CN102743499B - Chinese medicinal herb drug for treating soft tissue internal injury blood stasis and cerebral hemorrhage and method for preparing same - Google Patents

Chinese medicinal herb drug for treating soft tissue internal injury blood stasis and cerebral hemorrhage and method for preparing same Download PDF

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CN102743499B
CN102743499B CN201210264058.8A CN201210264058A CN102743499B CN 102743499 B CN102743499 B CN 102743499B CN 201210264058 A CN201210264058 A CN 201210264058A CN 102743499 B CN102743499 B CN 102743499B
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medicine
blood stasis
soft tissue
chinese herbal
internal injury
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CN102743499A (en
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苏庆勤
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Abstract

The invention discloses a Chinese medicine herb drug for treating soft tissue internal injury blood stasis and cerebral hemorrhage and a preparation method of the Chinese medicine herb drug. The Chinese medicine herb drug comprises the following principal herbs by weight: 10-20 parts of Indian abutilon root, 6-15 parts of sappanwood and 10-20 parts of mullein mightbrier leaf. The preparation method comprises the steps as follows: extracting active ingredients of Chinese medicine herbs by water extraction or/and alcohol extraction, and preparing into various oral preparations. The Chinese medicine herb drug is mainly used for treating various pains and blood stasis caused by soft tissue internal injury blood stasis and cerebral hemorrhage, has the characteristics of definite treatment effect, quick action, high healing rate and convenience in taking, and can achieve the aim of radical treatment. The multi-year clinical test proves that the total efficiency is 90.6%. The Chinese medicine herb drug has the advantages of easily available raw materials, low cost, green and environmental protection, low drug dose, low production cost and good economic and social benefits.

Description

Medicine of Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage and preparation method thereof
Technical field
The invention belongs to pharmaceutical technology sectors, relate to a kind of herbal composite, specifically, relate to medicine of a kind of Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage and preparation method thereof.
Background material
Acute soft tissue internal injury blood stasis and cerebral hemorrhage are the commonly encountered diseases of traumatology.Acute soft tissue internal injury blood stasis and the modal symptom of cerebral hemorrhage are pain, swelling, dysfunction.Cerebral hemorrhage is also cerebral hemorrhage, and after referring to rupture of blood vessel in brain, blood flows in brain matter.The patient of about 80% occurs in cerebral hemisphere, and the patient of about 20% occurs in cerebellum and brain stem.The cause of disease of cerebral hemorrhage is a lot, and abrasive once hemorrhage, can cause brain local blood circulation obstacle, causing acute brain internal injury blood stasis symptom, is common mainly with hemiplegia, aphasia, stupor etc.Therapeutic Method has two kinds, and one is operation, and another kind is taken medicine.As patient's intracerebral hemorrhage 40-100CC, usually adopt opening operation cranium, there is medical expense large, sequela is comparatively serious, the problem that mortality rate is higher.Although some patients have kept life, the patient of about 90% there will be Cranial nerve injury as birth trauma in various degree, causes and can't take care of oneself or become plant man.As patient's intracerebral hemorrhage 5-40CC, usually adopt intravenously administrable, the patient of about 30% can cure, and the patient of about 50% cannot cure, and the patient of the about 20% on the contrary state of an illness can increase the weight of, and even cause death, its curative effect is low.In addition, the patient of intracerebral hemorrhage is by taking modern patent medicine or Western medicine etc., and its medicine time is long, and sb.'s illness took a favorable turn slowly, and cure rate generally only has 10-20%, and its curative effect is low equally.
The internal injury blood stasis that soft tissue internal injury blood stasis and muscle internal injury blood stasis refer to human body skin or subcutaneous tissue, muscle, joint grain are clashed into suddenly and the reason such as compressing causes; Be commonly called as 100 days injured in the sinews or bones, this disease recovery is slow in other words.At present, in the treatment that market is sold, the medicine of wound is many, each has something to recommend him, and great majority have certain curative effect.Existing Therapeutic Method mainly Dressed plaster, or put on the skin outside medicinal liquid, or Chinese traditional medicine wet compress and smoked etc., but can rapid pain relief, cure as early as possible little, seriously have impact on the live and work of patient.
Motherland's medical science is thought, pain is because human body muscle arteries and veins is impaired, and qi and blood circulation is smooth and caused by stagnating; Swelling is owing to damaging the retardance of rear scabies blood, caused by QI and blood is obstructed; If deficient qi and blood, be affected by the cold damp, forms the numbness resistance of network road, make meridians contraction anxious, do to swell and have a pain, can cause joint joint stuffiness.Modern medicine is thought, after damage the microstructure damage of local organization cell and microtubule break, hemorrhage, and histiocyte congestion and edema and degeneration necrosis cause impaired local swelling, pain, simultaneously, local organization cell discharges inflammatory mediator, metabolite is assembled and is caused environment to change, and causes damaging cells dysbolismus, thus increases the weight of local symptom and sign and pathological change.In treatment, modern medicine then often adopts anti-inflammatory analgesic class Drug therapy; The traditional Chinese medical science advocates invigorating blood circulation scabies method, and mostly external used medicine is the medicine being applied to injury local, also has for oral administration and external medication, in treating trauma, occupies critical role, and the traditional Chinese medical science and treatment by Chinese herbs are the characteristics of Chinese cerebral hemorrhage and the treatment of soft tissue internal injury blood stasis.The starting point in diagnosis had both seen that expectorant scabies impatency brain network or brain network are damaged, domination of pathogen sign outside blood oozing from the body openings or subcuta neous tissue arteries and veins, paid attention to again the syndrome of yin and yang qi and blood disorder.Therapeutic Principle is treating both the principal and secondary aspects of a disease, and Comprehensive Treatment is integrally-regulated, treats method for the treatment of with heat-clearing and toxic substances removing, invigorating blood circulation scabies, the purging FU-organs that reduces phlegm, consciousness and resuscitation restoring, suppressing the hyperactive liver and subsiding YANG, the methods such as diuretic of reducing phlegm for clinical syndrome differentiation.
Chinese patent CN20081005025608, a kind for the treatment of of the dredging stagnation of QI blood stasis soft tissue, muscle injury medicine; Be made up of following weight parts crude drug: Corium elephatis 15-25, Fructus Cnidii 8-12, Lignum Aquilariae Resinatum 14-25, Rhizoma Dioscoreae 8-12, Radix Achyranthis Bidentatae 8-12, Plumula Nelumbinis 3-7, volt 03-7, injustice SIZI 8-12, Radix Ginseng Rubra 8-12, Flos Caryophylli 8-12, Radix Aucklandiae 8-12, Radix Salviae Miltiorrhizae 8-12, Radix Angelicae Sinensis 8-12, Herba Cistanches 8-12, Rhizoma Cyperi 3-7, Radix Notoginseng 14-20, Massa Medicata Fermentata 3-7, Radix Glycyrrhizae 3-7, Borneolum Syntheticum 3-7, Moschus 0.1-0.2; Its preparation method is: taken by said medicine formula, pulverizes, and is smalls altogether.Cure mainly and be: internal injury, damaged lung, bone damage, skin and flesh cancerous protuberance, the injury of tendon and muscle, muscle swell, muscle is poly-, muscle knob, version of tendon and muscle, muscle dodge, muscle is twisted, the various pain of soft tissue; There is medication few, cheap, make simple, do not have toxic and side effects, fire-toxin not to injure internal organs, remove the stagnation of QI, leukemia, do not stay the advantage of sequela and determined curative effect.
Chinese patent CN20061003701301, the medicine for the treatment of cerebral hemorrhage, the raw material primarily of following weight parts is made: ground steady root 8-l2 part, Herba Pileae Scriptae l0-20 part, Radix Acanthopanacis Trifoliati l0-l5 part, Radix Cirsii Japonici 6-20 part, Radix Salviae Miltiorrhizae 15-25 part, Radix Ilicis Pubescentis l0-20 part, Ramulus Mori 20-30 part, Herba Leonuri l0-l5 part, Fructus Ligustri Lucidi 12-20 part, Radix Achyranthis Bidentatae l0-20 part, stone battalion Pu l0-l5 part.We have the merit of hematocele, vessel softening, dredge the meridian passage, consciousness and resuscitation restoring, good in strengthening stomach and tonifying kidney in cooling blood for hemostasis, rapid crazy brain.No matter patient's brain inner product blood volume is how many, and when brainpan is opened at end, patient is in 2-20 days, as long as stable disease, even plant man, slotting stomach gavages and can swallow and flows juice medicinal liquid, and take medicine of the present invention, curative effect is best, and effective percentage reaches 96.5%.
Chinese patent CN20lll0273420.3, for a powder for dispersing blood stasis for soft tissue injury and cervical spondylosis, be mainly made up of the crude drug of following weight portion: Herba Taraxaci 1150-1350 part, Radix Et Rhizoma Rhei 400-600 part, Myrrha 400-600 part, Radix Notoginseng 400-600 part, Eupolyphaga Seu Steleophaga 400-600 part, geranium 725-925 part.Have that significant dissipating blood stasis stimulates the menstrual flow, the effect of pain relieving eliminating impediment.Be applicable to the pain caused by cervical spondylosis, osteoarthritis, lumbar muscle strain, prolapse of lumbar intervertebral disc, rheumatic arthritis, hyperosteogeny, gout, scapulohumeral periarthritis, swelling, inflammation; And fall the disease that spit of fland is damaged, hematocele becomes the stasis of blood, long-pending block is loose, the joint stasis of blood is stagnant.Toxic and side effects is little, has less flavour of a drug number and good curative effect, is suitable for life-time service, is one medicine safely and effectively.
Summary of the invention
Object of the present invention: be to soft tissue internal injury blood stasis and cerebral hemorrhage can reach determined curative effect, effective fast, price is low and provide medicine of a kind of Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage and preparation method thereof.
The present invention is achieved in that
A medicine for Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage, main former medicine component and proportioning parts by weight: Radix abutili indici 10-20 part, Lignum Sappan 6-15 part and mullein mightbrier leaf 10-20 part.
The medicine of above-described Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage, described former medicine component and proportioning parts by weight are: Radix abutili indici 16-18 part, Lignum Sappan 8-10 part and mullein mightbrier leaf 15-16 part.
The preparation method of the medicine of above-described Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage, with water extraction or/and alcohol extracting method extracts effective component of Chinese herbal medicine, is prepared into oral liquid, tablet, granule, capsule and powder.
The preparation method of above-described oral liquid comprises: raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, 8-12 water is doubly added by the total number raw material of formulation weight, control temperature 75-90 DEG C boils 1-2 hour, filters, and filtering residue again adds 6-8 water doubly and boils 1-2 hour again at temperature 75-90 DEG C, filter, merge extractive liquid, being evaporated to relative density at temperature 60-78 DEG C is 1.05-1.10, prepares burden according to a conventional method, bottling, mounted box and vanning obtain oral liquid product; Or concentrating under reduced pressure is obtained the clear paste that relative density is 1.15-1.25, add Chinese herbal medicine 10-20 pure water dilution doubly, prepare burden according to a conventional method, sterilization, bottling, mounted box and vanning obtain oral liquid product.
The preparation method of above-described powder or capsule comprises: raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, adds 8-12 water doubly, boil 1-2.5 hour, filter to obtain water cooking liquid at temperature 75-90 DEG C by the total number raw material of formulation weight; Filtering residue adds total raw material 5-10 55-70% ethanol water doubly again, and at temperature 50-60 DEG C of alcohol extraction 1-2 hour, filter, it is 1.05-1.15 extractum that the alcohol extract 50-60 DEG C concentrating under reduced pressure obtained obtains relative density; Added by extractum in water cooking liquid, obtain the clear paste that relative density is 1.15-1.25, hot air drying at 60-85 DEG C of concentrating under reduced pressure, pulverize, add adjuvant mixing, sieve, subpackage, mounted box and vanning obtain powder or capsule product; Or raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, hot air drying, pulverize, sieve, subpackage, mounted box and vanning obtain powder or capsule product.
Above-described powder or capsule product add adjuvant mix homogeneously according to a conventional method, sieve, pelletize or film-making, hot air drying, and subpackage and outer package obtain granule or tablet.
Medicine of the present invention takes orally, adult's body weight more than 50 kilograms persons, and take 3 day, each 4-5 grain or sheet, powder is a bag, takes after mixing it with water with yellow wine or warm water:
The function of medicine of the present invention: relaxing muscles and tendons, invigorate blood circulation, circulation of qi promoting, analgesia and repercussive.
Medicine of the present invention cures mainly: the various pain blood stasis of internal injury cerebral hemorrhage and soft tissue internal injury.
The points for attention of medicine of the present invention: patient please uses under physician guidance, contraindication in pregnancy.
Effect of Chinese herb medicine of the present invention and pharmacology thereof illustrate:
Radix abutili indici: Radix abutili indici (Abutilon indicum (L.) Sweet), calls as mill grass roots and the young shield head of cap.Main product in Yunnan, Guangxi, Fujian; Be distributed in the ground such as Fujian, Taiwan, Guangdong, Hainan, Guangxi, Guizhou, Yunnan.
Meridian distribution of property and flavor: sweet in the mouth, property is put down, nontoxic; Enter spleen, lung, urinary bladder channel.
Effect: clearing away heat-damp and promoting diuresis, sensiblely invigorates blood circulation; Cure mainly xeropulmonary cough, stomachache, stomachache, has loose bowels, stranguria, hernia, traumatic injury, Hiccough and deaf.
Lignum Sappan; The heartwood that Lignum Sappan (Caesalpinia sapptanL.) is leguminous plant Lignum Sappan.Another name is Soviet Union's a tree, used in making timber for boats, the Soviet side, lignum sappan, palm fibre wood, Ramulus et Folium Bischofiae Javanicae, red bavin, LIGNUM SAPPAN and the Wen Shu that falls; Be distributed in Yunnan Valley of Jinsha River and river valley, Red River.There is cultivation on the ground such as Fujian, Taiwan, Guangdong, Hainan, Guangxi, Sichuan, Guizhou and Yunnan.
Meridian distribution of property and flavor: sweet in the mouth, salty, property is put down, nontoxic; Enter the heart, liver, harmonization of the stomach large intestine channel.
Effect: function has class Flos Carthami, few with then can and blood, multiplex then can removing blood stasis; Blood circulation promoting and blood stasis dispelling, subduing swelling and relieving pain; Cure mainly married woman's amenorrhea due to stagnation of blood, dysmenorrhea, postpartum stagnation cardiac and abdominal pain, puerperal blood faints, carbuncle, traumatic injury, tetanus.
Mullein mightbrier leaf: mullein mightbrier leaf (Solanum verbascifolium), calls as king's leaf, Radix Et Rhizoma Rhei leaf, mullein mightbrier leaf, stone cigarette, smelly cigarette, Folium solani verbascifolii, warm blade root, Mao Yeshu, native eggplant and husband's palpus.Be distributed in the ground such as Fujian, Taiwan, Guangdong, Hainan, Hong Kong, Guangxi and Yunnan.
Meridian distribution of property and flavor: acrid in the mouth, property is put down.
Function cures mainly: detumescence, removing toxic substances; Cure mainly general edema with yellowish skin, gout, metrorrhagia, treating swelling and pain by traumatic injury, toothache, scrofula, carbuncle skin ulcer, eczema, dermatitis.
The advantage of medicine of the present invention and good effect:
1, medicine of the present invention is the ancient secret recipe of succession, to the various pain blood stasis of internal injury cerebral hemorrhage and soft tissue internal injury, can reach determined curative effect, effective fast, cure rate is high and the feature of taking convenience, patient is got well, reaches the object of radical cure.Clinical through for many years, medication is few, Be very effective.In clinical totally 76 example tests, total effective rate is 90.6%.
2, the prescription of medicine of the present invention is unique, and raw material easily obtains, with low cost, environmental protection, have compared with economic benefit and social benefit.
Detailed description of the invention
One, embodiment is prepared
Embodiment 1: the preparation of oral liquid
1, former medicine component and proportioning weight:
Radix abutili indici 1.7 kilograms, Lignum Sappan 0.8 kilogram and mullein mightbrier leaf 1.6 kilograms.
2, preparation method:
Raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, adds in saucepan, then add the water of former medicine weight sum 10 times, under temperature 95 DEG C of conditions, boil 1.5 hours, filter; Filtering residue adds the water of former medicine weight sum 7 times again, under temperature 95 DEG C of conditions, boil 1 hour again, filters, and merge and boil liquid, being evaporated to relative density at temperature 70 C is 1.10, prepares burden according to a conventional method, and bottling, mounted box and vanning obtain oral liquid product.
Embodiment 2: the preparation of powder
1, former medicine component and proportioning weight:
Radix abutili indici 1.2 kilograms, Lignum Sappan 1.0 kilograms and mullein mightbrier leaf 1.8 kilograms.
2, preparation method
Raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, washing, is less than 11% at temperature 90 DEG C of hot air dryings to moisture content respectively, and pulverize with morcelling machine, mixing, crosses 120 mesh sieves, subpackage 5 grams/bag, and pack, mounted box and vanning obtain powder product.
Embodiment 3: the preparation of capsule
1, former medicine component and proportioning weight:
Radix abutili indici 1.9 kilograms, Lignum Sappan 1.2 kilograms and mullein mightbrier leaf 1.4 kilograms.
2, preparation method
Raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, washing, is less than 11% at temperature 85 DEG C of hot air dryings to moisture content respectively, and pulverize with morcelling machine, mixing, crosses 160 mesh sieves, divides encapsulated, and bottling, mounted box and vanning obtain capsule product.
Embodiment 4: the preparation of granule
1, former medicine component and proportioning weight:
Radix abutili indici 1.1 kilograms, Lignum Sappan 1.1 kilograms and mullein mightbrier leaf 1.7 kilograms.
2, preparation method
Raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, adds the water of former medicine weight sum 8 times, boil 2.0 hours temperature 86 DEG C, filter to obtain water cooking liquid; Filtering residue adds 60% ethanol water of raw material 8 times again, and temperature 50 C alcohol extraction 1.5 hours, filter, it was 1.10 extractum that the alcohol extract obtained obtains relative density with 65 DEG C of temperature concentrating under reduced pressure; Added by extractum in water cooking liquid, obtain the clear paste that relative density is 1.20, hot air drying at temperature 70 C concentrating under reduced pressure, pulverize, add adjuvant mixing, after sieving, pelletize according to a conventional method, hot air drying, sieves, and subpackage and outer package obtain granule product.
Embodiment 5: the preparation of tablet
1, former medicine component and proportioning weight:
Radix abutili indici 1.6 kilograms, Lignum Sappan 0.9 kilogram and mullein mightbrier leaf 1.5 kilograms.
2, preparation method
Raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, adds the water of former medicine weight sum 10 times, boil 1.5 hours temperature 80 DEG C, filter to obtain water cooking liquid; Filtering residue adds 65% ethanol water of raw material 10 times again, and temperature 60 C alcohol extraction 1.0 hours, filter, it was 1.15 extractum that the alcohol extract obtained obtains relative density with 60 DEG C of temperature concentrating under reduced pressure; Added by extractum in water cooking liquid, obtain the clear paste that relative density is 1.15, hot air drying at 85 DEG C of temperature concentrating under reduced pressure, pulverize, add adjuvant mixing, cross 160 mesh sieves, according to a conventional method film-making, hot air drying, sieves, and subpackage and outer package obtain tablet.
Two, clinical drug trial
Clinical data:
Select internal injury cerebral hemorrhage and soft tissue internal injury blood stasis patient 76 example in the rear 48h of morbidity, major part is subject to the internal injuries such as outside striking head, thorax abdomen and extremity, without stupor, liver,spleen,kidney is without pathological changes, have part to carry out CT examination to confirm, 18 ~ 78 years old age, average 46.1 years old, amount of bleeding 12 ~ 60CC, average 28.5CC.
Therapeutic Method:
Adopt the present invention to prepare the oral liquid of embodiment, tablet, granule, capsule and powder, day for oral administration takes 3 times.Divide with 15d, 30d and 60d treatment respectively, after terminating the course for the treatment of, CT observes blood stasis absorbing state, and total effective rate is 90.6%.
Conclusion:
For many years. Chinese herbal treatment internal injury cerebral hemorrhage of the present invention on probation and soft tissue internal injury blood stasis medicine, application for the treatment of internal injury patients with cerebral hemorrhage 26 example and soft tissue internal injury patient 50 example, from therapeutic outcome, Radix abutili indici of the present invention, Lignum Sappan, mullein mightbrier leaf are the medicine of vessel softening, dredge the meridian passage and blood circulation promoting and blood stasis dispelling, energy vessel softening, dredge the meridian passage and blood circulation promoting and blood stasis dispelling, absorption of hematoma is very fast, pain relieving and improve the effect of erythrocyte deformability, be conducive to improving microcirculation, promote that internal injury cerebral hemorrhage and soft tissue internal injury are cured.
Application test example
Embodiment 1
Chen, male, 46 years old, on June 3rd, 2008 got into an accident, chest soft tissue internal injury, pain blood stasis, and local is purple obviously black, and within 12 days, have no improvement with conventional treatment by Chinese herbs, the pain increased on the contrary.June 16 rose and takes powder product of the present invention, three times on the one for oral administration, and each bag, occurs after 3 days taking a turn for the better, reduce pain, and swollen rising also starts abatement.Take 10 days pain more continuously substantially to eliminate, 15 days entirely more.
Embodiment 2
Multitude, women, 53 years old, on October 21st, 20011 causes damaging cerebral hemorrhage because of the brain internal injury that slips, and during intracerebral hemorrhage 21CC, causes brain local blood circulation obstacle, cause acute cerebral insult symptom, aphasia, adopt intravenously administrable doctor, treat two months sick without improvement.Take oral solutions product of the present invention, three times on the one for oral administration, each bag, occurs after taking the 8th day taking a turn for the better, can sound, and within the 22nd day, recovers linguistic competence.Take continuously through x-ray inspection after two months, cerebral hemorrhage is eliminated again.
Embodiment 3
Huang, male, 35 years old, on May 5th, 2006 caused brain and internal injury of chest because fighting, and causes cerebral haemorrhage, intracerebral hemorrhage 60CC, causes chest pain, inside and outside blood stasis simultaneously.Cause brain local blood circulation obstacle, cause acute cerebral insult, aphasia symptom, brain pain.Take granule product of the present invention, three times on the one for oral administration, each bag.After taking the 3rd day, chest pain takes a turn for the better; Can sound after 10th day, internal injury of chest pain is almost recovered; Linguistic competence is recovered after 16th day; After taking two months continuously, through x-ray inspection, cerebral haemorrhage is eliminated, and symptomatology is fully recovered.
Embodiment 4
Deep so-and-so, women, 22 years old, on March 16th, 2010 caused leg and waist internal injury pain, inside and outside blood stasis because of traffic accident.Cause disturbance of blood circulation.Take capsule product of the present invention two days later, three times on the one for oral administration, each 5.After taking the 4th day, affected part pain takes a turn for the better; After taking the 12nd day, affected part pain is eliminated; After taking one month continuously, through x-ray inspection, symptomatology is fully recovered.

Claims (6)

1. a medicine for Chinese herbal treatment soft tissue internal injury blood stasis and cerebral hemorrhage, is characterized in that: be made up of following component and proportioning parts by weight: Radix abutili indici 10-20 part, Lignum Sappan 6-15 part and mullein mightbrier leaf 10-20 part.
2. the medicine of Chinese herbal treatment soft tissue internal injury blood stasis according to claim 1 and cerebral hemorrhage, is characterized in that: described former medicine component and proportioning parts by weight are: Radix abutili indici 16-18 part, Lignum Sappan 8-10 part and mullein mightbrier leaf 15-16 part.
3. the preparation method of the medicine of Chinese herbal treatment soft tissue internal injury blood stasis according to claim 1 and 2 and cerebral hemorrhage, it is characterized in that: extract effective component of Chinese herbal medicine with water extraction+alcohol extracting method, be prepared into oral liquid, tablet, granule, capsule and powder.
4. the preparation method of the medicine of Chinese herbal treatment soft tissue internal injury blood stasis according to claim 3 and cerebral hemorrhage, it is characterized in that: the preparation method of described oral liquid comprises: by raw material Chinese herbal medicine Radix abutili indici 10-20 part, Lignum Sappan 6-15 part and mullein mightbrier leaf 10-20 part are screened respectively, 8-12 water is doubly added by the total number raw material of formulation weight, control temperature 75-90 DEG C boils 1-2 hour, filter, filtering residue again adds 6-8 water doubly and boils 1-2 hour again at temperature 75-90 DEG C, filter, merge extractive liquid, being evaporated to relative density at temperature 60-78 DEG C is 1.05-1.10, prepare burden according to a conventional method, bottling, mounted box and vanning obtain oral liquid product, or concentrating under reduced pressure is obtained the clear paste that relative density is 1.15-1.25, add Chinese herbal medicine 10-20 pure water dilution doubly, prepare burden according to a conventional method, sterilization, bottling, mounted box and vanning obtain oral liquid product.
5. the preparation method of the medicine of Chinese herbal treatment soft tissue internal injury blood stasis according to claim 3 and cerebral hemorrhage, it is characterized in that: described powder or the preparation method of capsule comprise: raw material Chinese herbal medicine Radix abutili indici 10-20 part, Lignum Sappan 6-15 part and mullein mightbrier leaf 10-20 part are screened respectively, 8-12 water is doubly added by the total number raw material of formulation weight, boil 1-2.5 hour at temperature 75-90 DEG C, filter to obtain water cooking liquid; Filtering residue adds total raw material 5-10 55-70% ethanol water doubly again, and at temperature 50-60 DEG C of alcohol extraction 1-2 hour, filter, it is 1.05-1.15 extractum that the alcohol extract 50-60 DEG C concentrating under reduced pressure obtained obtains relative density; Added by extractum in water cooking liquid, obtain the clear paste that relative density is 1.15-1.25, hot air drying at 60-85 DEG C of concentrating under reduced pressure, pulverize, add adjuvant mixing, sieve, subpackage, mounted box and vanning obtain powder or capsule product; Or raw material Chinese herbal medicine Radix abutili indici, Lignum Sappan and mullein mightbrier leaf are screened respectively, hot air drying, pulverize, sieve, subpackage, mounted box and vanning obtain powder or capsule product.
6. the preparation method of the medicine of Chinese herbal treatment soft tissue internal injury blood stasis according to claim 5 and cerebral hemorrhage; it is characterized in that: described powder adds adjuvant mix homogeneously according to a conventional method, sieves, pelletize or film-making; hot air drying, subpackage and outer package obtain granule or tablet.
CN201210264058.8A 2012-07-29 2012-07-29 Chinese medicinal herb drug for treating soft tissue internal injury blood stasis and cerebral hemorrhage and method for preparing same Expired - Fee Related CN102743499B (en)

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