CN102670881B - Chinese medicinal composition for treating fracture and preparation method - Google Patents
Chinese medicinal composition for treating fracture and preparation method Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal composition for treating fracture, which comprises 9% to 11% by mass of apsaras centipede seven, 9% to 11% by mass of big bone-joining elixir, 7% to 9% by mass of white panax notoginseng, 2% to 4% by mass of drynaria total flavonoids, 2% to 4% by mass of syneilesis aconitifolia, 2% to 4% by mass of inch gold rattans, 4% to 6% by mass of wall ferns, 6% to 8% by mass of rhus chinensis, 2% to 4% by mass of red panax notoginseng, 1% to 3% by mass of Physaliastrum kweichouense, 4% to 6% by mass of sargentodoxa cuneata, 2% to 4% by mass of entada phaseoloides, 2% to 4% by mass of savage blood grasses, 2% to 4% by mass of flos carthami, 6% to 8% by mass of cotoneaster, 4% to 6% by mass of schisandraceane, 4% to 6% by mass of polygonum cuspidatum, 4% to 6% by mass of orthosipon aristatus, 0.05% to 0.15% by mass of musk, 0.05% to 0.15% by mass of ornel and 9.0% to 10.6% by mass of sugar, and the total of mass percentage of the components is 100%. The invention further discloses a method for preparing the Chinese medicinal composition for treating fracture, and the Chinese medicinal composition for treating fracture is obtained by mixing, addition of water and heating, is easy to absorb, obvious in curative effect and long in efficacy time, and does not have side effect.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate to a kind of Chinese medicine composition for the treatment of fracture, the invention still further relates to the preparation method of this Chinese medicine composition.
Background technology
Fracture is a kind of common disease.Existing Chinese traditional treatment fracture adopts the Drug therapy of taking Cortex torricelliae tiliifoliae class, and it is long that this type of mode is treated the fracture time, and effective ingredient is difficult for fried being absorbed by the body, and curative effect is undesirable.The ointment of the employing external also having spreads on affected part and uses clamping plate fixing bone, adopts this kind of mode ratio to take mode effective.But the existing fracture of controlling adopts medical herbs to mix to grind altogether mud shape more, applies the injury after reset, and the effect of the promoting blood circulation to remove blood stasis of this type of medical herbs is still not good, is difficult for absorbing, and curative effect time is longer, what have also has a toxic and side effects.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine composition for the treatment of fracture, easily absorb, evident in efficacy, effective drug duration is long, has no side effect.
Another object of the present invention is to provide the preparation method of above-mentioned Chinese medicine composition.
The technical solution adopted in the present invention is, a kind of Chinese medicine composition for the treatment of fracture, formed by following raw material according to mass percent: Caulis et Folium Pothi Repentis 9%-11%, Radix seu folium Gaultheriae intermediae 9%-11%, Herba Rhodiolae Henryi 7%-9%, Rhizoma Drynariae 2%-4%, Herba Syneilesis Aconitifoliae 2%-4%, very little golden rattan 2%-4%, Rhizoma Polypodiodis Nipponicae 4%-6%, Fructus rhois chinensis 6%-8%, Red Hill seven 2%-4%, Radix Ardisiae Punctatae 1%-3%, Caulis Sargentodoxae 4%-6%, Caulis Entadae 2%-4%, Herba Stylophori Lasiocapi 2%-4%, Flos Carthami 2%-4%, Rhizoma et radix panici repentis 6%-8%, brave 4%-6% goes up a hill, Rhizoma Polygoni Cuspidati 4%-6%, Herba clerodendranthi spicati 4%-6%, Moschus 0.05%-0.15%, Borneolum Syntheticum 0.05%-0.15%, sugar 9.0%-10.6%, the mass percent summation of above component is 100%.
Another technical scheme of the present invention is, the preparation method of the Chinese medicine composition of above-mentioned treatment fracture is specifically carried out according to following steps:
Step 1
According to mass percent, take Caulis et Folium Pothi Repentis 9%-11%, Radix seu folium Gaultheriae intermediae 9%-11%, Herba Rhodiolae Henryi 7%-9%, Rhizoma Drynariae 2%-4%, Herba Syneilesis Aconitifoliae 2%-4%, very little golden rattan 2%-4%, Rhizoma Polypodiodis Nipponicae 4%-6%, Fructus rhois chinensis 6%-8%, Red Hill seven 2%-4%, Radix Ardisiae Punctatae 1%-3%, Caulis Sargentodoxae 4%-6%, Caulis Entadae 2%-4%, Herba Stylophori Lasiocapi 2%-4%, Flos Carthami 2%-4%, Rhizoma et radix panici repentis 6%-8%, brave 4%-6% goes up a hill, Rhizoma Polygoni Cuspidati 4%-6%, Herba clerodendranthi spicati 4%-6%, Moschus 0.05%-0.15%, Borneolum Syntheticum 0.05%-0.15%, sugar 9.0%-10.6%, the mass percent summation of above component is 100%,
Step 2
By claim Caulis et Folium Pothi Repentis, Radix seu folium Gaultheriae intermediae, Herba Rhodiolae Henryi enter the very hot oven that adds water in pot and decoct 1-2 hour, filter out medicinal residues with filter, then add Rhizoma Drynariae, Herba Syneilesis Aconitifoliae, very little golden rattan, Rhizoma Polypodiodis Nipponicae, Fructus rhois chinensis, then endure 2-3 hour with very hot oven, then filter out medicinal residues with filter; Add again Red Hill seven, Radix Ardisiae Punctatae, Caulis Sargentodoxae, Caulis Entadae, Flos Carthami, Rhizoma et radix panici repentis, the tiger that goes up a hill, Rhizoma Polygoni Cuspidati, endure slowly and filter out medicinal residues in 2-3 hour with fiery slow fire, obtain liquid medicine a;
By claim Herba clerodendranthi spicati water slow fire endure slowly 1-2 hour except medicinal residues, obtain liquid medicine b;
The liquid medicine a that so latter two is endured and liquid medicine b merge and temperature is controlled to 80 DEG C endures slowly below until add Herba Stylophori Lasiocapi, sugar except fire when thick, and finally the temperature of medicine juice adds Moschus in the time of 10 DEG C, Borneolum Syntheticum obtains.
The invention has the beneficial effects as follows, can improve osteoblastic osteogenic activity, promote the growth of spur of defective region and the ability of calcification, can promote the reparation of fracture site osseous tissue, for the significant effect of having of union of fracture, easily absorb, effective drug duration is long, has no side effect.
Detailed description of the invention
Below by detailed description of the invention, the present invention is described in detail.
The Chinese medicine composition for the treatment of fracture of the present invention, is made up of following raw material according to mass percent:
Caulis et Folium Pothi Repentis 9%-11%, Radix seu folium Gaultheriae intermediae 9%-11%, Herba Rhodiolae Henryi 7%-9%, Rhizoma Drynariae 2%-4%, Herba Syneilesis Aconitifoliae 2%-4%, very little golden rattan 2%-4%, Rhizoma Polypodiodis Nipponicae 4%-6%, Fructus rhois chinensis 6%-8%, Red Hill seven 2%-4%, Radix Ardisiae Punctatae 1%-3%, Caulis Sargentodoxae 4%-6%, Caulis Entadae 2%-4%, Herba Stylophori Lasiocapi 2%-4%, Flos Carthami 2%-4%, Rhizoma et radix panici repentis 6%-8%, brave 4%-6% goes up a hill, Rhizoma Polygoni Cuspidati 4%-6%, Herba clerodendranthi spicati 4%-6%, Moschus 0.05%-0.15%, Borneolum Syntheticum 0.05%-0.15%, sugar 9.0%-10.6%, the mass percent summation of above component is 100%.
In the middle of the present invention,
Caulis et Folium Pothi Repentis, nature and flavor: mildly bitter flavor, Xin Xingping.Function: diuretic dehumidifying, promoting blood circulation and stopping pain, dissipating blood stasis synthetism.
Radix seu folium Gaultheriae intermediae, nature and flavor: sweet in the mouth, micro-bitterness temperature.Function: dissipating blood stasis for subsidence of swelling, removing the necrotic tissue and promoting granulation, the synthetism of invigorating blood circulation.
Herba Rhodiolae Henryi, nature and flavor: lightly seasoned, micro-bitterness is flat.Function: blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, strong muscle symplectic bone, traumatic injury.
Rhizoma Drynariae, nature and flavor: warm in nature, bitter in the mouth.Function: invigorating the liver and kidney, reuniting the fractured tendons and bones, treatment bone injury.
Herba Syneilesis Aconitifoliae, nature and flavor; Taste is sweet arduous, warm in nature.Function: promoting blood circulation and detoxication, reducing swelling and alleviating pain, traumatic injury.
Very little golden rattan, nature and flavor; Slightly sweet flavor, property are put down.Function: bone and muscle strengthening, tune muscle are invigorated blood circulation, broken bone para-position.
Rhizoma Polypodiodis Nipponicae, nature and flavor; Bitter in the mouth, adstringency are put down.Function: promoting flow of QI and blood, detumescence dissipating blood stasis, dispelling wind and removing obstruction in the collateral.
Fructus rhois chinensis, nature and flavor; Salty in the mouth, bitterness are cool.Function: promoting blood circulation to remove blood stasis, heat-clearing and toxic substances removing, traumatic injury.
Red Hill seven, nature and flavor; Lightly seasoned, micro-puckery, micro-fiber crops are cool in nature.Function: expelling wind and activating blood circulation, reducing swelling and alleviating pain, relieving iching by astringing.
Radix Ardisiae Punctatae, nature and flavor; Bitter in the mouth, Gan Xingping.Function: blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, dredge the meridian passage, soft tissue injury.
Caulis Sargentodoxae, nature and flavor; Bitter in the mouth, micro-adstringency are put down.Function: vital energy regualting and blood circulation-promoting, dispersing swelling and dissipating binds, traumatic injury.
Caulis Entadae, nature and flavor; Sweet in the mouth, warm in nature.Function: relaxing muscles and tendons to promote blood circulation, reducing swelling and alleviating pain, removing toxic substances.
Herba Stylophori Lasiocapi, nature and flavor; Bitter in the mouth, adstringency are put down.Function: blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, hemostasis removing toxic substances.
Flos Carthami, nature and flavor; Acrid in the mouth, warm in nature.Function: removing blood stasis to promote tissue regeneration.
Rhizoma et radix panici repentis, nature and flavor; Bitter in the mouth, micro-pungent cool in nature.Function: blood circulation promoting and blood stasis dispelling, putrefaction-removing granulation-promoting, osteocarcinoma swell and ache, osteomyelitis.
Go up a hill tiger, nature and flavor; Acrid in the mouth, warm in nature.Function: eliminating stasis to stop pain, long bone.
Rhizoma Polygoni Cuspidati, nature and flavor; Bitter in the mouth, cold in nature.Function: blood circulation promoting competent silt, osteonecrosis, traumatic injury.
Herba clerodendranthi spicati, nature and flavor; Bitter in the mouth, pungent warm in nature.Function: bone and muscle strengthening, traumatic injury.
Moschus, nature and flavor; Acrid in the mouth, warm in nature.Function: dredge the meridian passage, pain relieving.
Borneolum Syntheticum, nature and flavor; Acrid in the mouth, bitterness are slightly cold.Function: pain relieving granulation promoting, anticorrosion.
Sugar, nature and flavor; Sweet in the mouth, warm in nature.Function: promoting flow of QI and blood, adhesive function.
Wherein, Caulis et Folium Pothi Repentis, Radix seu folium Gaultheriae intermediae, three step Cortex torricelliae tiliifoliaes are monarch drug, cure mainly traumatic injury.Rhizoma Drynariae, Herba Syneilesis Aconitifoliae, very little golden rattan, Rhizoma Polypodiodis Nipponicae, Fructus rhois chinensis are ministerial drug, reducing swelling and alleviating pain, blood circulation promoting and blood stasis dispelling, help monarch to control bone.Red Hill seven, Radix Ardisiae Punctatae, Caulis Sargentodoxae, Caulis Entadae, Herba Stylophori Lasiocapi, Flos Carthami are adjuvant drug, strong muscle symplectic bone, dispersing swelling and dissipating binds, removing blood stasis to promote tissue regeneration, urge the raw crust of bone.Rhizoma et radix panici repentis, the tiger that goes up a hill, Rhizoma Polygoni Cuspidati, Herba clerodendranthi spicati, Moschus, Borneolum Syntheticum be for making medicine, with muscle invigorate blood circulation, removing the necrotic tissue and promoting granulation, protection skin.
The preparation method of the Chinese medicine composition for the treatment of fracture of the present invention, specifically carry out according to following steps:
Step 1
According to mass percent, take Caulis et Folium Pothi Repentis 9%-11%, Radix seu folium Gaultheriae intermediae 9%-11%, Herba Rhodiolae Henryi 7%-9%, Rhizoma Drynariae 2%-4%, Herba Syneilesis Aconitifoliae 2%-4%, very little golden rattan 2%-4%, Rhizoma Polypodiodis Nipponicae 4%-6%, Fructus rhois chinensis 6%-8%, Red Hill seven 2%-4%, Radix Ardisiae Punctatae 1%-3%, Caulis Sargentodoxae 4%-6%, Caulis Entadae 2%-4%, Herba Stylophori Lasiocapi 2%-4%, Flos Carthami 2%-4%, Rhizoma et radix panici repentis 6%-8%, brave 4%-6% goes up a hill, Rhizoma Polygoni Cuspidati 4%-6%, Herba clerodendranthi spicati 4%-6%, Moschus 0.05%-0.15%, Borneolum Syntheticum 0.05%-0.15%, sugar 9.0%-10.6%, the mass percent summation of above component is 100%,
Step 2
By claim Caulis et Folium Pothi Repentis, Radix seu folium Gaultheriae intermediae, Herba Rhodiolae Henryi enter the very hot oven that adds water in pot and decoct 1-2 hour, filter out medicinal residues with filter, then add Rhizoma Drynariae, Herba Syneilesis Aconitifoliae, very little golden rattan, Rhizoma Polypodiodis Nipponicae, Fructus rhois chinensis, then endure 2-3 hour with very hot oven, then filter out medicinal residues with filter; Add again Red Hill seven, Radix Ardisiae Punctatae, Caulis Sargentodoxae, Caulis Entadae, Flos Carthami, Rhizoma et radix panici repentis, the tiger that goes up a hill, Rhizoma Polygoni Cuspidati, endure slowly and filter out medicinal residues in 2-3 hour with fiery slow fire, obtain liquid medicine a;
By claim Herba clerodendranthi spicati water slow fire endure slowly 1-2 hour except medicinal residues, obtain liquid medicine b;
The liquid medicine a that so latter two is endured and liquid medicine b merge and temperature is controlled to 80 DEG C endures slowly below until add Herba Stylophori Lasiocapi, sugar except fire when thick, and finally the temperature of medicine juice adds Moschus in the time of 10 DEG C, Borneolum Syntheticum obtains.
The using method of Chinese medicine of the present invention
After fracture reduction, depending on the large cabinet cream paper in sick position, coat ointment of the present invention, be attached to affected part, within three to five days, change dressings once, each consumption is five grams of little wounds, hinders greatly eight grams.
Pharmacodynamic experiment:
Animal and modeling
Select 32 of rabbit, body weight 1.4～2.3kg, male and female dual-purpose, is divided into blank group at random, and Chinese medicine composition that the present invention treats fracture is low, high dose group, bone setting tablet positive control, 8 every group.3% pentobarbital 1ml/kg intravenous anesthesia, aseptic condition menisectomy separates the two forelimb radius of rabbit, causes hypomere incomplete fracture in bilateral radius with double-deck hacksaw, the wide about 3mm of fracture, the degree of depth is 1/2 of radius diameter, sews up subcutaneous tissue and skin, intramuscular injection gentamycin 40,000 U infection.Started medication experiment in postoperative one week.Blank treated animal routine feeding, medication is low, high dose group is admixed feedstuff administration by 0.45g/kg and 0.90g/kg body weight by medicine respectively; Positive controls is admixed forage feed to bone setting tablet 0.42g/kg body weight by medicine.After fasting in morning 4h, be fed with medicine feedstuff, rabbit eats up pastille feedstuff conventionally in 2h, then gives normal diet.Postoperatively weigh once weekly, and adjust dosage according to body weight.
Assay method
Blood sample analysis: with etherization, get jugular vein blood 2ml, serum put-20 DEG C freezing, centralized and unified mensuration.The content of serum alkaline phosphatase adopts King's method to measure, and measures respectively at after modeling 10,20 and 30 days.
Callus is analyzed: within 30 days after modeling, put to death animal, from disconnected Wrist elbow joint, take whole left radius, the soft tissue that rejecting is adhered to, cold drying is to constant weight, and (every 10mg dry sample adds 3ml trichloroacetic acid to the trichloroacetic acid solution hydrolysis callus with 10%, cohydrolysis three times, merges hydrolyzed solution).With calcium content in EDTA complexometric titration callus, measure phosphorus content in callus with ferrous sulfate occluded corrosion cell, use collagen content in dimethylbenzaldehyde colorimetric method for determining callus.
X sheet: after two radius callus take with 70% ethanol (4 DEG C) all material,, by callus specimen X sheet, 15 days and 30 days shooting conditions are 50kv, 013s.
Fracture resistence force test: carrying out fracture resistence force test with right radius.
Instrument: 721-ultraviolet-uisible spectrophotometer.Agents useful for same is analytical pure.
Statistical procedures: with electrical form, the detection index of each treated animal is added up and drawn meansigma methods and standard deviation, evaluate the significance of indices with T inspection and X 2 test.
Measurement result:
Serum alkaline phosphatase: respectively at 10,20,30 days mensuration rabbit anteserum alkali phosphatases after modeling, medication low dose group and matched group comparing difference have significant (P < 0.05), especially after modeling, 20 days serum alkaline phosphatases increase than matched group, and difference has extremely significantly meaning (P < 0.01).Medication low dose group is compared difference nonsignificance (P > 0.05) with bone setting tablet group, illustrate that Chinese medicine composition of the present invention can improve osteoblastic osteogenic activity.
Calcium, phosphorus content and calcium/phosphorus ratio in callus: medication low dose group callus calcium, phosphorus and calcium phosphorus ratio are apparently higher than matched group (P < 01001, P < 0101, P < 0105), difference nonsignificance compared with bone setting tablet (P < 0.05), illustrates that medication low dose group has the growth of spur of defective region of promotion and the ability of calcification.
Collagen content in callus: medication low dose group collagen content difference compared with matched group has extremely significantly meaning (P < 0.01), but no significant difference compared with bone setting tablet (P > 0.05), illustrates that medication low dose group can promote the reparation of fracture site osseous tissue.
X-ray scoring is analyzed: by callus projection broken ends of fractured bone edge, and periosteal reaction, callus structure, callus density, 5, callus edge index evaluation healing.Between organizing relatively, the each administration group of result and matched group relatively have significant difference in employing X 2 test.Medication low dose group and bone setting tablet group healing are obviously better than matched group.
Radius fracture resistence force: medication low dose group and matched group difference have remarkable statistical significance.(P＜0.001)。Zero difference compared with bone setting tablet group (P > 0.05).Variant between medication high dose group and matched group have a statistical significance (P < 0.05).Illustrate that medication of the present invention is low, high dose group all has the effect that promotes union of fracture, especially more obvious with high dose group.
Toxicity test:
Give 40 fracture patient affected part spreadings by Chinese medicine composition of the present invention, do not find toxic reaction, observe 1-72 hour without toxic reaction, there is no anaphylaxis.
Embodiment 1
According to mass percent, take Caulis et Folium Pothi Repentis content 10%, Radix seu folium Gaultheriae intermediae 10%, Herba Rhodiolae Henryi 8%, Rhizoma Drynariae 3%, Herba Syneilesis Aconitifoliae 3%, very little golden rattan 3%, Rhizoma Polypodiodis Nipponicae 5%, Fructus rhois chinensis 7%, Red Hill 7 3%, Radix Ardisiae Punctatae 2%, Caulis Sargentodoxae 5%, Caulis Entadae 3%, Herba Stylophori Lasiocapi 3%, Flos Carthami 3%, Rhizoma et radix panici repentis 7%, go up a hill tiger 5%, Rhizoma Polygoni Cuspidati 5%, Herba clerodendranthi spicati 5%, Moschus 0.1%, Borneolum Syntheticum 0.1%, sugar 9.8%; By claim Caulis et Folium Pothi Repentis, Radix seu folium Gaultheriae intermediae, Herba Rhodiolae Henryi enter the very hot oven that adds water in pot and decoct 1 hour, filter out medicinal residues with filter, then add Rhizoma Drynariae, Herba Syneilesis Aconitifoliae, very little golden rattan, Rhizoma Polypodiodis Nipponicae, Fructus rhois chinensis, then endure 2 hours with very hot oven, then filter out medicinal residues with filter; Add again Red Hill seven, Radix Ardisiae Punctatae, Caulis Sargentodoxae, Caulis Entadae, Flos Carthami, Rhizoma et radix panici repentis, the tiger that goes up a hill, Rhizoma Polygoni Cuspidati, endure slowly and filter out medicinal residues in 2 hours with fiery slow fire, obtain liquid medicine a; By claim Herba clerodendranthi spicati water slow fire endure slowly 1 hour except medicinal residues, obtain liquid medicine b; The liquid medicine a that so latter two is endured and liquid medicine b merge and temperature is controlled to 75 DEG C endures slowly until add Herba Stylophori Lasiocapi, sugar except fire when thick, and finally the temperature of medicine juice adds Moschus in the time of 10 DEG C, Borneolum Syntheticum obtains.
Embodiment 2
According to mass percent, take Caulis et Folium Pothi Repentis content 9.8%, Radix seu folium Gaultheriae intermediae 9%, Herba Rhodiolae Henryi 7%, Rhizoma Drynariae 2%, Herba Syneilesis Aconitifoliae 2%, very little golden rattan 2%, Rhizoma Polypodiodis Nipponicae 4%, Fructus rhois chinensis 6%, Red Hill 7 2%, Radix Ardisiae Punctatae 3%, Caulis Sargentodoxae 6%, Caulis Entadae 4%, Herba Stylophori Lasiocapi 4%, Flos Carthami 4%, Rhizoma et radix panici repentis 8%, go up a hill tiger 6%, Rhizoma Polygoni Cuspidati 6%, Herba clerodendranthi spicati 6%, Moschus 0.05%, Borneolum Syntheticum 0.15%, sugar 9.0%; By claim Caulis et Folium Pothi Repentis, Radix seu folium Gaultheriae intermediae, Herba Rhodiolae Henryi enter the very hot oven that adds water in pot and decoct 2 hours, filter out medicinal residues with filter, then add Rhizoma Drynariae, Herba Syneilesis Aconitifoliae, very little golden rattan, Rhizoma Polypodiodis Nipponicae, Fructus rhois chinensis, then endure 3 hours with very hot oven, then filter out medicinal residues with filter; Add again Red Hill seven, Radix Ardisiae Punctatae, Caulis Sargentodoxae, Caulis Entadae, Flos Carthami, Rhizoma et radix panici repentis, the tiger that goes up a hill, Rhizoma Polygoni Cuspidati, endure slowly and filter out medicinal residues in 3 hours with fiery slow fire, obtain liquid medicine a; By claim Herba clerodendranthi spicati water slow fire endure slowly 2 hours except medicinal residues, obtain liquid medicine b; The liquid medicine a that so latter two is endured and liquid medicine b merge and temperature is controlled to 78 DEG C endures slowly until add Herba Stylophori Lasiocapi, sugar except fire when thick, and finally the temperature of medicine juice adds Moschus in the time of 10 DEG C, Borneolum Syntheticum obtains.
Embodiment 3
According to mass percent, take Caulis et Folium Pothi Repentis content 11%, Radix seu folium Gaultheriae intermediae 11%, Herba Rhodiolae Henryi 9%, Rhizoma Drynariae 4%, Herba Syneilesis Aconitifoliae 4%, very little golden rattan 4%, Rhizoma Polypodiodis Nipponicae 6%, Fructus rhois chinensis 8%, Red Hill 7 4%, Radix Ardisiae Punctatae 1%, Caulis Sargentodoxae 4%, Caulis Entadae 2%, Herba Stylophori Lasiocapi 2%, Flos Carthami 2%, Rhizoma et radix panici repentis 6%, go up a hill tiger 4%, Rhizoma Polygoni Cuspidati 4%, Herba clerodendranthi spicati 4%, Moschus 0.15%, Borneolum Syntheticum 0.05%, sugar 9.8%; By claim Caulis et Folium Pothi Repentis, Radix seu folium Gaultheriae intermediae, Herba Rhodiolae Henryi enter the very hot oven that adds water in pot and decoct 1.5 hours, filter out medicinal residues with filter, then add Rhizoma Drynariae, Herba Syneilesis Aconitifoliae, very little golden rattan, Rhizoma Polypodiodis Nipponicae, Fructus rhois chinensis, then endure 2.5 hours with very hot oven, then filter out medicinal residues with filter; Add again Red Hill seven, Radix Ardisiae Punctatae, Caulis Sargentodoxae, Caulis Entadae, Flos Carthami, Rhizoma et radix panici repentis, the tiger that goes up a hill, Rhizoma Polygoni Cuspidati, endure slowly and filter out medicinal residues in 2.5 hours with fiery slow fire, obtain liquid medicine a; By claim Herba clerodendranthi spicati water slow fire endure slowly 1.5 hours except medicinal residues, obtain liquid medicine b; The liquid medicine a that so latter two is endured and liquid medicine b merge and temperature is controlled to 80 DEG C endures slowly until add Herba Stylophori Lasiocapi, sugar except fire when thick, and finally the temperature of medicine juice adds Moschus in the time of 10 DEG C, Borneolum Syntheticum obtains.
Embodiment 4
According to mass percent, take Caulis et Folium Pothi Repentis content 9%, Radix seu folium Gaultheriae intermediae 10.2%, Herba Rhodiolae Henryi 8%, Rhizoma Drynariae 3%, Herba Syneilesis Aconitifoliae 3%, very little golden rattan 3%, Rhizoma Polypodiodis Nipponicae 5%, Fructus rhois chinensis 7%, Red Hill 7 3%, Radix Ardisiae Punctatae 2%, Caulis Sargentodoxae 5%, Caulis Entadae 3%, Herba Stylophori Lasiocapi 3%, Flos Carthami 3%, Rhizoma et radix panici repentis 7%, go up a hill tiger 5%, Rhizoma Polygoni Cuspidati 5%, Herba clerodendranthi spicati 5%, Moschus 0.1%, Borneolum Syntheticum 0.1%, sugar 10.6%; By claim Caulis et Folium Pothi Repentis, Radix seu folium Gaultheriae intermediae, Herba Rhodiolae Henryi enter the very hot oven that adds water in pot and decoct 1.5 hours, filter out medicinal residues with filter, then add Rhizoma Drynariae, Herba Syneilesis Aconitifoliae, very little golden rattan, Rhizoma Polypodiodis Nipponicae, Fructus rhois chinensis, then endure 2.5 hours with very hot oven, then filter out medicinal residues with filter; Add again Red Hill seven, Radix Ardisiae Punctatae, Caulis Sargentodoxae, Caulis Entadae, Flos Carthami, Rhizoma et radix panici repentis, the tiger that goes up a hill, Rhizoma Polygoni Cuspidati, endure slowly and filter out medicinal residues in 2.5 hours with fiery slow fire, obtain liquid medicine a; By claim Herba clerodendranthi spicati water slow fire endure slowly 1.5 hours except medicinal residues, obtain liquid medicine b; The liquid medicine a that so latter two is endured and liquid medicine b merge and temperature is controlled to 80 DEG C endures slowly until add Herba Stylophori Lasiocapi, sugar except fire when thick, and finally the temperature of medicine juice adds Moschus in the time of 10 DEG C, Borneolum Syntheticum obtains.
Claims (2)
1. a Chinese medicine composition for the treatment of fracture, is characterized in that, is made up of following raw material according to mass percent:
Caulis et Folium Pothi Repentis 9%-11%, Radix seu folium Gaultheriae intermediae 9%-11%, Herba Rhodiolae Henryi 7%-9%, Rhizoma Drynariae 2%-4%, Herba Syneilesis Aconitifoliae 2%-4%, very little golden rattan 2%-4%, Rhizoma Polypodiodis Nipponicae 4%-6%, Fructus rhois chinensis 6%-8%, Red Hill seven 2%-4%, Radix Ardisiae Punctatae 1%-3%, Caulis Sargentodoxae 4%-6%, Caulis Entadae 2%-4%, Herba Stylophori Lasiocapi 2%-4%, Flos Carthami 2%-4%, Rhizoma et radix panici repentis 6%-8%, brave 4%-6% goes up a hill, Rhizoma Polygoni Cuspidati 4%-6%, Herba clerodendranthi spicati 4%-6%, Moschus 0.05%-0.15%, Borneolum Syntheticum 0.05%-0.15%, sugar 9.0%-10.6%, the mass percent summation of above component is 100%.
2. a preparation method for the treatment of the Chinese medicine composition of fracture, is characterized in that, specifically carries out according to following steps:
Step 1
According to mass percent, take Caulis et Folium Pothi Repentis 9%-11%, Radix seu folium Gaultheriae intermediae 9%-11%, Herba Rhodiolae Henryi 7%-9%, Rhizoma Drynariae 2%-4%, Herba Syneilesis Aconitifoliae 2%-4%, very little golden rattan 2%-4%, Rhizoma Polypodiodis Nipponicae 4%-6%, Fructus rhois chinensis 6%-8%, Red Hill seven 2%-4%, Radix Ardisiae Punctatae 1%-3%, Caulis Sargentodoxae 4%-6%, Caulis Entadae 2%-4%, Herba Stylophori Lasiocapi 2%-4%, Flos Carthami 2%-4%, Rhizoma et radix panici repentis 6%-8%, brave 4%-6% goes up a hill, Rhizoma Polygoni Cuspidati 4%-6%, Herba clerodendranthi spicati 4%-6%, Moschus 0.05%-0.15%, Borneolum Syntheticum 0.05%-0.15%, sugar 9.0%-10.6%, the mass percent summation of above component is 100%,
Step 2
By claim Caulis et Folium Pothi Repentis, Radix seu folium Gaultheriae intermediae, Herba Rhodiolae Henryi enter the very hot oven that adds water in pot and decoct 1-2 hour, filter out medicinal residues with filter, then add Rhizoma Drynariae, Herba Syneilesis Aconitifoliae, very little golden rattan, Rhizoma Polypodiodis Nipponicae, Fructus rhois chinensis, then endure 2-3 hour with very hot oven, then filter out medicinal residues with filter; Add again Red Hill seven, Radix Ardisiae Punctatae, Caulis Sargentodoxae, Caulis Entadae, Flos Carthami, Rhizoma et radix panici repentis, the tiger that goes up a hill, Rhizoma Polygoni Cuspidati, endure slowly and filter out medicinal residues in 2-3 hour with fiery slow fire, obtain liquid medicine a;
By claim Herba clerodendranthi spicati water slow fire endure slowly 1-2 hour except medicinal residues, obtain liquid medicine b;
The liquid medicine a that so latter two is endured and liquid medicine b merge and temperature is controlled to 80 DEG C endures slowly below until add Herba Stylophori Lasiocapi, sugar except fire when thick, and finally the temperature of medicine juice adds Moschus in the time of 10 DEG C, Borneolum Syntheticum obtains.
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| CN1293057A (en) * | 2000-10-24 | 2001-05-02 | 黄学祥 | Medicine for treating bone fracture and injury |
| CN1362256A (en) * | 2001-12-26 | 2002-08-07 | 邹明义 | Osteological Chinese medicine prepn. |
| CN102091202A (en) * | 2011-01-17 | 2011-06-15 | 赵献民 | Traditional Chinese medicinal composition for treating fracture and preparation method thereof |
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| CN1362256A (en) * | 2001-12-26 | 2002-08-07 | 邹明义 | Osteological Chinese medicine prepn. |
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