CN102772561B - One is used for the treatment of psoriasic Chinese medicine - Google Patents

One is used for the treatment of psoriasic Chinese medicine Download PDF

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CN102772561B
CN102772561B CN201210243899.0A CN201210243899A CN102772561B CN 102772561 B CN102772561 B CN 102772561B CN 201210243899 A CN201210243899 A CN 201210243899A CN 102772561 B CN102772561 B CN 102772561B
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psoriasis
treatment
radix
chinese medicine
psoriasic
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CN102772561A (en
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顾康春
顾华盾
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Abstract

What the present invention proposed is that one is used for the treatment of psoriasic Chinese medicine.Be made up of Herba Taraxaci, Radix Scrophulariae, Rhizoma Zingiberis Recens silkworm, Zaocys, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Sophorae Flavescentis, Cortex Dictamni, each 5 ~ 30 grams of Radix Glycyrrhizae.Oral.By the oral treatment by Chinese herbs test of the present invention of 41 routine psoriatic, through statistics, cure rate accounts for 75.6%, alleviates and alleviates rate and account for 14.6%.Suitable to the psoriasic oral Chinese medicine application for the treatment of.

Description

One is used for the treatment of psoriasic Chinese medicine
Technical field
What the present invention proposed is that field of medicaments one is used for the treatment of psoriasic Chinese medicine.
Background technology
Psoriasis: be a kind of common chronic dermatosis, it is characterized in that in erythema, repeatedly occur the dry squama of multilamellar silvery white, peelling off squama has obvious petechia.It is characterized in that the pimple occurring differing in size, erythema, surface coverage silvery white squama, clear border, is apt to occur in scalp, extremity stretch side and back.Male is more than women.Winter in psoriasis spring easily recurs or increases the weight of, and many alleviations summer and autumn.
Psoriasis is called psoriasis at modern medicine, is a kind of chronic dermatosis of common easy recurrence.Its sickness rate is in recent years in obviously raising trend.According to investigations, the sickness rate white people of this disease in crowd are apparently higher than yellow, and black race takes second place.As U.S.'s investigation in recent years, its sickness rate is 2.6%, and patient reaches 600-700 ten thousand people, far away higher than China.Because of this sick obstinate refractory, be still listed in the important subject in department of dermatologry field, the world today.In the national psoriasis control cooperation meeting held in recent years, participant expert unanimously thinks " traditional Chinese medical science and the combination of Chinese and Western medicine prevent and treat psoriatic direction, and doctor trained in Western medicine anticarcinogen and hormone medicine have serious side effect, should avoid using as far as possible ".
One, psoriasis (psoriasis) typing and Clinical symptoms
Clinically generally be divided into homeliness type, pustule type, arthropathica and erythrodermic Four types.
(1) homeliness type psoriasis (psoriasis) homeliness type psoriasis is type the most common clinically.From the beginning of being red papules or maculopapule, expand gradually later or mutually merge, form clear-cut patch, surface coverage silvery white squama, appears smooth thin film after striking off squama gently, then can occur multiple tiny petechia after scraping.Above-mentioned squama, thin film and petechial hemorrhage are three large Clinical symptoms of this disease.This disease can betide any position of health, and symmetrically property distribution, is apt to occur in knee joint, elbow joint stretches side and head, and finger (toe) first of a few patients is point-like (thimble shape) depression.There are Acute Advancement phase, resting stage and paracmasis clinically.Progressive stage: feature is erythra is some drop-wise more, and color and luster is scarlet and development is rapid, and squama is more, easily comes off, and has pruritus to feel more.Normal skin is as after being subject to wound etc. and stimulating, and can secondary be psoriasis skin lesion, medical science be referred to as isomorphic response.Resting stage: the state of an illness is held in quiescent phase, occur without new rash, old rash also loses and disappears.Catagen: erythra reduces, fades away.After deflorescence, temporary hypopigmentation or calm speckle can be left over.
(2) pustule type psoriasis (psoriasis), is divided into general property, limit office property amphitypy.
1. generalized pustular psoriasis rare clinical.The morbidity of this type sharply, has general malaise and waits General Symptoms and leukocytosis with the high heat of tension and relaxation.Skin lesion onset is acute inflammation erythema, and surface has most intensive syringe needle aseptic shallow at property pimple to foxtail millet grain size yellow-white.Pustule can expand and merge formation " pus paste " shape.Often involve vast surface, even can expand and prolong whole body.Its cause of disease because of many with the agent of psoriasis vulgaris long-term taking corticosteroid after, drug withdrawal and falling ill suddenly, or with infect, medicine irritation is relevant.The primary disease state of an illness is heavier, and often in cyclic recurrence, prognosis is poor.
2. pustular psoriasis,localized's (psoriasis), also known as palmoplantar pustulosis, is limited to the palm sole of the foot more, and be everlasting large hypothenar or sufficient sole of the foot portion most faint yellow syringe needle occur in batch to the large pimple of foxtail millet grain, substrate flushing.About break through 1 ~ 2 week pustule, incrustation, desquamation.Under squama, there is pimple again later, time light time heavy.Consciously to itch or pain.Can fingernail be involved, in muddy plump, have ridge shape to swell.Other positions of patient body Chang Kejian has psoriatic lesion.Also have and first send out in the palm sole of the foot, after repeatedly recurrent exerbation, change a general property person into.
3. Acropustulosis is psoriatic rare type, and be characterized in the far-end being apt to occur in finger and toe, Acropustulosis is often secondary to wound and the infection of local skin.Patient has pain and dysfunction, refers to that distortion can appear in toenail, has bone destruction at several cases.Always comparatively thorny to the psoriatic treatment of this type, the medicine such as coal tar preparation, oral retinal is sometimes effective to Acropustulosis.
(3) arthropathica psoriasis (psoriasis), has another name called arthritic psoriasis, is often secondary to after homeliness type psoriasis or psoriasis repeatedly worsen repeatedly, also can first occur joint symptoms or with pustular psoriasis and erythrodermic psoriasis concurrent.Joint symptoms and psoriasis skin lesion have parallel relation, and primary disease is more common in male.Clinical principal character is have history of psoriasis or the asymmetry periphery polyarthritis concurrent with psoriasis, involves distal end Minor articulus, with the infringement of finger (toe) first.
Treatment psoriasis is by holding up spleen with lung moistening, and lung moistening is to adjust liver, nourishing YIN and benefiting blood, and blood circulation promoting and blood stasis dispelling maintains the balance of human internal environment, and human activin spontaneous recovery potential, eliminates psoriasic potential risk factor in invisible, thus reach the object for the treatment of both the principal and secondary aspects of a disease simultaneously.
Patent retrieval has a kind of ointment and lozenge for the treatment of psoriasis.Its constituent is Rhizoma Coptidis, Cortex Phellodendri, favus skin, sulfur are representative side, and this product not only has therapeutic effect to psoriasis and, scabies sick to rosacea, vitiligo, local pruritus also has certain therapeutic effect.Without any side effects.
Summary of the invention
In order to utilize treatment by Chinese herbs psoriasis, the present invention proposes one and being used for the treatment of psoriasic Chinese medicine.The technical scheme of this Chinese medicine is: be made up of Herba Taraxaci, Radix Scrophulariae, Rhizoma Zingiberis Recens silkworm, Zaocys, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Sophorae Flavescentis, Cortex Dictamni, each 5 ~ 30 grams of Radix Glycyrrhizae.Oral.
Good effect, by the oral treatment by Chinese herbs test of the present invention of 41 routine psoriatic, through statistics, cure rate accounts for 75.6%, alleviates and alleviates rate and account for 14.6%.Suitable to the psoriasic oral Chinese medicine application for the treatment of.
Detailed description of the invention
Be made up of Herba Taraxaci, Radix Scrophulariae, Rhizoma Zingiberis Recens silkworm, Zaocys, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Sophorae Flavescentis, Cortex Dictamni, each 5 ~ 30 grams of Radix Glycyrrhizae.
Function: removing toxic substances is dispeled the wind, blood stasis dispelling softening the hard mass.Be applicable to psoriasis.
The pharmacological action of institute's combined traditional Chinese medicine:
Herba Taraxaci
Nature and flavor: sweet, micro-hardship, cold.
Gui Jing: return liver, stomach warp.
Effect: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.
Cure mainly: upper respiratory tract infection, eye conjunctivitis, mumps, hyperglycemia, acute mastitis swells and ache, gastritis, dysentery, hepatitis, gallbladder assists inflammation, acute appendicitis, urinary system infection, pelvic inflammatory disease, carbuncle furuncle furuncle, pharyngitis, controls acute mastitis, lymphadenitis, scrofula, furuncle carbuncle toxin, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, urinary tract infection.
Radix Scrophulariae
Nature and flavor: sweet in the mouth, hardship, salty, are slightly cold.
Gui Jing: return lung, stomach, kidney channel.
Effect: clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.
Cure mainly: pathogenic warmth is joined the army, cave in pericardium, maculae caused by violent heat pathogen, and consumption of YIN caused by febrile disease, crimson tongue excessive thirst, Tianjin hinder constipation, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Rhizoma Zingiberis Recens silkworm
Nature and flavor: salty, pungent, flat.
Gui Jing: enter liver, lung meridian.
Effect: expelling wind for relieving convulsion, dissipating phlegm and resolving masses.
Cure mainly: for convulsion with spasms, laryngopharynx swelling and pain, submandibular lymph nodes is scorching, facial paralysis, skin pruritus.
Zaocys
Nature and flavor: sweet are flat.
Gui Jing: return Liver Channel.
Effect: dispel the wind, dredging collateral, arresting convulsion, relieving convulsion.
Cure mainly: for rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Flos Carthami
Nature and flavor: acrid in the mouth, warm in nature.
Gui Jing: GUIXIN, Liver Channel.
Effect: latus rectum of invigorating blood circulation, eliminating stasis to stop pain.
Cure mainly: for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury, accumulation of blood, traumatic injury congestive edema.
Radix Salviae Miltiorrhizae
Nature and flavor: bitter, are slightly cold.
Gui Jing: GUIXIN, Liver Channel.
Effect: promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, clear away heart-fire relieving restlessness, nourishing blood to tranquillize the mind.
Cure mainly: menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia, hepatosplenomegaly, angina pectoris.
Radix Sophorae Flavescentis
Nature and flavor: bitter in the mouth; Cold in nature.
Gui Jing: liver, kidney, large intestine, small intestine meridian, bladder, heart channel, urinary bladder channel.
Effect: heat clearing and damp drying; Wind dispelling insecticide.
Cure mainly: main damp-heat dysentery, discharging fresh blood stool, jaundice, dysuria, edema, leukorrhagia, pudendal pruritus, scabies, leprosy, skin pruritus, noxious dampness skin infection.
Cortex Dictamni
Nature and flavor: bitter salty, cold.
Gui Jing: enter spleen, stomach warp.
Effect: dispel the wind, dampness, heat clearing away, removing toxic substances.
Cure mainly: control wind heat sore, scabies, itchy skin eruption, rheumatic arthralgia, jaundice.
Radix Glycyrrhizae
Nature and flavor: property is put down, sweet in the mouth.
Gui Jing: return 12 warps.
Effect: invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
Cure mainly: for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Synergism between medicine:
Utilize Herba Taraxaci heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, Radix Scrophulariae clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing, Rhizoma Zingiberis Recens silkworm expelling wind for relieving convulsion, dissipating phlegm and resolving masses, Zaocys dispels the wind, dredging collateral, arresting convulsion, relieving convulsion, Flos Carthami is invigorated blood circulation latus rectum, eliminating stasis to stop pain, Radix Salviae Miltiorrhizae promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, clear away heart-fire relieving restlessness, nourishing blood to tranquillize the mind, Radix Sophorae Flavescentis heat clearing and damp drying, Cortex Dictamni dispels the wind, dampness, heat clearing away, removing toxic substances, Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, synergism between coordinating the actions of various ingredients in a prescription, reach heat-clearing and toxic substances removing, eliminating stasis to stop pain, dispel the wind, the effect of dredging collateral, to due to blockage of main and collateral channels, the psoriasis that heat in blood poison is sent out and caused produces therapeutic effect.
Clinical trial case is illustrated:
1, psoriasis vulgaris patient outcomes.This type psoriasis is from the beginning of being red papules or maculopapule, and expand gradually later or mutually merge, form clear-cut patch, surface coverage silvery white squama, appears smooth thin film after striking off squama gently, then can occur multiple tiny petechia after scraping.
Adopt treatment by Chinese herbs 5 of the present invention example property psoriatic usually, take medicine 3 times at every turn, each 15 grams, after taking medicine respectively 9 months, carry out treatment effectiveness evaluation, wherein healing person 3 example, disease alleviator 2 example.Wherein disease alleviator shows as affected areas area and reduces, and protruding reduces, and part erythema disappears, and scratchyly feels to alleviate.Illustrate and create therapeutic effect.
2, pustular psoriasis patient outcomes.This type psoriasis is limited to the palm sole of the foot more, and be everlasting large hypothenar or sufficient sole of the foot portion most faint yellow syringe needle occur in batch to the large pimple of foxtail millet grain, substrate flushing.About break through 1 ~ 2 week pustule, incrustation, desquamation.Under squama, there is pimple again later, time light time heavy.Consciously to itch or pain.
Adopt the routine patient for the treatment of by Chinese herbs 16 of the present invention, take medicine every day 3 times, each 20 grams, take 12 months courses for the treatment of respectively, take medicine after arriving the setting time limit, carry out effect observation and analysis, healing person 10 example, alleviate alleviation person 4 example, DeGrain person 2 example.Wherein healing person's skin recovers normal, and alleviation person's affected part area reduces, and symptom alleviates.Still there is symptom in not obvious person, and skin returns to form not obvious.Illustrate and create therapeutic effect.
3, arthropathica curing psoriasis effect.The type psoriasis has another name called arthritic psoriasis, is often secondary to after homeliness type psoriasis or psoriasis repeatedly worsen repeatedly, also can first occur joint symptoms or with pustular psoriasis and erythrodermic psoriasis concurrent.
20 routine patients are selected to carry out medication treatment test, patient takes medicine 3 every day, each 20 grams, take medicine continuously 12 months, after reaching the time limit of taking medicine, carry out patient's access, patient generally reflects that arthritic symptom disappears, and Folium Styracis Suberifoliae transfers brown to, and skin bulge portions turn is parallel with normal skin consistent, wherein healing person 18 is routine completely, not obvious person 2 example.Illustrate and create therapeutic effect.
According to dissimilar psoriatic's ongoing disease degree, increase or reduce dose and medicine time, cure rate increases, and reaches the effect of healing or Control in recurring completely.
Therapeutic effect is added up:
By 41 psoriasis vulgaris, pustular psoriasis and psoriasis arthropathica patient treatment test effect statistics, wherein cure rate reaches 31 examples, alleviates and alleviates rate and reach 6 examples, DeGrain person 4 example.Through statistics, cure rate accounts for 75.6%, and alleviate and alleviate rate and account for 14.6%, DeGrain rate accounts for 9.75%.
By therapeutic test and statistical effect, can prove that the present invention treats psoriasic Chinese medicine and has obvious therapeutic effect, evident in efficacy compared with other treats psoriasic Chinese medicine, can as the application in TCM of the multiple psoriasis disease for the treatment of.

Claims (1)

1. be used for the treatment of a psoriasic Chinese medicine, get Herba Taraxaci, Zaocys, Flos Carthami, Radix Salviae Miltiorrhizae, Radix Sophorae Flavescentis, Cortex Dictamni, each 5 ~ 30 grams of Radix Glycyrrhizae, it is characterized in that: in prescription, be also added with Radix Scrophulariae 5 ~ 30 grams and Rhizoma Zingiberis Recens silkworm 5 ~ 30 grams.
CN201210243899.0A 2012-07-16 2012-07-16 One is used for the treatment of psoriasic Chinese medicine Expired - Fee Related CN102772561B (en)

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1107734A (en) * 1994-12-08 1995-09-06 田振华 "Keyinling" - Chinese patent medicine for psoriasis
CN101698045A (en) * 2009-11-23 2010-04-28 赵霞 Traditional Chinese medicine powder for treating psoriasis and preparation method
CN101780216A (en) * 2010-02-26 2010-07-21 杨延珍 Medicine for treating psoriasis
CN101897871A (en) * 2010-07-20 2010-12-01 谭振国 Traditional Chinese medicine for treating psora
CN102512617A (en) * 2011-12-22 2012-06-27 蔡艳梅 Chinese herbal preparation for treating psoriasis

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1107734A (en) * 1994-12-08 1995-09-06 田振华 "Keyinling" - Chinese patent medicine for psoriasis
CN101698045A (en) * 2009-11-23 2010-04-28 赵霞 Traditional Chinese medicine powder for treating psoriasis and preparation method
CN101780216A (en) * 2010-02-26 2010-07-21 杨延珍 Medicine for treating psoriasis
CN101897871A (en) * 2010-07-20 2010-12-01 谭振国 Traditional Chinese medicine for treating psora
CN102512617A (en) * 2011-12-22 2012-06-27 蔡艳梅 Chinese herbal preparation for treating psoriasis

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