CN102824549B - 一种治疗胃阴虚的中药 - Google Patents
一种治疗胃阴虚的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗胃阴虚的中药，采用以下重量配比的药材制备而成：番泻叶15份、玉竹25份、罗汉果15份、麦冬25份、石斛15份、瓜蒌15份、火麻仁15份、马尾连15份、鸡金炭30份、橘白15份、沙参15份、生地15份、枳壳15份、神曲15份、大黄10份、香附15份、甘草15份。实验证明，本发明能够安全有效治疗胃阴虚。
Description
技术领域
本发明涉及一种中药，具体涉及一种治疗胃阴虚的中药。
背景技术
胃阴虚是指胃的阴液不足所出现的证候，又称胃阴不足。证见口干唇燥，嘈杂，干呕，饮食减少，或吞咽不利，食后胸膈不适，大便干结，舌红中心干，少苔，或舌光、干绛，脉细数等。目前治疗采用的药物有较大的毒副作用，成本高，易反复，治愈率低，在治疗效果方面不能令人满意。因此研究开发一种安全有效治疗胃阴虚的中药非常有实用价值。
本发明中药所涉及药材的研究现状如下：
番泻叶：【来源】本品为豆科植物狭叶番泻 Cassia angustifolia Vahl或尖叶番泻 Cassia acutifolia Delile 的干燥小叶。【功能主治】泻热行滞，通便，利水。用于热结积滞，便秘腹痛，水肿胀满。
玉竹：【来源】本品为百合科植物玉竹Polygonatum odoratum （Mill.）Druce的干燥根茎。【功能主治】养阴润燥，生津止渴。用于肺胃阴伤，燥热咳嗽，咽干口渴，内热消渴。
罗汉果：【来源】本品为葫芦科植物罗汉果Momordica grosvenori Swingle 的干燥果实。【功能主治】清热润肺，滑肠通便。用于肺火燥咳，咽痛失音，肠燥便秘。
麦冬：【来源】本品为百合科植物麦冬（沿阶草）Ophiopogon japonicus （Thunb.）Ker-Gawl.的干燥块根。【功能主治】养阴生津，润肺清心。用于肺燥干咳。虚痨咳嗽，津伤口渴，心烦失眠，内热消渴，肠燥便秘；咽白喉。
石斛：【来源】本品为兰科植物环草石斛Dendrobium loddigesii Rolfe. 、马鞭石斛Dendrobium fimbriatum Hook. var. oculatum Hook . 、黄草石斛Dendrobium chrysanthum Wall. 、铁皮石斛Dendrobium candidum Wall. ex Lindl. 或金钗石斛Dendrobium nobile Lindl. 的干燥茎。【功能主治】益胃生津，滋阴清热。用于阴伤津亏，口干烦渴，食少干呕，病后虚热，目暗不明。
瓜蒌：【来源】本品为葫芦科植物栝楼Trichosanthes kirilowii Maxim. 或双边栝楼Trichosan-thes rosthornii Harms 的干燥成熟果实。【功能主治】清热涤痰，宽胸散结，润肠。用于肺热咳嗽，痰浊黄稠，胸痹心痛，乳痈、肺痈、肠痈肿痛。
火麻仁：【来源】本品为桑科植物大麻Cannabis sativa L.的干燥成熟果实。【功能主治】润肠通便。用于血虚津亏，肠燥便秘。
马尾连：【来源】为毛茛科唐松草属植物多叶唐松草Thalictrum foliolosum DC. 及高原唐松草T.cultratum Wall.[T. deciternatum Boiv]，以根部入药。【功能主治】清热燥湿，泻火解毒。用于肠炎，痢疾，黄疸，目赤肿痛。
枳壳：【来源】本品为芸香科植物酸橙Citrus aurantium L.及其栽培变种的干燥未成熟果实。【功能主治】理气宽中，行滞消胀。用于胸胁气滞，胀满疼痛，食积不化，痰饮内停；胃下垂，脱肛，子官脱垂。
鸡金炭：【来源】雉科动物鸡的沙囊内膜洗净烧成炭灰。【功能主治】健脾消食；涩精止遗；消症化石。主消化不良；饮食积滞；呕吐反胃；泄泻下痢；小儿疳积；遗精；遗尿；小便频数；泌尿系结石及胆结石；症瘕经闭；喉痹乳蛾；牙疳口疮。
橘白：【来源】为芸香科植物福橘或朱橘等多种橘类果皮的白色内层部分。【功能主治】和胃化湿。主湿浊内阻；胸脘痞满；食欲不振。
沙参：【来源】为桔梗科沙参属植物四叶沙参Adenophora tetraphylla （Thunb.） Fisch.[A. berticillata （Pall.） Fisch.]、杏叶沙参A. axilliflora Borb [A. stricta Miq.]或其同属植物，以根入药。【功能主治】清热养阴，润肺止咳。主治气管炎，百日咳，肺热咳嗽，咯痰黄稠。
生地：【来源】本品为玄参科植物地黄Rehmannia glutinosa Libosch. 的干燥块根。【功能主治】清热凉血，养阴，生津。用于热病舌绛烦渴，阴虚内热，骨蒸劳热，内热消渴，吐血，衄血，发斑发疹。
神曲：【来源】为辣蓼、青蒿、杏仁等药加入面粉或麸皮混和后，经发酵而成的曲剂。【功能主治】健脾和胃，消食调中。治饮食停滞，胸痞腹胀，呕吐泻痢，产后瘀血腹痛，小儿腹大坚积。
大黄：【来源】本品为蓼科植物掌叶大黄Rheum palmatum L。、 唐古特大黄Rheum tanguticum Maxim。 ex Balf。或药用大黄Rheum officinale Baill。的干燥根及根茎。【功能主治】泻热通肠，凉血解毒，逐瘀通经。用于实热便秘，积滞腹痛，泻痢不爽，湿热黄疸，血热吐衄，目赤，咽肿，肠痈腹痛，痈肿疔疮，瘀血经闭，跌打损伤，外治水火烫伤；上消化道出血。酒大黄善清上焦血分热毒。用于目赤咽肿，齿龈肿痛。熟大黄泻下力缓，泻火解毒。用于火毒疮疡。大黄炭凉血化瘀止血。用于血热有瘀出血症。
香附：【来源】本品为莎草科植物莎草Cyperus rotundus L. 的干燥根茎用通便炮制。【功能主治】行气解郁，调经止痛。用于肝郁气滞，胸、胁、脘腹胀痛，消化不良，胸脘痞闷，寒疝腹痛，乳房胀痛，月经不调，经闭痛经。
山药：【来源】本品为薯蓣科植物薯蓣Dioscorea opposita Thunb. 的干燥根茎。【功能主治】补脾养胃，生津益肺，补肾涩精。用于脾虚食少，久泻不止，肺虚喘咳，肾虚遗精，带下，尿频，虚热消渴。
甘草：【来源】本品为豆科植物甘草 Glycyrrhiza uralensis Fisch.、胀果甘草 Glycyrrhiza inflata Bat. 或光果甘草 Glycyrrhiza glabra L. 的干燥根。【功能主治】补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。
发明内容
本发明旨在提供一种治疗胃阴虚的中药，通过选择合适的药材及其配比，达到安全有效治愈胃阴虚的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗胃阴虚的中药，其特征在于，采用以下重量配比的药材制备而成：番泻叶15份、玉竹25份、罗汉果15份、麦冬25份、石斛15份、瓜蒌15份、火麻仁15份、马尾连15份、鸡金炭30份、橘白15份、沙参15份、生地15份、枳壳15份、神曲15份、大黄10份、香附15份、甘草15份。 下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2010年6月-2011年8月间共收集75例胃阴虚的门诊患者，其中，男15例，女60例，年龄30-60岁，病程1-12年。随机分为：治疗组50例，对照组25例。两组年龄等资料无显著性差异，具有可比性。
2、试验方法
2.1对照组服用香砂养胃丸，按照其说明书服用，疗程3周。
2.2治疗组服用本发明按照具体实施例1制得的成药，早晚各一次，疗程3周。
2.3观察项目：治疗前后胃脘嘈杂作疼，胸闷腹胀，大便干结，食量变化等症状。观察三个月有无反复。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状全部消失，试验室检查正常。好转：临床症状减轻，实验室检查改善或正常。无效：临床症状无明显好转或加重。
3.2治疗统计结果见表1。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率(%) |
| 治疗组 | 50 | 38（76%)） | 10（20%） | 2（4% ） | 96% |
| 对照组 | 25 | 16（64%)） | 2（8%)） | 7（28%） | 72% |
可见，本发明制得的药物能够安全有效治疗胃阴虚。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取番泻叶15克、玉竹25克、罗汉果15克、麦冬25克、石斛15克、瓜蒌15克、火麻仁15克、马尾连15克、鸡金炭30克、橘白15克、沙参15克、生地15克、枳壳15克、神曲15克、大黄10克、香附15克、甘草15克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，浓缩，干燥，装入胶囊壳，即得符合正常成人3天用量的胶囊剂。
用于治疗胃阴虚。口服，每日分早晚两次服用。
具体实施例2
称取番泻叶15克、玉竹25克、罗汉果15克、麦冬25克、石斛15克、瓜蒌15克、火麻仁15克、马尾连15克、鸡金炭30克、橘白15克、沙参15克、生地15克、枳壳15克、神曲15克、大黄10克、香附15克、甘草15克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人3天用量的颗粒剂。
用于治疗胃阴虚。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗胃阴虚的中药，其特征在于，采用以下重量配比的药材制备而成：番泻叶15份、玉竹25份、罗汉果15份、麦冬25份、石斛15份、瓜蒌15份、火麻仁15份、马尾连15份、鸡金炭30份、橘白15份、沙参15份、生地15份、枳壳15份、神曲15份、大黄10份、香附15份、甘草15份。
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1387889A (zh) * | 2002-06-15 | 2003-01-01 | 合肥神鹿双鹤药业有限责任公司 | 治疗脾胃阴虚型萎缩性胃炎的中药制剂 |
| CN1454635A (zh) * | 2003-02-14 | 2003-11-12 | 申泰富 | 八味和胃口服液及其制备工艺 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1387889A (zh) * | 2002-06-15 | 2003-01-01 | 合肥神鹿双鹤药业有限责任公司 | 治疗脾胃阴虚型萎缩性胃炎的中药制剂 |
| CN1454635A (zh) * | 2003-02-14 | 2003-11-12 | 申泰富 | 八味和胃口服液及其制备工艺 |
Non-Patent Citations (2)
| Title |
|---|
| 杨天谷等.浅述脾阴虚与胃阴虚之联系与区别.《河南中医》.2010,第30卷(第1期),17-20. |
| 浅述脾阴虚与胃阴虚之联系与区别;杨天谷等;《河南中医》;20100131;第30卷(第1期);17-20 * |
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