CN102824161B - Ophthalmologic OCT (Optical Coherence Tomography) system and ophthalmologic OCT imaging method - Google Patents
Ophthalmologic OCT (Optical Coherence Tomography) system and ophthalmologic OCT imaging method Download PDFInfo
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- CN102824161B CN102824161B CN201210338019.8A CN201210338019A CN102824161B CN 102824161 B CN102824161 B CN 102824161B CN 201210338019 A CN201210338019 A CN 201210338019A CN 102824161 B CN102824161 B CN 102824161B
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- 238000012014 optical coherence tomography Methods 0.000 title abstract description 54
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Abstract
The invention discloses an ophthalmologic OCT (Optical Coherence Tomography) system and an ophthalmologic OCT imaging method. The OCT system comprises a light source, a coupler, a reference arm, a sample arm, a spectrograph and a computer processing unit, wherein the sample arm comprises a polarization controller, a sample arm focusing lens, a two-dimensional galvanometer unit, a diopter adjustment lens, an eye and object lens, a light path switching galvanometer and a reflector unit; the light path switching galvanometer comprises at least two turn angles; emergent light from a sample arm focusing lens is incident into the light path switching galvanometer and reflected by the light path switching galvanometer; the light path switching galvanometer controls the emergent angle of the emergent light through different turn angles, so that the emergent light can be incident into the two-dimensional galvanometer unit through different light paths; and the different light paths comprise a light path in which the light is directly incident into the two-dimensional galvanometer unit from the light path switching galvanometer and a light path in which the light is reflected through the reflector unit and incident into the two-dimensional galvanometer unit. According to the ophthalmologic OCT system and the ophthalmologic OCT imaging method, large-range fundus OCT scanning can be finished.
Description
Technical field
The present invention relates to optical coherence tomography (English is: Optical Coherence Tomography, initialism is: OCT) technology, especially relate to ophthalmology OCT system and ophthalmology OCT formation method.
Background technology
Tradition time domain OCT system, reference arm vibrates to realize certain depth range detection, but the degree of depth is limited, and this depth location scope can allow carrys out light modulation journey before and after fiber optic collimator mirror in reference arm or sample arm.But before and after fiber optic collimator mirror, the driven by motor that adopt, cannot realize the quick switching of investigative range more.Traditional frequency domain OCT system, reference arm maintains static, and carrys out light modulation journey before and after the fiber optic collimator mirror by sample arm, and before and after same fiber optic collimator mirror, the driven by motor that adopt, cannot realize the quick switching of investigative range more.And optical fundus on a large scale tomoscan be imaged on and in doctor's clinical diagnosis, have important directive function.Due to the automatic minute movement of human eye club, and this moves and seesaws and cannot ignore with respect to motor, and the OCT system of time domain or frequency domain all cannot be accomplished quick-speed large-scale optical fundus scanning imagery.
Summary of the invention
Technical problem to be solved by this invention is: provide a kind of ophthalmology OCT system with ophthalmology OCT formation method, for realizing optical fundus OCT image scanning on a large scale.
A kind of ophthalmology OCT system, comprise light source, bonder, reference arm, sample arm, spectrogrph and computer processing unit, wherein, described sample arm comprises Polarization Controller, sample arm focusing lens, 2-D vibration mirror unit, diopter adjusting mirror and connects order object lens, described sample arm also comprises: optical path switch module and mirror unit, wherein, described optical path switch module comprises at least two corners;
The emergent light of described sample arm focusing lens is incident to described optical path switch module, and reflected by described optical path switch module, thereby described optical path switch module makes its emergent light to be incident to described 2-D vibration mirror unit through the light path of different light paths by the shooting angle of different its emergent lights of controlling angle; The light path of described different light paths comprise from described optical path switch module outgoing directly into being incident upon the light path of described 2-D vibration mirror unit and being incident to again the light path of described 2-D vibration mirror unit after the reflection of described mirror unit.
Preferably, described optical path switch module is that light path is switched galvanometer.
Preferably, described mirror unit comprises one, two or more reflecting mirror, and described reflecting mirror is respectively used to receive the emergent light of the different shooting angles of described optical path switch module and reflex to described 2-D vibration mirror unit.
An optical fundus OCT formation method for aforesaid ophthalmology OCT system, is characterized in that, comprises the following steps:
1), in the scanning process of optical fundus, control the light path of optical path switch module switch sample arm;
2) utilize the OCT signal of surveying center, optical fundus recess from described optical path switch module outgoing directly into the light path that is incident upon described 2-D vibration mirror unit, utilize the light path that is incident to again described 2-D vibration mirror unit after described optical path switch module outgoing after described mirror unit reflection to survey center, optical fundus recess OCT signal around;
3) analyze the OCT signal of center, described optical fundus recess and the OCT image of center, optical fundus recess OCT signal acquisition optical fundus diverse location around;
4) described OCT image is spliced to form to complete optical fundus scintigram.
Preferably, in the OCT image of optical fundus diverse location described in described step 3), the OCT image of adjacent position overlaps; Described step 4) utilizes described lap to splice described OCT image.
In ophthalmology OCT system of the present invention, sample arm not only can move forward and backward the front and back of deciding investigative range by sample arm focusing lens, and the quick rotation switching-over light path that can switch galvanometer by light path is to realize the adjusting of light path, therefore, compared with prior art, ophthalmology OCT system of the present invention not only can realize the scanning of enough degree of depth, and can very short moment complete center, optical fundus recess and around the scanning of different depth scope, thereby avoided human eye to rotate, OCT is scanned to the impact causing.Switches realization because quick light path of the present invention regulates by light path, but not used quick mobile optical components and parts realization, therefore also there will not be Doppler effect and affect signal quality.
Brief description of the drawings
Fig. 1 be the ophthalmology OCT system of the specific embodiment of the invention 1 from light source the structural representation to 2-D vibration mirror unit;
Fig. 2 be the ophthalmology OCT system of the specific embodiment of the invention 1 from 2-D vibration mirror unit the light path schematic diagram to sample;
Fig. 3 is the fundus image imaging schematic diagram of the ophthalmology OCT system of the specific embodiment of the invention 1;
Fig. 4 is the structural representation that the light path of the ophthalmology OCT system of the specific embodiment of the invention 2 is switched galvanometer, mirror unit and 2-D vibration mirror unit;
Fig. 5 is the structural representation that the light path of the ophthalmology OCT system of the specific embodiment of the invention 3 is switched galvanometer, mirror unit and 2-D vibration mirror unit.
Description of reference numerals:
S, sample (human eye)
Er, human eye optical fundus
101, OCT system source
102, bonder
103, examine arm focusing lens
104, reflecting mirror
105, Polarization Controller
106, sample arm focusing lens
107, light path is switched galvanometer
108, the 2-D vibration mirror of X-direction
109, the 2-D vibration mirror of Y direction
110, diopter adjusting mirror
111, connect order object lens
201, spectrogrph
202, computer processing unit
M1～M9 reflecting mirror
L1～L9 light path
Detailed description of the invention
Preferred embodiment the invention will be further described to contrast accompanying drawing combination below.
The ophthalmology OCT system of the present embodiment, comprises light source 101, bonder 102, reference arm, sample arm, spectrogrph 201 and computer processing unit 202.
Wherein, reference arm is made up of reference arm focusing lens 103 and reflecting mirror 104; Sample arm is switched galvanometer 107, mirror unit, 2-D vibration mirror unit, diopter adjusting mirror 110 and is connect order object lens 111 by Polarization Controller 105, sample arm focusing lens 106, as the light path of optical path switch module and forms.
The emergent light of described sample arm focusing lens is incident to described light path and switches galvanometer 107, and reflected by described light path switching galvanometer 107, thereby described light path switching galvanometer 107 makes its emergent light to be incident to described 2-D vibration mirror unit through different light paths by the shooting angle of different its emergent lights of controlling angle; Described different light path comprises from the outgoing of described light path switching galvanometer directly into being incident upon described 2-D vibration mirror unit and being incident to described 2-D vibration mirror unit again after described mirror unit reflection.
Embodiment 1
As shown in Figure 1, the 2-D vibration mirror unit of the present embodiment comprises the 2-D vibration mirror 108 of directions X and the 2-D vibration mirror 109 of Y-direction, mirror unit comprises mirror M 1 and 2 two reflecting mirrors of mirror M, light path is switched galvanometer 107 and is comprised three different corners, corresponds respectively to three different light paths: L1) light path switch galvanometer 107 emergent light after mirror M 1 reflection outgoing to 2-D vibration mirror 108 center; L2) the direct outgoing of emergent light that light path is switched galvanometer 107 is to 2-D vibration mirror 108 center; L3) emergent light that light path is switched galvanometer 107 after mirror M 2 reflection outgoing to 2-D vibration mirror 108 centers.As shown in Figure 3, human eye optical fundus ER radius of curvature is about 12.3mm, is imaged as the curve in fundus image shown in Fig. 3 through connecing thing eyepiece 111, because the light path light path of three light paths is different, wherein, the light path light path of light path L2 is the shortest, when corresponding OCT surveys, Aplanatic Surface position farthest, just consistent with fundus image curved surface bending direction, therefore, light path L2 is for surveying the OCT signal of center, optical fundus recess, and L1 and L3 light path are also different, be respectively used to the OCT signal on both sides, optical fundus.
The work process of the OCT system of the present embodiment is as follows:
While scanning on optical fundus, keep human eye S front and back position motionless, light source emergent light is through bonder, and a road is to sample arm, and a road is to reference arm, and the light of reference arm is reflected Yan Yuan road by the reflecting mirror 104 of sample arm and turns back to bonder after reference arm focusing lens 103.The light of sample arm is incident to light path and switches galvanometer 107 after Polarization Controller 105, sample arm focusing lens 106, switch in three different corners by controlling light path switching galvanometer 107, light path is as shown in Figure 1 switched galvanometer 107 around the axle rotation perpendicular to paper, and light can be through three different light path outgoing to 2-D vibration mirror 108 center; Rotating 2-D vibration mirror 108 makes light reflex to 2-D vibration mirror 109 through 2-D vibration mirror 108, pass through again diopter adjusting mirror 110 and connect thing eyepiece 111 and enter human eye, human eye returns to Guang Jingyuan road and is back to bonder 102, and the light interference of returning with reference arm, this interference signal enters spectrogrph 201, and reconciled and then conciliation signal is passed to computer processing unit 202 and process by spectrogrph, obtain optical fundus scintigram.Wherein, utilize light path L2 to survey the OCT signal of the OCT signal center recess of center, optical fundus recess, utilize L1 and L3 to survey the OCT signal of both sides, optical fundus different depth position; The OCT system of the present embodiment utilizes three tunnel light paths can obtain 5 images of opening one's eyes end diverse location, as shown in Figure 3, in 5 eye fundus images, the image of adjacent position overlaps, and computer processing unit can utilize this lap to carry out image recognition and be spliced into complete optical fundus scintigram.
Embodiment 2,
The difference of the present embodiment and embodiment 1 is only mirror unit, the mirror unit of the present embodiment comprises three mirror M 3, M4, M5, these three reflecting mirrors are respectively used to form light path L4, L7, the L6 of a specific light path in road, and therefore the OCT system of the present embodiment has the light path of the different light paths in four tunnels.
Embodiment 3
The difference of the present embodiment and embodiment 1 is only mirror unit, and the mirror unit of the present embodiment comprises four mirror M 6, M7, M8 and M9, and wherein M6, M7 are positioned at that light path L8 is upper, M8, M9 are positioned on light path L9.
Above content is in conjunction with concrete preferred implementation further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For those skilled in the art, without departing from the inventive concept of the premise, can also make some being equal to substitute or obvious modification, and performance or purposes identical, all should be considered as belonging to protection scope of the present invention.
Claims (5)
1. an ophthalmology OCT system, comprise light source, bonder, reference arm, sample arm, spectrogrph and computer processing unit, wherein, described sample arm comprises Polarization Controller, sample arm focusing lens, 2-D vibration mirror unit, diopter adjusting mirror and connects order object lens, it is characterized in that, described sample arm also comprises: optical path switch module and mirror unit, and wherein, described optical path switch module comprises at least two corners;
The emergent light of described sample arm focusing lens is incident to described optical path switch module, and reflected by described optical path switch module, thereby described optical path switch module makes its emergent light to be incident to described 2-D vibration mirror unit through the light path of different light paths by the shooting angle of different its emergent lights of controlling angle;
The light path of described different light paths comprises: from described optical path switch module outgoing directly into being incident upon the first light path of described 2-D vibration mirror unit and being incident to again the second light path of described 2-D vibration mirror unit after the reflection of described mirror unit, described the first light path is for surveying the OCT signal of center, optical fundus recess, and described the second light path is for surveying center, optical fundus recess OCT signal around.
2. OCT system according to claim 1, is characterized in that: described optical path switch module is that light path is switched galvanometer.
3. OCT system according to claim 1 and 2, it is characterized in that: described mirror unit comprises one, two or more reflecting mirror, described reflecting mirror is respectively used to receive the emergent light of the different shooting angles of described optical path switch module and reflex to described 2-D vibration mirror unit.
4. an optical fundus OCT formation method for ophthalmology OCT system as claimed in claim 1, is characterized in that, comprises the following steps:
1), in the scanning process of optical fundus, control the light path of optical path switch module switch sample arm;
2) utilize the OCT signal of surveying center, optical fundus recess from described optical path switch module outgoing directly into the light path that is incident upon described 2-D vibration mirror unit, utilize the light path that is incident to again described 2-D vibration mirror unit after described optical path switch module outgoing after described mirror unit reflection to survey center, optical fundus recess OCT signal around;
3) analyze the OCT signal of center, described optical fundus recess and the OCT image of center, optical fundus recess OCT signal acquisition optical fundus diverse location around;
4) described OCT image is spliced to form to complete optical fundus scintigram.
5. with optical fundus claimed in claim 4 OCT formation method, it is characterized in that: in the OCT image of optical fundus diverse location described in described step 3), the OCT image of adjacent position overlaps; Described step 4) utilizes described lap to splice described OCT image.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN103251382B (en) * | 2013-04-17 | 2015-10-14 | 温州医学院 | A kind of full eye domain optical coherence tomography system and method thereof |
| CN103674840B (en) * | 2013-11-18 | 2016-03-23 | 深圳市斯尔顿科技有限公司 | Debug the method for cartridge calibration scan device and debug cartridge and system |
| CN104224109B (en) * | 2014-10-16 | 2016-06-08 | 深圳市斯尔顿科技有限公司 | A kind of fundus camera in conjunction with OCT system |
| CN104318541B (en) * | 2014-11-19 | 2017-07-28 | 深圳市斯尔顿科技有限公司 | A kind of processing method of ophthalmology OCT image |
| CN105030202B (en) * | 2015-07-30 | 2018-01-12 | 武汉理工大学 | OCT image method based on the interference enhancing of core shift polarization maintaining optical fibre |
| CN106725287B (en) * | 2017-02-15 | 2018-11-09 | 佛山市同视科技有限公司 | A kind of non-cpntact measurement device and method of ocular biometric parameters |
| AU2018263623A1 (en) * | 2017-05-02 | 2019-10-10 | Alcon Inc. | Reconfigurable optical coherence tomography (OCT) system |
| US11602271B2 (en) | 2018-03-01 | 2023-03-14 | Alcon Inc. | Common path waveguides for stable optical coherence tomography imaging |
| CN109602396A (en) * | 2018-12-29 | 2019-04-12 | 执鼎医疗科技（杭州）有限公司 | A kind of breakdown formula all -fiber reference arm frequency sweep OCT system |
| CN110836852B (en) * | 2019-11-13 | 2024-03-26 | 深圳市斯尔顿科技有限公司 | Industrial OCT detection device and method |
| CN110793918B (en) * | 2019-11-13 | 2024-05-10 | 深圳市斯尔顿科技有限公司 | Industrial OCT detection device and method based on spatial free distribution light path |
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