CN102755530B - Traditional Chinese medicine composition for treating diabetic foot and application thereof - Google Patents
Traditional Chinese medicine composition for treating diabetic foot and application thereof Download PDFInfo
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- CN102755530B CN102755530B CN 201210255375 CN201210255375A CN102755530B CN 102755530 B CN102755530 B CN 102755530B CN 201210255375 CN201210255375 CN 201210255375 CN 201210255375 A CN201210255375 A CN 201210255375A CN 102755530 B CN102755530 B CN 102755530B
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Abstract
The invention relates to a traditional Chinese medicine composition for treating diabetic foot. The traditional Chinese medicine is characterized by comprising an internal medicine and an external medicine, wherein the internal medicine is prepared from 6-10g of phellodendron bark, 6-8g of gardenia, 6-10g of giant knotweed, 2-4g of rhubarb, 2-4g of figwort, 4-6g of schisandra fruit, 6-8g of radix rehmanniae preparata, 4-6g of cornel, 4-6g of sargentgloryvine stem, 2-4g of pseudo-ginseng, 4-6g of rhizoma pleionis and 4-6g of tuckahoe; and the external medicine is prepared from 1 part by weight of pseudo-ginseng powder, 1 part by weight of rhubarb powder and 1 part by weight of herba oldenlandiae power. The external medicine is evenly mixed with gromwell oil, and the mixture is externally applied onto the affected part. The invention has the beneficial effects of clearing away heat and toxic material, nourishing yin, nourishing the blood, eliminating stasis, alleviating pain, promoting tissue regeneration, promoting tissue regeneration and arresting bleeding, thereby achieving the goals of controlling the development and protecting the limbs. The traditional Chinese medicine composition can be used for treating diabetic foot in clinic according to different symptoms.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and application for the treatment of diabetic foot.
Background technology
As everyone knows, diabetic foot is the complication of diabetes, and the their early stage suffering limb is sent out cool, numbness, the swollen or pain of acid, meet cold increasing the weight of, chance is warm slightly to be subtracted, intermittent limping, and sick lower limb vein skin temperature descends, skin color is normal or pale, or dull yellowish colored skin, ecchymosis or numbness point appear in acra, or suffer from sufficient pain, amyotrophy, xerosis cutis or edema; Later stage is with PD, and toe-end foot lower limb occurs that gangrene festers, the wound surface Petiolus Trachycarpi, and pus is like powder slurry sewage, breath malodor, pus is rotten difficult de-, or after de-, granulation is dark red, and pus is rare clearly, and with the passing of time wound is not held back.The lighter is not taken seriously, and severe one can cause amputation, to the patient, brings very big misery.
Summary of the invention
The objective of the invention is in order to solve above-mentioned technical deficiency, provide good effect, short treating period, cure rate high, low and a kind of Chinese medicine composition and the application for the treatment of diabetic foot that have no side effect of cost.
Beneficial effect of the present invention is: heat-clearing and toxic substances removing, nourishing YIN and benefiting blood, stasis-dispelling and pain-killing, promoting tissue regeneration by astringents reach the purpose of controlling progress, protection limbs.Clinical often according to different pattern of syndrome determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.
For achieving the above object, a kind of Chinese medicine composition for the treatment of diabetic foot, is characterized in that the crude drug of Chinese medicine consists of by following weight proportion: oral medicine: Cortex Phellodendri 6～10g, Fructus Gardeniae 6～8g, Rhizoma Polygoni Cuspidati 6～10g, Radix Et Rhizoma Rhei 2～4g, Radix Scrophulariae 2～4g, Fructus Schisandrae Chinensis 4～6g, Radix Rehmanniae Preparata 6～8g, Fructus Corni 4～6g, Caulis Sargentodoxae 4～6g, Radix Notoginseng 2～4g, Pseudobulbus cremastrae seu pleiones 4～6g, Poria 4～6g.Medicine for external use: 1 part of Radix Notoginseng powder, 1 part of Radix Et Rhizoma Rhei powder, Herba Hedyotidis Diffusae is ground 1 part, Oleum Radix Arnebiae (Oleum Radix Lithospermi) into powder and mixes well the external application affected part.
Cortex Phellodendri hardship in Chinese medicine of the present invention, cold.Function cures mainly: heat clearing and damp drying, eliminating fire and detoxication, except the hectic fever due to YIN-deficiency clearind deficient heat.For damp-heat dysentery, jaundice, sore swollen toxin, eczema pruritus ...Modern study, Cortex Phellodendri has antiinflammatory, suppressing the hyperactive liver.Fructus Gardeniae pathogenic fire purging relieving restlessness, clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.This product bitter cold is fallen clearly, can rush down clearly three warmers pathogenic fire, eliminating heart-fire and relieving restlessness.Modern study, have antibacterial analgesic activity.Radix Et Rhizoma Rhei, gas delicate fragrance, bitter in the mouth and micro-puckery.Function cures mainly: attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, removing toxic substances, granulation promoting.The Rhizoma Polygoni Cuspidati bitter in the mouth, be slightly cold.Return liver, gallbladder, lung meridian.Function cures mainly: heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy ...Rhizoma Chuanxiong, Xin Wenxiang is dry, walks and does not keep, can go loose, the up top, mountain peak that reaches; Enter again blood system, the descending sea of blood that reaches.Function cures mainly: blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping.Radix Scrophulariae sweet in the mouth, hardship, salty; Cold nature.Return lung, stomach, kidney channel.Function cures mainly: clearing away heat and cooling blood, eliminating fire and detoxication, YIN nourishing.Fructus Schisandrae Chinensis is warm in nature; Sour in the mouth, sweet, return lung, the heart, kidney channel.Function cures mainly: restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.Thirsty for Tianjin wound, the deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.Modern study, contain abundant organic acid, vitamin, flavonoid, phytosterol and the lignan of potent reactivation arranged, and it is also one of minority medical material had concurrently essence, gas, god's three large tonifications.The Radix Rehmanniae Preparata function cures mainly: warm in nature.Return liver; Kidney channel.Function cures mainly: enrich blood moist; The benefit essence is filled out marrow.Modern study, have exudation, antiinflammatory, antifungic action.Fructus Corni sour in the mouth, puckery, tepor.Return liver, kidney channel.Liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating controlling nocturnal emission with astringent drugs reducing urination leukorrhagia stopping and only collapse hidroschesis and also have in addition promoting the production of body fluid to quench thirst.Caulis Sargentodoxae bitter in the mouth, property are put down.There is heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral, the effect of dispeling the wind.Radix Notoginseng is warm in nature, sweet in the mouth, micro-hardship.Function cures mainly: hemostasis, dissipating blood stasis, detumescence, pain relieving." jade is seized the medicine solution ": and battalion hemostasis, the clots absorbing of promoting blood circulation, clots absorbing blood and hold back fresh blood.Modern study, can promote hemopoietic, promoting tissue regeneration by removing blood stasis.Pseudobulbus cremastrae seu pleiones, function cures mainly: eliminating stagnation, blood stasis dispelling." detailed outline ": main furuncle is swollen, and the counteracting toxic substances broken skin, separate all poison.Radix Sophorae Flavescentis, function cures mainly: heat clearing and damp drying, parasite killing, diuresis.For eczema, eczema, skin pruritus, the scabies leprosy, modern study, have antitumor, blood sugar lowering, anti-allergic effects.Poria is sweet, light, property is flat, be used as medicine there is promoting diuresis to eliminate damp pathogen, the function of strengthening the spleen stomach function regulating, mind tranquilizing and the heart calming.Modern medicine study: Poria energy enhancing human body immunity function, pachyman has obvious antitumor and protects the liver dirty effect.Medicine for external use: Herba Hedyotidis Diffusae bitter in the mouth, light, cold in nature.Main effect is heat-clearing and toxic substances removing, medicinal powder for relieving pain knot, promoting urination to remove dampness.Outstanding kind treatment all kinds inflammation.Grind into powder and with Oleum Radix Arnebiae (Oleum Radix Lithospermi), mix well external application afterwards, strengthen the effect of its heat-clearing and toxic substances removing, dispersing swelling and dissipating binds.Oleum Radix Arnebiae (Oleum Radix Lithospermi) has the effect of blood circulation promoting and blood stasis dispelling, nutrition convergence.Upper all medicines match, and by Chinese medicine, treat, and bring out the best in each other.
The present invention follows the prescriptions principle of the traditional Chinese medical science, divides and is decocted in water for oral dose and medicine for external use.The present invention is through clinical verification: effective percentage is more than 90%, and cure rate is, more than 70%, to have no side effect.Taboo: Deficiency and coldness of spleen and stomach, the anorexia and loose stool person should not take Radix Et Rhizoma Rhei.The specific embodiment
Below in conjunction with implementing case, the invention will be further described:
Embodiment 1: a kind of Chinese medicine composition for the treatment of diabetic foot is characterized in that by following proportioning weighting raw materials thing: oral medicine: Cortex Phellodendri 6～10g, Fructus Gardeniae 6～8g, Rhizoma Polygoni Cuspidati 6～10g, Radix Et Rhizoma Rhei 2～4g, Radix Scrophulariae 2～4g, Fructus Schisandrae Chinensis 4～6g, Radix Rehmanniae Preparata 6～8g, Fructus Corni 4～6g, Caulis Sargentodoxae 4～6g, Radix Notoginseng 2～4g, Pseudobulbus cremastrae seu pleiones 4～6g, Poria 4～6g; Medicine for external use: 1 part of Radix Notoginseng powder, 1 part of Radix Et Rhizoma Rhei powder, Herba Hedyotidis Diffusae is ground 1 part, Oleum Radix Arnebiae (Oleum Radix Lithospermi) into powder and mixes well the external application affected part.
Embodiment 2: a kind of Chinese medicine composition for the treatment of diabetic foot is characterized in that by following proportioning weighting raw materials thing: Cortex Phellodendri 6g, Fructus Gardeniae 8g, Rhizoma Polygoni Cuspidati 6g, Radix Et Rhizoma Rhei 4g, Radix Scrophulariae 4g, Fructus Schisandrae Chinensis 4g, Radix Rehmanniae Preparata 6g, Fructus Corni 4g, Caulis Sargentodoxae 4g, Radix Notoginseng 2g, Pseudobulbus cremastrae seu pleiones 4g, Poria 4g; Medicine for external use is with embodiment 1.
Clinical efficacy is summed up:
One, we are extensive in clinical practice for many years, treat routine patients up to a hundred, and curative effect is frequently good.Taboo: for Deficiency and coldness of spleen and stomach, the anorexia and loose stool person Radix Et Rhizoma Rhei of stopping using.
Two, diagnostic criteria: the diabetes medical history is arranged, and Early manifestation is the foot numbness, anesthesia etc.The patient is due to the impact that is subject to for a long time hyperglycemia, and lower limb vascular sclerosis, vessel wall thickening, flexibility decrease, easily form thrombosis, and be combined into speckle in blood vessel, cause lower limb vascular occlusion and lower limb lesion tissue.And " foot " is centrifugal farthest dirty, the ischemia phenomenon is the most serious, thereby causes edema, blackout, rotten, downright bad.
Three, administrated method: oral medicine adds the dense decoction of decocting into of water by above all selection of crude drugs, mixing after soaking, every dose of 100ml, morning every day, late sub-service.Medicine for external use furnishing pasty state is coated with affected part, every day 1 time, each 60 minutes.
Four, efficacy evaluation:
Cure: clinical symptoms disappears fully.
Take a turn for the better: clinical symptoms is improved.
Do not heal: clinical symptoms is without improving or increasing the weight of.
Five, therapeutic effect: treatment by Chinese herbs primary disease of the present invention, cure rate is more than 70% by statistics, and effective percentage is more than 90%.
Six, model case
The clump XX, female, 62 years old.In June, 2009 is medical.The main suit suffers from diabetes 20 years, and the left foot toe is first numb, rear pain, and blue about half a year, toe blackout ulceration 3 days, eat antalgica and antibiotic medicine poor effect.Have a medical check-up: the equal ulceration of bipod skin of toe after left foot.Lab testing: fasting glucose 9.2mmol/L.The patient requires each 25 doses, for oral administration and external Chinese medicine of the present invention, and guides that the patient is careful in one's diet, glucose-lowering treatment on time, and clinical symptoms disappears fully, after half a year, does not follow up a case by regular visits to and recurs.
2. congratulate XX, man, 68 years old.In JIUYUE, 2010 is medical.The main suit suffers from diabetes 25 years, and informal dress Or Metformin In Treating diabetes toe pain still occurs 2 months, and blue more than 10 days of skin increases the weight of 3 days, antibiotic therapy 10 days, poor effect.Have a medical check-up: biped toe skin is blue, left side 2 toe skin darkenings.Lab testing: fasting glucose 8.7mmol/L.The patient requires 20 doses, the external Chinese medicine of the present invention that reaches for oral administration, and toe erythrosis profit, and guide diet, continues glucose-lowering treatment, and clinical symptoms disappears fully, does not recur again.
3. Song XX, female, 54 years old.In October, 2011 is medical.The main suit suffers from diabetes 12 years, and the medication treatment diabetes toe pain occurs more than 20 days, and toe edema, skin turn black 1 week, pharmacy buy indometacin relieve the pain the treatment 3 days, poor effect.Lab testing: fasting glucose 10.2mmol/L.The patient requires 20 doses, the external Chinese medicine of the present invention that reaches for oral administration, and guides diet, continues glucose-lowering treatment, and toe skin is gain color progressively, and clinical symptoms disappears fully, after half a year, does not follow up a case by regular visits to and recurs.
Claims (1)
1. a Chinese medicine composition for the treatment of diabetic foot, is characterized in that it is comprised of the crude drug of following proportioning: oral medicine: Cortex Phellodendri 6～10g, Fructus Gardeniae 6～8g, Rhizoma Polygoni Cuspidati 6～10g, Radix Et Rhizoma Rhei 2～4g, Radix Scrophulariae 2～4g, Fructus Schisandrae Chinensis 4～6g, Radix Rehmanniae Preparata 6～8g, Caulis Sargentodoxae 4～6g, Radix Notoginseng 2～4g, Pseudobulbus cremastrae seu pleiones 4～6g, Poria 4～6g; Medicine for external use: 1 part of Radix Notoginseng powder, 1 part of Radix Et Rhizoma Rhei powder, Herba Hedyotidis Diffusae is ground 1 part, Oleum Radix Arnebiae (Oleum Radix Lithospermi) into powder and mixes well the external application affected part.
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| CN 201210255375 CN102755530B (en) | 2012-07-15 | 2012-07-15 | Traditional Chinese medicine composition for treating diabetic foot and application thereof |
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| CN 201210255375 CN102755530B (en) | 2012-07-15 | 2012-07-15 | Traditional Chinese medicine composition for treating diabetic foot and application thereof |
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| CN102755530B true CN102755530B (en) | 2013-12-25 |
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| CN106266205A (en) * | 2016-11-03 | 2017-01-04 | 南通大学附属医院 | A kind of for promoting the middle-aged and elderly people Chinese medicine formula of diabetic foot rehabilitation |
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| CN1090193A (en) * | 1993-05-03 | 1994-08-03 | 孙志远 | The medicine and the production method of treatment diabetes |
| CN1103305A (en) * | 1993-11-27 | 1995-06-07 | 李南山 | Diabetes powder and its preparing method |
| KR100195886B1 (en) * | 1996-11-01 | 1999-06-15 | 김상조 | Pharmaceutical composition for treating diabetes mellitus |
| CN1108804C (en) * | 2000-05-19 | 2003-05-21 | 牛爱军 | Diabetes treating medicine and its prepn. method |
| CN1267144C (en) * | 2004-10-11 | 2006-08-02 | 任连智 | Compound diabetes-treating sugar-decreasing fat-reducing preparation and preparation method thereof |
| CN101129831A (en) * | 2007-08-29 | 2008-02-27 | 北京艺信堂医药研究所 | Proprietary Chinese medicine for treating diabetes urinary tract infection |
| CN101642547B (en) * | 2009-06-14 | 2011-06-01 | 李承平 | Chinese patent medicine for treating diabetes |
| CN101708295B (en) * | 2009-12-04 | 2012-01-04 | 卢速江 | Chinese medicinal preparation for treating diabetes and preparation methods thereof |
| CN102048894B (en) * | 2010-12-22 | 2013-03-13 | 陈远征 | Traditional Chinese medicine composition for treating burn and preparation method thereof |
| CN102091203B (en) * | 2011-01-19 | 2012-04-11 | 李惠斌 | External traditional Chinese medicine preparation for treating refractory wound and preparation method thereof |
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