CN102743504A - Chinese medicinal composition for reducing weight and lowering lipid - Google Patents
Chinese medicinal composition for reducing weight and lowering lipid Download PDFInfo
- Publication number
- CN102743504A CN102743504A CN2012102593178A CN201210259317A CN102743504A CN 102743504 A CN102743504 A CN 102743504A CN 2012102593178 A CN2012102593178 A CN 2012102593178A CN 201210259317 A CN201210259317 A CN 201210259317A CN 102743504 A CN102743504 A CN 102743504A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- thick paste
- preparation
- fat
- food
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to the field of medicaments, in particular to a Chinese medicinal composition for controlling and/or reducing fat content, a preparation and a food. The Chinese medicinal composition is prepared from natural edible raw materials such as mango, lucid ganoderma, fructus crataegi, chrysanthemum and barbary wolfberry fruit, and can be used for regulating the activity of human body metabolic enzymes and accelerating oxidative decomposition of in-vivo fat tissues, and has the effects of improving the body status of an overweight person, and reducing fat and weight. The Chinese medicinal composition has a good curative effect on control and/or reduction of fat content, acts durably and stably, and is free from untoward reactions. As proved by acute toxicity research test, the Chinese medicinal composition, the preparation and the food provided by the invention are free from toxic and side effects.
Description
Technical field
The present invention relates to drug world, particularly a kind of Chinese medicine composition of Weight-reducing and lipid-lowering, preparation and food.
Background technology
Fat (Obesity) is that body fat quantity increases or the volume hypertrophy causes the body weight pathological state of body weight more than 20% that be above standard.In recent years, no matter in developed country or developing country, the obesity sickness rate all is the trend of rising, has become the primary health problem pendulum in the whole world in face of people.The report of World Health Organization (WHO) points out that the whole world has 2.5 hundred million adult to suffer from obesity approximately at present, and at least 5 hundred million Genus Homos are in overweight in addition.And in population of adolescent, fat trend is more obvious, becomes our great healthy hidden danger of future generation.According to incompletely statistics, the surprising speed increment of global obesity to double in per 5 years, the direct or indirect death toll that annual obesity is facilitated has reached 300,000.The fat consequence that spreads health, economy and the social mentality aspect brought is serious.Obesity is not only single disease, and it also can cause the unusual of a plurality of systems of whole body through the effect of organism metabolism, becomes " arch-criminal " of multiple disease.It has increased the probability of happening of type, hypertension, dyslipidemias, ischemic cardiomyopathy, cerebrovascular, cholelithiasis and some cancerous protuberance, osteoarthritis, polycystic ovarian syndrome.The overweight people compares with non-overweight people, and its sickness rate significantly increases, and to diabetes, the dangerous maximum of cardiovascular disease, also is to cause its main causes of death especially.
Obesity is a kind of complicacy, overdetermined Metabolic disorder disease, all is possibly cause fat factor as gene, hormone, environment, life style and the diet of regulating the energy balance.Essentially, obesity comes from the equilibrated destruction between food intake and the energy expenditure.
The medicine of treatment of obesity at present mainly contains chemical medicine, two types of appetrol of plant amedica.Chemistry medicine mechanism of action can be divided into 3 types: central appetite suppressant (norepinephrine agonist, serotonin agonist, norepinephrine-serotonin agonist etc.), short energy expenditure medicine (norepinephrine agonist, β
3-adrenoceptor agonists etc.), suppress to digest and assimilate medicine (like lipase inhibitor etc.).The effect of medicine appetite-suppressing maincenters such as central appetite suppressant such as amfetamine, fluoxetine, Sertraline, sibutramine is stronger; Treatment of obesity has effect preferably, but insomnia, cardiopalmus, headache, gastrointestinal upset, hypertension and nervousness or the like significant side effects is arranged.Take the generation of meeting initiation drug dependence and cardiovascular diseases, diabetes for a long time.Suppress to digest and assimilate medicine orlistat (orlistat) and can cause that gastrointestinal peristalsis is unusual.Short energy expenditure medicine such as gemfibrozil, beclobrate, Lovastatin etc. are the hypolipidemic of certain curative effect, but also with in various degree toxic and side effects.Plant amedica comprises plant extraction class, Chinese herbal medicine class and Chinese medicinal formulae class, and in various degree blood fat reducing and antiobesity action are all arranged, but also with in various degree toxic and side effects.Can know that to sum up the chemical medicine and the Chinese herbal medicine of treatment of obesity have certain side effect and untoward reaction mostly.The bent U.S. slimming capsule that occupies a large amount of domestic markets share of called optical imaging etc. is that the appetrol of main component are suspended sale of with Sibutramine hydrochloride (Sibutramine HCL) in recent years, occurs the situation of fat-reducing medicine imbalance of supply and demand on the market.
Therefore, the Chinese medicine composition, preparation and the food that good effect, safe control are provided and/or reduce fat content (Weight-reducing and lipid-lowering) have vast market demand and important social and economic benefit.
Summary of the invention
In view of this, the present invention provides Chinese medicine composition, preparation and the food of a kind of control and/or minimizing fat content (Weight-reducing and lipid-lowering).The present invention adopts edible natural raw material Fructus Mangifera Indicae, Ganoderma, Fructus Crataegi, Flos Chrysanthemi, Fructus Lycii, can regulate the activity of human body metabolic enzyme, quickens the oxidation Decomposition of body fat tissue, has the overweight people's of improvement health and functions of lowering blood-fat and reducing weight.The present invention's control and/or minimizing fat content (Weight-reducing and lipid-lowering) good effect, persistent are stablized, are had no adverse reaction.Chinese medicine composition provided by the invention, preparation and food are through the studies on acute toxicity evidence, and is without any side effects.
In order to realize the foregoing invention purpose, the present invention provides following technical scheme:
The invention provides a kind of Chinese medicine composition, its raw material by following weight portion is processed:
Fructus Mangifera Indicae contains various nutrients and vitamin C, mineral, in vivo synthetic of the chimonin scalable fatty acid that it is rich in, and the back bounce-back can prevent to lose weight; Ganoderma has effects such as invigorating QI and tranquilization, relieving cough and asthma, blood fat reducing, enhance immunity; The Fructus Crataegi main component is organic acid and flavone compound, has that removing food stagnancyization stagnates, a blood fat reducing, arteriosclerosis effect, can promote the digestion of fat food; Flos Chrysanthemi has that suppressing the hyperactive liver makes eye bright, the effect of heat-clearing and toxic substances removing; Fructus Lycii has the effect of nourishing the liver and kidney, nourishing the liver to improve visual acuity, can blood pressure lowering, blood fat reducing, improve immune function of human body.
The method for preparing of Chinese medicine composition provided by the invention can be decocting, also can be alcohol extraction, and two kinds of methods all can reach identical or close effect.
As preferably, a kind of Chinese medicine composition provided by the invention is processed by the raw material of following weight portion:
The present invention also provides medicine and/or the Application in Food of Chinese medicine composition in preparation control and/or minimizing fat content, and this Chinese medicine composition is processed by the raw material of following weight portion:
The present invention also provides a kind of control and/or has reduced the Chinese medicine preparation of fat content, is made up of Chinese medicine composition and acceptable accessories, and this Chinese medicine composition is processed by the raw material of following weight portion:
As preferably, Chinese medicine preparation provided by the invention is an oral formulations.
As preferably, Chinese medicine preparation provided by the invention is capsule, granule, pill, tablet, decoction, unguentum, distillate medicinal water, oral solutions, drop pill, syrup.
The present invention also provides a kind of control and/or has reduced the method for preparing of the Chinese medicine preparation of fat content, comprises the steps:
Its raw material by following weight portion is formed:
Step 1: get raw materials mix, add ethanol extraction, filtering and collecting filter liquid, concentrate and obtain thick paste;
Step 2: get said thick paste and add acceptable accessories, promptly get.
The method for preparing of Chinese medicine preparation provided by the invention is not limited to said method, and decocte with water also can reach identical or close effect.
As preferably, the relative density of thick paste is 1.10～1.15 (60 ℃) in the step 1.
As preferably, concentration of ethanol is 50～95% in the step 1.
As preferably, be extracted as reflux, extract, 2h in the step 1.
The present invention also provides a kind of control and/or has reduced the method for preparing of the food of fat content, comprises the steps:
Its raw material by following weight portion is formed:
Step 1: get raw materials mix, add ethanol extraction, filtering and collecting filter liquid, concentrate and obtain thick paste;
Step 2: get thick paste and add acceptable additive in the food, promptly get.
As preferably, the relative density of thick paste is 1.10～1.15 (60 ℃) in the step 1.
As preferably, concentration of ethanol is 50～95% in the step 1.
As preferably, be extracted as reflux, extract, 2h in the step 1.
The present invention adopts edible natural raw material Fructus Mangifera Indicae, Ganoderma, Fructus Crataegi, Flos Chrysanthemi, Fructus Lycii etc.; Utilize the effective ingredient that they contain; Can regulate the activity of human body metabolic enzyme, quicken the oxidation Decomposition of body fat tissue, have the overweight people's of improvement health and functions of lowering blood-fat and reducing weight.The present invention's control and/or minimizing fat content good effect, persistent are stablized, are had no adverse reaction.Chinese medicine composition provided by the invention, preparation and food are through the studies on acute toxicity evidence, and is without any side effects.
The specific embodiment
The invention discloses Chinese medicine composition, preparation and the food of a kind of control and/or minimizing fat content (Weight-reducing and lipid-lowering), those skilled in the art can use for reference this paper content, suitably improve technological parameter and realize.Special needs to be pointed out is that all similarly replace and change apparent to those skilled in the art, they all are regarded as and are included in the present invention.Method of the present invention and application are described through preferred embodiment; The related personnel obviously can change or suitably change and combination methods and applications as herein described in not breaking away from content of the present invention, spirit and scope, realizes and use technology of the present invention.
Control provided by the invention and/or reduce in Chinese medicine composition, preparation and the food of fat content (Weight-reducing and lipid-lowering) raw materials used and reagent and all can buy by market.
Below in conjunction with embodiment, further set forth the present invention:
The preparation of embodiment 1 Chinese medicine composition
Get above-mentioned raw materials and mix, add 95% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.12 (60 ℃), promptly gets.
The preparation of embodiment 2 Chinese medicine compositions
Get above-mentioned raw materials and mix, add 50% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.13 (60 ℃), promptly gets.
The preparation of embodiment 3 Chinese medicine compositions
Get above-mentioned raw materials and mix, add 75% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.10 (60 ℃), promptly gets.
The preparation of embodiment 4 Chinese medicine compositions
Get above-mentioned raw materials and mix, add 90% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.15 (60 ℃), promptly gets.
Embodiment 5 Chinese medicine compositions of the present invention are to animal body fat effect of accumulation
With 36 mices, arbitrarily be divided into three groups, the A group is taken high fat high heat feedstuff, and the B group is taken normal diet, and the C group is taken the high fat high heat feedstuff (Chinese medicine composition consumption 8g/Kg) that is added with embodiment 1 to 4 preparation Chinese medicine composition.Survey food-intake every day, survey body weight weekly, 4 weeks of breeding observing, last anatomic observation interior fat, and get ventral aorta blood testing fat and T-CHOL (TC), testing result is seen table 1.
Table 1 is taken the influence of the Chinese medicine composition of embodiment 1 to 4 preparation to mice body weight, body fat and TC
| Group | A | B | C |
| Weightening finish/food-intake | 0.423±0.019 | 0.247±0.037* | 0.219±0.012* |
| Interior fat/weightening finish | 0.039±0.008 | 0.021±0.010* | 0.018±0.007* |
| TC（mmol/L） | 2.56±0.26 | 1.88±0.35* | 1.63±0.27* |
Compare * P < 0.05 with control group A
This experimental result shows that the Chinese medicine composition of taking embodiment 1 to 4 preparation has the obvious control effect to the fatty accumulation of mice, and can hypercholesterolemia reducing content.
The toxicity research test of embodiment 6 Chinese medicine compositions of the present invention
Studies on acute toxicity:
Get Kunming mouse, irritate stomach by 10g/kg and give medicine of the present invention (embodiment 1 to 4 prepared Chinese medicine composition), successive administration was 4 times in 1 day, and each 6h at interval gives normal diet then, and each organ is carried out the pathologic inspection, does not find organ disease.
Long term toxicity research:
Get Kunming mouse; In pressing, (4g/g 8g/kg) irritates stomach and gives medicine of the present invention (embodiment 1 to 4 prepared Chinese medicine composition), every day 1 time heavy dose of group; Behind the successive administration 14 days; Measure indexs such as mice body weight, cardiac function, liver function, renal function, electrocardiogram, the administration group compares with matched group respectively, does not see obviously unusual.Internal organs such as the pathological examination heart, liver,kidney,spleen, lung, stomach, duodenum, large intestine, small intestinal, adrenal gland and genitals, administration group compare with matched group respectively, do not see that all obvious toxic changes.This Chinese medicine composition safety non-toxic of above results suggest can be used for clinical.
Embodiment 7 clinical trials
75 routine obese patients are divided into five groups at random, and average every group 15 example sets up matched group and four treatment groups separately, and different with matched group is the Chinese medicine composition that the treatment group makes at the foregoing description 1 to embodiment 4 that takes night and morning respectively.
Clinical data: be the Simple Obesity patient in 75 examples, the course of disease is the shortest 1 year, and is the longest 30 years.Slight fat 15 examples, fat 40 examples of moderate, fat 20 examples of severe.
The clinical physical data of table 2
Diagnosis and criterion of therapeutical effect:
Diagnostic criteria: according to " practical internal medicine " regulation, 20% [SBW=(height-100) cm * 0.9] of the body weight that is above standard or Body Mass Index are greater than 24.
Fat division and criterion of therapeutical effect: with reference to national combination of Chinese and Western medicine obesity in 1987
The Simple Obesity curative effect judging standard that the research seminar is confirmed.
The slight obesity body weight 20～30% that is above standard
The moderate obesity body weight 30～50% that is above standard
The severe obesity is above standard body weight greater than 50%
Produce effects weight loss >=10kg, waistline minimizing >=10cm
Effective weight loss >=3kg, waistline minimizing >=4cm
Invalid weight loss＜3kg, waistline minimizing＜4cm
Therapeutic Method:
The treatment group prepared Chinese medicine composition of embodiment 1 to 4 that takes night and morning every day is equivalent to crude drug amount 10g, diet, the no specific (special) requirements of motion at every turn.Statistics fat-reducing result after one month, the result sees table 3.
The clinical comparison (%) of respectively organizing curative effect of table 3
| Group | The example number | Produce effects | Effectively | Invalid | Total effective rate |
| Embodiment 1 | 15 | 2 | 10 | 3 | 80 |
| Embodiment 2 | 15 | 2 | 11 | 2 | 87 |
| Embodiment 3 | 15 | 1 | 10 | 4 | 74 |
| Embodiment 4 | 15 | 0 | 11 | 5 | 74 |
| Matched group | 15 | 0 | 0 | 0 | 0 |
Can find out that from table 2 apparently higher than matched group, total effective rate is at least 74% to the treatment group of each embodiment on fat-reducing effect.Explain that Chinese medicine composition provided by the invention has the effect of obvious control and/or minimizing fat content (lowering blood-fat and reducing weight).
The preparation of embodiment 8 tablets
Get above-mentioned raw materials and mix, add 95% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.10 (60 ℃), adds conventional adjuvant again, adopts conventional method to make tablet.
The preparation of embodiment 9 decoctions
Get above-mentioned raw materials and mix, add 50% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.15 (60 ℃), adds conventional adjuvant again, adopts conventional method to make decoction.
The preparation of embodiment 10 unguentum
Get above-mentioned raw materials and mix, add 75% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.13 (60 ℃), adds conventional adjuvant again, adopts conventional method to make unguentum.
The preparation of embodiment 11 distillate medicinal waters
Get above-mentioned raw materials and mix, add 95% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.12 (60 ℃), adds conventional adjuvant again, adopts conventional method to make distillate medicinal water.
The preparation of embodiment 12 capsules
Get Fructus Mangifera Indicae 600g, Ganoderma 200g, Fructus Crataegi 500g, Flos Chrysanthemi 100g, Fructus Lycii 300g, with the above-mentioned raw materials mixing; Add 10 liter of 80% ethanol and carry out reflux, extract, 2 times, each 60min.Filter, it is 1.10 (60 ℃) that filtrate decompression is concentrated into relative density, spray drying; The adjuvant that adds an amount of capsule, mixing is granulated, and the capsule of packing into No. 1 promptly gets.
The preparation of embodiment 13 granules
Get Fructus Mangifera Indicae 500g, Ganoderma 300g, Fructus Crataegi 400g, Flos Chrysanthemi 200g, Fructus Lycii 400g, with the above-mentioned raw materials mixing; Add 10 liter of 80% ethanol and carry out reflux, extract, 2 times, each 60min.Filter, it is 1.12 (60 ℃) that filtrate decompression is concentrated into relative density, spray drying; Add adjuvants such as suitable amount of sucrose, starch, granulate, promptly get.
The preparation of embodiment 14 pills
Get Fructus Mangifera Indicae 300g, Ganoderma 100g, Fructus Crataegi 300g, Flos Chrysanthemi 100g, Fructus Lycii 200g, with the above-mentioned raw materials mixing; Add 6 liter of 80% ethanol and carry out reflux, extract, 2 times, each 60min.Filter, it is 1.11 (60 ℃) that filtrate decompression is concentrated into relative density, spray drying; Add an amount of starch supplementary material, pill promptly gets.
The preparation of embodiment 15 oral solutionses
Get above-mentioned raw materials and mix, add 95% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.12 (60 ℃), adds conventional adjuvant again, adopts conventional method to make oral solutions.
The preparation of embodiment 16 drop pills
Get above-mentioned raw materials and mix, add 95% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.10 (60 ℃), adds conventional adjuvant again, adopts conventional method to make drop pill.
The preparation of embodiment 17 syrups
Get above-mentioned raw materials and mix, add 50% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.15 (60 ℃), adds conventional adjuvant again, adopts conventional method to make syrup.
The preparation of embodiment 18 Weight-reducing and lipid-lowerings sugar
Get above-mentioned raw materials and mix, add 95% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.10 (60 ℃), adds conventional additives again, adopts conventional method to make the Weight-reducing and lipid-lowering confection.
The preparation of embodiment 19 tea for reducing weight and lowering fat
Get above-mentioned raw materials and mix, add 50% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.15 (60 ℃), adds conventional additives again, adopts conventional method to make tea for reducing weight and lowering fat.
The preparation of embodiment 20 Weight-reducing and lipid-lowering beverages
Get above-mentioned raw materials and mix, add 75% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.13 (60 ℃), adds conventional additives again, adopts conventional method to make the Weight-reducing and lipid-lowering beverage.
Embodiment 21 Weight-reducing and lipid-lowering noodle preparation
Get above-mentioned raw materials and mix, add 95% alcohol reflux 2h, filtering and collecting filter liquid, concentrate and obtain thick paste, the relative density of thick paste is 1.12 (60 ℃), adds conventional additives again, adopts conventional method to make the Weight-reducing and lipid-lowering noodles.
The above only is a preferred implementation of the present invention; Should be pointed out that for those skilled in the art, under the prerequisite that does not break away from the principle of the invention; Can also make some improvement and retouching, these improvement and retouching also should be regarded as protection scope of the present invention.
Claims (10)
1. a Chinese medicine composition is characterized in that, its raw material by following weight portion is processed:
2. Chinese medicine composition according to claim 1 is characterized in that, its raw material by following weight portion is processed:
3. Chinese medicine composition according to claim 1 is in the medicine and/or the Application in Food of preparation control and/or minimizing fat content.
4. the Chinese medicine preparation controlling and/or reduce fat content is characterized in that, is made up of Chinese medicine composition according to claim 1 and acceptable accessories.
5. Chinese medicine preparation according to claim 4 is characterized in that, it is an oral formulations.
6. Chinese medicine preparation according to claim 5 is characterized in that, it is capsule, granule, pill, tablet, decoction, unguentum, distillate medicinal water, oral solutions, drop pill, syrup.
7. the method for preparing controlling and/or reduce the Chinese medicine preparation of fat content is characterized in that, comprises the steps:
Its raw material by following weight portion is formed:
Step 1: get said raw materials mix, add ethanol extraction, filtering and collecting filter liquid, concentrate and obtain thick paste;
Step 2: get said thick paste and add acceptable accessories, promptly get.
8. method for preparing according to claim 7 is characterized in that, the relative density of thick paste described in the step 1 is 1.10～1.15 (60 ℃).
9. the method for preparing controlling and/or reduce the food of fat content is characterized in that, comprises the steps:
Its raw material by following weight portion is formed:
Step 1: get said raw materials mix, add ethanol extraction, filtering and collecting filter liquid, concentrate and obtain thick paste;
Step 2: get said thick paste and add acceptable additive in the food, promptly get.
10. method for preparing according to claim 9 is characterized in that, the relative density of thick paste described in the step 1 is 1.10～1.15 (60 ℃).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210259317.8A CN102743504B (en) | 2012-07-25 | 2012-07-25 | Chinese medicinal composition for reducing weight and lowering lipid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210259317.8A CN102743504B (en) | 2012-07-25 | 2012-07-25 | Chinese medicinal composition for reducing weight and lowering lipid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102743504A true CN102743504A (en) | 2012-10-24 |
| CN102743504B CN102743504B (en) | 2014-08-13 |
Family
ID=47024233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210259317.8A Expired - Fee Related CN102743504B (en) | 2012-07-25 | 2012-07-25 | Chinese medicinal composition for reducing weight and lowering lipid |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102743504B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375847A (en) * | 2017-08-14 | 2017-11-24 | 青岛康尔高科实业有限公司 | A kind of slimming medicine, its preparation method and application |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101954005A (en) * | 2009-07-13 | 2011-01-26 | 佰研生化科技股份有限公司 | Herbal composition for osteoarthritis |
| CN102397277A (en) * | 2011-11-17 | 2012-04-04 | 成都欣捷高新技术开发有限公司 | Esomeprazole-containing medicinal composition |
-
2012
- 2012-07-25 CN CN201210259317.8A patent/CN102743504B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101954005A (en) * | 2009-07-13 | 2011-01-26 | 佰研生化科技股份有限公司 | Herbal composition for osteoarthritis |
| CN102397277A (en) * | 2011-11-17 | 2012-04-04 | 成都欣捷高新技术开发有限公司 | Esomeprazole-containing medicinal composition |
Non-Patent Citations (1)
| Title |
|---|
| 编辑: "澳大利亚研究发现芒果皮有助减肥", 《饮料工业》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375847A (en) * | 2017-08-14 | 2017-11-24 | 青岛康尔高科实业有限公司 | A kind of slimming medicine, its preparation method and application |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102743504B (en) | 2014-08-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102145158B (en) | Ginger and clove composition, preparation method of ginger and clove composition and use of ginger and clove composition for preparing toxicity-reducing efficacy-improving medicine in cancer radiotherapy and chemotherapy | |
| CN102215850B (en) | Composition containing fucoxanthin extract | |
| CN103861070B (en) | Health product for preventing angiosclerosis | |
| CN102823857A (en) | Ginseng donkey-hide gelatin healthcare food | |
| CN109820905A (en) | A kind of pharmaceutical composition and its application for treating insomnia | |
| CN102231986B (en) | Use of phytoecdysones in the preparation of a composition for acting on metabolic syndrome | |
| EP2891496B1 (en) | PHARMACEUTICAL COMPOSITION CONTAINING COMPLEX EXTRACT OF CRATAEGI FRUCTUS and CITRI PERICARPIUM AS AN ACTIVE INGREDIENT FOR TREATING OR PREVENTING OBESITY OR LIPID-RELATED METABOLIC DISEASES | |
| CN104388236A (en) | Grape wine as well as preparation method and application thereof | |
| CN102188486B (en) | Pharmaceutical composition for preventing and treating fatty liver and preparation method thereof | |
| CN101711840B (en) | Medicine-food dual-purpose composition suitable for cancerous patients and preparation method thereof | |
| CN108813610A (en) | A kind of saussurea involucrata composition and its application for improving immunity | |
| CN106236927A (en) | A kind of Chinese medicine composition with enhancing immunity and antifatigue effect and preparation method thereof and purposes | |
| CN108420890B (en) | Composition with blood fat reducing effect and preparation method thereof | |
| CN101721403A (en) | Application of fucoxanthin in aspect of losing weight | |
| CN101214319B (en) | Chinese medicine health care products capable of regulating blood fat and preparation thereof | |
| CN102743504B (en) | Chinese medicinal composition for reducing weight and lowering lipid | |
| CN110269251A (en) | Composition for relaxing bowels and promoting defecation and preparation method thereof | |
| CN102132870B (en) | Diet health-care product and preparation method thereof | |
| CN109122856A (en) | A kind of liver-protecting sober-up Chinese medicine composition | |
| CN108815218A (en) | Medical composition and its use | |
| CN101062097B (en) | Compound for improving and treating fatty liver | |
| CN100562325C (en) | A kind of Chinese medicine composition for the treatment of tumor and preparation method thereof | |
| CN109394977B (en) | Traditional Chinese medicine composition with blood fat reducing function and preparation method and application thereof | |
| CN102091313A (en) | Composition of perilla leaf and ginger, preparation method thereof and application thereof in preparing attenuating synergistic medicament in radiotherapy and chemotherapy of cancer | |
| CN105193993B (en) | A kind of Chinese medicine composition with blood fat reducing function and preparation method thereof and purposes |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140813 Termination date: 20150725 |
|
| EXPY | Termination of patent right or utility model |