CN102697943A - Skin disinfectant - Google Patents
Skin disinfectant Download PDFInfo
- Publication number
- CN102697943A CN102697943A CN2012102068870A CN201210206887A CN102697943A CN 102697943 A CN102697943 A CN 102697943A CN 2012102068870 A CN2012102068870 A CN 2012102068870A CN 201210206887 A CN201210206887 A CN 201210206887A CN 102697943 A CN102697943 A CN 102697943A
- Authority
- CN
- China
- Prior art keywords
- parts
- fructus
- skin disinfectant
- root
- herba
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000645 desinfectant Substances 0.000 title abstract description 10
- 239000003814 drug Substances 0.000 claims abstract description 14
- 230000002421 anti-septic effect Effects 0.000 claims description 9
- 229940079593 drug Drugs 0.000 claims description 6
- UAJTZZNRJCKXJN-UHFFFAOYSA-M sodium;2-dodecoxy-2-oxoethanesulfonate Chemical compound [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O UAJTZZNRJCKXJN-UHFFFAOYSA-M 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 6
- 230000001954 sterilising effect Effects 0.000 abstract description 3
- MFYSUUPKMDJYPF-UHFFFAOYSA-N 2-[(4-methyl-2-nitrophenyl)diazenyl]-3-oxo-n-phenylbutanamide Chemical compound C=1C=CC=CC=1NC(=O)C(C(=O)C)N=NC1=CC=C(C)C=C1[N+]([O-])=O MFYSUUPKMDJYPF-UHFFFAOYSA-N 0.000 abstract 1
- 241000758794 Asarum Species 0.000 abstract 1
- 241000892667 Cnidium silaifolium Species 0.000 abstract 1
- 244000247747 Coptis groenlandica Species 0.000 abstract 1
- 235000002991 Coptis groenlandica Nutrition 0.000 abstract 1
- 241000576429 Forsythia suspensa Species 0.000 abstract 1
- 240000001972 Gardenia jasminoides Species 0.000 abstract 1
- 235000013717 Houttuynia Nutrition 0.000 abstract 1
- 240000000691 Houttuynia cordata Species 0.000 abstract 1
- 235000006679 Mentha X verticillata Nutrition 0.000 abstract 1
- 235000002899 Mentha suaveolens Nutrition 0.000 abstract 1
- 235000001636 Mentha x rotundifolia Nutrition 0.000 abstract 1
- 235000003805 Musa ABB Group Nutrition 0.000 abstract 1
- 240000008790 Musa x paradisiaca Species 0.000 abstract 1
- 235000015266 Plantago major Nutrition 0.000 abstract 1
- 240000004534 Scutellaria baicalensis Species 0.000 abstract 1
- 235000017089 Scutellaria baicalensis Nutrition 0.000 abstract 1
- 241000219784 Sophora Species 0.000 abstract 1
- 230000007797 corrosion Effects 0.000 abstract 1
- 238000005260 corrosion Methods 0.000 abstract 1
- 230000000249 desinfective effect Effects 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 30
- 239000000706 filtrate Substances 0.000 description 4
- 239000002244 precipitate Substances 0.000 description 4
- 238000004659 sterilization and disinfection Methods 0.000 description 4
- 239000006228 supernatant Substances 0.000 description 4
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 230000028327 secretion Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 description 1
- 206010000097 Abdominal tenderness Diseases 0.000 description 1
- 206010059313 Anogenital warts Diseases 0.000 description 1
- 208000004926 Bacterial Vaginosis Diseases 0.000 description 1
- 206010012442 Dermatitis contact Diseases 0.000 description 1
- 229920000153 Povidone-iodine Polymers 0.000 description 1
- 208000008350 Pruritus Vulvae Diseases 0.000 description 1
- 206010056530 Vulvovaginal pruritus Diseases 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 208000010247 contact dermatitis Diseases 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- -1 geramine Chemical compound 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 239000012286 potassium permanganate Substances 0.000 description 1
- 229960001621 povidone-iodine Drugs 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 239000011550 stock solution Substances 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a skin disinfectant, which is prepared from the following bulk pharmaceuticals in parts by weight: 5-10 parts of belvedere fruit, 10-20 parts of baikal skullcap root, 5-15 parts of coptis root, 2-10 parts of heartleaf houttuynia herb, 15-25 parts of weeping forsythia, 5-10 parts of plantain herb, 5-10 parts of fructus gardenia, 5-10 parts of lightyellow sophora root, 5-10 parts of selinum japenious seed and 5-15 parts of mint. The skin disinfectant provided by the invention is a pure Chinese medicinal preparation, has no toxic and side effects on human bodies, is corrosion-resistant and environment-friendly, has a good disinfecting effect and strong sterilizing power, and is worthy of clinical popularization and application.
Description
Technical field
The present invention relates to a kind of disinfectant, particularly relate to a kind of skin antiseptic that is prepared from Chinese herbal medicine.
Background technology
The kind of existing skin antiseptic is a lot, mainly contains the disinfectant of chemical classes and the disinfectant of Chinese medicine class, and the disinfectant of the chemical classes that is widely used now has ethanol, povidone iodine, hydrogen peroxide, geramine, boric acid, potassium permanganate etc.; But the zest of these disinfectant is big; Be easy to cause the permanent damage of skin, and Chinese medicine antiseptic because of its action temperature with, side effect is little; Received people's attention gradually, but existing Chinese medicine antiseptic but rarely has the product of determined curative effect.
Summary of the invention
In order to solve the problems of the technologies described above, the invention provides a kind of skin antiseptic, it is pure Chinese medicine product, zest is little, has no side effect, and evident in efficacy.
Technical scheme of the present invention is following:
A kind of skin antiseptic is prepared from the crude drug of following weight parts: Fructus Kochiae 5-10, Radix Scutellariae 10-20, Rhizoma Coptidis 5-15, Herba Houttuyniae 2-10, Fructus Forsythiae 15-25, Herba Plantaginis 5-10, Fructus Gardeniae 5-10, Radix Sophorae Flavescentis 5-10, Fructus Cnidii 5-10, Herba Menthae 5-15.
Method for preparing: get above each flavor, the decocting that adds 10 times, 8 times amounts boils each 2 hours 2 times; Merging filtrate, being concentrated into relative density is 1.15-1.25, adds ethanol; Making determining alcohol is 60-75%, and precipitate with ethanol 24 hours is got supernatant and reclaimed ethanol; Make its concentration for containing crude drug 1.5～2.5 grams per milliliters, subsequent use.
The present invention can also be prepared into spray or aerosol.
Effect experiment
Get skin antiseptic of the present invention, skin surface carried out disinfection, survey the total plate count of its sterilization front and back, survey 10 groups altogether, experimental data such as table 1:
Table 1 disinfectant disinfection test result
| Sequence number | Clump count (cfu/cm before the experiment 2） | Test back clump count (cfu/cm 2） | Killing rate (%) |
| 1 | 11.5 | 0.5 | 95.7 |
| 2 | 48.7 | 2.4 | 95.1 |
| 3 | 32.1 | 0.4 | 98.8 |
| 4 | 5.3 | 0.1 | 98.1 |
| 5 | 71.8 | 1.4 | 98.1 |
| 6 | 19.6 | 0.8 | 95.9 |
| 7 | 24.9 | 0.7 | 97.2 |
| 8 | 39.8 | 0.6 | 98.5 |
| 9 | 43.8 | 0.8 | 98.2 |
| 10 | 4.9 | 0.0 | 100% |
Can find out that from above data the bactericidal effect of disinfectant of the present invention is remarkable.
Air sanitizer provided by the invention is a pure Chinese medicinal preparation, to the human non-toxic side effect, and non-corrosiveness, free from environmental pollution, and also its Disinfection Effect is good, and sterilizing power is strong, is worth clinical application.
The specific embodiment
Below in conjunction with embodiment the present invention is done further explanation.
Embodiment 1
Get Fructus Kochiae 50g, Radix Scutellariae 100g, Rhizoma Coptidis 50g, Herba Houttuyniae 20g, Fructus Forsythiae 150g, Herba Plantaginis 50g, Fructus Gardeniae 50g, Radix Sophorae Flavescentis 50g, Fructus Cnidii 50g, Herba Menthae 50g, the decocting that adds 10 times, 8 times amounts boils each 2 hours 2 times; Merging filtrate, being concentrated into relative density is 1.20, adds ethanol; Making determining alcohol is 70%, and precipitate with ethanol 24 hours is got supernatant and reclaimed ethanol; Make its concentration for containing crude drug 2.0 grams per milliliters, subsequent use.
Embodiment 2
Get Fructus Kochiae 100g, Radix Scutellariae 200g, Rhizoma Coptidis 150g, Herba Houttuyniae 100g, Fructus Forsythiae 250g, Herba Plantaginis 100g, Fructus Gardeniae 100g, Radix Sophorae Flavescentis 100g, Fructus Cnidii 100g, Herba Menthae 150g, the decocting that adds 10 times, 8 times amounts boils each 2 hours 2 times; Merging filtrate, being concentrated into relative density is 1.15, adds ethanol; Making determining alcohol is 75%, and precipitate with ethanol 24 hours is got supernatant and reclaimed ethanol; Make its concentration for containing crude drug 2.0 grams per milliliters, subsequent use.
Embodiment 3
Get Fructus Kochiae 80g, Radix Scutellariae 150g, Rhizoma Coptidis 100g, Herba Houttuyniae 60g, Fructus Forsythiae 200g, Herba Plantaginis 80g, Fructus Gardeniae 80g, Radix Sophorae Flavescentis 80g, Fructus Cnidii 80g, Herba Menthae 100g, the decocting that adds 10 times, 8 times amounts boils each 2 hours 2 times; Merging filtrate, being concentrated into relative density is 1.25, adds ethanol; Making determining alcohol is 75%, and precipitate with ethanol 24 hours is got supernatant and reclaimed ethanol; Make its concentration for containing crude drug 2.0 grams per milliliters, subsequent use.
Model case
Case 1
Zhang, the man is diagnosed as when examining under the left side and tucks in contact dermatitis, advises it to use medicine stock solution washout of the present invention, uses first day sx, recovery from illness in the 3rd day, after treatment two days does not have recurrence subsequently.
Case 2
Neat certain, the woman, pruritus vulvae when examining, secretions is many, abdominal tenderness has abnormal flavour, is diagnosed as bacterial vaginitis after the check, advises it to soak into medicine of the present invention with gauze and puts into vaginal treatment, treat second day sx, secretions was normal on 1, the abnormal flavour disappearance.
Case 3
Bian, the man, the condyloma acuminatum treatment does not more change my institute over to January, advises it with medicine washout of the present invention, and wound surface on the 3rd begins to take a turn for the better, and wound surface healed basically on 10, no sense of discomfort, wound surface recovery from illness on the 15th is followed up a case by regular visits to after 1 month and is not had recurrence.
Claims (1)
1. skin antiseptic; It is characterized in that, be prepared from the crude drug of following weight parts: Fructus Kochiae 5-10, Radix Scutellariae 10-20, Rhizoma Coptidis 5-15, Herba Houttuyniae 2-10, Fructus Forsythiae 15-25, Herba Plantaginis 5-10, Fructus Gardeniae 5-10, Radix Sophorae Flavescentis 5-10, Fructus Cnidii 5-10, Herba Menthae 5-15.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102068870A CN102697943B (en) | 2012-06-21 | 2012-06-21 | Skin disinfectant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2012102068870A CN102697943B (en) | 2012-06-21 | 2012-06-21 | Skin disinfectant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102697943A true CN102697943A (en) | 2012-10-03 |
| CN102697943B CN102697943B (en) | 2013-11-13 |
Family
ID=46891190
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012102068870A Active CN102697943B (en) | 2012-06-21 | 2012-06-21 | Skin disinfectant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102697943B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107970307A (en) * | 2016-10-21 | 2018-05-01 | 鼎正动物药业（天津）有限公司 | A kind of Chinese medicine antiseptic for preventing aquaculture bacteriosis and preparation method thereof |
| CN115300426A (en) * | 2022-08-09 | 2022-11-08 | 深圳青春一九美业管理有限公司 | Lysozyme skin disinfectant with skin protection function and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5411733A (en) * | 1992-04-27 | 1995-05-02 | Hozumi; Toyoharu | Antiviral agent containing crude drug |
| CN1116091A (en) * | 1994-08-05 | 1996-02-07 | 宋凯 | Bath liquid for disinfection nursing |
| KR20030011731A (en) * | 2002-11-25 | 2003-02-11 | 미즈코리아 주식회사 | Antibiotic and cosmetic compositions containing herb medicines |
| CN102048675A (en) * | 2010-12-15 | 2011-05-11 | 郑高育 | Fragrant grass vagina cleaning liquid and preparation process thereof |
-
2012
- 2012-06-21 CN CN2012102068870A patent/CN102697943B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5411733A (en) * | 1992-04-27 | 1995-05-02 | Hozumi; Toyoharu | Antiviral agent containing crude drug |
| CN1116091A (en) * | 1994-08-05 | 1996-02-07 | 宋凯 | Bath liquid for disinfection nursing |
| KR20030011731A (en) * | 2002-11-25 | 2003-02-11 | 미즈코리아 주식회사 | Antibiotic and cosmetic compositions containing herb medicines |
| CN102048675A (en) * | 2010-12-15 | 2011-05-11 | 郑高育 | Fragrant grass vagina cleaning liquid and preparation process thereof |
Non-Patent Citations (1)
| Title |
|---|
| 邱志慧等: "中药外用治疗女性外阴炎疗效观察", 《洛阳医专学报》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107970307A (en) * | 2016-10-21 | 2018-05-01 | 鼎正动物药业（天津）有限公司 | A kind of Chinese medicine antiseptic for preventing aquaculture bacteriosis and preparation method thereof |
| CN115300426A (en) * | 2022-08-09 | 2022-11-08 | 深圳青春一九美业管理有限公司 | Lysozyme skin disinfectant with skin protection function and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN102697943B (en) | 2013-11-13 |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: REN BAOLIN Free format text: FORMER OWNER: YUAN JING Effective date: 20141124 |
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| C41 | Transfer of patent application or patent right or utility model | ||
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 250000 JINAN, SHANDONG PROVINCE TO: 226400 NANTONG, JIANGSU PROVINCE |
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| TR01 | Transfer of patent right |
Effective date of registration: 20141124 Address after: 226400 No. twelve, group 12, Zhang He Cun, Changsha Town, Rudong County, Jiangsu Patentee after: Ren Baolin Address before: 250000 General Hospital of Jinan Military Area, Tianqiao Road, Tianqiao District, Shandong, Ji'nan 25, China Patentee before: Yuan Jing |
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| TR01 | Transfer of patent right |
Effective date of registration: 20220408 Address after: 226400 Yangkou Port Economic Development Zone, Rudong County, Nantong City, Jiangsu Province Patentee after: Nantong Yangkou Port Labor Service Co.,Ltd. Address before: 226400 No.12, group 12, Zhanghe village, Changsha Town, Rudong County, Jiangsu Province Patentee before: Ren Baolin |
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| TR01 | Transfer of patent right |