CN102648044B - 用于培养细胞和/或微生物的装置 - Google Patents

用于培养细胞和/或微生物的装置 Download PDF

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Publication number
CN102648044B
CN102648044B CN200980160392.5A CN200980160392A CN102648044B CN 102648044 B CN102648044 B CN 102648044B CN 200980160392 A CN200980160392 A CN 200980160392A CN 102648044 B CN102648044 B CN 102648044B
Authority
CN
China
Prior art keywords
reactor
container
arched
liquid
wall
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN200980160392.5A
Other languages
English (en)
Chinese (zh)
Other versions
CN102648044A (zh
Inventor
J·考林
B·莫伊泽
A·布劳恩
S·肖森
W·卡勒特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Bayer Technology Services GmbH
Bayer Intellectual Property GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Technology Services GmbH, Bayer Intellectual Property GmbH filed Critical Bayer Technology Services GmbH
Publication of CN102648044A publication Critical patent/CN102648044A/zh
Application granted granted Critical
Publication of CN102648044B publication Critical patent/CN102648044B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/28—Moving reactors, e.g. rotary drums
    • B01J19/285—Shaking or vibrating reactors; reactions under the influence of low-frequency vibrations or pulsations
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/28—Moving reactors, e.g. rotary drums
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/10—Mixers with shaking, oscillating, or vibrating mechanisms with a mixing receptacle rotating alternately in opposite directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/50—Mixing receptacles
    • B01F35/53—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J15/00—Chemical processes in general for reacting gaseous media with non-particulate solids, e.g. sheet material; Apparatus specially adapted therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/26—Constructional details, e.g. recesses, hinges flexible
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/10—Rotating vessel
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
    • G06K19/00—Record carriers for use with machines and with at least a part designed to carry digital markings
    • G06K19/06—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
    • G06K19/067—Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards also with resonating or responding marks without active components
    • G06K19/07—Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards also with resonating or responding marks without active components with integrated circuit chips
    • G06K19/0716—Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards also with resonating or responding marks without active components with integrated circuit chips at least one of the integrated circuit chips comprising a sensor or an interface to a sensor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • General Engineering & Computer Science (AREA)
  • Microelectronics & Electronic Packaging (AREA)
  • Computer Hardware Design (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Clinical Laboratory Science (AREA)
  • Theoretical Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
CN200980160392.5A 2009-05-05 2009-12-03 用于培养细胞和/或微生物的装置 Expired - Fee Related CN102648044B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102009019697A DE102009019697A1 (de) 2009-05-05 2009-05-05 Container
DE102009019697.8 2009-05-05
PCT/EP2009/008616 WO2010127689A1 (de) 2009-05-05 2009-12-03 Vorrichtung zur kultivierung von zellen und/oder mikroorganismen

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2013100128250A Division CN103084136A (zh) 2009-05-05 2009-12-03 用于培养细胞和/或微生物的装置

Publications (2)

Publication Number Publication Date
CN102648044A CN102648044A (zh) 2012-08-22
CN102648044B true CN102648044B (zh) 2015-02-11

Family

ID=42115132

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2013100128250A Pending CN103084136A (zh) 2009-05-05 2009-12-03 用于培养细胞和/或微生物的装置
CN200980160392.5A Expired - Fee Related CN102648044B (zh) 2009-05-05 2009-12-03 用于培养细胞和/或微生物的装置

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CN2013100128250A Pending CN103084136A (zh) 2009-05-05 2009-12-03 用于培养细胞和/或微生物的装置

Country Status (10)

Country Link
US (1) US20120100605A1 (enExample)
EP (2) EP2427268A1 (enExample)
JP (1) JP5730858B2 (enExample)
KR (1) KR20120026078A (enExample)
CN (2) CN103084136A (enExample)
AU (1) AU2009345653A1 (enExample)
CA (1) CA2760728A1 (enExample)
DE (1) DE102009019697A1 (enExample)
SG (2) SG10201401999SA (enExample)
WO (1) WO2010127689A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012125730A2 (en) * 2011-03-15 2012-09-20 Abec, Inc. Reactor systems
WO2013137812A1 (en) 2012-03-16 2013-09-19 Ge Healthcare Bio-Sciences Ab Mixing system
GB201213506D0 (en) * 2012-07-30 2012-09-12 Tap Biosystems Phc Ltd Bioreactor vessels and associated bioreactor systems
CN104812888A (zh) * 2012-09-18 2015-07-29 拜耳技术服务有限公司 一次性瓶式反应罐
US10076753B2 (en) 2013-06-12 2018-09-18 Ge Healthcare Bio-Sciences Corp. Disposable container and mixing system comprising the container
DK3825394T3 (da) 2013-12-10 2024-01-15 Abec Inc Engangsbeholder omfattende et forseglingsarrangement samt anvendelse deraf
DE102014105472B4 (de) * 2014-04-16 2016-03-17 Sartorius Stedim Biotech Gmbh Misch- und Auftauvorrichtung
JP6712999B2 (ja) * 2014-12-16 2020-06-24 セルダイナミクス アイ エス アール エル 流体中の懸濁粒子のリアルタイム分析装置および該粒子の分析方法
CN104492291B (zh) * 2014-12-18 2023-04-25 重庆康乐制药有限公司 便于更换的乳化反应装置
WO2016137231A1 (ko) * 2015-02-28 2016-09-01 김두현 바이오리액터의 일회용 컨테이너
US10857510B2 (en) 2015-04-16 2020-12-08 Global Life Sciences Solutions Usa Llc Bioprocess mixer
EP3475412A4 (en) * 2016-04-12 2020-03-18 Thrive Bioscience, Inc. CELL CULTURE CONTAINER
US11359172B2 (en) * 2017-08-09 2022-06-14 Sartorius Stedim Biotech Gmbh Upstream and downstream processing within single-use containers
AU2018346876B2 (en) 2017-10-03 2024-07-11 Abec Inc. Reactor systems
CN108641915A (zh) * 2018-06-06 2018-10-12 佛山科学技术学院 一种适用于摇瓶培养的箱体结构

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005049785A1 (en) * 2003-11-18 2005-06-02 Nestec S.A. Cell culture system
WO2007121958A1 (de) * 2006-04-22 2007-11-01 Bayer Technology Services Gmbh Reaktor
EP1923459A1 (en) * 2006-11-15 2008-05-21 Millipore Corporation A bioreactor
CN201206148Y (zh) * 2008-03-07 2009-03-11 医健有限公司 生物细胞培植装置

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4412627A (en) * 1981-05-29 1983-11-01 Metal Container Corporation Drawn and ironed can body
FI86601C (fi) * 1987-10-21 1992-09-25 Outokumpu Oy Saett att aostadkomma dubbelcirkulationsfloede och apparatur daertill.
FR2781202B1 (fr) * 1998-07-16 2001-01-12 Stedim Sa Poches pour produits fluides bio-pharmaceutiques
US7153021B2 (en) * 2003-03-28 2006-12-26 Hyclone Laboratories, Inc. Container systems for mixing fluids with a magnetic stir bar
CA2569405C (en) * 2004-06-04 2011-05-03 Xcellerex, Inc. Disposable bioreactor systems and methods
CA2605599A1 (en) * 2005-04-22 2006-11-02 Hyclone Laboratories, Inc. Tube ports and related container systems
SG176507A1 (en) * 2006-05-13 2011-12-29 Advanced Tech Materials Disposable bioreactor
US20080131959A1 (en) * 2006-11-15 2008-06-05 Millipore Corporation Bioreactor construction

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005049785A1 (en) * 2003-11-18 2005-06-02 Nestec S.A. Cell culture system
WO2007121958A1 (de) * 2006-04-22 2007-11-01 Bayer Technology Services Gmbh Reaktor
EP1923459A1 (en) * 2006-11-15 2008-05-21 Millipore Corporation A bioreactor
CN201206148Y (zh) * 2008-03-07 2009-03-11 医健有限公司 生物细胞培植装置

Also Published As

Publication number Publication date
CN102648044A (zh) 2012-08-22
EP2517786A2 (de) 2012-10-31
WO2010127689A1 (de) 2010-11-11
KR20120026078A (ko) 2012-03-16
US20120100605A1 (en) 2012-04-26
DE102009019697A1 (de) 2010-11-18
EP2427268A1 (de) 2012-03-14
CA2760728A1 (en) 2010-11-11
SG10201401999SA (en) 2014-07-30
AU2009345653A1 (en) 2011-12-08
EP2517786A3 (de) 2016-03-16
JP5730858B2 (ja) 2015-06-10
SG175806A1 (en) 2011-12-29
JP2012525822A (ja) 2012-10-25
CN103084136A (zh) 2013-05-08

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C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: BAYER INTELLECTUAL PROPERTY GMBH

Free format text: FORMER OWNER: BAYER AG

Effective date: 20130807

C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20130807

Address after: German Monheim

Applicant after: Bayer Pharma Aktiengesellschaft

Address before: Germany Leverkusen

Applicant before: Bayer Ag

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GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20150211

Termination date: 20151203

EXPY Termination of patent right or utility model