CN104224109B - A kind of fundus camera in conjunction with OCT system - Google Patents
A kind of fundus camera in conjunction with OCT system Download PDFInfo
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- 230000003287 optical effect Effects 0.000 claims abstract description 56
- 238000003384 imaging method Methods 0.000 claims abstract description 39
- 239000000835 fiber Substances 0.000 claims abstract description 27
- 238000001514 detection method Methods 0.000 claims abstract description 23
- 238000005452 bending Methods 0.000 claims abstract description 6
- 230000026676 system process Effects 0.000 claims abstract description 3
- 239000000523 sample Substances 0.000 claims description 36
- 238000007598 dipping method Methods 0.000 claims description 25
- 230000021615 conjugation Effects 0.000 claims description 18
- 210000001747 pupil Anatomy 0.000 claims description 18
- 238000009792 diffusion process Methods 0.000 claims description 10
- 230000010287 polarization Effects 0.000 claims description 9
- 230000011514 reflex Effects 0.000 claims description 9
- 230000005540 biological transmission Effects 0.000 claims description 5
- 238000000034 method Methods 0.000 abstract description 12
- 230000008569 process Effects 0.000 abstract description 9
- 230000001276 controlling effect Effects 0.000 description 5
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- 210000004087 cornea Anatomy 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000001427 coherent effect Effects 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000006870 function Effects 0.000 description 1
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Abstract
The present invention discloses a kind of fundus camera in conjunction with OCT system, comprises OCT module, the first spectroscope, the 2nd spectroscope, the first perforate diaphragm, connects order object lens, illumination path and imaging optical path; OCT module provides reference light and detection light, and reference light returns after eyeground is reflected, and the reference light returned with reference arm module interferes at fiber coupler, and interference light is detected system looks and arrives, through Controlling System process, and the OCT image of display people's eye; Illumination path provides the illumination light being incident to people's eye eyeground, and this illumination light is incident to the imaging optical path of shooting people's eye eye fundus image after eyeground is reflected. Eyeground is being carried out in tomoscan imaging process by the present invention, detection light bends mirror without the need to the tune through imaging optical path, the OCT signal light power on incident people's eye eyeground can not be affected with adjusting the tune bending mirror to bend, thus obtain the good OCT tomoscan image on the different people's eye eyeground bending light.
Description
Technical field
The present invention relates to optoelectronic areas, refer more particularly to a kind of fundus camera combining OCT system.
Background technology
Existing fundus camera, usually bend, by adjusting of imaging optical path, the sharpness that mirror regulates infrared eyeground preview image, or bend optical system for alignment according to auxiliary tune and judge whether that tune is bent imaging optical path is adjusted to optimum regime, and then take pictures by ophthalmology OCT system execution photoflash lamp, obtain eye fundus image. But the sharpness of the eye fundus image obtained in this way is not high enough. In addition, application number is the technique means disclosing a kind of imaging optical path that OCT unit accesses fundus camera of the patent application document of 200710302263.8, and this kind of method can improve the sharpness of eye fundus image. But, in that patent, also existing defects. With reference to Fig. 1 of Figure of description and the 3rd section of reference the 8th page, specification sheets of this patent. In FIG, the flashlight that OCT unit 150 sends is after connection section 151, again successively through hole portion 112a and the object lens 113 of lens 142, scanning element 141, dichroic mirror 134, capture lens 126, relaying lens 125, variable power lens 124, shooting aperture 121, perforate eyeglass 112, finally it is incident to people eye E. Can learning from above, flashlight can enter people eye E after needing the tune through variable power lens 124 (being also exactly adjust to bend mirror) to bend. Therefore, to, in the OCT tomoscan process of eyeground, the tune of variable power lens 124 is bent and can be affected the OCT signal light power inciding people's eye eyeground.
Summary of the invention
The present invention provides a kind of fundus camera in conjunction with OCT system, its object is to solution and is being carried out on eyeground in OCT tomoscan process, affects the problem of the OCT signal light power on incident people's eye eyeground because light path tune is bent.
The technical scheme of the present invention is as follows:
In conjunction with a fundus camera for OCT system, comprising: OCT module, the first spectroscope, the 2nd spectroscope, be embedded with the perforate speculum of the first perforate diaphragm, connect order object lens, illumination path and imaging optical path; The light that the OCT system source of described OCT module sends obtains detection light and reference light through fiber coupler light splitting; Described detection light focuses on people's eye eyeground through the first spectroscope, the 2nd spectroscope, the first perforate diaphragm with after connecing order object lens successively after sample arm module, it is back to described fiber coupler after eyeground is reflected, and the reference light returned with the reference arm module being subordinated to described OCT module interferes at fiber coupler and forms interference light, interference light is detected system looks and arrives, through Controlling System process, the OCT image of display people's eye; The illumination light that described illumination path sends is incident to people's eye eyeground, is incident to described imaging optical path after eyeground is reflected; Described imaging optical path comprises: described in connect order object lens, described first perforate diaphragm, described 2nd spectroscope, adjust bend mirror, imaging lens, the 3rd spectroscope and camera device; Described sample arm module comprises relaying lens, two-dimensional scan device and eyeground OCT and adjusts mirror in the wrong, and described relaying lens are fixedly installed near described first spectroscope; Conjugation near described two-dimensional scan device and people's eye pupil; The fiber device of described camera device and described sample arm module all with people's eye eyeground conjugation.
Further: described illumination path comprise illumination module, described in be embedded with the perforate speculum of the first perforate diaphragm and described connect order object lens; The illumination light that described illumination module sends connects order object lens and illuminates eyeground described in reflexing to through described perforate speculum.
Further: described illumination module comprises: the infrared preview lighting source in eyeground, eyeground photoflash lamp take pictures light source, lighting source spectroscope, illumination path first lens, diffusion plate, bright dipping diaphragm, constraint diaphragm, illumination path the 2nd lens, stain plate, illumination path the 3rd lens and illumination diaphragm; The infrared preview in described eyeground lighting source, after described lighting source spectroscope reflects, is incident to described perforate speculum successively after described illumination path first lens, described diffusion plate, described bright dipping diaphragm, described constraint diaphragm, described illumination path the 2nd lens, described stain plate, described illumination path the 3rd lens and described illumination diaphragm; Or, photoflash lamp light source of taking pictures in described eyeground is incident to described perforate speculum after described illumination path first lens, described diffusion plate, described bright dipping diaphragm, described constraint diaphragm, described illumination path the 2nd lens, described stain plate, described illumination path the 3rd lens and described illumination diaphragm.
Further: described fundus camera also comprises optical system for alignment; Described optical system for alignment comprises: optical system for alignment module, the 4th spectroscope, described first spectroscope, described 2nd spectroscope, described in be embedded with the first perforate diaphragm perforate speculum, described in connect order object lens, receive lens, total reflective mirror, the 3rd spectroscope and described camera device; The two light beams that described optical system for alignment module sends is transmitted through the 2nd spectroscope through described 4th spectroscope part transmission, described first spectroscope successively, reflect through described 2nd spectroscope and inject people's eye by the first perforate diaphragm and the described order object lens that connect, described 4th spectroscope it is back to again after corneal reflex, reception lens are reflexed to through described 4th spectroscope part, reflexing to the 3rd spectroscope through total reflective mirror, described two-beam regulates through probe and just converges on camera device; Two hot spots coincided together that described camera device display two-beam produces because converging.
Further: described optical system for alignment module comprises: alignment light source, condensing lens, the 2nd perforate diaphragm, diplopore bright dipping diaphragm and be arranged between described 2nd perforate diaphragm and described diplopore diaphragm or at least one piece of optical system for alignment lens being arranged between described 2nd perforate diaphragm and described 4th spectroscope; Described alignment light source bright dipping by described 2nd perforate diaphragm, turns into described two light beams by described diplopore bright dipping diaphragm again after described condensing lens after described optical system for alignment lens, is then incident to described 4th spectroscope; Or after described diplopore bright dipping diaphragm, turn into described two light beams, then after described optical system for alignment lens, it is incident to described 4th spectroscope.
Further: described fundus camera also comprises note view display screen; What described note view display screen sent watches light attentively after the 3rd spectroscope reflects, then is incident to people's eye eyeground through described imaging lens, described tune after bending mirror, the 2nd spectroscope, the first perforate diaphragm and connecing order object lens successively; Wherein, described note view display screen and described camera device are relative to the 3rd spectroscope conjugation.
Further: described sample arm module also comprises Polarization Controller and light modulation journey assembly; Described light modulation journey assembly comprises described fiber device and sample arm light path focusing lens, and described Polarization Controller is adjacent with described fiber coupler, and described light modulation journey assembly and described eyeground OCT adjust mirror in the wrong adjacent.
Further: the wavelength of described OCT system source is the near infrared low-coherence light source of 800-880nm.
The technique effect of the present invention: the detection light sent due to OCT system source is being incident to people's eye eyeground and is being reflected back in fiber coupler process through people's eye eyeground, mirror is bent without the need to the tune through imaging optical path, therefore in scanning imagery process, can not adjust with light path and bend and affect the OCT signal light power on incident people's eye eyeground, thus realize the different good OCT tomoscan image bending light people's eye eyeground; In addition, owing to OCT module being fixedly installed relaying lens, ensure that conjugation near two-dimensional scan device and people's eye pupil, when two-dimensional scan device is scanned, detection light can through the first perforate diaphragm and people's eye pupil to be measured, ensure that detection optical center line converges at people's eye pupil to be measured, finally ensure that eyeground OCT image scope. In addition, adjust due to the eyeground OCT in OCT module the tune bent in mirror and imaging optical path to bend mirror and adopt coordinated signals mode, make the fiber device of sample arm and camera device all with people's eye eyeground conjugation, system only according to the sharpness of eyeground OCT preview image or the isoparametric judgement of strength of signal, need to be assisted and adjust the tune bending mirror and eyeground OCT tune mirror in the wrong to bend. Adjusting like this and bend, with the infrared preview imaging optical path in eyeground, Billy judges whether light path has adjusted dioptry, more objective, more accurate.
Accompanying drawing explanation
Fig. 1 is the system light path figure of the present invention;
Fig. 2 is the index path of OCT module 50 in Fig. 1;
In figure, each part sequence number and title are respectively:
100, illumination module;
101, eyeground photoflash lamp is taken pictures light source;
102, the infrared preview lighting source in eyeground;
103, lighting source spectroscope;
104, illumination path first lens;
105, diffusion plate;
106, bright dipping diaphragm;
107, diaphragm is retrained;
108, illumination path the 2nd lens;
109, stain plate;
110, illumination path the 3rd lens;
111, throw light on diaphragm;
201, order object lens are connect;
202, perforate speculum;
203, the first perforate diaphragm;
204, mirror in the wrong is adjusted;
205, imaging lens;
206, the 3rd spectroscope;
207, camera device;
30, optical system for alignment module;
301, alignment light source;
302, condensing lens;
303, the 2nd perforate diaphragm;
304, optical system for alignment lens;
305, diplopore bright dipping diaphragm;
306, the 4th spectroscope;
307, the 2nd spectroscope;
308, lens are received;
309, total reflective mirror;
401, view display screen is noted;
50, OCT module;
50A, sample arm module;
50B, reference arm module;
501, OCT system source;
502, fiber coupler;
503, Polarization Controller;
504, reference arm light Reuter mirror;
505, reference arm speculum;
506, detection system;
507, Controlling System;
508, sample arm light path focusing lens;
5080, light modulation journey assembly;
509, eyeground OCT adjusts and bends mirror;
510, two-dimensional scan device;
511, relaying lens;
512, the first spectroscope.
Embodiment
In order to make technical problem to be solved by this invention, technical scheme and useful effect clearly understand, below in conjunction with drawings and Examples, the present invention is further elaborated. It is to be understood that specific embodiment described herein is only in order to explain the present invention, it is not intended to limit the present invention.
With reference to figure 1 composition graphs 2, a kind of fundus camera in conjunction with OCT system of the present invention, comprise OCT module 50, first spectroscope 512, the 2nd spectroscope 307, first perforate diaphragm 203, connect order object lens 201 and imaging optical path and illumination path. Specifically, comprise with reference to figure 2, OCT module 50: OCT system source 501, fiber coupler 502, reference arm module 50B, detection system 506, Controlling System 507 and sample arm module 50A. Wherein, reference arm module 50B comprises reference arm light Reuter mirror 504 and reference arm speculum 505, and sample arm module 50A comprises the eyeground OCT arranged successively and adjusts mirror 509 in the wrong, two-dimensional scan device 510 and relaying lens 511. Relaying lens 511 are fixedly installed on the side of the first spectroscope 512. Eyeground OCT image light path principle of work is as follows: the light that OCT system source 501 exports respectively to sample arm module 50A offer detection light and provides reference light to reference arm module 50B through fiber coupler 502. Wherein, detection light through sample arm module 50A reflexes to the 2nd spectroscope 307 through the first spectroscope 512, after connecing order object lens 201, people eye E it is incident to again after the 2nd spectroscope 307 reflects and passes the first perforate diaphragm 203, it is back to the 2nd spectroscope 307 through connecing order object lens 201, first perforate diaphragm 203 again after eyeground Er reflects, reflex to the first spectroscope 512 through the 2nd spectroscope 307, then after sample arm module 50A, arrive fiber coupler 502; Reference light interferes at fiber coupler 502 with the detection light returned through sample arm module 50A after reference arm module 50B returns and obtains interference light, interference light is detected system 506 and detects, process through Controlling System 507, finally demonstrate the OCT image on eyeground. The illumination light that illumination path sends illuminates people's eye eyeground, is the offer lighting source of taking pictures of fundus camera. The imaging optical path of fundus camera comprises successively and connects order object lens 201, first perforate diaphragm 203, the 2nd spectroscope 307, imaging lens 205, adjusts and bend mirror 204, the 3rd spectroscope 206 and camera device 207. After illumination light is incident to people's eye eyeground, reflect through eyeground, successively through connecing order object lens 201, first perforate diaphragm 203, the 2nd spectroscope 307, imaging lens 205, adjust and bend mirror 204 and the 3rd spectroscope 206, final arrival camera device 207, camera device 207 is responsible for shooting people's eye eyeground and is shone. In imaging optical path, adjust and bend mirror 204 and can carry out the dioptry of different people eye adjusting and bend, ensure that eyeground conjugated image surface Er ' can with camera device 207 conjugation, thus obtain the clear picture on eyeground. In the present embodiment, imaging optical path is for the function of the infrared preview and white light flash photographing imaging that realize eyeground, and the infrared preview on eyeground and white light stroboscopic light sources see below the illumination path of description.
With reference to figure 2, further, sample arm module 50A also comprises Polarization Controller 503 and light modulation journey assembly 5080. Polarization Controller 503 is arranged near fiber coupler 502, and light modulation journey assembly 5080 adjusts mirror 509 in the wrong to arrange near eyeground OCT. Light modulation journey assembly 5080 comprises sample arm light path focusing lens 508 and sample arm fiber device (not shown). The detection light obtained through fiber coupler 502 light splitting is first regulated detection polarisation of light state by Polarization Controller 503, then by sample arm fiber device outgoing, after sample arm light path focusing lens 508, turn into collimation light, then it is incident to eyeground OCT and adjusts mirror 509 in the wrong.
By Fig. 1 and description above it may be seen that adjust and bend mirror 204 not in the light path of the detection light process of eyeground OCT image, therefore, eyeground OCT tomoscan is not adjusted, by the mirror 204 in the wrong of adjusting in imaging optical path, the impact bent. So to, in the scanning imagery process of eyeground, because of utilizing the OCT signal light power adjusted and bend mirror 204 tune and bend and affect incident people's eye eyeground, the stable of OCT signal light power can not being ensure that, thus realize the good OCT tomoscan image on different light people's eye eyeground in the wrong. In addition, owing to relaying lens 511 are fixedly installed near the first spectroscope 512, two-dimensional scan device 510 is conjugation near relaying lens 511 and the first perforate diaphragm 203, first perforate diaphragm 203 through connecing conjugation near order object lens 201 and people's eye pupil to be measured, i.e. conjugation near two-dimensional scan device 510 and people's eye pupil. When design makes two-dimensional scan device 510 scan like this, detection light through the first perforate diaphragm 203 and people's eye pupil to be measured, can ensure that detection optical center line converges at people's eye pupil to be measured. If relaying lens 511 can move to participate in adjusting and bend, the condition of conjugation near two-dimensional scan device 510 and people's eye pupil now just cannot be met. If system does not meet this conjugate relation, after relaying lens 511 move and participate in adjusting and bend, the first perforate diaphragm 203 or people's eye pupil can block the boundary scan light beam of detection light, thus limit the areas imaging of eyeground OCT.
When taking pictures, can select to be switched fast by fast goalkeeper the 3rd spectroscope 206, the 2nd spectroscope 307 to leave imaging optical path. Like this, just remaining by connecing order object lens 201, be embedded with the perforate speculum 202 of the first perforate diaphragm 203, adjust the new light path bent mirror 204, imaging lens 205 and camera device 207 and form. Mentioned here it is embedded, it is substantially that perforate speculum 202 is opened a hole, then the first perforate diaphragm 203 is embedded in this aperture. It is arranged so that imaging image planes illumination is symmetrical like this.
It should be noted that, it is the near infrared low-coherence light source that wavelength is preferably 800-880nm that the OCT system source 501 in the present invention exports.
With reference to figure 1, the illumination path in the technical program is by module 100 of throwing light on, the perforate speculum 202 being provided with the first perforate diaphragm 203 and connects order object lens 201 and forms. The light that illumination module 100 sends, through the reflection of perforate speculum 202, is then incident to people's eye through connecing order object lens 201; Through eyeground reflection, then it is incident to imaging optical path through connecing order object lens 201 and the first perforate diaphragm 203. The effect of illumination path is to provide illumination light for illuminating eyeground, and imaging optical path is then for taking people's eye eye fundus image. As a kind of enforcement mode specifically, illumination module 100 by eyeground photoflash lamp take pictures light source 101, the infrared preview lighting source 102 in eyeground, lighting source spectroscope 103, illumination path first lens 104, diffusion plate 105, bright dipping diaphragm 106, constraint diaphragm 107, illumination path the 2nd lens 108, stain plate 109, illumination path the 3rd lens 110 and illumination diaphragm 111 form. When using eyeground infrared preview lighting source 102, lighting source spectroscope 103 is inserted eyeground photoflash lamp and takes pictures in the light path between light source 101 and illumination path first lens 104, thus realize corresponding switching. Specifically, when after insertion lighting source spectroscope 103, close eyeground photoflash lamp to take pictures light source 101, now lighting source spectroscope 103 injected by the infrared preview lighting source 102 in eyeground, reflex to illumination path first lens 104 through lighting source spectroscope 103, and then after diffusion plate 105, bright dipping diaphragm 106, constraint diaphragm 107, illumination path the 2nd lens 108, stain plate 109, illumination path the 3rd lens 110 and illumination diaphragm 111, it is incident to perforate speculum 202 successively; Reflex to through perforate speculum 202 and connect order object lens 201, be then incident to people's eye through connecing order object lens 201; Through eyeground reflection, then arrive camera device 207 after connecing order object lens 201, first perforate diaphragm 203, the 2nd spectroscope 307, tune mirror 204 in the wrong, imaging lens 205 and the 3rd spectroscope 206 successively. When light source 101 taken pictures by use eyeground photoflash lamp, close the infrared preview lighting source 102 in eyeground, lighting source spectroscope 103 is withdrawn illumination module 100; Now photoflash lamp light source 101 of taking pictures in eyeground reflexes to through perforate speculum 202 and connects order object lens 201 after illumination path first lens 104, diffusion plate 105, bright dipping diaphragm 106, constraint diaphragm 107, illumination path the 2nd lens 108, stain plate 109, illumination path the 3rd lens 110 and illumination diaphragm 111 successively, through eyeground reflection, then arrive camera device 207 after connecing order object lens 201, first perforate diaphragm 203, the 2nd spectroscope 307, tune mirror 204 in the wrong, imaging lens 205 and the 3rd spectroscope 206 successively. Shooting people's eye eye fundus image is responsible for by camera device 207. It should be noted that, if lighting source spectroscope 103 adopts white light, when reflects infrared light designs, this spectroscope also still can be retained in illumination path at use eyeground photoflash lamp light source 101 of taking pictures.
With reference to figure 1, the fundus camera in conjunction with OCT in the technical program also comprises optical system for alignment, and this optical system for alignment comprises: optical system for alignment module 30, the 4th spectroscope 306, first spectroscope 512, the 2nd spectroscope 307, first perforate diaphragm 203, connects order object lens 201, receive lens 308, total reflective mirror 309, the 3rd spectroscope 206 and camera device 207. two light beams that optical system for alignment module 30 sends are transmitted through the 2nd spectroscope 307 through the 4th spectroscope 306 part transmission and the first spectroscope 512 successively, the first perforate diaphragm 203 is reflexed to through the 2nd spectroscope 307, then it is incident to people's eye through connecing order object lens 201, after corneal reflex again after connecing order object lens 201, through the first perforate diaphragm 203, it is incident to the 2nd spectroscope 307, it is transmitted through the 4th spectroscope 306 again through the first spectroscope 512, reflex to through the 4th spectroscope 306 part and receive lens 308, then the 3rd spectroscope 206 is reflexed to through total reflective mirror 309, reflect finally by the 3rd spectroscope 206, after the probe of adjustment ophthalmology OCT system, two-beam just converges on camera device 207, camera device 207 shows two hot spots coincided together that two light beams being gathered together produce, two two hot spots coincided together according to the observation, can judge that cornea summit is just positioned on the working position of fundus camera. specifically, optical system for alignment module 30 comprises the alignment light source 301, condensing lens 302, the 2nd perforate diaphragm 303, diplopore bright dipping diaphragm 305 and the optical system for alignment lens 304 that are arranged between the 2nd perforate diaphragm 303 and diplopore bright dipping diaphragm 305 or are arranged between diplopore bright dipping diaphragm 305 and the 4th spectroscope 306 that arrange successively. the light that alignment light source 301 sends turns into the two-beam described in this section through condensing lens 302, the 2nd perforate diaphragm 303, optical system for alignment lens 304 and diplopore bright dipping diaphragm 305 successively, and described two-beam is incident to the 4th spectroscope 306, or successively after condensing lens 302, the 2nd perforate diaphragm 303, then turn into being incident to after optical system for alignment lens 304 again after this section of described two-beam the 4th spectroscope 306 through diplopore bright dipping diaphragm 305. travel path after incident 4th spectroscope 306 of two light beams is just identical with this section travel path that part describes above. it should be noted that, in the technical program, said probe refers to and includes in Fig. 1 and Fig. 2 except the reference arm light Reuter mirror 504 included by system source 501, fiber coupler 502, Polarization Controller 503, detection system 506, Controlling System 507 and reference arm module 50B and all optical elements except reference arm speculum 505, these optical elements are built in a physical construction (not shown), in the process regulated integrally before and after, up and down, move left and right, so that the cornea summit Ec of people's eye is in the working position of fundus camera.
This fundus camera also comprises watches light path attentively. What the note view display screen 401 watching light path attentively sent watches light attentively after the 3rd spectroscope 206 reflects, it is incident to the 2nd spectroscope 307 successively again after imaging lens 205 and tune bend mirror 204, it is transmitted through the first perforate diaphragm 203 through the 2nd spectroscope 307, then it is incident to people eye E through connecing order object lens 201. Wherein, view display screen 401 is noted with camera device 207 relative to the 3rd spectroscope 206 conjugation. That is by adjust bend lens 204 movement so that when ophthalmology OCT system becomes fundus image the most clear, measured see watch attentively a little also the most clear. Be conducive to fixation, the eyeground preview of measured people's eye like this and take pictures.
In sum, in the present invention, what wherein the 3rd spectroscope 206 small portion reflection major part transmission note view display screen 401 sent watches light (being preferably green glow) attentively, the near infrared light that total reflection alignment light source 301 sends, the white light flash of light 101 of total transmissivity illumination module 100 outgoing and near infrared illumination 102. What the 2nd spectroscope 307 transmission note view display screen 401 sent watches light (green glow) attentively, the near infrared light that total reflection alignment light source 301 sends, the white light flash of light 101 of total transmissivity illumination module 100 outgoing and near infrared illumination 102.
The said fundus camera in conjunction with OCT system in the present invention, tool has the following advantages:
The first, system sample arm fiber device bright dipping, collimation light is turned into after the sample arm light path focusing lens 508 of light modulation journey assembly 5080, and the movement comprising the light modulation journey assembly 5080 of sample arm light path focusing lens 508 and sample arm fiber device (not shown) can not change detecting light beam focus state, but the light path of detection light can be changed.
Two, the two-dimensional scan device 510 of sample arm module 50A conjugation near relaying lens 511 and the first perforate diaphragm 203, first perforate diaphragm 203 through connecing conjugation near order object lens 201 and people's eye pupil to be measured, i.e. conjugation near two-dimensional scan device 510 and people's eye pupil to be measured. When design makes two-dimensional scan device 510 scan like this, light beam can through the first perforate diaphragm 203 and people's eye pupil to be measured. Can ensure that detecting light beam medullary ray converges at people's eye pupil to be measured. If relaying lens 511 can move to participate in adjusting and bend, the condition of conjugation near two-dimensional scan device 510 and people's eye pupil to be measured now just cannot be met. If system does not meet this conjugate relation, when relaying lens 511 move participate in adjust bend after, the first perforate diaphragm 203 or people's eye pupil can block the edge of detecting light beam, thus limit the areas imaging of eyeground OCT;
Three, insert eyeground OCT between light modulation journey assembly 5080 and two-dimensional scan device 510 and adjust mirror 509 in the wrong, eyeground OCT adjusts mirror 509 in the wrong to move along primary optical axis, do not change the conjugate relation of two-dimensional scan device 510 with people's eye pupil to be measured, but the focus state of OCT detecting light beam can be changed, it is thus possible to according to the dioptry of different people eye, allow the OCT detecting light beam of any time focus on people's eye eyeground to be measured.
Four, for the axis oculi length difference of different people eye, for realizing the coherent measurement of OCT system, reference arm is that module 50B maintains static, and now need to introduce light path regulation mechanism in sample arm light path. Specifically, native system adopts the scheme of spacing adjustable (concrete gearing structure is not shown) between sample arm light path light modulation journey assembly 5080 and two-dimensional scan device 510 of allowing, meet the needs of different people axis oculi length detection, namely adjust the position of light modulation journey assembly, thus change sample arm optical path length and realize.
The foregoing is only the better embodiment of the present invention, not in order to limit the present invention, all any amendment, equivalent replacement and improvement etc. done within the spirit and principles in the present invention, all should wrap within the scope of the present invention.
Claims (8)
1. in conjunction with a fundus camera for OCT system, comprising: OCT module, the first spectroscope, the 2nd spectroscope, be embedded with the perforate speculum of the first perforate diaphragm, connect order object lens, illumination path and imaging optical path; The light that the OCT system source of described OCT module sends obtains detection light and reference light through fiber coupler light splitting; Described detection light focuses on people's eye eyeground through the first spectroscope, the 2nd spectroscope, the first perforate diaphragm with after connecing order object lens successively after sample arm module, it is back to described fiber coupler after eyeground is reflected, and the reference light returned with the reference arm module being subordinated to described OCT module interferes at fiber coupler and forms interference light, interference light is detected system looks and arrives, through Controlling System process, the OCT image of display people's eye;
The illumination light that described illumination path sends is incident to people's eye eyeground, is incident to described imaging optical path after eyeground is reflected;
Described imaging optical path comprises: described in connect order object lens, described first perforate diaphragm, described 2nd spectroscope, adjust bend mirror, imaging lens, the 3rd spectroscope and camera device;
It is characterized in that: described sample arm module comprises relaying lens, two-dimensional scan device and eyeground OCT and adjusts mirror in the wrong, and described relaying lens are fixedly installed near described first spectroscope; Conjugation near described two-dimensional scan device and people's eye pupil; The fiber device of described camera device and described sample arm module all with people's eye eyeground conjugation.
2. as claimed in claim 1 in conjunction with the fundus camera of OCT system, it is characterised in that: described illumination path comprise illumination module, described in be embedded with the perforate speculum of the first perforate diaphragm and described connect order object lens; The illumination light that described illumination module sends connects order object lens and illuminates eyeground described in reflexing to through described perforate speculum.
3. as claimed in claim 2 in conjunction with the fundus camera of OCT system, it is characterised in that: described illumination module comprises: the infrared preview lighting source in eyeground, eyeground photoflash lamp take pictures light source, lighting source spectroscope, illumination path first lens, diffusion plate, bright dipping diaphragm, constraint diaphragm, illumination path the 2nd lens, stain plate, illumination path the 3rd lens and illumination diaphragm; The infrared preview in described eyeground lighting source, after described lighting source spectroscope reflects, is incident to described perforate speculum successively after described illumination path first lens, described diffusion plate, described bright dipping diaphragm, described constraint diaphragm, described illumination path the 2nd lens, described stain plate, described illumination path the 3rd lens and described illumination diaphragm; Or, photoflash lamp light source of taking pictures in described eyeground is incident to described perforate speculum after described illumination path first lens, described diffusion plate, described bright dipping diaphragm, described constraint diaphragm, described illumination path the 2nd lens, described stain plate, described illumination path the 3rd lens and described illumination diaphragm.
4. as claimed in claim 1 or 2 in conjunction with the fundus camera of OCT system, it is characterised in that: described fundus camera also comprises optical system for alignment; Described optical system for alignment comprises: optical system for alignment module, the 4th spectroscope, described first spectroscope, described 2nd spectroscope, described in be embedded with the first perforate diaphragm perforate speculum, described in connect order object lens, receive lens, total reflective mirror, the 3rd spectroscope and described camera device; The two-beam that described optical system for alignment module sends is transmitted through the 2nd spectroscope through described 4th spectroscope part transmission, described first spectroscope successively, reflect through described 2nd spectroscope and inject people's eye by the first perforate diaphragm and the described order object lens that connect, described 4th spectroscope it is back to again after corneal reflex, reception lens are reflexed to through described 4th spectroscope part, reflexing to the 3rd spectroscope through total reflective mirror, described two-beam regulates through probe and just converges on camera device; Two hot spots coincided together that described camera device display two-beam produces because converging.
5. as claimed in claim 4 in conjunction with the fundus camera of OCT system, it is characterised in that: described optical system for alignment module comprises: alignment light source, condensing lens, the 2nd perforate diaphragm, diplopore bright dipping diaphragm and be arranged between described 2nd perforate diaphragm and described diplopore diaphragm or at least one piece of optical system for alignment lens being arranged between described 2nd perforate diaphragm and described 4th spectroscope; Described alignment light source bright dipping by described 2nd perforate diaphragm, turns into described two-beam by described diplopore bright dipping diaphragm again after described condensing lens after described optical system for alignment lens, is then incident to described 4th spectroscope; Or after described diplopore bright dipping diaphragm, turn into described two-beam, then after described optical system for alignment lens, it is incident to described 4th spectroscope.
6. as claimed in claim 1 or 2 in conjunction with the fundus camera of OCT system, it is characterised in that: described fundus camera also comprises note view display screen; What described note view display screen sent watches light attentively after the 3rd spectroscope reflects, then is incident to people's eye eyeground through described imaging lens, described tune after bending mirror, the 2nd spectroscope, the first perforate diaphragm and connecing order object lens successively; Wherein, described note view display screen and described camera device are relative to the 3rd spectroscope conjugation.
7. as claimed in claim 1 or 2 in conjunction with the fundus camera of OCT system, it is characterised in that: described sample arm module also comprises Polarization Controller and light modulation journey assembly; Described light modulation journey assembly comprises described fiber device and sample arm light path focusing lens, and described Polarization Controller is adjacent with described fiber coupler, and described light modulation journey assembly and described eyeground OCT adjust mirror in the wrong adjacent.
8. as claimed in claim 1 or 2 in conjunction with the fundus camera of OCT system, it is characterised in that: described OCT system source is the near infrared low-coherence light source of wavelength 800-880nm.
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| CN112168132B (en) * | 2020-11-09 | 2022-11-08 | 苏州大学 | Method for performing fundus refraction compensation judgment and imaging optimization by using OCT (optical coherence tomography) signals |
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