CN104771475A - Traditional Chinese medicine ointment for treating paronychia and preparation method of traditional Chinese medicine ointment - Google Patents
Traditional Chinese medicine ointment for treating paronychia and preparation method of traditional Chinese medicine ointment Download PDFInfo
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Abstract
The invention belongs to the field of traditional Chinese medicines and discloses a traditional Chinese medicine ointment for treating paronychia. The traditional Chinese medicine ointment comprises 5-13 parts of cortex phellodendri n-hexane extracts, 3-8 parts of radix sophorae flavescentis extracts, 6-13 parts of sowthistle tasselflower herb ethanol extracts, 2-6 parts of cocklebur fruit water extracts, 3-7 parts of trumpet creeper water extracts, 5-9 parts of glycerin, 4-10 parts of lauryl alcohol polyoxyethylene and 3-6 parts of starch. The preparation method comprises the steps of extracting; stirring; separating; concentrating; and mixing to prepare the traditional Chinese medicine ointment for treating paronychia. The prepared traditional Chinese medicine ointment has a relatively-high cure rate on the aspect of treating paronychia.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicinal ointment and preparation method thereof, particularly relate to one and treat paronychial Chinese medicinal ointment and preparation method thereof.
Background technology
Paronychial Symptoms: often first occur in side nail groove subcutaneous, show as Ipsilateral red swelling of the skin, pain is general many without systemic infection symptom.If pathological development, intralesional becomes pus, have fluctuation, occur white point, but not easily ulceration comes to a head in red and swollen district.Inflammation also can betide nail root place or expand to opposite side nail groove, and infecting to have that the pain increased and General Symptoms such as heating grade when increasing the weight of.Because fingernail hinders purulence thing to discharge, infection can spread to deep layer and form dactylitis.Paronychia is divided into acute paronychia and chronic paronychia.Treatment paronychia, to inflammation comparatively the lighter, can partial hot compressing, physical therapy or external application YUSHIZHI RUANGAO, be coated with a little erythromycin or the antimicrobial ointment such as ketoconazole, daktarin after iodine disinfection, then wrap up with sterile gauze; If existing pus person, need do the evacuation of pus of stringer otch, the drug of topical application along nail groove on pus.The Chinese medicines such as Rhizoma Curcumae Longae, Radix Et Rhizoma Rhei, Cortex Phellodendri, Fructus Cnidii, Rhizoma Atractylodis, Cortex Magnoliae Officinalis, Arisaema Cum Bile, the Radix Angelicae Dahuricae, Radix Trichosanthis have certain therapeutic efficiency in treatment paronychia.License notification number is that the patent of invention of CN 102743454 discloses one and treats paronychial plaster.It comprises Radix Salviae Miltiorrhizae 45 parts, YUNNAN BAIYAO 45 parts, Rhizoma Coptidis 20 parts, Radix Et Rhizoma Rhei 20 parts, Borneolum Syntheticum 30 parts, Eupolyphaga Seu Steleophaga 40 parts, Radix Sophorae Flavescentis 40 parts, Olibanum 40 parts.This plaster has good curative effect in treatment paronychia.Can be used for effectively treating paronychia.
Summary of the invention
The technical problem solved: the conventional paronychial unguentum for the treatment of has antibiotic unguentum as daktarin unguentum etc., the paronychial unguentum for the treatment of by Chinese herbs is comparatively rare, the object of this invention is to provide the Chinese medicinal ointment that the paronychial Chinese medicine extract of a kind of novel treatment is prepared from.
Technical scheme: the invention discloses one and treat paronychial Chinese medicinal ointment and preparation method thereof, the paronychial Chinese medicinal ointment of described treatment comprises the composition of following weight parts:
Cortex Phellodendri n-hexane extract 5-13 part,
Radix Sophorae Flavescentis ethanol extraction 3-8 part,
Oxtail knee joint ethanol extraction 6-13 part,
Fructus Xanthii water extract 2-6 part,
Flos Campsis water extract 3-7 part,
Glycerol 5-9 part,
Brij30 4-10 part,
Starch 3-6 part.
Further, described one treats paronychial Chinese medicinal ointment, comprises the composition of following weight parts:
Cortex Phellodendri n-hexane extract 7-10 part,
Radix Sophorae Flavescentis ethanol extraction 4-7 part,
Oxtail knee joint ethanol extraction 8-11 part,
Fructus Xanthii water extract 3-5 part,
Flos Campsis water extract 4-6 part,
Glycerol 6-8 part,
Brij30 6-9 part,
Starch 4-5 part.
Further, described one treats paronychial Chinese medicinal ointment, comprises the composition of following weight parts:
Cortex Phellodendri n-hexane extract 8 parts,
Radix Sophorae Flavescentis ethanol extraction 6 parts,
Oxtail knee joint ethanol extraction 9 parts,
Fructus Xanthii water extract 4 parts,
Flos Campsis water extract 5 parts,
Glycerol 7 parts,
Brij30 8 parts,
Starch 5 parts.
Described a kind of preparation method for the treatment of paronychial Chinese medicinal ointment, comprises the steps:
(1) after being pulverized by Cortex Phellodendri, with normal hexane, stirring and leaching is carried out to Cortex Phellodendri, leave standstill after lixiviate, get the supernatant, prepare Cortex Phellodendri n-hexane extract by after supernatant vacuum concentration;
(2) Radix Sophorae Flavescentis and oxtail knee joint is dry, crushed after being dried, carry out agitating heating lixiviate adding dehydrated alcohol, centrifugalize after lixiviate, gets supernatant, will prepare Radix Sophorae Flavescentis ethanol extraction and oxtail knee joint ethanol extraction after supernatant concentration;
(3) respectively by Fructus Xanthii and Flos Campsis lyophilization, mechanical activation comminution after lyophilization, adds hot water stirs's lixiviate after pulverizing, centrifugal after lixiviate, after going precipitation, is concentrated by clear liquid vacuum film, concentrates and obtains Fructus Xanthii water extract and Flos Campsis water extract;
(4) Cortex Phellodendri n-hexane extract 5-13 part, Radix Sophorae Flavescentis ethanol extraction 3-8 part, oxtail knee joint ethanol extraction 6-13 part, Fructus Xanthii water extract 2-6 part, Flos Campsis water extract 3-7 part, glycerol 5-9 part, Brij30 4-10 part, starch 3-6 part is got respectively by weight, by above-mentioned various composition mix homogeneously, be prepared as the paronychial Chinese medicinal ointment for the treatment of.
Described a kind of preparation method for the treatment of paronychial Chinese medicinal ointment, in step (1), during normal hexane lixiviate, feed liquid weight ratio is 1:7, and Extracting temperature is 35 DEG C, and extraction time is 3h, and speed of agitator is 150rpm.
Described a kind of preparation method for the treatment of paronychial Chinese medicinal ointment, be 1:5 to feed liquid weight ratio when Radix Sophorae Flavescentis and the lixiviate of oxtail knee joint in step (2), Extracting temperature is 55 DEG C, and extraction time is 2h.
Described a kind of preparation method for the treatment of paronychial Chinese medicinal ointment, be 1:6 to feed liquid weight ratio when Fructus Xanthii and Flos Campsis lixiviate in step (3), Extracting temperature is 60 DEG C, and extraction time is 5h.
Described a kind of preparation method for the treatment of paronychial Chinese medicinal ointment, in step (3), sublimation drying is 10h-20h.
Described a kind of preparation method for the treatment of paronychial Chinese medicinal ointment, the middle Cortex Phellodendri n-hexane extract of step (4) is 7-10 part, Radix Sophorae Flavescentis ethanol extraction is 4-7 part, oxtail knee joint ethanol extraction is 8-11 part, Fructus Xanthii water extract is 3-5 part, Flos Campsis water extract is 4-6 part, glycerol is 6-8 part, Brij30 is 6-9 part, starch is 4-5 part.
Described a kind of preparation method for the treatment of paronychial Chinese medicinal ointment, the middle Cortex Phellodendri n-hexane extract of step (4) is 8 parts, Radix Sophorae Flavescentis ethanol extraction is 6 parts, oxtail knee joint ethanol extraction is 9 parts, Fructus Xanthii water extract is 4 parts, Flos Campsis water extract is 5 parts, glycerol is 7 parts, Brij30 is 8 parts, starch is 5 parts.
Beneficial effect: contain natural Chinese medicine extract in Chinese medicinal ointment of the present invention, adding of natural Chinese medicine extract is cured paronychial curative effect be greatly improved to raising Chinese medicinal ointment, especially the extract of good therapeutic effect is had to screen in Fructus Xanthii and Flos Campsis to treatment paronychia, specify that the paronychial composition for the treatment of further, achieve the extraordinary effect for the treatment of paronychia, can effectively and rapidly for curing paronychia.
Detailed description of the invention
Embodiment 1
(1) after Cortex Phellodendri being pulverized, with normal hexane, stirring and leaching is carried out to Cortex Phellodendri, during normal hexane lixiviate, feed liquid weight ratio is 1:7, Extracting temperature is 35 DEG C, extraction time is 3h, and speed of agitator is 150rpm, leaves standstill after lixiviate, get the supernatant, prepare Cortex Phellodendri n-hexane extract by after supernatant vacuum concentration; (2) by Radix Sophorae Flavescentis and the drying of oxtail knee joint, crushed after being dried, carry out agitating heating lixiviate adding dehydrated alcohol, feed liquid weight ratio is 1:5, Extracting temperature is 55 DEG C, and extraction time is 2h, centrifugalize after lixiviate, get supernatant, Radix Sophorae Flavescentis ethanol extraction and oxtail knee joint ethanol extraction will be prepared after supernatant concentration; (3) respectively by Fructus Xanthii and Flos Campsis lyophilization, mechanical activation comminution after lyophilization, hot water stirs's lixiviate is added after pulverizing, feed liquid weight ratio is 1:6, and Extracting temperature is 60 DEG C, and extraction time is 5h, centrifugal after lixiviate, after going precipitation, clear liquid vacuum film is concentrated, concentrate and obtain Fructus Xanthii water extract and Flos Campsis water extract; (4) Cortex Phellodendri n-hexane extract 5 parts, Radix Sophorae Flavescentis ethanol extraction 8 parts, oxtail knee joint ethanol extraction 6 parts, Fructus Xanthii water extract 6 parts, Flos Campsis water extract 3 parts, glycerol 9 parts, Brij30 4 parts, starch 6 parts is got respectively by weight, by above-mentioned various composition mix homogeneously, be prepared as the paronychial Chinese medicinal ointment for the treatment of.
Embodiment 2
(1) after Cortex Phellodendri being pulverized, with normal hexane, stirring and leaching is carried out to Cortex Phellodendri, during normal hexane lixiviate, feed liquid weight ratio is 1:7, Extracting temperature is 35 DEG C, extraction time is 3h, and speed of agitator is 150rpm, leaves standstill after lixiviate, get the supernatant, prepare Cortex Phellodendri n-hexane extract by after supernatant vacuum concentration; (2) by Radix Sophorae Flavescentis and the drying of oxtail knee joint, crushed after being dried, carry out agitating heating lixiviate adding dehydrated alcohol, feed liquid weight ratio is 1:5, Extracting temperature is 55 DEG C, and extraction time is 2h, centrifugalize after lixiviate, get supernatant, Radix Sophorae Flavescentis ethanol extraction and oxtail knee joint ethanol extraction will be prepared after supernatant concentration; (3) respectively by Fructus Xanthii and Flos Campsis lyophilization, mechanical activation comminution after lyophilization, hot water stirs's lixiviate is added after pulverizing, feed liquid weight ratio is 1:6, and Extracting temperature is 60 DEG C, and extraction time is 5h, centrifugal after lixiviate, after going precipitation, clear liquid vacuum film is concentrated, concentrate and obtain Fructus Xanthii water extract and Flos Campsis water extract; (4) Cortex Phellodendri n-hexane extract 13 parts, Radix Sophorae Flavescentis ethanol extraction 3 parts, oxtail knee joint ethanol extraction 13 parts, Fructus Xanthii water extract 2 parts, Flos Campsis water extract 7 parts, glycerol 5 parts, Brij30 10 parts, starch 3 parts is got respectively by weight, by above-mentioned various composition mix homogeneously, be prepared as the paronychial Chinese medicinal ointment for the treatment of.
Embodiment 3
(1) after Cortex Phellodendri being pulverized, with normal hexane, stirring and leaching is carried out to Cortex Phellodendri, during normal hexane lixiviate, feed liquid weight ratio is 1:7, Extracting temperature is 35 DEG C, extraction time is 3h, and speed of agitator is 150rpm, leaves standstill after lixiviate, get the supernatant, prepare Cortex Phellodendri n-hexane extract by after supernatant vacuum concentration; (2) by Radix Sophorae Flavescentis and the drying of oxtail knee joint, crushed after being dried, carry out agitating heating lixiviate adding dehydrated alcohol, feed liquid weight ratio is 1:5, Extracting temperature is 55 DEG C, and extraction time is 2h, centrifugalize after lixiviate, get supernatant, Radix Sophorae Flavescentis ethanol extraction and oxtail knee joint ethanol extraction will be prepared after supernatant concentration; (3) respectively by Fructus Xanthii and Flos Campsis lyophilization, mechanical activation comminution after lyophilization, hot water stirs's lixiviate is added after pulverizing, feed liquid weight ratio is 1:6, and Extracting temperature is 60 DEG C, and extraction time is 5h, centrifugal after lixiviate, after going precipitation, clear liquid vacuum film is concentrated, concentrate and obtain Fructus Xanthii water extract and Flos Campsis water extract; (4) Cortex Phellodendri n-hexane extract 7 parts, Radix Sophorae Flavescentis ethanol extraction 7 parts, oxtail knee joint ethanol extraction 8 parts, Fructus Xanthii water extract 5 parts, Flos Campsis water extract 4 parts, glycerol 8 parts, Brij30 9 parts, starch 5 parts is got respectively by weight, by above-mentioned various composition mix homogeneously, be prepared as the paronychial Chinese medicinal ointment for the treatment of.
Embodiment 4
(1) after Cortex Phellodendri being pulverized, with normal hexane, stirring and leaching is carried out to Cortex Phellodendri, during normal hexane lixiviate, feed liquid weight ratio is 1:7, Extracting temperature is 35 DEG C, extraction time is 3h, and speed of agitator is 150rpm, leaves standstill after lixiviate, get the supernatant, prepare Cortex Phellodendri n-hexane extract by after supernatant vacuum concentration; (2) by Radix Sophorae Flavescentis and the drying of oxtail knee joint, crushed after being dried, carry out agitating heating lixiviate adding dehydrated alcohol, feed liquid weight ratio is 1:5, Extracting temperature is 55 DEG C, and extraction time is 2h, centrifugalize after lixiviate, get supernatant, Radix Sophorae Flavescentis ethanol extraction and oxtail knee joint ethanol extraction will be prepared after supernatant concentration; (3) respectively by Fructus Xanthii and Flos Campsis lyophilization, mechanical activation comminution after lyophilization, hot water stirs's lixiviate is added after pulverizing, feed liquid weight ratio is 1:6, and Extracting temperature is 60 DEG C, and extraction time is 5h, centrifugal after lixiviate, after going precipitation, clear liquid vacuum film is concentrated, concentrate and obtain Fructus Xanthii water extract and Flos Campsis water extract; (4) Cortex Phellodendri n-hexane extract 10 parts, Radix Sophorae Flavescentis ethanol extraction 4 parts, oxtail knee joint ethanol extraction 11 parts, Fructus Xanthii water extract 3 parts, Flos Campsis water extract 6 parts, glycerol 6 parts, Brij30 6 parts, starch 4 parts is got respectively by weight, by above-mentioned various composition mix homogeneously, be prepared as the paronychial Chinese medicinal ointment for the treatment of.
Embodiment 5
(1) after Cortex Phellodendri being pulverized, with normal hexane, stirring and leaching is carried out to Cortex Phellodendri, during normal hexane lixiviate, feed liquid weight ratio is 1:7, Extracting temperature is 35 DEG C, extraction time is 3h, and speed of agitator is 150rpm, leaves standstill after lixiviate, get the supernatant, prepare Cortex Phellodendri n-hexane extract by after supernatant vacuum concentration; (2) by Radix Sophorae Flavescentis and the drying of oxtail knee joint, crushed after being dried, carry out agitating heating lixiviate adding dehydrated alcohol, feed liquid weight ratio is 1:5, Extracting temperature is 55 DEG C, and extraction time is 2h, centrifugalize after lixiviate, get supernatant, Radix Sophorae Flavescentis ethanol extraction and oxtail knee joint ethanol extraction will be prepared after supernatant concentration; (3) respectively by Fructus Xanthii and Flos Campsis lyophilization, mechanical activation comminution after lyophilization, hot water stirs's lixiviate is added after pulverizing, feed liquid weight ratio is 1:6, and Extracting temperature is 60 DEG C, and extraction time is 5h, centrifugal after lixiviate, after going precipitation, clear liquid vacuum film is concentrated, concentrate and obtain Fructus Xanthii water extract and Flos Campsis water extract; (4) Cortex Phellodendri n-hexane extract 8 parts, Radix Sophorae Flavescentis ethanol extraction 6 parts, oxtail knee joint ethanol extraction 9 parts, Fructus Xanthii water extract 4 parts, Flos Campsis water extract 5 parts, glycerol 7 parts, Brij30 8 parts, starch 5 parts is got respectively by weight, by above-mentioned various composition mix homogeneously, be prepared as the paronychial Chinese medicinal ointment for the treatment of.
Comparative example 1
(1) after Cortex Phellodendri being pulverized, with normal hexane, stirring and leaching is carried out to Cortex Phellodendri, during normal hexane lixiviate, feed liquid weight ratio is 1:7, Extracting temperature is 35 DEG C, extraction time is 3h, and speed of agitator is 150rpm, leaves standstill after lixiviate, get the supernatant, prepare Cortex Phellodendri n-hexane extract by after supernatant vacuum concentration; (2) by Radix Sophorae Flavescentis and the drying of oxtail knee joint, crushed after being dried, carry out agitating heating lixiviate adding dehydrated alcohol, feed liquid weight ratio is 1:5, Extracting temperature is 55 DEG C, and extraction time is 2h, centrifugalize after lixiviate, get supernatant, Radix Sophorae Flavescentis ethanol extraction and oxtail knee joint ethanol extraction will be prepared after supernatant concentration; (3) Cortex Phellodendri n-hexane extract 5 parts, Radix Sophorae Flavescentis ethanol extraction 8 parts, oxtail knee joint ethanol extraction 6 parts, glycerol 9 parts, Brij30 4 parts, starch 6 parts is got respectively by weight, by above-mentioned various composition mix homogeneously, be prepared as the paronychial Chinese medicinal ointment for the treatment of.
Comparative example 2
(1) after Cortex Phellodendri being pulverized, with normal hexane, stirring and leaching is carried out to Cortex Phellodendri, during normal hexane lixiviate, feed liquid weight ratio is 1:7, Extracting temperature is 35 DEG C, extraction time is 3h, and speed of agitator is 150rpm, leaves standstill after lixiviate, get the supernatant, prepare Cortex Phellodendri n-hexane extract by after supernatant vacuum concentration; (2) Radix Sophorae Flavescentis is dry, crushed after being dried, carries out agitating heating lixiviate adding dehydrated alcohol, feed liquid weight ratio is 1:5, and Extracting temperature is 55 DEG C, and extraction time is 2h, centrifugalize after lixiviate, gets supernatant, will prepare Radix Sophorae Flavescentis ethanol extraction after supernatant concentration; (3) respectively by Fructus Xanthii and Flos Campsis lyophilization, mechanical activation comminution after lyophilization, hot water stirs's lixiviate is added after pulverizing, feed liquid weight ratio is 1:6, and Extracting temperature is 60 DEG C, and extraction time is 5h, centrifugal after lixiviate, after going precipitation, clear liquid vacuum film is concentrated, concentrate and obtain Fructus Xanthii water extract and Flos Campsis water extract; (4) Cortex Phellodendri n-hexane extract 5 parts, Radix Sophorae Flavescentis ethanol extraction 8 parts, oxtail knee joint ethanol extraction 6 parts, Fructus Xanthii water extract 6 parts, Flos Campsis water extract 3 parts, glycerol 9 parts, Brij30 4 parts, starch 6 parts is got respectively by weight, by above-mentioned various composition mix homogeneously, be prepared as the paronychial Chinese medicinal ointment for the treatment of.
Comparative example 3
Prepared by the raw material of license notification number to be the plaster of CN 102743454 be following weight fraction (gram): Radix Salviae Miltiorrhizae 45 parts, YUNNAN BAIYAO 45 parts, Rhizoma Coptidis 20 parts, Radix Et Rhizoma Rhei 20 parts, Borneolum Syntheticum 30 parts, Eupolyphaga Seu Steleophaga 40 parts, Radix Sophorae Flavescentis 40 parts, Olibanum 40 parts "; after mixing; steep 10 days with the 95% ethanol merceration of 2000 parts; filter; obtain filtrate; vacuum drying, pulverize, obtain powder for subsequent use; Posaconazole 4 parts, terbinafine HCl 4 parts, with 95% appropriate dissolve with ethanol, obtain liquid for subsequent use; Get powder for subsequent use, liquid for subsequent use, mix with nanometer silver 8 parts, 1000 parts, vaseline, obtain unguentum of the present invention.
Paronychia patient is divided into 8 groups, and often organizing number is 25 people, and smear the Chinese medicinal ointment by embodiment 1 to 5 and contrast 1 to 3 respectively, smear 1 every day, after smearing 5 days, observe the paronychial healing number of patient, statistical result is shown in following.
The healing number of embodiment 1 to 5 is as follows:
The healing number of comparative example 1 to 3 is as follows:
| Comparative example 1 | Comparative example 2 | Comparative example 3 | |
| Cure number | 15 | 14 | 17 |
As can be seen from the table, Chinese medicinal ointment of the present invention is to the cure rate of paronychial cure rate higher than the Chinese medicinal ointment of comparative example 1 to 3.
Claims (10)
1. treat a paronychial Chinese medicinal ointment, it is characterized in that, the paronychial Chinese medicinal ointment of described treatment comprises the composition of following weight parts:
Cortex Phellodendri n-hexane extract 5-13 part,
Radix Sophorae Flavescentis ethanol extraction 3-8 part,
Oxtail knee joint ethanol extraction 6-13 part,
Fructus Xanthii water extract 2-6 part,
Flos Campsis water extract 3-7 part,
Glycerol 5-9 part,
Brij30 4-10 part,
Starch 3-6 part.
2. one according to claim 1 treats paronychial Chinese medicinal ointment, it is characterized in that, the paronychial Chinese medicinal ointment of described treatment comprises the composition of following weight parts:
Cortex Phellodendri n-hexane extract 7-10 part,
Radix Sophorae Flavescentis ethanol extraction 4-7 part,
Oxtail knee joint ethanol extraction 8-11 part,
Fructus Xanthii water extract 3-5 part,
Flos Campsis water extract 4-6 part,
Glycerol 6-8 part,
Brij30 6-9 part,
Starch 4-5 part.
3. one according to claim 1 treats paronychial Chinese medicinal ointment, it is characterized in that, the paronychial Chinese medicinal ointment of described treatment comprises the composition of following weight parts:
Cortex Phellodendri n-hexane extract 8 parts,
Radix Sophorae Flavescentis ethanol extraction 6 parts,
Oxtail knee joint ethanol extraction 9 parts,
Fructus Xanthii water extract 4 parts,
Flos Campsis water extract 5 parts,
Glycerol 7 parts,
Brij30 8 parts,
Starch 5 parts.
4. a kind of preparation method for the treatment of paronychial Chinese medicinal ointment according to claim 1, it is characterized in that, described preparation method comprises the steps:
(1) after being pulverized by Cortex Phellodendri, with normal hexane, stirring and leaching is carried out to Cortex Phellodendri, leave standstill after lixiviate, get the supernatant, prepare Cortex Phellodendri n-hexane extract by after supernatant vacuum concentration;
(2) Radix Sophorae Flavescentis and oxtail knee joint is dry, crushed after being dried, carry out agitating heating lixiviate adding dehydrated alcohol, centrifugalize after lixiviate, gets supernatant, will prepare Radix Sophorae Flavescentis ethanol extraction and oxtail knee joint ethanol extraction after supernatant concentration;
(3) respectively by Fructus Xanthii and Flos Campsis lyophilization, mechanical activation comminution after lyophilization, adds hot water stirs's lixiviate after pulverizing, centrifugal after lixiviate, after going precipitation, is concentrated by clear liquid vacuum film, concentrates and obtains Fructus Xanthii water extract and Flos Campsis water extract;
(4) Cortex Phellodendri n-hexane extract 5-13 part, Radix Sophorae Flavescentis ethanol extraction 3-8 part, oxtail knee joint ethanol extraction 6-13 part, Fructus Xanthii water extract 2-6 part, Flos Campsis water extract 3-7 part, glycerol 5-9 part, Brij30 4-10 part, starch 3-6 part is got respectively by weight, by above-mentioned various composition mix homogeneously, be prepared as the paronychial Chinese medicinal ointment for the treatment of.
5. a kind of preparation method for the treatment of paronychial Chinese medicinal ointment according to claim 4, is characterized in that, in preparation method step (1), during normal hexane lixiviate, feed liquid weight ratio is 1:7, and Extracting temperature is 35 DEG C, and extraction time is 3h, and speed of agitator is 150rpm.
6. a kind of preparation method for the treatment of paronychial Chinese medicinal ointment according to claim 4, is characterized in that, be 1:5 to feed liquid weight ratio when Radix Sophorae Flavescentis and the lixiviate of oxtail knee joint in preparation method step (2), Extracting temperature is 55 DEG C, and extraction time is 2h.
7. a kind of preparation method for the treatment of paronychial Chinese medicinal ointment according to claim 4, is characterized in that, be 1:6 to feed liquid weight ratio when Fructus Xanthii and Flos Campsis lixiviate in preparation method step (3), Extracting temperature is 60 DEG C, and extraction time is 5h.
8. a kind of preparation method for the treatment of paronychial Chinese medicinal ointment according to claim 4, is characterized in that, in preparation method step (3), sublimation drying is 10h-20h.
9. a kind of preparation method for the treatment of paronychial Chinese medicinal ointment according to claim 4, it is characterized in that, Cortex Phellodendri n-hexane extract is 7-10 part in preparation method step (4), Radix Sophorae Flavescentis ethanol extraction is 4-7 part, oxtail knee joint ethanol extraction is 8-11 part, Fructus Xanthii water extract is 3-5 part, Flos Campsis water extract is 4-6 part, glycerol is 6-8 part, Brij30 is 6-9 part, starch is 4-5 part.
10. a kind of preparation method for the treatment of paronychial Chinese medicinal ointment according to claim 4, it is characterized in that, Cortex Phellodendri n-hexane extract is 8 parts in preparation method step (4), Radix Sophorae Flavescentis ethanol extraction is 6 parts, oxtail knee joint ethanol extraction is 9 parts, Fructus Xanthii water extract is 4 parts, Flos Campsis water extract is 5 parts, glycerol is 7 parts, Brij30 is 8 parts, starch is 5 parts.
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|---|---|---|---|---|
| CN105687442A (en) * | 2016-03-16 | 2016-06-22 | 卢连伟 | External medicament for treating paronychia and preparation method thereof |
| CN113662739A (en) * | 2021-08-20 | 2021-11-19 | 刘浩泉 | Ice compress and manufacturing method thereof |
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Application publication date: 20150715 |