CN102755575B - Radix asparagi, fructus trichosanthis and pepperweed seed powder for infant pertussis syndrome - Google Patents

Abstract

The invention relates to the field of pharmaceutical formulation and in particular to radix asparagi, fructus trichosanthis and pepperweed seed powder for infant pertussis syndrome. The radix asparagi, fructus trichosanthis and pepperweed seed powder is characterized by comprising the following crude drugs by weight percent: 7-10 percent of radix asparagi, 7-10 percent of fructus trichosanthis, 4-7 percent of ferula borealis kuan, 4-7 percent of pepperweed seed, 5-8 percent of white mulberry root-bark, 3-6 percent of mulberry leaves, 8-11 percent of reed rhizome, 6-9 percent of rhizoma anemarrhenae, 3-6 percent of radix stemonae, 6-9 percent of aster, 5-8 percent of fructus aurantii, 2-3 percent of centipede, 3-5 percent of lumbricus, 4-6 percent of schisandra chinensis, 3-5 percent of liquorice and 4-6 percent of platycodon grandiflorum. According to the invention, the 16 crude drugs are mixed and dried and grinded into fine powder, the powder is screened by using a 120-mesh sieve and is placed into a bottle for later use. The radix asparagi, fructus trichosanthis and pepperweed seed powder is used for treating acnes, has the advantage of low cost, no obvious toxic or side effect and high curative effective rate, and is not easy to relapse.

Description

The sky beach wormwood Li powder that is used for the infant pertussis syndrome

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of sky beach wormwood Li powder for the infant pertussis syndrome.

Background technology

As everyone knows, pertussis syndrome is one group of syndrome that is difficult to clinically distinguish with pertussis, claims again " class pertussis ".He is not caused by bordetella pertussis, but by due to other microorganisms that comprise virus, wherein modal is adenovirus, and other still have mycoplasma pneumoniae, parapertussis bacillus, respiratory syncytial virus, cytomegalovirus etc.Its clinical treatment, nursing, the course of disease and more after all significantly different with general respiratory tract infection existence, as can not early discovery and processing may cause severe complication.Model case can be divided into catarrhal period (1～2 week), stage of spasmodic cough (2～4 week or longer), convalescent period (4～12 week or longer).Clinical characters is paroxysmal spasmodic cough, and any little stimulation all can cause paroxysmal spasmodic cough outbreak, and cough eventually during the end with the air-breathing roar of crow sample, the vomiting gastric content is feature.The primary disease course of disease is longer, and the appearance from onset to the paroxysmal paroxysmal spasmodic cough can be with low grade fever, cough, sneeze, shed tears and weak etc. similar cold symptoms.If this phase can in time treat, can effectively control PD.Cough begins to be monophone dry cough, and heat is stepped back, cough aggravation, especially with night for very, the companion vomits behind the paroxysmal spasmodic cough.At present, clinical in specific short, treatment mainly is the doctor trained in Western medicine anti symptom treatment, uses the treatments such as antibiotics, hormone.It is especially larger to the infant difficulty to have an injection, take medicine, and easily recurrence after the drug withdrawal.

Summary of the invention

Purpose of the present invention is exactly in order to overcome above-mentioned existing technical deficiency, and a kind of sky beach wormwood Li powder for the infant pertussis syndrome is provided, and cost is low, do not have obvious toxic-side effects, and treated effect is higher, is difficult for recurrence.

The technical scheme that the present invention solves the problems of the technologies described above employing is: a kind of sky beach wormwood Li powder for the infant pertussis syndrome, it is characterized in that the crude drug composition is by weight percentage: Radix Asparagi 7～10%, Fructus Trichosanthis 7～10%, front beard 4～7%, Semen Lepidii (Semen Descurainiae) 4～7%, Cortex Mori 5～8%, Folium Mori 3～6%, Rhizoma Phragmitis 8～11%, the Rhizoma Anemarrhenae 6～9%, the Radix Stemonae 3～6%, Radix Asteris 6～9%, Fructus Aurantii 5～8%, Scolopendra 2～3%, Pheretima 3～5%, Fructus Schisandrae Chinensis 4～6%, Radix Glycyrrhizae 3～5%, Radix Platycodonis 4～6%, with the mixed oven dry of above-mentioned 16 flavor crude drug, grind and be ground into fine powder, cross 120 mesh sieves, it is for subsequent use to bottle.

The present invention is used for the treatment of a skin ulcer, and cost is low, do not have obvious toxic-side effects, and treated effect is higher, is difficult for recurrence.

The specific embodiment

The invention will be further described below in conjunction with embodiment:

Embodiment 1:

Adopting Radix Asparagi, Fructus Trichosanthis, Radix Peucedani, Semen Lepidii (Semen Descurainiae), Cortex Mori, Folium Mori, Rhizoma Phragmitis, the Rhizoma Anemarrhenae, the Radix Stemonae, Radix Asteris, Fructus Aurantii, Scolopendra, Pheretima, Fructus Schisandrae Chinensis, Radix Glycyrrhizae, Radix Platycodonis is that raw material is prepared from.Every pair of its component (% by weight) is Radix Asparagi 9.3, Fructus Trichosanthis 9.1, front beard 6.5, Semen Lepidii (Semen Descurainiae) 6.5, Cortex Mori 7.3, Folium Mori 5.3, Rhizoma Phragmitis 9.7, the Rhizoma Anemarrhenae 7.2, the Radix Stemonae 4.8, Radix Asteris 7.9, Fructus Aurantii 6.6, Scolopendra 2.4, Pheretima 4.4, Fructus Schisandrae Chinensis 4.8, Radix Glycyrrhizae 3.4, Radix Platycodonis 4.8.Get the 139 gram oven dry of above-mentioned 16 flavor raw material total amounts, grind and be ground into fine powder, cross 120 mesh sieves, it is for subsequent use to bottle.Namely make " day beach wormwood Li powder ".Infant pertussis syndrome onset begins, and cleans first and dries infant umbilicus eye position, gets about " day beach wormwood Li powder " 10 grams and places near the eyes position of umbilicus eye and umbilicus, with the near the eyes medicated powder of umbilicus eye and umbilicus of applying ointment or plaster fixedly, changes medicated powder every day once again.Get it filled powder 30 grams with 3 medicine cakes of Ovum Gallus domesticus album furnishing again, prick the number hole with toothpick.After pressing respectively Tiantu, Danzhong, Feiyu acupuncture point, again 3 medicine cakes are affixed on respectively on above-mentioned three acupuncture points, and with moxa stick moxibustion 2～3 minutes, can tolerate with infant, fixing with applying ointment or plaster respectively behind the moxa stick moxibustion.Carry out once every day, apply ointment or plaster at every turn fix 1～2 hour after, take off respectively again, seven days is a course for the treatment of, after being applied to the clinical symptoms sign and disappearing, once, uses four times next day of medicated powder being applied umbilicus again and cooperate medicine cake moxibustion three acupuncture point.

Principal agent Radix Asparagi nature and flavor of the present invention are sweet, bitter, cold, return the lung kidney channel.Have nourishing YIN to relieve dryness, the lung heat clearing effect of promoting the production of body fluid, it is sticking to be used for dryness of the lung dry cough ， Dayton expectoration, soreness of waist and knee joint, osteopyrexia and fever, interior-heat is quenched one's thirst, and hinder in calentura Tianjin, dry throat and mouth, dryness of the intestine constipation.Sweet, the little hardship of Fructus Trichosanthis nature and flavor, cold is returned lung, stomach, large intestine channel.Have clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens is moisturized the laxation effect.Be used for the cough due to lung-heat, the turbid Huang of expectorant is thick, obstruction of qi in the chest and cardialgia, blocked-up chest feeling of fullness, acute mastitis, lung abscess, acute appendicitis, constipation.The Radix Peucedani nature and flavor are bitter, hot, be slightly cold, and return lung meridian.Have lowering the adverse-rising QI to resolve phlegm, loose wind heat clearing away effect, it is full to be used for the expectorant dyspnea of heat type, and it is yellow thick to cough up phlegm, cough due to pathogenic wind-heat's abundant expectoration.The Semen Lepidii (Semen Descurainiae) nature and flavor are hot, bitter, return lung, urinary bladder channel Great Cold.Has eliminating pathogen from the lung for relieving asthma, the line water detumescence effect.Be used for sputum and stop up lung, dyspnea and cough with excessive sputum, fullness and distention in the chest and hypochondrium etc.The Cortex Mori nature and flavor are sweet, cold, return lung meridian.Has eliminating pathogen from the lung for relieving asthma, the inducing diuresis to remove edema effect.In order to dyspnea and cough due to lung-heat, edema distension oliguria, appearance skin edema.The Folium Mori nature and flavor are sweet, bitter, cold, return lung, Liver Channel.Has dispelling wind and heat pathogens, clearing away lung-heat and moistening for dryness, liver heat removing and eyesight improving effect.Be used for anemopyretic cold, lung-heat type cough, dizziness headache, conjunctival congestion is dim-sighted.Rhizoma Phragmitis is sweet in flavor and cold in property, attaches to the lung and stomach meridians, and has clearing away heat-fire, promoting the production of body fluid to quench thirst, relieving restlessness, preventing or arresting vomiting, diuresis effect.Be used for the calentura excessive thirst, cough due to lung-heat, lung abscess vomiting pus, the gastric heat sound of vomiting of vomitting, the puckery pain of pyretic stranguria.Rhizoma Anemarrhenae nature and flavor are bitter, sweet, cold, return lung, stomach, kidney channel.Has clearing away heat-fire, nourshing Yin and drynsessmoistening prescription effect.Be used for fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, the dryness of the intestine constipation.Radix Stemonae nature and flavor are sweet, bitter, tepor, return lung meridian.Has nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing delousing effect.Be used for new chronic cough and cough, pulmonary tuberculosis cough ， Dayton coughs etc.The Radix Asteris nature and flavor are hot, bitter, warm, return lung meridian.Has nourishing the lung to keep the adverse QI downward, the stopping coughing and removing phlegm effect.Be used for the abundant expectoration cough, new chronic cough is coughed the chronic cough hemoptysis.The Fructus Aurantii nature and flavor are bitter, hot, acid, be slightly cold, and return spleen, stomach warp.Has regulating the flow of QI to ease the stomach, the stagnant relieving distension effect of row.Be used for the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion stops in the phlegm retention, visceroptosis.The Scolopendra nature and flavor are hot, warm, poisonous, return Liver Channel.Have relieve dizziness, high fever, infantile convulsions, epilepsy, etc. relieving convulsion, removing obstruction in the collateral to relieve pain, merit poison mass-dissipating efficacy.Be used for liver-wind stirring up internally, spasm is twitched, infantile convulsion etc.The Pheretima nature and flavor are salty, cold, return liver, spleen, urinary bladder channel.Have the heat clearing away arresting convulsion, collateral dredging is relievingd asthma, the diuresis effect.Be used for unconsciousness due to high fever, infantile convulsion is twitched, joint addiction pain, and numb limbs and tense tendons, hemiplegia, lung is swollen breathes with cough the edema oliguria.The Fructus Schisandrae Chinensis nature and flavor are sour, sweet, warm, return lung, the heart, kidney channel.It is astringent or styptic treatment for spontaneous sweating to have convergence, supplementing QI for promoting the production of body fluid, kidney calming effect.Be used for the chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous sweating, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, palpitation and insomnia.The Radix Glycyrrhizae nature and flavor are sweet, flat.GUIXIN, lung, spleen, stomach warp.Has invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription effect.Be used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.The Radix Platycodonis nature and flavor are bitter, hot flat, return lung meridian.Have lung qi dispersing, sore-throat relieving, eliminate the phlegm, the toxin expelling effect.Be used for cough with copious phlegm, uncomfortable in chest not smooth, the pharyngalgia hoarseness, lung abscess is spat.16 flavor Chinese herbal medicine ingenious prescriptions, the science compatibility, mutual coordinative role between medicine is played the specially good effect of infant pertussis altogether.

But each raw material of the present invention also embodiment of the listed ratio of according to the form below (percentage by weight) mixing realizes that its processing technique is identical with embodiment 1.

Below in conjunction with the clinical trial that my institute carries out the present invention is done further to describe in detail:

1, case is selected: be diagnosed as from my institute over 2007～2011 years and select 66 examples, male 38 examples, women 28 examples in the pertussis syndrome infant; Wherein≤June 19 example, June～1 years old 17 example, 1～2 years old 16 example, 2～3 years old 14 example.The course of disease is the shortest 4 days, and is the longest 16 days.Its diagnosis is according to the typical clinical performance, especially spasmodic cough, and crow sample echo, vomiting three large symptoms, reference laboratories check that leukocyte obviously increases, increase as main take lymphocyte, and the etiological examination result, to differentiate with pertussis.

2, tcm diagnosis standard reference State Administration of Traditional Chinese Medicine " the disease of tcm Standardization of diagnosis and curative effect " issued.

3, Therapeutic Method: get first a recklessly Li powder of day beach wormwood ready, infant pertussis syndrome onset is made a definite diagnosis in early days (catarrhal period), and more early effect is better.Clean first and dry infant umbilicus eye position, get about " day beach wormwood Li powder " 10 grams and place near the eyes position of umbilicus eye and umbilicus, with the near the eyes medicated powder of umbilicus eye and umbilicus of applying ointment or plaster fixedly, change medicated powder every day once again.Get it filled powder 30 grams with 3 medicine cakes of Ovum Gallus domesticus album furnishing again, prick the number hole with toothpick.After pressing respectively Tiantu, Danzhong, Feiyu acupuncture point, again 3 medicine cakes are affixed on respectively on above-mentioned three acupuncture points, and with moxa stick moxibustion 2～3 minutes, can tolerate with infant, fixing with applying ointment or plaster respectively behind the moxa stick moxibustion.Carry out once every day, apply ointment or plaster at every turn fix 1～2 hour after, take off respectively again, seven days is a course for the treatment of, uses three courses for the treatment of, once, uses four times next day of medicated powder being applied umbilicus again and cooperate medicine cake moxibustion three acupuncture point.

4, therapeutic effect: criterion of therapeutical effect evaluation;

Produce effects: the infant paroxysmal spasmodic cough, and cough all disappears with clinical symptoms signs such as the air-breathing roars of crow sample when stopping, and temperature recovery is normal, and numeration of leukocyte and Lymphocyte subset counting recover normal

Effectively: infant paroxysmal spasmodic cough, and cough obviously alleviates with clinical symptoms signs such as the air-breathing roars of crow sample when stopping, idol is outbreak again, the normal high value of numeration of leukocyte and Lymphocyte subset counting or a little more than normal value.

Invalid: infant clinical symptoms sign and lab testing are invalid.

5, therapeutic effect: use the present invention's 66 examples, carry out treatment effectiveness evaluation according to criterion of therapeutical effect, produce effects+effectively be total effective rate.Produce effects 49 examples, effective 14 examples, invalid 3 examples, total effective rate is 95.5%.

Claims (1)

1. sky beach wormwood Li powder that is used for the infant pertussis syndrome, it is characterized in that: the crude drug composition is by weight percentage, Radix Asparagi 7～10%, Fructus Trichosanthis 7～10%, Radix Peucedani 4～7%, Semen Lepidii (Semen Descurainiae) 4～7%, Cortex Mori 5～8%, Folium Mori 3～6%, Rhizoma Phragmitis 8～11%, the Rhizoma Anemarrhenae 6～9%, the Radix Stemonae 3～6%, Radix Asteris 6～9%, Fructus Aurantii 5～8%, Scolopendra 2～3%, Pheretima 3～5%, Fructus Schisandrae Chinensis 4～6%, Radix Glycyrrhizae 3～5%, Radix Platycodonis 4～6%, with the mixed oven dry of above-mentioned 16 flavor crude drug, grind and be ground into fine powder, cross 120 mesh sieves, it is for subsequent use to bottle.