CN103674840B - Debug the method for cartridge calibration scan device and debug cartridge and system - Google Patents
Debug the method for cartridge calibration scan device and debug cartridge and system Download PDFInfo
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- CN103674840B CN103674840B CN201310578808.3A CN201310578808A CN103674840B CN 103674840 B CN103674840 B CN 103674840B CN 201310578808 A CN201310578808 A CN 201310578808A CN 103674840 B CN103674840 B CN 103674840B
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Abstract
The invention belongs to photoelectricity field, disclose a kind of method utilizing debugging cartridge calibration scan device, comprise the calibration of X-direction sweep unit and/or Y-direction scan components is calibrated.To X-direction scanned copy: X-direction scanned copy scanning raised item, the OCT faulted scanning pattern of the section of OCT imaging system acquires raised item, and with the center position X1 of calibration for benchmark, the physical scan area center line of X-direction scanned copy is overlapped with light path primary optical axis; To Y-direction scan components, comprising: the second Y-direction scanned copy coordinates the first Y-direction scanned copy scanning raised item, and the section of OCT imaging system acquires raised item also forms OCT tomoscan picture group; Determine the accurate scan center Y22 of the second Y-direction scanned copy; Then determine the accurate scan center Y11 of the first Y-direction scanned copy, Y-direction scanning area center line is overlapped with the primary optical axis of described light path.This method makes scanister calibration process simple, quick, and adjustment accuracy is high.
Description
Technical field
The invention belongs to photoelectricity field, be related specifically to a kind of system utilizing the method for debugging cartridge calibration scan device and debugging cartridge and include this debugging cylinder.
Background technology
For OCT system, when carrying out scanning imagery to sample, multiple technologies can be adopted to realize scanning process, as galvanometer rotary scanning, driven by motor rotation sweep or by certain physical construction and adopt stepper motor drive realize scanning.No matter adopting which kind of Scan Architecture device, when carrying out light path center adjustment, adopting artificial judgment more, whether light path aligns, center whether contraposition.But when artificial judgment regulates, exist not objectively shortcoming more, accurately cannot carry out center contraposition.And operation often needs repeatedly constantly to test, and could determine the rotation center position of scanister.This point is for light path commissioning engineer, and regulation scheme is convenient, fast not and objective.
And after shell loaded onto by instrument, light path is all closed in the enclosure.Once find light path not timing, often adopt after taking shell apart and carry out optical path adjusting.This adjustment work needs the professional customer service slip-stick artist of producer to operate more.Thus, for user, light path calibration work more cannot realize voluntarily.
Summary of the invention
The invention provides a kind of utilize debugging cylinder debugging scanister method, debugging cartridge and by debugging cylinder be used in debugging light path on system, be intended to solve in the process of debugging scanister X-direction scanned copy and Y-direction scan components, the problem that the scanning area center line of X-direction scanned copy and the scanning area center line of Y-direction scan components cannot overlap with system light path primary optical axis.
Technical scheme of the present invention is such:
The method of debugging cartridge calibration scan device, comprises and calibrates the X-direction scanned copy of described scanister and/or calibrate Y-direction scan components;
Described calibration X-direction scanned copy comprises:
Raised item in described X-direction scanned copy scanning debugging cartridge; one OCT faulted scanning pattern of raised item described in OCT imaging system acquires, the center position X1 of the described X-direction scanned copy that the first row pixel L0 at one article of seamed edge line place of raised item described in an OCT faulted scanning pattern is corresponding described in computer-made decision;
The center position X1 of described X-direction scanned copy is set to its center of rotation parameter by computing machine; Described X-direction scanned copy rotates with described center position X1 scanning, and its physical scan area center line is overlapped with the primary optical axis of light path;
Described to the calibration of Y-direction scan components, comprising:
Define described Y-direction scan components and comprise the first Y-direction scanned copy and/or the second Y-direction scanned copy;
If described Y-direction scan components comprises the first Y-direction scanned copy and the second Y-direction scanned copy, then:
Described second Y-direction scanned copy scans described raised item, determines its accurate scan center Y22, and the physical scan area center line of described second Y-direction scanned copy is overlapped with the primary optical axis of light path;
Described first Y-direction scanned copy scans described raised item with preliminary sweep center of rotation Y10, determine its accurate scan center Y11, and scan rotation with described accurate scan center Y11, the physical scan area center line of described first Y-direction scanned copy is overlapped with the primary optical axis of light path;
If described Y-direction scan components only includes the first Y-direction scanned copy or only includes the second Y-direction scanned copy, then:
Described to the first Y-direction scanned copy or the second Y-direction scanned copy calibration steps identical with to described X-direction scanned copy calibration steps.
Further: the defining method of the center position X1 of described X-direction scanned copy is: according to formula
Wherein, N is an OCT faulted scanning pattern Width pixel count, N1 is the pixel count between the first row pixel L0 at the centre line L 1 of an OCT faulted scanning pattern and one article of seamed edge line place of raised item, X0 is the initial rotation center of X-direction scanned copy, Xmax is the X-direction scanister scanning total angle of rotation, and X1 is the center position after the calibration of X-direction scanned copy; N, X0, Xmax are systemic presupposition data, and N1 is drawn by computer calculate, just can obtain X1 by above formula.
Further: scan the raised item in described debugging cartridge at described X-direction scanned copy, the OCT faulted scanning pattern of raised item described in OCT imaging system acquires, before the center position X1 step of the described X-direction scanned copy that the first row pixel L0 at a seamed edge line place of OCT faulted scanning pattern protrusions bar is corresponding described in computer-made decision, also comprise:
Debugging cartridge, probe light path system and OCT imaging system is set gradually according to light path; Described probe light path system comprises described X-direction scanned copy and described Y-direction scan components.
Further: describedly set gradually debugging cartridge according to light path, specifically comprise:
Described raised item be placed on debugging cylinder bottom inside and a wherein seamed edge line of described raised item is given prominence to towards described debugging cylinder bottom inside, making described raised item just meet system beam coherence distance to the distance of described probe light path system simultaneously;
When to described X-direction scanned copy calibration debugging, described seamed edge line all keeps vertical with the rotation axis of described X-direction scanned copy and the rotation axis of described first Y-direction scanned copy; When to described Y-direction scan components calibration debugging, the rotation axis of described seamed edge line and described first Y-direction scanned copy and/or the equal keeping parallelism of turning axle of the second Y-direction scanned copy;
Debugging cylinder lens, pressure Jing Quan are successively set in debugging cylinder inside circumference, and the position making the through hole on described pressure Jing Quan just and the position consistency of the convergent point of scanning light beam center line.
Further: described to X-direction scanned copy calibration steps before, also comprise:
Described first Y-direction scanned copy is gone to its rotation center position Y10 and/or the rotating mechanism of described second Y-direction scanned copy is gone to its rotation center Y20.
Further: described to Y-direction scan components calibration steps before, the described calibration to X-direction scanned copy can also be comprised; Described to X-direction scanned copy calibration steps before, the described calibration to Y-direction scan components can also be comprised.
Further: described second Y-direction scanned copy scans described raised item, determine that in the Y22 of its accurate scan center, described scanning is accurate scan after first coarse scan, comprising:
Second Y-direction scanned copy slowly scans described raised item with larger or less rotation stepping angle;
One OCT tomoscan picture group of raised item described in described OCT imaging system acquires;
The width figure that in a described OCT tomoscan picture group, overall signal is the strongest found out by computing machine, determines that described second Y-direction scanned copy roughly scans center position Y21;
Described second Y-direction scanned copy coordinates the first Y-direction scanned copy to described raised item fine scanning with the described center position Y21 that roughly scans;
Described OCT imaging system gathers the 2nd OCT tomoscan picture group of described raised item again;
The sequence number of the width figure that overall signal is the strongest in described 2nd OCT tomoscan picture group found out by computing machine, determines the accurate scan center Y22 of the second Y-direction scanned copy.
Further: described first Y-direction scanned copy scans described raised item with preliminary sweep center of rotation Y10, determine its accurate scan center Y11, the step that the physical scan area center line of described first Y-direction scanned copy is overlapped with the primary optical axis of light path is:
Described first Y-direction scanned copy scans described raised item with preliminary sweep center of rotation Y10;
2nd OCT faulted scanning pattern of raised item described in OCT imaging system acquires;
The accurate scan center Y11 of the corresponding described first Y-direction scanned copy of secondary series pixel L0 ' at one article of seamed edge line place of the 2nd OCT faulted scanning pattern protrusions described in computer-made decision article;
The accurate scan center Y11 of the first Y-direction scanned copy is set to the center of rotation parameter of the first Y-direction scanned copy by computing machine, described first Y-direction scanned copy scans with described accurate scan center Y11 and rotates, and the physical scan area center line of described first Y-direction scanned copy is overlapped with the primary optical axis of light path.
Further: the method that the width figure that overall signal is the strongest in a described OCT tomoscan picture group or the 2nd OCT tomoscan picture group found out by computing machine is:
When light beam is incident along primary optical axis, through described raised item surface reflection and the turned position of the second Y-direction scanned copy the closer to its accurate scan center Y22 time, the image of OCT imaging system acquires is a width figure the strongest in a described OCT tomoscan picture group or the 2nd OCT tomoscan picture group.
Further: the accurate scan center Y22 of described second Y-direction scanned copy, the roughly scanning center position Y21 of the second Y-direction scanned copy are identical with the defining method of the accurate scan center Y11 of the first Y-direction scanned copy defining method that is equal and the described center position X1 to X-direction scanned copy.
A kind of debugging cartridge, comprising: the debugging cylinder of hollow and be arranged on the raised item of its bottom inside, along a crest line of described raised item to projecting inward; Described raised item meets system beam coherence distance just to the distance of described probe light path system.
Further: also comprise and be arranged on debugging cylinder lens on inside described debugging cylinder and pressure Jing Quan from inside to outside; The through hole passed through for light source is offered in the middle of described pressure mirror circle; The position of described through hole just and the position consistency of the convergent point of scanning light beam center line.
Further: the section perpendicular to a crest line of described raised item is at least the one of V-arrangement, triangle or arch.
Debug a system for scanister, comprising: the debugging cartridge set gradually according to light path, probe light path system and OCT imaging system, described probe light path system comprises: X-direction scanned copy and/or Y-direction scan components.
Further: described Y-direction scan components comprises the first Y-direction scanned copy and/or the second Y-direction scanned copy.
Beneficial effect of the present invention: the raised item of X-direction scanned copy scanning debugging cartridge, one OCT faulted scanning pattern of OCT imaging system acquires raised item section, judges the center position X1 of the corresponding described X-direction scanned copy of the first row pixel L0 at a described OCT faulted scanning pattern protrusions article place, summit; X-direction scanned copy with center position X1 scanning, thus makes its physical scan area center line overlap with the primary optical axis of light path;
Y-direction scan components comprises the first Y-direction scanned copy and/or the second Y-direction scanned copy; If comprise the first Y-direction scanned copy and the second Y-direction scanned copy, then debugging cartridge to the calibration steps of Y-direction scan components is: the second Y-direction scanned copy coordinates the first Y-direction scanned copy first to raised item coarse scanning, first tomoscan picture group of OCT imaging system acquires raised item, the signal of the width figure that computer-made decision overall signal is the strongest, determines the second Y-direction scanned copy roughly scanning center position Y21; Second Y-direction scanned copy coordinates the first Y-direction scanned copy to the scanning of raised item essence again, second tomoscan picture group of OCT imaging system acquires raised item, judge the signal of the width figure that overall signal is the strongest, determine the second Y-direction scanned copy accurate scan center Y22, the physical scan area center line of the second Y-direction scanned copy is overlapped with the primary optical axis of light path; The basis that first Y-direction scanned copy confirms at the accurate scan angle of the second Y-direction scanned copy is scanned raised item again, now determine the accurate scan center Y11 of the first Y-direction scanned copy, with determining that its sector scanning center line is identical with light path primary optical axis coincidence method to X-direction scanned copy, complete the calibration to Y-direction scan components and debugging; If Y scan components only includes the first Y-direction scanned copy or the second Y-direction scanned copy, then utilize the method for debugging cylinder to its physical scan area center line calibration identical with to the calibration steps of X-direction scanned copy.
Therefore, utilize the debugging X-direction scanned copy of cartridge to scanister and/or the adjustment of Y-direction scan components, following effect being realized: 1, without the need to taking shell apart, just can realize the calibration to them, thus make debugging efforts simple, quick; 2, debug process is simple, even if the personnel not possessing professional knowledge utilize the method and equipment debugging scanister, also can debug out satisfied result.
Accompanying drawing explanation
Fig. 1 is the process flow diagram that debugging cartridge is debugged X-direction scanned copy;
Fig. 2 is the process flow diagram that debugging cartridge is debugged the Y-direction scan components including the first Y-direction scanned copy and the second Y-direction scanned copy;
Fig. 3 is the particular flow sheet of step S202 in Fig. 2;
Fig. 4 is system light path figure of the present invention;
Fig. 5 is the inner structure schematic diagram of the debugging cartridge 300 in Fig. 4;
Fig. 6 is along the view that A-A analyses and observe in Fig. 4;
Fig. 7 debugs cartridge not depart from the RC schematic diagram of OCT image to raised item before X-direction scanned copy, the debugging of Y-direction scan components in the present invention;
Fig. 8 debugs cartridge to be in the RC schematic diagram of OCT image to raised item after X-direction scanned copy, the debugging of Y-direction scan components in the present invention.
Fig. 9 is the schematic perspective view of raised item.
Figure 10 is the situation that the scanning area center line of the first Y-direction scanned copy 202 and the scanning area center line of the second Y-direction scanned copy 204 all overlap with system light path primary optical axis.
Figure 11 is that the scanning area center line of the first Y-direction scanned copy 202 and system light path primary optical axis do not overlap but the situation that overlaps of the scanning area center line of the second Y-direction scanned copy 204 and system light path primary optical axis.
Figure 12 is that the scanning area center line of the first Y-direction scanned copy 202 and the scanning area center line of the second Y-direction scanned copy 204 are all got along well the situation of position of system light path primary optical axis.
Wherein, in Fig. 4 and Fig. 5, the part name of each part sequence number and correspondence is respectively: 100, OCT imaging system; 200, probe light path system; 201, X-direction scanned copy; 202, the first Y-direction scanned copy; 204, the second Y-direction scanned copy; 300, cartridge is debugged; 301, cylinder is debugged; 301 ', the imaging of cylinder bottom inside in OCT image is debugged; 302, Jing Quan is pressed; 3021, through hole; 303, cylinder lens are debugged; 304, raised item; 3041, seamed edge line; 304 ', the imaging of raised item 304 in OCT image; 3041 ', seamed edge line 3041 imaging in OCT image.
Embodiment
In order to make technical matters to be solved by this invention, technical scheme and beneficial effect clearly understand, below in conjunction with drawings and Examples, the present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
embodiment 1: to the calibration of X-direction scanned copy 201
With reference to figure 1 and Fig. 6, the process of the calibration of debugging cartridge 300 pairs of X-direction scanned copies 201 is as follows:
Step S102: the raised item in described X-direction scanned copy scanning debugging cartridge; one OCT faulted scanning pattern of raised item described in OCT imaging system acquires, the center position X1 of the corresponding described X-direction scanned copy of first row pixel L0 at one article of seamed edge line place of an OCT faulted scanning pattern protrusions described in computer-made decision article;
Particularly, when X-direction scanned copy 201 scans the raised item in debugging cartridge, OCT imaging system 100 scans raised item 304, obtains an OCT faulted scanning pattern.When X-direction scanned copy is in a certain position, OCT imaging system 100 gathers the image of a line of raised item 304.When X-direction scanned copy forwards the next position to, OCT imaging system 100 gathers the image of another line of raised item 304 again.So repeatedly, X-direction scanned copy forwards one-period to, and OCT imaging system 100 just collects the image of the complete width OCT faulted scanning pattern of raised item 304.
For the determination of the center position X1 of X-direction scanned copy in this step; accomplished in many ways can be had; the technical program only illustrates the embodiment realizing its object, but for realizing the technical scheme of same object with other means, also belongs to the row of the protection domain of present patent application.
With reference to figure 7, one OCT faulted scanning pattern Width pixel count is N, the X-direction vibration mirror scanning total angle of rotation is Xmax, the center line of image is L1, one article of seamed edge line 3041(of raised item 304 is shown in Fig. 9) imaging 3041 ' in an OCT faulted scanning pattern, L0 is the row pixel through 3041 ' place, the initial rotation center of X-direction scanned copy 201 is in X0 ' in the drawings. as seen from Figure 7, center of rotation after the calibration of X0 ' and X-direction scanned copy 201 position X1 ' does not in the drawings overlap, and the center position X1 after calibration is the center position of system, this center position makes X-direction scanning area center line overlap with system primary optical axis.The object that debugging cartridge 300 calibrates X-direction scanned copy 201 is exactly to make initial rotation center X0 be calibrated to X1 position.If the pixel count in an OCT faulted scanning pattern between X1 and X0 is N1, Xmax is the X-direction vibration mirror scanning total angle of rotation.Wherein N, X0, Xmax are systemic presupposition data, and N1 is drawn by computer calculate, according to formula
obtain
thus determine the center position X1 of X-direction scanned copy 201, then enter step S103.
Step S103: the center position X1 of described X-direction scanned copy is set to the center of rotation parameter of described X-direction scanned copy by computing machine; Described X-direction scanned copy rotates with described center position X1 scanning, and its physical scan area center line is overlapped with the primary optical axis of light path.。
Particularly, after X-direction scanned copy 201 determines its center position X1, it is as reference rotational, obtains image as shown in Figure 8, and namely the physical scan area centre line L 1 of the OCT faulted scanning pattern of raised item 304 and the primary optical axis L2(of light path system are shown in Fig. 8, Fig. 4) overlap.That is, the rotation center of X-direction scanned copy 201 has been calibrated.
With reference to figure 4, before calibrating with debugging cartridge 300 pairs of X-direction scanned copies 201, also comprise step S101: set gradually debugging cartridge 300, probe light path system 200 and OCT imaging system 100 according to light path.Wherein, light path system 200 of popping one's head in includes X-direction scanned copy 201 and Y-direction scan components.Y-direction scan components comprises the first Y-direction scanned copy 202 and/or the second Y-direction scanned copy 204, and that is, Y-direction scan components can only include the first Y-direction scanned copy 202, also can only include the second Y-direction scanned copy 204; The first Y-direction scanned copy 202 and the second Y-direction scanned copy 204 can also be comprised simultaneously.What Fig. 4 showed is the situation simultaneously comprising the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204, and the situation only including the first Y-direction scanned copy 202 or the second Y-direction scanned copy 204 is not shown.
Before step S101, namely before X-direction scanned copy 201 being carried out to adjustment calibration, also need to carry out following steps:
Described Y-direction scan components is rotated to its rotation center position;
Particularly, described first Y-direction scanned copy 202 is gone to its rotation center position Y10 and/or the rotating mechanism of the second Y-direction scanned copy 204 is gone to its rotation center Y20, this is because Y-direction scan components comprises the situation having the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204 and only include the first Y-direction scanned copy 202 or the second Y-direction scanned copy 204 simultaneously.
Before to X-direction scanned copy calibration steps, can also comprise the described calibration to Y-direction scan components, can not certainly calibrate Y-direction scan components, this does not affect calibrates X-direction scanned copy.
When the first Y-direction scanned copy 202 being gone to rotation center position Y10 and/or the second Y-direction scanned copy 204 being gone to rotation center position Y20, now no matter whether Y10 and/or Y20 is strictly in design attitude, and the debug results of debugging cartridge 300 pairs of X-direction scanned copies 201 does not have an impact.Even if the rotating mechanism of the first Y-direction scanned copy 202 and/or the second Y-direction scanned copy 204 there occurs " drift ", debugging cartridge 300 also can calibrate the center null position of X-direction scanned copy 201.
When debugging X-direction scanned copy with debugging cartridge 300, the through hole 3021(of pressure mirror circle 302 of debugging cartridge 300 is shown in Fig. 5) position just and the position consistency of the convergent point of scanning light beam center line, raised item 304 meets system beam coherence distance, to meet the needs of OCT to raised item 304 scanning imagery just with the distance of probe light path system 200.
With reference to figure 5, Fig. 6 and Fig. 9, in the process utilizing debugging cartridge 300 pairs of X-direction scanned copies 201 to calibrate, raised item 304 need be arranged in the plane of debugging cartridge 300 bottom inside.Raised item 304 is designed to strip.When raised item 304 being arranged on debugging cartridge 300 bottom inside, must ensure that the wherein seamed edge line 3041 along it is given prominence to towards debugging cartridge 300 bottom inside, the object done like this is to ensure that scanning light beam can scan from the nearest seamed edge line of raised item 304.Should ensure that raised item 304 meets the requirement of system beam coherence distance, to meet OCT imaging needs to the distance of probe light path system 200 simultaneously.
Particularly, the shape perpendicular to the section of a seamed edge line 3041 of raised item 304 can be all passable apparently higher than the figure on other limits for triangle (see Fig. 6, Fig. 9), V-arrangement and its seamed edge every.In addition, in the process utilizing debugging cartridge 300 pairs of X-direction scanned copies 201 to calibrate, the seamed edge line (such as seamed edge line 3041) of raised item 304 is vertical with the rotation axis of X-direction scanned copy 201, simultaneously also vertical with the rotation axis of the first Y-direction scanned copy 202.
Because debugging cartridge 300 protrusions bar 304 adopts stripe design, even if this design makes the preliminary sweep center of rotation Y20 of the preliminary sweep center of rotation Y10 of the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204 slightly depart from, but when OCT imaging system 100 pairs of raised items 304 carry out X-direction scanning imagery, gained OCT faultage image can not change.Therefore, in the preamble, when judging the center position X1 of X-direction scanned copy 201, the rotation center Y10 of the first Y-direction scanned copy 202 and rotation center Y20 of the second Y-direction scanned copy 204 departs from slightly, has nothing to do to the calibration of scanning center's parameter of X-direction scanned copy 201.
Debugging cartridge 300 can be calibrated X-direction scanned copy 201.In addition, it can also to Y-direction scan components calibration debugging.That is, debugging cartridge 300 not only can be calibrated X-direction scanned copy 201, also can calibrate Y-direction scan components; Both individually to X-direction scanned copy 201 and the calibration of Y-direction scan components, also can first can calibrate Y-direction scan components after X-direction scanned copy 201.
As previously mentioned, Y-direction scan components comprises the first Y-direction scanned copy 202 and/or the second Y-direction scanned copy 204.
In addition, debugging cartridge 300 is before the calibration of the rotating mechanism to the first Y-direction scanned copy 202 and/or the second Y-direction scanned copy 204, to the calibration of X-direction scanned copy 201, certainly, also can also can not comprise the calibration of debugging cartridge 300 pairs of X-direction scanned copies 201.These two kinds of results are on the calibration of the rotating mechanism of the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204 not impact.
embodiment 2:the calibration of debugging cartridge 300 pairs of Y-direction scan components, now Y-direction scan components comprises the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204.
With reference to figures 10 to Figure 12.Figure 10 is the situation that the scanning area center line of the first Y-direction scanned copy 202 and the scanning area center line of the second Y-direction scanned copy 204 all overlap with system light path primary optical axis.This kind of situation is optimal situation, also be that debugging cartridge 300 debugs the object that Y-direction scan components (comprising the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204) wishes to reach, now without the need to calibrating the scanning center of the first Y-direction scanned copy 202 and scanning center's debugging of the second Y-direction scanned copy 204.Figure 11 is that the scanning area center line of the first Y-direction scanned copy 202 and system light path primary optical axis do not overlap but the situation that overlaps of the scanning area center line of the second Y-direction scanned copy 204 and system light path primary optical axis, in this case, illuminating source still can focus on the O point on system primary optical axis.The through hole 3021(of pressure mirror circle 302 that wherein O point is debugging cartridge 300 is shown in Fig. 5) center, and O point just with the position consistency of the convergent point of the scanning light beam center line envisioned.Be that the scanning area center line of the first Y-direction scanned copy 202 and the scanning area center line of the second Y-direction scanned copy 204 are all got along well the situation of position of system light path primary optical axis with reference to Figure 12, Figure 12.Now, the focal spot of illuminating source is in P point, and P point is not on system primary optical axis, namely P point is not in the center of the through hole 3021 of the pressure mirror circle 302 of debugging cartridge 300, now light beam can be blocked by through hole 3021 and full incidence cannot debug cartridge 300, causes the signal weaker of the OCT image of the raised item of gained.By to the scanning center of the first Y-direction scanned copy 202 and scanning center's calibration of the second Y-direction scanned copy 204, their physical scan area center line is overlapped with system light path primary optical axis, reaches the effect the same with Figure 10.The object to the calibration of Y-direction scan components described by this patent is exactly mainly the situation for Figure 12, namely needs simultaneously to the scanning center of the first Y-direction scanned copy 202 and scanning center's calibration of the second Y-direction scanned copy 204.
Utilize the calibration of the rotating mechanism of debugging cartridge 300 pairs of Y-direction scan components, slightly different compared with the calibration steps of X-direction scanned copy 201.
Known by light path principle, light beam through the minute surface foveal reflex of X-direction scanned copy 201 behind the minute surface center of the first Y-direction scanned copy 202, light beam is through the mirror-reflection of the first Y-direction scanned copy 202, through relay lens 203, after the reflection of the second Y-direction scanned copy 204, if light beam can continue the central axis along system light path design, then the rotational angle of the rotating mechanism of the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204 is unique, and can determine.By the known calibration adopting debugging cartridge 300 just can realize the rotating mechanism to the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204 of this principle.
Before the calibration of the rotating mechanism to the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204, also need to perform following steps:
Allow X-direction scanned copy 201 go to rotation center X0, and keep motionless; If X-direction carries out scan calibration, X-direction scanned copy center position X1 can be gone to;
The raised item 304 of debugging cartridge 300 is arranged to the equal keeping parallelism of turning axle with the rotation axis of the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204.
Further, before the calibration of the rotating mechanism to the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204, also the position of the through hole of the pressure mirror circle 302 of debugging cartridge 300 is needed to be arranged to just and the position consistency of the convergent point of scanning light beam center line, raised item 304 still meets system beam coherence distance, to meet the needs of OCT to raised item scanning imagery just with the distance of probe.Requirement when this point and debugging cartridge 300 pairs of X-direction scanned copies 201 are calibrated is identical.
Lower mask body sets forth the calibration process of debugging cartridge 300 to the rotating mechanism of the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204.
With reference to figure 2 also composition graphs 4, debugging cartridge 300 pairs of Y-direction scan components calibration process concrete steps are as follows:
S201: the part defining described Y-direction scan components is respectively the first Y-direction scanned copy and the second Y-direction scanned copy;
S202: described second Y-direction scanned copy scans described raised item, determines its accurate scan center Y22, and the physical scan area center line of described second Y-direction scanned copy is overlapped with the primary optical axis of light path;
S203: described first Y-direction scanned copy scans described raised item with preliminary sweep center of rotation Y10, determines its accurate scan center Y11, and the physical scan area center line of described first Y-direction scanned copy is overlapped with the primary optical axis of light path;
Particularly, for S201, the object done like this is the meaning in order to more clearly express present patent application file in the following description, and therefore, artificial is the first Y-direction scanned copy and the second Y-direction scanned copy by the Part Definition of Y-direction scan components.
Particularly, for S202, the accurate scan mode that can realize the second Y-direction scanned copy 204 pairs of raised items 304 has multiple, and in the present embodiment, scan mode is first coarse scan, rear accurate scan.Although the present embodiment only illustrates the scan pattern of accurate scan after first coarse scan, as long as same object can be reached for the scan mode of other modes also belong to protection scope of the present invention.First coarse scan, the step of rear accurate scan is specially:
S301: the second Y-direction scanned copy slowly scans described raised item with larger or less rotation stepping angle;
S302: an OCT tomoscan picture group of raised item described in described OCT imaging system acquires;
S303: the width figure that in a described OCT tomoscan picture group, overall signal is the strongest found out by computing machine, determines that described second Y-direction scanned copy roughly scans center position Y21;
S304: described second Y-direction scanned copy coordinates the first Y-direction scanned copy to described raised item fine scanning with the described center position Y21 that roughly scans;
S305: the 2nd OCT tomoscan picture group of raised item described in described OCT imaging system acquires;
S306: the sequence number of the width figure that overall signal is the strongest in described 2nd OCT tomoscan picture group found out by computing machine, determines the accurate scan center Y22 of the second Y-direction scanned copy.
Particularly, be equivalent to allow the rotating mechanism of the second Y-direction scanned copy 204 coordinate the rotating mechanism of the first Y-direction scanned copy 202, carry out two-dimensional scan.So-called two-dimensional scan herein, namely allows the second Y-direction scanned copy 204 centered by rotation center Y20, and with a less or larger angle of rotation for rotating stepping angle, slowly scans raised item 304.When the second Y-direction scanned copy 204 often rotates a stepping angle, the first Y-direction scanned copy 202 centered by rotation center Y10, and rotates a cycle with certain corner amplitude.Now OCT imaging system 100 gathers an OCT tomoscan picture group of raised item 304, computing machine finds out the strongest that width figure of overall signal from an OCT tomoscan picture group, thus determines that the second Y-direction scanned copy 204 roughly scans center position Y21.OCT imaging system 100 gathers the 2nd OCT tomoscan picture group of raised item 304 again, and the strongest that width figure of overall signal is found out from the 2nd OCT tomoscan picture group, second Y-direction scanned copy 204 is now to raised item 304 accurate scan, determine its accurate scan center Y22. now, second Y-direction scanned copy 204 physical scan area center line overlaps with the primary optical axis of light path, and its debugging calibration operation is complete.
After the second Y-direction scanned copy 204 rotates one-period, the rotating mechanism being equivalent to the first Y-direction scanned copy 202 and the second Y-direction scanned copy 204 has carried out scanning simultaneously.
S203: described first Y-direction scanned copy scans described raised item with preliminary sweep center of rotation Y10, determine its accurate scan center Y11, and with described accurate scan center Y11 scanning rotation, the physical scan area center line of described first Y-direction scanned copy is overlapped with the primary optical axis of light path.
Particularly, after the second Y-direction scanned copy 204 determines its accurate scan center Y22, keep motionless.Putting before this, determining the first Y-direction scanned copy 202 accurate scan center Y11.Be specially: the first Y-direction scanned copy 202 pairs raised item 304 scans, OCT imaging system 100 gathers the 2nd OCT faulted scanning pattern of raised item 304; The accurate scan center Y11 of the corresponding described first Y-direction scanned copy of secondary series pixel L0 ' (not shown) at one article of seamed edge line place of the 2nd OCT faulted scanning pattern protrusions described in computer-made decision article; Accurate scan center Y11 is set to the center of rotation parameter of the first Y-direction scanned copy by computing machine, first Y-direction scanned copy rotates with the rotation center scanning after calibration, and the physical scan area center line of described first Y-direction scanned copy is overlapped with the primary optical axis of light path.Therefore the calibration of method with X-direction scanned copy 201 of the accurate scan center Y11 needed for the first Y-direction scanned copy 202 is confirmed.
To in step S303 and S306, in one OCT tomoscan picture group or the 2nd OCT tomoscan picture group, the defining method of the width figure that overall signal is the strongest is: when primary optical axis is incident, light beam is returned through the surface reflection of raised item 304, and seamed edge line 3041 be raised item 304 by inboard that, nearest from debugging cylinder lens 303.Be arranged on the existence of the small through hole 3021 due to pressure mirror circle 302 of debugging cylinder 301 bottom inside, when the turned position of the second Y-direction scanned copy 204 is the closer to required accurate scan center Y22, after the first Y-direction scanned copy 202 scans one-period, the overall signal of the OCT imaging of the raised item 304 that OCT imaging system 100 collects is stronger.The turned position of the second Y-direction scanned copy 204 more depart from accurate scan center Y22 far away time, the small through hole of pressure mirror circle 302 is more because blocking light, and makes integral image signal more weak.
embodiment 3: the calibration of debugging cartridge 300 pairs of Y-direction scan components, now Y-direction scan components is only containing the first Y-direction scanned copy 202 or the second Y-direction scanned copy 204.In this case, identical with to the calibration steps of X-direction scanned copy to the calibration of Y-direction scanned copy, be not repeated at this.
See Fig. 5, the present invention also disclosed a kind of debugging cartridge 300, comprises, debugging cylinder 301.The cylindrical shape that debugging cylinder 301 is closed in one end.The inside bottom of debugging cylinder 301 is provided with raised item 304, and a seamed edge line 3041 of raised item protrudes to the inside, and the object done like this is conducive to OCT imaging system can collect that width figure that in the tomoscan picture group of raised item 304, overall signal is the strongest.In addition, raised item 304 meets system beam coherence distance, to meet OCT imaging requirements just to the distance of probe light path system 200.
The madial wall of debugging cylinder 301 is then disposed with debugging cylinder lens 303 and pressure mirror circle 302.Pressure mirror circle 302 is arranged on the outside of debugging cylinder lens 303, is provided with the through hole 3021 passed through for light path in the middle part of pressure mirror circle 302.The position of through hole 3021 just and the position consistency of the convergent point of scanning light beam center line, to meet OCT imaging demand.As previously described, utilize debugging cartridge 300, can, easily to X-direction scanned copy 201, first Y-direction scanned copy 202 and the second Y-direction scanned copy 204 realization calibration of scanister, their scanning area center line be consistent with system light path primary optical axis L2.
Certainly, when outer probe light path system 200 changes, debugging cartridge 300 can change, but constant for the calibrating principle of X, Y-direction scanister scanning center. particularly, it is exactly remove debugging cylinder lens 303 and pressure mirror circle 302 that debugging cylinder 300 structure specifically changes, and only retains debugging cylinder 301 and raised item 304, but now, also demand fulfillment raised item meets system beam coherence distance just to the distance of described probe light path system, and other structure does not do any change.Eliminate debugging cylinder lens 303 and pressure mirror circle 302, debugging cartridge 300 equally can to the scanister calibration of probe light path system 200.
With reference to figure 4, the present invention also disclosed a kind of system of debugging scanister, comprises, the debugging cartridge 300 set gradually according to light path, probe light path system 200 and OCT imaging system 100.By using on this system by debugging cartridge 300, the function scanister of probe light path system 200 being realized to calibration can be realized.The scanister of probe light path system 200 described herein, comprises aforesaid X-direction scanned copy 201, first Y-direction scanned copy 202 and the second Y-direction scanned copy 204.
Beneficial effect of the present invention: the raised item of X-direction scanned copy scanning debugging cartridge, the OCT faulted scanning pattern of OCT imaging system acquires raised item section, find out the center position X1 needed for X-direction scanned copy now, X-direction scanned copy scans with center X1, thus the physical scan area center line of X-direction scanned copy overlaps with the primary optical axis of light path, reach the object that the rotation center of X-direction scanned copy is calibrated;
Y-direction scanister comprises the first Y-direction scanned copy and the second Y-direction scanned copy, second Y-direction scanned copy coordinates the first Y-direction scanned copy, first to raised item coarse scanning then accurate scan, calibrate the rotation center position Y22 of the second Y-direction scanned copy, then the second Y-direction scanned copy goes to rotation center position, the first Y-direction scanned copy is allowed to scan raised item again, identical with X-direction determination rotation center location method, determine the accurate scan center Y11 of the first Y-direction scanned copy, treat second, after the rotation center of one Y-direction scanned copy is all calibrated, the physical scan area center line of Y-direction overlaps with the primary optical axis L2 of system light path, reach the object that the rotation center of Y-direction scan components is calibrated.
In present patent application file, the accurate scan center Y11 of the accurate scan center Y22 of described second Y-direction scanned copy, the roughly scanning center position Y21 of the second Y-direction scanned copy, the first Y-direction scanned copy is identical with the defining method of the center position X1 of described X-direction scanned copy.Although different with numerical value concrete in the computing formula in the center position X1 of X-direction scanned copy, its Computing Principle is identical, do not state tired at this.
Therefore, utilize the debugging X-direction scanned copy of cartridge to scanister and/or the adjustment of Y-direction scan components, following effect can being realized: 1, without the need to taking shell apart, just can realize the calibration to them, thus make debugging efforts simple, quick; 2, debug process is simple, even if the personnel not possessing professional knowledge utilize the method and equipment debugging scanister, also can debug out satisfied result.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.
Claims (14)
1. debug the method for cartridge calibration scan device, it is characterized in that, comprise and the X-direction scanned copy of described scanister is calibrated and/or calibrated Y-direction scan components;
Described calibration X-direction scanned copy comprises:
Raised item in described X-direction scanned copy scanning debugging cartridge, one OCT faulted scanning pattern of raised item described in OCT imaging system acquires, the center position X1 of the described X-direction scanned copy that the first row pixel L0 at one article of seamed edge line place of raised item described in an OCT faulted scanning pattern is corresponding described in computer-made decision;
The center position X1 of described X-direction scanned copy is set to its center of rotation parameter by computing machine; Described X-direction scanned copy rotates with described center position X1 scanning, and its physical scan area center line is overlapped with the primary optical axis of light path;
Described to the calibration of Y-direction scan components, comprising:
Define described Y-direction scan components and comprise the first Y-direction scanned copy and/or the second Y-direction scanned copy;
If described Y-direction scan components comprises the first Y-direction scanned copy and the second Y-direction scanned copy, then:
Described second Y-direction scanned copy scans described raised item, determines its accurate scan center Y22, and the physical scan area center line of described second Y-direction scanned copy is overlapped with the primary optical axis of light path;
Described first Y-direction scanned copy scans described raised item with preliminary sweep center of rotation Y10, determine its accurate scan center Y11, and scan rotation with described accurate scan center Y11, the physical scan area center line of described first Y-direction scanned copy is overlapped with the primary optical axis of light path;
If described Y-direction scan components only includes the first Y-direction scanned copy or only includes the second Y-direction scanned copy, then:
Described to the first Y-direction scanned copy or the second Y-direction scanned copy calibration steps identical with to described X-direction scanned copy calibration steps.
2. the method for debugging cartridge calibration scan device as claimed in claim 1, is characterized in that: the defining method of the center position X1 of described X-direction scanned copy is: according to formula
Wherein, N is an OCT faulted scanning pattern Width pixel count, N1 is the pixel count between the first row pixel L0 at the centre line L 1 of an OCT faulted scanning pattern and one article of seamed edge line place of raised item, X0 is the initial rotation center of X-direction scanned copy, Xmax is the X-direction scanister scanning total angle of rotation, and X1 is the center position after the calibration of X-direction scanned copy; N, X0, Xmax are systemic presupposition data, and N1 is drawn by computer calculate, just can obtain X1 by above formula.
3. the method for debugging cartridge calibration scan device as claimed in claim 1, it is characterized in that: scan the raised item in described debugging cartridge at described X-direction scanned copy, the OCT faulted scanning pattern of raised item described in OCT imaging system acquires, before the center position X1 step of the described X-direction scanned copy that the first row pixel L0 at a seamed edge line place of OCT faulted scanning pattern protrusions bar is corresponding described in computer-made decision, also comprise:
Debugging cartridge, probe light path system and OCT imaging system is set gradually according to light path; Described probe light path system comprises described X-direction scanned copy and described Y-direction scan components.
4. the method for debugging cartridge calibration scan device as claimed in claim 3, is characterized in that: describedly set gradually debugging cartridge according to light path, specifically comprises:
Described raised item be placed on debugging cylinder bottom inside and a wherein seamed edge line of described raised item is given prominence to towards described debugging cylinder bottom inside, making described raised item just meet system beam coherence distance to the distance of described probe light path system simultaneously;
When to described X-direction scanned copy calibration debugging, described seamed edge line all keeps vertical with the rotation axis of described X-direction scanned copy and the rotation axis of described first Y-direction scanned copy; When to described Y-direction scan components calibration debugging, the rotation axis of described seamed edge line and described first Y-direction scanned copy and/or the equal keeping parallelism of turning axle of the second Y-direction scanned copy;
Debugging cylinder lens, pressure Jing Quan are successively set in debugging cylinder inside circumference, and the position making the through hole on described pressure Jing Quan just and the position consistency of the convergent point of scanning light beam center line.
5. the method for debugging cartridge calibration scan device as claimed in claim 1, is characterized in that: described to X-direction scanned copy calibration steps before, also comprise:
Described first Y-direction scanned copy is gone to its rotation center position Y10 and/or the rotating mechanism of described second Y-direction scanned copy is gone to its rotation center Y20.
6. debug the method for cartridge calibration scan device as described in claim 2, it is characterized in that: described second Y-direction scanned copy scans described raised item, determine that in the Y22 of its accurate scan center, described scanning is accurate scan after first coarse scan, comprising:
Second Y-direction scanned copy slowly scans described raised item with larger or less rotation stepping angle;
One OCT tomoscan picture group of raised item described in described OCT imaging system acquires;
The width figure that in a described OCT tomoscan picture group, overall signal is the strongest found out by computing machine, determines that described second Y-direction scanned copy roughly scans center position Y21;
Described second Y-direction scanned copy coordinates the first Y-direction scanned copy to described raised item fine scanning with the described center position Y21 that roughly scans;
Described OCT imaging system gathers the 2nd OCT tomoscan picture group of described raised item again;
The sequence number of the width figure that overall signal is the strongest in described 2nd OCT tomoscan picture group found out by computing machine, determines the accurate scan center Y22 of the second Y-direction scanned copy.
7. the method for debugging cartridge calibration scan device as claimed in claim 6, it is characterized in that: described first Y-direction scanned copy scans described raised item with preliminary sweep center of rotation Y10, determine its accurate scan center Y11, the step that the physical scan area center line of described first Y-direction scanned copy is overlapped with the primary optical axis of light path is:
Described first Y-direction scanned copy scans described raised item with preliminary sweep center of rotation Y10;
2nd OCT faulted scanning pattern of raised item described in OCT imaging system acquires;
The accurate scan center Y11 of the corresponding described first Y-direction scanned copy of secondary series pixel L0 ' at one article of seamed edge line place of the 2nd OCT faulted scanning pattern protrusions described in computer-made decision article;
The accurate scan center Y11 of the first Y-direction scanned copy is set to the center of rotation parameter of the first Y-direction scanned copy by computing machine, described first Y-direction scanned copy scans with described accurate scan center Y11 and rotates, and the physical scan area center line of described first Y-direction scanned copy is overlapped with the primary optical axis of light path.
8. the method for the debugging cartridge calibration scan device according to any one of claim 6-7, is characterized in that: the method that the width figure that overall signal is the strongest in a described OCT tomoscan picture group or the 2nd OCT tomoscan picture group found out by computing machine is:
When light beam is incident along primary optical axis, through described raised item surface reflection and the turned position of the second Y-direction scanned copy the closer to its accurate scan center Y22 time, the image of OCT imaging system acquires is a width figure the strongest in a described OCT tomoscan picture group or the 2nd OCT tomoscan picture group.
9. the method for the debugging cartridge calibration scan device according to any one of claim 6-7, is characterized in that: the accurate scan center Y22 of described second Y-direction scanned copy, the roughly scanning center position Y21 of the second Y-direction scanned copy are identical with the defining method of the accurate scan center Y11 of the first Y-direction scanned copy defining method that is equal and the described center position X1 to X-direction scanned copy.
10. debug a cartridge, it is characterized in that, comprising: the debugging cylinder of hollow and be arranged on the raised item of its bottom inside, along a crest line of described raised item to projecting inward; Described raised item meets system beam coherence distance just to the distance of probe light path system.
11. debug cartridge as claimed in claim 10, it is characterized in that: also comprise and be arranged on debugging cylinder lens on inside described debugging cylinder and pressure Jing Quan from inside to outside; The through hole passed through for light source is offered in the middle of described pressure mirror circle; The position of described through hole just and the position consistency of the convergent point of scanning light beam center line.
12. debugging cartridges according to any one of claim 10-11, is characterized in that: the section perpendicular to a crest line of described raised item is at least the one of V-arrangement, triangle or arch.
13. 1 kinds of systems of debugging scanister, is characterized in that, comprising: the debugging cartridge set gradually according to light path, probe light path system and OCT imaging system, and described probe light path system comprises: X-direction scanned copy and/or Y-direction scan components; Described debugging cartridge comprises: the debugging cylinder of hollow and be arranged on the raised item of its bottom inside, along a crest line of described raised item to projecting inward; Described raised item meets system beam coherence distance just to the distance of described probe light path system.
The system of 14. debugging scanister as claimed in claim 13, is characterized in that: described Y-direction scan components comprises the first Y-direction scanned copy and/or the second Y-direction scanned copy.
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| JP5079755B2 (en) * | 2009-08-06 | 2012-11-21 | 国立大学法人 筑波大学 | Calibration method for components of optical coherence tomography |
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Address after: 518000 803, block B, Jingang center, Jingang building, houye community, Xixiang street, Bao'an District, Shenzhen, Guangdong Patentee after: Shenzhen moting Medical Technology Co.,Ltd. Address before: 518112 Room 601, No. 3, Juyin technology industrial plant, No. 1, Ganli Road, gankeng community, Buji street, Longgang District, Shenzhen, Guangdong Patentee before: SHENZHEN CERTAINN TECHNOLOGY Co.,Ltd. |
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