CN102772646A - Medicine for treating respiratory distress syndrome and preparation method thereof - Google Patents
Medicine for treating respiratory distress syndrome and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a medicine for treating a respiratory distress syndrome and a preparation method of the medicine. The medicine is prepared by seven traditional Chinese medicines, such as folium mori, dock root radix rumicis, vitex negundo, rhizoma atractylodis, peppermint, radix ophiopogonis and radix scutellariae. The medicine provided by the invention has the effects of eliminating phlegm by cooling, freeing lung and relieving asthma, tonifying qi and yin, and warming heart and kidney, thereby having a good treatment effect for respiratory distress syndrome without toxic and side effects; and synchronously, the modes of administration of the medicine are multiple and the medicine is capable of being taken orally and treated externally, thereby providing another best choice for the administration of the respiratory distress syndrome. In addition, the medicine provided by the invention has a certain effect for treating acute and chronic respiratory failures.
Description
Technical field
The present invention relates to a kind of medicine of treating respiratory distress syndrome and preparation method thereof, belong to Chinese herbal medicine and preparation method thereof.
Background technology
Respiratory distress syndrome (acute respiratory distress syndrome; ARDS) branch of broad sense and narrow sense; The former refers to all respiratory distress symptoms that occurs; No matter its cause of disease can this be named, the latter refers to lack respiratory distress syndrome (ivrds) (RDS) or the respiratory distress syndrome (HMD) that pulmonary surfactant causes.The narrow sense respiratory distress syndrome mainly comprises adult respiratory distress syndrome and hyaline membrane disease of newborn; What be meant the inside and outside attack of lungs such as severe infections, wound, shock back appearance serves as the main clinical syndrome that shows with the damage of alveolar blood capillary, and what belong to acute lung injury is serious stage or type.No matter pulmonary surfactant lacks due to which kind of reason, can cause severe respiratory failure, and be born back first day morbidity and the cause of death of premature infant mainly is respiratory distress syndrome, and can bring secular breathing and neural sequela.
Though its cause of disease is different, the pathology and the changing function of lung tissue damage are roughly the same, and clinical manifestation is acute respiratory distress; Refractory hypoxemia, because of poverty-stricken the levying of its clinical similar infant breathes, and their cause of disease and pathogenesis are not quite similar; So satisfy titled with " adult ", to show difference.Ashbauth in 1972 propose the name of adult respiratory distress syndrome (adult respiratory distress syndrome).Notice that now intrinsic also betides the child, so collaborative discussion of American-European scholar reached common understanding, replace adult (adult) with acute (acute), be called adult respiratory distress syndrome, abbreviation is still ARDS.Primary disease mostly occurs in the health adult of original no obvious pulmonary disease, causes the lung compliance forfeiture that causes behind the acute pulmonary lesion, wellability pathological changes in the diffusivity lung in multiple lung internal and external factor.Simultaneously, child and neonatal sickness rate are also higher.
Its Clinical symptoms of respiratory distress syndrome (ivrds) shows as breathes speed and poverty-stricken frequently, carrying out property hypoxemia, and the X line presents the diffusivity alveolar and soaks into, and typical respiratory distress syndrome often presents stage.The first phase: be the wound revival phase, Respiratory symptoms is not obvious, or post-traumatic reactive tachypnea is only arranged.The second phase: engender rapid breathing, uncomfortable in chest, livid purple.But physical examination and the inspection of X-ray pulmonary are not unusual.In time treatment is expected rapid recovery.The third phase: show as the respiratory distress and livid purple of carrying out property, can not correct even suck high-concentration oxygen.The fourth phase: be the depletion of ventilating, severe depletion of oxygen and carbon dioxide retention are arranged, merge acidosis, finally cause asystole.
At present, mainly adopt dehydration to alleviate edema caused by the lung disorder clinically, use Western medicine Gu Er Soviet Union relief of symptoms always, use adrenocortical hormone, alleviate of the damage of some paathogenic factor lung according to situation to this kind disease.Use oxygen therapy and mechanichal respirator during the acute symptom performance, to keep the human body vital functions, so that try to gain time precious to one for treating disease.
Yet; Western medicine Gu Er Soviet Union costs an arm and a leg; Every price of Gu Er Soviet Union of market price 1.5ml:0.12g is about 3800 yuan, and every price of the Gu Er of 3ml:0.24g Soviet Union is about 6600 yuan, and the expense of great number has caused heavy financial burden to the patient; And the effect of Western medicine all is temporary alleviation, does not obtain the solution of essence for the basic state of an illness.Therefore, no matter be from therapeutic effect, economy, medication comfort level aspect, all press for a kind of instant effect, inexpensive, the medicine of respiratory distress syndrome is treated in medication easily.
The inventor through the conscientious research to Chinese crude drug, adopts the method for traditional medicine and modern science and technology combination based on field of Chinese herbal working experience for many years; Through experiment and exploration many times; The medicine that a kind of Chinese medicinal herbs of concentrating on studies out combines, this medicine have original therapeutic effect to the adult with the respiratory distress syndrome that neonate occurs from the function of the angular adjustment animal economy of tcm treatment according to syndrome differentiation; And can treat the acute and chronic respiratory failure that the human body respiration organ occurs; Clinical practice is extensive, and used medical material is all comparatively common, low price.Simultaneously, administering mode is various, can take orally, again can external treatment, solves the problem that exists in the prior art, for extensive patients brings glad tidings.
Summary of the invention
The purpose of this invention is to provide a kind of medicine of treatment respiratory distress syndrome, another purpose provides manufacturing method for above mentioned medicine.
Another purpose of the present invention provides the purposes of said medicine in treatment acute and chronic respiratory failure disease.
For achieving the above object, the present invention has adopted following technical scheme:
A kind of medicine of treating respiratory distress syndrome (ivrds), calculate according to components by weight percent: be to be processed by effective raw material of following weight proportion:
Folium Mori 10-30 part, Radix Rumicis 20-50 part, five-leaved chaste tree 20-50 part, Rhizoma Atractylodis 10-30 part, Herba Menthae 10-30 part, Radix Ophiopogonis 15-35 part, Radix Scutellariae 15-35 part.
Specifically, the medicine of said treatment respiratory distress syndrome (ivrds), calculate according to components by weight percent: be to be processed by effective raw material of following weight proportion:
10 parts on Folium Mori, 20 parts of Radix Rumiciss, 20 parts of five-leaved chaste trees, 10 parts of Rhizoma Atractylodis, 10 parts of Herba Menthaes, 15 parts of Radix Ophiopogonis, 15 parts of Radix Scutellariaes.
Medicine of the present invention, Folium Mori have dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, the effect of liver heat removing and eyesight improving, it is dim-sighted to be usually used in anemopyretic cold, lung-heat type cough, headache and dizzy, conjunctival congestion; Radix Rumicis ability heat-clearing and toxic substances removing, hemostasis, blood stasis dispelling, relieving constipation, parasite killing is used for lung abscess, hemoptysis of pulmonary tuberculosis; The five-leaved chaste tree function cures mainly and is relieving cough and asthma, and regulating QI to relieve pain is used for cough, asthma, stomachache; Rhizoma Atractylodis can be drying damp and strengthening spleen, dispels the wind, and cold expelling makes eye bright, and is usually used in rheumatic arthralgia, anemofrigid cold, nyctalopia nyctalopia etc.; The Herba Menthae dispelling wind-heat, the refresh oneself, rash is used for anemopyretic cold, pathogenic wind-warm from the beginning of, headache, conjunctival congestion, sore throat etc.; Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, lung moistening clears away heart-fire, and is used for dryness of the lung dry cough, chronic consumptive disease cough, disease such as Tianjin wound is thirsty; The Radix Scutellariae hot dampness that disappears, eliminating fire and detoxication, hemostasis is used for hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest.Above-mentioned each medicine is played the effect of removing heat-phlegm, depressed lung-energy dispersing, supplementing QI and nourishing YIN, Wen Tongxin kidney altogether; The function that the principle of utilization tcm treatment according to syndrome differentiation is regulated animal economy; Be very beneficial for alleviating and eliminate diseases such as dyspnea that respiratory distress syndrome (ivrds), acute and chronic respiratory failure cause, arrhythmia, nervous uncomfortable in chest, trick tidal surge of emotion heat, headache, tinnitus, treat respiratory distress syndrome (ivrds) and acute and chronic respiratory failure and have good effect.
The medicine of treatment respiratory distress syndrome (ivrds) of the present invention can be processed oral formulations such as oral liquid, tablet, capsule or granule.
Above-mentioned Chinese medicine preparation can be prepared from through following method:
Get Folium Mori, Radix Rumicis, five-leaved chaste tree, Rhizoma Atractylodis, Herba Menthae, Radix Ophiopogonis, radix scutellariae medicinal materials; Weighing is carried out by formula proportion in the screening back; After the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, immersion, remove by filter impurity; Fully mix, make Chinese medicine extract, add adjuvant according to conventional method then and be prepared into various required preparations.
Chinese medicine preparation of the present invention also can be prepared from through following method:
Get Folium Mori, Radix Rumicis, five-leaved chaste tree, Rhizoma Atractylodis, Herba Menthae, Radix Ophiopogonis, radix scutellariae medicinal materials, after screening, concoct, being ground into coarse powder, remove by filter impurity, take by weighing medicine, add 6-10 times of water gaging and decoct extraction 2-3 time by formula proportion; Each 1-3 hour, extracting solution merged, and filtered, and filtrating concentrates; To filtrate under agitation adds ethanol and makes the alcohol amount of containing be 50-70%, leaves standstill 12-24 hour, filters; Concentrate, the Chinese medicine extract of system is processed various required preparations according to conventional method then.
In addition; Principle according to Chinese medicine meridian health care treatment disease; Immersion in the Chinese crude drug extract adding Chinese liquor that makes among the preparation technology of the present invention was spread upon lobe of the lung cave, Baihui acupoint after 45 days, also can play certain treatment and preventive effect respiratory distress syndrome (ivrds) and acute and chronic respiratory failure.
Below the main clinical trial example of medicine of the present invention in treatment respiratory distress syndrome (ivrds), acute and chronic respiratory failure further set forth the beneficial effect of medicine according to the invention:
Test Example 1: the clinical efficacy of Drug therapy respiratory distress syndrome (ivrds) of the present invention, acute and chronic respiratory failure
Physical data
One, case choice criteria: tried case Standard Selection case in strict accordance with a kind of clinical drug checking plan of treating adult respiratory distress syndrome.
Two, diagnostic criteria: according to the tcm treatment according to syndrome differentiation principle, strict clinical drug by the treatment adult respiratory distress syndrome is verified the standard diagnostics of respiratory failure in the works.
Three, observation item: according to the specification requirement of clinical research in the Ministry of Public Health " provisions for new drugs approval ", observation item comprises safety and health giving quality two parts.
1, note observing: (1) hypoglycemia stimulation of carotid sinus and chemoreceptor of aortic body, reflexive stimulates respiratory center, produces hyperventilation; (2) pulmonary congestion, edema stimulate the other J induction apparatus of blood capillary, cause reflexive exaggerated respiration, quickening, cause respiratory distress.Early stage compensatory owing to what breathe, paco2 shows as normal or reduces.Severe patient because pulmonary ventilation volume reduces and respiratory distress increases the weight of respiratory muscle fatigue, can cause hypercapnia.
2, generally experience project: tongue picture and pulse condition observation.
3, laboratory examination: blood, urine, just routine test; Liver and kidney, cardiovascular and cerebrovascular vessel, kidney function test.
Four, Therapeutic Method
1, treatment group: the preparation of the embodiment of the invention 1-4 systems, according to the usage and dosage administration among the embodiment, 15 days is a course of treatment.
2, matched group: the Gu Er injection of reviving directly is instilled into administration by body weight along tracheal intubation, and dosage is: 100-200mg/kg, 2 times on the one, be a course of treatment January.
3, curative effect judging standard: according to the relevant Chinese medicine clinical research principle of developing and publishing in Ministry of Public Health (93) year, by the traditional Chinese medical science four diagnostic methods and pattern of syndrome integrated value, the decline situation is divided clinical cure, produce effects, is effectively reached invalidly, and level Four is judged.
Five, clinical data
The treatment group is totally 50 examples, male's 27 examples wherein, and women's 23 examples, at 1 years old-71 years old age, 37 years old mean age, course of disease June-50 year, majority is at 1-20, the arteries and veins card 18-32 branch of keeping the score, average 27.5 minutes.
Matched group is totally 50 examples, male's 25 examples wherein, and women's 25 examples, at 1-85 years old ages, average 57.5 years old, course of disease June-20 year, majority was in 1-10 year, the arteries and veins card 21-33 branch of keeping the score, average 26.4 minutes.
Six, observed result
The curative effect of 1, treatment group and matched group is seen table 1.
The curative effect comparison sheet of table 1 liang group experiment
| Group | The example number | Clinical recovery | Produce effects | Effectively | Invalid | Effective percentage % |
| The treatment group | 50 | 20 | 12 | 3 | 15 | 70 |
| Matched group | 50 | 18 | 8 | 4 | 20 | 60 |
The relation of 2, the treatment group curative effect and the course of disease is seen table 2.
The curative effect of table 2 preparation of the present invention and the relation of the course of disease
| The course of disease | The example number | Clinical recovery | Produce effects | Effectively | Invalid | Effective percentage % |
| < 10 years | 20 | 10 | 5 | 1 | 4 | 80 |
| 15 years | 10 | 2 | 3 | 1 | 4 | 60 |
| ≧ 20 years | 10 | 4 | 2 | 1 | 3 | 70 |
| ≧ 25 years | 10 | 4 | 2 | 0 | 4 | 60 |
Can know that by last table preparation of the present invention is better to the short patient's curative effect of the course of disease, but the disproportionate relation of the curative effect and the course of disease.
3, treatment group primary symptom curative effect is seen table 3.
The primary symptom curative effect of table 3 preparation of the present invention
4, safety is observed: during the medication, toxic and side effects and untoward reaction do not appear in the treatment group.
Seven, brief summary
With medicine of the present invention the human body respiration function is carried out clinical treatment; Treatment group effective percentage 70%; Matched group effective percentage 60%; Explain that medicine of the present invention has curative effect preferably in symptoms such as treatment acute respiratory failure, chronic respiratory failure, the poverty-stricken syndrome of infant's respiration, adult respiratory distress syndromes, treatment is organized 50 examples untoward reaction and toxic and side effects is taken place without exception.
Test Example 2: specific embodiment (clinical case)
1, Wang Xue carefree, women, 1 years old, medical history 0.3 year, the poverty-stricken syndrome of infant's respiration.Tcm diagnosis: the evil lung disease of pyretic toxicity.Symptom: breathe heavily the foot out of breath or opening mouth and lifting shoulder due to dyspnea, can not put down for sleeping in, the hyperpyrexia excessive thirst, face lip cyanosis, body of the tongue is deep red, white and thin fur or BOHUANG, full and rapid pulse.Western medicine diagnose: respiratory failure, attained female medium-height grass institute of Pharmaceutical Research Affiliated Hospital in 2002 in Guizhou Province and go to a doctor, utilize the method for heat-clearing and toxic substances removing, ventilating lung qi for lowering adverse qi, take medicine of the present invention after one course of treatment, above-mentioned symptom obviously alleviates, and continues to take two courses of treatment, transference cure.
2, Feng Jingjing, woman, 6 years old, medical history are 3 years, respiratory distress syndrome.Tcm diagnosis: phlegm-heat obstructing in the lung disease.The patient arrived zunyi, guizhou province new bridge hospital admission in 2002; The head of a family has reported 3 years of morbidity, and morbidity is in the past sent in hospital exactly, and hospital all is the doctor trained in Western medicine that adopts; Infuse, have an injection; Also used Gu Er Soviet Union, but all be temporary being eased at every turn, it is desirable to that individual good curing can be arranged but come specifically for the solution that the basic state of an illness does not obtain essence.Only see its symptom: breathe heavily sufficient gas and gush, cough with copious phlegm, sticky yellow skin, or sputum mixed with blood, companion's irritable feverish sensation in the chest, dry throat and mouth, dark coloured urine constipation, red tongue, yellow and greasy fur, slippery and rapid pulse.Utilize medicine of the present invention after one course of treatment in this institute, above-mentioned symptom obviously alleviates and feels spirit and QI cleaning, breathes smooth and easyly, continues to take three courses of treatment, above-mentioned symptom and disappears basically.
3, Yang Xianxiu, woman, 65 years old, medical history 15 years, chronic respiratory failure, tcm diagnosis: syndrome of qi deficiency of lung and kidney; Symptom: it is continuous to breathe narrow and shallow difficulty, opening mouth and lifting shoulder due to dyspnea very then, can not put down for sleeping in, fullness in the chest and shortness of breath; Cardiopalmus, cough, expectorant Bai Rumo, difficulty in expectorating; Coldness of the body and sweating, light red tongue or dim purple, white and moist fur, deep,thready and forceless pulse or the knot generation.Patient's readme was come in sick 15 years, used western medicine and medical practitioners always, transfusion; Have an injection, but effect wherein is little, attain the treatment of female medium-height grass institute of Pharmaceutical Research Affiliated Hospital and take medicine of the present invention after 2 courses of treatment in Guizhou Province that comes in JIUYUE, 2003; Above symptom alleviates to some extent, takes the preparation of 5 courses of treatment subsequently again, and symptom disappears basically; Freedom of movement, not recurrence as yet so far.
4, Marvin's open, man, 65 years old, Xiuwen County, Guiyang retired worker.Tcm diagnosis: syndrome of yang deficiency of heart and kidney, symptom: it is rapid to breathe, and opening mouth and lifting shoulder due to dyspnea is exhaled and is inhaled fewly, moving then breathe heavily very more, and Mental fatigue is breathed hard, cold extremities due to sweating, cyanosis of the face and lips, pale tongue, deep,thready and forceless pulse, Western medicine diagnose: adult respiratory distress syndrome.The patient seeks medical advice in new bridge hospital in zunyi, guizhou province over 2003, and example slightly in spite of illness, tells about and suffers from this card several years, various in, Western medicine eaten much; Be exactly not slow to separate, this institute utilizes the principle of tcm treatment according to syndrome differentiation according to its state of an illness, adopts medicine of the present invention to take by it; The patient writes letters reaction after the course of treatment, and above-mentioned symptom alleviates, posted the drug administration of 5 courses of treatment subsequently after; Transference cure is breathed and is recovered as before, so far not recurrence.Medicine of the present invention has the effect of removing heat-phlegm, depressed lung-energy dispersing, supplementing QI and nourishing YIN, Wen Tongxin kidney through above-mentioned evidence, and respiratory distress syndrome (ivrds), acute and chronic respiratory failure are had good efficacy.Effect is remarkable, and has no side effect, for the medication of respiratory distress syndrome (ivrds), acute and chronic respiratory failure provides another excellent choosing.The specific embodiment
Do bright specifically below in conjunction with implementing to the present invention.
Embodiment 1:
Folium Mori 10 restrain, Radix Rumicis 20 restrains, five-leaved chaste tree 20 restrains, Rhizoma Atractylodis 10 restrain, Herba Menthae 10 restrains, restrain Radix Ophiopogonis 15, Radix Scutellariae 15 restrains.
Method for preparing: get Folium Mori, Radix Rumicis, five-leaved chaste tree, Rhizoma Atractylodis, Herba Menthae, Radix Ophiopogonis, radix scutellariae medicinal materials, weighing is carried out by formula proportion in the screening back, after the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, immersion, removes by filter impurity, fully mixes; Make Chinese medicine extract, add starch 1:1 then and mix, crushed after being dried becomes fine powder, sieves; Ethanol with 85% is wetting agent, system granule, 60-70 ℃ of drying; Add 2% Pulvis Talci uniform mixing, be pressed into tablet, the 0.3g/ sheet.
Usage and consumption: oral, three times on the one, each 2-4 sheet.
Embodiment 2:
Folium Mori 30 restrain, Radix Rumicis 50 restrains, five-leaved chaste tree 50 restrains, Rhizoma Atractylodis 30 restrain, Herba Menthae 30 restrains, restrain Radix Ophiopogonis 35, Radix Scutellariae 35 restrains.
Method for preparing: get Folium Mori, Radix Rumicis, five-leaved chaste tree, Rhizoma Atractylodis, Herba Menthae, Radix Ophiopogonis, radix scutellariae medicinal materials; Weighing is carried out by formula proportion in the screening back; After the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, immersion, remove by filter impurity, fully mix, make Chinese medicine extract; Add a certain amount of starch and microcrystalline Cellulose then, process capsule.0.3g/ grain.
Usage and consumption: oral, three times on the one, each 2-4 grain.
Embodiment 3:
Folium Mori 15 restrain, Radix Rumicis 30 restrains, five-leaved chaste tree 30 restrains, Rhizoma Atractylodis 15 restrain, Herba Menthae 15 restrains, restrain Radix Ophiopogonis 23, Radix Scutellariae 23 restrains.
Method for preparing: get Folium Mori, Radix Rumicis, five-leaved chaste tree, Rhizoma Atractylodis, Herba Menthae, Radix Ophiopogonis, radix scutellariae medicinal materials, after screening, concoct, being ground into coarse powder, remove by filter impurity, take by weighing medicine by formula proportion; Add 6 times of water gagings and decoct extraction 2 times, each 1 hour, extracting solution merged; Filter, filtrating concentrates, and will filtrate under agitation to add ethanol and make that to contain that alcohol measures be 50%; Left standstill 12 hours, and filtered, concentrate; Concentrate the ratio uniform mixing of back in extract and starch, cane sugar powder 1:1:2.5,60-70 ℃ of drying, granule is processed in packing.The 10g/ bag.
Usage and consumption: boiled water is taken after mixing it with water, and three times on the one, each 10-20g.
Embodiment 4:
Folium Mori 20 restrain, Radix Rumicis 40 restrains, five-leaved chaste tree 40 restrains, Rhizoma Atractylodis 20 restrain, Herba Menthae 20 restrains, restrain Radix Ophiopogonis 30, Radix Scutellariae 30 restrains.
Method for preparing:
Get Folium Mori, Radix Rumicis, five-leaved chaste tree, Rhizoma Atractylodis, Herba Menthae, Radix Ophiopogonis, radix scutellariae medicinal materials, after screening, concoct, being ground into coarse powder, remove by filter impurity, take by weighing medicine, add 10 times of water gagings and decoct extraction 3 times by formula proportion; Each 3 hours, extracting solution merged, and filtered, and filtrating concentrates; To filtrate under agitation adds ethanol and makes that to contain alcohol amount be 70%, leaves standstill 24 hours, filters, and concentrates; Concentrate the back simple syrup and add to sugar content 10%, add 0.2 fen sodium benzoate, boil dissolving, adding distil water is to full dose; Mixing filters, and oral liquid is processed in embedding.10ml/ props up.
Usage and consumption: oral, three times on the one, each 10ml.
Claims (8)
1. medicine of treating respiratory distress syndrome is characterized in that: be to be processed by effective raw material of following weight proportion:
Folium Mori 10-30 part, Radix Rumicis 20-50 part, five-leaved chaste tree 20-50 part, Rhizoma Atractylodis 10-30 part, Herba Menthae 10-30 part, Radix Ophiopogonis 15-35 part, Radix Scutellariae 15-35 part.
2. a kind of medicine of treating respiratory distress syndrome (ivrds) according to claim 1 is characterized in that: be to be processed by effective raw material of following weight proportion:
10 parts on Folium Mori, 20 parts of Radix Rumiciss, 20 parts of five-leaved chaste trees, 10 parts of Rhizoma Atractylodis, 10 parts of Herba Menthaes, 15 parts of Radix Ophiopogonis, 15 parts of Radix Scutellariaes.
3. according to the arbitrary described a kind of medicine of treating respiratory distress syndrome (ivrds) of claim 1-2, it is characterized in that: the medicine of described treatment respiratory distress syndrome (ivrds) is processed oral liquid, tablet, capsule or granule.
4. according to the arbitrary described a kind of medicine of treating respiratory distress syndrome (ivrds) of claim 1-2, it is characterized in that:
Method for preparing is: get Folium Mori, Radix Rumicis, five-leaved chaste tree, Rhizoma Atractylodis, Herba Menthae, Radix Ophiopogonis, radix scutellariae medicinal materials; Weighing is carried out by formula proportion in the screening back; After the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, immersion, remove by filter impurity; Fully mix, make Chinese medicine extract, add adjuvant according to conventional method then and be prepared into various required preparations.
5. according to the arbitrary described a kind of medicine of treating respiratory distress syndrome (ivrds) of claim 1-2, it is characterized in that: method for preparing is: get Folium Mori, Radix Rumicis, five-leaved chaste tree, Rhizoma Atractylodis, Herba Menthae, Radix Ophiopogonis, radix scutellariae medicinal materials, after screening, concoct, being ground into coarse powder, remove by filter impurity; Take by weighing medicine by formula proportion, add 6-10 times of water gaging and decoct extraction 2-3 time, each 1-3 hour; Extracting solution merges, and filters, and filtrating concentrates; To filtrate under agitation adds ethanol and makes the alcohol amount of containing be 50-70%, leaves standstill 12-24 hour, filters; Concentrate, the Chinese medicine extract of system is processed various required preparations according to conventional method then.
6. a kind of medicine of treating respiratory distress syndrome (ivrds) according to claim 4 is characterized in that:
Method for preparing is: get Folium Mori, Radix Rumicis, five-leaved chaste tree, Rhizoma Atractylodis, Herba Menthae, Radix Ophiopogonis, radix scutellariae medicinal materials; Weighing is carried out by formula proportion in the screening back; After the process of preparing Chinese medicine, steaming and decocting, oven dry, pulverizing, filtration, cream refining, immersion, remove by filter impurity; Fully mix, make Chinese medicine extract, add in the Chinese liquor and soaked 45 days.
7. a kind of drug use method of treating respiratory distress syndrome (ivrds) according to claim 6 is characterized in that: this medicine is spread upon on lobe of the lung cave, the Baihui acupoint.
8. according to the arbitrary described a kind of purposes of medicine in treatment acute and chronic respiratory failure disease of treating respiratory distress syndrome (ivrds) of claim 1-2.
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| CN104906439A (en) * | 2015-07-03 | 2015-09-16 | 李慧 | Medicine for treating chronic respiratory failure |
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| JP2007084459A (en) * | 2005-09-20 | 2007-04-05 | Hirotaro Kurosaka | Composition for treating fibrotic disease |
| CN102048970A (en) * | 2009-10-31 | 2011-05-11 | 凌志荣 | Pharmaceutical composition for treating cough |
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Application publication date: 20121114 |
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