CN102743792B - 用于增强血管通路的方法和组合物 - Google Patents

用于增强血管通路的方法和组合物 Download PDF

Info

Publication number
CN102743792B
CN102743792B CN201210246619.1A CN201210246619A CN102743792B CN 102743792 B CN102743792 B CN 102743792B CN 201210246619 A CN201210246619 A CN 201210246619A CN 102743792 B CN102743792 B CN 102743792B
Authority
CN
China
Prior art keywords
cell
implantable material
cells
implantable
cryopreservation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201210246619.1A
Other languages
English (en)
Chinese (zh)
Other versions
CN102743792A (zh
Inventor
海伦·玛丽·纽金特
埃拉扎尔·埃德尔曼
阿努帕姆·达拉尔
史蒂夫·博林杰
斯科特·埃珀利
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pervasis Therapeutics Inc
Original Assignee
Pervasis Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2005/043967 external-priority patent/WO2006062909A2/en
Application filed by Pervasis Therapeutics Inc filed Critical Pervasis Therapeutics Inc
Publication of CN102743792A publication Critical patent/CN102743792A/zh
Application granted granted Critical
Publication of CN102743792B publication Critical patent/CN102743792B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/069—Vascular Endothelial cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A61L27/3808—Endothelial cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Botany (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Prostheses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • External Artificial Organs (AREA)
CN201210246619.1A 2005-06-21 2006-06-05 用于增强血管通路的方法和组合物 Expired - Fee Related CN102743792B (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US69270805P 2005-06-21 2005-06-21
US60/692,708 2005-06-21
USPCT/US2005/043967 2005-12-06
PCT/US2005/043967 WO2006062909A2 (en) 2004-12-08 2005-12-06 Methods and compositions for enhancing vascular access

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN2006800279776A Division CN101257861B (zh) 2005-06-21 2006-06-05 用于增强血管通路的方法和组合物

Publications (2)

Publication Number Publication Date
CN102743792A CN102743792A (zh) 2012-10-24
CN102743792B true CN102743792B (zh) 2014-09-24

Family

ID=39892157

Family Applications (3)

Application Number Title Priority Date Filing Date
CN201210246619.1A Expired - Fee Related CN102743792B (zh) 2005-06-21 2006-06-05 用于增强血管通路的方法和组合物
CN2006800279776A Expired - Fee Related CN101257861B (zh) 2005-06-21 2006-06-05 用于增强血管通路的方法和组合物
CN2010102362140A Pending CN101878757A (zh) 2005-06-21 2006-06-05 用于增强血管通路的方法和组合物

Family Applications After (2)

Application Number Title Priority Date Filing Date
CN2006800279776A Expired - Fee Related CN101257861B (zh) 2005-06-21 2006-06-05 用于增强血管通路的方法和组合物
CN2010102362140A Pending CN101878757A (zh) 2005-06-21 2006-06-05 用于增强血管通路的方法和组合物

Country Status (10)

Country Link
US (2) US20090035346A1 (https=)
EP (2) EP1901680B1 (https=)
JP (2) JP5632580B2 (https=)
CN (3) CN102743792B (https=)
AU (1) AU2006262682B2 (https=)
CA (2) CA2818182C (https=)
ES (1) ES2541684T3 (https=)
IL (2) IL188263A (https=)
SG (2) SG161258A1 (https=)
WO (1) WO2007001744A2 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2926510B2 (ja) 1990-08-09 1999-07-28 京都電子工業株式会社 アンモニア濃度測定装置
DE602006014814D1 (de) 2005-04-21 2010-07-22 Massachusetts Inst Technology Materialien und verfahren zur änderung einer immunreaktion auf exogene und endogene immunogene, einschliesslich genidentischer und nicht-genidentischer zellen, gewebe oder organe
EP1901680B1 (en) 2005-06-21 2015-04-15 Shire Regenerative Medicine, Inc. Crypreservation of biocompatible material
WO2008057580A2 (en) * 2006-11-07 2008-05-15 Pervasis Therapeutics, Inc. Materials and methods for treating and managing angiogenesis-mediated diseases
WO2008057590A2 (en) * 2006-11-07 2008-05-15 Pervasis Therapeutics, Inc. Methods and compositions for modulating tissue modeling
EP2240116B1 (en) 2008-01-28 2015-07-01 Biomet 3I, LLC Implant surface with increased hydrophilicity
JP6038123B2 (ja) 2011-04-28 2016-12-07 アブラクシス バイオサイエンス， エルエルシー ナノ粒子組成物の脈管内送達およびそれらの使用
CN102763642B (zh) * 2012-08-14 2014-04-02 郑州赛英科干细胞技术有限公司 一种冷冻保护液以及冷冻保存人胎盘羊膜和绒毛膜的方法
WO2015181245A1 (en) * 2014-05-27 2015-12-03 Novahep Ab Bioengineered allogeneic valve
EP3267951A4 (en) * 2015-03-10 2018-12-19 Stent Tek Limited Surgical system, device and methods of use thereof for the percutaneous creation of an arteriovenous fistula (avf)
US11389622B1 (en) * 2017-11-13 2022-07-19 Simon B. Rayhanabad Patch for providing dialysis
US12017032B1 (en) 2017-11-13 2024-06-25 Sbr Innovations, Llc Arteriovenous graft and method of using thereof
WO2019152799A1 (en) 2018-02-02 2019-08-08 University Of Louisville Research Foundation, Inc. Sutureless graft anastomotic quick connect system
EP3843798A1 (en) * 2018-08-31 2021-07-07 Wisconsin Alumni Research Foundation Generating arterial endothelial cell-seeded vascular grafts
US12310836B2 (en) 2020-03-03 2025-05-27 Akeo Hagiwara Vein cover
CN115376392B (zh) * 2022-08-18 2024-04-26 昆明理工大学 主动脉老化对血管生物力学影响的模拟装置及方法
EP4439070B1 (de) * 2023-03-27 2025-12-03 Siemens Healthcare Diagnostics Products GmbH Automatisches analysesystem
CN120227529B (zh) * 2025-05-29 2025-08-12 鼎科医疗技术（苏州）有限公司 一种血管外支架

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766584A (en) * 1995-06-02 1998-06-16 Massachusetts Institute Of Technology Inhibition of vascular smooth muscle cell proliferation with implanted matrix containing vascular endothelial cells
US6328762B1 (en) * 1999-04-27 2001-12-11 Sulzer Biologics, Inc. Prosthetic grafts
WO2002062335A2 (en) * 2001-01-16 2002-08-15 Vascular Therapies, Llc Implantable device containing resorbable matrix material and anti-proliferative drugs for preventing or treating failure of hemodialysis vascular access and other vascular grafts
WO2004002549A1 (en) * 2002-06-28 2004-01-08 Novartis Ag Use of organic compounds

Family Cites Families (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418691A (en) * 1981-10-26 1983-12-06 Massachusetts Institute Of Technology Method of promoting the regeneration of tissue at a wound
US4787900A (en) * 1982-04-19 1988-11-29 Massachusetts Institute Of Technology Process for forming multilayer bioreplaceable blood vessel prosthesis
IL78950A (en) 1985-06-06 1991-12-15 Univ Jefferson Coating for prosthetic devices
US4820626A (en) * 1985-06-06 1989-04-11 Thomas Jefferson University Method of treating a synthetic or naturally occuring surface with microvascular endothelial cells, and the treated surface itself
US4732155A (en) * 1985-08-27 1988-03-22 The Children's Medical Center Corporation Implantable chemoattractant system
US5863531A (en) * 1986-04-18 1999-01-26 Advanced Tissue Sciences, Inc. In vitro preparation of tubular tissue structures by stromal cell culture on a three-dimensional framework
US5736372A (en) * 1986-11-20 1998-04-07 Massachusetts Institute Of Technology Biodegradable synthetic polymeric fibrous matrix containing chondrocyte for in vivo production of a cartilaginous structure
CA1340581C (en) * 1986-11-20 1999-06-08 Joseph P. Vacanti Chimeric neomorphogenesis of organs by controlled cellular implantation using artificial matrices
US6309635B1 (en) * 1986-11-20 2001-10-30 Children's Medical Center Corp. Seeding parenchymal cells into compression resistant porous scaffold after vascularizing in vivo
US5567612A (en) * 1986-11-20 1996-10-22 Massachusetts Institute Of Technology Genitourinary cell-matrix structure for implantation into a human and a method of making
US5759830A (en) * 1986-11-20 1998-06-02 Massachusetts Institute Of Technology Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo
US5073492A (en) * 1987-01-09 1991-12-17 The Johns Hopkins University Synergistic composition for endothelial cell growth
US5145769A (en) * 1987-08-21 1992-09-08 Cryolife Inc. Method for cryopreserving blood vessels
US5202120A (en) * 1987-09-11 1993-04-13 Case Western Reserve University Methods of reducing glial scar formation and promoting axon and blood vessel growth and/or regeneration through the use of activated immature astrocytes
US4945086A (en) 1988-05-03 1990-07-31 The Board Of Trustees Of The Leland Stanford Junior University Smooth muscle cell growth inhibitor
US5575815A (en) * 1988-08-24 1996-11-19 Endoluminal Therapeutics, Inc. Local polymeric gel therapy
US5843156A (en) * 1988-08-24 1998-12-01 Endoluminal Therapeutics, Inc. Local polymeric gel cellular therapy
CH676195A5 (https=) * 1988-10-07 1990-12-28 Sulzer Ag
JPH03133901A (ja) * 1989-10-19 1991-06-07 Osaka Gas Co Ltd 生体細胞の凍結保存方法
WO1991007154A1 (en) * 1989-11-13 1991-05-30 President And Fellows Of Harvard College EXTRALUMINAL REGULATION OF THE GROWTH AND REPAIR OF TUBULAR STRUCTURES ιIN VIVO
US5527532A (en) * 1989-11-13 1996-06-18 President And Fellows Of Harvard College Extraluminal regulation of the growth and repair of tubular structures in vivo
US5540928A (en) * 1991-02-27 1996-07-30 President And Fellows Of Harvard College Extraluminal regulation of the growth and repair of tubular structures in vivo
CA2071137A1 (en) * 1991-07-10 1993-01-11 Clarence C. Lee Composition and method for revitalizing scar tissue
EP1041142A3 (en) 1991-07-15 2007-10-24 Oklahoma Medical Research Foundation Universal donor cells
US5336615A (en) 1992-01-06 1994-08-09 Yale University Genetically engineered endothelial cells exhibiting enhanced migration and plasminogen activator activity
JPH0646840A (ja) * 1992-08-04 1994-02-22 Nippon Zenyaku Kogyo Kk 細胞凍結保存液
US5399665A (en) * 1992-11-05 1995-03-21 Massachusetts Institute Of Technology Biodegradable polymers for cell transplantation
US6491938B2 (en) * 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5981568A (en) * 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
GB9306449D0 (en) * 1993-03-29 1993-05-19 Nat Heart Research Fund Tissue equivalents
US5709854A (en) * 1993-04-30 1998-01-20 Massachusetts Institute Of Technology Tissue formation by injecting a cell-polymeric solution that gels in vivo
US5645829A (en) * 1993-06-18 1997-07-08 Beth Israel Hospital Association Mesothelial cell gene therapy
US6176874B1 (en) * 1993-10-18 2001-01-23 Masschusetts Institute Of Technology Vascularized tissue regeneration matrices formed by solid free form fabrication techniques
US6608182B1 (en) * 1994-03-08 2003-08-19 Human Genome Sciences, Inc. Human vascular endothelial growth factor 2
EP0757562A1 (en) 1994-04-29 1997-02-12 W.L. Gore & Associates, Inc. Improved blood contact surfaces using endothelium on a subendothelial extracellular matrix
US5834029A (en) * 1994-07-20 1998-11-10 Cytotherapeutics, Inc. Nerve guidance channel containing bioartificial three-dimensional hydrogel extracellular matrix derivatized with cell adhesive peptide fragment
US6911216B1 (en) * 1994-10-12 2005-06-28 Genzyme Corporation Targeted delivery via biodegradable polymers
JPH10509696A (ja) * 1994-10-12 1998-09-22 フォーカル， インコーポレイテッド 生分解性ポリマーを介する標的化送達
US5914268A (en) * 1994-11-21 1999-06-22 National Jewish Center For Immunology & Respiratory Medicine Embryonic cell populations and methods to isolate such populations
US6281015B1 (en) * 1994-12-16 2001-08-28 Children's Medical Center Corp. Localized delivery of factors enhancing survival of transplanted cells
US5716404A (en) * 1994-12-16 1998-02-10 Massachusetts Institute Of Technology Breast tissue engineering
US5855610A (en) * 1995-05-19 1999-01-05 Children's Medical Center Corporation Engineering of strong, pliable tissues
US6615071B1 (en) * 1995-09-20 2003-09-02 Board Of Regents, The University Of Texas System Method and apparatus for detecting vulnerable atherosclerotic plaque
US5897987A (en) * 1996-03-25 1999-04-27 Advanced Reproduction Technologies, Inc. Use of arabinogalactan in cell cryopreservation media
US6886568B2 (en) * 1998-04-08 2005-05-03 The Johns Hopkins University Method for fabricating cell-containing implants
CA2351671A1 (en) * 1998-11-24 2000-06-08 Regents Of The University Of Minnesota Transgenic circulating endothelial cells
US6387116B1 (en) * 1999-06-30 2002-05-14 Pharmasonics, Inc. Methods and kits for the inhibition of hyperplasia in vascular fistulas and grafts
US6461631B1 (en) * 1999-11-16 2002-10-08 Atrix Laboratories, Inc. Biodegradable polymer composition
WO2001062241A1 (en) * 2000-02-23 2001-08-30 Smithkline Beecham Corporation Method for the prevention or reduction of vascular access dysfunction
AU4566001A (en) * 2000-03-13 2001-09-24 Biocure Inc Embolic compositions
ATE362382T1 (de) * 2000-03-15 2007-06-15 Orbusneich Medical Inc Beschichtung welche ein anhaften von endothelzellen stimuliert
US20030118982A1 (en) 2000-03-24 2003-06-26 Naoka Yamamoto Method of preserving tissue equivalent and tissue equivalent preserved in frozen state
US6506398B1 (en) * 2000-04-28 2003-01-14 Hosheng Tu Device for treating diabetes and methods thereof
US20020042131A1 (en) * 2000-06-09 2002-04-11 Organ Recovery Systems Cryopreservation method using cryoprotective composition of propanediol and a vehicle solution
EP1301197A2 (en) 2000-07-21 2003-04-16 The Board Of Regents, The University Of Texas System Device providing regulated growth factor delivery for the regeneration of peripheral nerves
WO2002028387A1 (en) * 2000-10-03 2002-04-11 Oncopharmaceutical, Inc. Inhibitors of angiogenesis and tumor growth for local and systemic administration
JP2002200161A (ja) * 2000-10-24 2002-07-16 Menicon Co Ltd 培養皮膚代替物の製造方法およびそれにより得られる培養皮膚代替物
US6565601B2 (en) * 2000-11-15 2003-05-20 Micro Therapeutics, Inc. Methods for vascular reconstruction of diseased arteries
AU2002246747A1 (en) * 2000-12-27 2002-08-06 Ortec International, Inc. Processes for making cryopreserved composite living constructs and products resulting therefrom
US6723131B2 (en) * 2001-02-28 2004-04-20 The Cleveland Clinic Foundation Composite bone marrow graft material with method and kit
AU2002330131A1 (en) 2001-09-28 2003-04-07 Goldberg, Eugene, P. Biopolymer and biopolymer-cell compositions for nerve tissue repair
US7297540B2 (en) * 2002-01-15 2007-11-20 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of generating tissue using devitalized, acellular scaffold matrices derived from micro-organs
US20040047843A1 (en) * 2002-02-12 2004-03-11 Uab Research Foundation Method for spinal cord reconnection
WO2003083044A2 (en) * 2002-03-25 2003-10-09 Condros, Inc. Tissue analogs for in vitro testing and method of use therefor
US20050008629A1 (en) * 2002-05-08 2005-01-13 Interpore Orthopaedics, A Delaware Corporation Encapsulated AGF cells
FR2845691B1 (fr) * 2002-10-10 2004-12-10 Centre Nat Rech Scient Nouvelles cellules endotheliales, anticorps diriges contre ces cellules et leur utilisation, notamment pour le criblage de substances inhibant l'angiogenese
US20040156878A1 (en) * 2003-02-11 2004-08-12 Alireza Rezania Implantable medical device seeded with mammalian cells and methods of treatment
WO2004111207A1 (en) * 2003-06-09 2004-12-23 Centelion Multicellular in vitro model of angiogenesis and methods for using the same
US8192348B2 (en) * 2003-07-01 2012-06-05 Regents Of The University Of Minnesota Engineered blood vessels
GB0322789D0 (en) * 2003-09-30 2003-10-29 Lifeforce Group Plc Blood pack for leukocyte banking
US20050106554A1 (en) * 2003-11-19 2005-05-19 Palecek Sean P. Cryopreservation of pluripotent stem cells
US8067368B2 (en) * 2004-01-27 2011-11-29 The Ohio State University Research Foundation Vascular endothelial growth factors and methods of their use
WO2005108559A2 (en) * 2004-04-23 2005-11-17 Bioe, Inc. Multi-lineage progenitor cells
FR2869533B1 (fr) 2004-05-03 2006-07-28 Sedat Sa Seringue pour interventions medicales et necessaire de reconstitution de substances extemporanees comportant une telle seringue
US7842304B2 (en) 2004-10-29 2010-11-30 Nexeon Medsystems, Inc. Methods and apparatus for treating an injured nerve pathway
WO2006062871A2 (en) 2004-12-08 2006-06-15 Pervasis Therapeutics, Inc. Materials and methods for minimally-invasive administration of a cell-containing flowable composition
WO2006062909A2 (en) * 2004-12-08 2006-06-15 Pervasis Therapeutics, Inc. Methods and compositions for enhancing vascular access
ES2490610T3 (es) * 2004-12-08 2014-09-04 Shire Regenerative Medicine, Inc. Materiales y métodos para la administración mínimamente invasiva de una composición fluida que contiene células
DE602006014814D1 (de) 2005-04-21 2010-07-22 Massachusetts Inst Technology Materialien und verfahren zur änderung einer immunreaktion auf exogene und endogene immunogene, einschliesslich genidentischer und nicht-genidentischer zellen, gewebe oder organe
GB0509845D0 (en) 2005-05-13 2005-06-22 Btg Int Ltd Preparation of therapeutic foam
EP1901680B1 (en) 2005-06-21 2015-04-15 Shire Regenerative Medicine, Inc. Crypreservation of biocompatible material
WO2007047425A1 (en) 2005-10-12 2007-04-26 Cellular Bioengineering, Inc. Resorbable cornea button
US7882863B2 (en) * 2005-10-19 2011-02-08 Cd Solutions, Llc Apparatus and method for mixing and transferring medications
EP1951344B1 (en) * 2005-11-07 2014-05-28 Industrie Borla SpA Vented safe handling vial adapter

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766584A (en) * 1995-06-02 1998-06-16 Massachusetts Institute Of Technology Inhibition of vascular smooth muscle cell proliferation with implanted matrix containing vascular endothelial cells
US6328762B1 (en) * 1999-04-27 2001-12-11 Sulzer Biologics, Inc. Prosthetic grafts
WO2002062335A2 (en) * 2001-01-16 2002-08-15 Vascular Therapies, Llc Implantable device containing resorbable matrix material and anti-proliferative drugs for preventing or treating failure of hemodialysis vascular access and other vascular grafts
WO2004002549A1 (en) * 2002-06-28 2004-01-08 Novartis Ag Use of organic compounds

Also Published As

Publication number Publication date
EP2361591A3 (en) 2011-12-21
SG161258A1 (en) 2010-05-27
EP1901680A2 (en) 2008-03-26
ES2541684T3 (es) 2015-07-23
CN102743792A (zh) 2012-10-24
WO2007001744B1 (en) 2007-12-21
US9023377B2 (en) 2015-05-05
AU2006262682B2 (en) 2012-07-05
CN101257861A (zh) 2008-09-03
CN101878757A (zh) 2010-11-10
IL220806A (en) 2014-05-28
WO2007001744A2 (en) 2007-01-04
CA2818182C (en) 2015-04-14
US20130210142A1 (en) 2013-08-15
JP2012166084A (ja) 2012-09-06
AU2006262682A1 (en) 2007-01-04
IL188263A0 (en) 2009-02-11
CA2818182A1 (en) 2007-01-04
CA2612751A1 (en) 2007-01-04
US20090035346A1 (en) 2009-02-05
IL188263A (en) 2014-05-28
EP1901680B1 (en) 2015-04-15
EP2361591A2 (en) 2011-08-31
CN101257861B (zh) 2012-12-05
SG195537A1 (en) 2013-12-30
WO2007001744A3 (en) 2007-10-04
JP2008546406A (ja) 2008-12-25
JP5632580B2 (ja) 2014-11-26
IL220806A0 (en) 2012-08-30

Similar Documents

Publication Publication Date Title
AU2005314263B2 (en) Methods and compositions for enhancing vascular access
US9023377B2 (en) Methods and compositions for enhancing vascular access
US20100204783A1 (en) Methods and compositions for enhancing vascular access
CN101076360B (zh) 含细胞的可流动组合物的最小侵入性给药的材料和方法
WO2006062909A2 (en) Methods and compositions for enhancing vascular access
AU2012238220B2 (en) Methods and compositions for enhancing vascular access
AU2011211370B2 (en) Methods and compositions for enhancing vascular access
HK1174859A (en) Methods and compositions for enhancing vascular access
HK1143517A (en) Compositions and their use for enhancing vascular access
HK1178466A (en) Methods and compositions for enhancing vascular access
HK1112429B (en) Compositions and their use for enhancing vascular access

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: SHIRE REGENERATIVE MEDICAL COMPANY

Free format text: FORMER OWNER: PERVASIS THERAPEUTICS INC.

Effective date: 20130403

C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20130403

Address after: American California

Applicant after: Pervasis Therapeutics Inc.

Address before: Massachusetts, USA

Applicant before: Pervasis Therapeutics Inc.

REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 1174859

Country of ref document: HK

C14 Grant of patent or utility model
GR01 Patent grant
REG Reference to a national code

Ref country code: HK

Ref legal event code: WD

Ref document number: 1174859

Country of ref document: HK

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140924

Termination date: 20200605

CF01 Termination of patent right due to non-payment of annual fee