CN102850452A - 用于抑制内源性免疫球蛋白基因和生产转基因人独特型抗体的组合物和方法 - Google Patents
用于抑制内源性免疫球蛋白基因和生产转基因人独特型抗体的组合物和方法 Download PDFInfo
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- CN102850452A CN102850452A CN2012103019509A CN201210301950A CN102850452A CN 102850452 A CN102850452 A CN 102850452A CN 2012103019509 A CN2012103019509 A CN 2012103019509A CN 201210301950 A CN201210301950 A CN 201210301950A CN 102850452 A CN102850452 A CN 102850452A
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Abstract
Description
靶残基 | 靶残基 | ||
YN-TS5-L | Q26和S32 | YN-TS6-L | Q26、K28和R68 |
YN-TS5-Ri1 | R68、R70和D75 | YN-TS6-Ri1 | Q44和R68 |
YN-TS5-Ri2 | Q26和K28 | YN-TS6-Ri2 | N30、Y33和Q38 |
YN-TS5-Ri3 | N30、Y33和Q38 |
Claims (16)
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US94161907P | 2007-06-01 | 2007-06-01 | |
US60/941,619 | 2007-06-01 | ||
US4432408P | 2008-04-11 | 2008-04-11 | |
US61/044,324 | 2008-04-11 |
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CN2008801012988A Division CN101784664B (zh) | 2007-06-01 | 2008-05-30 | 用于抑制内源性免疫球蛋白基因和生产转基因人独特型抗体的组合物和方法 |
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CN102850452A true CN102850452A (zh) | 2013-01-02 |
CN102850452B CN102850452B (zh) | 2019-07-16 |
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Publication number | Priority date | Publication date | Assignee | Title |
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US12016313B2 (en) | 2017-01-19 | 2024-06-25 | Omniab Operations, Inc. | Human antibodies from transgenic rodents with multiple heavy chain immunoglobulin loci |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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US12016313B2 (en) | 2017-01-19 | 2024-06-25 | Omniab Operations, Inc. | Human antibodies from transgenic rodents with multiple heavy chain immunoglobulin loci |
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