CN102743437B - Traditional Chinese medicine composition having function of clearing vivotoxin and preparing method thereof - Google Patents
Traditional Chinese medicine composition having function of clearing vivotoxin and preparing method thereof Download PDFInfo
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Abstract
The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition having the function of clearing vivotoxin and a clinical preparation thereof. The traditional Chinese medicine composition having the function of clearing vivotoxin is prepared by sappanwood, lycopodium clavatum, garden balsam stem, gamboges, radix angelicae, sculellaria barbata and ground sesameseed oil which are mutually influenced and come into play in synergistically. The traditional Chinese medicine composition has the effects of promoting blood circulation to remove blood stasis, removing spasm, easing pain, dispersing swelling, dredging collaterals, expelling toxin and detoxifying and can be used for treating cervical bone hyperplasia, spinal canal stenosis, slipped discs, ischioneuralgia, acne, acne rosacea, herpes zoster and other diseases. Simultaneously, the medicine materials used by traditional Chinese medicine composition are nontoxic, and the traditional Chinese medicine composition is small in medicine dependence after long term usage, low in price and suitable for short-term and long-term use and has wide market prospect.
Description
Technical field
The present invention relates to tcm field, relate to specifically a kind of Chinese medicine composition with the effect of removing vivotoxin and preparation method thereof.
Background technology
" toxin expelling ", became a kind of fashionable regimen of white collar family in recent years gradually, and the toxin expelling mode that beauty parlor and health product businessman release is also multifarious: medicine toxin expelling, Spa toxin expelling, lympha toxin expelling, intestinal toxin expelling, champignon toxin expelling etc.What is toxin on earth?
" poison " refers to harmful material, comprises that the refuse produced in metabolic processes from materials such as body fat mass in human body, sugar, protein, as peptide class, ammonia, a small amount of hydrogen sulfide and indole etc. from the pressure of external environment and pollution, antibacterial, virus.In the traditional Chinese medical science, so-called " poison ", simply say the two kinds of situations that mainly contain: a kind of is that poison is evil, by diseases caused by exogenous pathogenic factor pathogen invasion human body, is caused, such as anemofrigid cold, get angry etc., this situation is generally directly visible " poison "; Another kind is due to capable not smooth through fate, the stagnant or expectorant, silt, stagnant etc. through vapour lock that cause.
Modern metropolitan cities rhythm is accelerated, and work, life stress are large, allows the people always in the nervous mental status, once pressure surpasses the range of accommodation of human body self, will cause internal organs, QI and blood dysfunction, thereby produce toxin, and unavoidable meeting causes a lot of diseases.As poisonous refuse and phat fat are attached in blood vessel and hinder the unimpeded of blood, these get clogged at leisure blood vessel meeting hardening, thickening, the blood vessel that enough blood is got clogged via these that heart must more be required great effort is delivered in cell, so that causes hypertension, blood clotting, heart disease and stroke.With being being connected of bone soft, resilient soft tissue covers bone, can cushion joint and reduce the friction injury.Also have joint fluid Castor Oil joint in the inside, joint, joint fluid must be to clean, do not have toxin, just can make joint healthy and strong and flexible.When toxin gathers, joint just can start enlargement, bone distal roughened and indentation, and cartilage becomes dry and frangible, and intraarticular secretions is killed fully at leisure, and the friction of misery each other between bone has formed " arthritis ".When toxin hurts muscle and blood vessel, just form " rheumatism ".The traditional Chinese medical science thinks that acne is in blood, to have heat in blood to exist for another example, and the poison in blood is by the five internal organs intrinsic heat, injects blood vessels, and in meridians, vim and vigour are got along well in addition, and external damp, pathogenic heat damage blood of human body, cause acne.Also some theories of Chinese medical science are thought, tumor is also the toxic waste due to accumulation, are gathered in each tissue of health caused.Therefore a kind of toxin that can get rid of in human body is provided, strengthens body immunity, to reducing and preventing the diseases such as cardiovascular and cerebrovascular disease, rheumatic osteopathia, acne, cancer significant.
Summary of the invention
In view of this, the object of the invention is to provide a kind of Chinese medicine composition of removing the vivotoxin effect that has, and the described preparation method with Chinese medicine composition of removing the vivotoxin effect also is provided simultaneously.
For realizing purpose of the present invention, the present invention adopts following technical scheme:
A kind of Chinese medicine composition with the effect of removing vivotoxin, made by following weight portion raw material: Lignum Sappan 30-70 part, Herba Lycopodii 30-70 part, Herba speranskiae tuberculatae 30-70 part, Resina garciniae 0.5-2 part, Radix Angelicae Dahuricae 10-40 part, Herba Scutellariae Barbatae 30-70 part, ground sesameseed oil 300-400 part.
Chinese medicine composition of the present invention selects Lignum Sappan, Herba Lycopodii, Herba speranskiae tuberculatae, Resina garciniae, the Radix Angelicae Dahuricae, Herba Scutellariae Barbatae and ground sesameseed oil seven flavor Chinese crude drugs to make, and has the effect of blood circulation promoting and blood stasis dispelling, spasmolysis and analgesia, detumescence dredging collateral, dispelling toxicity, detoxicating.
Wherein, Lignum Sappan is clinical Chinese medicine commonly used, has another name called Soviet Union's a tree, used in making timber for boats, the Soviet side, and lignum sappan, lowland swamp wood, palm fibre wood, Ramulus et Folium Bischofiae Javanicae, red bavin, be the dry duramen of Caesalpiniaceae Caesalpinia plant Lignum Sappan.Lignum Sappan sweet in the mouth, salty, property is flat, and nontoxic, GUIXIN, liver, stomach, large intestine channel, have the effect of promoting the circulation of blood, removing blood stasis with potent drugs, detumescence, pain relieving, is usually used in controlling married woman's vim and vigour cardiac and abdominal pain, amenorrhea, postnatal blood stasis distending pain dyspnea with rapid respiration, dysentery, tetanus, carbuncle, flutters and damage that the stasis of blood is stagnant has a pain.
Herba Lycopodii, have another name called Radix et Rhizoma Smilacis Ripariae, large along muscle rattan, Radix Schisandrae Micranthae, the Radix Stemonae stretch muscle, water shakes bamboo, Herba Lycopodii, Herba Poae Sphondylodis, is the herb of Lycopodiaceae Lycopodium plant Lycopodium clavatum Lycopodium japonicum Thunb..Herba Lycopodii is warm in nature, bitter in the mouth is hot, is included into Liver Channel, has the effect of expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral, is mainly used in the disease of anemofrigid-damp arthralgia, muscle arteries and veins contracture pain carbuncle, and external can be controlled osteopatia sprain and swell and ache.
Herba speranskiae tuberculatae, latin name ViciaamoenaFisch, have another name called to fall bean seedling, mountain Semen sojae atricolor, Herba Viciae Amoenae, is the young stem and leaf of leguminous plant Herba Viciae Amoenae.Herba speranskiae tuberculatae sweet in the mouth, hardship, warm in nature, there is wind-damp dispelling, invigorate blood circulation, the effect such as relaxing muscles and tendons, pain relieving, cure mainly rheumatalgia, sprain and contusion wound, innominate toxic swelling, eczema scrotum.
Resina garciniae, have another name called beautiful yellow, month Huang, is the colloid resin of dicotyledon medicine Garcinia maingayii Resina garciniae.Sour-puckery flavor, poisonous, there is detumescence, removing toxic substances, hemostasis, parasite killing, cure mainly swollen ulcer drug, stubborn dermatitis malignant boil, bleeding due to trauma, ulcerative gingivitis decayed tooth, burn.
The Radix Angelicae Dahuricae, for the root of samphire Yu Radix Angelicae Dahuricae, Xingan's Radix Angelicae Dahuricae, angelica anomala, Radix angelicae dahuricae or Yunnan cattle Radix Saposhnikoviae warm in nature, acrid in the mouth, attach to the lung and stomach meridians, effect with expelling wind and cold, understand things pain-stopping, detumescence and apocenosis, dampness leukorrhagia stopping, cure mainly the diseases such as headache, toothache, nasal sinusitis, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus.
Herba Scutellariae Barbatae, have another name called also head grass, narrow leaf Herba Scutellariae indicae, toothbrush grass, Herba Scutellariae Darbatae, Herba Scutellariae Barbatae, Herba Carpesii Cernui, Aleuritopteris argentea (Gmel.) Fee.Herba Scutellariae Barbatae acrid in the mouth, hardship, cold in nature, return lung, liver, kidney channel, there is the effect of the hemostasis of heat-clearing and toxic substances removing, dissipating blood stasis, inducing diuresis to remove edema, cure mainly the pyretic toxicity carbuncle, have sore throat, lung abscess, acute appendicitis, scrofula, venom, traumatic injury, haematemesis, epistaxis, stranguria with blood, edema, ascites and cancer.
Ground sesameseed oil, because of with fragrance striking the nose, aromatic flavor is tempting gains the name.Ground sesameseed oil also has the effect of the health care of its uniqueness.Introduce Semen Sesami " physical strength profiting, longue meat, fill out brains, for a long time clothes are made light of one's life by commiting suicide not oldly, hard muscles and bones, improve visual and auditory acuity, anti-ly hunger and thirst, and prolongs life " in Compendium of Material Medica.Ground sesameseed oil has the effect of protection blood vessel, loosening bowel to relieve constipation, skin care.
Wherein, as preferably, described have a Chinese medicine composition of removing the vivotoxin effect, by following weight portion raw material, made: 50 parts of Lignum Sappans, 50 parts of Herba Lycopodiis, 50 parts of Herba speranskiae tuberculataes, 1 part of Resina garciniae, 30 parts of the Radixs Angelicae Dahuricae, 50 parts of Herba Scutellariae Barbataes, 350 parts of ground sesameseed oils.
The present invention also provides the clinical preparation of described Chinese medicine composition.Those skilled in the art can add Chinese medicine composition of the present invention according to different patients' demand that to prepare different dosage form be required various pharmaceutically conventional adjuvants, as disintegrating agent, lubricant, emulsifying agent, binding agent etc., with conventional method of Chinese medicinal, through routine processing, the direct or indirect acceptable adjuvant common dosage forms processed pharmaceutically of adding is as capsule, unguentum, tablet, pill, oral liquid, granule, powder etc.
Preferably, the clinical preparation of Chinese medicine composition of the present invention is Emulsion, unguentum, gel or liniment, and compliance is good, with strong points, and curative effect is obvious.Unguentum Emulsion, unguentum, gel or the liniment of external Chinese medicine composition of the present invention, can blood circulation promoting and blood stasis dispelling, spasmolysis and analgesia, detumescence dredging collateral, dispelling toxicity, detoxicating, and penetration is strong, absorbs soon, and treatment time is short.
The present invention also provides the described preparation method with Chinese medicine composition of removing the vivotoxin effect, be ground into powder for getting 30-70 weight portion Lignum Sappan, 30-70 weight portion Herba Lycopodii, 30-70 weight portion Herba speranskiae tuberculatae, 0.5-2 weight portion Resina garciniae, the 10-40 weight portion Radix Angelicae Dahuricae and 30-70 weight Herba Scutellariae Barbatae, with 300-400 weight portion ground sesameseed oil, be in harmonious proportion and get final product.
Wherein, as preferably, the described preparation method with Chinese medicine composition of removing the vivotoxin effect, be ground into powder for getting 50 weight portion Lignum Sappans, 50 weight portion Herba Lycopodiis, 50 weight portion Herba speranskiae tuberculataes, 1 weight portion Resina garciniae, the 30 weight portion Radixs Angelicae Dahuricae and 50 weight Herba Scutellariae Barbataes, with 350 weight portion ground sesameseed oils, be in harmonious proportion and get final product.
The Chinese medicine composition that the present invention also provides above-mentioned preparation method to prepare.
Using dosage and using method with Chinese medicine composition of removing the vivotoxin effect of the present invention depends on factors, comprises activity intensity, Time of Administration, metabolic rate, coincident with severity degree of condition and diagnosis and treatment doctor's the subjective judgment of patient's age, body weight, sex, natural health situation, nutriture, compound.Those skilled in the art can easily determine using dosage and the using method of pharmaceutical composition according to above-mentioned factor.
The present invention in 100 routine patients with acne, smears Chinese medicine composition ointment of the present invention after 30 days through clinical observation on the therapeutic effect, cures 90 examples, and cure rate accounts for 90%, 6 examples that take a turn for the better, and obvious effective rate accounts for 6%, invalid 4 examples, total effective rate is 96%.In 100 routine acne rosacea patients, smear Chinese medicine composition ointment of the present invention after 30 days, cure 92 examples, cure rate accounts for 92%, 3 examples that take a turn for the better, obvious effective rate accounts for 3%, and total effective rate is 95%.In 100 routine herpes zoster patients, smear Chinese medicine composition ointment of the present invention after 3 days, cure 96 examples, cure rate accounts for 96%, 3 examples that take a turn for the better, obvious effective rate accounts for 3%, and total effective rate is 99%.In 100 routine hyperosteogeny of cervical vertebra patients, smear Chinese medicine composition ointment of the present invention after 30 days, cure 94 examples, cure rate accounts for 94%, 4 examples that take a turn for the better, obvious effective rate accounts for 4%, and total effective rate is 98%.In 100 routine prolapse of lumbar intervertebral disc patients, smear Chinese medicine composition ointment of the present invention after 30 days, cure 90 examples, cure rate accounts for 90%, 5 examples that take a turn for the better, obvious effective rate accounts for 5%, and total effective rate is 95%.
Chinese medicine composition with the effect of removing vivotoxin of the present invention, by Lignum Sappan, Herba Lycopodii, Herba speranskiae tuberculatae, Resina garciniae, the Radix Angelicae Dahuricae, Herba Scutellariae Barbatae and ground sesameseed oil, influenced each other, synergism, blood circulation promoting and blood stasis dispelling, spasmolysis and analgesia, detumescence dredging collateral, dispelling toxicity, detoxicating, for diseases such as hyperosteogeny of cervical vertebra, spinal canal stenosis, prolapse of lumbar intervertebral disc, hip gout, acne, acne rosacea, herpes zoster, herpes zoster.The medical material used of the present invention simultaneously is all nontoxic, and the life-time service drug dependence is little, and cheap, is applicable to short-term and life-time service, has wide market prospect.
The specific embodiment
The embodiment of the invention discloses a kind of Chinese medicine composition with the effect of removing vivotoxin and preparation method thereof.Those skilled in the art can use for reference this paper content, suitably improve technological parameter and realize.Special needs to be pointed out is, all similar replacements and change apparent to those skilled in the artly, they all are deemed to be included in the present invention.Product of the present invention is described by preferred embodiment, the related personnel obviously can be within not breaking away from content of the present invention, spirit and scope to product as herein described with method is changed or suitably change and combination, realize and apply the technology of the present invention.
In order further to understand the present invention, below in conjunction with embodiment, the present invention is described in detail.
Embodiment 1: the Chinese medicine composition with the effect of removing vivotoxin of the present invention
Described Chinese medicine composition is to be made by the crude drug of following weight portion:
Lignum Sappan 30-70 part, Herba Lycopodii 30-70 part, Herba speranskiae tuberculatae 30-70 part, Resina garciniae 0.5-2 part, Radix Angelicae Dahuricae 10-40 part, Herba Scutellariae Barbatae 30-70 part, ground sesameseed oil 300-400 part.
Preparation method is that Lignum Sappan, Herba Lycopodii, Herba speranskiae tuberculatae, Resina garciniae, the Radix Angelicae Dahuricae and the Herba Scutellariae Barbatae of getting described weight are ground into powder, and ground sesameseed oil is in harmonious proportion and get final product.
Embodiment 2: the ointment with the effect of removing vivotoxin of the present invention
Get Lignum Sappan 50g, Herba Lycopodii 50g, Herba speranskiae tuberculatae 50g, Resina garciniae 1g, Radix Angelicae Dahuricae 30g, Herba Scutellariae Barbatae 50g are ground into powder, the 350g ground sesameseed oil is in harmonious proportion, and with medical petrolatum oil, by weight the ratio of 1:15 ~ 1:20, mixes, packing and get final product stirs.
Embodiment 3: the liniment with the effect of removing vivotoxin of the present invention
Get Lignum Sappan 50g, Herba Lycopodii 50g, Herba speranskiae tuberculatae 50g, Resina garciniae 1g, Radix Angelicae Dahuricae 30g, Herba Scutellariae Barbatae 50g are ground into powder, the 350g ground sesameseed oil is in harmonious proportion, and with the 150g polyvinyl formal-acetal, mixes, ethanol adds to 1000g, packing and get final product stirs.
Embodiment 4: the observation of curative effect of Chinese medicine composition of the present invention
Observe application Chinese medicine composition of the present invention and there is the effect of removing the vivotoxin effect.
Select 200 routine patients with acne, be divided at random experimental group and matched group, every group of 100 examples, experimental group male 101 people wherein, women 99 people; Matched group male 103 people, women 97 people.
Therapeutic Method: experimental group is smeared the ointment of Chinese medicine composition of the present invention in affected part, every day three times, use continuously 30 days, during avoid livingly, cold, pungent, stop other Chinese medicine and western medicine and health product.Matched group is smeared tretinoin ointment in affected part, every day three times, use continuously 30 days, during avoid livingly, cold, pungent, stop other Chinese medicine and western medicine and health product.
The curative effect judgment criteria:
Cure: acne, pimple or pustule disappear, skin healing;
Produce effects: acne, pimple or pustule reduce;
Invalid: cardinal symptom does not alleviate, and acne, pimple or pustule increase the weight of, and forms cyst.
Statistical result: the present invention has obtained curative effect preferably clinically, in 100 routine patients with acne, smears Chinese medicine composition ointment of the present invention after 30 days, cures 90 examples, and cure rate accounts for 90%, 6 examples that take a turn for the better, and obvious effective rate accounts for 6%, invalid 4 examples, total effective rate is 96%.The matched group cure rate is that 73%, two group of cure rate relatively has significant difference (P<0.05).
In addition, adopt and use the same method to acne rosacea, the patient of herpes zoster, hyperosteogeny of cervical vertebra, prolapse of lumbar intervertebral disc carries out clinical observation on the therapeutic effect.In 100 routine acne rosacea patients, smear Chinese medicine composition ointment of the present invention after 30 days, cure 92 examples, cure rate accounts for 92%, 3 examples that take a turn for the better, obvious effective rate accounts for 3%, and total effective rate is 95%.In 100 routine herpes zoster patients, smear Chinese medicine composition ointment of the present invention after 3 days, cure 96 examples, cure rate accounts for 96%, 3 examples that take a turn for the better, obvious effective rate accounts for 3%, and total effective rate is 99%.In 100 routine hyperosteogeny of cervical vertebra patients, smear Chinese medicine composition ointment of the present invention after 30 days, cure 94 examples, cure rate accounts for 94%, 4 examples that take a turn for the better, obvious effective rate accounts for 4%, and total effective rate is 98%.In 100 routine prolapse of lumbar intervertebral disc patients, smear Chinese medicine composition ointment of the present invention after 30 days, cure 90 examples, cure rate accounts for 90%, 5 examples that take a turn for the better, obvious effective rate accounts for 5%, and total effective rate is 95%.
Embodiment 5: the clinical observation of Chinese medicine composition of the present invention
The marquis, man, 48 years old, the autoworker, suffer from three-hypers disease, and blood fat is high, blood glucose is high, hypertension, and there is the pox cicatrix back many places, shirtfront, new acne is arranged simultaneously, after shirtfront back is smeared 3 courses for the treatment of of ointment (10 days each courses for the treatment of) of Chinese medicine composition of the present invention, vivotoxin reduces, blood fat, blood glucose, Blood pressure drop, the acne recovery from illness, the pox cicatrix is thin out.
Xiao, the female, 76 years old, the retired worker, suffered from pathogenic wind-warm arthromyodynia, hyperosteogeny, spinal canal stenosis, whole body has innominate toxic swelling, the back of the hand swelling has impetigo, and after cervical vertebra, back and hand are smeared 3 courses for the treatment of of ointment (10 days each courses for the treatment of) of Chinese medicine composition of the present invention, the back of the hand swelling disappears, the impetigo recovery from illness, the hyperosteogeny remission.
Liu, the female, 46 years old, the housewife, suffer from spinal canal stenosis, hyperosteogeny of cervical vertebra, cause cerebral blood supply insufficiency, recovery from illness after 4 courses for the treatment of of ointment (10 days each courses for the treatment of) of through cervical vertebra, back, smearing Chinese medicine composition of the present invention, cervical vertebra ache, have a stiff neck, the transference cures such as upper myasthenia of limbs, numbness of the fingers.
The explanation of above embodiment is just for helping to understand method of the present invention and core concept thereof.It should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention, can also carry out some improvement and modification to the present invention, these improvement and modification also fall in the protection domain of the claims in the present invention.
Claims (7)
1. one kind has the Chinese medicine composition of removing the vivotoxin effect, it is characterized in that, by following weight portion raw material, is made: Lignum Sappan 30-70 part, Herba Lycopodii 30-70 part, Herba speranskiae tuberculatae 30-70 part, Resina garciniae 0.5-2 part, Radix Angelicae Dahuricae 10-40 part, Herba Scutellariae Barbatae 30-70 part, ground sesameseed oil 300-400 part.
2. Chinese medicine composition according to claim 1, is characterized in that, by following weight portion raw material, made: 50 parts of Lignum Sappans, 50 parts of Herba Lycopodiis, 50 parts of Herba speranskiae tuberculataes, 1 part of Resina garciniae, 30 parts of the Radixs Angelicae Dahuricae, 50 parts of Herba Scutellariae Barbataes, 350 parts of ground sesameseed oils.
3. the clinical preparation that comprises claim 1 or 2 described Chinese medicine composition.
4. clinical preparation according to claim 3, is characterized in that, it is Emulsion, unguentum, gel or liniment.
5. the preparation method with Chinese medicine composition of removing the vivotoxin effect, it is characterized in that, get 30-70 weight portion Lignum Sappan, 30-70 weight portion Herba Lycopodii, 30-70 weight portion Herba speranskiae tuberculatae, 0.5-2 weight portion Resina garciniae, the 10-40 weight portion Radix Angelicae Dahuricae and 30-70 weight Herba Scutellariae Barbatae and be ground into powder, with 300-400 weight portion ground sesameseed oil, be in harmonious proportion and get final product.
6. the preparation method with Chinese medicine composition of removing the vivotoxin effect, it is characterized in that, get 50 weight portion Lignum Sappans, 50 weight portion Herba Lycopodiis, 50 weight portion Herba speranskiae tuberculataes, 1 weight portion Resina garciniae, the 30 weight portion Radixs Angelicae Dahuricae and 50 weight Herba Scutellariae Barbataes and be ground into powder, with 350 weight portion ground sesameseed oils, be in harmonious proportion and get final product.
7. the Chinese medicine composition prepared according to the described preparation method of claim 5 or 6.
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| Title |
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| 刘雁，等.中医药治疗痤疮作用机制研究进展.《辽宁中医药大学学报》.2010,第12卷(第4期),第81-82页. * |
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