CN102670715A - Cordyceps sinensis mycelium oral liquid - Google Patents
Cordyceps sinensis mycelium oral liquid Download PDFInfo
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- CN102670715A CN102670715A CN2012101387296A CN201210138729A CN102670715A CN 102670715 A CN102670715 A CN 102670715A CN 2012101387296 A CN2012101387296 A CN 2012101387296A CN 201210138729 A CN201210138729 A CN 201210138729A CN 102670715 A CN102670715 A CN 102670715A
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- cordyceps mycelium
- oral liquid
- extracting solution
- cordyceps
- arillus longan
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- 239000007788 liquid Substances 0.000 title claims abstract description 32
- 241001248610 Ophiocordyceps sinensis Species 0.000 title abstract 6
- 239000000843 powder Substances 0.000 claims abstract description 24
- 235000000235 Euphoria longan Nutrition 0.000 claims abstract description 22
- 238000004519 manufacturing process Methods 0.000 claims abstract description 10
- 239000000284 extract Substances 0.000 claims abstract description 7
- 238000002360 preparation method Methods 0.000 claims abstract description 7
- 241000190633 Cordyceps Species 0.000 claims description 57
- 240000001008 Dimocarpus longan Species 0.000 claims description 21
- 238000000605 extraction Methods 0.000 claims description 15
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 235000010355 mannitol Nutrition 0.000 claims description 6
- 238000010792 warming Methods 0.000 claims description 6
- 239000012141 concentrate Substances 0.000 claims description 5
- 239000005909 Kieselgur Substances 0.000 claims description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 4
- 238000001914 filtration Methods 0.000 claims description 4
- 230000001954 sterilising effect Effects 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 239000002075 main ingredient Substances 0.000 claims description 3
- 230000008569 process Effects 0.000 claims description 3
- 238000003556 assay Methods 0.000 claims description 2
- 238000013329 compounding Methods 0.000 claims description 2
- 238000003809 water extraction Methods 0.000 claims description 2
- 238000005457 optimization Methods 0.000 claims 1
- 230000036541 health Effects 0.000 abstract description 4
- 239000003086 colorant Substances 0.000 abstract description 2
- 235000012907 honey Nutrition 0.000 abstract description 2
- 244000139609 Euphoria longan Species 0.000 abstract 1
- 239000003755 preservative agent Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 239000000047 product Substances 0.000 description 7
- 241000233866 Fungi Species 0.000 description 5
- -1 al Species 0.000 description 5
- 240000001307 Myosotis scorpioides Species 0.000 description 4
- 238000005516 engineering process Methods 0.000 description 4
- 206010062717 Increased upper airway secretion Diseases 0.000 description 3
- 230000003321 amplification Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 210000003734 kidney Anatomy 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 239000002398 materia medica Substances 0.000 description 3
- 238000003199 nucleic acid amplification method Methods 0.000 description 3
- 208000026435 phlegm Diseases 0.000 description 3
- KQLDDLUWUFBQHP-UHFFFAOYSA-N Cordycepin Natural products C1=NC=2C(N)=NC=NC=2N1C1OCC(CO)C1O KQLDDLUWUFBQHP-UHFFFAOYSA-N 0.000 description 2
- 241000222336 Ganoderma Species 0.000 description 2
- 235000006439 Lemna minor Nutrition 0.000 description 2
- 244000242291 Lemna paucicostata Species 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000003712 anti-aging effect Effects 0.000 description 2
- 235000009508 confectionery Nutrition 0.000 description 2
- OFEZSBMBBKLLBJ-BAJZRUMYSA-N cordycepin Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)C[C@H]1O OFEZSBMBBKLLBJ-BAJZRUMYSA-N 0.000 description 2
- OFEZSBMBBKLLBJ-UHFFFAOYSA-N cordycepine Natural products C1=NC=2C(N)=NC=NC=2N1C1OC(CO)CC1O OFEZSBMBBKLLBJ-UHFFFAOYSA-N 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 235000013364 duck meat Nutrition 0.000 description 2
- 238000011156 evaluation Methods 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 230000023597 hemostasis Effects 0.000 description 2
- 238000002372 labelling Methods 0.000 description 2
- 230000004060 metabolic process Effects 0.000 description 2
- 231100000252 nontoxic Toxicity 0.000 description 2
- 230000003000 nontoxic effect Effects 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 239000002994 raw material Substances 0.000 description 2
- 230000001256 tonic effect Effects 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- 241000272525 Anas platyrhynchos Species 0.000 description 1
- 235000011201 Ginkgo Nutrition 0.000 description 1
- 244000194101 Ginkgo biloba Species 0.000 description 1
- 235000008100 Ginkgo biloba Nutrition 0.000 description 1
- 235000007710 Grifola frondosa Nutrition 0.000 description 1
- 240000001080 Grifola frondosa Species 0.000 description 1
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000002421 anti-septic effect Effects 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 241000411851 herbal medicine Species 0.000 description 1
- 235000008216 herbs Nutrition 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 229940126680 traditional chinese medicines Drugs 0.000 description 1
Landscapes
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to cordyceps sinensis mycelium oral liquid. The formula of the cordyceps sinensis mycelium oral liquid comprises the following components according to a mass ratio: 80 to 95 percent of cordyceps sinensis mycelium powder extract, 1 to 10 percent of longan extract and 1 to 10 percent of honey. According to the formula disclosed by the invention, any preservative and any colorant are not added, the preparation method is simple, the period is short, the production cost can be effectively controlled, the cordyceps sinensis mycelium oral liquid is safe to take, and the price is reasonable. The cordyceps sinensis mycelium oral liquid is suitable for the requirement of health care of more common people.
Description
Technical field
The present invention relates to a kind of health product, relate in particular to a kind of Cordyceps mycelium oral liquid.
Background technology
Cordyceps is as a kind of traditional Chinese medicines; Be one of famous and precious tonic of China; Medical value to Cordyceps has very high evaluation at all times, and " Bencao Congxin ", supplementary Amplifications of the Compendium of Materia Medica and " Liu Ya compiles outward ", " the little knowledge of Gan Yuan ", " herbal usage studies " etc. are claimed Cordyceps " sweet flat nontoxic ", " protecting the lung kidney tonifying; hemostasis and phlegm ", " controlling weakness ".Modern medicine study shows, contains nutritions such as cordycepic acid, cordycepin and each seed amino acid in the Cordyceps, can promote metabolism, raising immunocompetence, resisting fatigue, the anti-ageing effect of waiting for a long time of human body.Because the output of natural cs is few; Cost an arm and a leg; People begin the artificial culture Cordyceps mycelium gradually and replace Cordyceps sporophore; But the cultivation cycle of the method for preparing complicacy of existing Cordyceps mycelium and bacterial strain is long, and the Chinese caterpillar fungus oral liquid of preparation costs an arm and a leg, and can not satisfy the needs of general public.Cordyceps is one of famous and precious tonic of China; Medical value to Cordyceps has very high evaluation at all times, and " Bencao Congxin ", supplementary Amplifications of the Compendium of Materia Medica and " Liu Ya compiles outward ", " the little knowledge of Gan Yuan ", " herbal usage studies " etc. are claimed Cordyceps " sweet flat nontoxic "; " protect the lung kidney tonifying, hemostasis and phlegm "; " control weakness ".Modern medicine study shows, contains nutritions such as cordycepic acid, cordycepin and each seed amino acid in the Cordyceps, can promote metabolism, raising immunocompetence, resisting fatigue, the anti-ageing effect of waiting for a long time of human body.
One Chinese patent application number is that 92114131.9 patent of invention has disclosed a kind of Chinese caterpillar fungus oral liquid; Particularly a kind of Chinese caterpillar fungus oral liquid that contains old duck meat extracting solution; This invention is converted last about 20% old duck meat extracting solution with the Cordyceps concentrated solution and is mixed with; This method has tangible guarantor's kidney, lung, benefit marrow, functions such as resolving phlegm and relieving asthma with reference to " stewing old duck method " in the supplementary Amplifications of the Compendium of Materia Medica.Chinese patent number is a kind of body-building oral liquid that discloses in the 200610080421.5 patent of invention documents in addition, and synthetic according to a certain ratio potion is fried forms by ten kinds of medical herbs such as Radix Glycyrrhizae, Radix Panacis Quinquefolii, Cordyceps, the system Rhizoma Atractylodis Macrocephalae, Radix Salviae Miltiorrhizae, Poria, Semen Ginkgo, Radix Changii, Arillus Longan, Rhizoma Polygonati Odorati and Mel for it.Chinese patent number is that 200610137751.3 application for a patent for invention discloses a kind of Cordyceps Ganoderma oral liquid in addition; It is filled a prescription as follows: Cordyceps mycelium 40～80%, Ganoderma mycelium 5～15%, maitake mushroom mycelia 4～10%, Cordyceps extract concentrated solution 2～5%, extracts of Chinese herbal medicine 5～15%, agar powder 0.02～0.12%, proper honey, extract of protein and purified water.Adopt the method for preparing that multiple strain ferments simultaneously to process product.Because natural cordyceps output is few, price is very expensive, though the Chinese caterpillar fungus oral liquid that above-mentioned several method is processed has curative effect separately; But its production cost is higher; Particularly second kind with the third oral liquid processing technology in, adopt Chinese caterpilar fungus concentrated solution as raw material, its manufacturing cost is very high; And its technology is complicated, is not suitable for industrial mass production.
Summary of the invention
The technical problem that the present invention will solve is to provide a kind of Cordyceps mycelium oral liquid and preparation method thereof, and its prescription is more reasonable, and method for preparing is simple, the cycle is short, has effectively controlled production cost, reasonable price, suitable most common people's health care demand.
Technical scheme of the present invention: a kind of Cordyceps mycelium oral liquid is characterized in that: its prescription by mass ratio is:
Cordyceps mycelium powder extracting solution 80 ~ 95%;
Arillus Longan extracting solution 1 ~ 10%;
Mel 1 ~ 10%.
The ratio of above-mentioned each component can be preferably:
Cordyceps mycelium powder extracting solution 94 %;
Arillus Longan extracting solution 1 %;
Mel 5 %.
A kind of method for preparing of Cordyceps mycelium oral liquid is characterized in that technological process is:
A) preparation Cordyceps mycelium powder; And extract its active ingredient: Cordyceps mycelium is ground to form powdery; Again Cordyceps mycelium powder is put into and injected quantitative clear water extraction pot; Be warming up to 90 ℃ and keep 90min, when check Main Ingredients and Appearance D-mannitol content reaches about 100mg/L, can stop extraction;
B) filter: obtain Cordyceps mycelium powder filtrating after filtering through flame filter press;
C) concentrate: above-mentioned Cordyceps mycelium powder filtrating concentrates through vacuum concentrator, and check once more is a terminal point with the product standard of its D-mannitol content >=120mg/L, obtains the Cordyceps mycelium powder extracting solution;
D) extraction of Arillus Longan: in extraction pot, inject clear water, Arillus Longan is dropped in the extraction pot, be warming up to 100 ℃, and keep 60min, after filtering, obtain the Arillus Longan extracting solution again;
E) oral liquid compounding: the Cordyceps mycelium powder extracting solution after will concentrating pumps in the material-compound tank, adds Arillus Longan extracting solution, Mel and water, carries out accurate standardize solution, and wherein, the mass ratio of each component is: Cordyceps mycelium powder extracting solution 80 ~ 95%; Arillus Longan extracting solution 1 ~ 10%; Mel 1 ~ 10%; Filter through diatomaceous earth filter again and obtain the Cordyceps mycelium oral liquid, carry out going out finished product behind fill, the high temperature sterilize through after the assay was approved.
Wherein, said autoclaving can be specially: the oral liquid after the fill is got in the high-pressure sterilizing pot, under 121 ℃, keep 40min, take the dish out of the pot after the cooling.
The present invention has following advantage: because the output of natural cs is few; Cost an arm and a leg; The applicant is through for many years experiment; The artificial culture Cordyceps mycelium is replaced the raw material that Cordyceps sporophore is produced as oral liquid, and replace its acute toxicity test of natural cs result to show also have the advantage littler than natural cs toxicity with Cordyceps mycelium; The prescription of the present invention's employing is applicable to most of general populations in addition, and method for preparing is simple, the cycle is short, has effectively controlled production cost; Reasonable price; Can satisfy the health care demand of ordinary consumer, not add any antiseptic, coloring agent in the prescription of the present invention, consumer takes safer.
The specific embodiment
Come the present invention is carried out detailed explanation below in conjunction with specific embodiment.
A kind of Cordyceps mycelium oral liquid, its prescription by mass ratio is:
Cordyceps mycelium powder extracting solution 80 ~ 95%;
Arillus Longan extracting solution 1 ~ 10%;
Mel 1 ~ 10%;
The prescription of a preferred embodiment of the present invention is:
Cordyceps mycelium powder extracting solution 94 %;
Arillus Longan extracting solution 1 %;
Mel 5 %.
To produce the 1000kg oral liquid is example, and the method for preparing of the preferred embodiment is following:
A) active ingredient of extraction Cordyceps mycelium powder (equipment: volume 6T extraction pot): earlier Cordyceps mycelium is ground to form powdery; In extraction pot, quantitatively inject 1100 L clear water; Cordyceps mycelium powder 50kg is put in the extraction pot; Be warming up to 90 ℃ and keep 90min, when check Main Ingredients and Appearance D-mannitol content reaches about 100mg/L, can stop extraction;
B) filter (equipment: 30 ㎡ filter press): filter (the about 1000kg of the amount that must filtrate) through flame filter press;
C) concentrate (1T/h concentration kettle): filtrating concentrates through the 1T/h vacuum concentrator, and check once more is a terminal point with the product standard of its D-mannitol content >=120mg/L, (concentrated solution must be measured about 910kg);
D) method for distilling of Arillus Longan: in the extraction pot of 500L, inject the 50L clear water, Arillus Longan 10kg dropped in the extraction pot, be warming up to 100 ℃, and keep 60min, filter, filtrate the about 40kg of amount;
E) preparation (equipment: the material-compound tank of volume 6T,, 2 ㎡ diatomaceous earth filters): the extracting solution 910kg after will concentrating pumps in the material-compound tank, adds Arillus Longan extracting solution 40kg; Mel 50kg; Accurate standardize solution filters through diatomaceous earth filter at 1000kg, and filtrating is sent the laboratory check at last;
F) standardize solution:, therefore, need at last to confirm that by the proportioning of above-mentioned each component preparation capacity, the purpose of standardize solution are exactly that to guarantee that production technology prescription and this product effective ingredient are preset accurate because mycopowder and Arillus Longan will lose part moisture when extracting;
G) fill (equipment: 6T receiver; The full-automatic filling production lines of 1000 bottles/h): significant index reaches after the product standard to be delivered to racking room by infusion pump and gets into automatic loading production line and carry out fill;
H) (equipment: 4 cubes of high-pressure sterilizing pots): the oral liquid after the fill gets in the high-pressure sterilizing pot autoclaving, under 121 ℃, keeps 40min, takes the dish out of the pot after the cooling;
I) check (equipment: the lamp inspection machine): the oral liquid after taking the dish out of the pot is pursued a bottle lamp inspection;
Packing (equipment: labelling machine): get into labelling machine behind the lamp inspection and pack end product.
Claims (4)
1. Cordyceps mycelium oral liquid, it is characterized in that: its prescription by mass ratio is:
Cordyceps mycelium powder extracting solution 80 ~ 95%;
Arillus Longan extracting solution 1 ~ 10%;
Mel 1 ~ 10%.
2. Cordyceps mycelium oral liquid according to claim 1 is characterized in that: its formula optimization is:
Cordyceps mycelium powder extracting solution 94 %;
Arillus Longan extracting solution 1 %;
Mel 5 %.
3. method for preparing the described Cordyceps mycelium oral liquid of claim 1, it is characterized in that: its technological process is:
A) preparation Cordyceps mycelium powder; And extract its active ingredient: Cordyceps mycelium is ground to form powdery; Again Cordyceps mycelium powder is put into and injected quantitative clear water extraction pot; Be warming up to 90 ℃ and kept 90 minutes, when check Main Ingredients and Appearance D-mannitol content reaches about 100mg/L, can stop extraction;
B) filter: obtain the Cordyceps mycelium powder extracting solution after filtering through flame filter press;
C) concentrate: above-mentioned Cordyceps mycelium powder extracting solution is concentrated through vacuum concentrator, and check once more is a terminal point with the product standard of its D-mannitol content >=120mg/L, obtains the Cordyceps mycelium powder concentrated solution;
D) extraction of Arillus Longan: in extraction pot, inject clear water, Arillus Longan is dropped in the extraction pot, be warming up to 100 ℃, and keep 60min, after filtering, obtain the Arillus Longan extracting solution again;
E) oral liquid compounding: the Cordyceps mycelium powder concentrated solution after will concentrating pumps in the material-compound tank; Add Arillus Longan extracting solution, Mel and water; Proportion requirement according to each component is carried out accurate standardize solution, and wherein each component is specially by mass ratio: Cordyceps mycelium powder extracting solution 80 ~ 95%; Arillus Longan extracting solution 1 ~ 10%; Mel 1 ~ 10%; Filter through diatomaceous earth filter again and obtain the Cordyceps mycelium oral liquid, carry out going out finished product behind fill, the high temperature sterilize through after the assay was approved.
4. the manufacturing approach of Cordyceps mycelium oral liquid according to claim 3 is characterized in that: said autoclaving can be specially: the oral liquid after the fill is got in the high-pressure sterilizing pot, under 121 ℃, kept 40 minutes, take the dish out of the pot after the cooling.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210138729.6A CN102670715B (en) | 2012-05-08 | 2012-05-08 | Cordyceps sinensis mycelium oral liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210138729.6A CN102670715B (en) | 2012-05-08 | 2012-05-08 | Cordyceps sinensis mycelium oral liquid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN102670715A true CN102670715A (en) | 2012-09-19 |
| CN102670715B CN102670715B (en) | 2014-02-26 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201210138729.6A Active CN102670715B (en) | 2012-05-08 | 2012-05-08 | Cordyceps sinensis mycelium oral liquid |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103238712A (en) * | 2013-05-20 | 2013-08-14 | 北京绿源求证科技发展有限责任公司 | Anti-aging food health tea electuary |
| CN103520364A (en) * | 2013-09-05 | 2014-01-22 | 上海其易融生物技术有限公司 | Compound medicinal composition of cordyceps mycelia and preparation method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1145740A (en) * | 1995-09-22 | 1997-03-26 | 贤英越 | Longan paste |
| CN101104006A (en) * | 2007-08-13 | 2008-01-16 | 叶天任 | Method for preparing Chinese caterpillar fungus extracting concentrated liquid and application thereof |
-
2012
- 2012-05-08 CN CN201210138729.6A patent/CN102670715B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1145740A (en) * | 1995-09-22 | 1997-03-26 | 贤英越 | Longan paste |
| CN101104006A (en) * | 2007-08-13 | 2008-01-16 | 叶天任 | Method for preparing Chinese caterpillar fungus extracting concentrated liquid and application thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103238712A (en) * | 2013-05-20 | 2013-08-14 | 北京绿源求证科技发展有限责任公司 | Anti-aging food health tea electuary |
| CN103520364A (en) * | 2013-09-05 | 2014-01-22 | 上海其易融生物技术有限公司 | Compound medicinal composition of cordyceps mycelia and preparation method thereof |
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| Publication number | Publication date |
|---|---|
| CN102670715B (en) | 2014-02-26 |
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Denomination of invention: Cordyceps sinensis mycelium oral liquid Effective date of registration: 20230111 Granted publication date: 20140226 Pledgee: Agricultural Bank of China Limited by Share Ltd. Shunchang branch Pledgor: FUJIAN RUNXING BIOLOGICAL TECHNOLOGY Co.,Ltd. Registration number: Y2023350000013 |