CN102666867A - 使用添加渗透物的萃取发酵生产丁醇的方法 - Google Patents

使用添加渗透物的萃取发酵生产丁醇的方法 Download PDF

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Publication number
CN102666867A
CN102666867A CN201080052282XA CN201080052282A CN102666867A CN 102666867 A CN102666867 A CN 102666867A CN 201080052282X A CN201080052282X A CN 201080052282XA CN 201080052282 A CN201080052282 A CN 201080052282A CN 102666867 A CN102666867 A CN 102666867A
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butanol
butanols
permeate
extractant
phase
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English (en)
Chinese (zh)
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R·帕特奈克
M·C·格拉迪
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Butamax Advanced Biofuels LLC
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Butamax Advanced Biofuels LLC
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/16—Butanols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/74—Separation; Purification; Use of additives, e.g. for stabilisation
    • C07C29/76—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment
    • C07C29/86—Separation; Purification; Use of additives, e.g. for stabilisation by physical treatment by liquid-liquid treatment
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/26—Processes using, or culture media containing, hydrocarbons
    • C12N1/28—Processes using, or culture media containing, hydrocarbons aliphatic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00—Technologies for the production of fuel of non-fossil origin
    • Y02E50/10—Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN201080052282XA 2009-11-23 2010-11-23 使用添加渗透物的萃取发酵生产丁醇的方法 Pending CN102666867A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US26352209P 2009-11-23 2009-11-23
US61/263,522 2009-11-23
PCT/US2010/057846 WO2011063402A2 (en) 2009-11-23 2010-11-23 Method for producing butanol using extractive fermentation with osmolyte addition

Publications (1)

Publication Number Publication Date
CN102666867A true CN102666867A (zh) 2012-09-12

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CN201080052282XA Pending CN102666867A (zh) 2009-11-23 2010-11-23 使用添加渗透物的萃取发酵生产丁醇的方法

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Country Link
US (1) US20110136193A1 (enExample)
EP (1) EP2504447A2 (enExample)
JP (1) JP2013511284A (enExample)
KR (1) KR20120117990A (enExample)
CN (1) CN102666867A (enExample)
AU (1) AU2010321575A1 (enExample)
BR (1) BR112012012211A2 (enExample)
CA (1) CA2779460A1 (enExample)
IN (1) IN2012DN03327A (enExample)
MX (1) MX2012005910A (enExample)
NZ (1) NZ599415A (enExample)
WO (1) WO2011063402A2 (enExample)
ZA (1) ZA201203652B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105713823A (zh) * 2016-03-25 2016-06-29 华南理工大学 一种萃取发酵生产异丙醇和丁醇的装置和方法
CN109536397A (zh) * 2018-12-03 2019-03-29 上海交通大学 一种基因工程酿酒酵母及其制备方法和应用
WO2024255690A1 (zh) * 2023-06-13 2024-12-19 浙江工业大学 一种产d-泛酸的基因工程菌、构建方法及应用

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BRPI0909989A2 (pt) 2008-06-05 2021-06-22 Butamax Advanced Biofuels Llc célula de levedura recombinante e método para a produção de um produto
BRPI0913682A2 (pt) * 2008-09-29 2020-08-11 Butamax Advanced Biofuels Llc método para identificar enzimas dihidróxi-ácido desidratase (dhad) [2fe-2s], célula hospedeira microbiana recombinante, método para a produção de isobutanol e método para a conversão de 2,3-dihidróxiisovalerato
JP5804946B2 (ja) 2008-09-29 2015-11-04 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー 酵母における異種性Ｆｅ−Ｓ酵素活性の増大
AU2011218090B2 (en) 2010-02-17 2016-06-23 Butamax(Tm) Advanced Biofuels Llc Improving activity of Fe-S cluster requiring proteins
AU2011268215B2 (en) * 2010-06-18 2014-10-23 Butamax(Tm) Advanced Biofuels Llc Supplementation of fatty acids for improving alcohol productivity
AU2011268220B2 (en) 2010-06-18 2015-01-29 Butamax(Tm) Advanced Biofuels Llc Extraction solvents derived from oil for alcohol removal in extractive fermentation
US8765425B2 (en) * 2011-03-23 2014-07-01 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
JP2014509869A (ja) * 2011-03-23 2014-04-24 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー 発酵におけるアルコールエステルの酵素的生産のためのリパーゼの原位置発現
US8759044B2 (en) 2011-03-23 2014-06-24 Butamax Advanced Biofuels Llc In situ expression of lipase for enzymatic production of alcohol esters during fermentation
CN102356899B (zh) * 2011-09-07 2012-11-28 中国食品发酵工业研究院 一种天然果蔬酵素饮料及其制备方法
US9962623B2 (en) 2011-12-09 2018-05-08 Butamax Advanced Biofuels Llc Process to remove product alcohols from fermentation broth
AU2012362274A1 (en) 2011-12-30 2014-07-03 Butamax (Tm) Advanced Biofuels Llc Fermentative production of alcohols
CN104284981A (zh) 2012-03-23 2015-01-14 布特马斯先进生物燃料有限责任公司 在针对产丁醇生物的培养基中补充乙酸盐
WO2013148289A1 (en) * 2012-03-30 2013-10-03 Hydration Systems, Llc Use of novel draw solutes and combinations in forward osmosis system
KR20150007329A (ko) 2012-05-04 2015-01-20 부타맥스 어드밴스드 바이오퓨얼스 엘엘씨 알코올 생산 및 회수를 위한 공정 및 시스템
US9605281B2 (en) 2012-09-12 2017-03-28 Butamax Advanced Biofuels Llc Processes and systems for the fermentative production of alcohols
WO2014018837A1 (en) 2012-07-26 2014-01-30 Cheng Cecilia Butanol purification
CN102787144B (zh) * 2012-07-27 2013-10-16 中国科学院过程工程研究所 一种生物质发酵-渗透汽化膜耦合生产丙酮丁醇的工艺
US9109196B2 (en) 2012-09-12 2015-08-18 Butamax Advanced Biofuels Llc Processes and systems for the production of fermentation products
CA2885427A1 (en) 2012-09-21 2014-03-27 Butamax Advanced Biofuels Llc A method for producing butanol using two-phase extractive fermentation and recyclable extractant compositions
US20140093931A1 (en) 2012-09-28 2014-04-03 Butamax Advanced Biofuels Llc Production of fermentation products
US9650624B2 (en) 2012-12-28 2017-05-16 Butamax Advanced Biofuels Llc DHAD variants for butanol production
WO2014105840A1 (en) 2012-12-31 2014-07-03 Butamax Advanced Biofuels Llc Fermentative production of alcohols
US9523104B2 (en) 2013-03-12 2016-12-20 Butamax Advanced Biofuels Llc Processes and systems for the production of alcohols
US9469584B2 (en) 2013-03-15 2016-10-18 Butamax Advanced Biofuels Llc Method for producing butanol using extractive fermentation
WO2014144728A1 (en) 2013-03-15 2014-09-18 Butamax Advanced Biofuels Llc Method for production of butanol using extractive fermentation
WO2014151190A1 (en) 2013-03-15 2014-09-25 Butamax Advanced Biofuels Llc Dhad variants and methods of screening
US9771602B2 (en) 2013-03-15 2017-09-26 Butamax Advanced Biofuels Llc Competitive growth and/or production advantage for butanologen microorganism
EP3114103A4 (en) * 2014-03-04 2018-01-17 White Dog Labs, Inc. Energy efficient batch recycle method for the production of biomolecules
EP3129116A4 (en) 2014-04-11 2018-02-14 Butamax Advanced Biofuels LLC Contamination mitigation
EP3277652A4 (en) * 2015-03-31 2018-11-07 White Dog Labs, Inc. Method of producing bioproducts
WO2016160817A1 (en) * 2015-03-31 2016-10-06 White Dog Labs, Inc. Method of producing bioproducts
JP7738417B2 (ja) * 2021-07-08 2025-09-12 日鉄エンジニアリング株式会社 連続抽出発酵装置及び連続抽出発酵方法
EP4536615A1 (en) * 2022-06-10 2025-04-16 Amyris, Inc. Compositions and methods for improved cell culture efficiency

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BRPI0909989A2 (pt) * 2008-06-05 2021-06-22 Butamax Advanced Biofuels Llc célula de levedura recombinante e método para a produção de um produto
JP5804946B2 (ja) * 2008-09-29 2015-11-04 ビュータマックス・アドバンスド・バイオフューエルズ・エルエルシー 酵母における異種性Ｆｅ−Ｓ酵素活性の増大
BRPI0913682A2 (pt) 2008-09-29 2020-08-11 Butamax Advanced Biofuels Llc método para identificar enzimas dihidróxi-ácido desidratase (dhad) [2fe-2s], célula hospedeira microbiana recombinante, método para a produção de isobutanol e método para a conversão de 2,3-dihidróxiisovalerato
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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105713823A (zh) * 2016-03-25 2016-06-29 华南理工大学 一种萃取发酵生产异丙醇和丁醇的装置和方法
CN109536397A (zh) * 2018-12-03 2019-03-29 上海交通大学 一种基因工程酿酒酵母及其制备方法和应用
WO2024255690A1 (zh) * 2023-06-13 2024-12-19 浙江工业大学 一种产d-泛酸的基因工程菌、构建方法及应用

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Publication number Publication date
ZA201203652B (en) 2013-08-28
MX2012005910A (es) 2012-06-19
NZ599415A (en) 2014-06-27
IN2012DN03327A (enExample) 2015-10-23
WO2011063402A2 (en) 2011-05-26
KR20120117990A (ko) 2012-10-25
WO2011063402A3 (en) 2011-10-13
JP2013511284A (ja) 2013-04-04
US20110136193A1 (en) 2011-06-09
BR112012012211A2 (pt) 2017-05-09
CA2779460A1 (en) 2011-05-26
EP2504447A2 (en) 2012-10-03
AU2010321575A1 (en) 2012-05-10

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Application publication date: 20120912