CN102772578B - Traditional Chinese composition for treating beriberi - Google Patents
Traditional Chinese composition for treating beriberi Download PDFInfo
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Abstract
The invention discloses a traditional Chinese composition for treating beriberi, which is prepared from the following bulk drugs in parts by weight: 20-40 parts of tea oil, 3-6 parts of coptis chinensis, 5-15 parts of flowers of Chinese scholartree, 5-15 parts of whorlleaf stonecrop herb, 3-8 parts of mint powder, 5-15 parts of alum powder, 3-8 parts of charcoal dust, 3-8 parts of sulfa powder, 5-15 parts of phoenix tree flowers, and 6-12 parts of vaseline. The traditional Chinese composition has easily obtained raw materials, low cost and simple preparation method, has the efficacies of clearing away heat and dampness, detoxifying and relieving itching, stopping bleeding and diminishing swelling, and removing slough and promoting tissue regeneration, and has a good curative effect on beriberi and complications thereof.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition that is used for the treatment of beriberi, belong to the field of Chinese medicines.
Background technology
Beriberi, also be tinea pedis, is a kind of common fungal infection dermatoses, is divided into clinically vesicle beriberi, erosive beriberi and keratinization type beriberi.This disease sickness rate is high, infectiousness strong, difficulty is effected a radical cure, easily recurrence, brings great puzzlement usually for patient's life and work.As can not get treating timely, other position to other people or self be can infect, as the tinea manuum and tinea unguium etc. caused, pedal skin is scratched because of the pain of itching sometimes, also can infect by the secondary antibacterial, causes serious complication.
The conventional medicine for the treatment of beriberi is mainly that some energy are antibacterial, sterilizing, the ointment machin liquid of antiinflammatory at present, take external as main, but generally in treatment, easily recurs afterwards, is difficult to radical cure, and skin is had to certain infringement.
Chinese patent literature CN101810720A discloses a kind of skin disease external powder of comprehensively killing inhibiting bacteria and diminishing inflammation and the using method on beriberi skin disease thereof, its crude drug comprises Cortex Phellodendri, Borneolum Syntheticum, Mentholum, Alumen, Pulvis Talci, sulfamethoxazole, metronidazole, griseofulvin, chloromycetin, aspirin, chlorphenamine, vitamin B1, has virus killing, sterilization, antibacterial, antiinflammatory, antipruritic, analgesia, heat-clearing and toxic substances removing, convergence sweat gland, goes the effect of antiperspirant, deodorization.But this medicated powder comprises the antibiotic such as griseofulvin, chloromycetin, easily cause the generation of " super bacterium ", separately contain the number of chemical medicines such as sulfamethoxazole, metronidazole, aspirin, chlorphenamine, zest to skin is large, easily cause the damage of skin, and after curing, easily recurrence, poor to vesicle beriberi and erosive beriberi therapeutic effect.
Summary of the invention
Technical problem to be solved by this invention is that the medicine that is used for the treatment of beriberi in prior art contains antibiotic, skin is had to stimulation, to vesicle beriberi and the poor problem of erosive beriberi therapeutic effect, provide a kind of and do not contain antibiotic, non-stimulated and erosive type and vesicle vitamin B1 deficiency are had to Chinese medicine composition and a preparation method of good efficacy to skin.
The invention provides a kind of Chinese medicine composition, the weight portion of said composition crude drug is: Oleum Camelliae 20-40 part, Rhizoma Coptidis 3-6 part, Flos Sophorae 5-15 part, Herba Hylothelephii Verticillati 5-15 part, Herba Menthae powder 3-8 part, alum powder 5-15 part, charcoal powder 3-8 part, sulfa powder 3-8 part, Flos Firmianae (Flow Flos firmianae) 5-15 part, vaseline 6-12 part.
The weight portion of preferred crude drug of the present invention is: Oleum Camelliae 25-35 part, Rhizoma Coptidis 3-6 part, Flos Sophorae 8-12 part, Herba Hylothelephii Verticillati 8-12 part, Herba Menthae powder 4-6 part, alum powder 8-12 part, charcoal powder 4-6 part, sulfa powder 4-6 part, Flos Firmianae (Flow Flos firmianae) 8-12 part, vaseline 7-9 part.
The weight portion of best crude drug of the present invention is: 30 parts of Oleum Camelliae, 8 parts of Rhizoma Coptidis, 10 parts, Flos Sophorae, 10 parts of Herba Hylothelephii Verticillatis, 5 parts of Herba Menthae powders, 10 parts of alum powders, 10 parts of charcoal powders, 5 parts of sulfa powders, 10 parts of Flos Firmianae (Flow Flos firmianae), 8 parts, vaseline.
Described Chinese medicine composition is made into any external-use drug form.
Described Chinese medicine composition is made into unguentum, patch or liquor.
The preparation method of described Chinese medicine composition, comprise the steps:
A) get Flos Sophorae, Flos Firmianae (Flow Flos firmianae), Herba Hylothelephii Verticillati respectively cleaning, drying be crushed to fine powder;
B) Oleum Camelliae is heated to 80-100 ℃, adds respectively Flos Sophorae powder, platanus hispanica pollen, explode ripe and stir;
C) above-mentioned Oleum Camelliae liquid is cooled to 20-30 ℃, adds respectively sulfa powder, the grass meal of reviving after death, alum powder, charcoal powder, Rhizoma Coptidis powder, after this add Herba Menthae powder, stir;
D) by the vaseline heating for dissolving, add above-mentioned medicinal liquid, stir and get final product.
In described step a), fine powder is 120 orders.
The invention still further relates to the purposes of described Chinese medicine composition in preparation treatment beriberi.
Theory of Chinese medical science thinks that beriberi is because of the affection of exogenous damp pathogenic wind toxic, or the diet savoury hinders, long-pending humidogene heat, and multiple abscess legs and feet and causing a disease, so the principle of Chinese traditional treatment beriberi is mainly heat clearing and damp drying, detoxify, and parasite killing is antipruritic.
Oleum Camelliae is cool in nature, and sweet in the mouth is returned large intestine channel, the effect of tool heat-clearing and toxic substances removing, parasite killing, Rhizoma Coptidis is cold in nature, bitter in the mouth, GUIXIN, spleen, stomach, liver, gallbladder, large intestine channel, tool heat clearing and damp drying, the effect of eliminating fire and detoxication, alum powder is cold in nature, sour in the mouth, puckery, tool detoxifcation parasite killing, dampness removing to stop itchin, the effect of hemostasis heat clearing away, three's phase 5, play heat clearing and damp drying, detoxifcation, parasite killing, itching-relieving efficacies, be monarch drug altogether.
The significant antiinflammatory of sulfa powder tool, antibacterial effect, Flos Sophorae is cool in nature, and bitter in the mouth is returned liver, large intestine channel, the effect of tool clearing away heat-fire, cooling blood for hemostasis, both phases 5, strengthen heat clearing away, parasite killing, antipruritic effect, be ministerial drug altogether.
Herba Menthae powder is cool in nature, and acrid in the mouth is returned lung, Liver Channel, the effect of tool detumescence antiinflammatory, analgesic hemostatic, Herba Hylothelephii Verticillati is flat, bitter in the mouth, the effect of tool detoxifcation, detumescence, hemostasis, the effect of charcoal powder Bearberry Extract hemostasis, Flos Firmianae (Flow Flos firmianae) is flat, sweet in the mouth, the effect of tool reducing swelling and alleviating pain, this mutually 5, play the effect of astringing to arrest bleeding, putrefaction-removing granulation-promoting, detumescence, in order to treat blister that vitamin B1 deficiency causes, to fester, be adjuvant drug altogether.
Vaseline, as excipient, also has the effect of skin protection, skin moistening, antiinflammatory and deodorization simultaneously.
Above ten flavor medicine fit applications, the effect of playing altogether heat clearing and damp drying, detoxifying and relieving itching, hemostasia and detumescence, analgesic antiphlogistic, putrefaction-removing granulation-promoting, all have good efficacy to vitamin B1 deficiency and complication thereof.
The present invention has following advantage:
The present invention selects Oleum Camelliae, Rhizoma Coptidis, Flos Sophorae, Herba Hylothelephii Verticillati, Herba Menthae powder, alum powder, charcoal powder, sulfa powder, Flos Firmianae (Flow Flos firmianae), vaseline are raw material, and the effect of playing altogether heat clearing and damp drying, detoxifying and relieving itching, hemostasia and detumescence, analgesic antiphlogistic, putrefaction-removing granulation-promoting all has good efficacy to vitamin B1 deficiency and complication thereof.Because crude drug does not contain antibiotic, avoided the generation of " super bacterium ", except sulfa powder, the present invention does not contain other chemicals composition, the damage of having avoided a large amount of chemicalses to cause skin, because Herba Menthae powder, Herba Hylothelephii Verticillati, charcoal powder, Flos Firmianae (Flow Flos firmianae) in crude drug of the present invention have the effect of astringing to arrest bleeding, putrefaction-removing granulation-promoting, detumescence, therefore good to vesicle beriberi and erosive beriberi therapeutic effect in addition.
The specific embodiment
Embodiment 1
Take Oleum Camelliae 20g, Rhizoma Coptidis 3g, Flos Sophorae 5g, Herba Selaginellae 5g, Herba Menthae powder 3g, alum powder 5g, charcoal powder 3g, sulfa powder 3g, Flos Firmianae (Flow Flos firmianae) 5g, vaseline 6g;
By Flos Sophorae, Flos Firmianae (Flow Flos firmianae), Herba Selaginellae respectively cleaning, drying be crushed to 80 order fine powders; Oleum Camelliae is heated to 80-100 ℃, adds respectively Flos Sophorae powder, platanus hispanica pollen, explode ripe and stir; Above-mentioned Oleum Camelliae liquid is cooled to 20-30 ℃, adds sulfa powder, Herba Selaginellae powder, alum powder, charcoal powder, Rhizoma Coptidis powder, after this add Herba Menthae powder, stir; By the vaseline heating for dissolving, add above-mentioned medicinal liquid, stir and get final product.
Embodiment 2
Take Oleum Camelliae 30g, Rhizoma Coptidis 4.5g, Flos Sophorae 10g, Herba Selaginellae 10g, Herba Menthae powder 5g, alum powder 10g, charcoal powder 5g, sulfa powder 5g, Flos Firmianae (Flow Flos firmianae) 10g, vaseline 9g;
By Flos Sophorae, Flos Firmianae (Flow Flos firmianae), Herba Selaginellae respectively cleaning, drying be crushed to 160 order fine powders; Oleum Camelliae is heated to 80-100 ℃, adds respectively Flos Sophorae powder, platanus hispanica pollen, explode to pitchy and stir; Above-mentioned Oleum Camelliae liquid is cooled to 20-30 ℃, adds sulfa powder, Herba Selaginellae powder, alum powder, charcoal powder, Rhizoma Coptidis powder, after this add Herba Menthae powder, stir into the pitchy medicinal liquid; By the vaseline heating for dissolving, add above-mentioned medicinal liquid, stir and get final product.
Embodiment 3
Take Oleum Camelliae 40g, Rhizoma Coptidis 6g, Flos Sophorae 15g, Herba Selaginellae 15g, Herba Menthae powder 8g, alum powder 15g, charcoal powder 8g, sulfa powder 8g, Flos Firmianae (Flow Flos firmianae) 15g, vaseline 12g;
By Flos Sophorae, Flos Firmianae (Flow Flos firmianae), Herba Selaginellae respectively cleaning, drying be crushed to 120 order fine powders; Oleum Camelliae is heated to 80-100 ℃, adds respectively Flos Sophorae powder, platanus hispanica pollen, explode to pitchy and stir; Above-mentioned Oleum Camelliae liquid is cooled to 20-30 ℃, adds sulfa powder, Herba Selaginellae powder, alum powder, charcoal powder, Rhizoma Coptidis powder, after this add Herba Menthae powder, stir into the pitchy medicinal liquid; By the vaseline heating for dissolving, add above-mentioned medicinal liquid, stir into the pitchy ointment.
Embodiment 4
Take Oleum Camelliae 25g, Rhizoma Coptidis 3g, Flos Sophorae 8g, Herba Selaginellae 8g, Herba Menthae powder 4g, alum powder 8g, charcoal powder 4g, sulfa powder 4g, Flos Firmianae (Flow Flos firmianae) 8g, vaseline 7g;
By Flos Sophorae, Flos Firmianae (Flow Flos firmianae), Herba Selaginellae respectively cleaning, drying be crushed to 120 order fine powders; Oleum Camelliae is heated to 80-100 ℃, adds respectively Flos Sophorae powder, platanus hispanica pollen, explode to pitchy and stir; Above-mentioned Oleum Camelliae liquid is cooled to 20-30 ℃, adds sulfa powder, Herba Selaginellae powder, alum powder, charcoal powder, Rhizoma Coptidis powder, after this add Herba Menthae powder, stir into the pitchy medicinal liquid; By the vaseline heating for dissolving, add above-mentioned medicinal liquid, stir into the pitchy ointment.
Embodiment 5
Take Oleum Camelliae 30g, Rhizoma Coptidis 4.5g, Flos Sophorae 10g, Herba Selaginellae 10g, Herba Menthae powder 5g, alum powder 10g, charcoal powder 5g, sulfa powder 5g, Flos Firmianae (Flow Flos firmianae) 10g, vaseline 8g;
By Flos Sophorae, Flos Firmianae (Flow Flos firmianae), Herba Selaginellae respectively cleaning, drying be crushed to 100 order fine powders; Oleum Camelliae is heated to 80-100 ℃, adds respectively Flos Sophorae powder, platanus hispanica pollen, explode to pitchy and stir; Above-mentioned Oleum Camelliae liquid is cooled to 20-30 ℃, adds sulfa powder, Herba Selaginellae powder, alum powder, charcoal powder, Rhizoma Coptidis powder, after this add Herba Menthae powder, stir into the pitchy medicinal liquid; By the vaseline heating for dissolving, add above-mentioned medicinal liquid, stir and get final product.
Embodiment 6
Take Oleum Camelliae 35g, Rhizoma Coptidis 6g, Flos Sophorae 12g, Herba Selaginellae 12g, Herba Menthae powder 6g, alum powder 12g, charcoal powder 6g, sulfa powder 6g, Flos Firmianae (Flow Flos firmianae) 12g, vaseline 9g;
By Flos Sophorae, Flos Firmianae (Flow Flos firmianae), Herba Selaginellae respectively cleaning, drying be crushed to 120 order fine powders; Oleum Camelliae is heated to 80-100 ℃, adds respectively Flos Sophorae powder, platanus hispanica pollen, explode to pitchy and stir; Above-mentioned Oleum Camelliae liquid is cooled to 20-30 ℃, adds sulfa powder, Herba Selaginellae powder, alum powder, charcoal powder, Rhizoma Coptidis powder, after this add Herba Menthae powder, stir into the pitchy medicinal liquid; By the vaseline heating for dissolving, add above-mentioned medicinal liquid, stir into the pitchy ointment.
Embodiment 7
Take Oleum Camelliae 30g, Rhizoma Coptidis 8g, Flos Sophorae 10g, Herba Selaginellae 10g, Herba Menthae powder 5g, alum powder 10g, charcoal powder 10g, sulfa powder 5g, Flos Firmianae (Flow Flos firmianae) 10g, vaseline 8g;
By Flos Sophorae, Flos Firmianae (Flow Flos firmianae), Herba Selaginellae respectively cleaning, drying be crushed to 120 order fine powders; Oleum Camelliae is heated to 80-100 ℃, adds respectively Flos Sophorae powder, platanus hispanica pollen, explode to pitchy and stir; Above-mentioned Oleum Camelliae liquid is cooled to 20-30 ℃, adds sulfa powder, Herba Selaginellae powder, alum powder, charcoal powder, Rhizoma Coptidis powder, after this add Herba Menthae powder, stir into the pitchy medicinal liquid; By the vaseline heating for dissolving, add above-mentioned medicinal liquid, stir into the pitchy ointment.
Embodiment 8
Take Oleum Camelliae 30g, Rhizoma Coptidis 8g, Flos Sophorae 10g, Herba Selaginellae 10g, Herba Menthae powder 5g, alum powder 10g, charcoal powder 10g, sulfa powder 5g, Flos Firmianae (Flow Flos firmianae) 10g, vaseline 8g;
By Flos Sophorae, Flos Firmianae (Flow Flos firmianae), Herba Selaginellae respectively cleaning, drying be crushed to 120 order fine powders; Oleum Camelliae is heated to 80-100 ℃, adds respectively Flos Sophorae powder, platanus hispanica pollen, explode to pitchy and stir; Above-mentioned Oleum Camelliae liquid is cooled to 20-30 ℃, adds sulfa powder, Herba Selaginellae powder, alum powder, charcoal powder, Rhizoma Coptidis powder, after this add Herba Menthae powder, stir into the pitchy medicinal liquid; By the vaseline heating for dissolving, add above-mentioned medicinal liquid, stir into the pitchy ointment, evenly, on coating and cotton, prepare patch.
Experimental example
In order to show the therapeutic effect of this Chinese medicine composition to beriberi, the present invention is through 100 routine system clinical observations, vesicle beriberi patient 30 examples wherein, erosive beriberi patient 30 example and keratinization type beriberi patient 40 examples.In the process of above-mentioned clinical observation, and the work of above-mentioned patient being recorded to its medical history, the state of an illness, age and curative effect.
The criterion of clinical therapeutic efficacy is:
Clinical cure: foot odor, foot pruritus, desquamation, blister, abscess, red moistening disappearance fully, it is normal that sweaty foot recovers.
Produce effects: foot odor, foot pruritus, sweaty foot, desquamation, blister, abscess, red moisteningly obviously alleviate.
Effectively: foot odor, foot pruritus, sweaty foot alleviate.
Invalid: foot odor, foot pruritus, sweaty foot disappear not obvious or increase the weight of.
Medication is: smear the unguentum of embodiment 7 preparations for patient's affected part.
The course for the treatment of: 15 days is a course for the treatment of, uses every day twice.
The clinical experiment result shows, only uses this Chinese medicine composition of a course for the treatment of, and original symptom obviously alleviates.According to statistics, the lighter patient of 5% symptom, can once cure, and after using a course for the treatment of, reaches 95% cure rate, and 5% produce effects or improvement, without invalid situation (in Table 1).
Contrast experiment's example
Take Cortex Phellodendri 5g, Borneolum Syntheticum 4g, Mentholum 5g, Alumen 2.5g, Pulvis Talci 55g, sulfamethoxazole 2.5g, metronidazole 10g, griseofulvin 4.5g, chloromycetin 2.5g, aspirin 2.5g, chlorphenamine 1.5g, vitamin B
11.5g nanometer silver powder 0.5g, make medicated powder according to the disclosed method of aforementioned Chinese patent literature CN101810720A.Use this product to carry out clinic trial to 100 routine patients of identical body constitution, state of an illness state, medication is a 33g, 2 times on the one, and the diet irritable food.According to the disclosed method administration of aforementioned Chinese patent literature CN101810720A application examples 1.
After successive administration 15 days, result is as shown in table 2, and its average cure rate reaches 65%, and has the some patients were affected part to produce " super bacterium ", and the red swelling of the skin phenomenon is wherein especially poor to vesicle beriberi and erosive beriberi therapeutic effect.
Although the present invention elaborates it by above-mentioned specific embodiment; but; those skilled in the art should be understood that any form that does not exceed the claim protection domain made on this basis and the variation of details, all belong to invention which is intended to be protected.
Claims (9)
1. Chinese medicine composition that is used for the treatment of beriberi, it is characterized in that, the weight portion of said composition crude drug is: Oleum Camelliae 20-40 part, Rhizoma Coptidis 3-6 part, Flos Sophorae 5-15 part, Herba Hylothelephii Verticillati 5-15 part, Herba Menthae powder 3-8 part, alum powder 5-15 part, charcoal powder 3-8 part, sulfa powder 3-8 part, Flos Firmianae (Flow Flos firmianae) 5-15 part, vaseline 6-12 part.
2. be used for the treatment of according to claim 1 the Chinese medicine composition of beriberi, it is characterized in that, the weight portion of described crude drug is: Oleum Camelliae 25-35 part, Rhizoma Coptidis 3-6 part, Flos Sophorae 8-12 part, Herba Hylothelephii Verticillati 8-12 part, Herba Menthae powder 4-6 part, alum powder 8-12 part, charcoal powder 4-6 part, sulfa powder 4-6 part, Flos Firmianae (Flow Flos firmianae) 8-12 part, vaseline 7-9 part.
3. the described Chinese medicine composition that is used for the treatment of beriberi according to claim 1 and 2, is characterized in that, described Chinese medicine composition is made into any external-use drug form.
4. be used for the treatment of according to claim 3 the Chinese medicine composition of beriberi, it is characterized in that, described Chinese medicine composition is made into unguentum or patch.
5. a Chinese medicine composition that is used for the treatment of beriberi, is characterized in that, the weight portion of described crude drug is: 30 parts of Oleum Camelliae, 8 parts of Rhizoma Coptidis, 10 parts, Flos Sophorae, 10 parts of Herba Hylothelephii Verticillatis, 5 parts of Herba Menthae powders, 10 parts of alum powders, 10 parts of charcoal powders, 5 parts of sulfa powders, 10 parts of Flos Firmianae (Flow Flos firmianae), 8 parts, vaseline.
6. be used for the treatment of according to claim 5 the Chinese medicine composition of beriberi, it is characterized in that, described Chinese medicine composition is made into any external-use drug form.
7. be used for the treatment of according to claim 6 the Chinese medicine composition of beriberi, it is characterized in that, described Chinese medicine composition is made into unguentum or patch.
8. the preparation method of claim 4 or 7 described Chinese medicine compositions, comprise the steps:
A) get Flos Sophorae, Flos Firmianae (Flow Flos firmianae), Herba Hylothelephii Verticillati respectively cleaning, drying be crushed to fine powder;
B) Oleum Camelliae is heated to 80-100 ℃, adds respectively Flos Sophorae powder, platanus hispanica pollen, explode ripe and stir;
C) above-mentioned Oleum Camelliae liquid is cooled to 20-30 ℃, adds respectively sulfa powder, the grass meal of reviving after death, alum powder, charcoal powder, Rhizoma Coptidis powder, after this add Herba Menthae powder, stir;
D) by the vaseline heating for dissolving, add above-mentioned medicinal liquid, stir and get final product.
9. the preparation method of Chinese medicine composition according to claim 8, is characterized in that, in described step a), fine powder is 120 orders.
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| CN104274730A (en) * | 2014-10-21 | 2015-01-14 | 浙江工贸职业技术学院 | Pharmaceutical composition for treating barbiers and preparation method of pharmaceutical composition |
| CN105770204A (en) * | 2016-05-27 | 2016-07-20 | 孙明香 | Traditional Chinese medicine ointment for treating blister type dermatophytosis and preparing method thereof |
| CN106063809A (en) * | 2016-06-18 | 2016-11-02 | 楚雄医药高等专科学校 | A kind of pharmaceutical composition and preparation method thereof, preparation and application |
| CN105998381A (en) * | 2016-07-04 | 2016-10-12 | 李灵芝 | Beriberi powder drug and preparation method thereof |
| CN107519470A (en) * | 2017-09-26 | 2017-12-29 | 黄经卫 | A kind of Chinese medicine composition for treating tinea pedis |
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Effective date of registration: 20160425 Address after: Luohe City, Henan province 462331 Yuanhui District Riverside Metro Xiangjiang Road Patentee after: Henan Shuguang qualied Kang biological Polytron Technologies Inc Address before: Luohe City, Henan province 462331 Yuanhui District Riverside Metro Xiangjiang Road Patentee before: Henan Shugang Jianshi Medical Devices Group Co., Ltd. |