CN108243551A - The proton-synchrotron that a kind of combined magnet is formed - Google Patents
The proton-synchrotron that a kind of combined magnet is formed Download PDFInfo
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- CN108243551A CN108243551A CN201810071320.4A CN201810071320A CN108243551A CN 108243551 A CN108243551 A CN 108243551A CN 201810071320 A CN201810071320 A CN 201810071320A CN 108243551 A CN108243551 A CN 108243551A
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- combined magnet
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- quadrupole
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- 238000002347 injection Methods 0.000 claims description 15
- 239000007924 injection Substances 0.000 claims description 15
- 238000005520 cutting process Methods 0.000 claims description 11
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 9
- 238000000605 extraction Methods 0.000 claims description 8
- 229910052742 iron Inorganic materials 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 238000003860 storage Methods 0.000 abstract description 4
- 238000005452 bending Methods 0.000 abstract description 2
- 235000000396 iron Nutrition 0.000 abstract description 2
- BGPVFRJUHWVFKM-UHFFFAOYSA-N N1=C2C=CC=CC2=[N+]([O-])C1(CC1)CCC21N=C1C=CC=CC1=[N+]2[O-] Chemical compound N1=C2C=CC=CC2=[N+]([O-])C1(CC1)CCC21N=C1C=CC=CC1=[N+]2[O-] BGPVFRJUHWVFKM-UHFFFAOYSA-N 0.000 description 6
- 238000010276 construction Methods 0.000 description 3
- 238000010586 diagram Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 2
- 241000209094 Oryza Species 0.000 description 2
- 235000007164 Oryza sativa Nutrition 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 230000005284 excitation Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000005086 pumping Methods 0.000 description 2
- 230000005855 radiation Effects 0.000 description 2
- 235000009566 rice Nutrition 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 230000009471 action Effects 0.000 description 1
- 238000004364 calculation method Methods 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000001064 degrader Substances 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000004146 energy storage Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 150000002500 ions Chemical class 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000001959 radiotherapy Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 230000011218 segmentation Effects 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 230000002463 transducing effect Effects 0.000 description 1
Classifications
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H13/00—Magnetic resonance accelerators; Cyclotrons
- H05H13/04—Synchrotrons
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H2277/00—Applications of particle accelerators
- H05H2277/10—Medical devices
- H05H2277/11—Radiotherapy
Abstract
The present invention relates to the proton-synchrotron that a kind of combined magnet is formed, including forming four of loop configuration deflection combined magnets by four straight sections connections, it is described deflection combined magnet be have both deflection dipolar magnet and horizontal focusing, the combined magnet of horizontal defocus quadrupole electromagnet function, the straight sections include the four sextupole combined magnets with horizontal focusing or horizontal defocus.By the way that two pole combined magnet of quadrupole and quadrupole sextupole combined magnet are used on medical proton precessional magnetometer for the first time, loopful envelope function is controlled in smaller level, the acceptance of synchrotron and proton storage number are effectively increased, improves proton utilization rate and duty ratio, shortens treatment time；In addition, the use of combined magnet and four pieces of bending irons reduces magnet device and the gap between them, utilization component number as few as possible realizes the function of medical accelerator, so as to reduce synchrotron the space occupied, reduces equipment cost and treatment cost.
Description
Technical field
The present invention relates to the matter that the synchrotron field for oncotherapy more particularly to a kind of combined magnet are formed
Sub- synchrotron.
Background technology
Excellent Bragg peak character causes it to become means the most advanced in oncotherapy to proton in the depth direction
One of, the construction of proton therapeutic appts and therapeutic community is more and more in the world at present.Proton in operation at present and construction is controlled
Cancer accelerator is mainly cyclotron and synchrotron.
Cyclotron can provide stable continuous beam, and line cut-out and opening speed quickly, can meet breathing
The requirement of gate.But cyclotron change energy dependence is the mechanical device being placed on high energy line --- degrader,
Beam energy is reduced using scattering；Its advantage is that energy adjustment is rapid, can realize 50 milliseconds one grade of change energy velocity,
Quick multiple scanning pattern can be supported to treat mobile tumour；But shortcoming is that scattering causes line utilization rate very low, during treatment
During minimum energy 70MeV by efficiency less than 1%, a large amount of lines damages caused by scattering caused by dropping energy and energy selection later
Mistake can cause greatly to radiate, and very big pressure is caused to radiation protection and equipment safety.
Compared with cyclotron, the obvious advantage of synchrotron is that it can easily carry out the energy of line
It adjusts, to adapt to the needs that radiotherapy accurately changes ion energy, does not need to additional energy drop energy piece, it can be ensured that phase
To the environment of clean (radiation is small).After employing new multipotency amount lead-out mode, the intrinsic transducing time is slow, causes nothing
The shortcomings that imitating treatment time length and can not adapting to quick multiple scanning is substantially not present.
Have patent document CN105392270A when specific magnet, power supply are when designs, consider above-mentioned this new technology,
Treatment time so as to greatly reduce.But the design one of this accelerator is complex, employs 8 pieces of deflection dipolar magnets
Quadrupole electromagnet is focused on and defocused with 12 pieces, and the increase of element means the decline of reliability；Second is that structure is not compact enough, element with
Gap between element is into waste；Third, magnetic field intensity is very high, close to saturation, excitation efficiency is not high, causes energy consumption higher, magnetic
Iron is powerful device, and the liter of cycle can drop energy process and waste big energy.
Invention content
In order to solve the above-mentioned problems of the prior art, the present invention is intended to provide the proton that a kind of combined magnet is formed
Synchrotron.
The proton-synchrotron that combined magnet of the present invention is formed, including being connected by four straight sections with shape
Four deflection combined magnets of structure are circularized, the deflection combined magnet is has both deflection dipolar magnet and horizontal focusing, water
The flat two four-electrode pattern magnet for defocusing quadrupole electromagnet function, the straight sections include having the function of horizontal focusing or horizontal defocus
Four sextupole combined magnets.
The deflection combined magnet deflects combined magnet for first, second, third and fourth, wherein, the first deflection combination
Magnet and the second deflection combined magnet are connected, and the second deflection combined magnet is connected with third deflection combined magnet, third deflection group
It closes magnet and quadrupole deflector combined magnet is connected, quadrupole deflector combined magnet also is connected to form one with the first deflection combined magnet
Loop configuration.
The four sextupoles combined magnet includes first, second, third and fourth horizontal defocus quadrupole and sextupole combined magnet,
Wherein, first level defocus quadrupole and sextupole combined magnet be connected to the first deflection combined magnet and the second deflection combined magnet it
Between, the second horizontal defocus quadrupole and sextupole combined magnet be connected to the second deflection combined magnet and third deflection combined magnet it
Between, third horizontal defocus quadrupole and sextupole combined magnet be connected to third deflection combined magnet and quadrupole deflector combined magnet it
Between, the 4th horizontal defocus quadrupole and sextupole combined magnet be connected to quadrupole deflector combined magnet and the first deflection combined magnet it
Between.
It is connected with high frequency accelerator, the first injection between first deflection combined magnet and the second deflection combined magnet in turn
Bumper magnet, lateral high frequency pumping electrode and first level defocus quadrupole and sextupole combined magnet.
The second horizontal defocus quadrupole and six are connected in turn between second deflection combined magnet and third deflection combined magnet
Pole combined magnet and extraction electrostatic cutting plate.
Third, which deflects, is connected with the second injection bump magnet and the in turn between combined magnet and quadrupole deflector combined magnet
Three horizontal defocus quadrupoles and sextupole combined magnet.
Third deflection combined magnet is connected with the magnetostatic septum magnet of the first extraction and second in turn and draws magnetostatic septum magnet.
The 4th horizontal defocus quadrupole and six are connected in turn between quadrupole deflector combined magnet and the first deflection combined magnet
Pole combined magnet and injection electrostatic cutting plate.
Injection electrostatic cutting plate is connected with the magnetostatic septum magnet of injection.
The deflection combined magnet is segmentation structure, is formed as the deflection magnet with gradient.
By the present invention in that deflection combined magnet has both deflection dipolar magnet and horizontal focusing, horizontal defocus quadrupole electromagnet work(
Can, control its horizontal and vertical envelope function that in smaller level, combined magnet all is deflected by design so as to reach double-directional focusing
The intensity of possessed Quadrupole component, can in weak focus (operating point be less than 1) and strong-focusing, (operating point be big by working point control
In 1).Strong-focusing can improve tolerance of the line to magnetic field and installation equal error.Due to just being secured in design and manufacture
Every piece of Quadrupole component intensity for having of deflection combined magnet, error and design in manufacturing process it is imperfect can cause it is Bu Tong inclined
Turn the relative intensity (Quadrupole component intensity/deflection dipolar magnet intensity) of possessed Quadrupole component under combined magnet intensity no
Together, it and can not be adjusted, this just needs some additional quadrupole electromagnets to carry out work point calibration and carries out operating point shifting
It is dynamic.In addition, synchrotron, which also needs to six pole magnet, carries out resonant excitation and chromaticity correction.It will correction quadrupole electromagnet and sextupole magnetic
Iron is combined into quadrupole sextupole combined magnet so that function also contributes to the optimization of structure there are two types of identity element tools.With patent document
CN105392270A is compared, envelope function smaller of the invention, and then effectively increases the acceptance of synchrotron, is increased
Proton storage number improves proton utilization rate and duty ratio, shortens treatment time；Small envelope function means smaller
Magnet aperture and small magnet energy storage, also reduce energy expenditure；Also the perimeter of entire accelerator is reduced, and then farthest
The construction cost of device and building is reduced, reduces treatment cost.In addition, the structure of the present invention is closely, reducing need not
The gap wanted and magnet device, to realize the function of medical accelerator using component number as few as possible.In short, the present invention is logical
After using two pole combined magnet of quadrupole and quadrupole sextupole combined magnet on medical proton precessional magnetometer for the first time, by loopful envelope function
Control effectively increases the acceptance of synchrotron and proton storage number in smaller level, improve proton utilization rate and
Duty ratio shortens treatment time；In addition, the use of combined magnet and four pieces of bending irons reduce magnet device and they between
Gap, utilization component number as few as possible realizes the function of medical accelerator, so as to reduce synchrotron the space occupied,
Reduce equipment cost and treatment cost.
Description of the drawings
Fig. 1 is the structure of proton-synchrotron that combined magnet according to a preferred embodiment of the present invention is formed
Schematic diagram；
Fig. 2 is the schematic diagram of the envelope function of medical proton-synchrotron that the combined magnet of Fig. 1 is formed；
Fig. 3 is the schematic diagram of deflection combined magnet according to a further advantageous embodiment of the invention.
Specific embodiment
1-3 below in conjunction with the accompanying drawings provides the preferred embodiment of the present invention, and is described in detail.
As shown in Figure 1, the proton-synchrotron that combined magnet according to the present invention is formed includes first, second, the
Three and quadrupole deflector combined magnet 1,2,3,4, wherein, the first deflection combined magnet 1 deflects combined magnet 2 with second and is connected, the
Two deflection combined magnets 2 are connected with third deflection combined magnet 3, third deflection combined magnet 3 and 4 phase of quadrupole deflector combined magnet
Even, quadrupole deflector combined magnet 4 is connected to form a loop configuration with deflected beam (line side with the first deflection combined magnet 1
The clockwise direction of loop configuration in for Fig. 1).Wherein, first, second, third and fourth deflection combined magnet 1,2,3,4 is equal
The combined magnet for being 90 degree for deflection angle has deflection dipolar magnet, horizontal focusing and horizontal defocus quadrupole magnetic simultaneously
Iron function.Specifically, first, second, third and fourth deflection combined magnet 1,2,3,4 is made of two parts, is had per part
There is scheduled varying strength Quadrupole component, be respectively provided with horizontal defocus and horizontal focusing effect, form two pole four-electrode pattern type magnetic
Iron.
Proton-synchrotron further includes first straight line section, second straight line section, third straight sections and the 4th straight sections, wherein
First straight line section is connected between the first deflection combined magnet 1 and the second deflection combined magnet 2, and second straight line section is connected to second
It deflects between combined magnet 2 and third deflection combined magnet 3, third straight sections are connected to third deflection combined magnet 3 and the 4th
Between deflecting combined magnet 4, the 4th straight sections are connected between the deflection combined magnet 1 of quadrupole deflector combined magnet 4 and first.
First straight line section includes the height being connected in turn between the first deflection combined magnet 1 and the second deflection combined magnet 2
Frequency accelerator 41, the first injection bump magnet 13, lateral high frequency pumping electrode 31 and first level defocus quadrupole and sextupole
Combined magnet 21.
Second straight line section includes be connected in turn between the second deflection combined magnet 2 and third deflection combined magnet 3 the
Two horizontal defocus quadrupoles and sextupole combined magnet 22 and extraction electrostatic cutting plate 32.
Third straight sections include be connected in turn between third deflection combined magnet 3 and quadrupole deflector combined magnet 4 the
Two injection bump magnet 14 and third horizontal defocus quadrupole and sextupole combined magnet 23.In addition, third straight sections further include with
Third deflection combined magnet 3 sequentially connected first draws magnetostatic septum magnet 33 and second and draws magnetostatic septum magnet 34.
4th straight sections include being connected to the 4th water that quadrupole deflector combined magnet 4 and first deflects combined magnet 1 in turn
It is flat to defocus quadrupole and sextupole combined magnet 24 and injection electrostatic cutting plate 12.In addition, the 4th straight sections further include with inject it is quiet
The magnetostatic septum magnet 11 of injection that electric cutting plate 12 connects.
Wherein, first, second, third and fourth horizontal defocus quadrupole has simultaneously with sextupole combined magnet 21,22,23,24
There are horizontal defocus quadrupole electromagnet and horizontal defocus six pole magnet function, form quadrupole sextupole combined magnet.Specifically, first,
2nd, the third and fourth horizontal defocus quadrupole has set 6 pole component with sextupole combined magnet 21,22,23,24, is respectively provided with
Resonance six pole magnet and the effect of chromaticity six pole magnet, form quadrupole sextupole combined magnet.
It should be understood that first, second, third and fourth horizontal defocus quadrupole also may be used with sextupole combined magnet 21,22,23,24
To replace with first, second, third and fourth horizontal focusing quadrupole and sextupole combined magnet.
It is connected between above-mentioned each component by vacuum tube (not shown).
In actual use, low energy proton beam is provided by injecting magnetostatic septum magnet by injector in a treatment cycle
11st, injection electrostatic cutting plate 12, the first and second injection bump magnet 13,14 and first, second, third and fourth deflection
Combined magnet 1,2,3,4 is injected into the medical proton-synchrotron of the combined magnet composition of the present invention and forms storage；So
Afterwards, it is required according to treatment, passes through the synchronous field strength for rising first, second, third and fourth and deflecting combined magnet 1,2,3,4, matter
Son energy under the action of high frequency accelerator 41 gets a promotion.In the energy of corresponding treatment, first, second, third He is encouraged
4th horizontal defocus quadrupole and sextupole combined magnet 21,22,23,24, mobile working point are laterally swashing to close to third order resonance line
It encourages and is diffused under electrode 31, first, 6 pole component effect possessed by third horizontal defocus quadrupole and sextupole combined magnet 21,23
Extraction channel is drawn out to proton synchrotron by the extraction extraction electrostatic of electrostatic cutting plate 32 and first, second septum magnet 33,34 and adds
Fast device is outer until patient.When needed, it can stop drawing in treatment cycle, and switch energy and implement to draw.
Fig. 2 is the horizontal and vertical line envelope function of the present invention, wherein, the size of ordinate representative function, unit is
Rice (m), abscissa represent the lengthwise position in synchrotron, and unit is rice (m).As it can be seen that the present invention has envelope function
It is small, it the characteristics of effective acceptance is big, simulates calculation shows that more protons can be stored.
In the present embodiment, quadrupole deflector combined magnet 4 is two-part structure, and every section of all level with varying strength dissipates
Burnt or horizontal focusing Quadrupole component, is formed as the deflection magnet with gradient.In fact, quadrupole deflector combined magnet 40 can also root
According to needing to be formed as three stage structure, as shown in Figure 3.It should be understood that first, second, third and fourth deflection according to the present invention
Combined magnet 1,2,3,4 can be designed as needed.
To sum up, forming double-directional focusing present invention employs 4 blocks of combined deflection magnets reduces envelope function and shortening week
It is long, and 4 pieces of quadrupole sextupole combined magnets can be completed to adjust operating point and encourage third order resonance work simultaneously.Such structure
Number of elements is greatly reduced, while for the flexibility for ensureing certain adjusting.
Above, only presently preferred embodiments of the present invention is not limited to the scope of the present invention, above-mentioned reality of the invention
Applying example can also make a variety of changes.
The above embodiment of the present invention can also make a variety of changes.I.e. every claims applied according to the present invention
And simple, the equivalent changes and modifications that description is made, fall within the claims of patent of the present invention.This hair
Bright not detailed description is routine techniques content.
Claims (10)
1. the proton-synchrotron that a kind of combined magnet is formed, which is characterized in that proton-synchrotron is included by four
A straight sections connection is to form four of loop configuration deflection combined magnets, and the deflection combined magnet is has both two pole magnetic of deflection
Iron and horizontal focusing, two four-electrode pattern magnet of horizontal defocus quadrupole electromagnet function, the straight sections are included with horizontal focusing
Burnt or horizontal defocus function four sextupole combined magnets.
2. proton-synchrotron according to claim 1, which is characterized in that the deflection combined magnet is first, the
2nd, the third and fourth deflection combined magnet (1,2,3,4), wherein, the first deflection combined magnet (1) and the second deflection combined magnet
(2) it is connected, the second deflection combined magnet (2) and third deflection combined magnet (3) are connected, and third deflects combined magnet (3) and the
Quadrupole deflector combined magnet (4) is connected, and quadrupole deflector combined magnet (4) also is connected to form one with the first deflection combined magnet (1)
Loop configuration.
3. proton-synchrotron according to claim 2, which is characterized in that the four sextupoles combined magnet includes the
First, second, third and the 4th horizontal defocus quadrupole and sextupole combined magnet (21,22,23,24), wherein, first level defocuses four
Pole and sextupole combined magnet (21) are connected between the first deflection combined magnet (1) and the second deflection combined magnet (2), the second water
It is flat defocus quadrupole and sextupole combined magnet (22) be connected to the second deflection combined magnet (2) and third deflect combined magnet (3) it
Between, third horizontal defocus quadrupole is connected to third deflection combined magnet (3) with sextupole combined magnet (23) and quadrupole deflector combines
Between magnet (4), the 4th horizontal defocus quadrupole is connected to quadrupole deflector combined magnet (4) and first with sextupole combined magnet (24)
Between deflection combined magnet (1).
4. proton-synchrotron according to claim 3, which is characterized in that the first deflection combined magnet (1) and second
High frequency accelerator (41), the first injection bump magnet (13), lateral high frequency is connected between deflection combined magnet (2) in turn to swash
It encourages electrode (31) and first level defocuses quadrupole and sextupole combined magnet (21).
5. proton-synchrotron according to claim 3, which is characterized in that the second deflection combined magnet (2) and third
It is connected with the second horizontal defocus quadrupole and sextupole combined magnet (22) and extraction electrostatic cutting between deflection combined magnet (3) in turn
Plate (32).
6. proton-synchrotron according to claim 3, which is characterized in that third deflection combined magnet (3) and the 4th
The second injection bump magnet (14) is connected in turn between deflection combined magnet (4) and third horizontal defocus quadrupole is combined with sextupole
Magnet (23).
7. proton-synchrotron according to claim 6, which is characterized in that third deflection combined magnet (3) connects successively
It is connected to the magnetostatic septum magnet of the first extraction (33) and second and draws magnetostatic septum magnet (34).
8. proton-synchrotron according to claim 3, which is characterized in that quadrupole deflector combined magnet (4) and first
It is connected with the 4th horizontal defocus quadrupole and sextupole combined magnet (24) and injection electrostatic cutting between deflection combined magnet (1) in turn
Plate (12).
9. proton-synchrotron according to claim 8, which is characterized in that injection electrostatic cutting plate (12) is connected with note
Enter magnetostatic septum magnet (11).
10. proton-synchrotron according to claim 1, which is characterized in that the deflection combined magnet is segmented
Structure is formed as the deflection magnet with gradient.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810071320.4A CN108243551A (en) | 2018-01-25 | 2018-01-25 | The proton-synchrotron that a kind of combined magnet is formed |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810071320.4A CN108243551A (en) | 2018-01-25 | 2018-01-25 | The proton-synchrotron that a kind of combined magnet is formed |
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| Publication Number | Publication Date |
|---|---|
| CN108243551A true CN108243551A (en) | 2018-07-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810071320.4A Pending CN108243551A (en) | 2018-01-25 | 2018-01-25 | The proton-synchrotron that a kind of combined magnet is formed |
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| Country | Link |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109842986A (en) * | 2019-02-02 | 2019-06-04 | 惠州离子科学研究中心 | The uniform fast-cycling synchrotron of lateral line and accelerator system |
| CN111249633A (en) * | 2020-03-21 | 2020-06-09 | 华中科技大学 | High momentum acceptance superconducting rotating gantry for proton therapy |
| CN113382530A (en) * | 2021-07-22 | 2021-09-10 | 中国科学院上海高等研究院 | Medical proton synchrotron of super high dose rate |
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|---|---|---|---|---|
| CN109842986A (en) * | 2019-02-02 | 2019-06-04 | 惠州离子科学研究中心 | The uniform fast-cycling synchrotron of lateral line and accelerator system |
| CN111249633A (en) * | 2020-03-21 | 2020-06-09 | 华中科技大学 | High momentum acceptance superconducting rotating gantry for proton therapy |
| CN113382530A (en) * | 2021-07-22 | 2021-09-10 | 中国科学院上海高等研究院 | Medical proton synchrotron of super high dose rate |
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