CN102861314A - Medicine for treating nephropathy and preparation method thereof - Google Patents
Medicine for treating nephropathy and preparation method thereof Download PDFInfo
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- CN102861314A CN102861314A CN2012104166187A CN201210416618A CN102861314A CN 102861314 A CN102861314 A CN 102861314A CN 2012104166187 A CN2012104166187 A CN 2012104166187A CN 201210416618 A CN201210416618 A CN 201210416618A CN 102861314 A CN102861314 A CN 102861314A
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Abstract
The invention discloses a medicine for treating nephropathy and a preparation method of the medicine. The medicine is mainly prepared by pericarpium citri reticulatae, rhizoma alismatis, cassia twig, pyrrosia lingua, leonurus, Chinese date, immature bitter orange, mangnolia officinalis, manchurian wild ginger, plantain seed, liquorice and poria cocos based on a certain weight ratio. The medicine disclosed by the invention has the functions on tonifying spleen, tonifying lung and reinforcing kidney, has quick effect on treatment of nephropathy, is short in treatment course, has no recurrence and has high recovery rate.
Description
Technical field
The present invention relates to a kind of medicine for the treatment of nephropathy and preparation method thereof, belong to the field of Chinese medicines.
Background technology
Nephropathy, the various diseases of kidney.Between the viscera, all keep dynamic equilibrium between interior environment and the external environment.If the multiple paathogenic factor in the interior external world has been destroyed the balance of human body, cause internal organs QI and blood functional disorder, sick reaching in kidney causes that kidney disease produces.The traditional Chinese medical science is thought the kidney generating marrow and dominating bone, the same brain of marrow, good renal function is very large with bad relation with bone marrow, when suffering from a deficiency of the kidney, can affect the absorption of trace element, cause the shortage of trace element, and the shortage of trace element can further cause and suffer from a deficiency of the kidney, and enters a vicious cycle, and Here it is suffers from a deficiency of the kidney and cause the reason of various diseases.Western medicine can't effectively be treated nephropathy at present, and doctor trained in Western medicine often adopts the medicines such as oral hormone, Radix Tripterygii Wilfordii, cyclophosphamide to control urine protein, occult blood.Just the begin treatment effect is also obvious, but run into flu, fatigue shows effect again.So repeatedly, increase the weight of time by time, gradually occur to feel sick, the renal insufficiency symptom such as vomiting, the one, cause the waste of patient's fund, second cause the touching difficulty of disease more, Relapse rate.Therefore, there is great demand in people to the Chinese medicine of effective treatment nephropathy.
Summary of the invention
The inventor has finally found the medicine of effective treatment nephropathy, thereby has finished the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.
Purpose of the present invention just provides a kind of composition of medicine that can treat nephropathy.
Another object of the present invention has just provided the preparation method of this composition of medicine.
Medicine of the present invention selects Pericarpium Citri Reticulatae, Rhizoma Alismatis, Ramulus Cinnamomi, Folium Pyrrosiae, Herba Leonuri, Fructus Jujubae, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Herba Asari, Semen Plantaginis, Radix Glycyrrhizae, Poria, the Radix Aucklandiae, Polyporus, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis Recens, Radix Platycodonis, Fructus Foeniculi, the Rhizoma Pinelliae, Radix Ginseng, Rhizoma Coptidis, the Radix Astragali, Rhizoma Dioscoreae, Cortex Moutan, Radix Achyranthis Bidentatae, Rhizoma Chuanxiong, Cortex Mori, Radix Paeoniae Alba to make up, with these drug regimens so that each efficacy of drugs produces synergism, thereby recurrence that can the fast treating nephropathy.Wherein select Pericarpium Citri Reticulatae to be because its nature and flavor are bitter, hot, temperature is returned lung, spleen channel, and regulating qi-flowing for strengthening spleen is arranged, and the function of drying dampness to eliminate phlegm is controlled fullness in the epigastrium and chest, lack of appetite and vomiting, cough with copious phlegm.Select Rhizoma Alismatis to be because its nature and flavor are sweet, cold, enter urinary bladder channel, diuretic is arranged, eliminating dampness by diuresis, the function that expels the heat-evil is controlled dysuria, and the edema anus is full, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.Selecting Ramulus Cinnamomi is that temperature enters bladder, the heart, lung meridian, and the diaphoresis expelling pathogenic factors from muscles is arranged because of its property acrid-sweet flavor, and the function of warming the meridian and promoting blood circulation is controlled exterior syndrome due to wind-cold, shoulder back of the body podomere ache, thoracic obstruction phlegm retention, amenorrhea and mass in the abdomen.Selecting Folium Pyrrosiae is that cold enters lung, urinary bladder channel, and relieving stranguria by diuresis is arranged because of its property bitter but sweet flavor, and the function that lung heat clearing expels the heat-evil is controlled and drenched pain, hematuria, lithangiuria, nephritis, metrorrhagia, dysentery, cough due to lung-heat, chronic tracheitis, incised wound, carbuncle.Select Herba Leonuri to be because its nature and flavor are arduous, cold enters pericardium, Liver Channel, invigorate blood circulation, and blood stasis dispelling, regulating menstruation, the function of the water that disappears is controlled menoxenia, controls Lou difficult labour, retention of placenta, puerperal blood faints, abdominal pain due to blood stasis, metrorrhagia and metrostaxis, hematuria is rushed down blood, the carbuncle skin infection.Select Fructus Jujubae to be because its nature and flavor are sweet, temperature enters spleen, stomach warp, and the spleen reinforcing stomach function regulating is arranged, and supplementing QI for promoting the production of body fluid transfers battalion to defend, and separates the function of poison of drug, controls the insufficiency of stomach lack of appetite, the weak loose stool of spleen, and qi-blood-body fluid is not enough, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.Select Fructus Aurantii Immaturus to be because its nature and flavor are bitter, cold, enter spleen, stomach warp, dispelling the stagnated QI is arranged, loose painful abdominal mass is rushed down expectorant, and the function of removing food stagnancy is controlled chest and abdomen swelling and pain, the thoracic obstruction, painful abdominal mass pain, accumulation of phlegm in the hypochondrium, edema, food stagnation, constipation, gastroptosis, uterine prolapse, proctoptosis.Selecting Cortex Magnoliae Officinalis is that temperature enters spleen, stomach, large intestine channel, and warming middle-JIAO is arranged because of its nature and flavor toil, the therapeutic method to keep the adverse QI flowing downwards, and dampness, the function of expectorant is controlled breast abdomen feeling of fullness distending pain, regurgitation, vomiting, dyspepsia does not disappear, and phlegm retention is breathed with cough, the cold-damp dysentery.Select Herba Asari to be because its nature and flavor are hot, temperature enters lung, kidney channel, dispel the wind, and cold expelling, row water is opened the function of stealing, and controls air-cooled headache, nasal sinusitis, pain relieving, phlegm retention cough with dyspnea, rheumatic arthralgia.Select Semen Plantaginis to be because its nature and flavor are sweet, cold, enter kidney, urinary bladder channel, diuretic is arranged, heat clearing away makes eye bright, and the function of eliminating the phlegm is controlled urinary obstruction, stranguria with turbid discharge, leukorrhagia, hematuria, the heat-damp in summer dysentery, cough ant phlegm, arthralgia chiefly caused by damp pathogen, conjunctival congestion is hidden from view.Select Radix Glycyrrhizae to be because its nature and flavor are sweet flat, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, detoxifcation, the function of coordinating the actions of various ingredients in a prescription, process with controlling weakness of the spleen and stomach, lack of appetite, stomachache loose stool, the overstrain heating, consumptive lung disease cough, cardiopalmus, frightened carbuncle is given birth to controlling laryngopharynx swelling and pain, peptic ulcer, ulcer sores is separated poison of drug and alimentary toxicosis.Select Poria to be because its property slightly sweet flavor is flat, enter the heart, spleen, lung meridian, eliminating dampness and diuresis is arranged, the strengthening the spleen stomach function regulating, the function of mind tranquilizing and the heart calming is controlled dysuria, the edema distension, the phlegm retention cough with dyspnea, the sound of vomiting of vomitting is had loose bowels, seminal emission, stranguria with turbid discharge, palpitation with fear, forgetful.Select the Radix Aucklandiae to be because its nature and flavor are arduous, temperature enters lung, liver, spleen channel, and promoting the circulation of QI to relieve pain are arranged, and the function of warming middle-JIAO for easing the stomach is controlled the invasion by pathogenic cold stagnation of QI, chest and abdomen swelling and pain, and dysentery tenesmus, colic of cold type are had loose bowels in vomiting.Select Polyporus to be because its property slightly sweet flavor is flat, enter spleen, kidney, urinary bladder channel, the function of diuresis eliminating dampness by diuresis is arranged, control dysuria, the edema distension, beriberi is had loose bowels, pouring, turbid, leukorrhagia.Selecting the Rhizoma Atractylodis Macrocephalae is because its property bitter but sweet flavor, and temperature enters spleen, stomach warp, and spleen reinforcing is arranged, stomach reinforcing, dampness, and in function, control deficient QI of the spleen and stomach, anorexia, the asthenia weak breath, deficiency-distension is had loose bowels, phlegm retention, edema, jaundice, arthralgia chiefly caused by damp pathogen, dysuria, dizziness, spontaneous perspiration, nausea is uneasy.Select Rhizoma Zingiberis Recens to be because its nature and flavor are hot, temperature enters lung, stomach, spleen channel, deliver, and cold expelling, preventing or arresting vomiting is opened the function of expectorant, the wind and cold that cures cold, vomiting, phlegm retention is breathed with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poisoning.Select Radix Platycodonis to be because its nature and flavor toil is flat, enter lung, stomach warp, lung qi dispersing gas is arranged out, the function of the evacuation of pus of eliminating the phlegm is controlled the exogenous cough, laryngopharynx swelling and pain, lung abscess vomiting pus, fullness in the chest and hypochondriac pain, dysentery stomachache.Select Fructus Foeniculi to be because its nature and flavor are hot, temperature is returned liver,kidney,spleen, stomach warp, and dispersing cold for relieving pain is arranged, and the function of regulating qi-flowing for harmonizing stomach is controlled colic of cold type stomachache, the testis swelling and hanging down of either of the testes, dysmenorrhea, few abdomen cold type of pain, distension and fullness in the abdomen, lack of appetite and vomiting, hydrocele of testis.Select the Rhizoma Pinelliae to be because its nature and flavor are hot, temperature, poisonous, enter spleen, stomach warp, drying dampness to eliminate phlegm is arranged, stopping nausea and vomiting by lowering the adverse flow of QI, the function of dissolving lump and resolving mass is controlled the damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm headache, dizzy sleeplessness, outer subduing inflammation.Select Radix Ginseng to be because its nature and flavor are sweet little sweet, temperature enters spleen, lung meridian, and strongly invigorating primordial QI is arranged, promote the production of body fluid admittedly take off, the function of calming the nerves, it is deficient to control impairment caused by overstrain, lack of appetite, asthenia, food is told in regurgitation, the stool lingering diarrhea, empty cough with asthma is short, the spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition is quenched one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency are not multiple, the disease of all qi-blood-body fluid deficiencies.Select Rhizoma Coptidis to be because its nature and flavor are bitter, cold, enter the heart, liver, stomach, large intestine channel, pathogenic fire purging is arranged, dampness, detoxifcation, the function of parasite killing, row pyretic toxicity, typhoid fever when controlling, intenseness of heat is vexed, feeling of fullness vomiting, bacillary dysentery, diarrhea of heat type stomachache, pulmonary tuberculosis is told, nosebleed, hematochezia, quenches one's thirst infantile malnutrition, ascariasis, pertussis, laryngopharynx swelling and pain, acute catarrhal conjunctivitis, aphtha, skin sore, eczema, the burning hot wound of soup.Select the Radix Astragali to be because its nature and flavor are sweet, tepor enters lung, spleen channel, give birth to the useful consolidating superficial resistance of defending, and inducing diuresis to remove edema, poison holding, the function of granulation promoting is controlled spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle are not burst or are burst and hold back for a long time; Process with the function that the invigorating middle warmer benefit is arranged, control the internal injury overstrain, diarrhea due to hypofunction of the spleen, proctoptosis, deficiency of vital energy blood prostration, the disease of metrorrhagia and leukorrhagia and all weakness of QI blood deficiency.Select Rhizoma Dioscoreae to be because its nature and flavor are sweet, flat, enter lung, spleen, kidney channel, spleen invigorating is arranged, tonifying the lung is reinforced the kidney, and the function that benefit is smart is controlled diarrhea due to hypofunction of the spleen, chronic dysentery, cough due to consumptive disease is quenched one's thirst, seminal emission, leukorrhagia, frequent micturition.Select Cortex Moutan to be because its nature and flavor are arduous, cold enters the heart, liver, kidney channel, and heat clearing away is arranged, removing heat from blood, and blood, and the function of repercussive is controlled the pathogenic heat attacking blood system in febrile diseases, sends out speckle ， Jing Epilepsy, and tell, be defeated in battle, have blood in stool, the hectic fever due to YIN-deficiency consumptive fever, amenorrhea ， mass in the abdomen, carbuncle and ulcer is pounced on damage.Select Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid is flat, enter liver, kidney channel, give birth to and use dissipating blood stasis blood, subduing inflammation is controlled gonorrhea, hematuria, amenorrhea ， mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury is ripely used invigorating the liver and kidney, and bone and muscle strengthening is controlled waist kneecap pain, four fertile contractures, flaccidity syndrome and arthralgia syndrome.Select Rhizoma Chuanxiong to be because its nature and flavor are hot, temperature enters liver, gallbladder meridian, and activating QI to alleviate the depression is arranged, dispeiling pathogenic wind and removing dampness, and the function of promoting blood circulation and stopping pain is controlled air-cooled headache and is revolved dizzyly, and the hypochondriac pain abdomen is painful, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation piece pain, ulcer sores.Select Cortex Mori to be because its nature and flavor are sweet, cold, enter lung, spleen channel, eliminating pathogen from the lung for relieving asthma is arranged, the function of line water detumescence is controlled dyspnea and cough due to lung-heat, spits blood edema, beriberi, dysuria.Selecting Radix Paeoniae Alba is that cold enters liver, spleen channel, and nourishing blood to suppress the hyperactive liver is arranged because of its nature and flavor picric acid, slow middle pain relieving, and yin fluid astringing is received the function of antiperspirant, controls the breast abdomen pain over the hypochondriac region, dysentery stomachache, spontaneous sweating, fever due to yin deficiency, menoxenia, metrorrhagia, leukorrhagia.
The specific embodiment
The drug dose of component of the present invention also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has good therapeutic effect in the following weight scope
Pericarpium Citri Reticulatae 10-25 gram Rhizoma Alismatis 10-20 gram Ramulus Cinnamomi 6-12 gram
Folium Pyrrosiae 10-20 gram Herba Leonuri 10-30 gram Fructus Jujubae 10-20 gram
Fructus Aurantii Immaturus 10-25 gram Cortex Magnoliae Officinalis 10-22 gram Herba Asari 10-25 gram
Semen Plantaginis 8-18 gram Radix Glycyrrhizae 5-15 gram Poria 10-20 gram
Radix Aucklandiae 10-22 gram Polyporus 10-25 gram Rhizoma Atractylodis Macrocephalae 10-20 gram
Rhizoma Zingiberis Recens 4-8 gram Radix Platycodonis 13-20 gram Fructus Foeniculi 6-12 gram
Rhizoma Pinelliae 10-20 gram Radix Ginseng 10-14 gram Rhizoma Coptidis 4-14 gram
Radix Astragali 10-15 Keshan medicine 10-20 gram Cortex Moutan 10-20 gram
Radix Achyranthis Bidentatae 8-18 gram Rhizoma Chuanxiong 10-18 gram Cortex Mori 10-20 gram
Radix Paeoniae Alba 10-14 gram
Wherein, be preferably
Pericarpium Citri Reticulatae 10 gram Rhizoma Alismatis 15 gram Ramulus Cinnamomi 8 grams
Folium Pyrrosiae 12 gram Herba Leonuris 20 gram Fructus Jujubaes 12 grams
Fructus Aurantii Immaturus 18 gram Cortex Magnoliae Officinalis 14 gram Herba Asaris 15 grams
Semen Plantaginis 10 gram Radix Glycyrrhizaes 8 gram Poria 15 grams
The Radix Aucklandiae 13 gram Polyporus 15 gram Rhizoma Atractylodis Macrocephalaes 13 grams
Rhizoma Zingiberis Recens 6 gram Radix Platycodoniss 15 gram Fructus Foeniculi 8 grams
The Rhizoma Pinelliae 15 gram Radix Ginsengs 12 gram Rhizoma Coptidis 6 grams
The Radix Astragali 12 Keshan medicines 13 gram Cortex Moutans 13 grams
Radix Achyranthis Bidentatae 15 gram Rhizoma Chuanxiongs 12 gram Cortex Mori 12 grams
Radix Paeoniae Alba 12 grams
The preparation method of medicine of the present invention is as follows
One, gets the raw materials ready
1, Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, moistens softly, and shredding is dried or cold drying, sieve dedust bits;
2, Rhizoma Alismatis: choose decontamination, big or small stepping is soaked in water to eighty per cant saturating, pulls out, shines coolly, and moistening is even to inside and outside humidity, and section is dried;
3, Ramulus Cinnamomi: water slightly soaks, and pulls out, and moistening is cut into slices to thoroughly, dries, and sieves anti-dandruff;
4, Folium Pyrrosiae: choose clean impurity, the flush away silt particle, the outwash fine hair, cutting is dried;
5, Herba Leonuri: choose decontamination, clean, run through, cutting is dried;
6, Fructus Jujubae: choose clean impurity, dry;
7, Fructus Aurantii Immaturus: choose clean impurity, be soaked in water to eighty per cant saturating, pull out, profit is to interior without hard-core, and section is dried;
8, Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding is dried;
9, Herba Asari: Ex-all impurity, water spray profit, in time cutting is dried;
10, Semen Plantaginis: choose decontamination, sieve removes spare, empty grain;
11, Radix Glycyrrhizae: choose decontamination, clean, be soaked in water to eighty per cant thoroughly the time, pull out, run through section, airing;
12, Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;
13, the Radix Aucklandiae: crude drug in whole put in the clear water clean, pull out, moistening made soft in 12-24 hours, and section is dried;
14, Polyporus: clean silt particle, moisten soft section, dry;
15, the Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out behind the bubble, run through, section is dried;
16, Rhizoma Zingiberis Recens: choose decontamination, clean earth, the time spent section;
17, Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through rear section, dry;
18, Fructus Foeniculi: get crude drug, remove impurity;
19, the Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
20, Radix Ginseng: except removing LU, cutting;
21, Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section is dried in the shade;
22, the Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;
23, Rhizoma Dioscoreae: choose clean impurity, be soaked in water and pull out and slightly dry in the air for degree to the Rhizoma Dioscoreae central part is softening, section is dried or is dried;
24, Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried;
25, Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;
26, Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices drying behind the moistening;
27, Cortex Mori: brush away the ash bits, clean, run through rear shredding, dry;
28, Radix Paeoniae Alba: choose decontamination, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying.
Two, preparation
1, Pericarpium Citri Reticulatae, Rhizoma Alismatis, Ramulus Cinnamomi, Folium Pyrrosiae, Herba Leonuri, Fructus Jujubae, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Herba Asari, Semen Plantaginis, Radix Glycyrrhizae, Poria, the Radix Aucklandiae, Polyporus, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis Recens, Radix Platycodonis, Fructus Foeniculi, the Rhizoma Pinelliae, Radix Ginseng, Rhizoma Coptidis, the Radix Astragali, Rhizoma Dioscoreae, Cortex Moutan, Radix Achyranthis Bidentatae, Rhizoma Chuanxiong, Cortex Mori, the Radix Paeoniae Alba with described weight adds 6 times of water gagings, intense fire decocts boiling 20 minutes, used again slow fire boiling 20 minutes, filter, get for the first time decoction liquor.
2, the medicinal residues that filter are added 3 times of amounts of water, intense fire decocts, and simmers in water 20 minutes again, filters, and gets for the second time decoction liquor.
3, decoct medicinal liquid with twice and merge, mix homogeneously, intense fire boils, and uses slow fire boiling 10 minutes again, must take medicinal liquid, and medicinal liquid is divided into 4 doses.
Medicine of the present invention has spleen invigorating, tonifying the lung, and the function of reinforcing the kidney, treatment nephropathy instant effect, short treating period does not recur, and cure rate is high.
Below further set forth the beneficial effect of medicine of the present invention by test example, these tests comprise animal toxicity test and the clinical observation test of medicine of the present invention.
The animal toxicity test report of [test example 1] medicine of the present invention:
Get 20 of rabbit, the male and female dual-purpose, body weight 2.3-2.5kg divides two groups, and 10 every group, wherein one group is the overdose test group, and another group is the normal amount test group.The super quantity group is 25ml/kg, and normal amount is 10ml/kg, and administering mode is the administration by gavage administration, once a day, serve on 7 days, observes the administration reaction every day, and the result shows that two groups of rabbit are movable, diet is normal, and medicine is without bad toxic and side effects.
The clinical observation material of [test example 2] medicine of the present invention
1, physical data
Accept out-patient's 300 examples for medical treatment.
2, diagnostic criteria
Renal colic: pain breaks out, and often to the radiation of the positions such as lower abdomen, pudendum and femoribus internus, is intermittent violent angor.Often by due to calculus, clot or the slough obstruction in the ureter.
Kidney district dull pain and distending pain: the pain over renal region due to the diseases of urinary system comprises: 1. the kidney enlargement is led support kidney tunicle and is caused, such as acute nephritis, acute pyelonephritis, hydronephrosis, polycystic kidney, renal carcinoma, nephroptosis etc.2. disease is lumbago caused kidney week: such as perinephric abscess, the concurrent perinephritis of renal infarction, cyst of kidney is broken and perirenal hematoma etc.But many lumbagos are to cause that by spinal column and the other soft tissue diseases of spinal column pancreas, gallbladder, stomach pain also often emit to waist.
3, Therapeutic Method
Select above-mentioned medicament, each serving with 1 dose, every day early, middle and late respectively taking 1 time.14 days is a course for the treatment of, takes continuously 4 courses for the treatment of.
4, efficacy assessment standard
Produce effects: clinical symptom disappearance after the treatment, the nephropathy recovery from illness is observed half a year without the recidivist;
Take a turn for the better: clinical symptoms is obviously improved, and nephropathy is progressively recovered;
Invalid: clinical partial symptoms disappears or without change, does not reach improvement standard person.
5, therapeutic outcome
In above-mentioned treatment, with Drug therapy nephrotic's 300 examples of the present invention, produce effects 280 examples as a result, obvious effective rate is 93.33%, 12 examples that take a turn for the better, improvement rate is 5.33%, invalid 8 examples, total effective rate is 97.33%.
Claims (3)
1. medicine for the treatment of nephropathy, it is characterized in that: it is to be made by the crude drug in the following weight scope:
Pericarpium Citri Reticulatae 10-25 gram Rhizoma Alismatis 10-20 gram Ramulus Cinnamomi 6-12 gram
Folium Pyrrosiae 10-20 gram Herba Leonuri 10-30 gram Fructus Jujubae 10-20 gram
Fructus Aurantii Immaturus 10-25 gram Cortex Magnoliae Officinalis 10-22 gram Herba Asari 10-25 gram
Semen Plantaginis 8-18 gram Radix Glycyrrhizae 5-15 gram Poria 10-20 gram
Radix Aucklandiae 10-22 gram Polyporus 10-25 gram Rhizoma Atractylodis Macrocephalae 10-20 gram
Rhizoma Zingiberis Recens 4-8 gram Radix Platycodonis 13-20 gram Fructus Foeniculi 6-12 gram
Rhizoma Pinelliae 10-20 gram Radix Ginseng 10-14 gram Rhizoma Coptidis 4-14 gram
Radix Astragali 10-15 Keshan medicine 10-20 gram Cortex Moutan 10-20 gram
Radix Achyranthis Bidentatae 8-18 gram Rhizoma Chuanxiong 10-18 gram Cortex Mori 10-20 gram
Radix Paeoniae Alba 10-14 gram.
2. medicine according to claim 1, wherein the consumption of each crude drug is:
Pericarpium Citri Reticulatae 10 gram Rhizoma Alismatis 15 gram Ramulus Cinnamomi 8 grams
Folium Pyrrosiae 12 gram Herba Leonuris 20 gram Fructus Jujubaes 12 grams
Fructus Aurantii Immaturus 18 gram Cortex Magnoliae Officinalis 14 gram Herba Asaris 15 grams
Semen Plantaginis 10 gram Radix Glycyrrhizaes 8 gram Poria 15 grams
The Radix Aucklandiae 13 gram Polyporus 15 gram Rhizoma Atractylodis Macrocephalaes 13 grams
Rhizoma Zingiberis Recens 6 gram Radix Platycodoniss 15 gram Fructus Foeniculi 8 grams
The Rhizoma Pinelliae 15 gram Radix Ginsengs 12 gram Rhizoma Coptidis 6 grams
The Radix Astragali 12 Keshan medicines 13 gram Cortex Moutans 13 grams
Radix Achyranthis Bidentatae 15 gram Rhizoma Chuanxiongs 12 gram Cortex Mori 12 grams
Radix Paeoniae Alba 12 grams.
3. the preparation method of described medicine according to claim 1 and 2, it is characterized in that: it comprises the following steps:
(1) gets the raw materials ready
(1) Pericarpium Citri Reticulatae: get crude drug, remove the peel of impurity and blackening, wash quickly is clean, moistens softly, and shredding is dried or cold drying, sieve dedust bits;
(2) Rhizoma Alismatis: choose decontamination, big or small stepping is soaked in water to eighty per cant saturating, pulls out, shines coolly, and moistening is even to inside and outside humidity, and section is dried;
(3) Ramulus Cinnamomi: water slightly soaks, and pulls out, and moistening is cut into slices to thoroughly, dries, and sieves anti-dandruff;
(4) Folium Pyrrosiae: choose clean impurity, the flush away silt particle, the outwash fine hair, cutting is dried;
(5) Herba Leonuri: choose decontamination, clean, run through, cutting is dried;
(6) Fructus Jujubae: choose clean impurity, dry;
(7) Fructus Aurantii Immaturus: choose clean impurity, be soaked in water to eighty per cant saturating, pull out, profit is to interior without hard-core, and section is dried;
(8) Cortex Magnoliae Officinalis: be soaked in water and pull out, scrape off rough bark after running through, clean, shredding is dried;
(9) Herba Asari: Ex-all impurity, water spray profit, in time cutting is dried;
(10) Semen Plantaginis: choose decontamination, sieve removes spare, empty grain;
(11) Radix Glycyrrhizae: choose decontamination, clean, be soaked in water to eighty per cant thoroughly the time, pull out, run through section, airing;
(12) Poria: be soaked in water, clean and to pull out, vexed after, cut into slices, dry;
(13) Radix Aucklandiae: crude drug in whole put in the clear water clean, pull out, moistening made soft in 12-24 hours, and section is dried;
(14) Polyporus: clean silt particle, moisten soft section, dry;
(15) Rhizoma Atractylodis Macrocephalae: choose clean impurity, be soaked in water, pull out behind the bubble, run through, section is dried;
(16) Rhizoma Zingiberis Recens: choose decontamination, clean earth, the time spent section;
(17) Radix Platycodonis: choose clean impurity, except removing LU, clean and pull out, run through rear section, dry;
(18) Fructus Foeniculi: get crude drug, remove impurity;
(19) Rhizoma Pinelliae: choose decontamination, sieve dedust bits;
(20) Radix Ginseng: except removing LU, cutting;
(21) Rhizoma Coptidis: choose decontamination, clean silt particle, run through, section is dried in the shade;
(22) Radix Astragali: choose clean impurity, remove residual root head and hollow the greater, be soaked in water, pull out, run through rear timely section, dry;
(23) Rhizoma Dioscoreae: choose clean impurity, be soaked in water and pull out and slightly dry in the air for degree to the Rhizoma Dioscoreae central part is softening, section is dried or is dried;
(24) Cortex Moutan: choose decontamination, remove core, clean, run through, section is dried;
(25) Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;
(26) Rhizoma Chuanxiong: choose decontamination, separate large and small, be soaked in water, solarization is dried in the air, and cuts into slices drying behind the moistening;
(27) Cortex Mori: brush away the ash bits, clean, run through rear shredding, dry;
(28) Radix Paeoniae Alba: choose decontamination, size separately is soaked in water to eighty per cant saturating, pulls out, and solarization is dried in the air, and profit is even to inside and outside humidity, section, drying;
(2) preparation
(1) Pericarpium Citri Reticulatae, Rhizoma Alismatis, Ramulus Cinnamomi, Folium Pyrrosiae, Herba Leonuri, Fructus Jujubae, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Herba Asari, Semen Plantaginis, Radix Glycyrrhizae, Poria, the Radix Aucklandiae, Polyporus, the Rhizoma Atractylodis Macrocephalae, Rhizoma Zingiberis Recens, Radix Platycodonis, Fructus Foeniculi, the Rhizoma Pinelliae, Radix Ginseng, Rhizoma Coptidis, the Radix Astragali, Rhizoma Dioscoreae, Cortex Moutan, Radix Achyranthis Bidentatae, Rhizoma Chuanxiong, Cortex Mori, the Radix Paeoniae Alba with described weight adds 6 times of water gagings, intense fire decocts boiling 20 minutes, used again slow fire boiling 20 minutes, filter, get for the first time decoction liquor;
(2) medicinal residues that filter are added 3 times of amounts of water, intense fire decocts, and simmers in water 20 minutes again, filters, and gets for the second time decoction liquor;
(3) decoct medicinal liquid with twice and merge, mix homogeneously, intense fire boils, and uses slow fire boiling 10 minutes again, must take medicinal liquid, and medicinal liquid is divided into 4 doses.
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