Summary of the invention
The present invention relates to a kind of external cream of alleviating paronychia pain, raw material composition and the weight portion of processing this Chinese medicine unguentum are: Radix Salviae Miltiorrhizae 20-45 part, YUNNAN BAIYAO 20-45 part, Rhizoma Coptidis 6-20 part, Radix Et Rhizoma Rhei 10-20 part, Borneolum Syntheticum 15-30 part, Eupolyphaga Seu Steleophaga 20-40 part, Radix Sophorae Flavescentis 20-40 part, Olibanum 20-40 part, posaconazole 1-4 part, terbinafine HCl 1-4 part, nanometer silver 2-8 part, vaseline 500-1000 part.
The present invention is a kind of desirable external cream of alleviating paronychia pain.
Concrete method for preparing of the present invention is:
" Radix Salviae Miltiorrhizae 20-45 part, YUNNAN BAIYAO 20-45 part, Rhizoma Coptidis 6-20 part, Radix Et Rhizoma Rhei 10-20 part, Borneolum Syntheticum 15-30 part, Eupolyphaga Seu Steleophaga 20-40 part, Radix Sophorae Flavescentis 20-40 part, Olibanum 20-40 part "; After the mixing, steeped 5-10 days, filter with 95% an amount of ethanol merceration; Obtain filtrating; Vacuum drying is pulverized, and it is subsequent use to obtain powder;
" posaconazole 1-4 part, terbinafine HCl 1-4 part " with 95% an amount of dissolve with ethanol, it is subsequent use to obtain liquid;
Get " subsequent use powder ", " subsequent use liquid ", mix, obtain unguentum of the present invention with " nanometer silver 2-8 part ", " vaseline 500-1000 part ".
The present invention has detumescence, pain relieving, evacuation of pus, the curative effect of removing the necrotic tissue, granulation promoting.The pain relieving effective percentage is 97%,, be a kind of desirable externally used paste of alleviating paronychia pain.
Embodiment 1
Plaster of the present invention is the feedstock production of following weight fraction (gram):
" 20 parts of Radix Salviae Miltiorrhizaes, 20 parts of YUNNAN BAIYAOs, 6 parts of Rhizoma Coptidis, 10 parts of Radix Et Rhizoma Rhei, 15 parts of Borneolum Syntheticums, 20 parts of Eupolyphaga Seu Steleophagas, 20 parts of Radix Sophorae Flavescentiss, 20 parts of Olibanums " after the mixing, steeped 5 days with 1000 parts 95% ethanol mercerations; Filter, obtain filtrating, vacuum drying; Pulverize, it is subsequent use to obtain powder;
" 1 part of posaconazole, 1 part of terbinafine HCl " with 95% an amount of dissolve with ethanol, it is subsequent use to obtain liquid;
Get " subsequent use powder ", " subsequent use liquid ", mix, obtain unguentum of the present invention with " 2 parts of nanometer silvers ", " vaseline 500 ".
Embodiment 2
Plaster of the present invention is the feedstock production of following weight fraction (gram):
" 45 parts of Radix Salviae Miltiorrhizaes, 45 parts of YUNNAN BAIYAOs, 20 parts of Rhizoma Coptidis, 20 parts of Radix Et Rhizoma Rhei, 30 parts of Borneolum Syntheticums, 40 parts of Eupolyphaga Seu Steleophagas, 40 parts of Radix Sophorae Flavescentiss, 40 parts of Olibanums " after the mixing, steeped 10 days with 2000 parts 95% ethanol mercerations; Filter, obtain filtrating, vacuum drying; Pulverize, it is subsequent use to obtain powder;
" 4 parts of posaconazoles, 4 parts of terbinafine HCls " with 95% an amount of dissolve with ethanol, it is subsequent use to obtain liquid;
Get " subsequent use powder ", " subsequent use liquid ", mix, obtain unguentum of the present invention with " 8 parts of nanometer silvers ", " 1000 parts in vaseline ".
Embodiment 3
The unguentum of the embodiment of the invention 2 adopts 3 grams evenly to spread upon respectively on the skin of 6 white rabbit ears, and is nontoxic, do not have irritated reaction.
Usage and dosage of the present invention: apply 2 time at fingernail and on every side every day, each 0.2 gram, and 15 days is a course of treatment.
The present invention observes case 40 examples, is the paronychia patient.
The unguentum of the embodiment of the invention 2: 20 examples,
Matched group: daktarin: 20 examples, apply 2 time at fingernail and on every side every day, each 0.2 gram, 15 days is a course of treatment,
Pain disappearance (total number of persons, natural law) |
2 days |
4 days |
8 days |
12 days |
15 days |
The unguentum of the embodiment of the invention 2 |
8 people |
10 people |
15 people |
18 people |
19 people |
Matched group |
2 people |
5 people |
6 people |
7 people |
8 people |
The result finds that the unguentum effect of the embodiment of the invention 2 is obvious.