CN102648015B - 施加到皮肤的较小装置、模块化系统及其使用方法 - Google Patents

施加到皮肤的较小装置、模块化系统及其使用方法 Download PDF

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Publication number
CN102648015B
CN102648015B CN201080055393.6A CN201080055393A CN102648015B CN 102648015 B CN102648015 B CN 102648015B CN 201080055393 A CN201080055393 A CN 201080055393A CN 102648015 B CN102648015 B CN 102648015B
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China
Prior art keywords
skin
subject
fluid
extraction
self
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Expired - Fee Related
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CN201080055393.6A
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English (en)
Chinese (zh)
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CN102648015A (zh
Inventor
H·伯恩斯坦
D·E·奇克林
D·A·莱文森
D·R·瓦尔特
S·戴维斯
R·哈格古伊
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Excellent Biological Health Co
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Seventh Sense Biosystems Inc
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Expired - Fee Related legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
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    • A—HUMAN NECESSITIES
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    • A61B5/150007—Details
    • A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
    • A61B5/150061—Means for enhancing collection
    • A61B5/150099—Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
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    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150221—Valves
    • A—HUMAN NECESSITIES
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    • A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
    • A61B5/150229—Pumps for assisting the blood sampling
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    • A61B5/150274—Manufacture or production processes or steps for blood sampling devices
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    • A61B5/15107—Piercing being assisted by a triggering mechanism
    • A61B5/15109—Fully automatically triggered, i.e. the triggering does not require a deliberate action by the user, e.g. by contact with the patient's skin
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    • A61B5/15101—Details
    • A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15117—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
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    • A61B5/15115—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids
    • A61B5/15125—Driving means for propelling the piercing element to pierce the skin, e.g. comprising mechanisms based on shape memory alloys, magnetism, solenoids, piezoelectric effect, biased elements, resilient elements, vacuum or compressed fluids comprising a vacuum or compressed fluids
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    • A61B5/15142—Devices intended for single use, i.e. disposable
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    • A61B5/15186—Devices loaded with a single lancet, i.e. a single lancet with or without a casing is loaded into a reusable drive device and then discarded after use; drive devices reloadable for multiple use
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    • A61M5/42—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for desensitising skin, for protruding skin to facilitate piercing, or for locating point where body is to be pierced
    • A61M5/425—Protruding skin to facilitate piercing, e.g. vacuum cylinders, vein immobilising means

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Manufacturing & Machinery (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Optics & Photonics (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
CN201080055393.6A 2009-10-30 2010-10-29 施加到皮肤的较小装置、模块化系统及其使用方法 Expired - Fee Related CN102648015B (zh)

Applications Claiming Priority (27)

Application Number Priority Date Filing Date Title
US25691009P 2009-10-30 2009-10-30
US25687109P 2009-10-30 2009-10-30
US25693309P 2009-10-30 2009-10-30
US25688009P 2009-10-30 2009-10-30
US25693109P 2009-10-30 2009-10-30
US25687409P 2009-10-30 2009-10-30
US25686309P 2009-10-30 2009-10-30
US61/256,874 2009-10-30
US61/256,880 2009-10-30
US61/256,931 2009-10-30
US61/256,910 2009-10-30
US61/256,871 2009-10-30
US61/256,863 2009-10-30
US61/256,933 2009-10-30
US29454310P 2010-01-13 2010-01-13
US61/294,543 2010-01-13
US33452910P 2010-05-13 2010-05-13
US33453310P 2010-05-13 2010-05-13
US61/334,533 2010-05-13
US61/334,529 2010-05-13
US35758210P 2010-06-23 2010-06-23
US61/357,582 2010-06-23
US36760710P 2010-07-26 2010-07-26
US61/367,607 2010-07-26
US37376410P 2010-08-13 2010-08-13
US61/373,764 2010-08-13
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EP2493536A2 (en) 2012-09-05
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