CN102824328A - Collagen effervescent tablet - Google Patents
Collagen effervescent tablet Download PDFInfo
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- CN102824328A CN102824328A CN2012103338453A CN201210333845A CN102824328A CN 102824328 A CN102824328 A CN 102824328A CN 2012103338453 A CN2012103338453 A CN 2012103338453A CN 201210333845 A CN201210333845 A CN 201210333845A CN 102824328 A CN102824328 A CN 102824328A
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Abstract
The invention belongs to the field of health-care products and particularly relates to a collagen effervescent tablet. The collagen effervescent tablet is prepared from the following raw materials in weight ratio: 647.1 parts of collagen powder, 186.7 parts of sodium bicarbonate, 120.7 parts of citric acid monohydrate, 20 parts of cane sugar, 9.5 parts of povidone, 6 parts of sodium hydroxide and 10 parts of edible essence, wherein the weight-average relative molecular weight of the povidone is 2000. The collagen effervescent tablet has the advantages that the disintegration time is short; the dissolving-out speed is high; the nutritive value of collagen can be fully performed; the bioavailability is high; expenditures are saved for consumers; and energy sources are saved.
Description
Technical field
The invention belongs to field of health care products, particularly a kind of collagen protein effervescent tablet.
Background technology
Collagen protein is a kind of biological polymer substance, is a kind of white, opaque, unbranched fibroid protein.It can replenish the required nutrition of each layer of skin, makes collagen increased activity in the skin, skin care is arranged, effects such as slow down aging, beauty treatment, wrinkle-chasing, hair care.Collagen protein is the nutrient substance that the human body slow down aging must be supplied, and accounts for more than 30% of human body whole body gross protein, and 3 kilograms of collagen protein are arranged in the adult health approximately.It is present in the skin, skeleton, muscle, cartilage, joint, hair tissue of human body widely, plays triple anti-aging effects of support, reparation, protection.
With advancing age, the loss that collagen protein can be gradually.Women's collagen protein in the time of 20 years old has begun to wear out, run off, and content descends year by year, the peak period of then get into running off in 25 years old; In the time of 40 years old, content half the during less than 18 years old, the old people is the wrinkle of ditch ditch bank on the face; Exactly because collagen protein and water loss cause skin to subside.The loss of collagen protein causes supporting the collagen peptide bond and the elasticated net fracture of skin, and its spiral RF is destroyed immediately, and skin histology is oxidized, atrophy, subside, and drying, wrinkle, aging phenomenon such as lax nonelastic will appear in skin.So, the slow down aging must replenishing collagen.
At present, in the existing collagen protein product, be mostly facial film, oral liquid etc., the tablet product is seldom arranged, facial film uses cumbersome, and also inconvenience that have are taken, carried to oral liquid more.
Application number is 200910188834.9; Name is called the Chinese invention patent application of " compound preparation of a kind of collagen protein sheet and preparation method thereof "; A kind of collagen protein sheet that contains collagen protein powder, vitamin, honey peach essence is disclosed; Do not mention the dissolution and the bioavailability of this tablet, how can not understand its drug effect.
Effervescent tablet is a kind of novel tablet of external Application and Development in this year.The difference of it and conventional tablet; Just be that it also contains gas-producing disintegrant, after effervescent tablet is put into drinking-water, under the effect of gas-producing disintegrant; At once produce great amount of bubbles (carbon dioxide); Make rapid disintegrate of tablet and thawing, the bubble that disintegrate sometimes produces also can make tablet in water, roll up and down, quickens its disintegrate and thawing.The carbon dioxide that produces during disintegration of tablet is partially dissolved in the drinking-water, making drinking-water that the aesthetic feeling as the soda pop arranged when drinking in the inlet.Though collagen protein effervescent tablet product is also arranged now on the market, and dissolution velocity is slow, the product dissolution is low, and bioavailability is low, can not give full play to the effect of collagen protein.
Summary of the invention
In order to solve the problem that use is loaded down with trivial details, the effervescent tablet dissolution velocity slow, the product dissolution is low, bioavailability is low that occurs in the above existing collagen protein use, the invention provides the collagen protein effervescent tablet that a kind of dissolution is high, dissolution velocity is fast, bioavailability is high.
The present invention realizes through following measure:
A kind of collagen protein effervescent tablet, process by following materials of weight proportions:
647.1 parts of collagen protein powders, 186.7 parts of sodium bicarbonate, 120.7 parts of citric acid monohydrate, 20 parts of sucrose, 9.5 parts of polyvidones, 6 parts of sodium hydroxide, 10 parts of edible essences;
The average weight-molecular mass of polyvidone is 2000.
Described collagen protein effervescent tablet, each raw materials mix is even, spray 90% alcoholic solution and make it moistening, granulate oven dry, intermediate survey, granulate, tabletting;
Every 1000g raw material uses 90% alcoholic solution 156g.
Described collagen protein effervescent tablet is processed the tablet of 0.1 gram/sheet.
Beneficial effect of the present invention: collagen protein effervescent tablet of the present invention, disintegration time is short, and dissolution is high, can give full play to the nutritive value of collagen protein, and bioavailability is high, for consumer reduces expenses, energy savings.Collagen protein effervescent tablet of the present invention has skin protection, and hair care replenishes collagen protein required in skeleton, blood vessel, the muscle or the like effect.
The specific embodiment
For a better understanding of the present invention, further specify below in conjunction with specific embodiment.
Embodiment:
A kind of collagen protein effervescent tablet, process by following materials of weight proportions:
647.1 parts of collagen protein powders, 186.7 parts of sodium bicarbonate, 120.7 parts of citric acid monohydrate, 20 parts of sucrose, 9.5 parts of polyvidones, 6 parts of sodium hydroxide, 10 parts of edible essences;
The average weight-molecular mass of polyvidone is 2000.
Method for preparing: each raw materials mix is even, spray 90% alcoholic solution and make it moistening, granulate oven dry, intermediate survey, granulate, tabletting; Every 1000g raw material uses 90% alcoholic solution 156g.
Process the tablet of 1.0 gram/sheets.
Usage and dosage: get these article and put into water, rapidly disintegrate and thawing, to disintegrate with melt fully i.e. edible.
These article are taken before suiting to sleep, every day 1 time, each 4-6 sheet.
The dissolution velocity experiment:
These article use the hanging basket method to measure:
Measure the purified water 900ml that handles through the degassing, inject in each process container, heating makes solvent temperature remain on 37 ± 0.5 ℃, and the adjustment rotating speed makes it stable.Getting the test sample input changes in the basket, will change basket and fall in the container, picks up counting immediately; During to 20 seconds, 60 seconds, 5 minutes, 20 minutes and 45 minutes; An amount of in regulation sample point draw solution respectively, filter through 0.8 μ m microporous filter membrane immediately, being sampled to filtration certainly should accomplish in 30 seconds.Get filtrating, measure trap at the 500nm place, measure result such as following table (adopting on the market generally, the excellent preferably happy collagen protein effervescent tablet of reflection compares) through UV-VIS spectrophotometry:
Use and observe:
(1) Zhang, the woman, 40 years old, cutis laxa, dark yellow, lackluster, there is microgroove at the canthus.Take health food of the present invention, take before sleeping every night 1 time, each 6, skin obviously improves after 45 days, and the colour of skin has lifting, the desalination of canthus microgroove, and skin is more flexible.
(2) grandson, the woman, 31 years old, the colour of skin was yellow partially, and face has slight red blood streak, dry hair.Take health food of the present invention, take before sleeping every night 1 time, each 4, skin obviously improves after 30 days, and the colour of skin is ruddy, even, flexible, and hair is rich in gloss.
Claims (3)
1. collagen protein effervescent tablet is characterized in that being processed by following materials of weight proportions:
647.1 parts of collagen protein powders, 186.7 parts of sodium bicarbonate, 120.7 parts of citric acid monohydrate, 20 parts of sucrose, 9.5 parts of polyvidones, 6 parts of sodium hydroxide, 10 parts of edible essences;
The average weight-molecular mass of polyvidone is 2000.
2. collagen protein effervescent tablet according to claim 1 is characterized in that each raw materials mix evenly, sprays 90% alcoholic solution and makes it moistening, granulates oven dry, intermediate survey, granulate, tabletting;
Every 1000g raw material uses 90% alcoholic solution 156g.
3. collagen protein effervescent tablet according to claim 2 is characterized in that processing the tablet of 1.0 gram/sheets.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012103338453A CN102824328A (en) | 2012-09-11 | 2012-09-11 | Collagen effervescent tablet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012103338453A CN102824328A (en) | 2012-09-11 | 2012-09-11 | Collagen effervescent tablet |
Publications (1)
| Publication Number | Publication Date |
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| CN102824328A true CN102824328A (en) | 2012-12-19 |
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Family Applications (1)
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| CN2012103338453A Pending CN102824328A (en) | 2012-09-11 | 2012-09-11 | Collagen effervescent tablet |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104824660A (en) * | 2015-04-08 | 2015-08-12 | 王书敏 | Collagen-saussurea involucrata small peptide effervescent tablet and preparation method thereof |
| CN104904990A (en) * | 2014-03-12 | 2015-09-16 | 苏州吉利鼎海洋生物科技有限公司 | Preparation method of porous collagen particles |
| CN110628853A (en) * | 2019-08-29 | 2019-12-31 | 北京市林业果树科学研究院 | Walnut antioxidant active peptide and preparation method and application thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101130067A (en) * | 2007-07-20 | 2008-02-27 | 北京世纪博康医药科技有限公司 | Preparation for replenishing collagen and method of preparing the same |
-
2012
- 2012-09-11 CN CN2012103338453A patent/CN102824328A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101130067A (en) * | 2007-07-20 | 2008-02-27 | 北京世纪博康医药科技有限公司 | Preparation for replenishing collagen and method of preparing the same |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104904990A (en) * | 2014-03-12 | 2015-09-16 | 苏州吉利鼎海洋生物科技有限公司 | Preparation method of porous collagen particles |
| CN104824660A (en) * | 2015-04-08 | 2015-08-12 | 王书敏 | Collagen-saussurea involucrata small peptide effervescent tablet and preparation method thereof |
| CN110628853A (en) * | 2019-08-29 | 2019-12-31 | 北京市林业果树科学研究院 | Walnut antioxidant active peptide and preparation method and application thereof |
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| C12 | Rejection of a patent application after its publication | ||
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Application publication date: 20121219 |