CN104224109A - Fundus camera combined with OCT system - Google Patents
Fundus camera combined with OCT system Download PDFInfo
- Publication number
- CN104224109A CN104224109A CN201410550642.9A CN201410550642A CN104224109A CN 104224109 A CN104224109 A CN 104224109A CN 201410550642 A CN201410550642 A CN 201410550642A CN 104224109 A CN104224109 A CN 104224109A
- Authority
- CN
- China
- Prior art keywords
- spectroscope
- lens
- light
- diaphragm
- fundus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000005286 illumination Methods 0.000 claims abstract description 66
- 238000003384 imaging method Methods 0.000 claims abstract description 42
- 238000001514 detection method Methods 0.000 claims abstract description 22
- 230000003287 optical effect Effects 0.000 claims description 124
- 239000000523 sample Substances 0.000 claims description 36
- 238000007598 dipping method Methods 0.000 claims description 25
- 239000000835 fiber Substances 0.000 claims description 25
- 230000011514 reflex Effects 0.000 claims description 20
- 230000021615 conjugation Effects 0.000 claims description 18
- 210000001747 pupil Anatomy 0.000 claims description 17
- 230000010287 polarization Effects 0.000 claims description 8
- 230000005540 biological transmission Effects 0.000 claims description 5
- 230000026676 system process Effects 0.000 claims description 2
- 239000013307 optical fiber Substances 0.000 abstract description 2
- 235000005459 Digitaria exilis Nutrition 0.000 abstract 1
- 240000008570 Digitaria exilis Species 0.000 abstract 1
- 238000003325 tomography Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 description 10
- 230000008569 process Effects 0.000 description 6
- 238000005452 bending Methods 0.000 description 5
- 230000008859 change Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000001427 coherent effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000009415 formwork Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000005693 optoelectronics Effects 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000008844 regulatory mechanism Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
Abstract
The invention discloses a fundus camera combined with an OCT system. The fundus camera combined with the OCT system comprises an OCT module, a first spectroscope, a second spectroscope, a first trepanned diaphragm, an eye lens, an illumination light path and an imaging light path. The OCT model provides reference light and detecting light. The reference light returns after reflected through the fundus and generates interference with reference light returned from a reference arm module in an optical fiber coupler, interference light is detected by a detection system and processed through a control system, and an OCT image of the human eye is displayed. The illumination light path provides illumination light entering the fundus of the human eye, and the illumination light enters an imaging light path shooting human eye fundus images after being reflected by the fundus. According to the fundus camera combined with the OCT system, when tomography imaging is carried out on the fundus, the detecting light does not need to pass through a flexor adjusting lens of the imaging light path, the power of OCT signal light entering the human eye fundus cannot be influenced by flexor adjustment of the flexor adjusting lens, and therefore good OCT images of human eye fundi of different refractions can be obtained.
Description
Technical field
The present invention relates to optoelectronic areas, refer more particularly to a kind of fundus camera combining OCT system.
Background technology
Existing fundus camera, usually bend by the tune of imaging optical path the definition that mirror regulates infrared optical fundus preview image, or bend optical system for alignment to judge whether according to auxiliary tune and imaging optical path in the wrong for tune is adjusted to optimum state, and then taken pictures by ophthalmology OCT system execution flash lamp, obtain eye fundus image.But the definition of the eye fundus image obtained in this way is not high enough.In addition, application number is that disclosing of the patent application document of 200710302263.8 is a kind of by the technological means of the imaging optical path of OCT unit access fundus camera, and this method can improve the definition of eye fundus image.But, in that patent, also existing defects.With reference to Fig. 1 of the Figure of description of this patent and the 3rd section of reference description the 8th page.In FIG, the flashlight that OCT unit 150 sends is after connecting portion 151, again successively through hole portion 112a and the object lens 113 of lens 142, scanning element 141, dichroic mirror 134, capture lens 126, relay lens 125, variable power lens 124, shooting aperture 121, perforate eyeglass 112, be finally incident to human eye E.Can learn from above, flashlight needs can enter human eye E after the tune of variable power lens 124 (namely adjust and bend mirror) is bent.Therefore, in the OCT tomographic scanning procedure of optical fundus, the OCT signal light power that can affect and incide human eye optical fundus bent in the tune of variable power lens 124.
Summary of the invention
The invention provides a kind of fundus camera in conjunction with OCT system, its object is to solve and carrying out in OCT tomographic scanning procedure to optical fundus, affect the problem of the OCT signal light power on incident human eye optical fundus because light path tune is bent.
Technical scheme of the present invention is as follows:
In conjunction with a fundus camera for OCT system, comprising: OCT module, the first spectroscope, the second spectroscope, be embedded with the first perforate diaphragm perforate reflecting mirror, connect order object lens, illumination path and imaging optical path; The light that the OCT system source of described OCT module sends obtains detection light and reference light through fiber coupler light splitting; Described detection light after sample arm module successively through the first spectroscope, the second spectroscope, the first perforate diaphragm with focus on human eye optical fundus after connecing order object lens, described fiber coupler is back to after fundus reflex, and the reference light returned with the reference arm module being subordinated to described OCT module interferes at fiber coupler and forms interference light, interference light is detected system looks and arrives, through control system process, the OCT image of display human eye; The illumination light that described illumination path sends is incident to human eye optical fundus, is incident to described imaging optical path after fundus reflex; Described imaging optical path comprises: described in connect order object lens, described first perforate diaphragm, described second spectroscope, adjust bend mirror, imaging lens, the 3rd spectroscope and picture pick-up device; Described sample arm module comprises relay lens, two-dimensional scanner and optical fundus OCT and adjusts mirror in the wrong, and described relay lens is fixedly installed near described first spectroscope; Conjugation near described two-dimensional scanner and human eye pupil; The fiber device of described picture pick-up device and described sample arm module all with human eye optical fundus conjugation.
Further: described illumination path comprise lighting module, described in be embedded with the perforate reflecting mirror of the first perforate diaphragm and describedly connect order object lens; Connect order object lens described in the illumination light that described lighting module sends reflexes to through described perforate reflecting mirror and illuminate optical fundus.
Further: described lighting module comprises: the infrared preview lighting source in optical fundus, optical fundus flash lamp take pictures light source, lighting source spectroscope, illumination path first lens, diffusing panel, bright dipping diaphragm, about beam diaphragm, illumination path second lens, stain plate, illumination path the 3rd lens and illumination diaphragm; The infrared preview in described optical fundus lighting source, after described lighting source dichroic mirror, is incident to described perforate reflecting mirror successively after described illumination path first lens, described diffusing panel, described bright dipping diaphragm, described about beam diaphragm, described illumination path second lens, described stain plate, described illumination path the 3rd lens and described illumination diaphragm; Or flash lamp light source of taking pictures in described optical fundus is incident to described perforate reflecting mirror after described illumination path first lens, described diffusing panel, described bright dipping diaphragm, described about beam diaphragm, described illumination path second lens, described stain plate, described illumination path the 3rd lens and described illumination diaphragm.
Further: described fundus camera also comprises optical system for alignment; Described optical system for alignment comprises: optical system for alignment module, the 4th spectroscope, described first spectroscope, described second spectroscope, described in be embedded with the first perforate diaphragm perforate reflecting mirror, described in connect order object lens, receiver lens, total reflective mirror, the 3rd spectroscope and described picture pick-up device; The two light beams that described optical system for alignment module sends is transmitted through the second spectroscope through described 4th spectroscope fractional transmission, described first spectroscope successively, human eye is injected by the first perforate diaphragm and the described order object lens that connect through described second dichroic mirror, described 4th spectroscope is back to again after corneal reflex, receiver lens is reflexed to through described 4th spectroscope part, reflex to the 3rd spectroscope through total reflective mirror, described two-beam regulates through probe and just converges on picture pick-up device; Described picture pick-up device display two-beam is because converging two hot spots coincided together produced.
Further: described optical system for alignment module comprises: alignment light source, collecting lens, the second perforate diaphragm, diplopore bright dipping diaphragm and be arranged between described second perforate diaphragm and described diplopore diaphragm or be arranged at least one block alignment light path lens between described second perforate diaphragm and described 4th spectroscope; Described alignment light source bright dipping by described second perforate diaphragm, becomes described two light beams by described diplopore bright dipping diaphragm again after described collecting lens after described optical system for alignment lens, is then incident to described 4th spectroscope; Or after described diplopore bright dipping diaphragm, become described two light beams, then after described optical system for alignment lens, be incident to described 4th spectroscope.
Further: described fundus camera also comprises point of fixation display screen; What described point of fixation display screen sent watches light attentively after the 3rd dichroic mirror, then bends mirror, the second spectroscope, the first perforate diaphragm through described imaging lens, described tune and be incident to human eye optical fundus after connecing order object lens successively; Wherein, described point of fixation display screen and described picture pick-up device are relative to the 3rd spectroscope conjugation.
Further: described sample arm module also comprises Polarization Controller and light modulation journey assembly; Described light modulation journey assembly comprises described fiber device and sample arm light path focusing lens, and described Polarization Controller is adjacent with described fiber coupler, and described light modulation journey assembly and described optical fundus OCT adjust mirror in the wrong adjacent.
Further: the wavelength of described OCT system source is the near-infrared low-coherence light source of 800-880nm.
Technique effect of the present invention: the detection light sent due to OCT system source is being incident to human eye optical fundus and in human eye fundus reflex back into optical fibers bonder process, mirror is bent without the need to the tune through imaging optical path, therefore in scanning imagery process, can not bend with light path tune and affect the OCT signal light power on incident human eye optical fundus, thus realize the good OCT tomoscan image on different dioptric human eye optical fundus; In addition, owing to being fixedly installed relay lens in OCT module, ensure that conjugation near two-dimensional scanner and human eye pupil, when two-dimensional scanner is scanned, detection light can through the first perforate diaphragm and human eye pupil to be measured, ensure that detection light center line converges at human eye pupil to be measured, finally ensure that optical fundus OCT areas imaging.In addition, coordinated signals mode is adopted because the optical fundus OCT in OCT module adjusts the tune of bending in mirror and imaging optical path to bend mirror, make the fiber device of sample arm and picture pick-up device all with human eye optical fundus conjugation, system only according to the definition of optical fundus OCT preview image or the isoparametric judgement of signal intensity, need be assisted and adjust mirror in the wrong and optical fundus OCT to adjust the tune of bending mirror to bend.Such tune is bent, and with the infrared preview imaging optical path in optical fundus, Billy judges whether light path mixes up diopter, more objective, more accurate.
Accompanying drawing explanation
Fig. 1 is system light path figure of the present invention;
Fig. 2 is the index path of OCT module 50 in Fig. 1;
In figure, each part sequence number and title are respectively:
100, lighting module;
101, optical fundus flash lamp is taken pictures light source;
102, the infrared preview lighting source in optical fundus;
103, lighting source spectroscope;
104, illumination path first lens;
105, diffusing panel;
106, bright dipping diaphragm;
107, about beam diaphragm;
108, illumination path second lens;
109, stain plate;
110, illumination path the 3rd lens;
111, throw light on diaphragm;
201, order object lens are connect;
202, perforate reflecting mirror;
203, the first perforate diaphragm;
204, mirror in the wrong is adjusted;
205, imaging lens;
206, the 3rd spectroscope;
207, picture pick-up device;
30, optical system for alignment module;
301, alignment light source;
302, collecting lens;
303, the second perforate diaphragm;
304, optical system for alignment lens;
305, diplopore bright dipping diaphragm;
306, the 4th spectroscope;
307, the second spectroscope;
308, receiver lens;
309, total reflective mirror;
401, point of fixation display screen;
50, OCT module;
50A, sample arm module;
50B, reference arm module;
501, OCT system source;
502, fiber coupler;
503, Polarization Controller;
504, reference arm light Reuter mirror;
505, reference arm reflecting mirror;
506, detection system;
507, control system;
508, sample arm light path focusing lens;
5080, light modulation journey assembly;
509, optical fundus OCT adjusts and bends mirror;
510, two-dimensional scanner;
511, relay lens;
512, the first spectroscope.
Detailed description of the invention
In order to make technical problem to be solved by this invention, technical scheme and beneficial effect clearly understand, below in conjunction with drawings and Examples, the present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
With reference to figure 1 composition graphs 2, a kind of fundus camera in conjunction with OCT system of the present invention, comprise OCT module 50, first spectroscope 512, second spectroscope 307, first perforate diaphragm 203, connect order object lens 201 and imaging optical path and illumination path.Particularly, comprise with reference to figure 2, OCT module 50: OCT system source 501, fiber coupler 502, reference arm module 50B, detection system 506, control system 507 and sample arm module 50A.Wherein, reference arm module 50B comprises reference arm light Reuter mirror 504 and reference arm reflecting mirror 505, and sample arm module 50A comprises the optical fundus OCT set gradually and adjusts mirror 509, two-dimensional scanner 510 and relay lens 511 in the wrong.Relay lens 511 is fixedly installed on the side of the first spectroscope 512.Optical fundus OCT imaging optical path operation principle is as follows: the light that OCT system source 501 exports provides detection light and provide reference light to reference arm module 50B through fiber coupler 502 respectively to sample arm module 50A.Wherein, detection light through sample arm module 50A reflexes to the second spectroscope 307 through the first spectroscope 512, after connecing order object lens 201, human eye E is incident to again after the second spectroscope 307 reflects and passes the first perforate diaphragm 203, the second spectroscope 307 is back to through connecing order object lens 201, first perforate diaphragm 203 again after optical fundus Er reflects, reflex to the first spectroscope 512 through the second spectroscope 307, then arrive fiber coupler 502 after sample arm module 50A; Reference light interferes at fiber coupler 502 with the detection light returned through sample arm module 50A and obtains interference light after reference arm module 50B returns, interference light is detected system 506 and detects, process through control system 507, finally demonstrate the OCT image on optical fundus.The illumination light that illumination path sends illuminates human eye optical fundus, for taking pictures of fundus camera provides lighting source.The imaging optical path of fundus camera comprise successively connect order object lens 201, first perforate diaphragm 203, second spectroscope 307, imaging lens 205, adjust bend mirror 204, the 3rd spectroscope 206 and picture pick-up device 207.After illumination light is incident to human eye optical fundus, through fundus reflex, successively through connecing order object lens 201, first perforate diaphragm 203, second spectroscope 307, imaging lens 205, adjusting and bend mirror 204 and the 3rd spectroscope 206, final arrival picture pick-up device 207, picture pick-up device 207 is responsible for shooting human eye optical fundus and is shone.In imaging optical path, adjust and bend mirror 204 to carry out to the diopter of different human eye tunes in the wrong, ensure that optical fundus conjugated image surface Er ' can with picture pick-up device 207 conjugation, thus obtain the sharply defined image on optical fundus.In the present embodiment, imaging optical path is for the function of the infrared preview and the imaging of white light flash photographing that realize optical fundus, and the infrared preview on optical fundus and white light stroboscopic light sources see below the illumination path of description.
With reference to figure 2, further, sample arm module 50A also comprises Polarization Controller 503 and light modulation journey assembly 5080.Polarization Controller 503 is arranged near fiber coupler 502, and light modulation journey assembly 5080 adjusts mirror 509 in the wrong to arrange near optical fundus OCT.Light modulation journey assembly 5080 comprises sample arm light path focusing lens 508 and sample arm fiber device (not shown).The detection light obtained through fiber coupler 502 light splitting is first polarized controller 503 adjustment detection polarisation of light state, then by the outgoing of sample arm fiber device, after sample arm light path focusing lens 508, become collimated light, be then incident to optical fundus OCT and adjust mirror 509 in the wrong.
As can be seen from Fig. 1 and description above, adjust and bend mirror 204 not in the light path of the detection light process of optical fundus OCT imaging, therefore, by the tune in imaging optical path, mirror 204 is not bent to optical fundus OCT tomoscan and adjusts the impact of bending.So in the scanning imagery process of optical fundus, the OCT signal light power on incident human eye optical fundus can not be affected because of utilizing tune mirror 204 tune in the wrong to bend, ensure that the stable of OCT signal light power, thus realizing the good OCT tomoscan image on different dioptric human eye optical fundus.In addition, because relay lens 511 is fixedly installed near the first spectroscope 512, two-dimensional scanner 510 is conjugation near relay lens 511 and the first perforate diaphragm 203, first perforate diaphragm 203 through connecing conjugation near order object lens 201 and human eye pupil to be measured, i.e. conjugation near two-dimensional scanner 510 and human eye pupil.When such design makes two-dimensional scanner 510 scan, detection light through the first perforate diaphragm 203 and human eye pupil to be measured, can ensure that detection light center line converges at human eye pupil to be measured.If relay lens 511 can move to participate in adjusting and bend, the condition of conjugation near two-dimensional scanner 510 and human eye pupil now just cannot be met.If system does not meet this conjugate relation, when relay lens 511 move participate in adjust bend after, the first perforate diaphragm 203 or human eye pupil can block detection light boundary scan light beam, thus restriction optical fundus OCT areas imaging.
When taking pictures, can select to be switched fast by fast goalkeeper the 3rd spectroscope 206, second spectroscope 307 to leave imaging optical path.Like this, just remaining by connecing order object lens 201, being embedded with the perforate reflecting mirror 202 of the first perforate diaphragm 203, adjusting the new light path of bending mirror 204, imaging lens 205 and picture pick-up device 207 and forming.Mentioned herely to be embedded, to be in fact that perforate reflecting mirror 202 is opened a hole, then the first perforate diaphragm 203 to be embedded in this aperture.Be arranged so that imaging illuminance of image plane is symmetrical like this.
It should be noted that, it is the near-infrared low-coherence light source that wavelength is preferably 800-880nm that the OCT system source 501 in the present invention exports.
With reference to figure 1, the illumination path in the technical program by lighting module 100, be provided with the first perforate diaphragm 203 perforate reflecting mirror 202 and connect order object lens 201 and form.The light that lighting module 100 sends, through the reflection of perforate reflecting mirror 202, is then incident to human eye through connecing order object lens 201; Through fundus reflex, then through connecing order object lens 201 and the first perforate diaphragm 203 is incident to imaging optical path.The effect of illumination path is to provide illumination light for illuminating optical fundus, and imaging optical path is then for taking human eye eye fundus image.As a kind of concrete embodiment, lighting module 100 by optical fundus flash lamp take pictures light source 101, the infrared preview lighting source 102 in optical fundus, lighting source spectroscope 103, illumination path first lens 104, diffusing panel 105, bright dipping diaphragm 106, about beam diaphragm 107, illumination path second lens 108, stain plate 109, illumination path the 3rd lens 110 and illumination diaphragm 111 form.When using optical fundus infrared preview lighting source 102, lighting source spectroscope 103 being inserted in light path that optical fundus flash lamp takes pictures between light source 101 and illumination path first lens 104, thus realizing corresponding switching.Particularly, when after insertion lighting source spectroscope 103, close optical fundus flash lamp to take pictures light source 101, now lighting source spectroscope 103 injected by the infrared preview lighting source 102 in optical fundus, reflex to illumination path first lens 104 through lighting source spectroscope 103, and then after diffusing panel 105, bright dipping diaphragm 106, about beam diaphragm 107, illumination path second lens 108, stain plate 109, illumination path the 3rd lens 110 and illumination diaphragm 111, be incident to perforate reflecting mirror 202 successively; Reflexing to through perforate reflecting mirror 202 and connect order object lens 201, being then incident to human eye through connecing order object lens 201; Through fundus reflex, then arrive picture pick-up device 207 after connecing order object lens 201, first perforate diaphragm 203, second spectroscope 307, tune mirror 204, imaging lens 205 and the 3rd spectroscope 206 in the wrong successively.When use optical fundus flash lamp takes pictures light source 101, close the infrared preview lighting source 102 in optical fundus, lighting source spectroscope 103 is withdrawn lighting module 100; Now flash lamp light source 101 of taking pictures in optical fundus reflexes to through perforate reflecting mirror 202 and connects order object lens 201 successively after illumination path first lens 104, diffusing panel 105, bright dipping diaphragm 106, about beam diaphragm 107, illumination path second lens 108, stain plate 109, illumination path the 3rd lens 110 and illumination diaphragm 111, through fundus reflex, then arrive picture pick-up device 207 after connecing order object lens 201, first perforate diaphragm 203, second spectroscope 307, tune mirror 204, imaging lens 205 and the 3rd spectroscope 206 in the wrong successively.Shooting human eye eye fundus image is responsible for by picture pick-up device 207.It should be noted that, if lighting source spectroscope 103 adopts white light, during reflects infrared light design, this spectroscope also still can be retained in illumination path at use optical fundus flash lamp light source 101 of taking pictures.
With reference to figure 1, the fundus camera in conjunction with OCT in the technical program also comprises optical system for alignment, and this optical system for alignment comprises: optical system for alignment module 30, the 4th spectroscope 306, first spectroscope 512, second spectroscope 307, first perforate diaphragm 203, connect order object lens 201, receiver lens 308, total reflective mirror 309, the 3rd spectroscope 206 and picture pick-up device 207.Two light beams that optical system for alignment module 30 sends are transmitted through the second spectroscope 307 through the 4th spectroscope 306 fractional transmission and the first spectroscope 512 successively, the first perforate diaphragm 203 is reflexed to through the second spectroscope 307, then human eye is incident to through connecing order object lens 201, after corneal reflex again after connecing order object lens 201, through the first perforate diaphragm 203, be incident to the second spectroscope 307, the 4th spectroscope 306 is transmitted through again through the first spectroscope 512, receiver lens 308 is reflexed to through the 4th spectroscope 306 part, then the 3rd spectroscope 206 is reflexed to through total reflective mirror 309, reflect finally by the 3rd spectroscope 206, after probe by adjustment ophthalmology OCT system, two-beam just converges on picture pick-up device 207, picture pick-up device 207 shows two hot spots coincided together of the two light beams generations be gathered together, two two hot spots coincided together according to the observation, can judge that corneal vertex is just positioned on the operating position of fundus camera.Particularly, optical system for alignment module 30 comprises the alignment light source 301, collecting lens 302, second perforate diaphragm 303, the diplopore bright dipping diaphragm 305 that set gradually and is arranged between the second perforate diaphragm 303 and diplopore bright dipping diaphragm 305 or is arranged on the optical system for alignment lens 304 between diplopore bright dipping diaphragm 305 and the 4th spectroscope 306.The light that alignment light source 301 sends becomes the two-beam described in this section through collecting lens 302, second perforate diaphragm 303, optical system for alignment lens 304 and diplopore bright dipping diaphragm 305 successively, and described two-beam is incident to the 4th spectroscope 306; Or successively after collecting lens 302, second perforate diaphragm 303, then become after this section of described two-beam through diplopore bright dipping diaphragm 305 and after optical system for alignment lens 304, be incident to the 4th spectroscope 306 again.Propagation path after incident 4th spectroscope 306 of two light beams is just identical with the propagation path that this section of previous section describes.It should be noted that, in the technical program, said probe refers to and includes in Fig. 1 and Fig. 2 except the reference arm light Reuter mirror 504 included by system source 501, fiber coupler 502, Polarization Controller 503, detection system 506, control system 507 and reference arm module 50B and all optical elements except reference arm reflecting mirror 505, these optical elements are built in a frame for movement (not shown), in the process regulated integrally before and after, up and down, move left and right, with the operating position making the corneal vertex Ec of human eye be in fundus camera.
This fundus camera also comprises watches light path attentively.What the point of fixation display screen 401 watching light path attentively sent watches light attentively after the 3rd spectroscope 206 reflects, the second spectroscope 307 is incident to successively again through imaging lens 205 with after adjusting mirror 204 in the wrong, being transmitted through the first perforate diaphragm 203 through the second spectroscope 307, being then incident to human eye E through connecing order object lens 201.Wherein, point of fixation display screen 401 and picture pick-up device 207 are relative to the 3rd spectroscope 206 conjugation.That is by adjusting the movement of bending lens 204, when making ophthalmology OCT system become fundus image the most clear, measured sees that point of fixation is also the most clear.Be conducive to the fixation of measured's human eye, optical fundus preview like this and take pictures.
In sum, in the present invention, what wherein the 3rd spectroscope 206 fraction reflect most transmission point of fixation display screen 401 sent watches light (being preferably green glow) attentively, the near infrared light that total reflection alignment light source 301 sends, the white light flash of light 101 of total transmissivity illumination formwork 100 outgoing and near infrared illumination 102.What the second spectroscope 307 transmission point of fixation display screen 401 sent watches light (green glow) attentively, the near infrared light that total reflection alignment light source 301 sends, the white light flash of light 101 of total transmissivity lighting module 100 outgoing and near infrared illumination 102.
The said fundus camera in conjunction with OCT system in the present invention, tool has the following advantages:
The first, system sample arm fiber device bright dipping, collimated light is become after the sample arm light path focusing lens 508 of light modulation journey assembly 5080, and the movement comprising the light modulation journey assembly 5080 of sample arm light path focusing lens 508 and sample arm fiber device (not shown) can not change detecting light beam focus state, but the light path of detection light can be changed.
The second, the two-dimensional scanner 510 of sample arm module 50A conjugation near relay lens 511 and the first perforate diaphragm 203, first perforate diaphragm 203 through connecing conjugation near order object lens 201 and human eye pupil to be measured, i.e. conjugation near two-dimensional scanner 510 and human eye pupil to be measured.When such design makes two-dimensional scanner 510 scan, light beam can through the first perforate diaphragm 203 and human eye pupil to be measured.Can ensure that detecting light beam centrage converges at human eye pupil to be measured.If relay lens 511 can move to participate in adjusting and bend, the condition of conjugation near two-dimensional scanner 510 and human eye pupil to be measured now just cannot be met.If system does not meet this conjugate relation, when relay lens 511 move participate in adjust bend after, the first perforate diaphragm 203 or human eye pupil can block the edge of detecting light beam, thus restriction optical fundus OCT areas imaging;
Three, insert optical fundus OCT between light modulation journey assembly 5080 and two-dimensional scanner 510 and adjust mirror 509 in the wrong, optical fundus OCT adjusts mirror 509 in the wrong to move along primary optical axis, do not change two-dimensional scanner 510 and the oculopupillary conjugate relation of people to be measured, but the focus state of OCT detecting light beam can be changed, thus can, according to the diopter of different human eye, allow the OCT detecting light beam of any time focus on human eye optical fundus to be measured.
Four, the axis oculi for different human eye is long different, and for realizing the coherent measurement of OCT system, reference arm is that module 50B maintains static, and now need introduce light path regulatory mechanism in sample arm light path.Particularly, native system adopts the scheme of the spacing between sample arm light path light modulation journey assembly 5080 and two-dimensional scanner 510 adjustable (concrete gearing structure is not shown) of allowing, meet the needs of the long detection of different people axis oculi, namely adjust the position of light modulation journey assembly, thus change sample arm optical path length realizes.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should wrap within the scope of the present invention.
Claims (8)
1., in conjunction with a fundus camera for OCT system, comprising: OCT module, the first spectroscope, the second spectroscope, be embedded with the first perforate diaphragm perforate reflecting mirror, connect order object lens, illumination path and imaging optical path; The light that the OCT system source of described OCT module sends obtains detection light and reference light through fiber coupler light splitting; Described detection light after sample arm module successively through the first spectroscope, the second spectroscope, the first perforate diaphragm with focus on human eye optical fundus after connecing order object lens, described fiber coupler is back to after fundus reflex, and the reference light returned with the reference arm module being subordinated to described OCT module interferes at fiber coupler and forms interference light, interference light is detected system looks and arrives, through control system process, the OCT image of display human eye; The illumination light that described illumination path sends is incident to human eye optical fundus, is incident to described imaging optical path after fundus reflex; Described imaging optical path comprises: described in connect order object lens, described first perforate diaphragm, described second spectroscope, adjust bend mirror, imaging lens, the 3rd spectroscope and picture pick-up device; It is characterized in that: described sample arm module comprises relay lens, two-dimensional scanner and optical fundus OCT and adjusts mirror in the wrong, and described relay lens is fixedly installed near described first spectroscope; Conjugation near described two-dimensional scanner and human eye pupil; The fiber device of described picture pick-up device and described sample arm module all with human eye optical fundus conjugation.
2., as claimed in claim 1 in conjunction with the fundus camera of OCT system, it is characterized in that: described illumination path comprise lighting module, described in be embedded with the perforate reflecting mirror of the first perforate diaphragm and describedly connect order object lens; Connect order object lens described in the illumination light that described lighting module sends reflexes to through described perforate reflecting mirror and illuminate optical fundus.
3. as claimed in claim 2 in conjunction with the fundus camera of OCT system, it is characterized in that: described lighting module comprises: the infrared preview lighting source in optical fundus, optical fundus flash lamp take pictures light source, lighting source spectroscope, illumination path first lens, diffusing panel, bright dipping diaphragm, about beam diaphragm, illumination path second lens, stain plate, illumination path the 3rd lens and illumination diaphragm; The infrared preview in described optical fundus lighting source, after described lighting source dichroic mirror, is incident to described perforate reflecting mirror successively after described illumination path first lens, described diffusing panel, described bright dipping diaphragm, described about beam diaphragm, described illumination path second lens, described stain plate, described illumination path the 3rd lens and described illumination diaphragm; Or flash lamp light source of taking pictures in described optical fundus is incident to described perforate reflecting mirror after described illumination path first lens, described diffusing panel, described bright dipping diaphragm, described about beam diaphragm, described illumination path second lens, described stain plate, described illumination path the 3rd lens and described illumination diaphragm.
4. as claimed in claim 1 or 2 in conjunction with the fundus camera of OCT system, it is characterized in that: described fundus camera also comprises optical system for alignment; Described optical system for alignment comprises: optical system for alignment module, the 4th spectroscope, described first spectroscope, described second spectroscope, described in be embedded with the first perforate diaphragm perforate reflecting mirror, described in connect order object lens, receiver lens, total reflective mirror, the 3rd spectroscope and described picture pick-up device; The two light beams that described optical system for alignment module sends is transmitted through the second spectroscope through described 4th spectroscope fractional transmission, described first spectroscope successively, human eye is injected by the first perforate diaphragm and the described order object lens that connect through described second dichroic mirror, described 4th spectroscope is back to again after corneal reflex, receiver lens is reflexed to through described 4th spectroscope part, reflex to the 3rd spectroscope through total reflective mirror, described two-beam regulates through probe and just converges on picture pick-up device; Described picture pick-up device display two-beam is because converging two hot spots coincided together produced.
5. as claimed in claim 4 in conjunction with the fundus camera of OCT system, it is characterized in that: described optical system for alignment module comprises: alignment light source, collecting lens, the second perforate diaphragm, diplopore bright dipping diaphragm and be arranged between described second perforate diaphragm and described diplopore diaphragm or be arranged at least one block alignment light path lens between described second perforate diaphragm and described 4th spectroscope; Described alignment light source bright dipping by described second perforate diaphragm, becomes described two light beams by described diplopore bright dipping diaphragm again after described collecting lens after described optical system for alignment lens, is then incident to described 4th spectroscope; Or after described diplopore bright dipping diaphragm, become described two light beams, then after described optical system for alignment lens, be incident to described 4th spectroscope.
6. as claimed in claim 1 or 2 in conjunction with the fundus camera of OCT system, it is characterized in that: described fundus camera also comprises point of fixation display screen; What described point of fixation display screen sent watches light attentively after the 3rd dichroic mirror, then bends mirror, the second spectroscope, the first perforate diaphragm through described imaging lens, described tune and be incident to human eye optical fundus after connecing order object lens successively; Wherein, described point of fixation display screen and described picture pick-up device are relative to the 3rd spectroscope conjugation.
7. as claimed in claim 1 or 2 in conjunction with the fundus camera of OCT system, it is characterized in that: described sample arm module also comprises Polarization Controller and light modulation journey assembly; Described light modulation journey assembly comprises described fiber device and sample arm light path focusing lens, and described Polarization Controller is adjacent with described fiber coupler, and described light modulation journey assembly and described optical fundus OCT adjust mirror in the wrong adjacent.
8. as claimed in claim 1 or 2 in conjunction with the fundus camera of OCT system, it is characterized in that: the wavelength of described OCT system source is the near-infrared low-coherence light source of 800-880nm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410550642.9A CN104224109B (en) | 2014-10-16 | 2014-10-16 | A kind of fundus camera in conjunction with OCT system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410550642.9A CN104224109B (en) | 2014-10-16 | 2014-10-16 | A kind of fundus camera in conjunction with OCT system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN104224109A true CN104224109A (en) | 2014-12-24 |
| CN104224109B CN104224109B (en) | 2016-06-08 |
Family
ID=52213668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410550642.9A Active CN104224109B (en) | 2014-10-16 | 2014-10-16 | A kind of fundus camera in conjunction with OCT system |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104224109B (en) |
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147250A (en) * | 2015-08-19 | 2015-12-16 | 苏州塞罗尔医学影像科技有限公司 | Portable optical coherent chromatography imaging device |
| CN106073698A (en) * | 2016-06-14 | 2016-11-09 | 江苏大学 | A kind of fundus imaging method based on Android |
| CN107260120A (en) * | 2017-05-31 | 2017-10-20 | 执鼎医疗科技（杭州）有限公司 | A kind of camera and the common light path imaging devices of OCT |
| CN109242893A (en) * | 2018-08-23 | 2019-01-18 | 深圳市斯尔顿科技有限公司 | Imaging method, method for registering images and device |
| CN109998471A (en) * | 2019-01-28 | 2019-07-12 | 执鼎医疗科技（杭州）有限公司 | A kind of OCT system that reference arm is fixed |
| CN110522406A (en) * | 2019-08-16 | 2019-12-03 | 广州浩康生物科技有限公司 | A kind of apparatus for measuring ocular axial length and axiallength measurement method |
| CN110584591A (en) * | 2019-09-03 | 2019-12-20 | 佛山科学技术学院 | High-precision portable diopter detector |
| CN110793918A (en) * | 2019-11-13 | 2020-02-14 | 深圳市斯尔顿科技有限公司 | Industrial OCT detection device and method based on spatial free distribution light path |
| CN111035358A (en) * | 2019-12-28 | 2020-04-21 | 重庆贝奥新视野医疗设备有限公司 | Stray light eliminating system of fundus camera and working method thereof |
| CN112168132A (en) * | 2020-11-09 | 2021-01-05 | 苏州大学 | Method for performing fundus refraction compensation judgment and imaging optimization by using OCT (optical coherence tomography) signals |
| CN113331782A (en) * | 2021-07-13 | 2021-09-03 | 宁波明星科技发展有限公司 | Computer optometry unit |
| CN113509142A (en) * | 2021-06-07 | 2021-10-19 | 天津市索维电子技术有限公司 | Large-visual-field retina examination device |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100014052A1 (en) * | 2006-12-21 | 2010-01-21 | Ingo Koschmieder | Optical system for a fundus camera |
| CN102438505A (en) * | 2011-04-23 | 2012-05-02 | 深圳市斯尔顿科技有限公司 | Ophthalmology oct system and ophthalmology imaging method |
| CN102824161A (en) * | 2012-09-13 | 2012-12-19 | 深圳市斯尔顿科技有限公司 | Ophthalmologic OCT (Optical Coherence Tomography) system and ophthalmologic OCT imaging method |
| CN103799974A (en) * | 2012-11-09 | 2014-05-21 | 佳能株式会社 | Ophthalmologic apparatus and control method |
| CN203643682U (en) * | 2012-04-24 | 2014-06-11 | 深圳市斯尔顿科技有限公司 | Ophthalmic optical coherence tomography system |
| CN103976707A (en) * | 2014-05-20 | 2014-08-13 | 深圳市斯尔顿科技有限公司 | OCT (Optical Coherence Tomography) system for measuring optical path value of axis oculi and method |
| CN204105944U (en) * | 2014-10-16 | 2015-01-21 | 深圳市斯尔顿科技有限公司 | A kind of fundus camera in conjunction with OCT system |
-
2014
- 2014-10-16 CN CN201410550642.9A patent/CN104224109B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100014052A1 (en) * | 2006-12-21 | 2010-01-21 | Ingo Koschmieder | Optical system for a fundus camera |
| CN102438505A (en) * | 2011-04-23 | 2012-05-02 | 深圳市斯尔顿科技有限公司 | Ophthalmology oct system and ophthalmology imaging method |
| CN203643682U (en) * | 2012-04-24 | 2014-06-11 | 深圳市斯尔顿科技有限公司 | Ophthalmic optical coherence tomography system |
| CN102824161A (en) * | 2012-09-13 | 2012-12-19 | 深圳市斯尔顿科技有限公司 | Ophthalmologic OCT (Optical Coherence Tomography) system and ophthalmologic OCT imaging method |
| CN103799974A (en) * | 2012-11-09 | 2014-05-21 | 佳能株式会社 | Ophthalmologic apparatus and control method |
| CN103976707A (en) * | 2014-05-20 | 2014-08-13 | 深圳市斯尔顿科技有限公司 | OCT (Optical Coherence Tomography) system for measuring optical path value of axis oculi and method |
| CN204105944U (en) * | 2014-10-16 | 2015-01-21 | 深圳市斯尔顿科技有限公司 | A kind of fundus camera in conjunction with OCT system |
Cited By (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147250A (en) * | 2015-08-19 | 2015-12-16 | 苏州塞罗尔医学影像科技有限公司 | Portable optical coherent chromatography imaging device |
| CN106073698A (en) * | 2016-06-14 | 2016-11-09 | 江苏大学 | A kind of fundus imaging method based on Android |
| CN107260120A (en) * | 2017-05-31 | 2017-10-20 | 执鼎医疗科技（杭州）有限公司 | A kind of camera and the common light path imaging devices of OCT |
| CN109242893B (en) * | 2018-08-23 | 2020-09-04 | 深圳市斯尔顿科技有限公司 | Imaging method, image registration method and device |
| CN109242893A (en) * | 2018-08-23 | 2019-01-18 | 深圳市斯尔顿科技有限公司 | Imaging method, method for registering images and device |
| CN109998471A (en) * | 2019-01-28 | 2019-07-12 | 执鼎医疗科技（杭州）有限公司 | A kind of OCT system that reference arm is fixed |
| CN110522406A (en) * | 2019-08-16 | 2019-12-03 | 广州浩康生物科技有限公司 | A kind of apparatus for measuring ocular axial length and axiallength measurement method |
| CN110584591A (en) * | 2019-09-03 | 2019-12-20 | 佛山科学技术学院 | High-precision portable diopter detector |
| CN110793918A (en) * | 2019-11-13 | 2020-02-14 | 深圳市斯尔顿科技有限公司 | Industrial OCT detection device and method based on spatial free distribution light path |
| CN111035358A (en) * | 2019-12-28 | 2020-04-21 | 重庆贝奥新视野医疗设备有限公司 | Stray light eliminating system of fundus camera and working method thereof |
| CN112168132A (en) * | 2020-11-09 | 2021-01-05 | 苏州大学 | Method for performing fundus refraction compensation judgment and imaging optimization by using OCT (optical coherence tomography) signals |
| CN112168132B (en) * | 2020-11-09 | 2022-11-08 | 苏州大学 | Method for performing fundus refraction compensation judgment and imaging optimization by using OCT (optical coherence tomography) signals |
| CN113509142A (en) * | 2021-06-07 | 2021-10-19 | 天津市索维电子技术有限公司 | Large-visual-field retina examination device |
| CN113509142B (en) * | 2021-06-07 | 2023-06-02 | 天津市索维电子技术有限公司 | Large-vision retina examination device |
| CN113331782A (en) * | 2021-07-13 | 2021-09-03 | 宁波明星科技发展有限公司 | Computer optometry unit |
| CN113331782B (en) * | 2021-07-13 | 2024-03-22 | 宁波明星科技发展有限公司 | Computer optometry instrument |
Also Published As
| Publication number | Publication date |
|---|---|
| CN104224109B (en) | 2016-06-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104224109A (en) | Fundus camera combined with OCT system | |
| CN101040776B (en) | A fundus observation device | |
| CN101268928B (en) | Fundus oculi observation device and ophthalmic image display device | |
| JP5545629B2 (en) | Ophthalmic imaging equipment | |
| US8308297B2 (en) | Connection adapter, optical tomographic imaging apparatus, program for executing imaging method and memory device for the program | |
| JP2009261438A5 (en) | ||
| JP2001512994A (en) | Ophthalmoscope that laser scans a wide field of view | |
| US9687143B2 (en) | Ophthalmic photography device, ophthalmic photography method, and ophthalmic photography program | |
| CN104257347B (en) | The fundus camera optical system that human eye operating position is aimed at and position aligning method | |
| CN104939803B (en) | Ophthalmologic imaging method and imaging apparatus | |
| CN204105944U (en) | A kind of fundus camera in conjunction with OCT system | |
| CN108852617A (en) | A kind of ophthalmic operating microscope system | |
| CN108577802A (en) | In conjunction with the ophthalmic operating microscope system of OCT image | |
| CN204158362U (en) | For the auxiliary tune dioptric road of imaging optical path in fundus camera | |
| JP6173169B2 (en) | Ophthalmic apparatus and method for controlling ophthalmic apparatus | |
| KR20140016168A (en) | Ophthalmologic apparatus and ophthalmologic method | |
| WO2019138916A1 (en) | Fundus imaging device | |
| JP2000005131A (en) | Fundus camera | |
| JPH0646995A (en) | Eye refractometer | |
| WO2016189890A1 (en) | Ophthalmologic imaging apparatus | |
| CN103795916A (en) | Imaging apparatus and focusing method for imaging apparatus | |
| JP2019118720A (en) | Ophthalmography device | |
| JP4080183B2 (en) | Anterior segment imaging device | |
| JP2021062162A (en) | Scanning type ocular fundus imaging apparatus | |
| JP6916011B2 (en) | Ophthalmic equipment |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address |
Address after: 518000 803, block B, Jingang center, Jingang building, houye community, Xixiang street, Bao'an District, Shenzhen, Guangdong Patentee after: Shenzhen moting Medical Technology Co.,Ltd. Address before: 518112 Room 601, No. 3, Juyin technology industrial plant, No. 1, Ganli Road, gankeng community, Buji street, Longgang District, Shenzhen, Guangdong Patentee before: SHENZHEN CERTAINN TECHNOLOGY Co.,Ltd. |
|
| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: Room L302, Building 2, Skyworth Innovation Valley, No. 8 Tangtou 1st Road, Tangtou Community, Shiyan Street, Bao'an District, Shenzhen City, Guangdong Province, 518108 Patentee after: Shenzhen Moting Medical Technology Co.,Ltd. Address before: 518000 803, block B, Jingang center, Jingang building, houye community, Xixiang street, Bao'an District, Shenzhen, Guangdong Patentee before: Shenzhen moting Medical Technology Co.,Ltd. |
|
| CP03 | Change of name, title or address |