CN102711787A - 用于治疗或预防a型流感病毒感染的par1拮抗剂 - Google Patents
用于治疗或预防a型流感病毒感染的par1拮抗剂 Download PDFInfo
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09306098A EP2335717A1 (en) | 2009-11-16 | 2009-11-16 | PAR-1 antagonists for use in the treatment or prevention of influenza virus type a infections |
| EP09306098.6 | 2009-11-16 | ||
| PCT/EP2010/067516 WO2011058183A1 (en) | 2009-11-16 | 2010-11-15 | Par-1 antagonists for use in the treatment or prevention of influenza virus type a infections |
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| EP (2) | EP2335717A1 (https=) |
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| KR (1) | KR20120098696A (https=) |
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| AU (1) | AU2010317917B2 (https=) |
| CA (1) | CA2780835A1 (https=) |
| WO (1) | WO2011058183A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116999558A (zh) * | 2023-10-07 | 2023-11-07 | 中国人民解放军军事科学院军事医学研究院 | Par1作为用于治疗或者抑制埃博拉病毒的靶点的应用 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140378502A1 (en) * | 2011-05-12 | 2014-12-25 | UNIVERSITé LAVAL | Par1 Inhibitors for Use in the Treatment or Prevention of Paramyxoviridae Infections |
| WO2013070256A2 (en) * | 2011-11-07 | 2013-05-16 | The Scripps Research Institute | Protease activated receptor-1 (par1) derived cytoprotective polypeptides and related methods |
| JP2016520570A (ja) * | 2013-04-22 | 2016-07-14 | アンスティテュ ナシオナル ドゥ ラ ルシェルシュ アグロノミックＩｎｓｔｉｔｕｔ Ｎａｔｉｏｎａｌ Ｄｅ Ｌａ Ｒｅｃｈｅｒｃｈｅ Ａｇｒｏｎｏｍｉｑｕｅ | Ａ型インフルエンザウイルス感染の治療又は予防に使用するためのｐａｒ−４アンタゴニスト |
| HK1225386A1 (zh) | 2013-09-25 | 2017-09-08 | 沃泰克斯药物股份有限公司 | 用作par-2信號傳導途徑抑制劑的咪唑並噠嗪類 |
| WO2015124570A1 (en) * | 2014-02-18 | 2015-08-27 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical composition for the treatment of influenza a virus infection |
| CN107106632A (zh) * | 2014-12-29 | 2017-08-29 | 中央研究院 | 一种治疗a型流感病毒感染的方法 |
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| WO1993018141A1 (en) * | 1992-03-02 | 1993-09-16 | Biogen, Inc. | Thrombin receptor antagonists |
| US5866681A (en) * | 1992-07-30 | 1999-02-02 | Cor Therapeutics, Inc. | Thrombin receptor antagonists |
| WO2001000659A1 (en) * | 1999-06-29 | 2001-01-04 | Ortho-Mcneil Pharmaceutical, Inc. | Benzimidazolone peptidomimetics as thrombin receptor antagonists |
| US20080097385A1 (en) * | 2004-12-22 | 2008-04-24 | Jakob Vinten-Johansen | Therapeutic Adjuncts to Enhance the Organ Protective Effects of Postconditioning |
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| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US5688768A (en) | 1991-02-19 | 1997-11-18 | Cor Therapeutics, Inc. | Recombinant thrombin receptor and related pharmaceuticals |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| US6017890A (en) | 1998-02-19 | 2000-01-25 | Ortho-Mcneil Pharmaceutical, Inc. | Azole peptidomimetics as thrombin receptor antagonists |
| GB0213286D0 (en) | 2002-06-10 | 2002-07-24 | Univ Edinburgh | Par-2-Activating peptide derivative and pharmaceutical composition using the same |
| US8563511B2 (en) * | 2004-10-06 | 2013-10-22 | University Of Rochester | Treatment of pulmonary hypertension using an agent that inhibits a tissue factor pathway |
| US20080318960A1 (en) | 2005-05-26 | 2008-12-25 | Ethan Burstein | PAR2-modulating compounds and their use |
| US20070123508A1 (en) | 2005-05-27 | 2007-05-31 | Roger Olsson | PAR2-modulating compounds and their use |
| SI2242740T1 (sl) * | 2008-02-05 | 2013-03-29 | Sanofi | SF5-derivati kot PAR1 inhibitorji, njihova priprava in uporaba kot zdravila |
| EP2427205A2 (en) | 2009-05-04 | 2012-03-14 | INSERM - Institut National de la Santé et de la Recherche Médicale | Par2 agonists for use in the treatment or prevention of influenza virus type a infections |
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- 2009-11-16 EP EP09306098A patent/EP2335717A1/en not_active Withdrawn
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- 2010-11-15 CN CN2010800612436A patent/CN102711787A/zh active Pending
- 2010-11-15 WO PCT/EP2010/067516 patent/WO2011058183A1/en not_active Ceased
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- 2010-11-15 AU AU2010317917A patent/AU2010317917B2/en not_active Ceased
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2014
- 2014-06-23 US US14/311,870 patent/US20140308296A1/en not_active Abandoned
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| WO1993018141A1 (en) * | 1992-03-02 | 1993-09-16 | Biogen, Inc. | Thrombin receptor antagonists |
| US5866681A (en) * | 1992-07-30 | 1999-02-02 | Cor Therapeutics, Inc. | Thrombin receptor antagonists |
| WO2001000659A1 (en) * | 1999-06-29 | 2001-01-04 | Ortho-Mcneil Pharmaceutical, Inc. | Benzimidazolone peptidomimetics as thrombin receptor antagonists |
| US20080097385A1 (en) * | 2004-12-22 | 2008-04-24 | Jakob Vinten-Johansen | Therapeutic Adjuncts to Enhance the Organ Protective Effects of Postconditioning |
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| ATSUFUMI KAWABATA等: "Evaluation of Proteinase-Activated Receptor-1 (PAR1) Agonists and Antagonists Using a Cultured Cell Receptor Desensitization Assay: Activation of PAR2 by PAR1-Targeted Ligands", 《THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS》, vol. 288, no. 1, 31 December 1999 (1999-12-31), pages 358 - 370, XP000946514 * |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116999558A (zh) * | 2023-10-07 | 2023-11-07 | 中国人民解放军军事科学院军事医学研究院 | Par1作为用于治疗或者抑制埃博拉病毒的靶点的应用 |
| CN116999558B (zh) * | 2023-10-07 | 2024-01-02 | 中国人民解放军军事科学院军事医学研究院 | Par1作为用于治疗或者抑制埃博拉病毒的靶点的应用 |
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| EP2335717A1 (en) | 2011-06-22 |
| AU2010317917A1 (en) | 2012-06-07 |
| WO2011058183A1 (en) | 2011-05-19 |
| EP2501395A1 (en) | 2012-09-26 |
| US20140308296A1 (en) | 2014-10-16 |
| US20120213802A1 (en) | 2012-08-23 |
| JP2013510832A (ja) | 2013-03-28 |
| AU2010317917B2 (en) | 2014-07-24 |
| KR20120098696A (ko) | 2012-09-05 |
| CA2780835A1 (en) | 2011-05-19 |
| US8802623B2 (en) | 2014-08-12 |
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