CN102817818A - Electrolysis micropump for double-fluid synchronous transmission - Google Patents
Electrolysis micropump for double-fluid synchronous transmission Download PDFInfo
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- CN102817818A CN102817818A CN2012103167021A CN201210316702A CN102817818A CN 102817818 A CN102817818 A CN 102817818A CN 2012103167021 A CN2012103167021 A CN 2012103167021A CN 201210316702 A CN201210316702 A CN 201210316702A CN 102817818 A CN102817818 A CN 102817818A
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Abstract
An electrolysis micropump for double-fluid synchronous transmission comprises a pump body, electrodes, a metal tube and a one-way valve. The pump body comprises a pump body upper piece, a pump body middle piece and a pump body lower piece. The pump body upper piece is provided with a first pumping chamber. The pump body middle piece is provided with an electrolysis chamber. The pump body lower piece is provided with a second pumping chamber. A first pump membrane is disposed between the first pumping chamber and the electrolysis chamber. A second pump membrane is disposed between the second pumping chamber and the electrolysis chamber. The pump body upper piece, the first pump membrane, the pump body middle piece, the second pump membrane and the pump body lower piece are fixed to form a 'sandwich' structure. The electrolysis micropump is capable of transmitting two fluids synchronously. Compared with a single-passage micropump, double-fluid synchronous transmission is achieved, output flow is continuous and adjustable, complete self-priming is achieved, and circulating operation is achieved. In addition, the electrolysis micropump can be made by micro-machining and micromachining technology compatible materials and process, and the electrolysis micropump is small, light, low in power consumption, easy for integration and the like.
Description
Technical field
The invention belongs to the microelectromechanical systems field, particularly microfluid transmission and control technique relate in particular to a kind of new micro pump structure design.
Background technique
Microfluid system has become popular research field in recent years.Micropump is the important symbol of its development level as the performer of an important micro-flow system.Micropump has or not movable valve block to be divided into according to it has valve type Micropump and valveless type Micropump.Valve type Micropump is arranged often based on Mechanical Driven, principle is simple, and manufacturing process is ripe, is easy to control, is the main flow of using at present; The valveless type Micropump then usually utilizes the new features of fluid under minute yardstick, and principle is relatively more novel, is more suitable for microminiaturization, has bigger development prospect.
Micropump also has significant utilization in medical treatment; For example in doing the process of some operation; Operating time is long, scope is big, retardance is regulated and control and the flesh pine requires high; At this moment just can level of anesthesia and effect accurately be controlled with Micropump infusion anesthetic lentamente, thus satisfy operation technique needs, reduce that the patient is uncomfortable, the generation that prevents bad reaction, alleviate the patient suffering.Micropump can also be used as doser, and for example, available Micropump is carried panting property of magnesium sulfate treatment children PUD D, and with the patient of Micropump drug treatment DVT, extensive use is to be used for carrying insulin for treating diabetes.
At present, the conventional method of oncotherapy has operation, radiotherapy, chemotherapy, ablation and molecular biological complementary therapy.There is narrow limitation in operative treatment.Radiation and chemotherapy also can damage normal tissues in the treatment tumour.Biotherapy is little to the human body wound, but still is in the stage of supplemental treatment or clinical trial, does not become the treatment means of main flow as yet.What research was maximum at present is ablation, and the diversity that melts principle causes equipment to vary.Generally can the ablation method roughly be divided into heating ablation method and chemical ablation method clinically.
Implementing of having in the method for treatment tumour is very complicated, and equipment requirements is also very high, and the volume of relevant device is also just bigger.Realize and the combining of Micropump that then require the volume of therapeutic equipment very little, control apparatus also must be very little.From this consideration, realize and the combining of Micropump that a kind of suitable ablation method is suggested, it is exactly that thermochemistry melts method.Thermochemistry melts method through injecting one or more chemical ablation things to human body, and utilizes between the chemical ablation thing or heat production that itself and substance in vivo react destroys tumor tissues.This method had both kept the protein coagulation effect of chemical ablation agent to tumour, had reached the effect of thermotherapy again, and both combinations can realize higher-quality ablation effect, thereby solved the problem of chemical ablation high relapse rate.The more important thing is that the chemical reaction product that is utilized often toxicity is less, can eliminate or reduce the residual toxicity that melts reagent to health like this, realize the theory of " green remedy ".
The acid-base neutralization reaction just belongs to a kind of of thermal chemical reaction ablation method, is example with NaOH and HCl reaction, chemical reaction NaOH+HCl=NaCl+H
2Two characteristics are arranged in the O process: 1. the heat of neutralization reaction release is △ H=57.32kJ/mol, and a spot of reactant can bring significant heat release; 2. after the acid-base solution that proportioning is suitable was accomplished reaction, its residue was NaCl and water, is physiological saline common in the human body, and reaction residue is to the influence of human body less (whether intermediate product has toxicity needs further assessment).Therefore, based on the neutralization reaction of local injection acid-base solution, can implement precision destruction to tumour.Compare with traditional thermotherapy measure, this is a kind of heating ablation method of height localization.Because the solution injected is in normal temperature, and release heat just behind the target approach position only, thereby can not cause fire damage to health tissues on the way; Simultaneously, if the pin diameter of the implantable injection that is used as less (< l mm) can effectively be avoided the mechanical trauma that tissue is caused because of puncture.From then on meaning is said, this is a kind of knub thermotherapy of real Wicresoft.And when practice; Just can be earlier by the size and the position of definite tumours such as image documentation equipment such as B ultrasonic, CT, nuclear magnetic resonance; According to the suitable therapeutic scheme of laboratory data design; As confirming chemical reactant, using dosage, injection areas etc., intubate is received through operation carried out injection for curing in the tumor tissues then.Can find out that from this this method need not to increase the additional expensive equipment, thereby operation cost and medical expense is lower.
Usually adopt two kinds of fluids of two single fluid Micropump transmission at present in the existing technology, so not only cause the cost of system to increase, the more important thing is the synchronous transfer that is difficult for guaranteeing two kinds of solution.
Summary of the invention
The objective of the invention is to propose a kind of electrolysis Micropump that is used for the two-fluid synchronous transfer, to solve the problem that single fluid transmission Micropump of the prior art can not guarantee two kinds of fluid synchronous transfer.
For realizing above-mentioned purpose, technological scheme of the present invention is following: a kind of electrolysis Micropump that is used for the two-fluid synchronous transfer is characterized in that: this electrolysis Micropump contains the pump housing, electrode, metal tube and one-way valve; The said pump housing is made up of sheet under the sheet and the pump housing in the pump housing last slice, the pump housing, is provided with the first pumping chamber in the pump housing last slice, is provided with the electrolysis chamber in the pump housing in the sheet, is provided with the second pumping chamber under the pump housing in the sheet; Between the first pumping chamber and electrolysis chamber, be provided with first pumping diaphragm, between the second pumping chamber and electrolysis chamber, be provided with second pumping diaphragm; In the said pump housing last slice, first pumping diaphragm, the pump housing under sheet, second pumping diaphragm and the pump housing sheet be fixed together, form " sandwich " formula structure; Be placed with catalyzer in the electrolysis chamber, two electrodes are placed in the electrolysis chamber; Said metal tube adopts four at least, is separately positioned on the first pumping chamber and the second pumping chamber import and export, and every metal tube all is connected with an one-way valve through flexible pipe.
The sectional shape of the first pumping chamber according to the invention, the second pumping chamber and electrolysis chamber is square or circle.
Sheet is incorporated into one in the said electrode and the pump housing; The metal tube and the pump housing last slice that are arranged on the first pumping chamber import and export are combined as a whole; Be arranged on that sheet is combined as a whole under metal tube and the pump housing of the second pumping chamber import and export.
In the said pump housing last slice, first pumping diaphragm, the pump housing under sheet, second pumping diaphragm and the pump housing sheet be fixed together through screw bolt and nut; In the pump housing, be provided with round boss around the tapped hole of the upper and lower surfaces of sheet.
The present invention has the following advantages and the high-lighting effect:
One), the present invention can transmit two kinds of fluids simultaneously, with respect to the single channel Micropump, can effectively solve the problem of two-fluid synchronous transfer, makes adjustable continuously, the complete self-priming of output flow.Has synchronism preferably, the work that can move in circles.
Two), the present invention can adopt micro machining, micro mechanical technology compatible mutually material and technology manufacturing, has characteristics such as little, in light weight, low in energy consumption and easy of integrationization of volume.
Three), the thermochemistry therapy of the present invention and tumour combines, and the advantage of the following aspects is arranged:
1. guaranteed the synchronous transfer of bronsted lowry acids and bases bronsted lowry solution: select the acid-base solution of suitable concn, just can guarantee that acid-base solution all reacts completely, do not have residue, health tissues is damaged.
2. control is simple: chemical reactant, using dosage, implantation zone etc. all are to confirm in advance well, only need to control through the control electric current flow of acid-base solution in treating, and the succinct then reaction liberated heat of controlling just can be controlled therapeutic process.
Description of drawings
Fig. 1 is a two-fluid Micropump embodiment's provided by the invention structural principle schematic representation (front section view).
Fig. 2 is a flexible pipe and the schematic representation that is connected of metal tube and one-way valve.
Fig. 3 is the stereogram of sheet in the pump housing.
Fig. 4 is the stereogram of sheet under the pump housing last slice and the pump housing.
Among the figure: the 1-pump housing last slice; Sheet in the 2-pump housing; Sheet under the 3-pump housing; The 4-first pumping chamber; 5-electrolysis chamber; The 6-second pumping chamber; 7-first pumping diaphragm; 8-second pumping diaphragm; The 9-electrode; The 10-catalyzer; The 11-metal tube; The 12-flexible pipe; The 13-one-way valve; The 14-boss.
Embodiment
To combine accompanying drawing that principle of the present invention, structure and practical implementation are specified below.
As shown in Figure 1, two-fluid electrolysis Micropump provided by the invention contains the pump housing 1, electrode 9, metal tube 11 and one-way valve 13; The said pump housing is made up of sheet 3 under the sheet 2 and the pump housing in the pump housing last slice 1, the pump housing; Be provided with the first pumping chamber 4 in the pump housing last slice, be provided with electrolysis chamber 5 in the pump housing in the sheet, be provided with the second pumping chamber under the pump housing in the sheet; Pump housing material can be selected the material of antiacid caustic corrosion for use, like organic glass etc.; Between the first pumping chamber and electrolysis chamber, be provided with first pumping diaphragm 7, between the second pumping chamber and electrolysis chamber, be provided with second pumping diaphragm 8; In the said pump housing last slice 1, first pumping diaphragm 7, the pump housing under sheet 2, second pumping diaphragm 8 and the pump housing sheet 3 be fixed together, form " sandwich " formula structure; Being placed with 10, two electrodes of catalyzer in the electrolysis chamber 5 is placed in the electrolysis chamber; Metal tube adopts four, is separately positioned on the first pumping chamber and the second pumping chamber import and export, and every metal tube all is connected with an one-way valve through flexible pipe 12.
Fig. 2 is a flexible pipe and the schematic representation that is connected of metal tube and one-way valve, utilizes the stretchability of flexible pipe to realize the sealing of runner, and every metal tube all is connected with an one-way valve through flexible pipe 12.
Fig. 3 is the stereogram of sheet in the pump housing, and the centre is the square through hole of band fillet, and both sides have a minimum passage to be used to place electrode respectively; There are some through holes to be used to place screw around the pump housing.There is a round boss upper and lower surfaces of sheet in the pump housing around tapped hole; Boss is to the extruding great efforts of other pump housings parts of the extrusion ratio of pumping diaphragm to pumping diaphragm; So both can fix pumping diaphragm; Yet can not spend big to the extruding force of pumping diaphragm and make the pumping diaphragm distortion, can also prevent that fluid flows out in tapped hole because of the pump housing.
Fig. 4 is the stereogram of sheet under the pump housing last slice and the pump housing, and the centre is the square through hole groove with band fillet of certain depth, and both sides are the import and export of pumping chamber, are used to place metal tube, through Bond the metal tube and upper and lower of the pump housing are combined as a whole; There are some through holes to be used to place screw around the pump housing.
During concrete the assembling, use sealer that sheet in the pump housing 2 and two electrodes 9 are bonded together earlier, the pump housing last slice 1 is bonded together with metal tube 11, and sheet 3 is bonded together with metal tube under the pump housing, and the opening end at metal tube overlaps top hose 12 and one-way valve 13 again; Through screw sheet 3 under sheet in the pump housing 2, second pumping diaphragm 8, the pump housing is fixed together, the solution for preparing is injected electrolysis chamber 5, guarantee not exist leakage; Add the screw and nut of screwing simultaneously with first pumping diaphragm 7 with the pump housing last slice 1 this moment again; Use sealer to seal whole Micropump at last.When this electrolysis Micropump was loaded voltage rating, present embodiment can work as the micropump use, can self-priming; When to this device loads VDC, can work as two miniature valves uses.
During concrete the use, the flexible pipe of ingress is inserted respectively in two kinds of fluids, appointed part is placed in the outlet of the flexible pipe in outlet port respectively, can add that also syringe needle inserts in the tissue.Two electrodes with Micropump are linked in the circuit of being made up of power supply, adjustable resistance, switch again, can use the electrolysis Micropump.
Embodiment:
The Manufacturing material of the two-fluid Micropump in this instance and component all have antiacid caustic corrosion characteristic; What wherein the Manufacturing material of the Micropump pump housing was selected for use is the thick poly (methyl methacrylate) plate of 2mm (PMMA); The Manufacturing material of pumping diaphragm is the thick silica gel thin film of 0.2mm; Catalyzer 10 usefulness be platinum black, electrode 9 is platinum electrode silks of 0.5mm diameter, one-way valve 13 be the F2804-40 one-way valve produced of thunder fluid Control Engineering Co., Ltd.In addition, metal tube is that external diameter is the Stainless Steel Tube of 1mm, and flexible pipe 12 uses the silica gel hose of external diameter 3mm, is used for connecting Micropump and one-way valve.The encapsulation usefulness of the whole pump housing be the screw of M1.4 * 8mm and the nut of M1.4.
The technical parameter of the embodiment of the invention: boundary dimension is 14mmX11mmX6mm (the wide X of long X is high), and the electrolyte chamber chamber size is 8mmX3.8mmX2mm (the wide X of long X is high), and the pumping chamber size is 8mmX3.8mmX1.5mm (the wide X of long X is high).Na with 5%
2SO
4Solution is as electrolytic solution, and two kinds of fluids are selected 37.5%HCl solution and 40%NaOH solution respectively for use.
The cell reaction of this instance will produce hydrogen and oxygen, and the while is in the catalysis generation redox reaction of platinum.Under 3V voltage, test to such an extent that Peak Flow Rate reaches 28 μ Lmin
-1Heat through adopting the acid-base neutralization reaction to emit is carried out the thermochemistry ablation therapy to tumour, has good application prospect.
Claims (5)
1. electrolysis Micropump that is used for the two-fluid synchronous transfer, it is characterized in that: this electrolysis Micropump contains the pump housing, electrode (9), metal tube (11) and one-way valve (13); The said pump housing is made up of sheet (3) under the sheet (2) and the pump housing in the pump housing last slice (1), the pump housing; Be provided with the first pumping chamber (4) in the pump housing last slice (1); Be provided with electrolysis chamber (5) in the sheet in the pump housing (2), be provided with the second pumping chamber (6) in the sheet under the pump housing (3); Between the first pumping chamber (4) and electrolysis chamber (5), be provided with first pumping diaphragm (7), between the second pumping chamber (6) and electrolysis chamber (5), be provided with second pumping diaphragm (8); In the said pump housing last slice, first pumping diaphragm, the pump housing under sheet, second pumping diaphragm and the pump housing sheet be fixed together, form " sandwich " formula structure; Be placed with catalyzer (10) in the electrolysis chamber, two electrodes are placed in the electrolysis chamber (5); Said metal tube adopts four at least, is separately positioned on the import and export of the first pumping chamber (4) and the second pumping chamber (6), and every metal tube (11) all is connected with an one-way valve (13) through flexible pipe (12).
2. a kind of electrolysis Micropump that is used for the two-fluid synchronous transfer as claimed in claim 1 is characterized in that: the sectional shape of the said first pumping chamber, the second pumping chamber and electrolysis chamber is square or circle.
3. a kind of electrolysis Micropump that is used for the two-fluid synchronous transfer as claimed in claim 1 is characterized in that: sheet (2) is incorporated into one in the said electrode (9) and the pump housing; The metal tube and the pump housing last slice that are arranged on first pumping chamber (4) import and export are combined as a whole; Be arranged on that sheet is combined as a whole under metal tube and the pump housing of second pumping chamber (6) import and export.
4. a kind of electrolysis Micropump that is used for the two-fluid synchronous transfer as claimed in claim 1 is characterized in that: in the said pump housing last slice (1), first pumping diaphragm (7), the pump housing under sheet (2), second pumping diaphragm (8) and the pump housing sheet (3) be fixed together through screw bolt and nut.
5. a kind of electrolysis Micropump that is used for the two-fluid synchronous transfer as claimed in claim 5 is characterized in that: be provided with round boss (14) around the tapped hole of the upper and lower surfaces of sheet in the pump housing (2).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012103167021A CN102817818A (en) | 2012-08-30 | 2012-08-30 | Electrolysis micropump for double-fluid synchronous transmission |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012103167021A CN102817818A (en) | 2012-08-30 | 2012-08-30 | Electrolysis micropump for double-fluid synchronous transmission |
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| CN102817818A true CN102817818A (en) | 2012-12-12 |
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| CN2012103167021A Pending CN102817818A (en) | 2012-08-30 | 2012-08-30 | Electrolysis micropump for double-fluid synchronous transmission |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103511230A (en) * | 2013-10-08 | 2014-01-15 | 新疆大学 | Double-cavity type electric actuator valveless micropump |
| CN107569764A (en) * | 2017-08-24 | 2018-01-12 | 任鹏涛 | One kind is based on the micro- electromagnetism anal intestine postoperative administration devices of PDMS |
| CN112664675A (en) * | 2020-12-04 | 2021-04-16 | 浙江大学 | Electric conjugate liquid driven flow control low noise soft valve |
| CN113855212A (en) * | 2021-10-28 | 2021-12-31 | 海杰亚（北京）医疗器械有限公司 | Cold and hot ablation apparatus, cold and hot ablation system and control method thereof |
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| CN101526078A (en) * | 2009-04-02 | 2009-09-09 | 上海交通大学 | Precision liquid-gas transmission and matching machine based on piezoelectric material |
| CN101960144A (en) * | 2008-07-08 | 2011-01-26 | 松下电器产业株式会社 | Fluid conveying device using electrically conductive polymer |
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| CN2715765Y (en) * | 2002-12-30 | 2005-08-10 | 中国科学院理化技术研究所 | Thermotherapy device for extracorporeal circulation |
| JP4320721B2 (en) * | 2003-10-02 | 2009-08-26 | 株式会社ニッキ | Pulsating diaphragm fuel pump |
| JP2005207406A (en) * | 2003-10-30 | 2005-08-04 | Eamex Co | Pump containing conductive high polymer and method of driving the pump |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103511230A (en) * | 2013-10-08 | 2014-01-15 | 新疆大学 | Double-cavity type electric actuator valveless micropump |
| CN103511230B (en) * | 2013-10-08 | 2016-01-20 | 新疆大学 | A kind of bicavate electric actuation valve free pump |
| CN107569764A (en) * | 2017-08-24 | 2018-01-12 | 任鹏涛 | One kind is based on the micro- electromagnetism anal intestine postoperative administration devices of PDMS |
| CN107569764B (en) * | 2017-08-24 | 2020-04-21 | 任鹏涛 | Based on little electromagnetism anus intestines postoperative device of dosing of PDMS |
| CN112664675A (en) * | 2020-12-04 | 2021-04-16 | 浙江大学 | Electric conjugate liquid driven flow control low noise soft valve |
| CN112664675B (en) * | 2020-12-04 | 2022-05-31 | 浙江大学 | Electric conjugate liquid driven flow control low noise soft valve |
| CN113855212A (en) * | 2021-10-28 | 2021-12-31 | 海杰亚（北京）医疗器械有限公司 | Cold and hot ablation apparatus, cold and hot ablation system and control method thereof |
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Application publication date: 20121212 |