CN101496784B - Chinese medicine shower lotion - Google Patents
Chinese medicine shower lotion Download PDFInfo
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- CN101496784B CN101496784B CN2009100942026A CN200910094202A CN101496784B CN 101496784 B CN101496784 B CN 101496784B CN 2009100942026 A CN2009100942026 A CN 2009100942026A CN 200910094202 A CN200910094202 A CN 200910094202A CN 101496784 B CN101496784 B CN 101496784B
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Abstract
The invention provides a bath liquid of traditional Chinese medicine. According to weight portion, 0.25 to 8 portions of hyacinth bletilla, 0.25 to 8 portions of root of omei mountain kudzuvine, 0.25 to 8 portions of flavescent sophora root and 0.25 to 8 portions of cnidium fruit are extracted to obtain a traditional Chinese medicine extract, and the traditional Chinese medicine extract is added with 68 to 99 portions of a substrate of a conventional bath liquid to prepare the bath liquid of the traditional Chinese medicine. The bath liquid has the efficacies of relieving itching and moisturizing the skin.
Description
Technical field
The present invention derives from the medicinal preparation of plant, specifically is a kind of Chinese medicine bath foam antipruritic, the skin moistening effect that has.
Background technology
Present commercially available bath foam is main component mostly with the soap lye, embodiment mainly be clean result, belong to the chemosynthesis articles for washing mostly, to a certain extent, mostly be chemical substance with toxic and side effects; The bath foam that has is added with a small amount of medicinal herb components, and its health-care effect is not ideal, and some health-cares are in the domestic existing exploitation of bath foam, application now, and its effect focuses mostly on and transferring muscles and bones, the meridian dredging; Improve looks; Aspects such as activating blood circulation to dissipate blood stasis and anti-skin, rheumatism.
The custom that health, health care and disease cure are cleaned with regard to natural plants such as the grass roots of useful aromatic odor, trees, floral leaves during time immemorial by China.Dipping is beneficial to outside muscle and the skin metabolism except having the circulation of the systemic blood of promotion, also has the effect of significant prevention and treatment disease, and " head has skin ulcer then to wash one's hair, and body has skin ulcer then to bathe." utilize the water temperature effect when taking a shower, add some Chinese herbal medicine again, can make the property of medicine act on skin hair key, play blood circulation promoting and blood stasis dispelling, profit flesh pool face effect after the absorption; Or effectively dispel the antibacterial and the acarid of skin, and antipruritic, increase effects such as skin resistance.Along with the quickening of people's rhythm of life, the raising day by day of living standard has Chinese medicine bath foam simple and practical, that have certain disease-treatment and health-care to be worth and more and more is subjected to broad masses' welcome.
Chinese patent 1259900 " a kind of preventing diseases and keeping fit bath foam " discloses a kind of putrefaction-removing granulation-promoting agent, the emollient of invigorating blood circulation, anti-inflammatory anti-itch agent, the agent of anti-dandruff black hair hair care, heat-clearing and toxic substances removing that is combined by 58 flavor Chinese herbal medicine and has pressed down the Chinese herbal medicine concentrated solution that the cancer agent is formed.
Chinese patent 1074114 discloses a kind of " medical bathing powder for relieving fatigue and preparation technology thereof ", it is to select Chinese medicine Ramulus Cinnamomi, Radix Angelicae Sinensis, Flos Carthami, Spina Gleditsiae, Radix Polygoni Multiflori, Pericarpium Zanthoxyli, Fructus Psoraleae, Radix Sophorae Flavescentis, Herba Schizonepetae, Fructus Cnidii, RADIX ACONITI LATERALIS PREPARATA, the Radix Angelicae Dahuricae and the dry and soft raw material of doing for use, and pulverizing, mixing, packing form.Many diseases such as psoriasis, dermatitis, eczema, beriberi are produced positive therapeutic.
Chinese patent 1131035 discloses " a kind of herbal composite ", it is to be the dip that raw material is made with Herba Ephedrae, Ramulus Cinnamomi, Fructus Forsythiae, Rhizoma Et Radix Notopterygii, Rhizoma Chuanxiong, Radix Bupleuri, the Radix Angelicae Dahuricae, Herba Schizonepetae, Radix Saposhnikoviae, Cortex Phellodendri, Radix Scutellariae, Radix Et Rhizoma Rhei, Cortex Fraxini, Rhizoma Curcumae, Rhizoma Osmundae, Radix Isatidis, Radix Sophorae Tonkinensis, Fructus Gardeniae, Fructus Toosendan, Galla Chinensis, the Fructus Kochiae, Fructus Cnidii, Herba Andrographis, Flos Lonicerae, Radix Sophorae Flavescentis, Herba Hyperici Japonici, Caulis Spatholobi, Cortex Dictamni, Cortex Pseudolaricis, has the effect of anti-mattress health care.
Chinese patent 1176099 discloses " a kind of bath foam ", is mixed by the leachate of the concentrated back of the water distillations such as fragrant flower bud, Flos Chrysanthemi Indici, Herba Pogostemonis, Herba Artemisiae Annuae and Herba Menthae of A group with Radix Isatidis.
It is too much that above patent relates to flavour of a drug, and processing technique is also comparatively complicated, has some medicinal raw materials to be subjected to the restriction of resource, should not supply with for a long time, influences the making of product.Therefore, the prescription that exploitation is good reduces and selects the medical material kind that is subjected to resource limit for use, improves the new trend that commercial production and coml adaptability are the exploitation health-care bathing liquids.
Summary of the invention
Purpose of the present invention is to provide a kind of prescription Chinese medicine bath foam simple and that prepare easily, effect antipruritic, skin moistening that this bath foam has.
The present invention is a kind of Chinese medicine bath foam antipruritic, the skin moistening effect that has, and it is characterized in that being made the conventional bath foam substrate that adds the 68-99 weight portion behind the Chinese medicine extract again and making through extracting by the Fructus Cnidii of the Radix Sophorae Flavescentis of the bitter Pueraria lobota of the Pseudobulbus Bletillae (Rhizoma Bletillae) of 0.25-8 weight portion, 0.25-8 weight portion, 0.25-8 weight portion, 0.25-8 weight portion.
Chinese medicine extract in the bath foam of the present invention can be made by following two kinds of methods:
Method one takes by weighing Pseudobulbus Bletillae (Rhizoma Bletillae), bitter Pueraria lobota, Radix Sophorae Flavescentis, Fructus Cnidii 4 flavor medical materials by weight, adds 5-10 water doubly, decocts two to three mixing, filter, filtrate is concentrated into 1/20 of original volume, adds ethanol to containing alcohol amount 60-80%, place, filter, vacuum drying gets Chinese medicine extract;
Method two extracts 4 flavor medical materials respectively earlier by purgation:
Pseudobulbus Bletillae (Rhizoma Bletillae): take by weighing Bletilla striata medicinal materials by weight, decocting boils twice, filters, and filtrate is concentrated into 1/20 of original volume, adds ethanol to containing alcohol amount 70%, places, and filters, and vacuum drying gets Pseudobulbus Bletillae (Rhizoma Bletillae) extract;
Bitter Pueraria lobota: take by weighing bitter Pueraria lobota medical material by weight, add 65% alcohol reflux twice, filter, decompression recycling ethanol, concentrated solution is put cold, filter, filtrate is directly gone up the D-101 macroporous adsorptive resins, waits to adsorb the back water flushing that finishes, the ethanol elution of reuse 80%, collect eluent, decompression recycling ethanol concentrates, vacuum drying gets bitter pueraria root extract;
Radix Sophorae Flavescentis: take by weighing Radix Sophorae Flavescentis medical material 1 weight portion, decocting boils 2 times, filters, and filtrate by macroporous adsorptive resins, after the washing, with volume fraction 80% ethanol elution, is collected eluent, concentrate, and water bath method, vacuum drying gets Radix Sophorae Flavescentis extract;
Fructus Cnidii: take by weighing the Fructus Cnidii medical material by weight, steam distillation extracts and got Fructus cnidii extract in 3 hours;
After obtaining each medicinal substances extract respectively, mix promptly getting Chinese medicine extract.
Method for making: get bath foam substrate aliphatic acid polyethenoxy ether ammonium sulfate or aliphatic acid polyethenoxy ether sulfosuccinic acid monoesters disodium salt, aliphatic acid polyethenoxy ether sodium sulfate, cocamido propyl betaine is heated to 60-80 ℃, stirs, and makes A liquid; Get glycerol, disodiumedetate, water solublity lanoline, water and be heated to 60-80 ℃, stir, make B liquid; Behind A liquid and B liquid mixing, add citric acid, coconut oil diethanol amide, Pearl Concentrate, mix homogeneously adds above-mentioned two kinds of Chinese medicine extract that any one method of method makes again, mix homogeneously, promptly.
Pseudobulbus Bletillae (Rhizoma Bletillae) in the Chinese medicine bath foam of the present invention is the dry tuber of orchid Pseudobulbus Bletillae (Rhizoma Bletillae) Bletillastriata (Thunb.) Reichb.f., has the effect of hemostasis convergence, detumescence and promoting granulation; Bitter Pueraria lobota is root Pueraria Peduncularis (Grah.ex Benth.) Benth of the bitter kudzu of leguminous plant, its clearing heat for promoting eruption, promoting the production of body fluid to quench thirst.Main cold, fever, measles without adequate eruption, quench one's thirst, haematemesis, aphtha; Radix Sophorae Flavescentis is the dry root of cassia leguminous plant Radix Sophorae Flavescentis (Sophora flavescens Ait.), has heat clearing and damp drying, parasite killing, diuresis effect; Fructus Cnidii is the dry mature fruit of umbrella shape annual herb plant cnidium monnieri (Cnidium monnieri (L.) Cuss.), is used for the treatment of surgery, gynecological, all diseases of skin more.
Prescription is a monarch drug with the Fructus Cnidii, and the effect of stronger sterilizing and itch-relieving is arranged; Bitter Pueraria lobota, Radix Sophorae Flavescentis are ministerial drug, strengthen the effect of its itch-stopping bactericidal; Pseudobulbus Bletillae (Rhizoma Bletillae) is an adjuvant drug, the energy skin care, thus play effect antipruritic, skin moistening jointly.
Carried out " antipruritic test ", " bacteriostatic test " experiment after making the Chinese medicine bath foam, the result shows:
1. the antipruritic test of bath foam extract
(1) 4-aminopyridine causes the experiment of itching
Experiment reference literature method is carried out, and mice is divided into blank group, model control group, positive drug group (three nine-day periods after the winter solstice PIYANPING group) and the basic, normal, high dosage group of test sample at random; 2d before the experiment, mouse back is shaved hair, and experiment same day, each administration group evenly is applied to relative medicine and shaves on the skin of hair-fields, and blank group and model control group are coated with the equivalent excipient, every group of administration 1 time.30min is in shaving the subcutaneous injection 4-aminopyridine 1mg/kg of hair place, blank group injection isometric(al) normal saline after the administration.Write down each treated animal and behind the injection 4-aminopyridine, lick the number of times of precursor reactant in the 10min.The result is as follows:
Test sample is licked the influence of precursor reactant number of times to the 4-aminopyridine induced mice
Annotate: compare with model control group: * p<0.05, * * p<0.01, * * * p<0.001
Experimental result shows, the basic, normal, high dosage group of test sample can suppress to lick the precursor reactant number of times due to the 4-aminopyridine in various degree, and suppression ratio is respectively 34.3%, 38.3%, 51.2%, after high dose group is given test sample, compare with the blank group, have significant difference (P<0.05).
(2) histamine phosphate causes the experiment of itching
The Cavia porcellus random packet, 1d before the experiment shaves hair, coating 1 time with each the right back instep of group Cavia porcellus portion.50min after the experiment administration on the same day, shave the hair place with No. 0 right back instep of sand paper scratch Cavia porcellus portion, and drip 0.01% 0.05mL/ of histamine phosphate in the wound surface place only, after this comply with 0.01%, 0.02%, 0.03%, 0.04% every 3min ... concentration increases progressively, only be 0.05mL/, till Cavia porcellus occurs later licking right back foot at every turn.The right back histamine phosphate's total amount that is given when sufficient occurring later licking with Cavia porcellus is itch-threshold, record and itch-threshold of each group relatively.The result is as follows:
Test sample is to the influence of Cavia porcellus itch-threshold due to the histamine phosphate
Annotate: compare with the blank group: * p<0.05, * * p<0.01, * * * p<0.001
Experimental result shows, the basic, normal, high dosage group of test sample can improve the itch-threshold due to the histamine phosphate in various degree, and the raising rate is respectively 31.3%, 53.9%, 59.6%, after high dose group is given test sample, compare with the blank group, have significant difference (P<0.05).
2. bath foam extract bacteriostatic test
Agar burrows diffusion method with streptococcus pneumoniae (10
10Individual/ml), escherichia coli (10
5Individual/ml), Shigella flexneri (10
5Individual/ml), Pseudomonas aeruginosa (10
5Individual/ml) and staphylococcus aureus (10
5Individual/ml), separate application is on the medicine ware flat board of thick about 6mm, and the hole that breaks into the about 6mm of diameter then therein is some, fills it up with test sample, cultivates 24h for 37 ℃, observes the inhibition zone size.
Test sample is to the influence of In vitro culture bacterial strain
Annotate: data are antibacterial circle diameter (mm) in the table; The growth of "+" expression indicator bacteria, no bacteriostasis.
Test sample has in various degree inhibitory action to bacillus pyocyaneus, shigella flexneri, bacillus coli, staphylococcus aureus, and its minimal inhibitory concentration is respectively 200mg/ml, 50mg/ml, 100mg/ml, 200mg/ml.
3. bath foam extract fungus inhibition test
3.1 strain: get common dermatomycosis pathomycete clinical separation strain, totally three kinds: trichophyton, trichophyton gypseum, Candida albicans.
3.2 bacterium liquid preparation: putting into physiological saline solution in right amount with inoculation hook picking, gently grind to form suspension, is 5 * 105CFU/ml at blood cell counting plate adjusted bacterial concentration.
3.3 other reagent instrument: distilled water, peptone, glucose, agar, the mould test tube of chlorine, sample injector, autoclave sterilizer, calorstat, microscope, microbalance, 20m syringe, 5ml syringe etc. is provided by department of dermatologry fungus laboratory.
3.4 experimental technique: prepare conventional sabouraud's agar, add series in vitro, every pipe 4ml.Get 140, be the 1-140 pipe.Extract 100% medicinal liquid 2ml with the 5ml syringe and add test tube 1ml, promptly make 20% medicinal liquid culture medium mixture; In the 5ml syringe of residue 1ml medicinal liquid, extract distilled water 1ml mixing and add next test tube 1ml, promptly make 10% medicinal liquid culture medium mixture so repeatedly, promptly make 20%, 10%, 5%, 2.5%, 1.25%, 0.625%, 0.3125% medicine series concentration culture medium mixture, carry out labelling simultaneously and get 2 in addition, promptly 141,142 manage, add distilled water 1ml, carry out labelling simultaneously, amount to 142.Behind 1.5 pounds of pressure high-temperature sterilizations of autoclave sterilizer 15min, put the inclined-plane, to be cooled, promptly prepare medicine series concentration culture medium and control medium 1-140 pipe, 141 pipes (growth control) are inoculated strain to be tested, put 25 ℃ of 2 weeks of calorstat together with 142 pipes (blank), observe the conk situation.Bacterium do not have fully growth ", the bacterium hypoevolutism, the bacterium colony of formation less " 1+ ", bacterium grows not vigorous " 2+ ", bacterium grows more vigorous, but bacterium colony more less than normally " 3+ ", bacterium blastoprolepsis vigorous " 4+ ".Minimum fungus does not have growth concentration fully and is the least concentration (MIC) that suppresses conk.Observe the colony growth situation.
Test sample is to the influence of In vitro culture bacterial strain
Test sample has in various degree inhibitory action to trichophyton, trichophyton gypseum, Candida albicans, and its minimal inhibitory concentration is respectively 100mg/ml, 200mg/ml, 200mg/ml.
In addition, also observed 100 routine people's result of use, 100 examples are the adult, age 25-65 year, and wherein male 60 examples, women 40 examples, equal free from infection histories, concrete result of use is shown in table 1-2.
Table 1100 example is used the satisfaction of this product
Number | Sex | Average access times | Very satisfied | Satisfied | Dissatisfied |
60 | The man | 6 | 45 | 15 | / |
40 | The woman | 5 | 30 | 10 | / |
The routine user applicable cases of table 2100
The example number | Skin pruritus is eliminated | The human body smoothness | The tired releasing |
Significant figure | 90 | 85 | 80 |
Invalid number | 10 | 15 | 20 |
Effective percentage (%) | 90% | 85% | 80% |
The specific embodiment
Implementation column 1:
Get Pseudobulbus Bletillae (Rhizoma Bletillae), bitter Pueraria lobota, Radix Sophorae Flavescentis, each 1 weight portions adding 5-10 of Fructus Cnidii 4 flavor medical materials water doubly, decoct two to three mixing, filter, filtrate is concentrated into 1/20 of original volume, adds ethanol to containing alcohol amount 60-80%, places, filter, vacuum drying gets Chinese medicine extract, and is standby;
Get bath foam substrate 96 weight portions commonly used, comprising: aliphatic acid polyethenoxy ether ammonium sulfate 5 weight portions, aliphatic acid polyethenoxy ether sodium sulfate 10 weight portions, cocamido propyl betaine 10 weight portions, glycerol 4 weight portions, citric acid 0.2 weight portion, disodiumedetate 0.1 weight portion, coconut oil diethanol amide 5 weight portions, Pearl Concentrate 3.5 weight portions, water 58.2 weight portions;
Method for making is: get aliphatic acid polyethenoxy ether ammonium sulfate 5 weight portions, aliphatic acid polyethenoxy ether sodium sulfate 10 weight portions, cocamido propyl betaine 10 weight portions and be heated to 60-80 ℃, stir, make A liquid; Get glycerol 4 weight portions, disodiumedetate 0.1 weight portion, water 57.2 weight portions and be heated to 60-80 ℃, stir, make B liquid; Behind A liquid and B liquid mixing, add citric acid 0.2 weight portion, coconut oil diethanol amide 5 weight portions, Pearl Concentrate 3.5 weight portions, mix homogeneously adds the above-mentioned Chinese medicine extract that makes again, mix homogeneously, promptly.
Implementation column 2:
Pseudobulbus Bletillae (Rhizoma Bletillae), bitter Pueraria lobota, Radix Sophorae Flavescentis, Fructus Cnidii 4 each 2.5 weight portion of flavor medical material, extract by purgation respectively:
Pseudobulbus Bletillae (Rhizoma Bletillae): take by weighing Bletilla striata medicinal materials 2.5 weight portions, decocting boils twice, filters, and filtrate is concentrated into 1/20 of original volume, adds ethanol to containing alcohol amount 70%, places, and filters, and vacuum drying gets Pseudobulbus Bletillae (Rhizoma Bletillae) extract;
Bitter Pueraria lobota: take by weighing bitter Pueraria lobota medical material 2.5 weight portions, add 65% alcohol reflux twice, filter, decompression recycling ethanol, concentrated solution is put cold, filter, filtrate is directly gone up the D-101 macroporous adsorptive resins, waits to adsorb the back water flushing that finishes, the ethanol elution of reuse 80%, collect eluent, decompression recycling ethanol concentrates, vacuum drying gets bitter pueraria root extract;
Radix Sophorae Flavescentis: take by weighing Radix Sophorae Flavescentis medical material 2.5 weight portions, decocting boils 2 times, filters, and filtrate by macroporous adsorptive resins, after the washing, with volume fraction 80% ethanol elution, is collected eluent, concentrate, and water bath method, vacuum drying gets Radix Sophorae Flavescentis extract;
Fructus Cnidii: take by weighing Fructus Cnidii medical material 2.5 weight portions, steam distillation extracts and got Fructus cnidii extract in 3 hours;
After obtaining each medicinal substances extract respectively, mix promptly getting Chinese medicine extract, standby;
Get bath foam substrate 90 weight portions commonly used, comprising: aliphatic acid polyethenoxy ether sodium sulfate 15 weight portions, aliphatic acid polyethenoxy ether sulfosuccinic acid monoesters disodium salt 10 weight portions, cocamido propyl betaine 10 weight portions, glycerol 3 weight portions, disodiumedetate 0.1 weight portion, water solublity lanoline 2 weight portions, citric acid 0.2 weight portion, coconut oil diethanol amide 5 weight portions, Pearl Concentrate 3.5 weight portions, water 41.2 weight portions
Method for making: get aliphatic acid polyethenoxy ether sodium sulfate 15 weight portions, aliphatic acid polyethenoxy ether sulfosuccinic acid monoesters disodium salt 10 weight portions, cocamido propyl betaine 10 weight portions and be heated to 60-80 ℃, stir, make A liquid; Get glycerol 3 weight portions, disodiumedetate 0.1 weight portion, water solublity lanoline 2 weight portions, water 41.2 weight portions and be heated to 60-80 ℃, stir, make B liquid; Behind A liquid and B liquid mixing, add citric acid 0.2 weight portion, coconut oil diethanol amide 5 weight portions, Pearl Concentrate 3.5 weight portions, mix homogeneously adds the above-mentioned Chinese medicine extract that makes again, mix homogeneously, promptly.
Claims (2)
1. one kind has Chinese medicine bath foam antipruritic, the skin moistening effect, it is characterized in that being made the conventional bath foam substrate that adds the 68-99 weight portion behind the Chinese medicine extract again and making through extracting by the Fructus Cnidii of the Radix Sophorae Flavescentis of the bitter Pueraria lobota of the Pseudobulbus Bletillae (Rhizoma Bletillae) of 0.25-8 weight portion, 0.25-8 weight portion, 0.25-8 weight portion, 0.25-8 weight portion, described Chinese medicine extract is made by following method:
Take by weighing Pseudobulbus Bletillae (Rhizoma Bletillae), bitter Pueraria lobota, Radix Sophorae Flavescentis, Fructus Cnidii 4 flavor medical materials by weight, add 5-10 water doubly, decoct two to three times, mix, filter, filtrate is concentrated into 1/20 of original volume, adds ethanol to containing alcohol amount 60-80%, place, filter, vacuum drying gets Chinese medicine extract.
2. one kind has Chinese medicine bath foam antipruritic, the skin moistening effect, it is characterized in that being made the conventional bath foam substrate that adds the 68-99 weight portion behind the Chinese medicine extract again and making through extracting by the Fructus Cnidii of the Radix Sophorae Flavescentis of the bitter Pueraria lobota of the Pseudobulbus Bletillae (Rhizoma Bletillae) of 0.25-8 weight portion, 0.25-8 weight portion, 0.25-8 weight portion, 0.25-8 weight portion, described Chinese medicine extract is made by following method:
Pseudobulbus Bletillae (Rhizoma Bletillae): take by weighing Bletilla striata medicinal materials by weight, decocting boils twice, filters, and filtrate is concentrated into 1/20 of original volume, adds ethanol to containing alcohol amount 70%, places, and filters, and vacuum drying gets Pseudobulbus Bletillae (Rhizoma Bletillae) extract;
Bitter Pueraria lobota: take by weighing bitter Pueraria lobota medical material by weight, add 65% alcohol reflux twice, filter, decompression recycling ethanol, concentrated solution is put cold, filter, filtrate is directly gone up the D-101 macroporous adsorptive resins, waits to adsorb the back water flushing that finishes, the ethanol elution of reuse 80%, collect eluent, decompression recycling ethanol concentrates, vacuum drying gets bitter pueraria root extract;
Radix Sophorae Flavescentis: take by weighing Radix Sophorae Flavescentis medical material 1 weight portion, decocting boils 2 times, filters, and filtrate after the washing, with volume fraction 80% ethanol elution, is collected eluent by macroporous adsorptive resins, concentrate, and water bath method, vacuum drying gets Radix Sophorae Flavescentis extract;
Fructus Cnidii: take by weighing the Fructus Cnidii medical material by weight, steam distillation extracts and got Fructus cnidii extract in 3 hours;
After obtaining each medicinal substances extract respectively, mix promptly getting Chinese medicine extract.
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Families Citing this family (4)
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CN102885738A (en) * | 2012-09-26 | 2013-01-23 | 上海群乐船舶附件启东有限公司 | Skin-protecting body lotion |
CN103893069A (en) * | 2014-03-27 | 2014-07-02 | 广东幸美化妆品股份有限公司 | Preparation method and application of effective ingredients of bletilla formosana |
CN105748355A (en) * | 2016-03-10 | 2016-07-13 | 蚌埠团结日用化学有限公司 | Chinese herbal medicine shower gel and preparation method thereof |
CN106176352A (en) * | 2016-07-20 | 2016-12-07 | 韩光泉 | A kind of antipruritic Traditional Chinese medicine bath powder |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN1110595A (en) * | 1994-12-23 | 1995-10-25 | 黄祥钗 | Traditional Chinese medicine for skin disease and its preparation method |
CN1329831A (en) * | 2000-06-17 | 2002-01-09 | 内蒙古苦参生化集团有限责任公司 | Disinfectant and its preparing process |
CN1824171A (en) * | 2006-01-10 | 2006-08-30 | 张怀森 | External use Chinese medicinal preparation for killing fungus and its preparation method |
CN101249232A (en) * | 2008-03-16 | 2008-08-27 | 李爱英 | Externally used Chinese medicine for curing pruritus dermatopathy relieve itching |
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2009
- 2009-03-13 CN CN2009100942026A patent/CN101496784B/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1110595A (en) * | 1994-12-23 | 1995-10-25 | 黄祥钗 | Traditional Chinese medicine for skin disease and its preparation method |
CN1329831A (en) * | 2000-06-17 | 2002-01-09 | 内蒙古苦参生化集团有限责任公司 | Disinfectant and its preparing process |
CN1824171A (en) * | 2006-01-10 | 2006-08-30 | 张怀森 | External use Chinese medicinal preparation for killing fungus and its preparation method |
CN101249232A (en) * | 2008-03-16 | 2008-08-27 | 李爱英 | Externally used Chinese medicine for curing pruritus dermatopathy relieve itching |
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Application publication date: 20090805 Assignee: Yunnan Baiyao Group Co.,Ltd. Assignor: YUNNAN INSTITUTE OF MATERIA MEDICA Contract record no.: X2022530000005 Denomination of invention: A traditional Chinese medicine bath liquid Granted publication date: 20110112 License type: Common License Record date: 20220624 |