into fine powder for subsequent use; What other got described weight is ground into fine powder with Radix Ginseng Rubra, Hippocampus, crosses respectively behind 60 mesh sieves mix homogeneously with the fine powder of gained before and get final product.
Embodiment 4: the capsule with kidney tonifying functions of the present invention
Crude drug by following weight is made:
Herba Cistanches 100g Semen Cuscutae 100g Fructus Lycii 80g
Radix Ginseng Rubra 30g hippocampus 3 0g
Preparation method is that the decocting of getting the Herba Cistanches of described weight, Semen Cuscutae, 6 times of weight of Fructus Lycii adding boils 2 times, and each 2 hours, merge extractive liquid, filtered, and it is for subsequent use that filtrate is dried and crushed into fine powder; What other got described weight is ground into fine powder with Radix Ginseng Rubra, Hippocampus, crosses respectively mix homogeneously behind 60 mesh sieves with the fine powder of gained before, adds 10g starch and does the wetting agent granulation with ethanol, and drying incapsulates and get final product.
Embodiment 5: the effect observation of Chinese medicine composition of the present invention
Observe the effect of using Chinese medicine composition the kidney invigorating of the present invention.
240 routine Patients with Kidney Deficiency Types are divided into experimental group and matched group at random, and every group of 120 examples are taken respectively Chinese medicine composition and the commercially available Dihuang Wan series prescription of embodiment 3 preparations.
Diagnostic criteria: with reference to clinical criteria, and light with the symptom calibration, in, severe.
Therapeutic Method: test group is taken Chinese medicine composition of the present invention, and matched group uses Dihuang Wan series prescription, and equal every day three times, 5 days is a course for the treatment of, treats altogether 3 courses for the treatment of.Stop other western medicines in treatment during the treatment.
Observation of curative effect: the present invention has obtained preferably curative effect clinically, suffer from a deficiency of the kidney in 120 examples, in the fatiguability user, after taking continuously 15 days with Chinese medicinal composition capsules agent of the present invention, 103 examples that obviously spirit takes a turn for the better, the situation of suffering from a deficiency of the kidney is greatly improved, spirit takes a turn for the better, 15 examples that the situation of suffering from a deficiency of the kidney alleviates to some extent, and total effective rate is 98.3%, invalid 2 examples, inefficiency accounts for 1.7%.The matched group effective percentage is that 57.2%, two group of cure rate relatively has significant difference (P＜0.05).
The explanation of above embodiment just is used for helping to understand method of the present invention and core concept thereof.Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention, can also carry out some improvement and modification to the present invention, these improvement and modification also fall in the protection domain of claim of the present invention.
Claims (9)
1. the Chinese medicine composition with resisting fatigue, kidney tonifying functions is characterized in that, is made by following weight portion raw material:
70 ~ 80 parts of 90 ~ 110 parts of Fructus Lycii of 90 ~ 110 parts of Semen Cuscutae of Herba Cistanches
25 ~ 35 parts of 25 ~ 35 portions of Hippocampus of Radix Ginseng Rubra.
2. Chinese medicine composition according to claim 1 is characterized in that, is made by following weight portion raw material:
80 parts of 100 parts of Fructus Lycii of 100 parts of Semen Cuscutae of Herba Cistanches
0 part of 30 parts of hippocampus 3 of Radix Ginseng Rubra.
3. the preparation method with Chinese medicine composition of resisting fatigue, kidney tonifying functions is characterized in that, comprising:
Step 1: get 90 ~ 110 weight portion Herba Cistanches, 90 ~ 110 weight portion Semen Cuscutae and 70 ~ 80 weight portion Fructus Lycii and decoct with water rear filtration, filtrate is concentrated into the thick paste shape, is dried and crushed into fine powder for subsequent use;
Step 2: getting 25 ~ 35 weight portion Radix Ginseng Rubra and 25 ~ 35 weight portion Hippocampus, to be ground into fine powder for subsequent use;
Step 3: get sieve respectively rear mix homogeneously and get final product of step 1 gained fine powder and step 2 gained fine powder.
4. described preparation method according to claim 3 is characterized in that, step 1 is described to be decocted with water as the decocting that adds 6-8 times of weight boils 2 ~ 3 times, each 1.5 ~ 2.5 hours, and merge extractive liquid.
5. described preparation method according to claim 3 is characterized in that, described the sieving of step 2 is to cross 60 mesh sieves.
6. the Chinese medicine composition of the described preparation method of any one preparation according to claim 3-5.
7. the clinical preparation that comprises claim 1,2 or 6 described Chinese medicine compositions.
8. described clinical preparation according to claim 7 is characterized in that, it is capsule.
9. the capsule with resisting fatigue, kidney tonifying functions is characterized in that, with 340 weight portion claim 1,2 or 8 described Chinese medicine compositions and 10 weight portion starch mixings, adds ethanol and does the wetting agent granulation, fills out capsule, and get final product.
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| CN2012103879030A CN102872267A (en) | 2012-10-12 | 2012-10-12 | Traditional Chinese medicine composition for resisting fatigue and tonifying kidney, and preparation method thereof |
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| CN1562337A (en) * | 2004-03-17 | 2005-01-12 | 沈阳市东陵药物研究所 | Chinese traditional medicine for treating insufficiency of kidney-yang and preparaton method |
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Application publication date: 20130116 |