CN102674975A - Nutrition protective agent capable of promoting content of camptothecin in camptotheca acuminata to increase - Google Patents
Nutrition protective agent capable of promoting content of camptothecin in camptotheca acuminata to increase Download PDFInfo
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- CN102674975A CN102674975A CN2012101705759A CN201210170575A CN102674975A CN 102674975 A CN102674975 A CN 102674975A CN 2012101705759 A CN2012101705759 A CN 2012101705759A CN 201210170575 A CN201210170575 A CN 201210170575A CN 102674975 A CN102674975 A CN 102674975A
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Abstract
The invention discloses a nutrition protective agent capable of promoting content of camptothecin in camptotheca acuminata to increase, and belongs to the technical field of nutrition of trees. The nutrition protective agent is characterized by comprising the following substances in percentage by weight: 13 to 37 percent of nutritional ingredient, 4 to 13 percent of growth hormone, 2 to 9 percent of preservative, 1 to 7 percent of synergistic agent and 43 to 71 percent of water. The nutrition protective agent capable of promoting the content of the camptothecin in the camptotheca acuminata to increase has various effects of promoting the content of the camptothecin in camptotheca acuminata fruits, camptotheca acuminata leaves and camptotheca acuminata branches to increase, the camptotheca acuminata to grow new roots and branches, the nursery stock and the branches of the camptotheca acuminata to extend and thicken and the camptotheca acuminata fruits to increase, can effectively prevent various diseases and pests of the trees and has a special effect of promoting the content of the camptothecin in the camptotheca acuminata to increase. The nutrition protective agent is easy and convenient to process, low in equipment investment and low in production cost, can be safely stored, transported and used and cannot pollute the environment, sources of raw materials are ensured, and the energy consumption is reduced.
Description
Technical field
The invention belongs to the tree nutrition technical field, be specially a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata.
Background technology
Camplotheca acuminata is the living xylophyta of a kind of speed, and is China's endemic tree, Nyssaceae.NSC 94600 is the vegeto-alkali in the camplotheca acuminata, is the actives that from Chinese crude drug Cortex Camptothecae Acuminatae, fruit, is extracted by American National ICR Monroe E. Wall etc., is a kind of pyrroles's steroid alkaloid NSC 94600.Quite effective to the indefatigable tumour of multiple medicine especially to various animal tumors.In the test of early 1970s, NSC 94600 is used to treat malignant tumours such as bladder cancer, cancer of the stomach, white blood disease clinically, but toxicity is bigger.To so far, the development research of relevant NSC 94600 constantly breaks through in every field, has the wide development prospect.
NSC 94600 is the vegeto-alkali that the camplotheca acuminata secondary metabolism is produced, and content is lower in each organ of camplotheca acuminata, how between 0.01%～0.1%.NSC 94600 is unique: water insoluble and common organic solvents, be soluble in chloroform, methyl alcohol, ethanol, acetate and ETHYLE ACETATE, and the E ring is the Alpha-hydroxy lactone.The chemosynthesis of NSC 94600 starts to walk very early, and research is deeply, existing more than ten kind of compound method, but route is long, productive rate is low, no actual production is worth, so the plant extraction is still the main stream approach that NSC 94600 is produced.All contain NSC 94600 in each organ of camplotheca acuminata, and Different Organs and same organ be at different development stage, the content difference of NSC 94600 is remarkable, but different investigator result and inconsistent.Early stage research thinks that the content of NSC 94600 is high in the fruit, and research in recent years shows, young tender tissue such as spire, sprout, and camptothecine content is high more.The average content of existing report camplotheca acuminata NSC 94600 from the stem apex that 8 leaves of vegetative point to the are formed is 4 times of whole plants over-ground part material average content.Liu Wenzhe etc. show that to Position Research in NSC 94600 accumulation and the tissue thereof in the camplotheca acuminata sprout camplotheca acuminata sprout can be used as the raw material that NSC 94600 is produced because of advantages such as its camptothecine content are high, output is big and can repeat to gather.
Promote the nourishment protecting agent of camptothecine content in the camplotheca acuminata to grow and growth rhythm for many years to make, have the prescription of multiple function to the xylophyta camplotheca acuminata.It has a kind of novel nourishing protective material of slowly-releasing, environmental protection, many integration such as efficient, easy to use concurrently; Can promote the root original hase to form the growth and the renewal of sprout, root hair; Camptothecine content in surviving rate of increase camplotheca acuminata nursery stock and the fruit; Increase dietetic alimentation ability of trees and the resistance of trees, possess unique market development potentiality.
Summary of the invention
To the problems referred to above that exist in the prior art, the objective of the invention is to design provides a kind of technical scheme that can promote the nourishment protecting agent of camptothecine content in the camplotheca acuminata, and it is low to have a cost, and effect is remarkable, natural environmental-protective, advantage such as without any side effects.
Described a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata is characterized in that containing the following material of weight percentage: nutritive ingredient 13-37%, tethelin 4-13%, sanitas 2-9%, synergistic agent 1-7%, water 43-71%;
Described nutritive ingredient is one or more mixtures in urea, sal epsom, calglucon, potassium hydrogenphosphate, ferrous sulfate, boric acid, zinc sulfate, ammonium molybdate, manganous sulfate, copper sulfate, the Sodium orthomolybdate; Described tethelin is one or more mixtures in Plant hormones regulators,gibberellins, phytokinin, PP-333, indolylacetic acid, indolebutyric acid, naphthylacetic acid, ethrel, kinetin, maleic hydrazide, the whole property element; Described sanitas is one or more mixtures in card pine, Hydrocerol A, neprotin, palmitinic acid, the Berberine; Described synergistic agent is one or more mixtures in Morpan BB, Whitfield's ointment, Sodium glycocholate, the Frosst).
Described a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata is characterized in that the content of nutritive ingredient is 15-30%, is preferably 18-25%.
Described a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata is characterized in that the content of growth regulator is 5-11%, is preferably 7-10%.
Described a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata is characterized in that the content of sanitas is 4-8%, is preferably 5-7%.
Described a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata is characterized in that the content of synergistic agent is 2-6%, is preferably 3-5%.
Described a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata is characterized in that the content of water is 45-69%, is preferably 50-65%.
When described a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata uses, nourishment protecting agent is diluted to 0.375g/ml.
Above-mentioned a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata; With water is medium; With arboreal growth must nutritive ingredient for relying on, dissolve in a certain proportion of tethelin and process meticulously with anticorrosion, synergistic agent, have camptothecine content in promotion Fructus Camptothecae Acuminatae, leaf of Common Camptotheca, the camplotheca acuminata branch; Make camplotheca acuminata germinate the elongation and the overstriking of new root shoot, promotion camplotheca acuminata nursery stock branch; Multiple efficacies such as Fructus Camptothecae Acuminatae increases can effectively be resisted the generation of the various disease and pests of trees, to promoting the content that improves NSC 94600 in the camplotheca acuminata special efficacy are arranged.Its simple and convenient processing method, facility investment is few, and raw material sources are guaranteed, energy efficient, storing and safe in utilization, low production cost and environment do not had any pollution.
The percentage composition that relates in the present specification unless otherwise indicated, other the weight percentage that is pure substance.
Embodiment
Combine embodiments of the invention at present, further specify beneficial effect of the present invention.
Embodiment 1
In the 1000L reaction kettle, drop into 670kg water; Drop into 36kg urea, 36kg sal epsom, 36kg calglucon, 36kg potassium hydrogenphosphate and 36kg Sodium orthomolybdate again; It is plain slowly to drop into the whole property of 10kg indolylacetic acid, 10kg indolebutyric acid, 10kg naphthylacetic acid, 10kg ethrel, 10kg kinetin, 10kg maleic hydrazide and 10kg after the stirring and dissolving again; Stir half a hour, mix, add 20kg neprotin, 15kg palmitinic acid and 15kg Berberine then; Add 20kg Sodium glycocholate and 10kg Frosst) at last, mix the finished product.
Embodiment 2
In the 1000L reaction kettle, drop into 470kg water; Drop into 31kg urea, 31kg sal epsom, 31kg calglucon, 31kg potassium hydrogenphosphate, 31kg ferrous sulfate, 31kg boric acid, 31kg zinc sulfate, 31kg manganous sulfate, 31kg copper sulfate and 31kg Sodium orthomolybdate again; It is plain slowly to drop into the whole property of 10kg Plant hormones regulators,gibberellins, 10kg phytokinin, 10kg PP-333,10kg indolylacetic acid, 10kg indolebutyric acid, 10kg naphthylacetic acid, 10kg ethrel, 10kg kinetin, 10kg maleic hydrazide and 10kg after the stirring and dissolving again; Stir half a hour; Mix; Add 20kg card pine, 20kg Hydrocerol A and 30kg Berberine then, add 10kg Morpan BB, 10kg Whitfield's ointment, 10kg Sodium glycocholate and 20kg Frosst) at last, mix the finished product.
Embodiment 3
In the 1000L reaction kettle, drop into 620kg water; Drop into 20kg potassium hydrogenphosphate, 20kg ferrous sulfate, 20kg boric acid, 20kg zinc sulfate, 20kg ammonium molybdate, 50kg manganous sulfate, 25kg copper sulfate and 25kg Sodium orthomolybdate again; It is plain slowly to drop into the whole property of 20kg Plant hormones regulators,gibberellins, 10kg phytokinin, 10kg PP-333,10kg ethrel, 10kg kinetin, 10kg maleic hydrazide and 10kg after the stirring and dissolving again; Stir half a hour, mix, add 15kg card pine, 15kg Hydrocerol A, 15kg neprotin and 15kg palmitinic acid then; Add 20kg Morpan BB, 10kg Whitfield's ointment and 10kg Sodium glycocholate at last, mix the finished product.
Embodiment 4
In the 1000L reaction kettle, drop into 513kg water; Drop into 35kg calglucon, 35kg potassium hydrogenphosphate, 30kg ferrous sulfate, 50kg boric acid, 50kg zinc sulfate, 25kg ammonium molybdate, 25kg manganous sulfate, 25kg copper sulfate and 25kg Sodium orthomolybdate again; It is plain slowly to drop into the whole property of 15kg Plant hormones regulators,gibberellins, 15kg phytokinin, 10kg PP-333,10kg indolylacetic acid, 10kg indolebutyric acid, 10kg naphthylacetic acid and 20kg after the stirring and dissolving again; Stir half a hour, mix, add 12kg card pine, 10kg Hydrocerol A, 10kg neprotin, 15kg palmitinic acid and 15kg Berberine then; Add the 35kg Frosst) at last, mix the finished product.
Embodiment 5
In the 1000L reaction kettle, drop into 565kg water; Drop into 30kg urea, 30kg sal epsom, 30kg calglucon, 30kg zinc sulfate, 30kg ammonium molybdate, 30kg manganous sulfate, 30kg copper sulfate and 40kg Sodium orthomolybdate again; It is plain slowly to drop into the whole property of 10kg Plant hormones regulators,gibberellins, 10kg PP-333,10kg indolylacetic acid, 10kg naphthylacetic acid, 10kg ethrel, 10kg kinetin and 15kg after the stirring and dissolving again; Stir half a hour, mix, add 20kg Hydrocerol A, 20kg neprotin and 25kg Berberine then; Add 20kg Whitfield's ointment and 25kg Frosst) at last, mix the finished product.
Embodiment 6
In the 1000L reaction kettle, drop into 608kg water; Drop into 25kg urea, 25kg sal epsom, 25kg calglucon, 25kg potassium hydrogenphosphate, 25kg ferrous sulfate, 25kg boric acid, 25kg zinc sulfate and 45kg ammonium molybdate again; Slowly drop into 15kg Plant hormones regulators,gibberellins, 10kg phytokinin, 10kg PP-333,10kg indolylacetic acid, 10kg indolebutyric acid, 10kg naphthylacetic acid, 10kg ethrel and 10kg kinetin after the stirring and dissolving again; Stir half a hour, mix, add 30kg card pine and 25kg palmitinic acid then; Add the 32kg Whitfield's ointment at last, mix the finished product.
Below further specify beneficial effect of the present invention through test.
Table 1 shows that embodiment 1-6 all has promoter action preferably to plant height rate of increase, over-ground part fresh weight and the side shoot quantity of handling the back seedling, has improved its growth indexes, and wherein embodiment 2,4, and 5 is best, and embodiment 1,3, and 6 take second place.
Table 2 embodiment 1-6 is to the influence of camptothecine content in the camplotheca acuminata Different Organs
| Handle | Leaf of Common Camptotheca % | Fruit of camptotheca acuminata % | Camplotheca acuminata branch % |
| Embodiment 1 | 0.196 | 0.189 | 0.176 |
| Embodiment 2 | 0.203 | 0.197 | 0.185 |
| Embodiment 3 | 0.201 | 0.192 | 0.181 |
| Embodiment 4 | 0.199 | 0.191 | 0.179 |
| Embodiment 5 | 0.197 | 0.195 | 0.186 |
| Embodiment 6 | 0.213 | 0.198 | 0.187 |
| Ck (clear water) | 0.167 | 0.156 | 0.147 |
Table two shows that camptothecine content all has promoter action preferably to embodiment 1-6 in the camplotheca acuminata Different Organs of back to handling, and wherein embodiment 2 is superior to embodiment 1, and embodiment 3 is superior to embodiment 4, and embodiment 6 is superior to embodiment 5, all apparently higher than control group.
Claims (6)
1. nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata is characterized in that containing the following material of weight percentage: nutritive ingredient 13-37%, tethelin 4-13%, sanitas 2-9%, synergistic agent 1-7%, water 43-71%;
Described nutritive ingredient is one or more mixtures in urea, sal epsom, calglucon, potassium hydrogenphosphate, ferrous sulfate, boric acid, zinc sulfate, ammonium molybdate, manganous sulfate, copper sulfate, the Sodium orthomolybdate; Described tethelin is one or more mixtures in Plant hormones regulators,gibberellins, phytokinin, PP-333, indolylacetic acid, indolebutyric acid, naphthylacetic acid, ethrel, kinetin, maleic hydrazide, the whole property element; Described sanitas is one or more mixtures in card pine, Hydrocerol A, neprotin, palmitinic acid, the Berberine; Described synergistic agent is one or more mixtures in Morpan BB, Whitfield's ointment, Sodium glycocholate, the Frosst).
2. a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata as claimed in claim 1 is characterized in that the content of nutritive ingredient is 15-30%, is preferably 18-25%.
3. a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata as claimed in claim 1 is characterized in that the content of growth regulator is 5-11%, is preferably 7-10%.
4. a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata as claimed in claim 1 is characterized in that the content of sanitas is 4-8%, is preferably 5-7%.
5. a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata as claimed in claim 1 is characterized in that the content of synergistic agent is 2-6%, is preferably 3-5%.
6. a kind of nourishment protecting agent that can promote camptothecine content in the camplotheca acuminata as claimed in claim 1 is characterized in that the content of water is 45-69%, is preferably 50-65%.
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| Application Number | Priority Date | Filing Date | Title |
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| CN2012101705759A CN102674975A (en) | 2012-05-29 | 2012-05-29 | Nutrition protective agent capable of promoting content of camptothecin in camptotheca acuminata to increase |
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| CN2012101705759A CN102674975A (en) | 2012-05-29 | 2012-05-29 | Nutrition protective agent capable of promoting content of camptothecin in camptotheca acuminata to increase |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103232285A (en) * | 2013-04-23 | 2013-08-07 | 苏州谷力生物科技有限公司 | Liquid compound fertilizer |
| CN103828619A (en) * | 2014-03-31 | 2014-06-04 | 东北林业大学 | Method for promoting growth of camptotheca acuminate and increasing content of camptothecin |
| CN107535330A (en) * | 2016-06-24 | 2018-01-05 | 苏州梵时轮园艺科技有限公司 | A kind of water root abductive approach of fleshy root type flowers |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101519325A (en) * | 2009-04-10 | 2009-09-02 | 广东省中药研究所 | Foliage promoter for improving camptothecine content of camptotheca acuminata |
| CN101548618A (en) * | 2009-05-11 | 2009-10-07 | 广东省中药研究所 | Camptotheca acuminata decne cultivation method for improving camptothecine content |
| CN101805218A (en) * | 2010-03-31 | 2010-08-18 | 吴洪生 | Preparation method of multifunctional leaf-spraying growth prompter and application thereof |
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2012
- 2012-05-29 CN CN2012101705759A patent/CN102674975A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101519325A (en) * | 2009-04-10 | 2009-09-02 | 广东省中药研究所 | Foliage promoter for improving camptothecine content of camptotheca acuminata |
| CN101548618A (en) * | 2009-05-11 | 2009-10-07 | 广东省中药研究所 | Camptotheca acuminata decne cultivation method for improving camptothecine content |
| CN101805218A (en) * | 2010-03-31 | 2010-08-18 | 吴洪生 | Preparation method of multifunctional leaf-spraying growth prompter and application thereof |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103232285A (en) * | 2013-04-23 | 2013-08-07 | 苏州谷力生物科技有限公司 | Liquid compound fertilizer |
| CN103828619A (en) * | 2014-03-31 | 2014-06-04 | 东北林业大学 | Method for promoting growth of camptotheca acuminate and increasing content of camptothecin |
| CN103828619B (en) * | 2014-03-31 | 2015-05-13 | 东北林业大学 | Method for promoting growth of camptotheca acuminate and increasing content of camptothecin |
| CN107535330A (en) * | 2016-06-24 | 2018-01-05 | 苏州梵时轮园艺科技有限公司 | A kind of water root abductive approach of fleshy root type flowers |
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