CN102740853B - 可可碱的药物组合及其在治疗中的用途 - Google Patents

可可碱的药物组合及其在治疗中的用途 Download PDF

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Publication number
CN102740853B
CN102740853B CN201080051628.4A CN201080051628A CN102740853B CN 102740853 B CN102740853 B CN 102740853B CN 201080051628 A CN201080051628 A CN 201080051628A CN 102740853 B CN102740853 B CN 102740853B
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CN
China
Prior art keywords
theobromine
codeine
pharmaceutical composition
reagent
cough
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201080051628.4A
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English (en)
Chinese (zh)
Other versions
CN102740853A (zh
Inventor
约翰·布鲁
罗宾·马克·班尼斯特尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocopea Ltd
Original Assignee
Infirst Healthcare Ltd
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Filing date
Publication date
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Publication of CN102740853A publication Critical patent/CN102740853A/zh
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Publication of CN102740853B publication Critical patent/CN102740853B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN201080051628.4A 2009-11-13 2010-11-12 可可碱的药物组合及其在治疗中的用途 Expired - Fee Related CN102740853B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0919893.8 2009-11-13
GBGB0919893.8A GB0919893D0 (en) 2009-11-13 2009-11-13 Drug composition and its use in therapy
PCT/GB2010/051896 WO2011058374A1 (en) 2009-11-13 2010-11-12 Drug combination with theobromine and its use in therapy

Publications (2)

Publication Number Publication Date
CN102740853A CN102740853A (zh) 2012-10-17
CN102740853B true CN102740853B (zh) 2015-04-08

Family

ID=41509327

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201080051628.4A Expired - Fee Related CN102740853B (zh) 2009-11-13 2010-11-12 可可碱的药物组合及其在治疗中的用途

Country Status (19)

Country Link
EP (1) EP2498776A1 (enExample)
JP (2) JP2013510842A (enExample)
CN (1) CN102740853B (enExample)
AU (1) AU2010317668C1 (enExample)
BR (1) BR112012011224A2 (enExample)
CA (1) CA2780704C (enExample)
CO (1) CO6551745A2 (enExample)
EC (2) ECSP12011892A (enExample)
GB (1) GB0919893D0 (enExample)
IL (1) IL219769A0 (enExample)
MX (1) MX2012005538A (enExample)
NZ (1) NZ599957A (enExample)
PE (1) PE20121472A1 (enExample)
PH (1) PH12012500955A1 (enExample)
RU (1) RU2587329C2 (enExample)
SG (1) SG10201407496SA (enExample)
UA (1) UA105940C2 (enExample)
WO (1) WO2011058374A1 (enExample)
ZA (1) ZA201204247B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10016437B2 (en) 2009-06-16 2018-07-10 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB201111485D0 (en) * 2011-07-05 2011-08-17 Biocopea Ltd Drug composition and its use in therapy
US9308211B2 (en) 2009-06-16 2016-04-12 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
US9314465B2 (en) 2009-06-16 2016-04-19 Infirst Healthcare Limited Drug combinations and uses in treating a coughing condition
GB0910375D0 (en) 2009-06-16 2009-07-29 Biocopea Ltd Drug composition and its use in therapy

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989003213A1 (fr) * 1987-10-08 1989-04-20 Andor Bilas Melange de substances pour stabiliser le metabolisme
CN1130354A (zh) * 1993-09-07 1996-09-04 普罗克特和廿保尔公司 含有丙酸类非甾体消炎药氨基酸盐和减充血药、祛痰药、抗组胺药和镇咳药中至少一种的组合物
CN1251039A (zh) * 1997-03-26 2000-04-19 代热·科尔博尼兹 镇咳组合物
WO2000030715A1 (en) * 1998-11-25 2000-06-02 Chinoin Gyógyszer És Vegyészeti Composition containing an analgesic and a xanthine or a xanthine derivative
WO2008002514A2 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6608073B1 (en) * 1998-10-14 2003-08-19 New Millennium Pharmaceutical Research, Inc. Intranasal codeine for the rapid suppression of cough and rapid relief of pain
ES2528384T3 (es) * 2001-12-12 2015-02-09 The Government Of The United States Of America, As Represented By The Secretary Department Of Healt Métodos de utilización de inhibidores del receptor de adenosina para potenciar la respuesta inmunitaria y la inflamación
AU2004216550B2 (en) * 2003-02-28 2010-06-03 Ym Biosciences Inc. Opioid delivery system
CN1593451A (zh) * 2003-09-12 2005-03-16 杨喜鸿 促进男性勃起的外用药物
JPWO2006064780A1 (ja) * 2004-12-14 2008-06-12 塩野義製薬株式会社 便秘治療剤
KR20080009994A (ko) * 2006-07-25 2008-01-30 안국약품 주식회사 기침 치료용 조성물

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989003213A1 (fr) * 1987-10-08 1989-04-20 Andor Bilas Melange de substances pour stabiliser le metabolisme
CN1130354A (zh) * 1993-09-07 1996-09-04 普罗克特和廿保尔公司 含有丙酸类非甾体消炎药氨基酸盐和减充血药、祛痰药、抗组胺药和镇咳药中至少一种的组合物
CN1251039A (zh) * 1997-03-26 2000-04-19 代热·科尔博尼兹 镇咳组合物
WO2000030715A1 (en) * 1998-11-25 2000-06-02 Chinoin Gyógyszer És Vegyészeti Composition containing an analgesic and a xanthine or a xanthine derivative
WO2008002514A2 (en) * 2006-06-26 2008-01-03 Levine Brian M Combination cough treatment compounds and method of treating common coughs

Also Published As

Publication number Publication date
CA2780704A1 (en) 2011-05-19
ZA201204247B (en) 2013-02-27
EP2498776A1 (en) 2012-09-19
CA2780704C (en) 2018-07-17
AU2010317668C1 (en) 2016-02-11
IL219769A0 (en) 2012-07-31
RU2012124063A (ru) 2013-12-20
CN102740853A (zh) 2012-10-17
PE20121472A1 (es) 2012-11-30
JP2013510842A (ja) 2013-03-28
RU2587329C2 (ru) 2016-06-20
UA105940C2 (uk) 2014-07-10
GB0919893D0 (en) 2009-12-30
WO2011058374A1 (en) 2011-05-19
SG10201407496SA (en) 2015-02-27
ECSP12011892A (es) 2012-09-28
CO6551745A2 (es) 2012-10-31
NZ599957A (en) 2014-05-30
AU2010317668A1 (en) 2012-06-07
JP2016041748A (ja) 2016-03-31
BR112012011224A2 (pt) 2017-03-01
AU2010317668B2 (en) 2015-01-22
ECSP12011893A (es) 2012-10-30
PH12012500955A1 (en) 2013-01-07
MX2012005538A (es) 2012-09-28

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: THE FIRST MEDICAL HEALTH CARE CO., LTD.

Free format text: FORMER OWNER: RUISI PIKOU PIYA CO., LTD.

Effective date: 20141127

Owner name: RUISI PIKOU PIYA CO., LTD.

Free format text: FORMER OWNER: BIOCOPEA LTD.

Effective date: 20141127

C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20141127

Address after: London, England

Applicant after: InFirst Healthcare Ltd.

Address before: Dublin, Ireland

Applicant before: Reyes Leather Co.,Ltd. Ethiopia Lancome

Effective date of registration: 20141127

Address after: Dublin, Ireland

Applicant after: Reyes Leather Co.,Ltd. Ethiopia Lancome

Address before: London, England

Applicant before: BIOCOPEA Ltd.

C14 Grant of patent or utility model
GR01 Patent grant
CP01 Change in the name or title of a patent holder
CP01 Change in the name or title of a patent holder

Address after: London, England

Patentee after: BIOCOPEA LTD.

Address before: London, England

Patentee before: InFirst Healthcare Ltd.

CF01 Termination of patent right due to non-payment of annual fee
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150408

Termination date: 20181112