CN102793979B - Proton or heavy ion beam cancer treatment device - Google Patents

Abstract

The invention relates to a proton or heavy ion beam cancer treatment device. A proton or heavy ion beam cancer treatment device, including a synchrotron, its main feature is that an ion source is provided at the front end of the synchrotron, the ion source is an electron cyclotron resonance ion source, and the electron cyclotron resonance ion source passes through the source beam The 0Q01 glasser quadrupole lens and the 0Q02 glasser lens on the line, the 1st dipole iron-connected RF quadrupole field linear accelerator, the 1st quadrupole magnet, the 2nd quadrupole magnet, and the 3rd quadrupole on the medium energy beamline The magnet and the fourth quadrupole magnet are provided with a first dipole magnet between the second quadrupole magnet and the third quadrupole magnet, and the fourth quadrupole magnet is connected to the first electrostatic deflection plate of the synchrotron through the first cutting magnet; A high-energy beam is drawn between the 22nd quadrupole magnet and the 31st hexapole magnet of the synchrotron. The invention has the advantages that the linear accelerator can provide higher flow intensity, which is more than 20 times of the current SFC cyclotron flow intensity of the Near Institute of Physics and Technology. The higher the injection flow intensity, the more ions the synchrotron can obtain under the same number of injection cycles. In this way, the transverse aperture of the synchrotron vacuum chamber can be saved, thereby reducing the cost of the synchrotron storage ring.

Description

Proton or heavy ion beam cancer treatment device

technical field

The invention relates to a proton or heavy ion beam cancer treatment device, in particular to a proton cancer treatment device in which a linear accelerator is cascaded with a synchronous storage ring, and is mainly used in the fields of aerospace, biology (medicine) and industry.

Background technique

Because proton and heavy ion beams have the characteristics of inverted depth dose distribution, small side scattering, high relative biological effect and low oxygen increase ratio in the irradiation of organisms, making proton and heavy ion cancer treatment become Today's advanced and effective cancer radiotherapy method in the world; proton and heavy ion beams can simulate the radiation environment in outer space, and are an effective method for aerospace single event effects and instrument radiation resistance detection; the particle radius of heavy ion beams can be selected It is an effective means for the manufacture of nuclear pore membranes.

An accelerator for supplying proton beams and ion beams is the most basic device for performing proton beam and ion beam irradiation. The accelerator provides proton beams and ion beams with different energies according to different experiments and application needs; provides precise ion beam position scanning control according to different shapes of experimental targets; and provides different beam intensities according to effective dose requirements. The synchronous storage ring is the most effective accelerator device to meet such needs. The specific method is: by adjusting the cut-off frequency of the high-frequency accelerating cavity and the corresponding magnetic field strength, it can generate extracted ion beams with different energies; High-frequency scanning can generate uniform ion beam distribution; by controlling the cumulative injection current intensity or controlling the extraction switch, the stored ion beam current intensity can be adjusted to meet the effective dose requirements of the experiment. Therefore, the establishment of proton beam and ion beam acceleration devices with synchrotron as the main body is the basis for carrying out ion irradiation experiments.

Contents of the invention

The object of the present invention is to avoid the deficiency of the prior art and provide a proton or heavy ion beam cancer treatment device. A proton or heavy ion beam cancer treatment device that uses RFQ or RFQ+DTL (Drift Tube Linac) as the synchrotron injector, and multi-circle injection as the injection method of the synchrotron. The invention can irradiate the target with ion beams of different energies and beam current intensities.

In order to achieve the above object, the technical solution adopted by the present invention is: a proton or heavy ion beam cancer treatment device, including a synchrotron, its main feature is that an ion source is provided at the front end of the synchrotron, and the ion source is an electron The cyclotron resonance ion source, the electron cyclotron resonance ion source passes through the 0Q01 glasser quadrupole lens and the 0Q02 glasser lens on the source beamline, the first dipole iron is connected to the radio frequency quadrupole field linear accelerator, and the 14th quadrupole on the medium energy beamline The pole magnet, the second quadrupole magnet, the third quadrupole magnet, and the fourth quadrupole magnet are provided with a first dipole magnet between the second quadrupole magnet and the third quadrupole magnet, and the fourth quadrupole magnet 1. The cutting magnet is connected to the first electrostatic deflection plate of the synchrotron; the high-energy beam is drawn between the 22nd quadrupole magnet and the 31st hexapole magnet of the synchrotron.

The proton or heavy ion beam cancer treatment device also includes a drift tube linear accelerator between the radio frequency quadrupole field linear accelerator and the first quadrupole magnet.

The proton or heavy ion beam cancer treatment device also includes that the high-energy beam line includes a plurality of extraction terminals.

In the proton or heavy ion beam cancer treatment device, the high-energy beamline includes a second cutting magnet connecting the high-energy beamline between the 22nd quadrupole magnet and the 31st hexapole magnet of the synchrotron. 1 quadrupole magnet, the second quadrupole magnet of the high-energy beam line, the first dipole magnet of the high-energy beam line; The line includes the sequential connection of the first quadrupole magnet of the first high-energy beamline, the second quadrupole magnet of the first high-energy beamline, the third quadrupole magnet of the first high-energy beamline, and the fourth quadrupole magnet of the first high-energy beamline; The second high-energy beamline includes the first quadrupole magnet of the second high-energy beamline, the second quadrupole magnet of the second high-energy beamline, the third quadrupole magnet of the second high-energy beamline, and the fourth quadrupole magnet of the second high-energy beamline connected in sequence.

The proton or heavy ion beam cancer treatment device, the synchrotron includes a first electrostatic deflection plate located between the 11th quadrupole magnet and the 62nd quadrupole magnet, and between the 11th quadrupole magnet and the 12th quadrupole magnet The first two-pole magnet of the synchrotron is arranged between the magnets; the twelfth four-pole magnet is connected to the second electrostatic deflection plate, the twenty-first four-pole magnet, and the twenty-second four-pole magnet through the third convex rail magnet, and the twenty-first four-pole magnet The second dipole magnet of the synchrotron is arranged between the 22nd quadrupole magnet; the 22nd quadrupole magnet connects the 31st hexapole magnet and the 31st quadrupole magnet, the 32nd quadrupole magnet, the 41st A quadrupole magnet, the 3rd dipole magnet of the synchrotron is arranged between the 31st quadrupole magnet and the 32nd quadrupole magnet, and the synchrotron high-frequency acceleration chamber is arranged between the 32nd quadrupole magnet and the 41st quadrupole magnet , the 41st quadrupole magnet and the 42nd quadrupole magnet are provided with the 4th dipole magnet of the synchrotron; the 42nd quadrupole magnet is connected to the transverse radio frequency field excitation device, and the 51st hexapole magnet and the 51st hexapole magnet are connected through the 1st convex track magnet The 51st quadrupole magnet and the 52nd quadrupole magnet are provided with the fifth dipole magnet of the synchrotron between the 51st quadrupole magnet and the 52nd quadrupole magnet, and the 52nd quadrupole magnet is connected to the second convex rail through a DC current detector Magnets, the 61st hexapole magnet, the 61st quadrupole magnet, the 62nd quadrupole magnet, the sixth dipole magnet of the synchrotron is arranged between the 61st quadrupole magnet and the 62nd quadrupole magnet; the 62nd quadrupole magnet Connect the first electrostatic deflection plate.

In the proton or heavy ion beam cancer treatment device, the connection is a vacuum tube beam connection, and the vacuum degree is 10 ^-9 -10 ^-11 mbar.

A method of using a proton or heavy ion beam cancer treatment device, the main steps of which are:

(1) The ion beam is generated by the ECR ion source, and the beam is drawn out at a high voltage of 20KV-40KV at the suction pole. After matching with the glasser lens, it is injected into the RF quadrupole linear accelerator for pre-acceleration or the RF quadrupole linear accelerator accelerates the ion to 2 -2.5MeV/u, then continue to be matched to the drift tube linear accelerator for acceleration, after the injection energy to reach the synchrotron is 4MeV/u-7MeV/u, after matching and transmission, the beam is distributed to the entrance of the synchrotron;

(2) After the beam reaches the entrance of the synchrotron, use the convex rail in the synchrotron to make the beam orbit in the ring protrude, so that the height of the convex rail is equivalent to the distance between the first electrostatic deflection plate of the synchrotron and the vacuum pipeline. When the beam fills the synchrotron for one circle, the height of the convex track begins to drop, and the falling time is 28-30 microseconds, which is equal to the number of input circles multiplied by the cyclotron period), so as to realize the multi-turn injection of the beam, and the number of injection circles is 15- 30 laps;

(3) After the beam is injected into the synchrotron, the beam is captured and accelerated by the high-frequency cavity. According to the treatment and experimental needs of the terminal, the beam is accelerated to a predetermined energy, which is 70-250 MeV for protons and 70-250 MeV for heavy ions. 100-400MeV/u; at the same time, gradually move the horizontal operating point of the beam to the vicinity of the 1/3 resonance line;

(4) After the beam reaches the predetermined energy, the hexapole iron current begins to increase, so that the stable phase space of the synchrotron is reduced to be greater than the emittance of the beam;

(5) When the transverse radio frequency excitation is turned on, the emittance of the beam increases under the action of the transverse electric field, thereby reaching the unstable region, and then the beam emittance increases rapidly along the boundary line of the unstable region, thereby reaching the electrostatic deflection plate was elicited;

(6) The extracted beam passes through the second electrostatic deflection plate and the second cutting magnet of the synchrotron, and then is transported to the high-energy beamline, and after being distributed by the high-energy beamline, it reaches the treatment or experiment terminal for related treatment or experiments.

(7) When the terminal effective dose reaches the preset value, the continued extraction of the beam can be stopped by stopping the effect of the transverse excitation.

The beneficial effects of the present invention are:

1. Using a synchrotron has greater advantages than using other devices.

The current mainstream accelerators are divided into three categories, namely linear accelerators, cyclotrons and synchrotrons. The transformation of the beam intensity can be achieved by using a linear accelerator, but the cost of a linear accelerator that accelerates the beam to the same energy is several times that of a synchrotron. Cyclotrons are relatively cheap, but cannot achieve rapid energy conversion. The use of synchrotrons can quickly change the energy and intensity of the extracted beam according to the needs of the terminal. Compared with cyclotrons and linear accelerators, it is simpler, more convenient, and more economical.

2. Using the linear accelerator as the design of the injector can obtain a higher injection flow intensity.

The biggest advantage of using a linear accelerator as an injector over a cyclotron as an injector is that the linear accelerator can provide a higher beam intensity (more than 20 times the beam intensity of the current SFC cyclotron at the Institute of Physics and Technology) and a smaller beam. emittance. The higher the injection current intensity, the more ions can be obtained by the synchrotron under the same number of injection cycles; the smaller the injection beam emittance, the more ions can be injected in the case of a smaller lateral aperture of the synchrotron. The number of turns, that is, more implanted ions are obtained. In this way, the transverse aperture of the synchrotron vacuum chamber can be saved, thereby reducing the cost of the synchrotron storage ring.

Description of the drawings:

Fig. 1 is a schematic front view of the present invention.

In the figure: ECR: electron cyclotron resonance ion source; RFQ: radio frequency quadrupole field accelerator; D: dipole iron; Q: quadrupole iron; S: hexapole iron; RF: high frequency accelerating cavity; DCCT: DC current detector ; ES: electrostatic deflection plate; MS: cutting magnet; KNO: transverse radio frequency field; Ion electron cyclotron resonance ion source); 1. Medium energy beamline; 2. Synchrotron; 3. High energy beamline; p_0Q1: the first galasser lens of the proton source beamline; p_0Q2: the second galasser lens of the proton source beamline; i_0Q1: the first galasser lens of the heavy ion source beamline; i_0Q2: the second galasser lens of the heavy ion source beamline; 0D1: the dipole magnet of the source beamline.

Detailed ways

The principles and features of the present invention are described below, and the examples given are only used to explain the present invention, and are not intended to limit the scope of the present invention.

Embodiment 1: See Fig. 1, a kind of proton beam cancer treatment device, comprises synchrotron 2, is provided with ion source 1 at the front end of synchrotron 2, and described ion source 1 is electron cyclotron resonance ion source p_ECR, electron cyclotron The resonant ion source is connected with the radio frequency quadrupole field linear accelerator through the glasser lens. The first two-pole magnet is arranged between the three quadrupole magnets, and the fourth four-pole magnet is connected to the first electrostatic deflection plate of the synchrotron 2 through the first cutting magnet; 31 high-energy beam lines 3 are drawn between the six-pole magnets.

The high-energy beamline 3 includes two lead-out terminals. Between the 22nd quadrupole magnet and the 31st hexapole magnet of the synchrotron 2, connect the 1st quadrupole magnet of the high-energy beamline, the 2nd quadrupole magnet of the high-energy beamline, and the 1st quadrupole magnet of the high-energy beamline through the 2nd cutting magnet. Dipole magnets; the first high-energy beamline and the second high-energy beamline are respectively drawn out by the first dipole magnet of the high-energy beamline, and the first high-energy beamline includes the first quadrupole magnet of the first high-energy beamline, the first high-energy beamline The sequence connection of the 2nd quadrupole magnet, the 3rd quadrupole magnet of the first high-energy beam line, the 4th quadrupole magnet of the first high-energy beam line; the second high-energy beam line includes the 1st quadrupole magnet of the second high-energy beam line, The sequence connection of elements such as the second quadrupole magnet of the second high-energy beamline, the third quadrupole magnet of the second high-energy beamline, and the fourth quadrupole magnet of the second high-energy beamline.

The synchrotron 2 includes a first electrostatic deflection plate connected to the 11th quadrupole magnet and the 12th quadrupole magnet, and the first dipole magnet of the synchrotron is arranged between the 11th quadrupole magnet and the 12th quadrupole magnet; The 12th quadrupole magnet is connected to the 2nd electrostatic deflection plate, the 21st quadrupole magnet, and the 22nd quadrupole magnet through the 3rd convex rail magnet, and the synchrotron 1st is provided between the 21st quadrupole magnet and the 22nd quadrupole magnet. 2 dipole magnets; the 22nd quadrupole magnet connects the 31st hexapole magnet and the 31st quadrupole magnet, the 32nd quadrupole magnet, the 41st quadrupole magnet, the 42nd quadrupole magnet, at the 31st quadrupole magnet and the 32nd The 3rd dipole magnet of the synchrotron is arranged between the quadrupole magnets, the high-frequency acceleration chamber of the synchrotron is arranged between the 32nd quadrupole magnet and the 41st quadrupole magnet, and the synchrotron high-frequency acceleration chamber is arranged between the 41st quadrupole magnet and the 42nd quadrupole magnet The 4th dipole magnet of the synchrotron is provided; the 42nd quadrupole magnet is connected to the transverse radio frequency field, and the 51st hexapole magnet, the 51st quadrupole magnet, and the 52nd quadrupole magnet are connected through the 1st convex rail magnet, and the 51st quadrupole magnet is connected to the 51st quadrupole magnet. The fifth second pole magnet of the synchrotron is arranged between the pole magnet and the 52nd quadrupole magnet. 62 quadrupole magnets, the sixth dipole magnet of the synchrotron is arranged between the 61st quadrupole magnet and the 62nd quadrupole magnet; the 62nd quadrupole magnet is connected to the first electrostatic deflection plate.

The connection described is a vacuum pipeline bundle connection, and the vacuum degree is 10 ^-9 -10 ^-10 mbar.

Embodiment 2: see Fig. 1, a proton beam cancer treatment device, a drift tube linear accelerator is set between the radio frequency quadrupole field accelerator and the first quadrupole magnet. All the other structures are the same as in Example 1.

Embodiment 3: A proton beam cancer treatment device, the high-energy beam line 3 includes more than two extraction terminals, according to the experiment and terminal needs, more high-energy beams can be continuously separated from the first or second high-energy beam line Wire. All the other structures are identical with embodiment 1 or embodiment 2.

Embodiment 4: A heavy ion beam cancer treatment device includes a synchrotron 2, and an ion source 1 is provided at the front end of the synchrotron 2. The ion source 1 is an electron cyclotron resonance ion source i_ECR, and an electron cyclotron resonance ion source Connect the 1st quadrupole magnet, the 2nd quadrupole magnet, the 3rd quadrupole magnet, the 4th quadrupole magnet with the radio frequency quadrupole field accelerator through the glasser lens, between the 2nd quadrupole magnet and the 3rd quadrupole magnet The 1st dipole magnet and the 4th quadrupole magnet are connected to the first electrostatic deflection plate of the synchrotron 2 through the 1st cutting magnet; beamline3.

The high-energy beamline 3 includes two lead-out terminals. Between the 22nd quadrupole magnet and the 31st hexapole magnet of the synchrotron 2, connect the 1st quadrupole magnet of the high-energy beamline, the 2nd quadrupole magnet of the high-energy beamline, and the 1st quadrupole magnet of the high-energy beamline through the 2nd cutting magnet. Dipole magnets; the first high-energy beamline and the second high-energy beamline are respectively drawn out by the first dipole magnet of the high-energy beamline, and the first high-energy beamline includes the first quadrupole magnet of the first high-energy beamline, the first high-energy beamline The sequence connection of the 2nd quadrupole magnet, the 3rd quadrupole magnet of the first high-energy beam line, the 4th quadrupole magnet of the first high-energy beam line; the second high-energy beam line includes the 1st quadrupole magnet of the second high-energy beam line, The second quadrupole magnet of the second high-energy beamline, the third quadrupole magnet of the second high-energy beamline, and the fourth quadrupole magnet of the second high-energy beamline are sequentially connected.

The synchrotron 2 includes a first electrostatic deflection plate connected to the 11th quadrupole magnet and the 12th quadrupole magnet, and the first dipole magnet of the synchrotron is arranged between the 11th quadrupole magnet and the 12th quadrupole magnet; The 12th quadrupole magnet is connected to the 2nd electrostatic deflection plate, the 21st quadrupole magnet, and the 22nd quadrupole magnet through the 3rd convex rail magnet, and the synchrotron 1st is provided between the 21st quadrupole magnet and the 22nd quadrupole magnet. 2 dipole magnets; the 22nd quadrupole magnet connects the 31st hexapole magnet and the 31st quadrupole magnet, the 32nd quadrupole magnet, the 41st quadrupole magnet, the 42nd quadrupole magnet, at the 31st quadrupole magnet and the 32nd The 3rd dipole magnet of the synchrotron is arranged between the quadrupole magnets, the high-frequency acceleration chamber of the synchrotron is arranged between the 32nd quadrupole magnet and the 41st quadrupole magnet, and the synchrotron high-frequency acceleration chamber is arranged between the 41st quadrupole magnet and the 42nd quadrupole magnet The 4th dipole magnet of the synchrotron is provided; the 42nd quadrupole magnet is connected to the transverse radio frequency field, and the 51st hexapole magnet, the 51st quadrupole magnet, and the 52nd quadrupole magnet are connected through the 1st convex rail magnet, and the 51st quadrupole magnet is connected to the 51st quadrupole magnet. The fifth second pole magnet of the synchrotron is arranged between the pole magnet and the 52nd quadrupole magnet. 62 quadrupole magnets, the sixth dipole magnet of the synchrotron is arranged between the 61st quadrupole magnet and the 62nd quadrupole magnet; the 62nd quadrupole magnet is connected to the first electrostatic deflection plate.

The connection described is a vacuum pipeline bundle connection, and the vacuum degree is ^{10-10-10-11 mbar} .

All the other structures are the same as in Example 1.

Embodiment 5: A heavy ion beam cancer treatment device, a drift tube linear accelerator is arranged between the radio frequency quadrupole field accelerator and the first quadrupole magnet. All the other structures are the same as in Example 4.

Embodiment 6: A heavy ion beam cancer treatment device, the high-energy beam line 3 includes more than two extraction terminals. All the other structures are identical with embodiment 4 or embodiment 5.

Embodiment 7: A method of using a proton beam cancer treatment device, the main steps of which are:

(1) The ion beam is generated by the ECR ion source, and the beam is drawn out at the high voltage of 20KV-40KV at the suction pole. After matching with the glasser lens, it is injected into the RF quadrupole linear accelerator for pre-acceleration, and the implanted energy of the synchrotron is 4MeV/u- After 7MeV/u, after matching and transmission, the beam is distributed to the entrance of the synchrotron;

(2) After the beam reaches the entrance of the synchrotron, use the convex rail in the synchrotron to make the beam orbit in the ring protrude, so that the height of the convex rail is equivalent to the distance between the first electrostatic deflection plate of the synchrotron and the vacuum pipeline. When the beam fills the synchrotron for one revolution, the height of the convex track gradually decreases, and the descending time is about 30 microseconds (approximately equal to the number of input circles multiplied by the cyclotron period), realizing multi-turn injection of the beam, and the number of injection circles is 15-30 lock up;

(3) After the beam is injected into the synchrotron, the beam is captured and accelerated by the high-frequency cavity. According to the treatment and experimental needs of the terminal, the beam is accelerated to a predetermined energy, which is 70-250 MeV for protons. At the same time, the beam The horizontal working point of the flow gradually moves to the vicinity of the 1/3 resonance line;

(4) After the beam reaches the predetermined energy, the hexapole iron current begins to increase, so that the stable phase space of the synchrotron is reduced to be greater than the emittance of the beam;

(5) When the transverse radio frequency excitation is turned on, the emittance of the beam increases under the action of the transverse electric field, thereby reaching the unstable region, and then the beam emittance increases rapidly along the boundary line of the unstable region, thereby reaching the electrostatic deflection plate was elicited;

(6) The extracted beam passes through the second electrostatic deflection plate and the second cutting magnet of the synchrotron, and then is transported to the high-energy beamline, and after being distributed by the high-energy beamline, it reaches the treatment or experiment terminal for related treatment or experiments.

(7) When the terminal effective dose reaches the preset value, the continued extraction of the beam can be stopped by stopping the effect of the transverse excitation.

Example 8: A method of using a proton beam cancer treatment device, the main step (1) is to generate ion beams from the ECR ion source, extract the beam current at a high voltage of 20KV-40KV, and inject it into the Radio frequency quadrupole linear accelerator, the radio frequency quadrupole linear accelerator accelerates ions to 2-2.5MeV/u, and then continues to match to the drift tube linear accelerator for acceleration, after reaching the injection energy of the synchrotron 4MeV/u-7MeV/u, and then passing through Matching and delivery to distribute the beam to the synchrotron entrance. All the other steps are the same as in Example 7.

Taking the HIRFL device of the Institute of Near Objects as an example, the current C6+ flow intensity of the fan-shaped cyclotron SFC is about 15uA, the horizontal emittance is about 25pi mm mrad, and the lateral horizontal acceptance of the synchrotron CSRm is 200pi mm mrad. Inject the highest current intensity of about 100uA. If a linear accelerator is used as the injector: the extraction current intensity of the linear accelerator is 200uA, and the horizontal emittance is 6-12pi mm mrad, then the injection current intensity is on the order of milliamps.

Embodiment 9: A method of using a heavy ion beam cancer treatment device, the main steps of which are:

(1) The ion beam is generated by the ECR ion source, and the beam is drawn out at the high voltage of 20KV-40KV at the suction pole. After matching with the glasser lens, it is injected into the RF quadrupole linear accelerator for acceleration, and the implanted energy reaching the synchrotron is 2-4MeV/u , and then through matching and transmission, the beam is delivered to the entrance of the synchrotron;

(2) After the beam reaches the entrance of the synchrotron, use the convex rail in the synchrotron to make the beam orbit in the ring protrude, so that the height of the convex rail is equivalent to the distance between the first electrostatic deflection plate of the synchrotron and the vacuum pipeline. When the beam fills the synchrotron for one revolution, the height of the convex track gradually decreases, and the descending time is about 30 microseconds (approximately equal to the number of input circles multiplied by the cyclotron period), realizing multi-turn injection of the beam, and the number of injection circles is 15-30 lock up;

(3) After the beam is injected into the synchrotron, the beam is captured and accelerated through the high-frequency cavity, and the beam is accelerated to a predetermined energy according to the treatment and experimental needs of the terminal, which is 100-400MeV/u for heavy ions; at the same time , gradually move the horizontal working point of the beam to the vicinity of the 1/3 resonance line;

(4) After the beam reaches the predetermined energy, the hexapole iron current begins to increase, so that the stable phase space of the synchrotron is reduced to be greater than the emittance of the beam;

(5) When the transverse radio frequency excitation is turned on, the emittance of the beam increases under the action of the transverse electric field, thereby reaching the unstable region, and then the beam emittance increases rapidly along the boundary line of the unstable region, thereby reaching the electrostatic deflection plate was elicited;

(6) The extracted beam passes through the second electrostatic deflection plate and the second cutting magnet of the synchrotron, and then is transported to the high-energy beamline, and after being distributed by the high-energy beamline, it reaches the treatment or experiment terminal for related treatment or experiments.

(7) When the terminal effective dose reaches the preset value, the continued extraction of the beam can be stopped by stopping the effect of the transverse excitation.

Example 10: A method of using a heavy ion beam cancer treatment device, the main step (1) is to generate an ion beam from an ECR ion source, extract the beam current at a high voltage of 20KV-40KV, and inject it after being matched by a glasser lens To the radio frequency quadrupole linear accelerator, the radio frequency quadrupole linear accelerator accelerates the ions to 2-2.5MeV/u, and then continues to match to the drift tube linear accelerator for acceleration, after reaching the injection energy of the synchrotron 4MeV/u-7MeV/u, then After matching and transmission, the beam is delivered to the entrance of the synchrotron. All the other steps are the same as in Example 9.

The above descriptions are only preferred embodiments of the present invention, and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principles of the present invention shall be included in the protection of the present invention. within range.

Claims (6)

1. a kind of proton or cancer Therapy with Heavy Ion Beams device, include synchrotron, it is characterized in that being provided with ion source in the front end of synchrotron, described ion source is Electron cyclotron resonance ion source, Electron cyclotron resonance ion source is by the 0Q01 glasser lens on the bunch of source and 0Q02 glasser lens, 1 two pole ferrum connects radio frequency four polar field linear accelerator, the 1st quadrupole electromagnet on middle energy bunch, 2nd quadrupole electromagnet, 3rd quadrupole electromagnet, 4th quadrupole electromagnet, the 1st dipolar magnet is provided with between the 2nd quadrupole electromagnet and the 3rd quadrupole electromagnet, 4th quadrupole electromagnet connects the 1st electrostatic deflection plates of synchrotron by the 1st septum magnet, high energy bunch is drawn between the 22nd quadrupole electromagnet and the 31st six pole magnet of described synchrotron, described synchrotron includes the 1st electrostatic deflection plates between the 11st quadrupole electromagnet, the 62nd quadrupole electromagnet, is provided with synchrotron the 1st dipolar magnet between the 11st quadrupole electromagnet and the 12nd quadrupole electromagnet, 12nd quadrupole electromagnet is connected the 2nd electrostatic deflection plates by the 3rd bumper magnet, is connected the 21st quadrupole electromagnet, the 22nd quadrupole electromagnet, is provided with synchrotron the 2nd dipolar magnet between the 21st quadrupole electromagnet and the 22nd quadrupole electromagnet, 22nd quadrupole electromagnet connects the 31st six pole magnet and the 31st quadrupole electromagnet, the 32nd quadrupole electromagnet, the 41st quadrupole electromagnet, the 42nd quadrupole electromagnet, synchrotron the 3rd dipolar magnet is provided with between the 31st quadrupole electromagnet and the 32nd quadrupole electromagnet, between the 32nd quadrupole electromagnet and the 41st quadrupole electromagnet, be provided with synchrotron radio-frequency acceleration cavity, be provided with synchrotron the 4th dipolar magnet at the 41st quadrupole electromagnet and the 42nd quadrupole electromagnet, 42nd quadrupole electromagnet connects horizontal radio-frequency field exciting bank, and connect the 51st six pole magnet and the 51st quadrupole electromagnet, the 52nd quadrupole electromagnet by the 1st bumper magnet, synchrotron the 5th dipolar magnet is provided with between the 51st quadrupole electromagnet and the 52nd quadrupole electromagnet, 52nd quadrupole electromagnet connects the 2nd bumper magnet, the 61st six pole magnet, the 61st quadrupole electromagnet, the 62nd quadrupole electromagnet by DC current detector, synchrotron the 6th dipolar magnet is provided with between the 61st quadrupole electromagnet and the 62nd quadrupole electromagnet, 62nd quadrupole electromagnet connects the 1st electrostatic deflection plates.

2. proton as claimed in claim 1 or cancer Therapy with Heavy Ion Beams device, characterized by further comprising and be provided with draft tube linac between described radio frequency four polar field linear accelerator and the 1st quadrupole electromagnet.

3. proton as claimed in claim 1 or cancer Therapy with Heavy Ion Beams device, characterized by further comprising described high energy bunch and include multiple extraction terminal.

4. proton as claimed in claim 3 or cancer Therapy with Heavy Ion Beams device, is characterized in that described high energy bunch includes and be connected high energy bunch 1st quadrupole electromagnet, high energy bunch 2nd quadrupole electromagnet, high energy bunch 1st dipolar magnet with between the 31st six pole magnet by the 2nd septum magnet at the 22nd quadrupole electromagnet of described synchrotron; Draw the first high energy bunch and the second high energy bunch respectively by high energy bunch the 1st dipolar magnet, the first high energy bunch includes the first high energy bunch the 1st quadrupole electromagnet, the first high energy bunch the 2nd quadrupole electromagnet, the first high energy bunch the 3rd quadrupole electromagnet, being linked in sequence of the first high energy bunch the 4th quadrupole electromagnet; Second high energy bunch includes the second high energy bunch the 1st quadrupole electromagnet, the second high energy bunch the 2nd quadrupole electromagnet, the second high energy bunch the 3rd quadrupole electromagnet, being linked in sequence of the second high energy bunch the 4th quadrupole electromagnet.

5. the proton as described in as arbitrary in Claims 1-4 or cancer Therapy with Heavy Ion Beams device, it is characterized in that described connection is that vacuum pipe line connects, vacuum is 10 ^-9-10 ^-11mbar.

6. use a method for proton or cancer Therapy with Heavy Ion Beams device, it is characterized in that step is:

(1) ion beam is produced by ecr ion source, under extraction electrode high pressure 20KV-40KV, line is drawn, after the coupling of glasser lens, be injected into radio frequency quadrupole linac carry out preaceleration or radio frequency quadrupole linac by acceleration of ions to 2-2.5MeV/u, then continue to match draft tube linac to accelerate, the Implantation Energy arriving synchrotron is after 4MeV/u-7MeV/u, again through overmatching and transmission, by beam delivery to synchrotron entrance;

(2), after line arrives synchrotron entrance, utilize the protruding rail in synchrotron to make ring internal beam current track protruding, make protruding rail height suitable from the distance of vacuum pipe with synchrotron first electrostatic deflection plates; After line fills synchrotron one circle, protruding rail height starts to decline, and fall time is 28-30 microsecond, equals the input number of turns and is multiplied by the convolution cycle, and to realize the multi-turn injection of line, injecting the number of turns is 15-30 circle;

(3) after line is injected into synchrotron, undertaken capturing and accelerating by frequency cavity halved tie stream, according to treatment and the experiment needs of terminal, by beam acceleration to predetermined power, being 70-250MeV for proton, is 100-400MeV/u for heavy ion; Meanwhile, the horizontal operation of line point is progressively moved near 1/3 resonance line;

(4), after line arrives predetermined power, the ferroelectric stream of six types of severe debility disease starts to increase, and makes the stable phase space of synchrotron narrow down to the emittance being greater than line;

(5) open horizontal radio-frequency (RF) excited, line is under the effect of transverse electric field, and emittance increases, thus arrives range of instability, and beam emittance increases rapidly along the demarcation line of range of instability then, thus arrival electrostatic deflection plates is drawn;

(6) ejected beam is through the 2nd electrostatic deflection plates of synchrotron and the 2nd septum magnet, is transported to high energy bunch, through the dispensing of high energy bunch, arrives treatment or experimental terminal, carries out associated treatment or experiment;

(7), when terminal effective dose reaches preset value, can draw by stopping the continuation of line that is used for stopping of transversely excited.