Radix Paeoniae Alba Chinese medicine preparation and the preparation method for the treatment of hypochondriac pain
Technical field
The invention belongs to the field of Chinese medicines, relate in particular to a kind of Radix Paeoniae Alba Chinese medicine preparation and preparation method that is used for the treatment of hypochondriac pain.
Background technology
Hypochondriac pain refers to a side or the both sides pain over the hypochondriac region, is a kind of blindness disease of patient.Because liver occupies under the side of body, the gallbladder being attached to the liver, the channel course of liver and gall is in two sides of body, therefore the outbreak of hypochondriac pain is how relevant to hepatobiliary disease.As " a Ling Shu Miraculous Pivot or Divine Axis five pathogenic factors piece of writing " is upper, says " heresy is just liver, in two sides of body bitterly "." opinion when Plain Questions is hidden the device method " also said: " hepatitis person, bilateral hypochondriac pain referring to the lateral-lower abdomen." hypochondriac pain is symptom common in liver and gall diseases, it is clinical that many diseases are arranged is all to judge that according to hypochondriac pain it is hepatopathy or is the disease relevant with liver and gall.The disease that the side of body flank one or both sides pain of take is main manifestations.Liver occupies under the side of body, and its passages through which vital energy circulates is distributed in two sides of body, the gallbladder being attached to the liver, and its arteries and veins also follows in the side of body, so hypochondriac pain is how relevant with liver and gall diseases.All depressed emotions, depression of liver-QI, or surfeit delicious food, be addicted to drink immoderate, or weakness due to chronic disease, melancholy,anxiety and overstrain, or tumbling down wound etc. all can cause hypochondriac pain.When dialectical, should first divide the QI and blood deficiency and excess, general stagnation of QI person mostly is distending pain, and the sore spot migration is indefinite.The blood stasis person mostly is twinge, localized pain.The deficiency syndrome hypochondriac pain has a dull ache more, the many pain bursts of excess syndrome hypochondriac pain, and the pain gesture is more acute.Clinical common following pattern of syndrome: 1. liver qi stagnation type hypochondriac pain: card is shown in the hypochondriac pain distending pain, and it is indefinite to walk to alter, uncomfortable in chest indigestion and loss of appetite, the thin fur stringy pulse; 2. qi stagnation and blood stasis type hypochondriac pain: card is shown in stitch in the side, does not fixingly move, and under side of body rib, maybe can touch caking, and purplish tongue is dark, deep and hesitant pulse; 3. liver gallbladder damp-heat type hypochondriac pain: card is shown in that hypochondriac pain is uncomfortable in chest, and bitter taste is indigestion and loss of appetite, or the yellowish urine fever of the body, yellow and greasy fur, wiry and frequent pulse; 4. deficiecny of liver-YIN type hypochondriac pain: card is shown in that hypochondriac pain is indistinct, and xerostomia is vexed, has a dizzy spell, and the few tongue of red tongue, stringy and thready pulse or number; Though the hypochondriac pain cause of disease have Exogenous and internal injuries minute, more common with hypochondrium pain with internal injury, the hypochondriac pain paathogenic factor has that depression of liver-QI, blood stasis are at a stop, dampness-heat in the liver and gallbladder, deficiecny of liver-YIN etc.Its pathological changes is mainly in liver and gall.Its etiology and pathogenesis, except stagnation of QI blood stasis, outside straight impairing the liver gallbladder, simultaneously relevant with taste, kidney.Aspect disease, there is void that reality is arranged, and take excess syndrome as common.Excess syndrome be take the stagnation of QI, blood stasis, damp and hot as main, and the three be take again the stagnation of QI as first.Deficiency syndrome cloudy anemia damage, the liver failing to be nourished of belonging to more.In addition, excess syndrome with the passing of time, the heat-transformation impairment of YIN, the hepatic and renal YIN deficiency, deficiency and excess also can occur and see.The hypochondriac pain clinical syndrome differentiation, when take QI and blood as main.On the whole distending pain belongs to the stagnation of QI more, and pain is migration without fixed; Twinge belongs to blood stasis more, and localized pain; Dull pain belongs to the deficiency of YIN more, and its pain is continuous; Damp and hot hypochondriac pain, mainly with sharp ache, and with the bitter taste yellow fur.Treatment be take and led to as main, excess syndrome adopt regulates the flow of vital energy, the methods such as blood stasis dispelling, heat clearing away, dampness removing, the deficiency syndrome nourishing yin for softening liver, for controlling, can suitably add the product of regulating the flow of vital energy, to unclog and readjust irritability, raising curative effect, determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs.Western modern medicine treatment hypochondriac pain is cured the symptoms, not the disease, and expenses for medicine is high, easily have side effects large, Chinese medicine has treating both the principal and secondary aspects of a disease, does not recur the advantage of effecting a permanent cure and digging up the roots after healing, adopt the means of Chinese medicine to treat the costalgia disease, giving consideration to both the incidental and fundamental, be a channel extremely leaved for development, and there is its original effect the treatment aspect.
Summary of the invention
The purpose of this invention is to provide a kind of advantages of perfect compatibility that has, have no side effect, curative effect is treated Radix Paeoniae Alba Chinese medicine preparation and the preparation method of hypochondriac pain reliably.
For achieving the above object, the present invention is achieved by the following technical solutions:
The Radix Paeoniae Alba Chinese medicine preparation for the treatment of hypochondriac pain, by the raw material of Chinese medicine of following weight portion, made:
Radix Paeoniae Alba 100-300 part, Radix Bupleuri 80-220 part, Fructus Aurantii 80-220 part, Rhizoma Cyperi 80-220 part, Radix Aucklandiae 80-220 part, Semen Litchi 80-220 part, Fructus Citri 80-220 part.
The Radix Paeoniae Alba Chinese medicine preparation of described treatment hypochondriac pain, by the raw material of Chinese medicine of following weight portion, made:
200 parts of the Radix Paeoniae Albas, 150 parts of Radix Bupleuri, 150 parts of Fructus Aurantiis, 150 parts of Rhizoma Cyperis, 150 parts of the Radix Aucklandiae, 150 parts of Semen Litchis, 150 parts of Fructus Citris.
The preparation method of the Radix Paeoniae Alba Chinese medicine preparation of described treatment hypochondriac pain, its preparation method is:
Take in proportion 200 parts of the raw material of Chinese medicine Radix Paeoniae Albas, 150 parts of Radix Bupleuri, 150 parts of Fructus Aurantiis, 150 parts of Rhizoma Cyperis, 150 parts of the Radix Aucklandiae, 150 parts of Semen Litchis, 150 parts of Fructus Citris, cleaning is dried, be ground into granule, soak 1.5 hours, then decoct with water twice, add for the first time the water of 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filtration, add for the second time the water of 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Usage and consumption: oral Chinese medicine preparation of the present invention, each 180ml, every day 2 times, half an hour, 15 days be 1 course for the treatment of after meal.
The pharmacological action of crude drug of the present invention is as follows, the Radix Paeoniae Alba: bitter, acid, be slightly cold, return liver, spleen channel, the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain, suppressing liver-YANG; Radix Bupleuri: bitter, hot, be slightly cold, GUIXIN envelope, liver, gallbladder, tri-jiao channel, evacuate bring down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy; Fructus Aurantii: bitter, acid, be slightly cold, return lung, spleen, liver, stomach, large intestine channel, septum pectorale feeling of fullness, distending pain over the hypochondrium, distension and fullness in the abdomen; Rhizoma Cyperi: hot, micro-hardship, micro-sweet, flat, return liver, tri-jiao channel, depressed liver-energy dispersing and QI regulating, menstruction regulating and pain relieving; The Radix Aucklandiae: hot, bitter, temperature, return spleen, stomach, liver, large intestine channel, can rise can fall, a surname is stagnant in promoting the circulation of QI to relieve pain, tune; Semen Litchi: sweet, puckery, warm, return liver, stomach warp, promoting QI to circulate and dispersing the agglomeration of the pathogens, dispersing cold for relieving pain, eliminating stagnation row are stagnant; Fructus Citri: temperature, hot, bitter, sour enters Liver Channel, spleen channel, lung meridian, dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, preventing phlegm from forming and stopping coughing; All medicines are the merit of long memorial liver and qi altogether, Chinese medicine preparation of the present invention has remarkable therapeutic effect to liver qi stagnation type hypochondriac pain patient, can alleviate rapidly side of body distending pain, it is indefinite to walk to alter, every because feelings will increases and decreases, the symptom of sensation of oppression over the chest with shortness of breath, this preparation has no side effect, therapeutic effect is remarkable, has fundamentally removed patient's misery.
The specific embodiment
EXAMPLE l
Raw material of Chinese medicine: 200 parts of the Radix Paeoniae Albas, 150 parts of Radix Bupleuri, 150 parts of Fructus Aurantiis, 150 parts of Rhizoma Cyperis, 150 parts of the Radix Aucklandiae, 150 parts of Semen Litchis, 150 parts of Fructus Citris.
Preparation method: take in proportion 200 parts of the raw material of Chinese medicine Radix Paeoniae Albas, 150 parts of Radix Bupleuri, 150 parts of Fructus Aurantiis, 150 parts of Rhizoma Cyperis, 150 parts of the Radix Aucklandiae, 150 parts of Semen Litchis, 150 parts of Fructus Citris, cleaning is dried, be ground into granule, soak 1.5 hours, then decoct with water twice, add for the first time the water of 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filtration, add for the second time the water of 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Embodiment 2
Raw material of Chinese medicine: 300 parts of the Radix Paeoniae Albas, 220 parts of Radix Bupleuri, 220 parts of Fructus Aurantiis, 220 parts of Rhizoma Cyperis, 220 parts of the Radix Aucklandiae, 220 parts of Semen Litchis, 220 parts of Fructus Citris.
Preparation method: take in proportion 300 parts of the raw material of Chinese medicine Radix Paeoniae Albas, 220 parts of Radix Bupleuri, 220 parts of Fructus Aurantiis, 220 parts of Rhizoma Cyperis, 220 parts of the Radix Aucklandiae, 220 parts of Semen Litchis, 220 parts of Fructus Citris, cleaning is dried, be ground into granule, soak 1.5 hours, then decoct with water twice, add for the first time the water of 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filtration, add for the second time the water of 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Embodiment 3
Raw material of Chinese medicine: 100 parts of the Radix Paeoniae Albas, 80 parts of Radix Bupleuri, 80 parts of Fructus Aurantiis, 80 parts of Rhizoma Cyperis, 80 parts of the Radix Aucklandiae, 80 parts of Semen Litchis, 80 parts of Fructus Citris.
Preparation method: take in proportion 100 parts of the raw material of Chinese medicine Radix Paeoniae Albas, 80 parts of Radix Bupleuri, 80 parts of Fructus Aurantiis, 80 parts of Rhizoma Cyperis, 80 parts of the Radix Aucklandiae, 80 parts of Semen Litchis, 80 parts of Fructus Citris, cleaning is dried, be ground into granule, soak 1.5 hours, then decoct with water twice, add for the first time the water of 8 times of amounts of crude drug, after intense fire is fried boiling, slow fire boiling 1-2 hour again, get decocting liquid, filtration, add for the second time the water of 6 times of amounts of crude drug, decoct 0.5-1.5 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 180ml, high temperature sterilize, pack and get final product.
Embodiment 4
Clinical trial
1) physical data:
Adopt Chinese medicine preparation of the present invention to treat altogether in 36 routine patients, male 23 examples, in age 30-67 year, average 48.5 years old, the course of disease was the shortest 1 month, the longest 5 months; Female's 13 examples, in age 29-65 year, average 47 years old, the course of disease was the shortest 1 month, the longest 4 months.
2) diagnostic criteria: primary symptom: side of body distending pain, it is indefinite to walk to alter, every because feelings will increases and decreases, sensation of oppression over the chest with shortness of breath, heating installation is done frequently, the thin fur stringy pulse.
3) Therapeutic Method: the oral embodiment of the present invention 1 Chinese medicine decoction, each 180ml, every day 2 times, half an hour, 15 days be 1 course for the treatment of after meal, is used in conjunction drug withdrawal after 2 courses for the treatment of, judges curative effect comprehensively, follows up a case by regular visits to the statistics recurrence after 3 months.
4) the standard of curative effect evaluation:
Cure: sign and symptom are improved fully, happy, in high spirits.
Produce effects: sign and symptom are significantly improved, happy, and spirit is fine.
Effectively: sign and symptom change, and random thoughts slightly have discomfort, but can accept.
Invalid: sign is without change, and symptom is as front.
5) therapeutic outcome: in the routine case of patient 36, through 2 course of therapy, wherein cure 30 examples, produce effects 2 examples, effective 4 examples, invalid 0 example, total effective rate 100%, the course for the treatment of is the shortest 30 days, the longest 60 days, follows up a case by regular visits to and within 1 year, has no recurrence.
Embodiment 5
Model case: often certain, 55 years old, the female, side of body distending pain, it is indefinite to walk to alter, every because feelings will increases and decreases, sensation of oppression over the chest with shortness of breath, heating installation is done frequently, the thin fur stringy pulse, the Chinese medicine preparation of taking embodiment 1 takes effect 1 course for the treatment of, cure 3 courses for the treatment of.
Embodiment 6
Model case: Ma, 61 years old, the man, side of body distending pain, it is indefinite to walk to alter, every because feelings will increases and decreases, sensation of oppression over the chest with shortness of breath, heating installation is done frequently, the thin fur stringy pulse, the Chinese medicine preparation of taking embodiment 1 takes effect 1 course for the treatment of, and cure 3 courses for the treatment of.