JP5730858B2 - 細胞および/または微生物を培養するための装置 - Google Patents
細胞および/または微生物を培養するための装置 Download PDFInfo
- Publication number
- JP5730858B2 JP5730858B2 JP2012508899A JP2012508899A JP5730858B2 JP 5730858 B2 JP5730858 B2 JP 5730858B2 JP 2012508899 A JP2012508899 A JP 2012508899A JP 2012508899 A JP2012508899 A JP 2012508899A JP 5730858 B2 JP5730858 B2 JP 5730858B2
- Authority
- JP
- Japan
- Prior art keywords
- reactor
- container
- floor
- wall
- internal space
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/28—Moving reactors, e.g. rotary drums
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/28—Moving reactors, e.g. rotary drums
- B01J19/285—Shaking or vibrating reactors; reactions under the influence of low-frequency vibrations or pulsations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
- B01F31/10—Mixers with shaking, oscillating, or vibrating mechanisms with a mixing receptacle rotating alternately in opposite directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/50—Mixing receptacles
- B01F35/53—Mixing receptacles characterised by the configuration of the interior, e.g. baffles for facilitating the mixing of components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J15/00—Chemical processes in general for reacting gaseous media with non-particulate solids, e.g. sheet material; Apparatus specially adapted therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/26—Constructional details, e.g. recesses, hinges flexible
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
- C12M27/10—Rotating vessel
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
- G06K19/00—Record carriers for use with machines and with at least a part designed to carry digital markings
- G06K19/06—Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
- G06K19/067—Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards also with resonating or responding marks without active components
- G06K19/07—Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards also with resonating or responding marks without active components with integrated circuit chips
- G06K19/0716—Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards also with resonating or responding marks without active components with integrated circuit chips at least one of the integrated circuit chips comprising a sensor or an interface to a sensor
Landscapes
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Computer Hardware Design (AREA)
- Microelectronics & Electronic Packaging (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Theoretical Computer Science (AREA)
- Clinical Laboratory Science (AREA)
- Medicinal Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Description
反応器を収容する内部空間と、
上記容器内へ反応器を正面から導入するための開口とを備え、
上記開口は、閉じられうると共に、上記閉状態で液密されるように設計されており、
上記容器の上記内部空間内へ内側に曲がった床と、
側部チャンネルとを備え、
この側部チャンネルを介して、ホースおよび/またはチャンネルおよび/または計測プローブが、上記反応器につながれうる。
したがって、このことは、カップリングにおける漏れの結果として反応器が完全に排出するのを確実に避ける。したがって、周囲からのラインの付加的な保護は、要求されない。
2 駆動装置
3 床板
5 容器壁
20 内側に曲がった床
30 側部チャンネル
34 チャンネル壁
35 チャンネル壁
40 内部空間
50 接続板
52 接続部
55 ガス分配器
60 通路/接続
80 気泡
90 ガス噴流
100 反応器
200 閉鎖装置
201 制御ユニット
205 ドア
210 フレーム
300 ガス供給口
301 ガス噴流
305 ヘッドスペース
310 液体レベル
320 ガス除去
401 フィルム部品
402 フィルム部品
401 フィルム部品
402 フィルム部品
405 長手側の溶接継ぎ目
406 角部の溶接継ぎ目
Claims (2)
- 内部空間を囲む壁と、この壁における通過部および/または接続部とを備え、上記内部空間を外部環境につなぐのを許容し、
液体で満たされたとき、上記液体の表面と平行な角断面と、上記内部空間内に曲がった、または曲げられうる床とを有し、
上記内部空間に曲がった床は、上記反応器の上記内部空間内に突出する縁を有し、
上記床の円相当直径dに対する上記床の湾曲の高さhの比は、3%から100%までの範囲内にある反応器を収容する容器であって、少なくとも、
上記反応器を収容する内部空間と、
上記容器内へ上記反応器を正面から導入するための開口とを備え、
上記開口は、閉じられうると共に、上記閉状態で液密であるように設計されており、
上記容器の上記内部空間内へ内側に曲がった床と、
側部チャンネルとを備え、
この側部チャンネルを介して、ホースとチャンネルとが、上記反応器につながれることができ、
上記内側に曲がった床は、ピラミッド構造の多面体であり、
上記側部チャンネルは、2つの間隔をおいた壁の間に延在し、
上記壁は、使い捨ての上記反応器の床部に達し、上記壁は、上記容器内へ上記反応器を正面から導入するために取り外し可能となっていることを特徴とする容器。 - 請求項1に記載の容器において、
さらに加熱および/または冷却要素を備え、この要素は、上記容器の壁の中および/または壁の上に取り付けられることを特徴とする容器。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102009019697.8 | 2009-05-05 | ||
DE102009019697A DE102009019697A1 (de) | 2009-05-05 | 2009-05-05 | Container |
PCT/EP2009/008616 WO2010127689A1 (de) | 2009-05-05 | 2009-12-03 | Vorrichtung zur kultivierung von zellen und/oder mikroorganismen |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2012525822A JP2012525822A (ja) | 2012-10-25 |
JP2012525822A5 JP2012525822A5 (ja) | 2012-12-06 |
JP5730858B2 true JP5730858B2 (ja) | 2015-06-10 |
Family
ID=42115132
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2012508899A Expired - Fee Related JP5730858B2 (ja) | 2009-05-05 | 2009-12-03 | 細胞および/または微生物を培養するための装置 |
Country Status (10)
Country | Link |
---|---|
US (1) | US20120100605A1 (ja) |
EP (2) | EP2517786A3 (ja) |
JP (1) | JP5730858B2 (ja) |
KR (1) | KR20120026078A (ja) |
CN (2) | CN102648044B (ja) |
AU (1) | AU2009345653A1 (ja) |
CA (1) | CA2760728A1 (ja) |
DE (1) | DE102009019697A1 (ja) |
SG (2) | SG10201401999SA (ja) |
WO (1) | WO2010127689A1 (ja) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102126642B1 (ko) * | 2011-03-15 | 2020-06-26 | 아벡, 아이엔씨. | 반응기 시스템 |
WO2013137812A1 (en) | 2012-03-16 | 2013-09-19 | Ge Healthcare Bio-Sciences Ab | Mixing system |
GB201213506D0 (en) * | 2012-07-30 | 2012-09-12 | Tap Biosystems Phc Ltd | Bioreactor vessels and associated bioreactor systems |
AU2013320374A1 (en) | 2012-09-18 | 2015-03-26 | Bayer Technology Services Gmbh | Disposable bottle reactor tank |
US10076753B2 (en) * | 2013-06-12 | 2018-09-18 | Ge Healthcare Bio-Sciences Corp. | Disposable container and mixing system comprising the container |
DK3825394T3 (da) | 2013-12-10 | 2024-01-15 | Abec Inc | Engangsbeholder omfattende et forseglingsarrangement samt anvendelse deraf |
DE102014105472B4 (de) * | 2014-04-16 | 2016-03-17 | Sartorius Stedim Biotech Gmbh | Misch- und Auftauvorrichtung |
WO2016098011A1 (en) * | 2014-12-16 | 2016-06-23 | Celldynamics I.S.R.L. | Device for real time analysis of particles suspended in a fluid and method for the analysis of said particles |
CN104492291B (zh) * | 2014-12-18 | 2023-04-25 | 重庆康乐制药有限公司 | 便于更换的乳化反应装置 |
WO2016137231A1 (ko) * | 2015-02-28 | 2016-09-01 | 김두현 | 바이오리액터의 일회용 컨테이너 |
JP6797417B2 (ja) | 2015-04-16 | 2020-12-09 | グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー | バイオプロセスミキサー |
EP3475412A4 (en) * | 2016-04-12 | 2020-03-18 | Thrive Bioscience, Inc. | CELL CULTURE CONTAINER |
US11359172B2 (en) * | 2017-08-09 | 2022-06-14 | Sartorius Stedim Biotech Gmbh | Upstream and downstream processing within single-use containers |
EP3691781A4 (en) | 2017-10-03 | 2021-01-20 | Abec, Inc. | REACTOR SYSTEMS |
CN108641915A (zh) * | 2018-06-06 | 2018-10-12 | 佛山科学技术学院 | 一种适用于摇瓶培养的箱体结构 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4412627A (en) * | 1981-05-29 | 1983-11-01 | Metal Container Corporation | Drawn and ironed can body |
FI86601C (fi) * | 1987-10-21 | 1992-09-25 | Outokumpu Oy | Saett att aostadkomma dubbelcirkulationsfloede och apparatur daertill. |
FR2781202B1 (fr) * | 1998-07-16 | 2001-01-12 | Stedim Sa | Poches pour produits fluides bio-pharmaceutiques |
US7153021B2 (en) * | 2003-03-28 | 2006-12-26 | Hyclone Laboratories, Inc. | Container systems for mixing fluids with a magnetic stir bar |
MXPA06005542A (es) * | 2003-11-18 | 2006-08-23 | Nestec Sa | Sistema de cultivo de celulas. |
DK1773976T4 (da) * | 2004-06-04 | 2020-02-10 | Global Life Sciences Solutions Usa Llc | Engangsbioreaktorsystemer og -fremgangsmåder |
EP1872042B1 (en) * | 2005-04-22 | 2019-12-18 | Life Technologies Corporation | Tube ports and related container systems |
DE102006018824A1 (de) | 2006-04-22 | 2007-10-25 | Bayer Technology Services Gmbh | Einweg-Bioreaktor |
EP2018416B1 (en) * | 2006-05-13 | 2018-10-24 | Pall Life Sciences Belgium | Disposable bioreactor |
US20080131959A1 (en) * | 2006-11-15 | 2008-06-05 | Millipore Corporation | Bioreactor construction |
US20080131960A1 (en) * | 2006-11-15 | 2008-06-05 | Millipore Corporation | Self standing bioreactor construction |
CN201206148Y (zh) * | 2008-03-07 | 2009-03-11 | 医健有限公司 | 生物细胞培植装置 |
-
2009
- 2009-05-05 DE DE102009019697A patent/DE102009019697A1/de not_active Withdrawn
- 2009-12-03 EP EP12176531.7A patent/EP2517786A3/de not_active Withdrawn
- 2009-12-03 CN CN200980160392.5A patent/CN102648044B/zh not_active Expired - Fee Related
- 2009-12-03 KR KR1020117028894A patent/KR20120026078A/ko not_active Application Discontinuation
- 2009-12-03 CN CN2013100128250A patent/CN103084136A/zh active Pending
- 2009-12-03 EP EP09764729A patent/EP2427268A1/de not_active Withdrawn
- 2009-12-03 JP JP2012508899A patent/JP5730858B2/ja not_active Expired - Fee Related
- 2009-12-03 US US13/318,660 patent/US20120100605A1/en not_active Abandoned
- 2009-12-03 CA CA2760728A patent/CA2760728A1/en not_active Abandoned
- 2009-12-03 WO PCT/EP2009/008616 patent/WO2010127689A1/de active Application Filing
- 2009-12-03 SG SG10201401999SA patent/SG10201401999SA/en unknown
- 2009-12-03 SG SG2011078888A patent/SG175806A1/en unknown
- 2009-12-03 AU AU2009345653A patent/AU2009345653A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE102009019697A1 (de) | 2010-11-18 |
SG10201401999SA (en) | 2014-07-30 |
AU2009345653A1 (en) | 2011-12-08 |
EP2427268A1 (de) | 2012-03-14 |
US20120100605A1 (en) | 2012-04-26 |
CN102648044B (zh) | 2015-02-11 |
KR20120026078A (ko) | 2012-03-16 |
CN103084136A (zh) | 2013-05-08 |
JP2012525822A (ja) | 2012-10-25 |
CN102648044A (zh) | 2012-08-22 |
EP2517786A2 (de) | 2012-10-31 |
EP2517786A3 (de) | 2016-03-16 |
CA2760728A1 (en) | 2010-11-11 |
WO2010127689A1 (de) | 2010-11-11 |
SG175806A1 (en) | 2011-12-29 |
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